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Frajka-Williams E E University of Southampton, National Oceanography Centre, Southampton SO14 3ZH, UK - - 2014
Sustained observations of ocean properties reveal a global warming trend and rising sea levels. These changes have been documented by traditional ship-based measurements of ocean properties, whereas more recent Argo profiling floats and satellite records permit estimates of ocean changes on a near real-time basis. Through these and newer methods ...
Spector June T JT 1.Departments of Environmental and Occupational Health Sciences and Medicine, University of Washington, Seattle, WA 98105, USA - - 2014
The potential consequences of occupational heat stress in a changing climate on workers, workplaces, and global economies are substantial. Occupational heat stress risk is projected to become particularly high in middle- and low-income tropical and subtropical regions, where optimal controls may not be readily available. This commentary presents occupational heat ...
Matchin William W Department of Cognitive Sciences, University of California, Irvine, United - - 2014
Accounts of the role of Broca's area in sentence comprehension range from specific syntactic operations to domain-general processes. The present study was designed to tease apart these two general accounts by measuring the BOLD response to two syntactically distinct long-distance dependencies that invoke abstractly similar predictive processes: backward anaphora and ...
Wang Liang L Mathematical Sciences Department, Worcester Polytechnic Institute, Worcester, MA, - - 2014
Atherosclerotic plaque progression is believed to be associated with mechanical stress conditions. Patient follow-up in vivo intravascular ultrasound coronary plaque data were acquired to construct fluid-structure interaction (FSI) models with cyclic bending to obtain flow wall shear stress (WSS), plaque wall stress (PWS) and strain (PWSn) data and investigate correlations ...
Simons Margaret N MN The Pennsylvania State - - 2014
Zea mays L. is an important C4 plant due to its widespread use as a cereal and energy crop. A second-generation genome-scale metabolic model for the maize leaf was created to capture C4 carbon fixation and investigate nitrogen (N) assimilation by modeling the interactions between the bundle sheath and mesophyll ...
Tripathi Vijay V Center of Bioinformatics, IIDS, Faculty of Science, University of Allahabad, Allahabad, - - 2014
Superoxide dismutases are a class of enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. As such, they are an important antioxidant defense in nearly all cells exposed to oxygen. Superoxide dismutase (SOD) acts as first line of defense against oxidative and genetic stress. Manganese superoxide dismutase ...
Rey Patrice F PF Earthbyte Research Group, School of Geosciences, The University of Sydney, Sydney NSW 2006, - - 2014
Stresses acting on cold, thick and negatively buoyant oceanic lithosphere are thought to be crucial to the initiation of subduction and the operation of plate tectonics, which characterizes the present-day geodynamics of the Earth. Because the Earth's interior was hotter in the Archaean eon, the oceanic crust may have been ...
Zhang Xinzhuang X State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process, Kanion Pharmaceutical Corporation, Lianyungang City 222002, P. R. China. - - 2014
In comparison to the current target-based screening approach, it is increasingly evident that active lead compounds based on disease-related phenotypes are more likely to be translated to clinical trials during drug development. That is, because human diseases are in essence the outcome of the abnormal function of multiple genes, especially ...
Wang Lingnan - - 2014
Dietary antioxidants as health promoters for human beings have attracted plentiful attentions and triggered tremendous efforts in evaluation of the antioxidant capacity. Unfortunately, no versatile detection system has been designed to date. Due to the possible synergistic effect among antioxidant components in a diversified system, to isolate and quantify individual ...
Bai Xuelian X Department of Soil Science, North Dakota State University, Fargo, ND 58108-6050, - - 2014
Animal manure is the primary source of exogenous free estrogens in the environment, which are known endocrine-disrupting chemicals to disorder the reproduction system of organisms. Conjugated estrogens can act as precursors to free estrogens, which may increase the total estrogenicity in the environment. In this study, a comprehensive model was ...
Steger Michael F MF Colorado State University; North-West University, Vanderbijlpark, South - - 2014
Posttrauma adjustment theories postulate that intense stressors violate people's beliefs about the world and perceived ability to achieve valued goals. Failure to make meaning from traumatic events exacerbates negative adjustment (e.g., PTSD), whereas success facilitates positive adjustment (e.g., stress-related growth). The current study aimed to test this model of direct ...
Roy Pierre-Olivier PO CIRAIG, Chemical Engineering Department, École Polytechnique de Montréal, P.O. Box 6079, Montréal, Québec, Canada, H3C 3A7. Electronic address: - - 2014
Characterization factors (CFs) are used in life cycle assessment (LCA) to quantify the potential impact per unit of emission. CFs are obtained from a characterization model which assess the environmental mechanisms along the cause-effect chain linking an emission to its potential damage on a given area of protection, such as ...
Santos-Filho Paulo César Freitas PC Department of Restorative Dentistry and Dental Materials, Dentistry School, Federal University of Uberlandia, Minas Gerais, Brazil. Electronic address: - - 2014
The aim of this study was to evaluate the influence of a ferrule, post system, and length on the stress distribution of weakened root-filled teeth. The investigation was conducted by using 3-dimensional (3D) finite element analysis. A sound tooth and 8 3D models of a weakened root-filled central incisor were ...
Patra P K PK 1] Department of Environmental Geochemical Cycle Research, JAMSTEC, Yokohama 236 0001, Japan [2] CAOS, Graduate School of Studies, Tohoku University, Sendai 980 8578, - - 2014
The hydroxyl radical (OH) is a key oxidant involved in the removal of air pollutants and greenhouse gases from the atmosphere. The ratio of Northern Hemispheric to Southern Hemispheric (NH/SH) OH concentration is important for our understanding of emission estimates of atmospheric species such as nitrogen oxides and methane. It ...
Kingsley Laura J LJ Department of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, Indiana, 47907, - - 2014
Predicting atoms in a potential drug compound that are susceptible to oxidation by cytochrome P450 (CYP) enzymes is of great interest to the pharmaceutical community. We aimed to develop a computational approach combining ligand- and structure-based design principles to accurately predict sites of metabolism (SoMs) in a series of CYP2C9 ...
Johnson Jessica K M JK Graduate School of Social Work, Boston College, Chestnut Hill, Massachusetts. - - 2014
Aging successfully entails good physical and cognitive health, as well as ongoing participation in social and productive activity. This study hones in on participation in productive activity, a factor that makes an important contribution to successful aging. One conceptual model of productive activity in later life specifies the antecedents and ...
Börlin Christoph S - - 2014
BackgroundAutophagy is a vesicle-mediated pathway for lysosomal degradation, essential under basal and stressed conditions. Various cellular components, including specific proteins, protein aggregates, organelles and intracellular pathogens, are targets for autophagic degradation. Thereby, autophagy controls numerous vital physiological and pathophysiological functions, including cell signaling, differentiation, turnover of cellular components and pathogen ...
Chen YungChung Y Minnesota Dental Research Center for Biomaterials and Biomechanics, School of Dentistry, University of Minnesota, MN, USA. Electronic address: - - 2014
This study aimed to investigate how the structural stress distribution in human teeth could be affected by the presence of a graded material distribution often found in nature using the finite element (FE) method. Hydroxyapatite (HA) tablets with different densities were scanned using a Micro-CT scanner to obtain a relationship ...
Ikegawa Yusuke Y Graduate School of Science, Osaka Prefecture University, Gakuen-cho 1-1, Naka-ku, Sakai, 599-8531 JAPAN. Electronic address: - - 2014
Intra-guild predation (IGP), predation on consumers which share common prey with the predators, is an important community module to understand a mechanism for persistence of complex food webs. However, classical theory suggests that persistence of an IGP system is unlikely particularly at high productivity, while empirical data do not support ...
Machado Daniel D Centre of Biological Engineering, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal. Electronic address: - - 2014
Curcumin is a natural compound obtained from turmeric, and is well known for its pharmacological effects. In this work, we design a heterologous pathway for industrial production of curcumin in Escherichia coli. A kinetic model of the pathway is then developed and connected to a kinetic model of the central ...
Rahman Tanzina T University of Texas at San Antonio, Department of Civil and Environmental Engineering, One UTSA Circle, San Antonio, TX 78249, - - 2014
Aluminum oxide nanoparticles have been widely used in various consumer products and there are growing concerns regarding their exposure in the environment. This study deals with the modeling, sensitivity analysis and uncertainty quantification of one-dimensional transport of nano-sized (~82nm) aluminum oxide particles in saturated sand. The transport of aluminum oxide ...
Kourdali Sidali S Department of Industrial Chemistry, Faculty of Technology, University of Saàd Dahlab at Blida, PO Box 270, 09000 Blida, Algeria; Laboratory of Natural Substances Chemistry and Biomolecules, University of Saàd Dahlab at Blida, PO Box 270, 09000 Blida, Algeria; National Centre for Research and Development of Fisheries and Aquaculture (CNRDPA) 11, Bd Amirouche PO Box 67, Bousmail (W. Tipaza), Algeria. Electronic address: - - 2014
The present study was undertaken to investigate the degradation and removal of direct yellow 9 (DY9) by the electro-Fenton (EF) process in batch reactor using iron and stainless steel electrodes. DY9 removal decreased with the increase in pH (3 to 8) and increased with the increase in current intensity (0.05 ...
Walter Johannes J Institute of Particle Technology (LFG), Friedrich-Alexander University Erlangen-Nürnberg (FAU), Cauerstr. 4, 91058, Erlangen, - - 2014
In this paper, a method to determine the lateral dimensions of 2D nanosheets directly in suspension by analytical ultracentrifugation (AUC) is shown. The basis for this study is a well-characterized and stable dispersion of graphene oxide (GO) monolayers in water. A methodology is developed to correlate the sedimentation coefficient distribution ...
Kroeger Timm T Central Science Department, Nature Conservancy, Arlington, VA 22203; - - 2014
High ambient ozone (O3) concentrations are a widespread and persistent problem globally. Although studies have documented the role of forests in removing O3 and one of its precursors, nitrogen dioxide (NO2), the cost effectiveness of using peri-urban reforestation for O3 abatement purposes has not been examined. We develop a methodology ...
Wu Li-Ping LP Associate Professor, Department of Orthopedics, Jiangmen Central Hospital of Guangdong Province China (Affiliated Jiangmen Hospital of Sun Yat-Sen University), 529031 Jiangmen, Guangdong, PR China. Electronic address: - - 2014
The objective of this study was to research the distribution of stresses and displacements in cervical nuclei pulposi during simulated cervical spine manipulation (CSM). A 3-dimensional finite element model of C3/4~C6/7 was established. The detailed mechanical parameters of CSM were analyzed and simulated. During the process, the changes in stresses ...
Coe Kirsten K KK Department of Ecology and Evolutionary Biology, Cornell University, Ithaca, NY, 14853, USA, - - 2014
Fluctuations in mean annual precipitation (MAP) will strongly influence the ecology of dryland ecosystems in the future, yet, because individual precipitation events drive growth and resource availability for many dryland organisms, changes in intra-annual precipitation may disproportionately influence future dryland processes. This work examines the hypothesis that intra-annual precipitation changes ...
Wang Yan Y College of Pharmacy, Yaoke University i.e. Shenyang Pharmaceutical University, Shenyang, P.R. China; College of Pharmacy and Chemistry, Dali University, Dali, P.R. - - 2014
A capillary electrophoresis fingerprint was constructed for Sanhuang Tablet of a Chinese traditional patent medicine that was commonly used in clinical practice, where the isosceles trapezoid method was first applied for the optimization of background electrolyte solution, and the resolution index was performed to assess the experimental conditions, furthermore, a ...
Sharma Mukesh C MC Drug Design and Development Laboratory, School of Pharmacy, Devi Ahilya Vishwavidyalaya, Takshila Campus, Khandwa Road, Indore, M.P, 452 001, India, - - 2014
A series of oxadiazole-substituted α-isopropoxy phenylpropanoic acids with dual activators of PPARα and PPARγ derivatives were subjected to two dimensional and k-nearest neighbour Molecular field analysis. The statistically significant best 2D-QSAR (PPARα) model having good predictive ability with statistical values of r(2) = 0.8725, q(2) = 0.7957 and pred_r(2) = ...
Sharma Mukesh C MC Drug Design and Development Laboratory, School of Pharmacy, Devi Ahilya University, Takshila Campus, Khandwa Road, Indore, 452 001, India, - - 2014
The present studies are an attempt in this direction seeking for the development and comparison of QSAR models of substituted 2-aminopyridines derivatives as inhibitors of nitric oxide synthases by different feature selection methods. Comparing the two different feature selection methods, it is implicit that the model built with the selected ...
Caron Troy T Wellspan Orthopedics, York, - - 2014
The decision to leave a job can be very stressful. Multiple variables must be considered before turning in your notice. The goal of this paper is to help you decide if changing jobs is a smart decision, and, if it is, when to do it.
Kocalevent Rüya-Daniela - - 2014
The population-based study examined postulated effects, derived from a resources-demands-model about gender-related aspects of self-efficacy, optimism, chronic stress, and exhaustion. Data acquisition was carried out by a market research institute with a multi-topic questionnaire in the general population (N = 2,552). Instruments administered were the Questionnaire for Self-Efficacy and Optimism, ...
Berre David D LEM-CNRS (UMR 8179) and IÉSEG School of Management, 3 Rue de la Digue, 59000 Lille, France; CIRAD, UMR SELMET, CIRAD-Réunion, Pôle élevage, Ligne Paradis, 97410 St Pierre, La Réunion, France. Electronic address: - - 2014
This study focused on the trade-off between milk production and its environmental impact on greenhouse gas (GHG) emissions and nitrogen surplus in a high input tropical system. We first identified the objectives of the three main stakeholders in the dairy sector (farmers, a milk cooperative and environmentalists). The main aim ...
Devin Simon S Université de Lorraine, CNRS UMR 7360, Laboratoire Interdisciplinaire des Environnements Continentaux (LIEC) - Metz, France. Electronic address: - - 2014
In environmental science, the variability of biological responses in natural or laboratory populations is a well known and documented phenomenon. However, while an extensive literature aims to explain and understand the origin of variability, few try to use it as a demonstration of the population's response facing a stress. We ...
Guo Xin - - 2014
We developed a computer-based first-principles kinetic Monte Carlo (CF-KMC) model to predict degradation mechanisms and fates of intermediates and byproducts produced from the degradation of polyethylene glycol (PEG) in the presence of hydrogen peroxide (UV/H2O2). The CF-KMC model is comprised of a reaction pathway generator, a reaction rate constant estimator, ...
Castro Marcelo A MA Grupo de Investigación y Desarrollo en Bioingeniería, Universidad Tecnológica Nacional, Facultad Regional Buenos Aires, CONICET, Medrano 951, CP 1179, Buenos Aires, Argentina, - - 2014
The aim of this work was to determine whether or not Newtonian rheology assumption in image-based patient-specific computational fluid dynamics (CFD) cerebrovascular models harboring cerebral aneurysms may affect the hemodynamics characteristics, which have been previously associated with aneurysm progression and rupture. Ten patients with cerebral aneurysms with lobulations were considered. ...
Nute Jessica L JL From the Departments of *Imaging Physics, and †Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX; ‡GE Healthcare, Waukesha, WI; Departments of §Biostatistics, and ‚ą•Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, - - 2014
Calcific and hemorrhagic intracranial lesions with attenuation levels of less than 100 Hounsfield units (HUs) cannot currently be reliably differentiated by single-energy computed tomography (SECT). The proper differentiation of these lesion types would have a multitude of clinical applications. A phantom model was used to test the ability of dual-energy ...
Zach Lukáš L Department of Mechanics, Biomechanics and Mechatronics, Faculty of Mechanical Engineering, Czech Technical University in Prague, Technická 4, 166 07 Praha 6, Czech - - 2014
The aim of this paper was to design a finite element model for a hinged PROSPON oncological knee endoprosthesis and to verify the model by comparison with ankle flexion angle using knee-bending experimental data obtained previously. Visible Human Project CT scans were used to create a general lower extremity bones ...
Au Jennifer J Department of Chemical and Biomolecular Engineering, Metabolic Engineering and Systems Biology Laboratory, University of Delaware, 150 Academy Street, Newark, DE 19716, - - 2014
In this work, we provide new insights into the metabolism of Clostridium acetobutylicum ATCC 824 obtained using a systematic approach for quantifying fluxes based on parallel labeling experiments and (13)C-metabolic flux analysis ((13)C-MFA). Here, cells were grown in parallel cultures with [1-(13)C]glucose and [U-(13)C]glucose as tracers and (13)C-MFA was used ...
Maher Marcus A MA Focas Research Institute, Dublin Institute of Technology, Kevin Street, Dublin 8, Ireland. Electronic address: - - 2014
A phenomenological rate equation model is constructed to numerically simulate nanoparticle uptake and subsequent cellular response. Polyamidoamine dendrimers (generations 4-6) are modelled and the temporal evolution of the intracellular cascade of; increased levels of reactive oxygen species, intracellular antioxidant species, caspase activation, mitochondrial membrane potential decay, tumour necrosis factor and ...
Buchwald Peter P University of Miami - - 2014
Analysis of a large number of data on cytochrome P450 inhibition obtained from quantitative high-throughput screening (qHTS) assays from PubChem Bioassays clearly indicates that molecular size has an important activity-limiting role for datasets focused on drug-like compounds (AID 1851) as well as for datasets also incorporating a wider range of ...
Gao Yunjiao Y City University of Hong Kong, Kowloon, Hong - - 2014
Using a sample of 1,163 adolescents from four middle schools in China, this study explores the intervening process of how adolescent maltreatment is related to delinquency within the framework of general strain theory (GST) by comparing two models. The first model is Agnew's integrated model of GST, which examines the ...
Lehahn Yoav Y Department of Earth and Planetary Sciences, Weizmann Institute of Science, Rehovot 76100, - - 2014
Phytoplankton blooms are ephemeral events of exceptionally high primary productivity that regulate the flux of carbon across marine food webs [1-3]. Quantification of bloom turnover [4] is limited by a fundamental difficulty to decouple between physical and biological processes as observed by ocean color satellite data. This limitation hinders the ...
Hembry David H DH Department of Environmental Science, Policy, and Management, University of California, Berkeley, California - - 2014
Abstract Coevolution, reciprocal adaptation between two or more taxa, is commonly invoked as a primary mechanism responsible for generating much of Earth's biodiversity. This conceptually appealing hypothesis is incredibly broad in evolutionary scope, encompassing diverse patterns and processes operating over timescales ranging from microbial generations to geological eras. However, we ...
Quinn Jason C JC Mechanical and Aerospace Engineering, Utah State University, Logan, UT 84341, USA. Electronic address: - - 2014
This study presents experimental measurements of the biochemical methane production for whole and lipid extracted Nannochloropsis salina. Results show whole microalgae produced 430cm(3)-CH4g-volatile solids(-1) (g-VS) (σ=60), 3 times more methane than was produced by the LEA, 140cm(3)-CH4g-VS(-1) (σ=30). Results illustrate current anaerobic modeling efforts in microalgae to biofuel assessments are ...
Xing Bao-Shan BS College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou 310036, China; Key Laboratory of Hangzhou City for Ecosystem Protection and Restoration, Hangzhou Normal University, Hangzhou 310036, - - 2014
In this study, the individual and interactive effects of influent substrate concentration (TNinf), hydraulic retention time (HRT) and upflow velocity (Vup) on the performance of anaerobic ammonium oxidation (anammox) in a granule-based upflow anaerobic sludge blanket (UASB) reactor were investigated by employing response surface methodology (RSM) with a central composite ...
Khan Nasir Mehmood NM Food Chemistry Laboratory, Institute of Agro-Product Processing Science and Technology, Chinese Academy of Agricultural Sciences, No. 2, Yuan Ming Yuan West Road, Haidian District, Beijing 100193, China; Department of Biotechnology, Shaheed Benazir Bhutto University, Sheringal, Dir (Upper) 18000, - - 2015
The effects of high hydrostatic pressure (HHP) on emulsifying properties of sweet potato protein (SPP) in presence of 0.1%, 0.3% and 0.5% (w/v) of guar gum (GG) and glycerol monostearate (GMS) were investigated. Emulsifying stability index (ESI) of the SPP with GG revealed significant increase (P<0.05) in ESI value at ...
Godinho Raquel R CIBIO/InBio - Centro de Investigação em Biodiversidade e Recursos Genéticos, Universidade do Porto, Campus Agrário de Vairão, 4485-661, Vairão, - - 2014
Wolves and dogs provide a paradigmatic example of the ecological and conservation implications of hybridization events between wild and domesticated forms. However, our understanding of such implications has been traditionally hampered by both high genetic similarity and the difficulties in obtaining tissue samples (TS), which limit our ability to assess ...
Zarezade Ali - - 2014
This paper presents a robust tracking approach to handle challenges such as occlusion and appearance change. Here, the target is partitioned into a number of patches. Then, the appearance of each patch is modeled using a dictionary composed of corresponding target patches in previous frames. In each frame, the target ...
Zhang Chunmin C Key Laboratory of Yangtze Water Environment of Ministry of Education, State Key Laboratory of Pollution Control and Resource Reuse, Tongji University, Shanghai 200092, - - 2014
Supplementing proper nutrients could be a strategy for enhancing algal biomass, nutrients uptake and lipid accumulation in the coupling system of biodiesel production and municipal wastewater treatment. However, there is scant information reporting systematic studies on screening and optimization of key supplemented components in the coupling system. The main factors ...
Nice Chris C - - 2014
An important and largely unaddressed issue in studies of biotic-abiotic relationships is the extent to which closely related species, or species living in similar habitats, have similar responses to weather. We addressed this by applying a hierarchical, Bayesian analytical framework to a long-term data set for butterflies which allowed us ...
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