Search Results
Results 1 - 50 of 2269
1 2 3 4 5 6 7 8 9 10 >
Shailendra Bhatt B MahrishiArvind Institute of Pharmacy, Mansarovar, Jaipur-302020, Rajasthan, India. - - 2014
The main aim of this work was to optimize fast dissolving tablet (FDT) formulation using response surface approach. The variables studied were sodium bicarbonate (X1), citric acid (X2), and superdisintegrant, Ac-Di-Sol (X3). The main aspect of present work was to develop FDT of Domperidone with fast disintegration and high mechanical ...
van der Sman R G M RG Agrotechnology Food Sciences Group, Wageningen University & Research, The Netherlands. - - 2014
We investigate the effect of salt on the expansion of starchy snacks during frying by means of a multiscale simulation model. This model has been developed earlier for starchy snacks without salt. The simulation results are analysed by means of the supplemented state diagram. We have found that the optimal ...
Saini V V a Toxicology & Computational Biology Group, Centre for Bioinformatics , M.D. University , Rohtak , Haryana , - - 2014
DDT has enjoyed the reputation of a successful pesticide in disease control programme and agricultural practices along with the serious opposition and ban later on due to its biomagnification and toxic action against non-target organisms. The present work was carried out to develop QSAR models for analysing DDT analogues for ...
Ding Liang L University of Chinese Academy of Science, Beijing 100049, China; State Key Laboratory of Coal Conversion, Institute of Coal Chemistry, Chinese Academy of Science, Taiyuan, Shanxi 030001, - - 2014
Co-gasification of coal char and biomass char was conducted to investigate the interactions between them. And random pore model (RPM) and modified random pore model (MRPM) were applied to describe the gasification behaviors of the samples. The results show that inhibiting effect was observed during co-gasification of corn stalk char ...
Shi Ya-Zhou YZ Department of Physics and Key Laboratory of Artificial Micro- and Nano-Structures of Ministry of Education, School of Physics and Technology, Wuhan University, Wuhan 430072, - - 2014
To bridge the gap between the sequences and 3-dimensional (3D) structures of RNAs, some computational models have been proposed for predicting RNA 3D structures. However, the existed models seldom consider the conditions departing from the room/body temperature and high salt (1M NaCl), and thus generally hardly predict the thermodynamics and ...
Reilly Matthew A MA Biomedical Engineering; University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas, 78249. Electronic address: - - 2014
This study expands on a geometric model of ocular accommodation (Reilly and Ravi, Vision Res. 50:330-336; 2010) by relaxing assumptions regarding lens symmetry about the equator. A method for predicting stretching force was derived. Two models were then developed: Model 1 held the equatorial geometry constant at all stages of ...
Wang Liang L Centre for Environmental Risk Assessment and Remediation, University of South Australia, Mawson Lakes, SA 5095, Australia; CRC for Contamination Assessment and Remediation of Environment, Mawson Lakes Boulevard, Mawson Lakes, SA 5095, Australia. Electronic address: - - 2015
Sodium potassium absorption ratio (SPAR) is an important measure of agricultural water quality, wherein four exchangeable cations (K(+), Na(+), Ca(2+) and Mg(2+)) should be simultaneously determined. An ISE-array is suitable for this application because its simplicity, rapid response characteristics and lower cost. However, cross-interferences caused by the poor selectivity of ...
Hajihosseinali M M Department of Mechanical Engineering, Sharif University of Technology, Tehran, - - 2014
An anatomically detailed eighteen-rotational-degrees-of-freedom model of the human spine using optimization constrained to equilibrium and stability requirements is developed and used to simulate several symmetric tasks in upright and flexed standing postures. Predictions of this stability and kinematics-driven (S+KD) model for trunk muscle forces and spine compressive/shear loads are compared ...
Fernandez-Navarro Francisco - - 2014
This paper introduces a new instance-based algorithm for multiclass classification problems where the classes have a natural order. The proposed algorithm extends the state-of-the-art gravitational models by generalizing the scaling behavior of the class-pattern interaction force. Like the other gravitational models, the proposed algorithm classifies new patterns by comparing the ...
Roy Rajarshi R Robotics, Automation, and Medical Systems (RAMS) Laboratory, Department of Mechanical Engineering, University of Maryland, College Park, MD, USA, - - 2014
This paper outlines a comprehensive parametric approach for quantifying mechanical properties of spatially heterogeneous thin biological specimens such as human breast tissue using contact-mode Atomic Force Microscopy. Using inverse finite element (FE) analysis of spherical nanoindentation, the force response from hyperelastic material models is compared with the predicted force response ...
Fitzpatrick Clare K CK Center for Orthopaedic Biomechanics, University of Denver, 2390 S. York St., Denver, CO 80208, USA. Electronic address: - - 2014
Accurate prediction of loads acting at the joint in total knee replacement (TKR) patients is key to developing experimental or computational simulations which evaluate implant designs under physiological loading conditions. In vivo joint loads have been measured for a small number of telemetric TKR patients, but in order to assess ...
Kucheva Yana Y Center on Poverty and Inequality, Stanford University, Building 370, 450 Serra Mall, Palo Alto, CA 94305, United States. Electronic address: - - 2014
Shelley v. Kraemer (1948) was a landmark civil rights ruling, in which the Supreme Court held that private racial covenants could not be enforced by the state to evict black buyers of "restricted" homes. Fair housing scholars have generally dismissed or downplayed the practical effects of Shelley, since other forms ...
Fierens T T Flemish Institute for Technological Research (VITO), Boeretang 200, B-2400 Mol, Belgium; Ghent University, Department of Public Health, Faculty of Medicine and Health Sciences, De Pintelaan 185, B-9000 Ghent, Belgium. Electronic address: - - 2014
This study aimed to predict the occurrence of four phthalates, two polychlorinated dibenzo-p-dioxins and two polychlorinated dibenzofurans in environmental and agricultural media from observed concentrations in air, sludge, manure and concentrate. For the environmental and agricultural fate modelling, the newly developed multimedia model "EN-forc" (ENvironmental Food transfer model for ORganic ...
Wen Shuhuan S Key Lab of Industrial Computer Control Engineering of Hebei Province, Yanshan University, Qinhuangdao 066004, China. Electronic address: - - 2014
Robot force control is an essential issue in robotic intelligence. There is much high uncertainty when robot end-effector contacts with the environment. Because of the environment stiffness effects on the system of the robot end-effector contact with environment, the adaptive generalized predictive control algorithm based on quantitative feedback theory is ...
Kim Seyoung S Department of Robotics and Mechatronics, Korea Institute of Machinery & Materials (KIMM), Daejeon, South Korea. Electronic address: - - 2014
In this study, we developed a curve-fit model of countermovement dynamics and examined whether the characteristics of a countermovement jump can be quantified using the model parameter and its scaling; we expected that the model-based analysis would facilitate an understanding of the basic mechanisms of force reduction and propulsion with ...
Wang Yancheng Y State Key Lab of Fluid Power Transmission and Control, Zhejiang University, Hangzhou, 310027, China; Department of Mechanical Engineering, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: - - 2014
This research presents a methodology for optimal design of the needle geometry to minimize the insertion force and bevel length based on mathematical models of cutting edge inclination and rake angles and the insertion force. In brachytherapy, the needle with lower insertion force typically is easier for guidance and has ...
Spratley E M EM Orthopaedic Research Laboratory, Departments of Biomedical Engineering and Orthopaedic Surgery, Virginia Commonwealth University, Richmond, VA, - - 2014
Following IRB approval, a cohort of 3-D rigid-body computational models was created from submillimeter MRIs of clinically diagnosed Adult Acquired Flatfoot Deformity patients and employed to investigate postoperative foot/ankle function and surgical effect during single-leg stance. Models were constrained through physiologic joint contact, passive soft-tissue tension, active muscle force, full ...
Chang Yow-Ren YR Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California Davis, Davis, California 95616, - - 2014
The analysis of atomic force microscopy (AFM) force data requires the selection of a contact point (CP) and is often time consuming and subjective due to influence from intermolecular forces and low signal-to-noise ratios (SNR). In this report, we present an automated algorithm for the selection of CPs in AFM ...
Hermanowicz PaweĊ‚ P Department of Plant Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7, 30-387 Kraków, - - 2014
We present an open source Java application for analysis of force curves and images recorded with the Atomic Force Microscope. AtomicJ supports a wide range of contact mechanics models and implements procedures that reduce the influence of deviations from the contact model. It generates maps of mechanical properties, including maps ...
Larrañeta Eneko E Queens University, Belfast School of Pharmacy, 97 Lisburn Road, Belfast BT9 7BL, United - - 2014
A commercial polymeric film (Parafilm M(®), a blend of a hydrocarbon wax and a polyolefin) was evaluated as a model membrane for microneedle (MN) insertion studies. Polymeric MN arrays were inserted into Parafilm M(®) (PF) and also into excised neonatal porcine skin. Parafilm M(®) was folded before the insertions to ...
Jung Yihwan Y Department of Mechanical Engineering, Chung-Ang University, 84 Heukseokro, Dongjak-gu, Seoul 156-756, South - - 2014
Kinetic analysis of walking requires joint kinematics and ground reaction force (GRF) measurement, which are typically obtained from a force plate. GRF is difficult to measure in certain cases such as slope walking, stair climbing, and track running. Nevertheless, estimating GRF continues to be of great interest for simulating human ...
O' Lee D J DJ Department of Chemistry, Imperial College London, SW7 2AZ, London, - - 2014
We consider mechanically generated molecular braids composed of two molecules where long range interactions between them can be considered to be very weak. We describe a model that takes account of the thermal fluctuations of the braid, steric interactions between the molecules, and external mechanical forces. In this model, both ...
Nostheide Sandra S Fachbereich Physik, Universität Osnabrück, Barbarastraße 7, 49076 Osnabrück, - - 2014
DNA hairpin molecules with periodic base sequences can be expected to exhibit a regular coarse-grained free energy landscape (FEL) as a function of the number of open base pairs and applied mechanical force. Using a commonly employed model, we first analyze for which types of sequences a particularly simple landscape ...
Braunsmann Christoph C Institute of Applied Physics and LISA+, University of Tübingen, Auf der Morgenstelle 10, 72076 Tübingen, - - 2014
Force curves recorded with the atomic force microscope on structured samples often show an irregular force versus indentation behavior. An analysis of such curves using standard contact models (e.g., the Sneddon model) would generate inaccurate Young's moduli. A critical inspection of the force curve shape is therefore necessary for estimating ...
Mootanah R R a Medical Engineering Research Group, Faculty of Science and Technology, Anglia Ruskin University , Chelmsford, Essex , - - 2014
A three-dimensional (3D) knee joint computational model was developed and validated to predict knee joint contact forces and pressures for different degrees of malalignment. A 3D computational knee model was created from high-resolution radiological images to emulate passive sagittal rotation (full-extension to 65°-flexion) and weight acceptance. A cadaveric knee mounted ...
Kasperek Regina - - 2014
For increased analgesic effect, new composed tablets containing diclofenac sodium (DIC) with an addition of papaverine hydrochloride (PAP) were prepared to investigate the mechanism of release of the active substances from tablets with different excipients in eight different formulations. To detect the possible interactions between active substances and excipients differential ...
Ní Annaidh Aisling A From the *School of Mechanical and Materials Engineering, University College Dublin, Belfield; and †Office of the State Pathologist, Fire Brigade Training Centre, Marino; and ‡School of Mathematics, Statistics and Applied Mathematics, National University of Ireland Galway, Galway, - - 2014
Collaborative research between the disciplines of forensic pathology and biomechanics was undertaken to investigate the hyperelastic properties of human skin, to determine the force required for sharp instrument penetration of skin, and to develop a finite element model, which reflects the mechanisms of sharp instrument penetration. These studies have led ...
Na Hyuntae H Department of Computer Science, Iowa State University, 226 Atanasoff Hall, Ames, Iowa 50011, - - 2014
The Gaussian network model (GNM) and anisotropic network model (ANM) are two elastic network models that have been widely used to study protein fluctuation dynamics. Both models have strengths and weaknesses. Attempts have been made in the past to unify the two models but they had severe limitations. This work ...
Wang Yuan Y Department of Atmospheric Sciences, Texas A&M University, College Station, TX - - 2014
Atmospheric aerosols affect weather and global general circulation by modifying cloud and precipitation processes, but the magnitude of cloud adjustment by aerosols remains poorly quantified and represents the largest uncertainty in estimated forcing of climate change. Here we assess the effects of anthropogenic aerosols on the Pacific storm track, using ...
Rees Daniel I DI Department of Economics, University of Colorado Denver, Denver, CO, - - 2014
While migraine headache can be physically debilitating, no study has attempted to estimate its effects on labor market outcomes. Using data drawn from the National Longitudinal Study of Adolescent Health, we estimate the effect of being diagnosed with migraine headache on labor force participation, hours worked, and wages. Ordinary least ...
Kurmi Moolchand M Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, 160062 Punjab, - - 2014
The study involved optimization of forced degradation conditions and development of a stability-indicating method (SIM) for furosemide employing the design of experiment (DoE) concept. The optimization of forced degradation conditions, especially hydrolytic and oxidative, was done by application of 2(n) full factorial designs, which helped to obtain the targeted 20-30% ...
Coenen Pieter P MOVE Research Institute Amsterdam, Faculty of Human Movement Sciences, VU University Amsterdam, , Amsterdam, The - - 2014
Reported associations of physical exposures during work (eg, lifting, trunk flexion or rotation) and low-back pain (LBP) are rather inconsistent. Mechanical back loads (eg, moments on the low back) as a result of exposure to abovementioned risk factors have been suggested to be important as such loads provide a more ...
Ackerman Jeffrey J School of Mechanical Engineering, Purdue University, 585 Purdue Mall, West Lafayette, IN 47907 2088, - - 2014
Elastically-suspended loads have been shown to reduce the peak forces acting on the body while walking with a load when the suspension stiffness and damping are minimized. However, it is not well understood how elastically-suspended loads can affect the energetic cost of walking. Prior work shows that elastically suspending a ...
Piazzesi Gabriella G Laboratory of Physiology, Department of Biology, University of Florence, Via G. Sansone 1, 50019 Sesto Fiorentino (FI), Italy. Electronic address: - - 2014
The half-sarcomere is the functional unit of striated muscle, in which, according to a "linear" mechanical model, myosin motors are parallel force generators with an average strain s acting between the opposing myosin and actin filaments that behave as a series elastic element with compliance Cf. Thus the definition of ...
Wang Wei W State Key Laboratory of Microbial metabolism, Department of Bioinformatics and Biostatistics, College of Life Sciences and Biotechnology, Shanghai Jiaotong University, 800 Dongchuan Road, Shanghai, 200240, - - 2014
Intrinsically disordered proteins (IDPs) or intrinsically disordered protein regions comprise a large portion of eukaryotic proteomes (between 35% and 51%). These IDPs were found to link with cancer and various other diseases. However, widely used additive force field parameter sets are insufficient in quantifying the structural properties of IDPs. Therefore, ...
Keener James P JP Department of Mathematics, University of Utah, Salt Lake City, UT - - 2014
Important mechanical events during mitosis are facilitated by the generation of force by chromosomal kinetochore sites that attach to dynamic microtubule tips. Several theoretical models have been proposed for how these sites generate force, and molecular diffusion of kinetochore components has been proposed as a key component that facilitates kinetochore ...
Burgoyne Hayden A HA Graduate Aerospace Laboratories (GALCIT), California Institute of Technology, Pasadena, California 91125, - - 2014
We present a force-displacement contact model for the compressive loading of elastoplastic spheres. This model builds from the well known Hertz contact law for elastic, quasistatic compression to incorporate a material's strain-rate-dependent plasticity in order to describe collisions between particles. In the quasistatic regime, finite-element analysis is used to derive ...
Hane F T FT Department of Biology, University of Waterloo, 200 University Ave West, Waterloo, ON N2L 3G1, - - 2014
We performed single molecule dynamic force spectroscopy experiments to study the dimerization of two amyloid-β (1-42) peptides and compared three different theoretical models used to fit experimental data: Bell-Evans, Dudko-Hummer-Szabo, and Friddle-De Yoreo. Using these models we extracted values of the dissociation rate at zero force, k0, and height and ...
Mikulska Karolina K Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University, Grudziadzka 5, 87-100, Torun, - - 2014
Computer simulations of protein unfolding substantially help to interpret force-extension curves measured in single-molecule atomic force microscope (AFM) experiments. Standard all-atom (AA) molecular dynamics simulations (MD) give a good qualitative mechanical unfolding picture but predict values too large for the maximum AFM forces with the common pulling speeds adopted here. ...
Miller Ross H RH Department of Kinesiology, University of Maryland, College Park, MD, USA; Neuroscience & Cognitive Science Program, University of Maryland, College Park, MD, USA. Electronic address: - - 2014
The popular Hill model for muscle activation and contractile dynamics has been extended with several different formulations for predicting the metabolic energy expenditure of human muscle actions. These extended models differ considerably in their approach to computing energy expenditure, particularly in their treatment of active lengthening and eccentric work, but ...
Zhu Rui - - 2014
Abstract In only a few published finite element (FE) simulations have muscle forces been applied to the spine. Recently, muscle forces determined using an inverse static (IS) model of the spine were transferred to a spinal FE model, and the effect of methodical parameters was investigated. However, the sensitivity of ...
Sacilotto G B D BD Aquatic Testing, Training and Research Unit, Australian Institute of Sport, Bruce, ACT, Australia, and with the Faculty of Health, University of Canberra, Bruce, ACT, - - 2014
Resistive or drag forces encountered during free swimming greatly influence the swim performance of elite competitive swimmers. The benefits in understanding the factors which affect the drag encountered will enhance performance within the sport. However, the current techniques used to experimentally measure or estimate drag values are questioned for their ...
Travis Anthony S - - 2014
Trace analysis is usually associated with high-sensitivity analysis instrumentation. It became fully established from the 1960s following consensus among different groups of practitioners over protocols, reference materials, sensitivity, and accuracy and precision. As a consequence, wet chemical methods have been relegated to a secondary role, contrasting with their tremendous historical ...
Maykranz Daniel D Locomotion Laboratory Magdalenenstr. 27 64289 Darmstadt, Germany. Electronic address: - - 2014
The spring loaded inverted pendulum (SLIP) model is widely used to predict and explain basic characteristics of human walking and running. Its periodic running solutions can be mirrored at the instant of the vertical orientation of the leg and thus are symmetric between landing and take-off. In contrast, human running ...
Cao Hua H a Département EEA , Haute Etude de l'Ingénieur (HEI) , Lille , - - 2014
The aim of this study was to evaluate a surface electromyography (sEMG) signal and force model for the biceps brachii muscle during isotonic isometric contractions for an experimental set-up as well as for a simulation. The proposed model includes a new rate coding scheme and a new analytical formulation of ...
Fang Wei-Ta WT Graduate Institute of Environmental Education, National Taiwan Normal University, Taipei, Taiwan, - - 2014
Thousands of farm ponds disappeared on the tableland in Taoyuan County, Taiwan since 1920s. The number of farm ponds that have disappeared is 1,895 (37%), 2,667 ponds remain (52%), and only 537 (11%) new ponds were created within a 757 km(2) area in Taoyuan, Taiwan between 1926 and 1960. In ...
Wang Yuan Y 1] Department of Atmospheric Sciences, Center for Atmospheric Chemistry and the Environment, Texas A&M University, College Station, 77843 Texas, USA [2] Jet Propulsion Laboratory, California Institute of Technology, Pasadena, California 91109, - - 2014
Increasing levels of anthropogenic aerosols in Asia have raised considerable concern regarding its potential impact on the global atmosphere, but the magnitude of the associated climate forcing remains to be quantified. Here, using a novel hierarchical modelling approach and observational analysis, we demonstrate modulated mid-latitude cyclones by Asian pollution over ...
Molinari A A Politecnico di Milano, Dipartimento di Ingegneria Civile e Ambientale, Piazza L. Da Vinci 32, 20133 Milano, Italy. Electronic address: - - 2014
The estimation of natural background levels (NBLs) of dissolved concentrations of target chemical species in subsurface reservoirs relies on a proper assessment of the effects of forcing terms driving flow and transport processes taking place within the system and whose dynamics drive background concentration values. We propose coupling methodologies based ...
Thelen Darryl G - - 2014
This study introduces a framework for co-simulating neuromuscular dynamics and knee joint mechanics during gait. A knee model was developed that included 17 ligament bundles and a representation of distributed contact between a femoral component and tibial insert surface. The knee was incorporated into a forward dynamics musculoskeletal model of ...
Ferrant Sylvain S 1] Université de Toulouse, UPS (OMP), GET, 14 av. Edouard Belin, F-31400 Toulouse, France [2] IRD, CNRS, GET, F-31400 Toulouse, France [3] UPS, IRD, CNRS, CNES, CESBIO, 18 av. Edouard Belin 31400 - - 2014
Local groundwater levels in South India are falling alarmingly. In the semi-arid crystalline Deccan plateau area, agricultural production relies on groundwater resources. Downscaled Global Climate Model (GCM) data are used to force a spatially distributed agro-hydrological model in order to evaluate Climate Change (CC) effects on local groundwater extraction (GWE). ...
1 2 3 4 5 6 7 8 9 10 >