Search Results
Results 101 - 150 of 1410
1 2 3 4 5 6 7 8 9 10 >
Chen Wen-Ming WM Department of Mechanical Engineering, Melbourne School of Engineering, University of Melbourne, Victoria, Australia. Electronic address: - - 2014
Material properties of the plantar soft tissue have not been well quantified in vivo (i.e., from life subjects) nor for areas other than the heel pad. This study explored an in vivo investigation of the plantar soft tissue material behavior under the metatarsal head (MTH). We used a novel device ...
Szczesny Spencer E SE Department of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33rd St, Philadelphia, PA 19104, United States. Electronic address: - - 2014
Despite current knowledge of tendon structure, the fundamental deformation mechanisms underlying tendon mechanics and failure are unknown. We recently showed that a shear lag model, which explicitly assumed plastic interfibrillar load transfer between discontinuous fibrils, could explain the multiscale fascicle mechanics, suggesting that fascicle yielding is due to plastic deformation ...
Simon Carl G CG Jr Biosystems and Biomaterials Division, National Institute of Standards and Technology, Gaithersburg, - - 2014
The "Workshop on Standards & Measurements for Tissue Engineering Scaffolds" was held on May 21, 2013 in Indianapolis, IN, and was sponsored by the ASTM International (ASTM). The purpose of the workshop was to identify the highest priority items for future standards work for scaffolds used in the development and ...
Pavan Piero G PG Department of Industrial Engineering, University of Padova, Padova, Italy Centre of Mechanics of Biological Materials, University of Padova, Padova, Italy - - 2014
This work aims to present a constitutive model suitable to interpret the biomechanical response of human pericardial tissues. The model is consistent with the need of describing large strains, anisotropy, almost incompressibility, and time-dependent effects. Attention is given to human pericardial tissue because of the increased interest in its application ...
Shen Jie - - 2014
In this paper, we utilize structured learning to simultaneously address two intertwined problems: human pose estimation (HPE) and garment attribute classification (GAC), which are valuable for a variety of computer vision and multimedia applications. Unlike previous works that usually handle the two problems separately, our approach aims to produce a ...
Conway C C Biomechanics Research Centre (BMEC), Biomedical Engineering, College of Engineering and Informatics, National University of Ireland Galway, Galway, Ireland, - - 2014
A thorough understanding of the diseased tissue state is necessary for the successful treatment of a blocked arterial vessel using stent angioplasty. The constitutive representation of atherosclerotic tissue is of great interest to researchers and engineers using computational models to analyse stents, as it is this in silico environment that ...
Bosch Thomas C G TC Christian-Albrechts-Universität zu Kiel, Kiel, - - 2014
Ecological developmental biology (eco-devo) explores the mechanistic relationships between the processes of individual development and environmental factors. Recent studies imply that some of these relationships have deep evolutionary origins, and may even pre-date the divergences of the simplest extant animals, including cnidarians and sponges. Development of these early diverging metazoans ...
Turiak Lilla - - 2014
Extracellular matrices comprise glycoproteins, glycosaminoglycans, and proteoglycans that order the environment through which cells receive signals and communicate. Proteomic and glycomic molecular signatures from tissue surfaces can add diagnostic power to the immunohistochemistry workflows. Acquired in a spatially resolved manner, such proteomic and glycomic information can help characterize disease processes ...
Joshi Aniket D AD Merck, West Point, PA, United - - 2014
Decreased glutamatergic neurotransmission is hypothesized to be involved in the pathophysiology of schizophrenia. Inhibition of glycine transporter type-1 (GlyT1) reuptake is expected to increase the glutamatergic neurotransmission and may serve as treatment for cognitive and negative symptoms of schizophrenia. In this paper, we present human data from a novel GlyT1 ...
Luboz V V UJF-Grenoble1/CNRS/TIMC-IMAG UMR 5525, Grenoble, 38041, France, - - 2014
Biomechanical modeling of the facial soft tissue behavior is needed in aesthetic or maxillo-facial surgeries where the simulation of the bone displacements cannot accurately predict the visible outcome on the patient's face. Because these tissues have different nature and elastic properties across the face, depending on their thickness, and their ...
Filipe H A L - - 2014
One of the great challenges in pharmacokinetics is to find a means to optimize the transport across cell barriers. In this work, permeation across a cell monolayer, such as the tight endothelia in the Blood Brain Barrier, was modeled using a homologous series of amphipatic molecules, NBD-labeled alkyl chain amphiphiles, ...
Herrera Claudia - - 2014
A novel direct D-bar reconstruction algorithm is presented for reconstructing a complex conductivity distribution from 2-D EIT data. The method is applied to simulated data and archival human chest data. Permittivity reconstructions with the aforementioned method and conductivity reconstructions with the D-bar method based on [22] depicting ventilation and perfusion ...
Reingruber Jürgen J Group of Computational Biology and Applied Mathematics, Institute of Biology (IBENS), CNRS INSERM 1024, Ecole Normale Supérieure, 46 rue d'Ulm, 75005 Paris, France. Electronic address: - - 2014
Morphogenesis and axonal targeting are key processes during development that depend on complex interactions at molecular, cellular and tissue level. Mathematical modeling is essential to bridge this multi-scale gap in order to understand how the emergence of large structures is controlled at molecular level by interactions between various signaling pathways. ...
Cruz G D GD Department of Animal Science, University of California, Davis, CA, 95616, - - 2014
Understanding the mechanisms by which nutritional and pharmaceutical factors can manipulate adipose tissue growth and development in production animals has direct and indirect effects in the profitability of an enterprise. Adipocyte cellularity (number and size) is a key biological response that is commonly measured in animal science research. The variability ...
Pence Jacquelyn C JC Dept. of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801, - - 2014
Strategies to integrate instructive biomolecular signals into a biomaterial are becoming increasingly complex and bioinspired. While a large majority of reports still use repeated treatments with soluble factors, this approach can be prohibitively costly and difficult to translate in vivo for applications where spatial control over signal presentation is necessary. ...
Simon D D DD Department of Biomedical Engineering, Yale University, New Haven, CT, - - 2014
Tissue equivalents represent excellent model systems for elucidating principles of mechanobiology as well as for exploring methods to improve the functionality of tissue engineered constructs. The simplest tissue equivalent is the free-floating fibroblast-populated collagen lattice. Although introduced over 30 years ago, the associated mechanics of the cell-mediated compaction of this lattice ...
Tsartsalis Stergios - - 2014
AbstractDefluorination of [18F]fallypride and accumulation of 18F in skull and glands leads to the contamination of brain structures with spillover activity due to partial volume effects, leading to considerable errors in binding potential estimations. Here we propose a modification of the simplified reference tissue model (SRTM) to take into account ...
Fontanella Chiara Giulia CG Centre for Mechanics of Biological Materials, University of Padova, Padova, Italy - - 2014
The aim of this work is to provide a numerical approach for the investigation of the mechanical behaviour of the forefoot soft tissues. The development of reliable numerical models of biological structures requires the definition of constitutive formulations that actually interpret the mechanical response of the constituent biological tissues and ...
Escobedo Fernando A FA School of Chemical & Biomolecular Engineering, Cornell University, Ithaca, NY 14953, USA. - - 2014
The role of entropic interactions, often subtle and sometimes crucial, on the structure and properties of soft matter has a well-recognized place in the classic and modern scientific literature. However, the lessons learned from many of those studies do not always form part of the standard arsenal of strategies that ...
Rabilloud Thierry T CNRS UMR 5249, Laboratory of Chemistry and Biology of Metals, Grenoble, France; Univ. Grenoble Alpes, Laboratory of Chemistry and Biology of Metals, Grenoble, France; CEA Grenoble, iRTSV/CBM, Laboratory of Chemistry and Biology of Metals, Grenoble, - - 2014
Toxicoproteomics can be defined as the application of proteomic approaches to the understanding of toxicology problems, and this review deals with the various types of applications that have been described in the literature. Toxicoproteomics has been applied to very different classes of toxicants, from drugs and natural products to metals, ...
Oshio Koichi K Department of Diagnostic Radiology, Keio University School of - - 2014
Purpose: Although many models have been proposed to interpret non-Gaussian diffusion MRI data in biological tissues, it is often difficult to see the correlation between the MRI data and the histological changes in the tissue. Among these models, so called statistical models, which assume the diffusion coefficient D is distributed ...
Rockson Stanley G SG Allan and Tina Neill Professor of Lymphatic Research and Medicine; Stanford Center for Lymphatic and Venous Disorders, Stanford University School of Medicine, Stanford, California 94305. Electronic address: - - 2014
Lymphangiomatosis is an uncommon proliferative disorder of lymphatic vasculature whose etiology remains poorly understood. The lymphangiomatosis spectrum encompasses a remarkable heterogeneity in its potential presentation, including micro-and macrocystic isolated lymphatic malformations, thoracic and intraabdominal diffuse lymphangiomatosis, and osseous and soft-tissue presentations known as Gorham-Stout disease. Recent therapeutic advances are empirical ...
Heaps Sarah E - - 2014
Abstract In molecular phylogenetics, standard models of sequence evolution generally assume that sequence composition remains constant over evolutionary time. However, this assumption is violated in many datasets which show substantial heterogeneity in sequence composition across taxa. We propose a model which allows compositional heterogeneity across branches, and formulate the model ...
Arregui Lucia L L Arregui, Department of Biology, Universidad Autonoma de Madrid, Madrid, Spain - - 2014
Spermatogenesis is a dynamic and complex process that involves endocrine and testicular factors. During xenotransplantation of testicular tissue fragments into immunodecifient mouse mice a functional communication between host brain and donor testis is established. This interaction allows for the progression of a normal spermatogenesis and recovery of fertilization-competent spermatozoa from ...
Gosselin Marie-Christine MC Foundation for Research on Information Technologies in Society (IT'IS), Zeughausstrasse 43, 8004 Zurich, Switzerland. ETH Zurich, Zurich, - - 2014
The Virtual Family computational whole-body anatomical human models were originally developed for electromagnetic (EM) exposure evaluations, in particular to study how absorption of radiofrequency radiation from external sources depends on anatomy. However, the models immediately garnered much broader interest and are now applied by over 300 research groups, many from ...
Von Forell Gregory A GA Department of Mechanical Engineering, Brigham Young University, Provo, UT 84602, - - 2014
A full understanding of the mechanisms of action in the percutaneous triple hemisection technique for tendo-achilles lengthening has yet to be acquired and therefore, an accurate prediction of the amount of lengthening that occurs is difficult to make. The purpose of this research was to develop a phenomenological damage model ...
Scioscia Marco M Department of Obstetrics and Gynecology, Sacro Cuore Don Calabria, Negrar, Verona, - - 2014
The accuracy of sonographic estimation of birthweight in suspected macrosomic fetuses is compromised by the imprecision of the biometrical measurements. This prospective study evaluated the performance of an equation based on linear measurement of the soft tissue above the external side of the fetal femur. The performance of this algorithm ...
Latifi Neda N Department of Mechanical Engineering, McGill University, 817 Sherbrooke Street West, Montreal, Canada QC H3A 0C3. Electronic address: - - 2014
The aim of the present study was to quantify the effects of the specimen shape on the accuracy of mechanical properties determined from a shape-specific model generation strategy. Digital images of five rabbit vocal folds (VFs) in their initial undeformed conditions were used to build corresponding specific solid models. The ...
Cortés-Romero John J Universidad Nacional de Colombia, Facultad de Ingeniería, Departamento de Ingeniería Eléctrica y Electrónica, Bogotá D.C., Colombia. Electronic address: - - 2014
Conventional repetitive control has proven to be an effective strategy to reject/track periodic signals with constant frequency; however, it shows poor performance in varying frequency applications. This paper proposes an active disturbance rejection methodology applied to a large class of uncertain flat systems for the tracking and rejection of periodic ...
Hingant Erwan E CI2MA, Universidad de Concepción, Concepción, - - 2014
In a previous work by Alvarez-Martinez et al. (2011), the authors pointed out some fallacies in the mainstream interpretation of the prion amyloid formation. It appeared necessary to propose an original hypothesis able to reconcile the in vitro data with the predictions of a mathematical model describing the problem. Here, ...
Robinson Scott W SW Institute of Cardiovascular and Medical Sciences, University of Glasgow, BHF Glasgow Cardiovascular Research Centre, 126 University Place, Glasgow G12 8TA, - - 2014
Systems biology has gained a tremendous amount of interest in the last few years. This is partly due to the realization that traditional approaches focusing only on a few molecules at a time cannot describe the impact of aberrant or modulated molecular environments across a whole system. Furthermore, a hypothesis-driven ...
Bernabò Nicola N Faculty of Veterinary Medicine, University of Teramo, Piazza Aldo Moro 45, 64100 Teramo, - - 2014
Cellular signal transduction is a complex phenomenon, which plays a central role in cell surviving and adaptation. The great amount of molecular data to date present in literature, together with the adoption of high throughput technologies, on the one hand, made available to scientists an enormous quantity of information, on ...
Titz Bjoern B Philip Morris International R&D, Philip Morris Products S.A., Quai Jeanrenaud 5, 2000 Neuchâtel, - - 2014
Current toxicology studies frequently lack measurements at molecular resolution to enable a more mechanism-based and predictive toxicological assessment. Recently, a systems toxicology assessment framework has been proposed, which combines conventional toxicological assessment strategies with system-wide measurement methods and computational analysis approaches from the field of systems biology. Proteomic measurements are ...
K Hurtado Felipe F Pharmaceutical Sciences Graduate Program, College of Pharmacy, Federal University of Rio Grande do Sul, Av. Ipiranga 2752, 90610-000 Porto Alegre, RS, - - 2014
Moxifloxacin is reported to have increased distribution into the prostate compared with older fluoroquinolones such as norfloxacin and ciprofloxacin, being able to reach tissue-to-plasma concentration ratios greater than unity. However, most of these studies use tissue homogenates derived from biopsy samples, which can lead to overestimation of free concentrations as ...
Morris Eric E a Department of Education and Counselling Psychology , McGill University , Montreal , QC , - - 2014
Abstract Objective: The present paper attempts to differentiate client involvement from other, similar process variables and presents a pan-theoretical conceptualization of client involvement. Method: A modified Delphi poll was conducted with 20 experienced clinicians and researchers. In two rounds of data collection, the experts completed a questionnaire designed to elicit ...
Nava Santiago S Instituto Nacional de Tecnología Agropecuaria, Estación Experimental Agropecuaria Rafaela and Consejo Nacional de Investigaciones Científicas y Técnicas, CC 22, CP 2300 Rafaela, Santa Fe, - - 2014
Herein, Amblyomma tenellumKoch, 1844 (Ixodidae) is reestablished as a valid tick name and removed from the synonymy list of Amblyomma cajennense (Fabricius, 1787), while Amblyomma imitatorKohls, 1958, is relegated to a junior synonym of A. tenellum. Amblyomma tenellum is redescribed based on the examination of male type specimens collected by ...
Shehab H H Department of Endemic medicine, Hepatology Division, Faculty of medicine, Cairo University, Cairo, - - 2014
Staging of liver fibrosis is an integral part of the management of HCV. Liver biopsy is hampered by its invasiveness and possibility of sampling error. Current noninvasive methods are disadvantaged by their cost and complexity. In this study, we aimed at developing a noninvasive method for the staging of liver ...
Paparo Francesco F Department of Radiology, E. O. Ospedali Galliera, Genoa, Italy. Electronic address: - - 2014
Despite its invasiveness, liver biopsy is still considered the gold standard for the assessment of hepatic fibrosis. Non-invasive ultrasound-based techniques are increasingly employed to assess parenchymal stiffness and the progression of chronic diffuse liver diseases. Real-time elastography is a rapidly evolving technique that can reveal the elastic properties of tissues. ...
Silva Amanda K A AK Laboratoire Matière et Systèmes Complexes, UMR 7057 CNRS, Université Paris 7, 10 rue Alice Domon et Léonie Duquet, F-75205 Paris Cedex 13, France; Inserm, U1148, Cardiovascular Bio-Engineering, X. Bichat Hospital, 46 rue H. Huchard, F-75018 Paris, - - 2015
Polysaccharides are abundant biomolecules in nature presenting important roles in a wide variety of living systems processes. Considering the structural and biological functions of polysaccharides, their properties have raised interest for tissue engineering. Herein, we described the latest advances in cardiac tissue engineering mediated by polysaccharides. We reviewed the data ...
Tampucci Silvia S Department of Pharmacy, University of Pisa, Pisa, I-56126, - - 2014
The differential stripping technique consists of a tape-stripping phase followed by a cyanoacrylate biopsy. This technique not only allows the quantification of drug retained in the stratum corneum (SC) and in the hair follicles but also differentiates transepidermal from transfollicular penetration. Our study aimed at both validating the differential stripping ...
O'Sullivan Finbarr F University College - - 2014
Most radiotracers used in dynamic positron emission tomography (PET) scanning act in a linear time-invariant fashion so that the measured time-course data are a convolution between the time course of the tracer in the arterial supply and the local tissue impulse response, known as the tissue residue function. In statistical ...
Lamb Christopher R CR Department of Clinical Sciences and Services, The Royal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hertfordshire, AL9 7TA, - - 2014
Better understanding of the reasons why manuscripts are rejected, and recognition of the most frequent manuscript flaws identified by reviewers, should help submitting authors to avoid these pitfalls. Of 219 manuscripts submitted to Veterinary Radiology & Ultrasound in 2012, none (0%) was accepted without revision, four (2%) were withdrawn by ...
Barclay Pat P Department of Psychology, University of Guelph, Guelph, Ontario, Canada N1G 2W1 - - 2014
Humans reject uneven divisions of resources, even at personal cost. This is observed in countless experiments using the ultimatum game, where a proposer offers to divide a resource with a responder who either accepts the division or rejects it (whereupon both earn zero). Researchers debate why humans evolved a psychology ...
Kiapour Ata M AM Engineering Center for Orthopaedic Research Excellence (ECORE), University of Toledo, Toledo, USA ; Departments of Orthopaedics and Bioengineering, The University of Toledo, Toledo, - - 2014
Finite element (FE) analysis has become an increasingly popular technique in the study of human joint biomechanics, as it allows for detailed analysis of the joint/tissue behavior under complex, clinically relevant loading conditions. A wide variety of modeling techniques have been utilized to model knee joint ligaments. However, the effect ...
Gujarathi S R SR Department of Physics and Astronomy, Michigan State University, East Lansing, Michigan 48824, - - 2014
Reconstruction of complex structures is an inverse problem arising in virtually all areas of science and technology, from protein structure determination to bulk heterostructure solar cells and the structure of nanoparticles. We cast this problem as a complex network problem where the edges in a network have weights equal to ...
Ding Ke K Department of Radiology, The No.2 People's Hospital of Nanning, Nanning 530031, China; Department of Radiology, Affiliated Hospital of Guilin Medical University, Guilin 541000, - - 2014
Hepatic fibrosis, resulted from hepatoxicity and other diseases such as diabetes, is an important pathological characteristic of chronic liver diseases. Establishment of hepatic fibrosis animal models is of great importance and a prerequisite for human clinical studies. The common models for liver fibrosis are often established in lower small animals ...
Schwartz Doron D Virginia Tech - Wake Forest University, - - 2014
A simplified lower extremity model was developed using the geometry from the Global Human Body Models Consortium (GHBMC) 50th percentile male occupant model v4.1.1 (M50) as a base. This simplified model contains 31.4x103 elements and has structures that represent bone (assumed rigid) and soft tissue. This element total is substantially ...
Stein D L DL Department of Fisheries and Wildlife, Nash Hall 104, Oregon State University, Corvallis, OR 97331, - - 2014
Paraliparis hawaiiensis n.sp. is described from the north-western Hawaiian Islands from two specimens collected at 2196 and 3055 m. It differs from other North Pacific Ocean species in its chin pore arrangement, tooth pattern and body proportions. Although liparid specimens have previously been collected from Hawaii, they were undescribed and are ...
Owings Richard A RA From the Department of Pathology, University of Arkansas for Medical Sciences, Little - - 2014
Context.-Developed in conjunction with molecular and progression data, the sequence classification schema for endometrial intraepithelial neoplasia (EIN)/benign hyperplasia (BH) provides an easy to adopt and reproducible method for classification of endometrial biopsies. Objective.-To review current data supporting the use of BH/EIN to classify endometrial biopsies, and to discuss the hormone-driven ...
Lee Seong Cheol SC Department of Surgery, Dankook University College of Medicine, Cheonan, - - 2014
Although sonography-guided core needle biopsy is a highly targeted method, there is a possibility of an invasive component after surgical excision of ductal carcinoma in situ (DCIS) of the breast. This study was performed to develop and validate nomograms to predict the postoperative invasive component in DCIS at core needle ...
1 2 3 4 5 6 7 8 9 10 >