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Bai Zhonghao Z a The State Key Laboratory of Advanced Design and Manufacturing for Vehicle Body , Hunan University , Hunan , - - 2014
Objective: The development of the adaptive occupant restraint system (AORS) has led to an innovative way to optimize such systems for multiple size occupants. An AORS consists of multiple units such as adaptive air bags, seat belts, etc. During a collision, as a supplemental protective device, air bags can provide ...
Parenteau Chantal S CS a International Center for Automotive Medicine , University of Michigan , Ann Arbor , - - 2014
Objective: Abdominal injuries resulting from vehicle crashes can be significant, in particular when undetected. In this study, abdominal injuries for occupants involved in frontal impacts were assessed using crash and medical data. Methods: Injury rates and patterns were first assessed with respect to thoracic injuries. A statistical analysis was then ...
Yang Kyunghee K Division of PharmacotherapyExperimental Therapeutics; UNC Eshelman School of Pharmacy; The University of North Carolina at Chapel Hill; Chapel Hill; NC - - 2014
Troglitazone (TGZ) caused delayed, life-threatening drug-induced liver injury (DILI) in some patients, but was not hepatotoxic in rats. This study investigated altered bile acid (BA) homeostasis as a mechanism of TGZ hepatotoxicity using a systems pharmacology model incorporating drug/metabolite disposition, BA physiology/pathophysiology, hepatocyte life cycle, and liver injury biomarkers. In ...
Ballert Carolina S CS Swiss Paraplegic Research (SPF), Nottwil, Switzerland; Department of Health Sciences and Health Policy, University of Lucerne; ICF Research Branch of WHO Collaborating Center for the Family of International Classifications in - - 2014
To determine the most robust dimensional structure of the International Classification of Functioning, Disability and Health (ICF) categories relevant to spinal cord injury (SCI) across subgroups of [1] lesion level, [2] health care context, [3] gender, [4] age, and [5] the countries' resources. A multidimensional between-item response Rasch model was ...
Culley Joan M JM Columbia, SC, New Orleans; LA, Charleston, SC. Electronic address: - - 2014
Lack of outcomes-based research results in uncertainty about the effectiveness of any of the current triage systems in determining priority of care during actual chemical disasters. The purpose of this study was to determine whether the level of injury severity extrapolated from 5 triage systems correlated with actual injury severity ...
Moen M H MH Bergman Clinics, Naarden, The Netherlands The Sportsphysician Group, St Lucas Andreas Hospital, Amsterdam, The - - 2014
Previous studies on the prognostic value of clinical and MRI parameters for the time to return to play (TTRTP) in acute hamstring injuries showed only limited to moderate evidence for the various investigated parameters. Some studies had multiple methodological limitations, including retrospective designs and the use of univariate analysis only. ...
Silva Luiziana Ferreira da LF Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo. Av. Prof. Lineu Prestes, 1374, 05508-000, São Paulo, SP, Brazil. Electronic address: - - 2014
Polyhydroxyalkanoates (PHA) are biodegradable and biocompatible bacterial thermoplastic polymers that can be obtained from renewable resources. The high impact of the carbon source in the final cost of this polymer has been one of the major limiting factors for PHA production and agricultural residues, mainly lignocellulosic materials, have gained attention ...
Lingsma Hester H Erasmus MC, Public Health , Room AE-138 , PO BOX 2040 , Rotterdam, Netherlands , 3000 CA , Netherlands ; - - 2014
Background Although the majority of patients with mild traumatic brain injury (mTBI) recover completely, some still suffer from disabling ailments at 3 or 6 months. We validated existing prognostic models for mTBI, and explored predictors of poor outcome after mTBI. Methods We selected patients with mTBI from TRACK-TBI Pilot; an ...
Panzer Matthew B MB Center for Applied Biomechanics, Dept. of Mechanical and Aerospace Engineering, University of Virginia, USA. Electronic address: - - 2014
Scaling is an essential component for translating the clinical outcomes of a neurotrauma model to the human equivalent. This article reviews the principles of biomechanical scaling for traumatic brain injuries, and a number of different approaches to scaling the dose (inputs) and response (outputs) of an animal model to humans ...
Garrard Lili L University of Kansas School of Nursing, Kansas City, USA University of Kansas School of Medicine, Kansas City, USA - - 2014
Although remarkable efforts have been made to improve patient fall reporting through the utilization of standardized definitions, injury falls reporting has rarely been examined. This study used an overall intra-class correlation coefficient (ICC) estimate and factor analysis to assess the reliability and validity of the National Database of Nursing Quality ...
Wu Qiong Q Department of Civil Engineering, University of New Mexico, MSC01 1070, 1 University of New Mexico, Albuquerque, NM 87131, United States. Electronic address: - - 2014
Crashes occurring on rural two-lane highways are more likely to result in severe driver incapacitating injuries and fatalities. In this study, mixed logit models are developed to analyze driver injury severities in single-vehicle (SV) and multi-vehicle (MV) crashes on rural two-lane highways in New Mexico from 2010 to 2011. A ...
Ekeløf Sarah S Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, 2730, Herlev, Denmark, - - 2014
Myocardial ischemia-reperfusion injury is a clinical challenge in interventional cardiology, and at the moment, no pharmacological agent is universally accepted in the prevention. In order to prevent inappropriate clinical trials, a potential pharmacological agent should be proved reproducibly effective in clinically relevant experimental studies before initiation of human studies. The ...
Nelson J Gard JG Department of Chemistry, Institute for Biophysical Dynamics, and Computation Institute, University of Chicago , 5735 S. Ellis Ave., Chicago, Illinois 60637, United - - 2014
Accurately calculating a weak acid's pK a from simulations remains a challenging task. We report a multiscale theoretical approach to calculate the free energy profile for acid ionization, resulting in accurate absolute pK a values in addition to insights into the underlying mechanism. Importantly, our approach minimizes empiricism by mapping ...
Mohamed Rayman R Wayne State University, United States. Electronic address: - - 2014
There is a considerable literature on the relationship between sprawl and accidents. However, these studies do not account for the spatially correlated effects of sprawl on accidents. In our analysis of 122 jurisdictions in Southeast Michigan, we use a Bayesian spatial autoregressive model to estimate how injuries and fatalities in ...
Jiang Xinguo X a College of Transportation and Logistics , Southwest Jiaotong University , Chengdu , - - 2014
ABSTRACT Objective & Methods: In the traditional injury-severity related studies two-vehicle and three-vehicle crashes are typically considered in a combinatory manner and thus the injury casual factors for these two crash types are implicitly assumed to be the same. The paper attempts to investigate the potential discrepancy between two- and ...
Lücking Robert R Science and Education, The Field Museum, Chicago, IL 60605; - - 2014
The number of Fungi is estimated at between 1.5 and 3 million. Lichenized species are thought to make up a comparatively small portion of this figure, with unrecognized species richness hidden among little-studied, tropical microlichens. Recent findings, however, suggest that some macrolichens contain a large number of unrecognized taxa, increasing ...
Zhang Yuanyuan Y Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China. Electronic address: - - 2014
Cryptic species, which are an important component of biodiversity, have rarely been studied in South China karst. We investigated cryptic diversity in the cave species complex Telema cucurbitina, which has a narrow niche but widespread distribution among multiple caves. We sampled another 15 populations (caves) in addition to the population ...
Harper Jonathan D JD Department of Urology, University of Washington School of Medicine, Seattle, WA. Electronic address: - - 2014
To provide an update on a research device to ultrasonically reposition kidney stones transcutaneously. This article reports preclinical safety and effectiveness studies, survival data, modifications of the system, and testing in a stone-forming porcine model. These data formed the basis for regulatory approval to test the device in humans. The ...
Lee Chris C Department of Civil and Environmental Engineering, University of Windsor, ON, N9B 3P4, Canada. Electronic address: - - 2014
This study analyzes driver's injury severity in single- and two-vehicle crashes and compares the effects of explanatory variables among various types of crashes. The study identified factors affecting injury severity and their effects on severity levels using 5-year crash records for provincial highways in Ontario, Canada. Considering heteroscedasticity in the ...
de Oliveira Marcelo E ME a Robotic Systems Laboratory, Swiss Federal Institute of Technology , Lausanne , - - 2014
In attempts to elucidate the underlying mechanisms of spinal injuries and spinal deformities, several experimental and numerical studies have been conducted to understand the biomechanical behavior of the spine. However, numerical biomechanical studies suffer from uncertainties associated with hard- and soft-tissue anatomies. Currently, these parameters are identified manually on each ...
Liu Fangping F College of Veterinary Medicine, Northeast Agricultural University, Harbin, PR China. Electronic address: - - 2014
Three acute hepatic injury models (a CCl4-induced model, APAP-induced model and ethanol-induced model) in mice were used to study the importance of GSTA1 in acute hepatic injury by comparison with a standard enzyme marker, alanine aminotransferase (ALT). GSTA1 release was demonstrated to be an earlier and more sensitive indicator of ...
Forgione Nicole N University Health Network, Genetics and Development, Toronto, Ontario, Canada ; - - 2014
Despite the increasing incidence and prevalence of cervical spinal cord injury (cSCI), we lack clinically relevant animal models that can be used to study the pathomechanisms of this injury and test new therapies. Here, we characterize a moderate cervical contusion-compression model in rats that is similar to incomplete traumatic cSCI ...
Karatzas Theodore T Laboratory of Experimental Surgery and Surgical Research "N. S. Christeas", School of Medicine, University of Athens, Athens, Greece; 2(nd) Department of Propedeutic Surgery, School of Medicine, University of Athens, Athens, - - 2014
Ischemia and reperfusion (IR) injury remains one of the major problems in liver surgery and transplantation, which determines the viability of the hepatic tissue after resection and of the grafted organ. This review aims to elucidate the mechanisms involved in IR injury of the liver in rodent experimental studies and ...
Strauss Jillian J Department of Civil Engineering and Applied Mechanics, McGill University, Macdonald Engineering Building, 817 Sherbrooke Street West, Montréal, Quebec H3A 0C3 Canada. Electronic address: - - 2014
This paper proposes a multimodal approach to study safety at intersections by simultaneously analysing the safety and flow outcomes for both motorized and non-motorized traffic. This study uses an extensive inventory of signalized and non-signalized intersections on the island of Montreal, Quebec, Canada, containing disaggregate motor-vehicle, cyclist and pedestrian flows, ...
Mayer Andrew R AR The Mind Research Network/Lovelace Biomedical and Environmental Research Institute, Albuquerque, New Mexico; Neurology Department, University of New Mexico School of Medicine, Albuquerque, New Mexico; Department of Psychology, University of New Mexico, Albuquerque, New - - 2014
Algorithms that are capable of capturing subject-specific abnormalities (SSA) in neuroimaging data have long been an area of focus for diverse neuropsychiatric conditions such as multiple sclerosis, schizophrenia, and traumatic brain injury. Several algorithms have been proposed that define SSA in patients (i.e., comparison group) relative to image intensity levels ...
Assas Laila L a Department of Mathematics , Umm Al-Qura University , B.O.X 10265, Makkah , Saudi - - 2014
We consider a two-species hierarchical competition model with a strong Allee effect. The Allee effect is assumed to be caused by predator saturation. Moreover, we assume that there is a 'silverback' species x that gets first choice of the resources and where growth is limited by its own intraspecific competition, ...
Granato Daniel D a Instituto Adolfo Lutz- Núcleo de Análise e Tratamento de Dados-Av. Dr. Arnaldo , 355 , 01246-902 , São Paulo , - - 2014
Abstract Tea presents a diverse phenolic composition which is responsible for its alleged biological activities, including the in vivo and in vitro antioxidant capacity. It is very usual to find researches applying univariate statistical methods, such as analysis of variances (ANOVA) and linear Pearson correlation coefficients to analyze the strength ...
Dams-OʼConnor Kristen K Department of Rehabilitation Medicine, Icahn School of Medicine at Mount Sinai, New York (Dr Dams-O'Connor and Mr Billah); Research Department, Craig Hospital, Englewood, Colorado (Drs Pretz and Harrison-Felix); and Indiana University School of Medicine, Indianapolis (Dr - - 2014
To compare long-term functional outcome trajectories of individuals with traumatic brain injury (TBI) who survive with those who expire more than 5 years postinjury, using individual growth curve analysis. Secondary analysis of data from a multicenter longitudinal cohort study. Acute inpatient rehabilitation facilities that are current or former TBI Model ...
Crespo-Pérez Verónica V IRD, UR 072, Diversité, Ecologie et Evolution des Insectes Tropicaux, Laboratoire Evolution, , Génomes et Spéciation, UPR 9034, CNRS, 91198 Gif-sur- Yvette Cedex, Université Paris-Sud 11, 91405, Orsay Cedex, France; Laboratorio de Entomología, Facultad de Ciencias Exactas y Naturales, Pontificia Universidad Católica del Ecuador, 12 de Octubre, 1076 y Roca, Quito, Ecuador; Centre d'Ecologie Fonctionnelle et Evolutive, CNRS, 1919 route de Mende, 34293, Montpellier cedex 5, - - 2014
Climate induced species range shifts might create novel interactions among species that may outweigh direct climatic effects. In an agricultural context, climate change might alter the intensity of competition or facilitation interactions among pests with, potentially, negative consequences on the levels of damage to crop. This could threaten the productivity ...
Leclerc Eric E CNRS UMR 7338, Laboratoire de Biomécanique et Bioingénierie, Université de Technologie de Compiègne, France. Electronic address: - - 2014
We present a systems biology analysis of rat primary hepatocytes response after exposure to 10 μM and 100 μM flutamide in liver microfluidic biochips. We coupled an in vitro pharmacokinetic (PK) model of flutamide to a system biology model of its reactive oxygen species (ROS) production and scavenging by the ...
Zhang Qi Q Center For Applied Biomechanics, University of Virginia, USA. Electronic address: - - 2014
Clavicle injuries were frequently observed in automotive side and frontal crashes. Finite element (FE) models have been developed to understand the injury mechanism, although no clavicle loading response corridors yet exist in the literature to ensure the model response biofidelity. Moreover, the typically developed structural level (e.g., force-deflection) response corridors ...
Anderson R W G RW Centre for Automotive Safety Research, The University of Adelaide, Adelaide 5005, SA, Australia. Electronic address: - - 2014
This paper presents the head kinematics of a novel ovine model of non-accidental head injury (NAHI) that consists only of a naturalistic oscillating insult. Nine, 7-to-10-day-old anesthetized and ventilated lambs were subjected to manual shaking. Two six-axis motion sensors tracked the position of the head and torso, and a triaxial ...
Cheriyan T T Department of Orthopaedic Surgery, Hospital for Joint Diseases, New York Langone Medical Center, New York, NY, - - 2014
Background:Animal spinal cord injury (SCI) models have proved invaluable in better understanding the mechanisms involved in traumatic SCI and evaluating the effectiveness of experimental therapeutic interventions. Over the past 25 years, substantial gains have been made in developing consistent, reproducible and reliable animal SCI models.Study design:Review.Objective:The objective of this review ...
Shen Yongjun Y a Transportation Research Institute (IMOB) - Hasselt University Wetenschapspark 5 bus 6, 3590 Diepenbeek, Belgium , +32 11 26 91 43 , +32 11 26 91 99 , elke.hermans@uhasselt.be , qiong.bao@uhasselt.be , tom.brijs@uhasselt.be , - - 2014
Abstract Objectives: Almost all of the current road safety benchmarking studies focus entirely on fatalities, which however, represent only one measure of the magnitude of the road safety problem. The main objective of this paper was to investigate the possibility of including the number of serious injuries in addition to ...
Bae Sung-Man SM Department of Psychiatry, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, South Korea; Department of Psychology, Chung-Ang University, Seoul, South - - 2014
The purpose of this study was to develop and test a model (including cognitive appraisal, coping strategy, and forgiveness variables) predicting post-traumatic stress disorder (PTSD) in 127 adults who were involved in traffic accidents. Participants were recruited from the inpatient and outpatient departments of three urban hospitals in South Korea. ...
Garjan Tahereh Ghadiri TG School of advanced medical technologies, Tehran University of Medical Sciences, Tehran, Iran; Shefa Neuroscience Research Center, Tehran, - - 2014
Due to the marked heterogeneity of human traumatic brain injury (TBI), none of the available animal model can reproduce the entire spectrum of TBI, especially mild focal TBI. This study was designed to develop a modified TBI weight drop model for induction of focal mild cerebral injury. New method: A ...
Polders Evelien E a Transportation Research Institute (IMOB) , Hasselt University , Wetenschapspark 5 Bus 6, BE-3590 Diepenbeek , Belgium , Fax: +32(0)11 26 91 99 , Tel.: +32(0)11 26 91-{ 44; 56;/; 55} , E-mail: evelien.polders@uhasselt.be stijn.daniels@uhasselt.be ; - - 2014
Abstract Objectives: Roundabouts are a type of circular intersection control generally associated with a favourable influence on traffic safety. International studies of intersections converted to roundabouts indicate a strong reduction in injury crashes, particularly for crashes with fatal or serious injuries. Nevertheless, some crashes still occur at roundabouts. The present ...
Sarmento Sandra M SM Universidade Federal de Pernambuco, Departamento de Engenharia Química; Av. Prof. Artur de Sá, SN., Cidade Universitária, CEP: 50740-521, Recife, PE, Brazil E-mail: - - 2014
This work is concerned with the intrinsic reaction kinetic of the degradation of atrazine (ATZ) using H2O2-UVC. Experimental runs were carried out in annular photoreactor. The initial concentration of ATZ was 2.2 × 10(-2) mol m(-3) while the H2O2-ATZ molar ratio range was 0-578 mol H2O2 mol(-1) ATZ. The ATZ ...
Peter Claudio C Swiss Paraplegic Research (SPF), Nottwil, Switzerland, - - 2014
The aims of the study were (1) to examine the associations between the psychological resources general self-efficacy (GSE) and purpose in life (PIL), appraisals, coping and life satisfaction, and (2) to examine whether the effects of the psychological resources on life satisfaction are mediated by appraisals and coping, as proposed ...
Gullotti David M - - 2014
Although blast-induced traumatic brain injury (bTBI) is well recognized for its significance in the military population, the unique mechanisms of primary bTBI remain undefined. Animate models of primary bTBI are critical for determining these potentially unique mechanisms, but the biomechanical characteristics of many bTBI models are poorly understood. In this ...
Bochmann Frank F IFA-Institute for Occupational Safety and Health of the German Social Accident Insurance, Sankt Augustin, - - 2014
Prevention Index (PI-TOP) is a practical measurement tool which is currently used to monitor injury prevention activities at workplaces. This 12-item scoring system has 3 subscales rating technical, organisational and personnel-related internal safety conditions of a company. The reliability and validity of this instrument were evaluated in a cross-sectional survey ...
Winsberg Eric - - 2014
This paper discusses a crisis of accountability that arises when scientific collaborations are massively epistemically distributed. We argue that social models of epistemic collaboration, which are social analogs to what Patrick Suppes called a "model of the experiment," must play a role in creating accountability in these contexts. We also ...
Abegaz Teferi - - 2014
In recent years, there has been an increasing interest in implementing road safety policy by different low income countries. However; the evidence is scarce on its success in the reduction of crashes, injuries and deaths. This study was conducted to assess whether road crashes, injuries and fatalities was reduced following ...
Ballert Carolina S CS Swiss Paraplegic Research (SPF), Nottwil, Switzerland; Department of Health Sciences and Health Policy, University of Lucerne; ICF Research Branch of WHO Collaborating Center for the Family of International Classifications in - - 2014
To determine whether ICF categories relevant to SCI can be integrated in clinical measures and get insights to guide their future operationalization. Specific aims are to find out whether the ICF categories relevant to SCI [1] fit a Rasch model taking into consideration the dimensionality found in previous investigations, [2] ...
Kerr Zachary Y ZY Datalys Center for Sports Injury Research and Prevention, Inc, Indianapolis, - - 2014
Background :  Since 1982, the National Collegiate Athletic Association has used the Injury Surveillance System (ISS) to collect injury and athlete-exposure data from a representative sample of collegiate institutions and sports. At the start of the 2004-2005 academic year, a Web-based ISS replaced the paper-based platform previously used for reporting ...
Abegaz Teferi T School of Public and Environmental Health, College of Medicine and Health Sciences, Hawassa University, Hawassa, Ethiopia. Electronic address: - - 2014
The severity of injury from vehicle crash is a result of a complex interaction of factors related to drivers' behavior, vehicle characteristics, road geometric and environmental conditions. Knowing to what extent each factor contributes to the severity of an injury is very important. The objective of the study was to ...
Lalu Manoj M - - 2014
Acute respiratory distress syndrome (ARDS) in humans is caused by an unchecked proinflammatory response that results in diffuse and severe lung injury, and it is associated with a mortality rate of 35 to 45%. Mesenchymal stromal cells (MSCs; 'adult stem cells') could represent a promising new therapy for this syndrome, ...
Stylianou Neophytos N Centre for Health Informatics, Institute of Population Health, University of Manchester, United - - 2014
Mortality among patients treated in hospital for burn is routinely examined, but none of the many models in use in the UK was developed using nationwide data. The aim of this research was to develop a prediction model using national data, representative of the British population. Data were gathered from ...
Monroe Andrew E AE Florida State University, USA. Electronic address: - - 2014
Belief in free will is widespread, and this belief is supposed to undergird moral and legal judgment. Despite the importance of the free will concept, however, there remains widespread confusion regarding its definition and its connection to blame. We address this confusion by testing two prominent models of the folk ...
Chase Rachel P RP Departments of International Health (Ms Chase) and Mental Health (Dr Nevin), Johns Hopkins Bloomberg School of Public Health, Baltimore, - - 2014
To estimate the number of undocumented incident traumatic brain injuries (TBIs) among active component US military personnel serving in Iraq and Afghanistan prior to policy changes implemented in late 2006 and 2010 that improved TBI documentation. Negative binomial regression was used to model monthly incident TBI counts between December 2010 ...
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