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Banks H Thomas HT Center for Research in Scientific Computation, Center for Quantitative Sciences in Biomedicine, North Carolina State University, Raleigh, NC 27695-8212, United States. - - 2014
A current thrust in medical research is the development of a non-invasive method for detection, localization, and characterization of an arterial stenosis (a blockage or partial blockage in an artery). A method has been proposed to detect shear waves in the chest cavity which have been generated by disturbances in ...
Sundling Kaitlin K Department of Pathology, University of Wisconsin Hospital and Clinics, Madison WI 53792, United States. - - 2014
The rainbow trout endocrine system is sensitive to changes in annual day length, which is likely the principal environmental cue controlling its reproductive cycle. This study focuses on the endocrine regulation of vitellogenin (Vg) protein synthesis, which is the major egg yolk precursor in this fish species. We present a ...
do Nascimento Graziele Elisandra - - 2014
This work proposes the use of agro-industrial wastes, specifically peanut hull (HP) and orange peel (OP), as adsorbents for dyes, such as Remazol Golden Yellow RNL-150% (RYG), Gray Reactive BF-2R (RG) and Reactive Turquoise Q-G125 (RT). Characterization by Brunauer-Emmett-Teller indicates that the adsorbents are mesoporous, with pHzpc values of 5.0 ...
Kelterer Anne-Marie AM Institute of Physical and Theoretical Chemistry, Graz University of Technology, Stremayrgasse 9/I, 8010, Graz, Austria, - - 2014
The vertical excitation energies of 3,4-dicyano-6-methoxy and 3,4-dicyano-6,7-dimethoxy carbostyril have been computed with different approximations for the time-dependent density functional theory (TD-DFT) procedure and with different implementations of the continuum solvation model COSMO. Different DFT functionals were tested in TD-DFT and Tamm-Dancoff approximations (TDA) for the excitation energies in the ...
Kancharala A K AK Aerospace and Ocean Engineering, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061, - - 2014
The caudal fin is a major source of thrust generation in fish locomotion. Along with the fin stiffness, the stiffness of the joint connecting the fish body to the tail plays a major role in the generation of thrust. This paper investigates the combined effect of fin and joint flexibility ...
Kramer Christian C Department of Theoretical Chemistry, Faculty for Chemistry and Pharmacy, Center for Molecular Biosciences Innsbruck (CMBI), Leopold-Franzens University Innsbruck , Innrain 80/82, A-6020 Innsbruck, - - 2014
Matched molecular pair analysis (MMPA) has become a major tool for analyzing large chemistry data sets for promising chemical transformations. However, the dependence of MMPA predictions on data constraints such as the number of pairs involved, experimental uncertainty, source of the experiments, and variability of the true physical effect has ...
Soler J J JJ Departamento de Ecología Funcional y Evolutiva, Estación Experimental de Zonas Áridas - CSIC, Almería, Spain; Grupo Coevolución, Unidad Asociada al CSIC, Universidad de Granada, Granada, - - 2014
One of the most important defensive host traits against brood parasitism is the detection and ejection of parasitic eggs from their nests. Here, we explore the possible role of olfaction in this defensive behaviour. We performed egg-recognition tests in magpie Pica pica nests with model eggs resembling those of parasitic ...
Wu John Z JZ National Institute for Occupational Safety and Health, Morgantown, WV, USA. Electronic address: - - 2014
Contact interactions between the hand and handle, such as the contact surface softness and contact surface curvature, will affect both physical effort and musculoskeletal fatigue, thereby the comfort and safety of power tool operations. Previous models of hand gripping can be categorized into two groups: multi-body dynamic models and finite ...
Stevenson Ryan A RA Department of Psychology, University of Toronto, Toronto, ON, Canada, - - 2014
We process information from the world through multiple senses, and the brain must decide what information belongs together and what information should be segregated. One challenge in studying such multisensory integration is how to quantify the multisensory interactions, a challenge that is amplified by the host of methods that are ...
Thinová L L CTU in Prague, FNSPE, DDAIR, BÅ™ehová 7, 115 19 Praha 1, Czech - - 2014
The radon concentration in underground workplaces may reach tens of thousands of Bq m(-3). A simple MCNPX(TM) Monte Carlo (MC) model of a cave was developed to estimate the influence of radon on the in situ gamma spectrometry results in various geometries and radon concentrations. The detector total count rate ...
Martín Sánchez A A Department of Physics, University of Extremadura, 06006 Badajoz, - - 2014
Measurements of radon concentration may not be sufficiently representative for the cumulative total exposure suffered by a person throughout his life. Retrospective dosimetry can help estimating from the direct measurement of (210)Po (descendant of (222)Rn) implanted on surfaces, because this quantity is related (through the conversion factor) with the mean ...
Gajewska M M Systems Toxicology Unit and EURL ECVAM, Institute for Health and Consumer Protection, European Commission, Joint Research Centre, 21027 Ispra (VA), Italy; University of Milano Biccoca, Dep. of Earth and Environmental Sciences, Piazza della Scienza 1, Milano, Italy. Electronic address: - - 2014
The application of physiologically-based toxicokinetic (PBTK) modelling in route-to-route (RtR) extrapolation of three cosmetic ingredients, coumarin, hydroquinone and caffeine is shown in this study. In particular, the oral no-observed-effect-level (NOEL) doses of these chemicals are extrapolated to their corresponding dermal values by comparing the internal concentrations resulting from oral and ...
Dai Ziwei Z Center for Quantitative Biology, Peking University, Beijing 100871, - - 2014
Ordinary differential equations (ODEs) are widely used to model the dynamic properties of biological networks. Due to the complexity of biological networks and limited quantitative experimental data available, estimating kinetic parameters for these models remains challenging. We present a novel global optimization algorithm, differential simulated annealing (DSA), for estimating kinetic ...
Tarko Laszlo - - 2014
The present work employs 152 benzene-carboxylic acid' esters having computed the toxicity within the range [2.251, 10.222] for fathead minnow fish (Pimephales promelas). Calibration set includes many pairs having very similar chemical structure, size, shape and hydrophilicity, but very different value of ECOSAR toxicity or vice versa. The QSTR study, ...
Kazemi Baharan B Department of Zoology, Stockholm University, 10691 Stockholm, Sweden. Electronic address: - - 2014
The theory of mimicry explains how a mimic species gains advantage by resembling a model species [1-3]. Selection for increased mimic-model similarity should then result in accurate mimicry, yet there are many surprising examples of poor mimicry in the natural world [4-8]. The existence of imperfect mimics remains a major ...
van Ruymbeke E E Bio and Soft Matter, Institute on Condensed Matter and Nano-science, Université catholique de Louvain, Louvain-la-Neuve 1348, Belgium. - - 2014
An emerging challenge in polymer physics is the quantitative understanding of the influence of a macromolecular architecture (i.e., branching) on the rheological response of entangled complex polymers. Recent investigations of the rheology of well-defined architecturally complex polymers have determined the composition in the molecular structure and identified the role of ...
Stephan Elena - - 2014
In light of its role in maintaining psychological equanimity, we proposed that nostalgia-a self-relevant, social, and predominantly positive emotion-regulates avoidance and approach motivation. We advanced a model in which (a) avoidance motivation triggers nostalgia and (b) nostalgia, in turn, increases approach motivation. As a result, nostalgia counteracts the negative impact ...
Guthrie J Peter JP Department of Chemistry, University of Western Ontario, London, ON, N6A 5B7, Canada, - - 2014
For the fifth time I have provided a set of solvation energies (1 M gas to 1 M aqueous) for a SAMPL challenge. In this set there are 23 blind compounds and 30 supplementary compounds of related structure to one of the blind sets, but for which the solvation energy is readily ...
Jorge-Peñas A A a Tissue Engineering and Biomaterials Unit, CEIT and TECNUN, University of Navarra , San Sebastian , - - 2014
Traction force microscopy (TFM) is commonly used to estimate cells' traction forces from the deformation that they cause on their substrate. The accuracy of TFM highly depends on the computational methods used to measure the deformation of the substrate and estimate the forces, and also on the specifics of the ...
Dilipkumar M - - 2014
Pressmud, a by-product from the sugarcane industry, was used as a carbon source for the production of inulinase in solid-state fermentation (SSF). Statistical experimental designs were employed to screen the nutrients and optimize the media composition for the production of inulinase by Kluyveromyces marxianus var. marxianus. Eighteen various nutrients were ...
Katan Claudine C CNRS, Institut des Sciences Chimiques de Rennes, UMR6226-CNRS-Université de Rennes 1, 35042 Rennes Cedex, France. - - 2014
In the continuous quest for improving TD-DFT methodologies as a tool to predict the photophysical features of solvated chromophores, we investigate two model regioisomers based on the 1,2,3-triazole moiety. Starting from their experimental absorption and emission spectra, key energy differences highlighting the main trends between the two isomers are extracted ...
Galizia C Giovanni CG University of Konstanz, 78457, Konstanz, - - 2014
Much progress has been made recently in understanding how olfactory coding works in insect brains. Here, I propose a wiring diagram for the major steps from the first processing network (the antennal lobe) to behavioral readout. I argue that the sequence of lateral inhibition in the antennal lobe, non-linear synapses, ...
Yourganov Grigori G Department of Psychology, University of South Carolina, Columbia, SC, USA. Electronic address: - - 2014
The field of fMRI data analysis is rapidly growing in sophistication, particularly in the domain of multivariate pattern classification. However, the interaction between the properties of the analytical model and the parameters of the BOLD signal (e.g. signal magnitude, temporal variance and functional connectivity) is still an open problem. We ...
Ignatova Irina I Department of Physics, University of Oulu, Oulu, - - 2014
Shannon's seminal approach to estimating information capacity is widely used to quantify information processing by biological systems. However, the Shannon information theory, which is based on power spectrum estimation, necessarily contains two sources of error: time delay bias error and random error. These errors are particularly important for systems with ...
Hart Bert A 't BA Biomedical Primate Research Centre, Department Immunobiology, Rijswijk, The Netherlands; University of Groningen, Dept. Neuroscience, University Medical Center, Groningen, The Netherlands; MS Center ErasMS, Rotterdam, The Netherlands. Electronic address: - - 2014
The poor translational validity of autoimmune-mediated inflammatory disease models (AIMID) in inbred and specific pathogen-free (SPF) rodents underlies the high attrition of new treatments for the corresponding human disease. Experimental autoimmune encephalomyelitis (EAE) is a frequently used preclinical AIMID model. We discuss here how crucial information needed for the innovation ...
Gatto M P MP Inail - Department of Occupational Hygiene, Monteporzio Catone, Rome, Italy. Electronic address: - - 2014
Several pesticides are supposed to be neurotoxic for humans, consequently, they may also affect the auditory system. This review analyzes human and experimental animal studies testing the hypothesis that exposure to pesticides is associated with hearing loss. The literature on this topic is still sparse and methodological limitations of some ...
Carstensen Edwin L EL Department of Electrical and Computer Engineering and Department of Biomedical Engineering, University of Rochester, Rochester, New York, USA. Electronic address: - - 2014
This review considers three general classes of physical as opposed to phenomenological models of the shear elasticity of tissues. The first is simple viscoelasticity. This model has a special role in elastography because it is the language in which experimental and clinical data are communicated. The second class of models ...
van Ingen Hugo H NMR Spectroscopy Research Group, Bijvoet Center for Biomolecular Research, Utrecht University, Faculty of Science - Chemistry, Padulaan 8, 3854 CH Utrecht, The Netherlands. Electronic address: - - 2014
Availability of high-resolution atomic structures is one of the prerequisites for a mechanistic understanding of biomolecular function. This atomic information can, however, be difficult to acquire for interesting systems such as high molecular weight and multi-subunit complexes. For these, low-resolution and/or sparse data from a variety of sources including NMR ...
Navarro Arcadi A Institute of Evolutionary Biology (Universitat Pompeu Fabra-CSIC), PRBB, Doctor Aiguader 88, Barcelona, 08003, Catalonia, Spain; Centre de Regulació Genòmica (CRG), Barcelona, Spain; National Institute for Bioinformatics (INB), Barcelona, Spain; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, - - 2014
The early period of genetics is closely associated with the study of chromosomal inversions. For almost a century, evolutionary biologists found evidence for the role of inversions in central processes such as adaptation and speciation. In spite of huge efforts, many questions remain about the evolutionary forces underlying the distribution ...
Balakhnina Irina A IA Lomonosov Moscow State University, Physics Department and International Laser Center, Moscow, 119991 - - 2014
Diagnostic methods and historical document and artwork (in particular, paper items) analysis using modern physical methods is a topical practical problem. Paper materials exhibit nonuniform degradation with the formation of foxing stains. Correct physicochemical identification of the structure of foxed fragments depends on the efficiency of the experimental technique and ...
Trueblood Jennifer S JS Department of Psychology, University of - - 2014
Context effects occur when a choice between 2 options is altered by adding a 3rd alternative. Three major context effects-similarity, compromise, and attraction-have wide-ranging implications across applied and theoretical domains, and have driven the development of new dynamic models of multiattribute and multialternative choice. We propose the multiattribute linear ballistic ...
Ghosh M M - - 2014
A coupled molecular dynamics (MD)-stochastic simulation based model has been proposed here for the thermal conductivity of ethylene glycol (EG) based copper nanofluid. The model is based on the thermal evolution of the nanoparticles dispersed in the nanofluid which is in contact with a heat source. It is natural that ...
Perry-Smith Jill E - - 2014
Social network research emphasizes the access to nonredundant knowledge content that network ties provide. I suggest that some content is more beneficial than others and that tie strength may affect creativity for reasons other than the associated structure. That is, tie strength may affect how individuals process nonredundant knowledge. I ...
Liu Baoshun B State Key Laboratory of Silicate Materials for Architectures, Wuhan University of Technology, Luoshi road 122, Wuhan, Hubei, P. R. China. - - 2014
Since the report of the Honda-Fujishima effect, heterogeneous photocatalysis has attracted much attention around the world because of its potential energy and environmental applications. Although great progresses have been made in recent years, most were focused on preparing highly-active photocatalysts and investigating visible light utilization. In fact, we are still ...
Henschel Henning H Division of Atmospheric Sciences, Department of Physics, University of Helsinki , P.O. Box 64, 00014 Helsinki, - - 2014
Formation of new particles through clustering of molecules from condensable vapors is a significant source for atmospheric aerosols. The smallest clusters formed in the very first steps of the condensation process are, however, not directly observable by experimental means. We present here a comprehensive series of electronic structure calculations on ...
Xu Pengcheng - - 2014
Based on micro-gravimetric sensing data, an analytical modeling method is proposed for comprehensive evaluation and optimization of gas sensing or adsorbing related functional materials. Resonant micro-cantilever is loaded with the material to be evaluated for gravimetric sensing experiment. With sensing isotherm curves obtained at different temperatures, key thermodynamic and kinetic ...
Chaka Anne M - - 2014
An ab initio thermodynamic framework for predicting properties of hydrated magnesium carbonate minerals has been developed using density-functional theory linked to macroscopic thermodynamics through the experimental chemical potentials for MgO, water, and CO2. Including semiempirical dispersion via the Grimme method and small corrections to the generalized gradient approximation of Perdew, ...
Macleod Miles M TINT Centre of Excellence in the Philosophy of the Social Sciences, University of Helsinki, Helsinki, - - 2014
In this paper, we provide a novel analysis of the affordances and trade-offs of different strategies for integrating model-building and experimentation in integrative systems biology. Unimodal strategies rely on collaboration between experimenters and modelers in distinct laboratories. In a bimodal strategy modelers perform their own experiments. Each option has advantages ...
Shen Yi Y Department of Cognitive Sciences, University of California, 3151 Social Sciences Plaza, Irvine, CA, 92697-5100, USA, - - 2014
A MATLAB toolbox for the efficient estimation of the threshold, slope, and lapse rate of the psychometric function is described. The toolbox enables the efficient implementation of the updated maximum-likelihood (UML) procedure. The toolbox uses an object-oriented architecture for organizing the experimental variables and computational algorithms, which provides experimenters with ...
Makinson James C JC University of Sydney, - - 2014
During reproductive swarming honey bee scouts perform two very important functions. Firstly, they find new nesting locations and return to the swarm cluster to communicate their discoveries. Secondly, once the swarm is ready to depart informed scout bees act as guides, leading the swarm to its final destination. We have ...
López-Rubio Ezequiel E Department of Computer Science, University of Malaga, 29071, - - 2014
Growing hierarchical self-organizing models are characterized by the flexibility of their structure, which can easily accomodate for complex input datasets. However, most proposals use the Euclidean distance as the only error measure. Here we propose a way to introduce Bregman divergences in these models, which is based on stochastic approximation ...
Armon Shahaf S The Racah Institute of Physics, The Hebrew University of Jerusalem, Israel. - - 2014
We provide a geometric-mechanical model for calculating equilibrium configurations of chemical systems that self-assemble into chiral ribbon structures. The model is based on incompatible elasticity and uses dimensionless parameters to determine the equilibrium configurations. As such, it provides universal curves for the shape and energy of self-assembled ribbons. We provide ...
Aarts Emmeke E Section Functional Genomics, Center for Neurogenomics and Cognitive Research, VU University Amsterdam, Amsterdam, The - - 2014
In neuroscience, experimental designs in which multiple observations are collected from a single research object (for example, multiple neurons from one animal) are common: 53% of 314 reviewed papers from five renowned journals included this type of data. These so-called 'nested designs' yield data that cannot be considered to be ...
Vera-Licona Paola - - 2014
The inference of gene regulatory networks (GRNs) from system-level experimental observations is at the heart of systems biology, due to its importance for gaining insight into the complex regulatory mechanisms in cellular systems. This includes the inference of both the network topology and its dynamics. While there are many algorithms ...
Hooijmans Carlijn R - - 2014
Systematic Reviews (SRs) of experimental animal studies are not yet common practice, but awareness of the merits of conducting such SRs is steadily increasing. As animal intervention studies differ from randomized clinical trials (RCT) in many aspects, the methodology for SRs of clinical trials needs to be adapted and optimized ...
Zhang Yang Y Department of Chemical Engineering, Michigan Technological University, Houghton, MI, - - 2014
We develop a novel and general modeling framework for enzymatic hydrolysis of cellulose and hemicellulose simultaneously. Our mechanistic model, for the first time, takes into consideration explicitly the time evolution of morphologies of intertwining cellulose and hemicelluloses within substrate during enzymatic hydrolysis. This morphology evolution is driven by hydrolytic chain ...
Masso Majid M Laboratory for Structural Bioinformatics, School of Systems Biology, George Mason University, 10900 University Boulevard MS 5B3, Manassas, VA 20110, USA. Electronic address: - - 2014
The enzyme integrase (IN) of human immunodeficiency virus type 1 (HIV-1) mediates integration of reverse transcribed viral DNA into the human genome, an essential step in the HIV-1 replication cycle. Elvitegravir (EVG) is an HIV-1 strand transfer inhibitor that binds IN and is the second drug in its class to ...
Oubbati Mohamed M Institute of Neural Information Processing, Ulm University, - - 2014
The new tendency of artificial intelligence suggests that intelligence must be seen as a result of the interaction between brains, bodies and environments. This view implies that designing sophisticated behaviour requires a primary focus on how agents are functionally coupled to their environments. Under this perspective, we present early results ...
Payet E E 1Department of Orthopaedic and Traumatologic Surgery, Rouen University Hospital, Rouen, - - 2014
Dorsal capsulodesis is an important part of the treatment of pre-arthritic scapholunate instability. We designed an experimental study using 14 fresh-frozen cadaver wrists to demonstrate the efficacy of a new horizontal dorsal intercarpal capsulodesis. We sectioned the scapholunate ligament to create a scapholunate dislocation. Several radiographic views, static and 'in ...
Lasmar Nour-Eddine - - 2014
In the framework of texture image retrieval, a new family of stochastic multivariate modeling is proposed based on Gaussian Copula and wavelet decompositions. We take advantage of the copula paradigm which makes it possible to separate dependency structure from marginal behavior. We introduce two new multivariate models using respectively generalized ...
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