Search Results
Results 1 - 50 of 2601
1 2 3 4 5 6 7 8 9 10 >
Mattsson Per P Department of Information Technology, Uppsala University, Box 337, SE-751 05, Uppsala, Sweden, - - 2015
The continuous part of a hybrid (pulse-modulated) model of testosterone (Te) feedback regulation in the human male is extended with infinite-dimensional and nonlinear blocks, to obtain the dynamics that better agree with the hormone concentration profiles observed in clinical data. A linear least-squares based optimization algorithm is developed for the ...
Palabhanvi Basavaraj B Department of Biotechnology, Indian Institute of Technology, Guwahati, Assam 781039, - - 2014
Microalgae are able to grow even under exhaustion of some key nutrients such as nitrogen and phosphorous. Here, we report a multi-nutrient mechanistic model to predict heterotrophic growth of Chlorella sp. FC2 IITG over two sequential phases of fermentation: nutrient sufficient condition to nutrient starved condition. The model assumes that ...
Liu Dan D Department of Oncology, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 7DQ, - - 2014
Tumour cell proliferation can be imaged via positron emission tomography of the radiotracer 3'-deoxy-3'-18F-fluorothymidine (18F-FLT). Conceptually, the number of proliferating cells might be expected to correlate more closely with the kinetics of 18F-FLT uptake than with uptake at a fixed time. Radiotracer uptake kinetics are standardly visualized using parametric maps ...
Jeffery Nicholas W NW Department of Integrative Biology, University of Guelph, Guelph, Ontario, N1G 2W1, - - 2014
Crustaceans are enormously diverse both phylogenetically and ecologically, but they remain substantially underrepresented in the existing genome size database. An expansion of this dataset could be facilitated if it were possible to obtain genome size estimates from ethanol-preserved specimens. In this study, two tests were performed in order to assess ...
Huertas-Fernández I I Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Avda. Manuel Siurot s/n., 41013, Seville, - - 2014
The study's objective was to develop diagnostic predictive models using data from two commonly used [(123)I]FP-CIT SPECT assessment methods: region-of-interest (ROI) analysis and whole-brain voxel-based analysis. We included retrospectively 80 patients with vascular parkinsonism (VP) and 164 patients with Parkinson's disease (PD) who underwent [(123)I]FP-CIT SPECT. Nuclear-medicine specialists evaluated the ...
Van Slambrouck Katrien - - 2014
Positron emission tomography (PET) data are typically reconstructed with maximum likelihood expectation maximization (MLEM). However, this method suffers from positive bias due to the non-negativity constraint. This is particularly problematic for tracer kinetic modeling analysis of dynamic PET studies. Two reconstruction methods with bias reduction properties that do not use ...
Nagy Peter P Department of Biophysics and Cell Biology, University of Debrecen, Debrecen, - - 2014
Ratiometric determination of the efficiency of fluorescence or Förster resonance energy transfer (FRET) is one of the most widespread methods for the characterization of protein clustering and conformation. Low photon numbers, often present in pixel-by-pixel determination of FRET efficiency in digital microscopy, result in large uncertainties in the derived FRET ...
Tian Hezhong - - 2014
Antimony (Sb) and its compounds are considered as global pollutants due to their health risks and long-range transport characteristics. A comprehensive global inventory of atmospheric antimony emissions from anthropogenic activities during the period of 1995-2010 has been developed with specific estimation methods based on the relevant data available for different ...
Vafi Kourosh - - 2014
Regulations on greenhouse gas (GHG) emissions from liquid fuel production generally work with incomplete data about oil production operations. We study the effect of incomplete information on estimates of GHG emissions from oil production operations. Data from California oil fields are used to generate probability distributions for eight oilfield parameters ...
Qiu Bingwen B National Engineering Research Centre of Geospatial Information Technology, Spatial Information Research Centre of Fujian Province, Fuzhou University, Science Building, 13th floor, Gongye Road 523, Fuzhou, 350002, Fujian, China, - - 2014
This paper develops a new crop mapping method through combined utilization of both time and frequency information based on wavelet variance and Jeffries-Matusita (JM) distance (CIWJ for short). A two-dimensional wavelet spectrum was obtained from datasets of daily continuous vegetation indices through a continuous wavelet transform using the Mexican hat ...
Yumimoto Keiya K Meteorological Research Institute, Japan Meteorological Agency, Nagamine 1-1, Tsukuba, Ibaraki 305-0032, Japan. Electronic address: - - 2014
Carbon monoxide (CO) emissions in China in 2005-2010 were estimated by inversion, using the Green's function method from vertical CO profiles derived from MOPITT Version 5 satellite data and a tagged CO simulation, and validated with independent in situ observations from the World Data Centre for Greenhouse Gases. Modeling with ...
Appling Alison P AP Nicholas School of the Environment, Duke University, Durham, North Carolina - - 2014
Abstract Nutrients in the environment are coupled over broad timescales (days to seasons) when organisms add or withdraw multiple nutrients simultaneously and in ratios that are roughly constant. But at finer timescales (seconds to days), nutrients become decoupled if physiological traits such as nutrient storage limits, circadian rhythms, or enzyme ...
Saquing Jovita M JM Department of Civil and Environmental Engineering, University of Delaware, 301 DuPont Hall, Newark, DE 19716, USA. Electronic address: - - 2014
The non-methane organic compound (NMOC) emission rate is used to assess compliance with landfill gas emission regulations by the United States Environmental Protection Agency (USEPA). A recent USEPA Report (EPA/600/R-11/033) employed a ratio method to estimate speciated NMOC emissions (i.e., individual NMOC emissions): speciated NMOC emissions=measured methane (CH4) emission multiplied ...
Li Rui R Pfizer - - 2014
A previously developed physiologically based pharmacokinetic (PBPK) model for hepatic transporter substrates was extended to an organic anion transporting polypeptide (OATP) substrate, telmisartan. Predictions utilized in vitro data from sandwich culture human hepatocyte (SCHH) and human liver microsome (HLM) assays. We have developed a novel method to calibrate partition coefficients ...
Zonta Zivko J - - 2014
The procedure commonly used for the assessment of the parameters included in activated sludge models (ASMs) relies on the estimation of their optimal value within a confidence region (i.e. frequentist inference). Once optimal values are estimated, parameter uncertainty is computed through the covariance matrix. However, alternative approaches based on the ...
Zhu Caigang C Singapore From the Division of Bioengineering, School of Chemical and Biomedical Engineering, Nanyang Technological University; and the Department of Plastic, Reconstructive and Aesthetic Surgery, Singapore General - - 2014
Accurate and early prediction of skin flap viability is vitally important in reconstructive surgery. To the best of the authors' knowledge, this is the first pilot study to evaluate the simultaneous use of both visible diffuse reflectance and autofluorescence spectroscopy on a reverse MacFarlane rat dorsal skin flap model in ...
Acevedo B B Instituto de Ingeniería del Agua y Medio Ambiente, Universitat Politècnica de València, Camino de Vera s/n, 46022 Valencia, Spain. Electronic address: - - 2014
Enhanced biological phosphorus removal (EBPR) is one of the most important methods of phosphorus removal in municipal wastewater treatment plants, having been described by different modelling approaches. In this process, the PAOs (polyphosphate accumulating organisms) and GAOs (glycogen accumulating organisms) compete for volatile fatty acids uptake under anaerobic conditions. Recent ...
Angelis Georgios I GI Faculty of Health Sciences and Brain and Mind Research Institute, The University of Sydney, Sydney, NSW, 2006, Australia, - - 2014
Estimation of nonlinear micro-parameters is a computationally demanding and fairly challenging process, since it involves the use of rather slow iterative nonlinear fitting algorithms and it often results in very noisy voxel-wise parametric maps. Direct reconstruction algorithms can provide parametric maps with reduced variance, but usually the overall reconstruction is ...
Muntean Marilena M European Commission, Joint Research Centre, Institute for Environment and Sustainability, Ispra, Italy. Electronic address: - - 2014
The Emission Database for Global Atmospheric Research (EDGAR) provides a time-series of man-made emissions of greenhouse gases and short-lived atmospheric pollutants from 1970 to 2008. Mercury is included in EDGARv4.tox1, thereby enriching the spectrum of multi-pollutant sources in the database. With an average annual growth rate of 1.3% since 1970, ...
T'jollyn Huybrecht H Laboratory of Medical Biochemistry and Clinical Analysis, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, - - 2014
To predict the tramadol in vivo pharmacokinetics in adults by using in vitro metabolism data and an in vitro-in vivo extrapolation (IVIVE)-linked physiologically-based pharmacokinetic (PBPK) modeling and simulation approach (Simcyp®). Tramadol metabolism data was gathered using metabolite formation in human liver microsomes (HLM) and recombinant enzyme systems (rCYP). Hepatic intrinsic ...
Pieralice Francesca F ISPRA (Institute for Environmental Protection and Research), via V. Brancati, 48, Rome, Italy. Electronic address: - - 2014
The Marine Strategy Framework Directive (MSFD, 2008/56/EC) is focused on protection, preservation and restoration of the marine environment by achieving and maintaining Good Environmental Status (GES) by 2020. Within this context, this paper presents a methodological approach for a fast and repeatable monitoring that allows quantitative assessment of seabed abrasion ...
Simonov Alexandr Nikolaevich - - 2014
Many electrode processes that approach the 'reversible' (infinitely fast) limit under voltammetric conditions have been inappropriately analysed by comparison of experimental data and theory derived from the 'quasi-reversible' model. Simulations based on 'reversible' and 'quasi-reversible' models have been fitted to an extensive series of a.c. voltammetric experiments undertaken at macrodisk ...
Lang Jianlei J Key Laboratory of Beijing on Regional Air Pollution Control, Beijing University of Technology, Beijing 100124, - - 2014
The on-road vehicular emission in China from 1999 to 2011 was estimated, based on the emission factors of vehicles with different emission standards calculated by the COPERT model. The CO, NMVOC, NOX, BC and OC emissions changed from 19.7 Tg, 4.4 Tg, 2.3 Tg, 47.1 Gg and 74.4 Gg in ...
van Velden Floris H P FH Department of Radiology & Nuclear Medicine, VU University Medical Center, PO Box 7057, 1007 MB, Amsterdam, The Netherlands, - - 2014
This study was conducted to directly compare the high-resolution research tomograph (HRRT) (high-resolution brain) and HR+ (standard whole-body) positron emission tomography (PET) only scanners for quantitative brain studies using three tracers with vastly different tracer distributions. Healthy volunteers underwent successive scans on HR+ and HRRT scanners (in random order) using ...
Majkut Joseph D JD Atmospheric and Oceanic Sciences Program, Department of Geosciences, Princeton University, Princeton, NJ 08544, USA - - 2014
The Southern Ocean is critically important to the oceanic uptake of anthropogenic CO2. Up to half of the excess CO2 currently in the ocean entered through the Southern Ocean. That uptake helps to maintain the global carbon balance and buffers transient climate change from fossil fuel emissions. However, the future ...
Jambor Ivan I Department of Diagnostic Radiology, University of Turku, Turku, - - 2014
To evaluate monoexponential, stretched exponential, kurtosis, and biexponential models for diffusion-weighted imaging (DWI) of normal prostate and prostate cancer (PCa), using b-values up to 2000 s/mm(2) , in terms of fitting quality and repeatability. Eight healthy volunteers and 16 PCa patients underwent a total of four repeated 3T DWI examinations ...
Fransson Martin N MN Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden - - 2014
The health effects of low-level chronic exposure to cadmium are increasingly recognized. To improve the risk assessment, it is essential to know the relation between cadmium intake, body burden and biomarker levels of cadmium. We combined a physiologically-based toxicokinetic (PBTK) model for cadmium with a data set from healthy kidney ...
Dong Yongsheng - - 2014
Statistical modeling of wavelet subbands has frequently been used for image recognition and retrieval. However, traditional wavelets are unsuitable for use with images containing distributed discontinuities, such as edges. Shearlets are a newly developed extension of wavelets that are better suited to image characterization. Here, we propose novel texture classification ...
Allik Jüri J Department of Psychology, University of Tartu, Näituse 2, Tartu, 50409, Estonia, - - 2014
In a bull's-eye acuity task, we asked observers to identify in which direction, to the left or the right, a spot had been displaced from the center of a circle and-after that, in the same trial-to detect which of the two presented circles contained the displaced spot. Replicating our previous ...
Merisaari Harri H Department of Information Technology, University of Turku, Turku, Finland; Turku PET Centre, University of Turku, Turku, - - 2014
To find optimal b-value distributions for monoexponential, stretched exponential, kurtosis, and biexponential models of prostate cancer (PCa) diffusion-weighted imaging (DWI) using simulations and repeated DWI examinations. Simulations aiming to minimize estimation accuracy error were performed. Ten PCa patients underwent in total four repeated 3-tesla DWI examinations using 12 equally spaced ...
Minati Ludovico L Scientific Department, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy; MR-Lab, Center for Mind/Brain Science, University of Trento, Italy. Electronic address: - - 2014
An outstanding issue in graph-based analysis of resting-state functional MRI is choice of network nodes. Individual consideration of entire brain voxels may represent a less biased approach than parcellating the cortex according to pre-determined atlases, but entails establishing connectedness for 1(9)-1(11) links, with often prohibitive computational cost. Using a representative ...
Reid Matthew C - - 2014
Pit latrines are an important form of decentralized wastewater management, providing hygienic and low-cost sanitation for approximately one-quarter of the global population. Latrines are also major sources of the greenhouse gas methane (CH4) from the anaerobic decomposition of organic matter in pits. In this study we develop a spatially-explicit approach ...
Ingrao Carlo C Department of Industrial Engineering, University of Catania, Viale A. Doria 6, 95125 Catania, Italy. Electronic address: - - 2014
A screening of Life Cycle Assessment for the evaluation of the damage arising from the production of 1 kg of recycled Polyethylene Terephthalate (RPET) fibre-based panel for building heat insulation was carried out according to the ISO 14040:2006 and 14044:2006. All data used were collected on site based on observations ...
Hasheminassab Sina S University of Southern California, Department of Civil and Environmental Engineering, Los Angeles, CA, - - 2014
Positive Matrix Factorization (PMF) was utilized to quantify sources of ambient PM2.5 in central Los Angeles (LA) and Rubidoux, using the Speciation Trends Network data, collected between 2002 and 2013. Vehicular emissions (including gasoline and diesel vehicles) were the second major contributor to PM2.5, following secondary aerosols, with about 20% ...
Wilks Moses Q MQ Department of Biomathematics, David Geffen School of Medicine at the University of California-Los Angeles, Los Angeles, California; and Department of Molecular and Medical Pharmacology, David Geffen School of Medicine the University of California-Los Angeles, Los Angeles, California - - 2014
Large-molecule tracers, such as labeled antibodies, have shown success in immuno-PET for imaging of specific cell surface biomarkers. However, previous work has shown that localization of such tracers shows high levels of heterogeneity in target tissues, due to both the slow diffusion and the high affinity of these compounds. In ...
Ni Mingjiang M State Key Laboratory of Clean Energy Utilization, Institute for Thermal Power Engineering, Zhejiang University, Hangzhou 310027, - - 2014
Black carbon (BC) produced from open burning (OB) and controlled combustion (CC) is a range of carbonaceous products of incomplete combustion of biomass and fossil fuel, and is deemed as one of the major contributors to impact global environment and human health. BC has a strong relationship with POPs, in ...
Zhu Xiaozhang - - 2014
To improve the model-based inversion performance of microwave induced thermoacoustic tomography for breast tumor imaging, an active adjoint modeling (AAM) method is proposed. It aims to provide a more realistic breast acoustic model used for tumor inversion as the background by actively measuring and reconstructing the structural heterogeneity of human ...
Than Trung Duc TD School of Mechanical, Materials and Mechatronic Engineering, University of Wollongong, New South Wales 2522, - - 2014
Over the last decade, wireless capsule endoscope has been the tool of choice for noninvasive inspection of the gastrointestinal tract, especially in the small intestine. However, the latest clinical products have not been equipped with a sufficiently accurate localization system which makes it difficult to determine the location of intestinal ...
Abdel-Aal M M School of Engineering Design and Technology, University of Bradford, BD7 1PD, UK E-mail: - - 2014
Modelling of wastewater temperatures along a sewer pipe using energy balance equations and assuming steady-state conditions was achieved. Modelling error was calculated, by comparing the predicted temperature drop to measured ones in three combined sewers, and was found to have an overall root mean squared error of 0.37 K. Downstream ...
Vijayaraghavan Krish - - 2014
On-road vehicle emissions of carbon monoxide (CO), nitrogen oxides (NO(x)), and volatile organic compounds (VOCs) during 1995-2009 in the Atlanta Metropolitan Statistical Area were estimated using the Motor Vehicle Emission Simulator (MOVES) model and data from the National Emissions Inventories and the State of Georgia. Statistically significant downward trends (computed ...
Majumdar Dipanjali - - 2014
Surface emission from Dhapa, the only garbage disposal ground in Kolkata, is a matter of concern to the local environment and also fuels the issues of occupational and environmental health. Surface emission of the Dhapa landfill site was studied using a flux chamber measurement for nonmethane volatile organic compounds (NMVOCs). ...
Sun Zhan-Li - - 2014
The reliable and accurate identification of cancer categories is crucial to a successful diagnosis and a proper treatment of the disease. In most existing work, samples of gene expression data are treated as one-dimensional signals, and are analyzed by means of some statistical signal processing techniques or intelligent computation algorithms. ...
Müller J J Centre for Mathematical Sciences, TU München, Boltzmannstraße 3, D-85758 Garching, Germany; Institute of Computational Biology, Helmholtzzentrum München, D-85764 Neuherberg, Germany. Electronic address: - - 2014
We consider the uptake of various carbon sources by microorganisms based on four fundamental assumptions: (1) the uptake of nutrient follows a saturation characteristics (2) substrate processing has a benefit but comes at costs of maintaining the process chain (3) substrate uptake is controlled and (4) evolution optimized the control ...
Glaser Alexander A Department of Mechanical and Aerospace Engineering, Princeton University, E-Quad, Olden Street, Princeton, New Jersey 08544, - - 2014
The verification of nuclear warheads for arms control involves a paradox: international inspectors will have to gain high confidence in the authenticity of submitted items while learning nothing about them. Proposed inspection systems featuring 'information barriers', designed to hide measurements stored in electronic systems, are at risk of tampering and ...
Garcia-Menendez Fernando F School of Civil and Environmental Engineering, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, GA 30332, USA. Electronic address: - - 2014
Air quality forecasts generated with chemical transport models can provide valuable information about the potential impacts of fires on pollutant levels. However, significant uncertainties are associated with fire-related emission estimates as well as their distribution on gridded modeling domains. In this study, we explore the sensitivity of fine particulate matter ...
Zhou Feng - - 2014
The amount and geographic distribution of N2O emissions over China remain largely uncertain. In this study, county-level and 0.1×°0.1° gridded anthropogenic N2O emission inventories for China (PKU-N2O) in 2008 are developed based on high-resolution activity data and regional emission factors (EFs) and parameters. These new estimates are compared with previous ...
Laffon E E CHU de Bordeaux, Service de Médecine Nucléaire, F-33604 Pessac, France; Université de Bordeaux 2, Centre de Recherche Cardio-Thoracique, F-33076 Bordeaux, France; INSERM U 1045, Centre de Recherche Cardio-Thoracique, F-33076 Bordeaux, France. Electronic address: - - 2014
It is known that for a fixed amount of injected tracer, the amount available for a tissue of interest will be less if other tissues show intense uptake. The aim of this study was to estimate the magnitude of 2-deoxy-2-[(18)F]fluoro-d-glucose (18FDG) uptake amount in physiological tissues that may show an ...
Batool Nazre - - 2014
Facial retouching is widely used in media and entertainment industry. Professional software usually require a minimum level of user expertise to achieve the desirable results. In this paper, we present an algorithm to detect facial wrinkles/imperfection. We believe that any such algorithm would be amenable to facial retouching applications. The ...
Yan H H HH Air Quality Studies, Department of Civil and Environmental Engineering, The Hong Kong Polytechnic University, Hong - - 2014
During the implementation of Montreal Protocol, emission inventories of halocarbons in different sectors at regional scale are fundamental to the formulation of relevant management strategy and inspection of the implementation efficiency. This study investigated the emission profile of halocarbons used in the mobile vehicle air conditioning system, the leading sector ...
White Lee C LC Department of Psychology, Swansea University, United Kingdom. Electronic address: - - 2014
Decisions can sometimes have a constructive role, so that the act of, for example, choosing one option over another creates a preference for that option (e.g., Ariely & Norton, 2008; Payne, Bettman, & Johnson, 1993; Sharot, Velasquez, & Dolan, 2010; Sherman, 1980). In this work we explore the constructive role ...
1 2 3 4 5 6 7 8 9 10 >