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Hutchinson Ian B IB Department of Physics and Astronomy, Space Research Centre, University of Leicester, Leicester LE1 7RH, UK - - 2014
The first Raman spectrometers to be used for in situ analysis of planetary material will be launched as part of powerful, rover-based analytical laboratories within the next 6 years. There are a number of significant challenges associated with building spectrometers for space applications, including limited volume, power and mass budgets, ...
Svob Sienna S Department of Geography, McGill University, Burnside Hall Building, H3A 0B9 Montreal, QC - - 2014
The high spatio-temporal variability of aboveground biomass (AGB) in tropical forests is a large source of uncertainty in forest carbon stock estimation. Due to their spatial distribution and sampling intensity, pre-felling inventories are a potential source of ground level data that could help reduce this uncertainty at larger spatial scales. ...
Resnik Linda L Providence VA Medical Center , Providence, RI , USA - - 2014
Abstract Purpose: This case study compares the impact of two prosthetic socket designs, a "traditional" transhumeral (TH) socket design and a Compression Released Stabilized (CRS) socket. Methods: A CRS socket was compared to the existing socket of two persons with transhumeral amputation. Comparisons included assessments of patient comfort and satisfaction ...
Protopapas Athanassios A University of Athens, Greece - - 2014
The concept of Matthew effects in reading development refers to a longitudinally widening gap between high achievers and low achievers. Various statistical approaches have been proposed to examine this idea. However, little attention has been paid to psychometric issues of scaling. Specifically, interval-level data are required to compare performance differences ...
Baggio Giosuè G Brain and Language Laboratory, Neuroscience Area, SISSA International School for Advanced Studies; Language Acquisition and Language Processing Lab, Department of Language and Literature, Norwegian University of Science and - - 2014
We sketch four applications of Marr's levels-of-analysis methodology to the relations between logic and experimental data in the cognitive neuroscience of language and reasoning. The first part of the paper illustrates the explanatory power of computational level theories based on logic. We show that a Bayesian treatment of the suppression ...
Hahn Andrea A 1Division of Infectious Disease, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA 2Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA 3Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA 4Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, - - 2014
Vancomycin is often required to treat serious infections in children, including methicillin resistant Staphylococcus aureus (MRSA) infections. The pharmacodynamic index that best predicts efficacy with vancomycin use for MRSA infection in adults is the 24 hour area under the curve over the minimum inhibitory concentration (AUC/MIC). While multiple pediatric population ...
Prieto Gajardo Carlos C Acoustic Laboratory, Department of Applied Physics, Polytechnic School, University of Extremadura, Avda. de la Univ. s/n, 10003, Caceres, - - 2015
In this paper, the stabilisation times for all 24 h of the day are analysed for 12 measurement stations located in the Spanish town of Malaga and throughout 5 years (2007-2011) of sampling environmental noise levels. For the results to be generalised to sound level measurements made in other streets or cities ...
van der Beek Feddo B FB Department of Otolaryngology, Leiden University Medical Center, Leiden, The - - 2014
Objectives: This study analyzed the predictability of fitting levels for cochlear implant recipients based on a review of the clinical levels of the recipients. Design: Data containing threshold levels (T-levels) and maximum comfort levels (M-levels) for 151 adult subjects using a CII/HiRes 90K cochlear implant with a HiFocus 1/1 J ...
Phillips B L BL Department of Zoology, University of Melbourne, Melbourne, Vic., Australia; School of Marine and Tropical Biology, James Cook University, Townsville, Qld, - - 2014
The two foremost hypotheses on the evolutionary constraints on an organism's thermal sensitivity - the hotter-is-better expectation, and the specialist-generalist trade-off - have received mixed support from empirical studies testing for their existence. Could these conflicting results reflect confusion regarding the organizational level (i.e. species > population > individual) at which these constraints should ...
Veselinović Jovana B JB Faculty of Medicine, Department of Chemistry, University of Niš, Niš, - - 2014
The binding of penicillins to human serum proteins was modeled with optimal descriptors based on the Simplified Molecular Input-Line Entry System (SMILES). The concentrations of protein-bound drug for 87 penicillins expressed as percentage of the total plasma concentration were used as experimental data. The Monte Carlo method was used as ...
Reed Robert M RM Division of Pulmonary and Critical Care Medicine, University of Maryland School of Medicine, 110 South Paca Street, 2nd Floor, Baltimore, MD, 21201, USA, - - 2014
Pleural fluid is typically drawn directly from the pleural space for diagnostic studies, but occasionally analyses are desired when a chest tube is already in place and a traditional approach is not feasible. The diagnostic value of analyzing fluid samples obtained from the pleural fluid collection system after chest tube ...
Balasubramani Sree Ganesh SG School of Chemistry, Indian Institute of Science Education and Research Thiruvananthapuram (IISER-TVM), Kerala 695016, - - 2014
The energetics for the interaction of the noble gas atoms with the carbon nanotubes (CNTs) are investigated using an analytical model and density functional theory calculations. Encapsulation of the noble gas atoms, He, Ne, Ar, Kr, and Xe into CNTs of various chiralities is studied in detail using an analytical ...
He Liang L Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, - - 2014
Next-generation sequencing (NGS) has led to the study of rare genetic variants, which possibly explain the missing heritability for complex diseases. Most existing methods for rare variant (RV) association detection do not account for the common presence of sequencing errors in NGS data. The errors can largely affect the power ...
Mayo Tom T IANC, School of Informatics, University of Edinburgh, 10 Crichton Street, Edinburgh EH8 9AB, - - 2014
DNA methylation is an intensely studied epigenetic mark implicated in many biological processes of direct clinical relevance. While sequencing based technologies are increasingly allowing high resolution measurements of DNA methylation, statistical modelling of such data is still challenging. In particular, statistical identification of differentially methylated regions (DMRs) across different conditions ...
Loitfelder Marisa M Medical University of Graz, Department of Neurology , Auenbruggerplatz 22 , Graz, Styria, Austria , 8036 ; - - 2014
Continuous resting state (RS) fMRI has become particularly useful to identify changes in functional connectivity (FC) in CNS disorders. Fair et al. proposed a method of volume extraction to emulate RS fMRI from block-design experiments. Whether the validity of this approach holds true in Multiple Sclerosis (MS) patients has not ...
Mytilinaios I I Applied Microbiology, School of Applied Sciences, Cranfield University, Cranfield, MK43 0AL, - - 2014
To explore the predictions of a novel rearrangement of the Baranyi-Roberts model (BRM) with time to detection data obtained from optical density data of microbial growth. Growth of E. coli and S. Typhimurium under mild conditions of temperature (25 to 37°C), salt (0.086, 0.51 and 1.03 mol l(-1) ) and ...
Knage-Rasmussen K M KM 1Department of Animal Science,Aarhus University,Blichers Allé 20,PO Box 50 - - 2014
This paper aims to contribute to the development of a cost-effective alternative to expensive on-farm animal-based welfare assessment systems. The objective of the study was to design an animal welfare index based on central database information (DBWI), and to validate it against an animal welfare index based on-farm animal-based measurements ...
Ząbczyk Michał M aInstitute of Cardiology, Jagiellonian University, Medical College and John Paul II Hospital bDepartment of Automatics and Biomedical Engineering, AGH University of Science and Technology, Kraków, - - 2014
The fibrin clot permeability coefficient (Ks) is a useful measure of porosity of the fibrin network, which is determined by a number of genetic and environmental factors. Currently available methods to evaluate Ks are time-consuming, require constant supervision and provide only one parameter. We present an automated method in which ...
Dworkin Emily R ER University of Illinois at Urbana-Champaign, USA - - 2014
Secondary traumatic stress (STS) is an issue of significant concern among providers who work with survivors of sexual assault. Although STS has been studied in relation to individual-level characteristics of a variety of types of trauma responders, less research has focused specifically on rape crisis centers as environments that might ...
Zhao Xi X Department of Chemistry and Pharmacy, Zhuhai College of Jilin University, Zhuhai, - - 2014
To optimize the preparation factors for argan oil microcapsule using complex coacervation of chitosan cross-linked with gelatin based on hybrid-level orthogonal array design via SPSS modeling. Eight relatively significant factors were firstly investigated and selected as calculative factors for the orthogonal array design from the total of ten factors effecting ...
Ruths Justin J Engineering Systems and Design, Singapore University of Technology and Design, Singapore. - - 2014
Campbell, Shea, and Albert propose an adaptation of the Barabási-Albert model of network formation that permits a level of tuning of the control profiles of these networks. We point out some limitations and generalizations of this method as well as highlight opportunities for future work to refine formation mechanisms to ...
Alzghoul Ahmad - - 2014
Glass transition temperature (Tg) is an important inherent property of an amorphous solid material which is usually determined experimentally. In this study, the relation between Tg and melting temperature (Tm) was evaluated using a dataset of 71 structurally diverse drug-like compounds. Further, in silico models for prediction of Tg were ...
Taylor Ryan R Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT - - 2014
Modern lipidomics is largely dependent upon structural ontologies because of the great diversity exhibited in the lipidome, but no automated lipid classification exists to facilitate this partitioning. The size of the putative lipidome far exceeds the number currently classified, despite a decade of work. Automated classification would benefit ongoing classification ...
Klimov Denis D Department of Information Systems Engineering, Faculty of Engineering Sciences, Ben-Gurion University of the Negev, Beer-Sheva, - - 2014
To analyze the longitudinal data of multiple patients and to discover new temporal knowledge, we designed and developed the Visual Temporal Analysis Laboratory (ViTA-Lab). In this study, we demonstrate several of the capabilities of the ViTA-Lab framework through the exploration of renal-damage risk factors in patients with diabetes type II. ...
Brunyé Tad T - - 2014
Human observers are often relied upon for monitoring suspicious crowd behavior in both civilian and military contexts. However, little research has examined what individual- and crowd-level variables independently and interactively modulate threat perception among human observers. Five experiments gathered threat estimates while participants viewed static or dynamic crowd simulations. Experiments ...
Menor Mark - - 2014
MiRNAs play important roles in many diseases including cancers. However computational prediction of miRNA target genes is challenging and the accuracies of existing methods remain poor. We report mirMark, a new machine learning-based method of miRNA target prediction at the site- and UTR-levels. This method uses experimentally verified miRNA targets ...
Hemming Karla K Department of Public Health, Epidemiology and Biostatistics, University of Birmingham, - - 2014
Stepped-wedge cluster randomised trials (SW-CRTs) are being used with increasing frequency in health service evaluation. Conventionally, these studies are cross-sectional in design with equally spaced steps, with an equal number of clusters randomised at each step and data collected at each and every step. Here we introduce several variations on ...
O' Donoghue Deirdre D Central Remedial Clinic, Clondalkin, Dublin, - - 2014
The activPAL™ activity monitor has potential for use in youth with Cerebral Palsy (CP) as it has demonstrated acceptable validity for the assessment of sedentary and physical activity in other populations. This study determined the validity of the activPAL™ activity monitor for the measurement of sitting, standing, walking time, transitions ...
Meeusen Jeffrey W JW Division of Clinical Core Laboratory Services, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, - - 2014
Aggressive LDL cholesterol (LDL-C)-lowering strategies are recommended for primary and secondary prevention of cardiovascular events. A newly derived equation for LDL-C estimation was recently published that addressed limitations in the commonly used Friedewald LDL-C calculation method. The novel method was reported to classify patients with superior concordance to measured LDL-C ...
Wang Xiao-Gang XG Chemistry Department, Queen's University, Kingston, Ontario K7L 3N6, - - 2014
We obtain an accurate methane potential energy surface (PES) by starting with the ab initio PES of Schwenke and Partridge [Spectrochim. Acta A 57, 887 (2001)] and adjusting 5 of their parameters to reproduce 40 reliable experimentally determined vibrational levels of CH4. The 40 levels include all 35 levels in ...
Rowlands Alex V AV a School of Health Sciences , University of South Australia, City East Campus , Adelaide 5001 , - - 2014
Abstract Tudor-Locke and colleagues previously assessed steps/day for 1 year. The aim of this study was to use this data set to introduce a novel approach for the investigation of whether individual's physical activity exhibits periodicity fluctuating round a mean and, if so, the degree of fluctuation and whether the ...
Marković Vladimir M VM Faculty of Physical Chemistry, University of Belgrade, Studentski trg 12-16, 11000 Belgrade, Serbia - - 2014
A mathematical model of the hypothalamic-pituitary-adrenal (HPA) axis with cholesterol as a dynamical variable was derived to investigate the effects of cholesterol, the primary precursor of all steroid hormones, on the ultradian and circadian HPA axis activity. To develop the model, the parameter space was systematically examined by stoichiometric network ...
Wagner Peter J PJ Department of Paleobiology, National Museum of Natural History, Washington, DC 20013; and - - 2014
Evolution provides many cases of apparent shifts in diversification associated with particular anatomical traits. Three general models connect these patterns to anatomical evolution: (i) elevated net extinction of taxa bearing particular traits, (ii) elevated net speciation of taxa bearing particular traits, and (iii) elevated evolvability expanding the range of anatomies ...
Li Meng - - 2014
BackgroundThe inheritance of most human diseases and agriculturally important traits is controlled by many genes with small effects. Identifying these genes, while simultaneously controlling false positives, is challenging. Among available statistical methods, the mixed linear model (MLM) has been the most flexible and powerful for controlling population structure and individual ...
Chu Yi Y Department of Periodontology, School and Hospital of Stomatology, Peking University, Beijing, - - 2014
Background Partial-mouth periodontal examination (PMPE) has been widely used in periodontal epidemiological studies. In this study, we evaluated the accuracy of extent and severity estimates from PMPE protocols in a Chinese population. Methods We enrolled 200 individuals with periodontitis, aged 22 to 64 years. Full-mouth examination was performed to determine ...
Salgado Jorge David JD The Ohio State University, Plant Pathology, Wooster, Ohio, United States ; - - 2014
Fusarium head blight (FHB), caused by the fungus Fusarium graminearum, is known to negatively affect wheat grain yield (YLD) and test weight (TW). However, very little emphasis has been placed on formally quantifying FHB/YLD and FHB/TW relationships. Field plots of three soft red winter wheat cultivars, Cooper (susceptible to FHB), ...
Sudharsan Bharath B WellDoc, Inc, Baltimore, MD, - - 2014
Minimizing the occurrence of hypoglycemia in patients with type 2 diabetes is a challenging task since these patients typically check only 1 to 2 self-monitored blood glucose (SMBG) readings per day. We trained a probabilistic model using machine learning algorithms and SMBG values from real patients. Hypoglycemia was defined as ...
Darwiche Joëlle J Institute of Psychology, Faculty of Social and Political Sciences, University of Lausanne, Lausanne, - - 2014
This paper examines the application of the guidelines for evidence-based treatments in family therapy developed by Sexton and collaborators to a set of treatment models. These guidelines classify the models using criteria that take into account the distinctive features of couple and family treatments. A two-step approach was taken: (1) ...
Schulte Stefanie S Department of Exercise and Sport Science, University of Utah, Salt Lake - - 2014
Objective : Elevated levels of the astroglial protein S100B have been shown to predict sport-related concussion. However, S100B levels within an athlete can vary depending on the type of physical activity (PA) engaged in and the methodologic approach used to measure it. Thus, appropriate reference values in the diagnosis of ...
Atassi Nazem N From the Neurological Clinical Research Institute (NCRI), Department of Neurology (N.A., J.B., A. Sherman, E.S., J.W., I.K., M.C.), and the Biostatistics Center (A. Shui, D.S.), Massachusetts General Hospital, Boston; and Prize4Life (N.Z., M.L.), Cambridge, MA. - - 2014
To pool data from completed amyotrophic lateral sclerosis (ALS) clinical trials and create an open-access resource that enables greater understanding of the phenotype and biology of ALS. Clinical trials data were pooled from 16 completed phase II/III ALS clinical trials and one observational study. Over 8 million de-identified longitudinally collected ...
Bernabeu Miguel O MO CoMPLEX, University College London, Physics Building, Gower St., London WC1E 6BT, UK Centre for Computational Science, Department of Chemistry, University College London, 20 Gordon St., London WC1H 0AJ, UK - - 2014
There is currently limited understanding of the role played by haemodynamic forces on the processes governing vascular development. One of many obstacles to be overcome is being able to measure those forces, at the required resolution level, on vessels only a few micrometres thick. In this paper, we present an ...
Miller S L SL Āwhina VUCEL Incubator, Victoria University of Wellington Coastal Ecology Laboratory (VUCEL), Victoria University of Wellington, PO Box 600, Wellington 6140, New Zealand; Āwhina Research Team, Victoria University of Wellington, PO Box 600, Wellington 6140, New Zealand. Electronic address: - - 2014
Terrestrial sediments are a significant stressor on coastal ecosystems, with both suspended and deposited sediment having adverse effects on aquatic organisms. However, information on the effect of suspended sediments on fertilization success for urchin species is lacking. Using sediment levels similar to those encountered in situ, a controlled experiment was ...
Donat K K Animal Health Service, Thuringian Animal Diseases - - 2014
SUMMARY Environmental samples are a cost-saving and easy-to-use approach to diagnose paratuberculosis at the herd level. Detailed knowledge concerning its uncertainties in herds with a low prevalence of Mycobacterium avium spp. paratuberculosis (MAP) is required to design sampling strategies in control programmes. This study aimed to calculate a threshold level ...
Rousmaniere Tony G TG a Student Health and Counseling , University of Alaska Fairbanks , Fairbanks , AK , - - 2014
Abstract Objective: Although supervision has long been considered as a means for helping trainees develop competencies in their clinical work, little empirical research has been conducted examining the influence of supervision on client treatment outcomes. Specifically, one might ask whether differences in supervisors can predict/explain whether clients will make a ...
DeCarolis Douglas D DD *Minneapolis Veterans Affairs Health Care System, Minneapolis, Minnesota; †Geriatric Research Education and Clinical Center, Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota; and ‡Department of Psychiatry, University of Minnesota Medical School, Twin Cities, - - 2014
Vancomycin dose selection is challenging in the spinal cord injury (SCI) population because of the difficulty in accurately estimating the renal function. Creatinine-based equations have been shown to be unreliable in this patient population. Adjusted equations designed for patients with SCI have not been well studied. Cystatin C is an ...
Jayanegara Anuraga A Department of Animal Nutrition and Feed Technology, Faculty of Animal Science, Bogor Agricultural University, Bogor 16680, - - 2014
Saponins have been considered as promising natural substances for mitigating methane emissions from ruminants. However, studies reported that addition of saponin-rich sources often arrived at contrasting results, i.e. either it decreased methane or it did not. The aim of the present study was to assess ruminal methane emissions through a ...
Thompson Andrew M AM Network Science and Technology Center, Rensselaer Polytechnic Institute, 110 8th Street, Troy, New York 12180-3590, USA and Department of Mathematics, Rensselaer Polytechnic Institute, 110 8th Street, Troy, New York 12180-3590, - - 2014
Agent-based models of the binary naming game are generalized here to represent a family of models parameterized by the introduction of two continuous parameters. These parameters define varying listener-speaker interactions on the individual level with one parameter controlling the speaker and the other controlling the listener of each interaction. The ...
Pei Xiaobing - - 2014
In this paper, a novel label propagation (LP) method is presented, called the manifold adaptive label propagation (MALP) method, which is to extend original LP by integrating sparse representation constraint into regularization framework of LP method. Similar to most LP, first of all, MALP also finds graph edges from given ...
Fan Jianglin J Department of Molecular Pathology, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi, Yamanashi, Shimokato 1110, Chuo-City 409-3898, Japan. Electronic address: - - 2014
Laboratory animal models play an important role in the study of human diseases. Using appropriate animals is critical not only for basic research but also for the development of therapeutics and diagnostic tools. Rabbits are widely used for the study of human atherosclerosis. Because rabbits have a unique feature of ...
Tamisiea Mark E ME National Oceanography Centre, Joseph Proudman Building, 6 Brownlow Street, Liverpool L3 5DA, UK - - 2014
The practical need to understand sea level along the coasts, such as for safe navigation given the spatially variable tides, has resulted in tide gauge observations having the distinction of being some of the longest instrumental ocean records. Archives of these records, along with geological constraints, have allowed us to ...
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