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Stein D L DL Department of Fisheries and Wildlife, Nash Hall 104, Oregon State University, Corvallis, OR 97331, - - 2014
Paraliparis hawaiiensis n.sp. is described from the north-western Hawaiian Islands from two specimens collected at 2196 and 3055 m. It differs from other North Pacific Ocean species in its chin pore arrangement, tooth pattern and body proportions. Although liparid specimens have previously been collected from Hawaii, they were undescribed and are ...
Owings Richard A RA From the Department of Pathology, University of Arkansas for Medical Sciences, Little - - 2014
Context.-Developed in conjunction with molecular and progression data, the sequence classification schema for endometrial intraepithelial neoplasia (EIN)/benign hyperplasia (BH) provides an easy to adopt and reproducible method for classification of endometrial biopsies. Objective.-To review current data supporting the use of BH/EIN to classify endometrial biopsies, and to discuss the hormone-driven ...
Boltersdorf Stefanie H SH Department of Geobotany, University of Trier, Behringstr. 21, D-54296 Trier, Germany. Electronic address: - - 2014
To compare three biomonitoring techniques for assessing nitrogen (N) pollution in Germany, 326 lichen, 153 moss and 187 bark samples were collected from 16 sites of the national N deposition monitoring network. The analysed ranges of N content of all investigated biomonitors (0.32%-4.69%) and the detected δ(15)N values (-15.2‰-1.5‰), made ...
Maybury C M CM St John's Institute of Dermatology, Division of Genetics and Molecular Medicine, King's College London School of Medicine, King's College London, London, - - 2014
People with psoriasis taking methotrexate may be at increased risk of developing liver fibrosis compared to the general population. Non-invasive methods of detecting fibrosis have been widely adopted but their clinical utility is uncertain. To evaluate the diagnostic accuracy of non-invasive methods to detect fibrosis compared to liver biopsy (reference ...
Xu Shuoyu S Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, #04-01, Singapore 138669; Computation and System Biology Program, Singapore-MIT Alliance, 4 Engineering Drive 3, E4-04-10, Singapore 117576; Biosystems and Micromechanics IRG, Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, #04-13/14 Enterprise Wing, Singapore - - 2014
There is increasing need for accurate assessment of liver fibrosis/cirrhosis. We aimed to develop qFibrosis, a fully-automated assessment method combining quantification of histopathological architectural features, to address unmet needs in core biopsy evaluation of fibrosis in chronic hepatitis B (CHB) patients. qFibrosis was established as a combined index based on ...
Nasser Y Y Gastrointestinal Diseases Research Unit, Kingston General Hospital, Queen's University, Kingston, ON, - - 2014
Although animal models of the irritable bowel syndrome (IBS) have provided important insights, there are no models that fully express the features of this complex condition. One alternative approach is the use of human intestinal biopsies obtained during endoscopic procedures to examine peripheral mechanisms in this disorder. These studies have ...
Reble Carina C Laser- und Medizin-Technologie GmbH, Berlin (LMTB), Fabeckstraße 60-62, 14195 BerlinbTechnical University Berlin, Institute for Optics and Atomic Physics, 10587 - - 2014
ABSTRACT. Raman spectroscopy based discrimination of cervical precancer and normal tissue has been shown previously in vivo with fiber probe based measurements of colposcopically selected sites. With a view to developing in vivo large area imaging, macro raster scans of native cervical cone biopsies with an average of 200 spectra ...
McKinney Melissa A MA Department of Biology, Dalhousie University Halifax, Nova Scotia, B3H 4R2, Canada ; Great Lakes Institute for Environmental Research, University of Windsor Windsor, Ontario, N9B 3P4, - - 2014
Body condition is a key indicator of individual and population health. Yet, there is little consensus as to the most appropriate condition index (CI), and most of the currently used CIs have not been thoroughly validated and are logistically challenging. Adipose samples from large datasets of capture biopsied, remote biopsied, ...
Hsiang Solomon M SM Goldman School of Public Policy, University of California, Berkeley, CA - - 2014
A recent study by Burke et al. [Burke M, Miguel E, Satyanath S, Dykema J, Lobell D (2009) Proc Natl Acad Sci USA 106(49):20670-20674] reports statistical evidence that the likelihood of civil wars in African countries was elevated in hotter years. A following study by Buhaug [Buhaug H (2010) Proc ...
Gregori Josep J Liver Unit. Internal Medicine. Vall d'Hebron Institut Recerca (VHIR-HUVH), Barcelona. Roche Diagnostics SL, Sant Cugat del Vallès, Spain. Statistics Department, Biology Faculty, Barcelona University. CIBER de Enfermedades Hepáticas y Digestivas (CIBERehd) del Instituto de Salud Carlos III, Madrid. Centro de Biología Molecular Severo Ochoa (CSIC-UAM). Campus de Cantoblanco. Madrid, Spain. Bioinformatics and Statistics Unit, Vall d'Hebron Institut Recerca (VHIR-HUVH), Bnc. Biochemistry Unit. Virology Unit /Microbiology Department. HUVH, Barcelona. Spain. Universitat Autònoma de Barcelona. Bellaterra. - - 2014
Given the inherent dynamics of a viral quasispecies we are often interested in the comparison of diversity indices of sequential samples of a patient, or in the comparison of diversity indices of virus in groups of patients in a treated versus control design. It is then important to make sure ...
Tang Wenlong - - 2014
Monitoring of postures and activities is used in many clinical and research applications, some of which may require highly reliable posture and activity recognition with desired accuracy well above 99% mark. This paper suggests a method for performing highly accurate recognition of postures and activities from data collected by a ...
Avouac Jérôme J Université Paris Descartes, Service de Rhumatologie A et INSERM U1016, Hôpital, Cochin, Paris, France, - - 2014
Relevant animal models are essential tools to investigate in depth the pathogenesis of autoimmune disease. Systemic sclerosis (SSc) is an autoimmune connective tissue disorder that affects particularly the skin. SSc is characterized by vasculopathy, immune disturbances, and fibrosis. Expression of each of the three pathologic features varies among SSc patients ...
Konijeti Gauree Gupta - - 2013
Recent studies report that the risk of colorectal cancer (CRC) among patients with ulcerative colitis (UC) may be lower than previously estimated. Although white-light endoscopy (WLE) with random biopsies is recommended for dysplasia detection in patients with UC, several studies reported increased detection of dysplasia by chromoendoscopy. To analyze the ...
Yablonskiy Dmitriy A - - 2013
In a recently published paper by Parra-Robles and Wild [1], the authors challenge the in vivo lung morphometry technique (based on hyperpolarized gas diffusion MRI) developed by our Washington University research group. In this Commentary we demonstrate that the main conclusion of Parra-Robles and Wild, that our MRI-based lung morphometry ...
Helal Mohamed - - 2013
We introduce a mathematical model of the in vivo progression of Alzheimer's disease with focus on the role of prions in memory impairment. Our model consists of differential equations that describe the dynamic formation of [Formula: see text]-amyloid plaques based on the concentrations of A[Formula: see text] oligomers, PrP(C) proteins, and the A[Formula: ...
Fiard Gaelle - - 2013
Introduction-objectives: A virtual-reality learning environment dedicated to prostate biopsies was designed to overcome the limitations of current classical teaching methods. The aim of this study was to validate reliability, face, content and construct of the simulator. Materials and methods: The simulator is composed of a) a laptop computer, b) a ...
Wan Ruijie - - 2013
The aim of the present study was to establish noninvasive diagnostic models of liver fibrosis and assess their predictive accuracy (AC). A total of 349 patients with chronic hepatitis B virus infection were collected, who underwent liver biopsy and pathologic examination at Beijing Ditan Hospital affiliated to Capital Medical University. ...
Kubota Jennifer T - - 2013
Existing stereotypes about Black Americans may influence perceptions of intent during financial negotiations. In this study, we explored whether the influence of race on economic decisions extends to choices that are costly to the decision maker. We investigated whether racial group membership contributes to differential likelihood of rejection of objectively ...
Haas Mark - - 2013
The value of classification systems applied to the examination of renal biopsies is based on several factors: first, on the ability to provide efficient communication between pathologists and between pathologists and clinicians; second, on the possibility to implement diagnostic information with prognostic indication. Even more important, the practical value of ...
Vencalek Ondrej - - 2013
To present a new predictive model for repeated prostate biopsy outcomes. Several practical problems are described that arise when searching for a proper model among those that already exist. A new model is developed with only two explanatory variables and a simple graphical output. This is a retrospective cohort study ...
Busetto Gian Maria - - 2013
To overcome the well-known prostate-specific antigen limits, several new biomarkers have been proposed. Since its introduction in clinical practice, the urinary prostate cancer gene 3 (PCA3) assay has shown promising results for prostate cancer (PC) detection. Furthermore, multiparametric magnetic resonance imaging (mMRI) has the ability to better describe several aspects ...
Yim Sehyuk - - 2013
This paper proposes a new wireless biopsy method where a magnetically actuated untethered soft capsule endoscope (MASCE) carries and releases a large number of thermo-sensitive, untethered micro-grippers (¿-grippers) at a desired location inside the stomach and retrieves them after they self-fold and grab tissue samples. We describe the working principles ...
Macek Petr - - 2013
Objectives: To assess the accuracy of prostate histoscanning (PHS) for spatial detection and localization of PCa. Patients and methods: Prospective, single center study from January to September 2012 was conducted. Inclusion criterion was biopsy confirmed PCa in patients scheduled for radical prostatectomy. Totally, 98 patients were included in the study. ...
Miller J Michael - - 2013
A widely-perceived requirement for validation of all new specimen collection swabs by the laboratory appears to be the result of misinformation.…
Menhadji Ashleigh - - 2013
To improve the understanding of the epidemiology of renal cortical neoplasms through pretreatment biopsy, we evaluated a facilitated ultrasound targeting (FUT) technology. The technology allows a needle to be passed through the transducer probe and guided along a virtual dotted line on the monitor. We compared the FUT with standard percutaneous ...
Hendren Nathaniel - - 2013
Across a wide set of non-group insurance markets, applicants are rejected based on observable, often high-risk, characteristics. This paper argues that private information, held by the potential applicant pool, explains rejections. I formulate this argument by developing and testing a model in which agents may have private information about their ...
Craven Anthea - - 2013
The systemic vasculitides are a group of uncommon diseases characterized by blood vessel inflammation. There are currently no diagnostic criteria for the primary systemic vasculitides and physicians must rely on experience and disease definitions. The absence of validated criteria can result in delays in making the correct diagnosis and starting ...
Emerson Joanne B - - 2013
It is widely stated that viruses represent the most significant source of biodiversity on Earth, yet characterizing the diversity of viral assemblages in natural systems remains difficult. Viral diversity studies are challenging because viruses lack universally present, phylogenetically informative genes. Here, we developed an approach to estimate viral diversity using ...
Shepherd Jennifer H - - 2013
Tendon injuries, often called tendinopathies, are debilitating and painful conditions, generally considered to develop as a result of tendon overuse. The aetiology of tendinopathy remains poorly understood, and whilst tendon biopsies have provided some information concerning tendon appearance in late-stage disease, there is still little information concerning the mechanical and ...
Xue Lili - - 2013
The lip biopsy is essential for the diagnosis of primary Sjogren's syndrome (SS) but an invasive method can cause some disadvantages. The purpose of this study is to apply Raman spectroscopy to detect the pathological minor salivary glands in primary SS and establish the diagnostic model of Raman spectra of ...
Villard P F - - 2013
   Training in Interventional Radiology currently uses the apprenticeship model, where clinical and technical skills of invasive procedures are learnt during practice in patients. This apprenticeship training method is increasingly limited by regulatory restrictions on working hours, concerns over patient risk through trainees' inexperience and the variable exposure to case mix ...
Serrano-Falcón C - - 2013
Hair and scalp evaluation techniques can be classified into 3 categories: noninvasive methods (clinical history, general examination, inspection and palpation of the hair and scalp, photography, dermoscopy, etc.); semi-invasive methods (the trichogram); and invasive methods (biopsy). In this article, we provide a practical guide on how to evaluate hair and ...
Skums Pavel - - 2013
Highly mutable RNA viruses exist in infected hosts as heterogeneous populations of genetically close variants known as quasispecies. Next-generation sequencing (NGS) allows for analysing a large number of viral sequences from infected patients, presenting a novel opportunity for studying the structure of a viral population and understanding virus evolution, drug ...
Hilton Eric J - - 2013
The prowfish, Zaprora silenus, is the sole member of the family Zaproridae. It is a large, relatively elongate species with a robust head and body, and it feeds primarily on jellyfishes. Although the larvae and juveniles are pelagic, the adults are demersal, and the species is widely distributed from Southern ...
Bostwick David G - - 2013
Improved methods such as radiofrequency identification (RFID) are needed to optimize specimen tracking in anatomical pathology. We undertook a study of RFID in an effort to optimize specimen tracking and patient identification, including the following: (1) creation of workflow process maps, (2) evaluation of existing RFID hardware technologies, (3) creation ...
Ardeshir Amir - - 2013
Idiopathic chronic diarrhea (ICD) is a common cause of morbidity and mortality among juvenile rhesus macaques. While lesions may be absent at colonoscopy, the histopathologic evaluation of the biopsy specimens is consistent with human macroscopic colitis (MC). In this study, we developed an isotropic uniform random sampling method to evaluate ...
Veeraraghavalu Karthikeyan - - 2013
Cramer et al. (Reports, 23 March 2012, p. 1503; published online 9 February 2012) reported that bexarotene rapidly reduces β-amyloid (Aβ) levels and plaque burden in two mouse models of Aβ deposition in Alzheimer's disease (AD). We now report that, although bexarotene reduces soluble Aβ40 levels in one of the ...
Nishikawa Robert M - - 2013
RATIONALE AND OBJECTIVES: The goal of this study was to determine the accuracy and precision of using scores from a receiver operating characteristic rating scale to estimate sensitivity and specificity. MATERIALS AND METHODS: We used data collected in a previous study that measured the improvements in radiologists' ability to classify ...
Shirts Brian H - - 2013
BACKGROUND: Interpretation of a diagnostic test result requires knowing what proportion of patients with a "similar" result has the condition in question. This information is often not readily available from the medical literature, or may be based on different clinical populations that make it nonapplicable. In certain settings, where correlated ...
Cardesi E - - 2013
From a solely morphological point of view, histopathological diagnosis is subject to interpretation variables that may be investigated from an epistemological aspect. On the basis of the most suitable ways of approach, the authors examine some theoretical aspects involved in writing a histopathological report. In particular, the following are considered: ...
Scotton Chris J - - 2013
Research into the pathogenesis underlying the development of idiopathic pulmonary fibrosis (IPF) is hampered by a repertoire of animal models which fail to recapitulate all the features of the human disease. Better use and understanding of what the animal models represent may improve clinical predictability. We interrogated ex vivo micro-Computed ...
Medford Andrew Rl - - 2013
Pulmonary nodule biopsy: also consider bronchoscopic techniques The value of the COMPASS model in postgraduate training.
Lee D C DC Byrd Alzheimer's Institute, University of South Florida, Tampa, FL 33613, - - 2013
The inflammation hypothesis of Alzheimer's pathogenesis has directed much scientific effort towards ameliorating this disease. The development of mouse models of amyloid deposition permitted direct tests of the proposal that amyloid-activated microglia could cause neurodegeneration in vivo. Many approaches to manipulating microglial activation have been applied to these mouse models, ...
McKeigue Paul M PM Centre for Population Health Sciences, Medical School, University of Edinburgh, Teviot Place, Edinburgh EH9 9AG, United Kingdom. - - 2013
We describe statistical methods that extend the application of admixture mapping from unrelated individuals to nuclear pedigrees, allowing existing pedigree-based collections to be fully exploited. Computational challenges have been overcome by developing a fast algorithm that exploits the factorial structure of the underlying model of ancestry transitions. This has been ...
Ma Jing - - 2013
PURPOSE: Few studies have evaluated the validity of noninvasive models for the diagnosis of liver fibrosis in chronic hepatitis B (CHB) patients, with controversial results. In this study, we evaluated the ability of seven noninvasive models in staging liver fibrosis in a large cohort of CHB. METHODS: This is a ...
Schluesener Jan K - - 2013
Nanomaterials are a challenge to toxicology. The high diversity of novel materials and products will require extensive expertize for evaluation and regulatory efforts. Nanomaterials are of substantial scientific and economic potential. Here, we will focus on nanosilver, a material not only with medical applications, but a rapidly increasing use in ...
de Vasconcelos Melo Francisco Tiago - - 2013
Brasicystis bennetti Thatcher, 1979 was first described from specimens obtained from the subcutaneous tissues of the mouth and operculum of Plagioscyion squamosissimus from the Amazon River in Brazil, however since 2008, Brasicystis has been considered a genus inquirendum. This study reviews some of the diagnostic characters from the original description ...
Pfeifer John D - - 2013
Occult specimen provenance complications (SPCs), which occur when there is an absence of any direct or indirect indication that a specimen switch or contamination may have occurred, constitute a significant patient safety and medical-legal problem because they can lead to misdiagnosis. However, the rate at which occult SPCs occur is ...
Hariri Tabrizi Sanaz - - 2013
ABSTRACT. We have assessed the value of single fiber reflectance (SFR) spectroscopy in prediction of cervical squamous intraepithelial lesions (SIL). SFR was used to measure reflected light from 32 patients undergoing standard colposcopy. Seven parameters extracted from the spectra in addition to two biographic parameters were compared in biopsy-confirmed SIL ...
Torralba-Burrial Antonio - - 2013
Odonata are represented from the Iberian Peninsula by 79 species. However, there exists a significant gap in accessible knowledge about these species,especially regarding their distribution. This data paper describes the specimen-based Odonata data of the Arthropod Collection of the Department of Biología de Organismos y Sistemas (BOS), University of Oviedo, ...
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