Search Results
Results 101 - 150 of 5764
1 2 3 4 5 6 7 8 9 10 >
Inoue Kentaro K Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, Iizuka, Fukuoka, 820-8502, - - 2014
Mathematical modeling has become a standard technique to understand the dynamics of complex biochemical systems. To promote the modeling, we had developed the CADLIVE dynamic simulator that automatically converted a biochemical map into its associated mathematical model, simulated its dynamic behaviors and analyzed its robustness. To enhance the feasibility by ...
Eriksson Anders A Evolutionary Ecology Group, Department of Zoology, University of Cambridge, Downing Street, Cambridge, CB2 3EJ, - - 2014
Distinguishing between hybridisation and population structure in the ancestral species is a key challenge in our understanding of how permeable species boundaries are to gene flow. The doubly-conditioned frequency spectrum (dcfs) has been argued to be a powerful metric to discriminate between these two explanations, and it was used to ...
Jenkins Todd M TM Cincinnati Children׳s Hospital Medical Center, 3333 Burnet Avenue, MLC 7000, Cincinnati, OH 45229-3039, USA. Electronic address: - - 2014
Utilizing electronic data capture (EDC) systems in data collection and management allows automated validation programs to preemptively identify and correct data errors. For our multi-center, prospective study we chose to use TeleForm, a paper-based data capture software that uses recognition technology to create case report forms (CRFs) with similar functionality ...
Svensson Elin M EM Department of Pharmaceutical Biosciences, Uppsala University, P.O. Box 591, 751 24, Uppsala, Sweden, - - 2014
The objective of this work was to facilitate the development of nonlinear mixed effects models by establishing a diagnostic method for evaluation of stochastic model components. The random effects investigated were between subject, between occasion and residual variability. The method was based on a first-order conditional estimates linear approximation and ...
Amaku Marcos M School of Veterinary Medicine, University of São Paulo, Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo, SP, 05508-270, - - 2014
Dengue is considered one of the most important vector-borne infection, affecting almost half of the world population with 50 to 100 million cases every year. In this paper, we present one of the simplest models that can encapsulate all the important variables related to vector control of dengue fever. The ...
Wiedermann Wolfgang W Department of Psychology, University of Vienna, - - 2014
Previous studies have discussed asymmetric interpretations of the Pearson correlation coefficient and have shown that higher moments can be used to decide on the direction of dependence in the bivariate linear regression setting. The current study extends this approach by illustrating that the third moment of regression residuals may also ...
Baldacchino F F UMR 5175, Centre d'Ecologie Fonctionnelle et Evolutive (CEFE), Université Paul-Valéry (UM3), 34199 Montpellier Cedex 5, - - 2014
In France, during the summer, cattle in mountainous pastures can be highly exposed to tabanid bites. The persistent biting behaviour of tabanids not only causes disturbance, but is also responsible for transmitting diseases, such as bovine besnoitiosis. The purpose of this study was to better identify the level of tabanid ...
Lee Kwang Jin KJ Department of Medical System Engineering (DMSE), Gwangju Institute of Science and Technology (GIST), Gwangju, - - 2014
Neuronal and muscular electrical signals contain useful information about the neuromuscular system, with which researchers have been investigating the relationship of various neurological disorders and the neuromuscular system. However, neuromuscular signals can be critically contaminated by cardiac electrical activity (CEA) such as the electrocardiogram (ECG) which confounds data analysis. The ...
Renart Alfonso A Champalimaud Neuroscience Programme, Champalimaud Foundation, Avenida Brasilia, 1400-038 Lisbon, Portugal. Electronic address: - - 2014
Neural activity and behavior in laboratory experiments are surprisingly variable across trials. This variability and its potential causes have been the focus of a spirited debate. Here we review recent research that has shed light on the sources of neural variability and its impact on behavior. We explain how variability ...
Sannino Giovanna G Institute of High Performance Computing and Networking (ICAR), National Research Council of Italy (CNR), Via Pietro Castellino 111, Naples, Italy; University of Naples "Parthenope", Department of Technology, Naples, Italy. Electronic address: - - 2014
Real-time Obstructive Sleep Apnea (OSA) episode detection and monitoring are important for society in terms of an improvement in the health of the general population and of a reduction in mortality and healthcare costs. Currently, to diagnose OSA patients undergo PolySomnoGraphy (PSG), a complicated and invasive test to be performed ...
Oliveira J P JP Estação Litoral da Aguda, Rua Alfredo Dias, Praia da Aguda, 4410-475 Arcozelo/VNG, Portugal; CIMAR/CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental, Universidade do Porto, Rua dos Bragas 289, 4050-123 Porto, Portugal. Electronic address: - - 2014
Littoral areas are subject to severe and increasing pressures resulting from human activities occurring along or next to the coast. In this study, patterns of variability in the structure of rocky intertidal benthic assemblages and in the abundance of individual taxa were compared between locations close to the coastal cities ...
Van Stan John T JT 2nd Department of Geology and Geography, Georgia Southern University, Statesboro, GA, 30640, USA, - - 2014
Many tree species have been shown to funnel substantial rainfall to their stem base as stemflow flux, given a favorable stand structure and storm conditions. As stemflow is a spatially concentrated flux, prior studies have shown its impact on ecohydrological and biogeochemical processes can be significant. Less work has been ...
Gingold Daniel B DB Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, - - 2014
Warm sea surface temperatures (SST) are positively related to incidence of ciguatera fish poisoning (CFP). Increased severe storm frequency may create more habitat for ciguatoxic organisms. While climate change could expand the endemic range of CFP, the relationship between CFP incidence and specific environmental conditions is unknown. Estimate associations between ...
Chorley Adrian A UK Civil Aviation Authority, Aviation House, Gatwick Airport South, West Sussex, RH6 0YR, - - 2014
It is known that ultraviolet radiation (UVR) increases by 10-12% every 1,000 m altitude; UVR at the 10, 000 m of typical cruise altitude for commercial aircraft may be 2-3 times higher than at ground level. Information on the levels of solar UV exposures is essential for the assessment of ...
Jeffrey Kao Ming-Chih MC Stanford Hospital & Clinics, Department of Orthopaedics, Palo Alto, - - 2014
To develop and implement methodologies for characterizing accelerometry-derived patterns of physical activity (PA) in the United States in relation to demographics, anthropometrics, behaviors, and co-morbidities using the NHANES dataset. Retrospective analysis of nationally representative database SETTING: Computer-generated modeling in silico PARTICIPANTS: 6,329 adults in the U.S. from NHANES 2003-2004 database. ...
Ma Xiao-Kui XK Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry, Ministry of Education, National Engineering Laboratory for Resource Developing of Endangered Chinese Crude Drugs in Northwest of China, College of Life Sciences, Shaanxi Normal University, Xi'an 710062, Shaanxi, China. Electronic address: - - 2014
The study was conducted to enhance exopolysaccharide (EPS) antioxidant formation (as measured by Trolox-Equivalent Antioxidant Capacity, TEAC) by Phellinus sp. P0988 through medium studies, while jointly increasing EPS yield. Out of seven medium components, four significant variables were identified based on linear models with statistical significance (p<0.05), namely rutin, FeSO4, ...
Minadakis George G Department of Electronic and Computer Engineering, Brunel University Uxbridge, Middlesex, UB8 3PH, - - 2014
Objective. Recent cross-disciplinary literature suggests a dynamical analogy between earthquakes and epileptic seizures. This study extends the focus of inquiry for the applicability of models for earthquake dynamics to examine both scalp-recorded and intracranial electroencephalogram recordings related to epileptic seizures. Approach. First, we provide an updated definition of the electric ...
Liang Suh-Yuen SY Core Facilities for Protein Structural Analysis at Institute of Biological Chemistry, Academia Sinica, Taipei, - - 2014
Despite many attempts for algorithm development in recent years, automated identification of intact glycopeptides from LC-MS(2) spectral data is still a challenge in both sensitivity and precision. We implemented a supervised machine learning algorithm, Random Forest, in an automated workflow to identify N-glycopeptides using spectral features derived from ion trap-based ...
Chemolli Emanuela - - 2014
Self-determination theory (SDT) proposes a multidimensional conceptualization of motivation in which the different regulations are said to fall along a continuum of self-determination. The continuum has been used as a basis for using a relative autonomy index as a means to create motivational scores. Rasch analysis was used to verify ...
Berends H H Animal Nutrition Group, Wageningen University, P.O. Box 338, 6700 AH Wageningen, The Netherlands. Electronic address: - - 2014
A dynamic, mechanistic model of the sulfur hexafluoride (SF6) tracer technique, used for estimating methane (CH4) emission rates from ruminants, was constructed to evaluate the accuracy of the technique. The model consists of six state variables and six zero-pools representing the quantities of SF6 and CH4 in rumen and hindgut ...
Schmidt J Michael JM Department of Neurology, Columbia University Medical Center, New York, Milstein Hospital Building, 177 Fort Washington Avenue, Suite 8-300, New York, NY, 10032, USA, - - 2014
We sought to determine if monitoring heart rate variability (HRV) would enable preclinical detection of secondary complications after subarachnoid hemorrhage (SAH). We studied 236 SAH patients admitted within the first 48 h of bleed onset, discharged after SAH day 5, and had continuous electrocardiogram records available. The diagnosis and date of ...
Ebeed Mohamed M Deef Pharmaceuticals Inc., Al Badaye, Al Qassim, Saudi Arabia; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Zagazig University, - - 2014
L18 Hunter design was used to investigate the practicability of applying QbD approaches to fluidized hot melt granulation (FHMG) in preparing oral controlled release systems. Eight high-risk variables obtained from risk analysis were classified into chemical factors (type and percentage of meltable binder, matrix viscosity and percentage and filler type) ...
Panouillères M M EA3181, University of Franche-Comte, Besançon, France, - - 2014
The present study investigates the properties of the French version of the OUT-PATSAT35 questionnaire, which evaluates the outpatients' satisfaction with care in oncology using classical analysis (CTT) and item response theory (IRT). This cross-sectional multicenter study includes 692 patients who completed the questionnaire at the end of their ambulatory treatment. ...
Baiocchi Michael M Department of Statistics, Stanford University, Stanford, CA, - - 2014
A goal of many health studies is to determine the causal effect of a treatment or intervention on health outcomes. Often, it is not ethically or practically possible to conduct a perfectly randomized experiment, and instead, an observational study must be used. A major challenge to the validity of observational ...
Hennig Stefanie S Department of Pharmaceutical Bioscience, Uppsala University, Uppsala, Sweden, - - 2014
When performing a population pharmacokinetic modelling analysis covariates are often added to the model. Such additions are often justified by improved goodness of fit and/or decreased in unexplained (random) parameter variability. Increased goodness of fit is most commonly measured by the decrease in the objective function value. Parameter variability can ...
Sacha Jerzy J Department of Cardiology, Regional Medical Center, Opole, - - 2014
Heart rate variability (HRV) is significantly associated with average heart rate (HR), therefore, HRV actually provides information on two quantities, that is, on HR and its variability. It is difficult to conclude which of these two plays a principal role in the HRV clinical value, or in other words, what ...
Suárez Liliana L School of Public Health, Faculty of Medicine, University of Chile, Santiago, - - 2014
The objective of this study was to compare personal exposure to particulate matter (fine and ultrafine particles) in commuters using different transport modes (bicycle, bus, car and subway) in a busy, assigned route in downtown Santiago, Chile. Volunteers carrying personal samplers completed scheduled commutes during the morning rush hours, while ...
Coen Philip P 1] Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey 08544, USA [2] Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, - - 2014
The generation of acoustic communication signals is widespread across the animal kingdom, and males of many species, including Drosophilidae, produce patterned courtship songs to increase their chance of success with a female. For some animals, song structure can vary considerably from one rendition to the next; neural noise within pattern ...
Teske Jennifer A JA University of - - 2014
When exploring biological determinants of spontaneous physical activity (SPA), it is critical to consider whether methodological factors differentially affect rodents and the measured SPA. We determined whether acclimation time, sensory stimulation, vendor or chamber size affected measures in rodents with varying propensity for SPA. We used principal component analysis to ...
Donaldson Finn E FE Division of Physics, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, Office of Medical Products and Tobacco, U.S. Food and Drug Administration, Silver Spring, MD, USA. Electronic address: - - 2014
A variety of design and patient parameters have been implicated in recent reports of fretting corrosion at modular connections in total hip arthroplasty. We sought to identify the relative sensitivity of mechanical fretting to a comprehensive set of parameters such that attention may be focused on key variables. Stochastic finite ...
Guo Gang - - 2014
In this study, a single-trait genomic model (STGM) is compared with a multiple-trait genomic model (MTGM) for genomic prediction using conventional estimated breeding values (EBVs) calculated using a conventional single-trait and multiple-trait linear mixed models as the response variables. Three scenarios with and without missing data were simulated; no missing ...
Chen Hui - - 2014
In this work, the potential of mineral elements and chemometric methods as a tool to classify the Chinese honeys according to their botanical origin was examined. Twelve mineral elements (Na23, Mg24, P31, K39, Ca43, Mn55, Fe56, Cu63, Zn66, Rb85, Sr88 and Ba137) of 163 Chinese honey samples, including linden, chaste, ...
Baker Timothy R TR School of Geography, University of Leeds, Leeds, LS2 9JT, - - 2014
The Amazon rain forest sustains the world's highest tree diversity, but it remains unclear why some clades of trees are hyperdiverse, whereas others are not. Using dated phylogenies, estimates of current species richness and trait and demographic data from a large network of forest plots, we show that fast demographic ...
Leviyang Sivan S Georgetown University, Department of Mathematics and Statistics, United - - 2014
Intrahost human and simian immunodeficiency virus (HIV and SIV) evolution is marked by repeated viral escape from cytotoxic T-lymphocyte (CTL) response. Typically, the first such CTL escape starts around the time of peak viral load and completes within one or two weeks. Many authors have developed methods to quantify CTL ...
Van Goethem Davina D Department of Bio-science Engineering, University of Antwerp, Antwerp, Belgium, - - 2014
In recent years, temperate bamboo species have been introduced in Europe for multiple uses such as renewable bio-based materials (wood, composites, fibres, biochemicals…) and numerous ecological functions (soil and water conservation, erosion control, phytoremediation…). Despite their interesting potential, little is known on the ecophysiology of these plants in their new ...
Davidson Clare Muireann - - 2014
Deep brain stimulation effectively alleviates motor symptoms of medically refractory Parkinson's disease, and also relieves many other treatment-resistant movement and affective disorders. Despite its relative success as a treatment option, the basis of its efficacy remains elusive. In Parkinson's disease, increased functional connectivity and oscillatory activity occur within the basal ...
Orme-Johnson David W DW Institute of Science, Technology and Public Policy, Maharishi University of - - 2014
We commend Sedlmeier et al. (2012) for their significant undertaking of meta-analysis of all meditation types on all psychological variables, but additional analyses may modify some of their conclusions. Whereas they suggest from visual inspection of funnel diagrams that there may be publication bias of underreporting low-effect studies on the ...
Gou Jianwei - - 2014
Evidence suggests that common complex diseases may be partially due to SNP-SNP interactions, but such detection is yet to be fully established in a high-dimensional small-sample (small-n-large-p) study. A number of penalized regression techniques are gaining popularity within the statistical community, and are now being applied to detect interactions. These ...
Marathe Amar R - - 2014
Patterns of neural data obtained from electroencephalography (EEG) can be classified by machine learning techniques to increase human-system performance. In controlled laboratory settings this classification approach works well; however, transitioning these approaches into more dynamic, unconstrained environments will present several significant challenges. One such challenge is an increase in temporal ...
Kollmorgen Sepp S Institute of Neuroinformatics, University of Zurich/ETH Zurich, Zurich, - - 2014
Recently, there have been remarkable advances in modeling the relationships between the sensory environment, neuronal responses, and behavior. However, most models cannot encompass variable stimulus-response relationships such as varying response latencies and state or context dependence of the neural code. Here, we consider response modeling as a dynamic alignment problem ...
Pan Tao T Key Laboratory of Optoelectronic Information and Sensing Technologies of Guangdong Higher Educational Institutes, Jinan University, Guangzhou 510632, - - 2014
Equidistant combination multiple linear regression (EC-MLR) for the quasi-continuous wavelength selection of spectroscopic analysis was proposed and successfully applied to the reagent-free determination of soil organic matter with near-infrared spectroscopy. For comparison, the continuous-mode moving window partial least squares (MWPLS) and the discrete-mode successive projections algorithm (SPA) were improved by ...
Doolette David J DJ Navy Experimental Diving Unit, 321 Bullfinch Road, Panama City, FL 32407, USA, Phone: +1-(0)850-230-3100, E-mail: - - 2014
In studies of decompression procedures, ultrasonically detected venous gas emboli (VGE) are commonly used as a surrogate outcome if decompression sickness (DCS) is unlikely to be observed. There is substantial variability in observed VGE grades, and studies should be designed with sufficient power to detect an important effect. Data for ...
Pouplier Marianne - - 2014
PURPOSE Phonetic accommodation - whether in an error allophonic properties are appropriate to the new environment - has traditionally been used to identify the processing level at which an error has occurred. Recent studies have challenged the view that non-canonical productions may solely be due to phonetic, not phonological processing ...
Eckhard Timo - - 2014
In this work, we evaluate the conditionally positive definite logarithmic kernel in kernel-based estimation of reflectance spectra. Reflectance spectra are estimated from responses of a 12-channel multispectral imaging system. We demonstrate the performance of the logarithmic kernel in comparison with the linear and Gaussian kernel using simulated and measured camera ...
Sheng Zheng Z College of Meteorology and Oceanography, PLA University of Science and Technology, Nanjing 211101, - - 2014
This paper introduces a novel hybrid optimization algorithm to establish the parameters of chaotic systems. In order to deal with the weaknesses of the traditional cuckoo search algorithm, the proposed adaptive cuckoo search with simulated annealing algorithm is presented, which incorporates the adaptive parameters adjusting operation and the simulated annealing ...
Wang Ruofan R Department of Electrical and Automation Engineering, Tianjin University, Tianjin, - - 2014
A combined method composing of the unscented Kalman filter (UKF) and the synchronization-based method is proposed for estimating electrophysiological variables and parameters of a thalamocortical (TC) neuron model, which is commonly used for studying Parkinson's disease for its relay role of connecting the basal ganglia and the cortex. In this ...
Cummins Megan A MA Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of - - 2014
Reverse rate dependence is a problematic property of antiarrhythmic drugs that prolong the cardiac action potential (AP). The prolongation caused by reverse rate dependent agents is greater at slow heart rates, resulting in both reduced arrhythmia suppression at fast rates and increased arrhythmia risk at slow rates. The opposite property, ...
Enders Craig K CK Department of Psychology, Arizona State - - 2014
The existing missing data literature does not provide a clear prescription for estimating interaction effects with missing data, particularly when the interaction involves a pair of continuous variables. In this article, we describe maximum likelihood and multiple imputation procedures for this common analysis problem. We outline 3 latent variable model ...
Fascione Jeanna M JM Foot & Ankle Specialists of Ohio, Inc, Mentor, - - 2014
Background : The use of foot measurements to classify morphology and interpret foot function remains one of the focal concepts of lower-extremity biomechanics. However, only 27% to 55% of midfoot variance in foot pressures has been determined in the most comprehensive models. We investigated whether dynamic walking footprint measurements are ...
Brendel Oliver O INRA, UMR1137 'Ecologie et Ecophysiologie Forestières', F-54280, Champenoux, France; Université de Lorraine, UMR1137 'Ecologie et Ecophysiologie Forestières', Faculté des Sciences, F-54500, Vandoeuvre-Les-Nancy, - - 2014
The isotopic compositions of low-mass elements such as carbon are commonly expressed on the δ scale, relative to the isotopic ratio of an international standard (RST ). Carbon stable isotope measurements of plant material are interpreted with an apparently biological meaning as an estimator of water use efficiency, and this ...
1 2 3 4 5 6 7 8 9 10 >