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Metyko John J *Department of Environmental Health and Safety, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030-4009; †Department of Imaging Physics Department, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX - - 2014
Three different Y internally-administered radionuclide therapies are currently used in both standard-of-care and clinical trial procedures at MD Anderson Cancer Center. TheraSphere and SIR-Spheres therapies utilize Y-labeled microspheres, while Zevalin is an Y-labeled radioimmunotherapeutic agent. Several publications have indicated radionuclidic impurities resulting from Y production methods. The Y in SIR-Spheres ...
Zhang Xinke X Department of Clinical Pharmacy and Pharmaceutical Economics and Policy, Leonard D. Schaeffer Center for Health Policy and Economics, University of Southern California, University Park Campus, VPD 214-L, Los Angeles, CA, 90089-3333, - - 2014
The aim of the study was to compare the cost effectiveness of fingolimod, teriflunomide, dimethyl fumarate, and intramuscular (IM) interferon (IFN)-β1a as first-line therapies in the treatment of patients with relapsing-remitting multiple sclerosis (RRMS). A Markov model was developed to evaluate the cost effectiveness of disease-modifying drugs (DMDs) from a ...
Ditty Matthew S MS The Ebright Foundation, LLC, 2800 Lancaster Ave., Suite 6, Wilmington, DE, 19810, USA, - - 2014
Guided by the Consolidated Framework for Implementation Research, this mixed method study explored the relationship between inner setting variables and dialectical behavior therapy (DBT) implementation. Intensively trained DBT clinicians completed an online quantitative survey (n = 79) and a subset were sequentially interviewed using qualitative methods (n = 20) to identify relationships between inner ...
Kona Ravikanth R School of Pharmacy, University of Maryland, 20 N. Pine Street, Baltimore, Maryland, 21201, - - 2014
The objective of this study is to use near-infrared spectroscopy (NIRS) coupled with multivariate chemometric models to monitor granule and tablet quality attributes in the formulation development and manufacturing of ciprofloxacin hydrochloride (CIP) immediate release tablets. Critical roller compaction process parameters, compression force (CFt), and formulation variables identified from our ...
Nascimento Jacinto - - 2014
This paper proposes an iterative natural gradient algorithm to perform the optimization of switching probabilities in a space-varying HMM, in the context of human activity recognition in long-range surveillance. The proposed method is a version of the gradient method, developed under an information geometric viewpoint, where the usual Euclidean metric ...
Simundic Ana-Maria - - 2014
Abstract At least one in 10 patients experience adverse events while receiving hospital care. Many of the errors are related to laboratory diagnostics. Efforts to reduce laboratory errors over recent decades have primarily focused on the measurement process while pre- and post-analytical errors including errors in sampling, reporting and decision-making ...
Lee Xing Ju XJ School of Mathematical Sciences, Queensland University of Technology, Brisbane, Queensland, 4000, - - 2014
Analytically or computationally intractable likelihood functions can arise in complex statistical inferential problems making them inaccessible to standard Bayesian inferential methods. Approximate Bayesian computation (ABC) methods address such inferential problems by replacing direct likelihood evaluations with repeated sampling from the model. ABC methods have been predominantly applied to parameter estimation ...
Carson-Wong Amanda A a Department of Psychology , Rutgers University , Piscataway , NJ , - - 2014
Abstract Objective: There are six strategies or validation levels in dialectical behavior therapy (DBT), yet there are no measures designed to code for them. This absence limits our understanding of the relationship between validation strategies and treatment outcome. The DBT-Validation Level Coding Scale (DBT-VLCS) was developed to overcome this limitation. ...
Martin Johannes J E JJ MARTIN GmbH für Umwelt- und Energietechnik, Leopoldstrasse 248, 80807 München, - - 2014
Thermal treatment of waste by means of combustion in grate-based systems has gained world-wide acceptance as the preferred method for sustainable management and safe disposal of residual waste. In order to maintain this position and to address new challenges and/or priorities, these systems need to be further developed with a ...
Ament Jared D JD University of California, Davis, - - 2014
Cervical total disc replacement (CTDR) was developed to treat cervical spondylosis, while preserving motion. While anterior cervical discectomy and fusion (ACDF) has been the standard of care for 2-level disease, a randomized clinical trial (RCT) suggested similar outcomes. Cost-effectiveness of this intervention has never been elucidated. To determine the cost-effectiveness ...
Murray Carolyn C School of Health Sciences, International Centre for Allied Health Evidence, University of South Australia, Adelaide, South Australia, - - 2014
Growth in the number of occupational therapy programmes in Australia has resulted in a critical shortage of academics. When experienced clinicians are recruited into academia, they may find the transition process difficult. The study aimed to explore clinicians' perspectives of what happens when they transition into academia. A constructivist grounded ...
Biswas Subhodip - - 2014
In real life, we often need to find multiple optimally sustainable solutions of an optimization problem. Evolutionary multimodal optimization algorithms can be very helpful in such cases. They detect and maintain multiple optimal solutions during the run by incorporating specialized niching operations in their actual framework. Differential evolution (DE) is ...
Hummert Sabine S Fachhochschule Schmalkalden, Faculty of Electrical Engineering, Blechhammer, 98574 Schmalkalden, - - 2014
In two papers we review game theory applications in biology below the level of cognitive living beings. It can be seen that evolution and natural selection replace the rationality of the actors appropriately. Even in these micro worlds, competing situations and cooperative relationships can be found and modeled by evolutionary ...
Tindall B J BJ Leibniz Institute-DSMZ Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH., Inhoffenstrasse 7b, 38124 Braunschweig, Germany - - 2014
The Judicial Commission affirms that the COMBINATION: Micromonospora aurantiaca Sveshnikova et al. 1969 (Approved Lists 1980) may not serve as the CORRECT NAME: of the taxon because Rule 12b states that no SPECIFIC: or SUBSPECIFIC EPITHETS: within the same genus may be the same if based on different types and ...
Li Bo B State Key Laboratory of Urban and Regional Ecology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Shuangqing Road 18, Haidian District, Beijing 100085, - - 2014
Due to the rapid development of economy and technology, China has the biggest production and possession of mobile phones around the world. In general, mobile phones have relatively short life time because the majority of users replace their mobile phones frequently. Retired mobile phones represent the most valuable electrical and ...
Yao Deqiang D Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, People's Republic of - - 2014
A case study has been made on the treatment of the SIRAS (single isomorphous replacement with anomalous scattering) data of the originally unknown protein LegC3N. An alternative treatment has been proposed which led to improved results in this particular test case. The treatment involves iterative direct-method SAD (single-wavelength anomalous diffraction) ...
Seki Motohide M Faculty of Environmental Earth Science, Hokkaido University, N10W5, Kita-ku, Sapporo, Hokkaido, 060-0810, Japan, - - 2014
According to the viewpoint of the optimal strategy theory, a tree is expected to shed its leaves when they no longer contribute to maximisation of net carbon gain. Several theoretical models have been proposed in which a tree was assumed to strategically shed an old deteriorated leaf to develop a ...
Albano Giuseppina G Dip. di Scienze Economiche e Statistiche, Università di Salerno, Italy. Electronic address: - - 2014
A modified Gompertz diffusion process is considered to model tumor dynamics. The infinitesimal mean of this process includes non-homogeneous terms describing the effect of therapy treatments able to modify the natural growth rate of the process. Specifically, therapies with an effect on cell growth and/or cell death are assumed to ...
Cerveri Pietro P Department of Electronics, Information and Bioengineering, Politecnico di Milano, via Ponzio 34/5, 20133 Milano, Italy. Electronic address: - - 2014
Personalized resection guides (PRG) have been recently proposed in the domain of knee replacement, demonstrating clinical outcome similar or even superior to both manual and navigated interventions. Among the mandatory pre-surgical steps for PRG prototyping, the measurement of clinical landmarks (CL) on the bony surfaces is recognized as a key ...
Ternès Nils N aService biostatistique et épidémiologie, Gustave-Roussy, Villejuif, bUniversity Paris-Sud, Le Kremlin-Bicêtre cDépartement de médecine, Pathologie Mammaire, Gustave-Roussy, Villejuif, - - 2014
Omics technologies have become an essential part of clinical trials in oncology to provide a better understanding of molecular mechanisms and to unveil therapeutic targets. Standard statistical methods often fail in the high-dimensional setting. Therefore, an adequate modelling of the omics data is needed in order to identify 'target' genes ...
Grotzinger Andrew A Eating and Weight Disorders Program, Department of Psychiatry, Icahn School of Medicine, New York, New - - 2014
Change in binge eating is typically a primary outcome for interventions targeting individuals with eating pathology. A range of statistical models exist to handle these types of frequency distributions, but little empirical evidence exists to guide the appropriate choice of statistical model. Monte Carlo simulations were used to investigate the ...
Schaaf Roseann C RC Roseann C. Schaaf, PhD, OTR/L, FAOTA, is Professor and Chair, Department of Occupational Therapy, Jefferson School of Health Professions, Thomas Jefferson University, Philadelphia, PA, and Faculty, Farber Institute for Neurosciences, 901 Walnut Street, Suite 605, Philadelphia, PA 19107; - - 2014
This article presents the current state of measurement in the area of sensory integration within the field of occupational therapy in three areas: (1) phenotypic characterization, (2) intervention adherence and dosage, and (3) outcome measurement. The need for additional measurement tools in all three areas is addressed. In regard to ...
Harris Daniel R - - 2014
We present a custom, Boolean query generator utilizing common-table expressions (CTEs) that is capable of scaling with big datasets. The generator maps user-defined Boolean queries, such as those interactively created in clinical-research and general-purpose healthcare tools, into SQL. We demonstrate the effectiveness of this generator by integrating our study into ...
Green Christopher - - 2014
In the field of business continuity management, organisations commit sums of money (often very large sums) to develop and maintain their continuity capability. Despite this, there is almost no measurement of whether this expense offers value for money, or whether it is targeted in the right areas. This paper will ...
Phillipson Frank - - 2014
Business continuity professionals aim to mitigate the various challenges to the continuity of their company. The goal is a coherent system of measures that encompass detection, prevention and recovery. Choices made in one part of the system affect other parts as well as the continuity risks of the company. In ...
Hua Xijin X Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, Leeds, UK. Electronic address: - - 2014
Edge loading can negatively impact the biomechanics and long-term performance of hip replacements. Although edge loading has been widely investigated for hard-on-hard articulations, limited work has been conducted for hard-on-soft combinations. The aim of the present study was to investigate edge loading and its effect on the contact mechanics of ...
Toussaint Emmanuel F A EF SNSB-Bavarian State Collection of Zoology, Münchhausenstraße 21, 81247 Munich, Germany. - - 2014
During the Cenozoic, Australia experienced major climatic shifts that have had dramatic ecological consequences for the modern biota. Mesic tropical ecosystems were progressively restricted to the coasts and replaced by arid-adapted floral and faunal communities. Whilst the role of aridification has been investigated in a wide range of terrestrial lineages, ...
Ramgopal Sriram S Division of Epilepsy and Clinical Neurophysiology, Department of Neurology, Boston Children's Hospital, Boston, MA, USA; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, - - 2014
Nearly one-third of patients with epilepsy continue to have seizures despite optimal medication management. Systems employed to detect seizures may have the potential to improve outcomes in these patients by allowing more tailored therapies and might, additionally, have a role in accident and SUDEP prevention. Automated seizure detection and prediction ...
Yoon Ji Won JW Cyber Defense Department and Graduate School of Information Security, Korea University, South Korea. Electronic address: - - 2014
Projection reconstruction nuclear magnetic resonance (PR-NMR) is a technique for generating multidimensional NMR spectra. A small number of projections from lower-dimensional NMR spectra are used to reconstruct the multidimensional NMR spectra. In our previous work [1,2], it was shown that multidimensional NMR spectra are efficiently reconstructed using peak-by-peak based reversible ...
Zheng Liying L Department of Orthopedic Surgery, University of Pittsburgh, - - 2014
This manuscript presents a new subject-specific musculoskeletal dynamic modeling approach that integrates high-accuracy dynamic stereo-radiography (DSX) joint kinematics and surface-based full-body motion data. We illustrate this approach by building a model in OpenSim for a patient who participated in a meniscus transplantation efficacy study, incorporating DSX data of the tibiofemoral ...
Bowler Meghan A MA Department of Biomedical Engineering, Vanderbilt University, Nashville, TN - - 2014
Calcific aortic valve disease (CAVD) affects 25% of people over 65, and the late-stage stenotic state can only be treated with total valve replacement, requiring 85,000 surgeries annually in the US alone (University of Maryland Medical Center, 2013, http://umm.edu/programs/services/heart-center-programs/cardiothoracic-surgery/valve-surgery/facts). As CAVD is an age-related disease, many of the affected patients ...
Cuenca-Bescós Gloria G Research Group Aragosaurus-IUCA, Paleontology, Earth Sciences Department, University of Zaragoza, Zaragoza, - - 2014
The extant Cabrera's vole, Microtus cabrerae, differs in morphology and evolutionary history from the other species of Microtus. This arvicoline has unique derived features in the cranium, mandible and dentition. Probably its most conspicuous features are its large size, the high skull in lateral view, the long and distally broad ...
Brodie Jedediah F JF Departments of Zoology & Botany, Biodiversity Research Centre, University of British Columbia, 3529-6270 University Blvd, Vancouver, British Columbia, V6T 1Z4, Canada. - - 2014
Habitat corridors are important tools for maintaining connectivity in increasingly fragmented landscapes, but generally they have been considered in single-species approaches. Corridors intended to facilitate the movement of multiple species could increase persistence of entire communities, but at the likely cost of being less efficient for any given species than ...
Lee Hsiang-Ming HM 1 Department of Business and Management Chien Hsin University of Science and Technology, - - 2014
Summary.-This study examined the role of enjoyment in people's decision to barter online. A survey in barter BBS/discussion forums and websites collected data from 135 participants (30 men, 105 women; 71% in the age group of 21-30 years) who barter online. To test a modification of the Expectation Confirmation Model, ...
Karpiński Adam - - 2014
The Abraham-Carr retention time prediction model was reviewed and developed in the context of the introduction of a new stationary phase variable. The new variable consists of a binary mixture dielectric constant and a stationary phase descriptor that was derived from the Snyder-Dolan column descriptors theory. In this work, data ...
Azouni Khalid G KG BDS (JU), MSc Periodontics (JUST), DGZI GBOI, DSD, Department of Oral Maxillofacial Sciences, Alfarabi College of Dentistry and Nursing , Saudi Arabia - - 2014
Treatment of periodontal disease is a complex and multidisciplinary procedure, requiring periodontal, surgical, restorative, and orthodontic treatment modalities. Several authors attempted to formulate models for periodontal treatment that orders the treatment steps in a logical and easy to remember manner. In this article, we discuss two models of periodontal treatment ...
Koohsari Mohammad Javad MJ Behavioural Epidemiology Laboratory, Baker IDI Heart and Diabetes Institute, Melbourne, Australia; McCaughey VicHealth Centre for Community Wellbeing, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia. Electronic address: - - 2014
Built environment attributes may be important determinants of physical activity. Greater street connectivity has been shown in several studies to be associated with adults' walking for transport (WFT). We examined the extent to which this association can be explained by the availability of utilitarian destinations. Adults (n=2544) participating in the ...
Park Sohyun S NEXUS Environmental Design Center, 12 Street 4, Dongsan-ro, Seocho-gu, Seoul, 137-898, Korea, - - 2014
Although ecological connectivity conservation in urban areas has recently been recognized as an important issue, less is known about its relationship to urban form and landscape pattern. This study investigates how urban morphology influences regional ecosystem pattern and landscape connectivity. Two metropolitan landscapes, Phoenix, AZ, USA, and Izmir, Turkey, were ...
Ingólfsson Helgi I HI Groningen Biomolecular Sciences and Biotechnology Institute & Zernike Institute for Advanced Materials, University of Groningen Groningen, The - - 2014
Computational modeling of biological systems is challenging because of the multitude of spatial and temporal scales involved. Replacing atomistic detail with lower resolution, coarse grained (CG), beads has opened the way to simulate large-scale biomolecular processes on time scales inaccessible to all-atom models. We provide an overview of some of ...
Charlier Philippe P Section of Medical and Forensic Anthropology, UFR of Health Sciences (UVSQ/AP-HP), 2 Avenue de la source de la Bièvre, 78180, Montigny le Bretonneux, France, - - 2014
Based on an analysis of 19 mummified Maori heads (mokomokai) referred to our forensic laboratory for anthropological analysis prior to their official repatriation from France to New Zealand, and data from the anthropological and medical literature, we propose a complete forensic procedure for the analysis of such pieces. A list ...
D'Angelo Heather H Department of Health Behavior, University of North Carolina (UNC), Gillings School of Global Public Health, CB 7440, Chapel Hill, NC 27599-7440, USA. Electronic address: - - 2014
Identifying tobacco retail outlets for U.S. FDA compliance checks or calculating tobacco outlet density is difficult in the 13 States without tobacco retail licensing or where licensing lists are unavailable for research. This study uses primary data collection to identify tobacco outlets in three counties in a non-licensing state and ...
Cohen Emily B EB Migratory Bird Center, Smithsonian Conservation Biology Institute, National Zoological Park Washington, District of - - 2014
Understanding the biology and conducting effective conservation of migratory species requires an understanding of migratory connectivity - the geographic linkages of populations between stages of the annual cycle. Unfortunately, for most species, we are lacking such information. The North American Bird Banding Laboratory (BBL) houses an extensive database of marking, ...
Succo G G Department of Otorhinolaryngology, Ospedale San Luigi-Martini, University of Turin, Turin, - - 2014
We present herein the proposal of the European Laryngological Society working committee on nomenclature for a systematic classification of open partial horizontal laryngectomies (OPHL). This is based on the cranio-caudal extent of laryngeal structures resected, instead of a number of different and heterogeneous variables present in existing nomenclatures, usually referring ...
Rushing Clark S - - 2014
Patterns of migratory connectivity are a vital yet poorly understood component of the ecology and evolution of migratory birds. Our ability to accurately characterize patterns of migratory connectivity is often limited by the spatial resolution of the data, but recent advances in probabilistic assignment approaches have begun pairing stable isotopes ...
Beatty Adam S - - 2014
Range restriction is a common problem in personnel selection and other contexts in applied psychology. For many years researchers have used corrections that assume range restriction was direct, even when it was known that range restriction was indirect. Hunter, Schmidt, and Le (2006) proposed a new correction for cases of ...
Turan Suslu Hikmet H Department of Neurosurgery, Dr. Lutfi Kırdar Kartal Education and Research Hospital , Istanbul , - - 2014
Background. The jugular tubercle (JT) is an important part of the craniovertebral junction. The removal of the JT in the far-lateral approach provides a significant increase in the operative space. The purpose of this morphometrical study was to define the anatomical variations of the JT. Methods. Thirty-eight dry skulls were ...
- - 2014
[This corrects the article on p. 493 in vol. 17, PMID: 23922595.].
Miller Michael I MI Center for Imaging Science and Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD 21218, USA ; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, - - 2014
The Computational Anatomy project has largely been a study of large deformations within a Riemannian framework as an efficient point of view for generating metrics between anatomical configurations. This approach turns D'Arcy Thompson's comparative morphology of human biological shape and form into a metrizable space. Since the metric is constructed ...
Miller Peter - - 2014
Could I add some background information to Jennifer Trueland's 'Understanding CHARGE' article (Features January 22).
Bosch Luis Ángel Bermúdez LA Pharmaceutical Sciences Department, Medical Sciences Campus, University of Puerto Rico, - - 2014
Warfarin is the current standard of care in oral anticoagulation therapy. It is commonly prescribed to treat venous thromboembolism, pulmonary embolism, acute myocardial infarction, and to decrease the risk of stroke in atrial fibrillation. Warfarin therapy is challenging because of marked and often unpredictable inter-individual dosing variations that effectively reach ...
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