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Wan Ruijie - - 2013
The aim of the present study was to establish noninvasive diagnostic models of liver fibrosis and assess their predictive accuracy (AC). A total of 349 patients with chronic hepatitis B virus infection were collected, who underwent liver biopsy and pathologic examination at Beijing Ditan Hospital affiliated to Capital Medical University. ...
Kubota Jennifer T - - 2013
Existing stereotypes about Black Americans may influence perceptions of intent during financial negotiations. In this study, we explored whether the influence of race on economic decisions extends to choices that are costly to the decision maker. We investigated whether racial group membership contributes to differential likelihood of rejection of objectively ...
Haas Mark - - 2013
The value of classification systems applied to the examination of renal biopsies is based on several factors: first, on the ability to provide efficient communication between pathologists and between pathologists and clinicians; second, on the possibility to implement diagnostic information with prognostic indication. Even more important, the practical value of ...
Vencalek Ondrej - - 2013
To present a new predictive model for repeated prostate biopsy outcomes. Several practical problems are described that arise when searching for a proper model among those that already exist. A new model is developed with only two explanatory variables and a simple graphical output. This is a retrospective cohort study ...
Busetto Gian Maria - - 2013
To overcome the well-known prostate-specific antigen limits, several new biomarkers have been proposed. Since its introduction in clinical practice, the urinary prostate cancer gene 3 (PCA3) assay has shown promising results for prostate cancer (PC) detection. Furthermore, multiparametric magnetic resonance imaging (mMRI) has the ability to better describe several aspects ...
Yim Sehyuk - - 2013
This paper proposes a new wireless biopsy method where a magnetically actuated untethered soft capsule endoscope (MASCE) carries and releases a large number of thermo-sensitive, untethered micro-grippers (¿-grippers) at a desired location inside the stomach and retrieves them after they self-fold and grab tissue samples. We describe the working principles ...
Macek Petr - - 2013
Objectives: To assess the accuracy of prostate histoscanning (PHS) for spatial detection and localization of PCa. Patients and methods: Prospective, single center study from January to September 2012 was conducted. Inclusion criterion was biopsy confirmed PCa in patients scheduled for radical prostatectomy. Totally, 98 patients were included in the study. ...
Menhadji Ashleigh - - 2013
To improve the understanding of the epidemiology of renal cortical neoplasms through pretreatment biopsy, we evaluated a facilitated ultrasound targeting (FUT) technology. The technology allows a needle to be passed through the transducer probe and guided along a virtual dotted line on the monitor. We compared the FUT with standard percutaneous ...
Hendren Nathaniel - - 2013
Across a wide set of non-group insurance markets, applicants are rejected based on observable, often high-risk, characteristics. This paper argues that private information, held by the potential applicant pool, explains rejections. I formulate this argument by developing and testing a model in which agents may have private information about their ...
Craven Anthea - - 2013
The systemic vasculitides are a group of uncommon diseases characterized by blood vessel inflammation. There are currently no diagnostic criteria for the primary systemic vasculitides and physicians must rely on experience and disease definitions. The absence of validated criteria can result in delays in making the correct diagnosis and starting ...
Emerson Joanne B JB Department of Earth and Planetary Science, University of California, Berkeley, Berkeley, California, - - 2013
It is widely stated that viruses represent the most significant source of biodiversity on Earth, yet characterizing the diversity of viral assemblages in natural systems remains difficult. Viral diversity studies are challenging because viruses lack universally present, phylogenetically informative genes. Here, we developed an approach to estimate viral diversity using ...
Shepherd Jennifer H JH Institute of Bioengineering, School of Engineering and Materials Science, Queen Mary, University of London, London E1 4NS, UK. - - 2013
Tendon injuries, often called tendinopathies, are debilitating and painful conditions, generally considered to develop as a result of tendon overuse. The aetiology of tendinopathy remains poorly understood, and whilst tendon biopsies have provided some information concerning tendon appearance in late-stage disease, there is still little information concerning the mechanical and ...
Xue Lili - - 2013
The lip biopsy is essential for the diagnosis of primary Sjogren's syndrome (SS) but an invasive method can cause some disadvantages. The purpose of this study is to apply Raman spectroscopy to detect the pathological minor salivary glands in primary SS and establish the diagnostic model of Raman spectra of ...
Villard P F - - 2013
   Training in Interventional Radiology currently uses the apprenticeship model, where clinical and technical skills of invasive procedures are learnt during practice in patients. This apprenticeship training method is increasingly limited by regulatory restrictions on working hours, concerns over patient risk through trainees' inexperience and the variable exposure to case mix ...
Serrano-Falcón C - - 2013
Hair and scalp evaluation techniques can be classified into 3 categories: noninvasive methods (clinical history, general examination, inspection and palpation of the hair and scalp, photography, dermoscopy, etc.); semi-invasive methods (the trichogram); and invasive methods (biopsy). In this article, we provide a practical guide on how to evaluate hair and ...
Skums Pavel - - 2013
Highly mutable RNA viruses exist in infected hosts as heterogeneous populations of genetically close variants known as quasispecies. Next-generation sequencing (NGS) allows for analysing a large number of viral sequences from infected patients, presenting a novel opportunity for studying the structure of a viral population and understanding virus evolution, drug ...
Hilton Eric J - - 2013
The prowfish, Zaprora silenus, is the sole member of the family Zaproridae. It is a large, relatively elongate species with a robust head and body, and it feeds primarily on jellyfishes. Although the larvae and juveniles are pelagic, the adults are demersal, and the species is widely distributed from Southern ...
Bostwick David G - - 2013
Improved methods such as radiofrequency identification (RFID) are needed to optimize specimen tracking in anatomical pathology. We undertook a study of RFID in an effort to optimize specimen tracking and patient identification, including the following: (1) creation of workflow process maps, (2) evaluation of existing RFID hardware technologies, (3) creation ...
Ardeshir Amir - - 2013
Idiopathic chronic diarrhea (ICD) is a common cause of morbidity and mortality among juvenile rhesus macaques. While lesions may be absent at colonoscopy, the histopathologic evaluation of the biopsy specimens is consistent with human macroscopic colitis (MC). In this study, we developed an isotropic uniform random sampling method to evaluate ...
Veeraraghavalu Karthikeyan - - 2013
Cramer et al. (Reports, 23 March 2012, p. 1503; published online 9 February 2012) reported that bexarotene rapidly reduces β-amyloid (Aβ) levels and plaque burden in two mouse models of Aβ deposition in Alzheimer's disease (AD). We now report that, although bexarotene reduces soluble Aβ40 levels in one of the ...
Nishikawa Robert M - - 2013
RATIONALE AND OBJECTIVES: The goal of this study was to determine the accuracy and precision of using scores from a receiver operating characteristic rating scale to estimate sensitivity and specificity. MATERIALS AND METHODS: We used data collected in a previous study that measured the improvements in radiologists' ability to classify ...
Shirts Brian H - - 2013
BACKGROUND: Interpretation of a diagnostic test result requires knowing what proportion of patients with a "similar" result has the condition in question. This information is often not readily available from the medical literature, or may be based on different clinical populations that make it nonapplicable. In certain settings, where correlated ...
Cardesi E - - 2013
From a solely morphological point of view, histopathological diagnosis is subject to interpretation variables that may be investigated from an epistemological aspect. On the basis of the most suitable ways of approach, the authors examine some theoretical aspects involved in writing a histopathological report. In particular, the following are considered: ...
Scotton Chris J - - 2013
Research into the pathogenesis underlying the development of idiopathic pulmonary fibrosis (IPF) is hampered by a repertoire of animal models which fail to recapitulate all the features of the human disease. Better use and understanding of what the animal models represent may improve clinical predictability. We interrogated ex vivo micro-Computed ...
Medford Andrew Rl - - 2013
Pulmonary nodule biopsy: also consider bronchoscopic techniques The value of the COMPASS model in postgraduate training.
Lee D C DC Byrd Alzheimer's Institute, University of South Florida, Tampa, FL 33613, - - 2013
The inflammation hypothesis of Alzheimer's pathogenesis has directed much scientific effort towards ameliorating this disease. The development of mouse models of amyloid deposition permitted direct tests of the proposal that amyloid-activated microglia could cause neurodegeneration in vivo. Many approaches to manipulating microglial activation have been applied to these mouse models, ...
McKeigue Paul M PM Centre for Population Health Sciences, Medical School, University of Edinburgh, Teviot Place, Edinburgh EH9 9AG, United Kingdom. - - 2013
We describe statistical methods that extend the application of admixture mapping from unrelated individuals to nuclear pedigrees, allowing existing pedigree-based collections to be fully exploited. Computational challenges have been overcome by developing a fast algorithm that exploits the factorial structure of the underlying model of ancestry transitions. This has been ...
Ma Jing - - 2013
PURPOSE: Few studies have evaluated the validity of noninvasive models for the diagnosis of liver fibrosis in chronic hepatitis B (CHB) patients, with controversial results. In this study, we evaluated the ability of seven noninvasive models in staging liver fibrosis in a large cohort of CHB. METHODS: This is a ...
Schluesener Jan K - - 2013
Nanomaterials are a challenge to toxicology. The high diversity of novel materials and products will require extensive expertize for evaluation and regulatory efforts. Nanomaterials are of substantial scientific and economic potential. Here, we will focus on nanosilver, a material not only with medical applications, but a rapidly increasing use in ...
de Vasconcelos Melo Francisco Tiago - - 2013
Brasicystis bennetti Thatcher, 1979 was first described from specimens obtained from the subcutaneous tissues of the mouth and operculum of Plagioscyion squamosissimus from the Amazon River in Brazil, however since 2008, Brasicystis has been considered a genus inquirendum. This study reviews some of the diagnostic characters from the original description ...
Pfeifer John D - - 2013
Occult specimen provenance complications (SPCs), which occur when there is an absence of any direct or indirect indication that a specimen switch or contamination may have occurred, constitute a significant patient safety and medical-legal problem because they can lead to misdiagnosis. However, the rate at which occult SPCs occur is ...
Hariri Tabrizi Sanaz - - 2013
ABSTRACT. We have assessed the value of single fiber reflectance (SFR) spectroscopy in prediction of cervical squamous intraepithelial lesions (SIL). SFR was used to measure reflected light from 32 patients undergoing standard colposcopy. Seven parameters extracted from the spectra in addition to two biographic parameters were compared in biopsy-confirmed SIL ...
Torralba-Burrial Antonio - - 2013
Odonata are represented from the Iberian Peninsula by 79 species. However, there exists a significant gap in accessible knowledge about these species,especially regarding their distribution. This data paper describes the specimen-based Odonata data of the Arthropod Collection of the Department of Biología de Organismos y Sistemas (BOS), University of Oviedo, ...
Anthony Simon J - - 2013
ABSTRACT The majority of emerging zoonoses originate in wildlife, and many are caused by viruses. However, there are no rigorous estimates of total viral diversity (here termed "virodiversity") for any wildlife species, despite the utility of this to future surveillance and control of emerging zoonoses. In this case study, we ...
Sowa Jan-Peter JP Department of Gastroenterology and Hepatology, University Hospital, University Duisburg-Essen, Essen, - - 2013
Various conditions of liver disease and the downsides of liver biopsy call for a non-invasive option to assess liver fibrosis. A non-invasive score would be especially useful to identify patients with slow advancing fibrotic processes, as in Non-Alcoholic Fatty Liver Disease (NAFLD), which should undergo histological examination for fibrosis. Classic ...
Tang Liang L Department of Biology, Shanghai Normal University, 100 Guilin Road, 1st Educational Building 323 Room, Shanghai, 200234 P. R. - - 2013
Brathinus satoi Kishimoto & Shimada, 2003 is recorded from Longwangshan Nature Reserve, Zhejiang, China. Some diagnostic characters of the species are discussed based on more specimens, and some biological notes are made on the species.
Luo Yongting Y Department of Biology, Shanghai Normal University, Guilin Road 100, Shanghai, - - 2013
During the study of rotifers collected in Eastern DR Congo, we rediscovered specimens that correspond to Monostyla dorsicornuta Van Oye, 1926. This species, which we redescribe, had not been seen since it's summary description, and lacked type material. Our analysis reveals that the animal belongs to Trichotriidae rather than to ...
Hoffmann Dorothee D Museum Wiesbaden - Hessisches Landesmuseum für Kunst und Natur, Naturhistorische Sammlungen, Friedrich-Ebert-Allee 2, 65185 Wiesbaden, - - 2013
Bird specimens collected by 19(th) century explorer and ornithologist Prince Maximilian of Wied-Neuwied form one of the foundation collections of the American Museum of Natural History in New York. However, parts of his collection remained in Germany and came to the Museum Wiesbaden. Since Wied described numerous new species without ...
Yin Zi-Wei ZW Department of Biology, College of Life and Environmental Sciences, Shanghai Normal University, 100 Guilin Road, Shanghai, 200234, P. R. China ; Department of Biology, School of Life Sciences, East China Normal University, 3663 North Zhongshan Road, Shanghai,200062, P. R. - - 2013
Tangius indicus sp. n. (Batrisitae: Batrisini) is described and illustrated from the Indian States of Meghalaya (Khasi Hills, type locality) and West Bengal (Darjeeling). Specimens of the new species are similar to those of the recently described T. glabellus Yin & Li from Tibet, Southwest China, and can be separated ...
Wiig Oystein O Natural History Museum, University of Oslo, POB 1172 Blindern, 0318 Oslo, Norway; Email: - - 2013
A catalog of mammalian type specimens in the collections of Natural History Museum, University of Oslo, Norway, is presented. All type specimens in the Museum's mammal collection were revisited and the respective label information was compared with the data provided in the original descriptions. Most taxa were described from type ...
Malavaud Bernard - - 2012
Abstract Objective: A recent expert study (RAND Appropriateness Method (RAM)) including a panel of 12 European urologists reported that the PCA3 score may be instrumental in taking appropriate prostate biopsy (PBx) decisions, mainly for repeat PBx. This study determined the cost/benefit balance of introducing PCA3 in the decision-making for PBx ...
Wylie Mj - - 2012
Abstract AIM: To establish a method of gonad biopsy for ovarian tissue collection in the declining giant kokopu Galaxias argenteus (Gmelin 1789) as an alternative to lethal sampling in order to understand the species' reproductive biology. METHODS: Six female giant kokopu weighing between 200 and 350 g were caught from the ...
Machado Angelo B M - - 2012
Carajathemis simone n. gen., n.sp. from the state of Pará, Brazil, is described and illustrated based on 22 specimens collected in a "canga" (laterite) lake within the forest at the Flona de Carajás, Parauapebas Municipality. The new libellulid genus fits in the subfamily Sympetrinae and the male keys out to ...
Truong Matthew M University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, - - 2013
We determined whether a novel combination of field defect DNA methylation markers could predict the presence of prostate cancer using histologically normal transrectal ultrasound guided biopsy cores. Methylation was assessed using quantitative Pyrosequencing® in a training set consisting of 65 nontumor and tumor associated prostate tissues from University of Wisconsin. ...
Socolovschi Cristina - - 2012
Canine monocytic ehrlichiosis caused by Ehrlichia canis is distributed globally, but its prevalence in Africa is poorly known. In the study reported herein, 27% of Rhipicephalus sanguineus ticks collected from watchdogs in Abidjan, Ivory Coast, were positive for E. canis using quantitative real-time PCR. A new molecular strategy is proposed ...
Mulder Daniel J - - 2012
ABSTRACT: Diagnosing eosinophilic esophagitis (EoE) depends on intraepithelial eosinophil count of ≥15 eosinophils per high power field (HPF). However, differentiating EoE from gastroesophageal reflux disease (GERD) continues to be a challenge, as no true 'gold standard' criteria exist. Identifying clinical and endoscopic characteristics that distinguish EoE could provide a more ...
Silcox Mary T - - 2012
Primates underwent a period of diversification following the extinction of non-avian dinosaurs. Although the Order first appeared near the Cretaceous-Paleogene boundary, it is not until the Torrejonian (the second North American Land Mammal Age of the Paleocene) that a diversity of families began to emerge. One of the lithological units ...
Hwang Sang-Hyun - - 2012
BACKGROUND: The probability of a prostate cancer-positive biopsy result varies with PSA concentration. Thus, we applied information theory on classification and regression tree analysis (CART) for decision making predicting the probability of a biopsy result at various PSA concentrations. METHODS: From 2007 to 2009, prostate biopsies were performed in 664 ...
Lubina Zvonimir Ivan - - 2012
PURPOSE: To present a new model derived from Ross's model for the assessment of the total amount of epidural fibrosis and to present inter- and intravariability study. METHODS: Two readers blinded to each other and blinded to their first and second reading retrospectively evaluated the magnetic resonance examinations in 32 ...
Agarwal Ritesh - - 2012
BACKGROUND AND AIM: Flexible bronchoscopic procedures are currently the most often employed technique for demonstrating granulomatous inflammation in sarcoidosis. Conventional transbronchial needle aspiration (TBNA) has been used for over three decades; however it remains an underutilized technique, primarily due to the wide variations in the reported success rates and unconfirmed ...
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