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Poludniowski G G Centre for Vision Speech and Signal Processing, University of Surrey, Guildford, GU2 7XH, - - 2014
A novel approach to proton CT reconstruction using backprojection-then-filtering (BPF) is proposed. A list-mode algorithm is formulated accommodating non-linear proton paths. The analytical form is derived for the deblurring kernel necessary for the filtering step. Further, a finite matrix correction is derived to correct for the limited size of the ...
McGuire Alan B AB Roudebush VA Medical Center, Indianapolis, IN, USA, - - 2014
This study examined three methodological approaches to defining the critical elements of Illness Management and Recovery (IMR), a curriculum-based approach to recovery. Sixty-seven IMR experts rated the criticality of 16 IMR elements on three dimensions: defining, essential, and impactful. Three elements (Recovery Orientation, Goal Setting and Follow-up, and IMR Curriculum) ...
Baran Michael M M. Baran, PhD Candidate, School of Arts Media and Engineering, Arizona State University, PO Box 878709, Tempe, AZ 85287 - - 2014
Interactive neurorehabilitation (INR) systems provide therapy that can evaluate and deliver feedback on a patient's movement computationally. There are currently many approaches to INR design and implementation, without a clear indication of which methods to utilize best. We present key interactive computing, motor learning and media arts concepts utilized by ...
Lubell Yoel - - 2014
Artemisinin combination therapy is recommended as first-line treatment for falciparum malaria across the endemic world and is increasingly relied upon for treating vivax malaria where chloroquine is failing. Artemisinin resistance was first detected in western Cambodia in 2007, and is now confirmed in the Greater Mekong region, raising the spectre ...
Pinto M M IPNL, Université de Lyon, F-69003 Lyon, France; Université Lyon 1, F-69622 Villeurbanne, France; CNRS/IN2P3, UMR 5822 F-69622 Villeurbanne, - - 2014
Hadrontherapy is an innovative radiation therapy modality for which one of the main key advantages is the target conformality allowed by the physical properties of ion species. However, in order to maximise the exploitation of its potentialities, online monitoring is required in order to assert the treatment quality, namely monitoring ...
Watanabe Noriko - - 2014
Insecticide-treated nets (ITNs) are an integral piece of any malaria elimination strategy, but compliance remains a challenge and determinants of use vary by location and context. The Health Belief Model (HBM) is a tool to explore perceptions and beliefs about malaria and ITN use. Insights from the model can be ...
Li Qiuju Q School of Mathematics, The University of Manchester, - - 2014
In medical studies, repeated measurements of continuous, binary and ordinal outcomes are routinely collected from the same patient. Instead of modelling each outcome separately, in this study we propose to jointly model the trivariate longitudinal responses, so as to take account of the inherent association between the different outcomes and ...
Tronstad Lund Marianne - - 2014
Biofuels are proposed to play an important role in several mitigation strategies to meet future CO2 emission targets for the transport sector, but remain controversial due to significant uncertainties in net impacts on environment, society and climate. A switch to biofuels can also affect short-lived climate forcers (SLCFs), which provide ...
Wu Jinglan J State Key Laboratory of Materials-Oriented Chemical Engineering, Nanjing, 210009, P. R. China; College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing, 210009, P. R. China; National Engineering Technique Research Center for Biotechnology, Nanjing, 211816, P. R. - - 2014
Separation of butanol based on sorption methodology from Acetone - Butanol - Ethanol (ABE) fermentation broth has advantages in terms of biocompatibility and stability, as well as economy, and therefore gains much attention. In this work a chromatographic column model based on the solid film linear driving force approach and ...
Hwang Wen-Han WH Institute of Statistics and Department of Applied Mathematics, National Chung Hsing University, Taichung 40227, - - 2014
Good-Turing frequency estimation (Good, ) is a simple, effective method for predicting detection probabilities of objects of both observed and unobserved classes based on observed frequencies of classes in a sample. The method has been used widely in several disciplines, such as information retrieval, computational linguistics, text recognition, and ecological ...
Gan Sonny - - 2014
Spectral clustering involves placing objects into clusters based on the eigenvectors and eigenvalues of an associated matrix. The technique was first applied to molecular data by Brewer [J. Chem. Inf. Modell. 47,1727-1733 (2007)] who demonstrated its use on a very small dataset of 125 COX-2 inhibitors. We have determined suitable ...
Metyko John J *Department of Environmental Health and Safety, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030-4009; †Department of Imaging Physics Department, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX - - 2014
Three different Y internally-administered radionuclide therapies are currently used in both standard-of-care and clinical trial procedures at MD Anderson Cancer Center. TheraSphere and SIR-Spheres therapies utilize Y-labeled microspheres, while Zevalin is an Y-labeled radioimmunotherapeutic agent. Several publications have indicated radionuclidic impurities resulting from Y production methods. The Y in SIR-Spheres ...
Harding R R St James's Institute of Oncology, Medical Physics and Engineering, Leeds LS9 7TF, United Kingdomand Abertawe Bro Morgannwg University Health Board, Medical Physics and Clinical Engineering, Swansea SA2 8QA, United - - 2014
Base of skull meningioma can be treated with both intensity modulated radiation therapy (IMRT) and spot scanned proton therapy (PT). One of the main benefits of PT is better sparing of organs at risk, but due to the physical and dosimetric characteristics of protons, spot scanned PT can be more ...
De Bin Riccardo - - 2014
In the last years, the importance of independent validation of the prediction ability of a new gene signature has been largely recognized. Recently, with the development of gene signatures which integrate rather than replace the clinical predictors in the prediction rule, the focus has been moved to the validation of ...
Zhang Xinke X Department of Clinical Pharmacy and Pharmaceutical Economics and Policy, Leonard D. Schaeffer Center for Health Policy and Economics, University of Southern California, University Park Campus, VPD 214-L, Los Angeles, CA, 90089-3333, - - 2014
The aim of the study was to compare the cost effectiveness of fingolimod, teriflunomide, dimethyl fumarate, and intramuscular (IM) interferon (IFN)-β1a as first-line therapies in the treatment of patients with relapsing-remitting multiple sclerosis (RRMS). A Markov model was developed to evaluate the cost effectiveness of disease-modifying drugs (DMDs) from a ...
Hu En-Liang - - 2014
Nonparametric kernel learning (NPKL) is a flexible approach to learn the kernel matrix directly without assuming any parametric form. It can be naturally formulated as a semidefinite program (SDP), which, however, is not very scalable. To address this problem, we propose the combined use of low-rank approximation and block coordinate ...
Ditty Matthew S MS The Ebright Foundation, LLC, 2800 Lancaster Ave., Suite 6, Wilmington, DE, 19810, USA, - - 2014
Guided by the Consolidated Framework for Implementation Research, this mixed method study explored the relationship between inner setting variables and dialectical behavior therapy (DBT) implementation. Intensively trained DBT clinicians completed an online quantitative survey (n = 79) and a subset were sequentially interviewed using qualitative methods (n = 20) to identify relationships between inner ...
Kona Ravikanth R School of Pharmacy, University of Maryland, 20 N. Pine Street, Baltimore, Maryland, 21201, - - 2014
The objective of this study is to use near-infrared spectroscopy (NIRS) coupled with multivariate chemometric models to monitor granule and tablet quality attributes in the formulation development and manufacturing of ciprofloxacin hydrochloride (CIP) immediate release tablets. Critical roller compaction process parameters, compression force (CFt), and formulation variables identified from our ...
Nascimento Jacinto - - 2014
This paper proposes an iterative natural gradient algorithm to perform the optimization of switching probabilities in a space-varying HMM, in the context of human activity recognition in long-range surveillance. The proposed method is a version of the gradient method, developed under an information geometric viewpoint, where the usual Euclidean metric ...
Simundic Ana-Maria - - 2014
Abstract At least one in 10 patients experience adverse events while receiving hospital care. Many of the errors are related to laboratory diagnostics. Efforts to reduce laboratory errors over recent decades have primarily focused on the measurement process while pre- and post-analytical errors including errors in sampling, reporting and decision-making ...
Lee Xing Ju XJ School of Mathematical Sciences, Queensland University of Technology, Brisbane, Queensland, 4000, - - 2014
Analytically or computationally intractable likelihood functions can arise in complex statistical inferential problems making them inaccessible to standard Bayesian inferential methods. Approximate Bayesian computation (ABC) methods address such inferential problems by replacing direct likelihood evaluations with repeated sampling from the model. ABC methods have been predominantly applied to parameter estimation ...
Carson-Wong Amanda A a Department of Psychology , Rutgers University , Piscataway , NJ , - - 2014
Abstract Objective: There are six strategies or validation levels in dialectical behavior therapy (DBT), yet there are no measures designed to code for them. This absence limits our understanding of the relationship between validation strategies and treatment outcome. The DBT-Validation Level Coding Scale (DBT-VLCS) was developed to overcome this limitation. ...
Martin Johannes J E JJ MARTIN GmbH für Umwelt- und Energietechnik, Leopoldstrasse 248, 80807 München, - - 2014
Thermal treatment of waste by means of combustion in grate-based systems has gained world-wide acceptance as the preferred method for sustainable management and safe disposal of residual waste. In order to maintain this position and to address new challenges and/or priorities, these systems need to be further developed with a ...
Ament Jared D JD University of California, Davis, - - 2014
Cervical total disc replacement (CTDR) was developed to treat cervical spondylosis, while preserving motion. While anterior cervical discectomy and fusion (ACDF) has been the standard of care for 2-level disease, a randomized clinical trial (RCT) suggested similar outcomes. Cost-effectiveness of this intervention has never been elucidated. To determine the cost-effectiveness ...
Murray Carolyn C School of Health Sciences, International Centre for Allied Health Evidence, University of South Australia, Adelaide, South Australia, - - 2014
Growth in the number of occupational therapy programmes in Australia has resulted in a critical shortage of academics. When experienced clinicians are recruited into academia, they may find the transition process difficult. The study aimed to explore clinicians' perspectives of what happens when they transition into academia. A constructivist grounded ...
Biswas Subhodip - - 2014
In real life, we often need to find multiple optimally sustainable solutions of an optimization problem. Evolutionary multimodal optimization algorithms can be very helpful in such cases. They detect and maintain multiple optimal solutions during the run by incorporating specialized niching operations in their actual framework. Differential evolution (DE) is ...
Hummert Sabine S Fachhochschule Schmalkalden, Faculty of Electrical Engineering, Blechhammer, 98574 Schmalkalden, - - 2014
In two papers we review game theory applications in biology below the level of cognitive living beings. It can be seen that evolution and natural selection replace the rationality of the actors appropriately. Even in these micro worlds, competing situations and cooperative relationships can be found and modeled by evolutionary ...
Tindall B J BJ Leibniz Institute-DSMZ Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH., Inhoffenstrasse 7b, 38124 Braunschweig, Germany - - 2014
The Judicial Commission affirms that the COMBINATION: Micromonospora aurantiaca Sveshnikova et al. 1969 (Approved Lists 1980) may not serve as the CORRECT NAME: of the taxon because Rule 12b states that no SPECIFIC: or SUBSPECIFIC EPITHETS: within the same genus may be the same if based on different types and ...
Rafei Rayane R L'UNAM Université, Université d'Angers, Groupe d'Etude des Interactions Hôte-Pathogène, UPRES EA3142, Institut de Biologie en Santé - IRIS, CHU, 4, rue Larrey, 49933 Angers cedex, - - 2014
ABSTRACT  The emergence of Acinetobacter baumannii during recent decades as an important nosocomial pathogen responsible of worldwide, intensively documented, outbreaks has resulted in a need for effective epidemiological typing methods. Throughout the years, many typing methods for A. baumannii epidemiological studies have been proposed from phenotypic to molecular methods. Currently, ...
Li Bo B State Key Laboratory of Urban and Regional Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Shuangqing Road 18, Haidian District, Beijing 100085, - - 2014
Due to the rapid development of economy and technology, China has the biggest production and possession of mobile phones around the world. In general, mobile phones have relatively short life time because the majority of users replace their mobile phones frequently. Retired mobile phones represent the most valuable electrical and ...
Yao Deqiang D Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, People's Republic of - - 2014
A case study has been made on the treatment of the SIRAS (single isomorphous replacement with anomalous scattering) data of the originally unknown protein LegC3N. An alternative treatment has been proposed which led to improved results in this particular test case. The treatment involves iterative direct-method SAD (single-wavelength anomalous diffraction) ...
Seki Motohide M Faculty of Environmental Earth Science, Hokkaido University, N10W5, Kita-ku, Sapporo, Hokkaido, 060-0810, Japan, - - 2014
According to the viewpoint of the optimal strategy theory, a tree is expected to shed its leaves when they no longer contribute to maximisation of net carbon gain. Several theoretical models have been proposed in which a tree was assumed to strategically shed an old deteriorated leaf to develop a ...
Albano Giuseppina G Dip. di Scienze Economiche e Statistiche, Università di Salerno, Italy. Electronic address: - - 2014
A modified Gompertz diffusion process is considered to model tumor dynamics. The infinitesimal mean of this process includes non-homogeneous terms describing the effect of therapy treatments able to modify the natural growth rate of the process. Specifically, therapies with an effect on cell growth and/or cell death are assumed to ...
Cerveri Pietro P Department of Electronics, Information and Bioengineering, Politecnico di Milano, via Ponzio 34/5, 20133 Milano, Italy. Electronic address: - - 2014
Personalized resection guides (PRG) have been recently proposed in the domain of knee replacement, demonstrating clinical outcome similar or even superior to both manual and navigated interventions. Among the mandatory pre-surgical steps for PRG prototyping, the measurement of clinical landmarks (CL) on the bony surfaces is recognized as a key ...
Ternès Nils N aService biostatistique et épidémiologie, Gustave-Roussy, Villejuif, bUniversity Paris-Sud, Le Kremlin-Bicêtre cDépartement de médecine, Pathologie Mammaire, Gustave-Roussy, Villejuif, - - 2014
Omics technologies have become an essential part of clinical trials in oncology to provide a better understanding of molecular mechanisms and to unveil therapeutic targets. Standard statistical methods often fail in the high-dimensional setting. Therefore, an adequate modelling of the omics data is needed in order to identify 'target' genes ...
Grotzinger Andrew A Eating and Weight Disorders Program, Department of Psychiatry, Icahn School of Medicine, New York, New - - 2014
Change in binge eating is typically a primary outcome for interventions targeting individuals with eating pathology. A range of statistical models exist to handle these types of frequency distributions, but little empirical evidence exists to guide the appropriate choice of statistical model. Monte Carlo simulations were used to investigate the ...
Schaaf Roseann C RC Roseann C. Schaaf, PhD, OTR/L, FAOTA, is Professor and Chair, Department of Occupational Therapy, Jefferson School of Health Professions, Thomas Jefferson University, Philadelphia, PA, and Faculty, Farber Institute for Neurosciences, 901 Walnut Street, Suite 605, Philadelphia, PA 19107; - - 2014
This article presents the current state of measurement in the area of sensory integration within the field of occupational therapy in three areas: (1) phenotypic characterization, (2) intervention adherence and dosage, and (3) outcome measurement. The need for additional measurement tools in all three areas is addressed. In regard to ...
Harris Daniel R - - 2014
We present a custom, Boolean query generator utilizing common-table expressions (CTEs) that is capable of scaling with big datasets. The generator maps user-defined Boolean queries, such as those interactively created in clinical-research and general-purpose healthcare tools, into SQL. We demonstrate the effectiveness of this generator by integrating our study into ...
Green Christopher - - 2014
In the field of business continuity management, organisations commit sums of money (often very large sums) to develop and maintain their continuity capability. Despite this, there is almost no measurement of whether this expense offers value for money, or whether it is targeted in the right areas. This paper will ...
Phillipson Frank - - 2014
Business continuity professionals aim to mitigate the various challenges to the continuity of their company. The goal is a coherent system of measures that encompass detection, prevention and recovery. Choices made in one part of the system affect other parts as well as the continuity risks of the company. In ...
Hua Xijin X Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, Leeds, UK. Electronic address: - - 2014
Edge loading can negatively impact the biomechanics and long-term performance of hip replacements. Although edge loading has been widely investigated for hard-on-hard articulations, limited work has been conducted for hard-on-soft combinations. The aim of the present study was to investigate edge loading and its effect on the contact mechanics of ...
Toussaint Emmanuel F A EF SNSB-Bavarian State Collection of Zoology, Münchhausenstraße 21, 81247 Munich, Germany. - - 2014
During the Cenozoic, Australia experienced major climatic shifts that have had dramatic ecological consequences for the modern biota. Mesic tropical ecosystems were progressively restricted to the coasts and replaced by arid-adapted floral and faunal communities. Whilst the role of aridification has been investigated in a wide range of terrestrial lineages, ...
Ramgopal Sriram S Division of Epilepsy and Clinical Neurophysiology, Department of Neurology, Boston Children's Hospital, Boston, MA, USA; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, - - 2014
Nearly one-third of patients with epilepsy continue to have seizures despite optimal medication management. Systems employed to detect seizures may have the potential to improve outcomes in these patients by allowing more tailored therapies and might, additionally, have a role in accident and SUDEP prevention. Automated seizure detection and prediction ...
Yoon Ji Won JW Cyber Defense Department and Graduate School of Information Security, Korea University, South Korea. Electronic address: - - 2014
Projection reconstruction nuclear magnetic resonance (PR-NMR) is a technique for generating multidimensional NMR spectra. A small number of projections from lower-dimensional NMR spectra are used to reconstruct the multidimensional NMR spectra. In our previous work [1,2], it was shown that multidimensional NMR spectra are efficiently reconstructed using peak-by-peak based reversible ...
Zheng Liying L Department of Orthopedic Surgery, University of Pittsburgh, - - 2014
This manuscript presents a new subject-specific musculoskeletal dynamic modeling approach that integrates high-accuracy dynamic stereo-radiography (DSX) joint kinematics and surface-based full-body motion data. We illustrate this approach by building a model in OpenSim for a patient who participated in a meniscus transplantation efficacy study, incorporating DSX data of the tibiofemoral ...
Bowler Meghan A MA Department of Biomedical Engineering, Vanderbilt University, Nashville, TN - - 2014
Calcific aortic valve disease (CAVD) affects 25% of people over 65, and the late-stage stenotic state can only be treated with total valve replacement, requiring 85,000 surgeries annually in the US alone (University of Maryland Medical Center, 2013, http://umm.edu/programs/services/heart-center-programs/cardiothoracic-surgery/valve-surgery/facts). As CAVD is an age-related disease, many of the affected patients ...
Cuenca-Bescós Gloria G Research Group Aragosaurus-IUCA, Paleontology, Earth Sciences Department, University of Zaragoza, Zaragoza, - - 2014
The extant Cabrera's vole, Microtus cabrerae, differs in morphology and evolutionary history from the other species of Microtus. This arvicoline has unique derived features in the cranium, mandible and dentition. Probably its most conspicuous features are its large size, the high skull in lateral view, the long and distally broad ...
Chi Eric C EC Department of Human Genetics, University of California, Los Angeles, CA 90095, - - 2014
The problem of minimizing a continuously differentiable convex function over an intersection of closed convex sets is ubiquitous in applied mathematics. It is particularly interesting when it is easy to project onto each separate set, but nontrivial to project onto their intersection. Algorithms based on Newton's method such as the ...
Brodie Jedediah F JF Departments of Zoology & Botany, Biodiversity Research Centre, University of British Columbia, 3529-6270 University Blvd, Vancouver, British Columbia, V6T 1Z4, Canada. - - 2014
Habitat corridors are important tools for maintaining connectivity in increasingly fragmented landscapes, but generally they have been considered in single-species approaches. Corridors intended to facilitate the movement of multiple species could increase persistence of entire communities, but at the likely cost of being less efficient for any given species than ...
Lee Hsiang-Ming HM 1 Department of Business and Management Chien Hsin University of Science and Technology, - - 2014
Summary.-This study examined the role of enjoyment in people's decision to barter online. A survey in barter BBS/discussion forums and websites collected data from 135 participants (30 men, 105 women; 71% in the age group of 21-30 years) who barter online. To test a modification of the Expectation Confirmation Model, ...
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