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Results 351 - 400 of 2924
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Galinha Claudia F - - 2012
In the present study, the performance of a membrane bioreactor (MBR) was modelled using a hybrid approach based on the activated sludge model number 3 (ASM3) combined with projection to latent structures (PLS) to predict the residuals of the ASM. The application of ASM to MBRs requires frequent re-calibration to ...
Deng Yu - - 2012
As a novel digital video steganography, the motion vector (MV)-based steganographic algorithm leverages the MVs as the information carriers to hide the secret messages. The existing steganalyzers based on the statistical characteristics of the spatial/frequency coefficients of the video frames cannot attack the MV-based steganography. In order to detect the ...
Gereben Orsolya - - 2012
An approach has been devised and tested for preserving the molecular dynamics molecular geometry taking into account energetic considerations during Reverse Monte Carlo (RMC) modeling. Instead of the commonly used fixed neighbor constraints, where molecules are held together by constraining distance ranges available for the specified atom pairs, here molecules ...
Cavero E - - 2012
This paper presents a methodology to transmit clinical video over wireless networks in real-time. A 3D SPIHT compression prior to transmission is proposed. In order to guarantee the clinical quality of the compressed video, a clinical evaluation specific to each video modality has to be made. This evaluation indicates the ...
Cutshall Neil S - - 2012
A series of 2-methoxyacylhydrazones were optimized to yield compounds with high affinity for PDE10A. Several compounds demonstrated efficacy in animal models of schizophrenia, including conditioned avoidance response and a pro-psychotic phencyclidine hyperactivity model.
Thill Antoine - - 2012
Through the heterogeneous nucleation of polymer nodules on a surface-modified silica particle, the high-yield achievement of hybrid colloidal molecules with a well-controlled multipod-like morphology was recently demonstrated. However, as the formation mechanism of these colloidal molecules has not been completely understood yet, some opportunities remain to reduce the tedious empirical ...
Ward S - - 2012
Rainwater harvesting is increasingly becoming an integral part of the sustainable water management toolkit. Despite a plethora of studies modelling the feasibility of the utilisation of rainwater harvesting (RWH) systems in particular contexts, there remains a significant gap in knowledge in relation to detailed empirical assessments of performance. Domestic systems ...
Varzinskas Visvaldas - - 2012
In Europe post-consumer beverage carton packages are treated in three ways: dumped in a landfill, incinerated for energy recovery, and recycled. In recent years new technologies for beverage carton recycling have been developed and tested. At the same time in Europe the collection of second-hand raw materials is becoming more ...
Liu Dezhao - - 2012
Biofiltration is a cost-effective technology for removing air contaminants from animal facilities. Kinetic analysis can aid in understanding and designing the process, but has not been performed on full-scale filters treating complex mixtures. In this study, kinetics was investigated in a full-scale biological filter treating air pollutants from a pig ...
Brown R G - - 2012
Understanding the persistence and growth of natural populations in environments subject to random localised change is relevant both to the conservation of threatened species and to the control of invasive species. By developing and analysing simple strategic growth models in environments subject to random fragmentation events, we show that simple ...
Neugebauer M - - 2012
PURPOSE: Computer-aided research on cerebral aneurysms often depends on a polygonal mesh representation of the vessel lumen. To support a differentiated, anatomy-aware analysis, it is necessary to derive anatomic descriptors from the surface model. We present an approach on automatic decomposition of the adjacent vessels into near- and far-vessel regions ...
Jia Chun-Sheng - - 2012
By employing the dissociation energy and the equilibrium bond length for a diatomic molecule as explicit parameters, we generate improved expressions for the well-known Rosen-Morse, Manning-Rosen, Tietz, and Frost-Musulin potential energy functions. It is found that the well-known Tietz potential function that is conventionally defined in terms of five parameters ...
Heiber Michael C - - 2012
A general dynamic Monte Carlo model for exciton dissociation at a donor-acceptor interface that includes exciton delocalization and hot charge separation is developed to model the experimental behavior observed for the poly(3-hexylthiophene):fullerene system and predict the theoretical performance of future materials systems. The presence of delocalized excitons and the direct ...
Brondfield Max N - - 2012
On-road emissions are a major contributor to rising concentrations of atmospheric greenhouse gases. In this study, we applied a downscaling methodology based on commonly available spatial parameters to model on-road CO(2) emissions at the 1 × 1 km scale for the Boston, MA region and tested our approach with surface-level CO(2) observations. Using ...
Whitehead Kathryn A - - 2012
A significant challenge in the development of clinically viable siRNA delivery systems is a lack of in vitro-in vivo translatability: many delivery vehicles that are initially promising in cell culture do not retain efficacy in animals. Despite its importance, little information exists on the predictive nature of in vitro methodologies, ...
Jung Sung-Hee - - 2012
The industrial Single Photon Emission Computerized Tomography (SPECT) system comprised of 30 sets of lead collimated 2in. NaI(Tl) detectors was built and utilized for measuring the spatial distribution of radiotracers as a function of time at a predefined cross-sectional level of a tank with a diameter of 300mm and a ...
Müller Stefan - - 2012
Gas-liquid mass transfer is often rate-limiting in laboratory and industrial cultures of aerobic or autotrophic organisms. The volumetric mass transfer coefficient k(L) a is a crucial characteristic for comparing, optimizing, and upscaling mass transfer efficiency of bioreactors. Reliable dynamic models and resulting methods for parameter identification are needed for quantitative ...
Wu Yerong - - 2012
Estimating particulate matter (PM) from space is not straightforward and is mainly achieved using the aerosol optical depth (AOD) retrieved from satellite sensors. However, AOD is a columnar measure, whereas PM is a ground observation. Linking AOD and PM remains a challenge for air pollution monitoring. In this study, a ...
Liu Baoquan - - 2012
We present a novel approach for GPU-based high quality volume rendering of large out-of-core volume data. By focusing on the locations and costs of ray traversal, we are able to significantly reduce the rendering time over traditional algorithms. We store a volume in an octree (of bricks); in addition, every ...
Guélat Bertrand - - 2012
A model was developed for the design of a monoclonal antibody charge variants separation process based on ion-exchange chromatography. In order to account for a broad range of operating conditions in the simulations, an explicit pH and salt concentration dependence has been included in the Langmuir adsorption isotherm. The reliability ...
McGinitie Teague M - - 2012
Thermodynamic modeling of retention times in gas chromatography depends on the accurate estimation of thermodynamic parameters. Previous research has used manual injections of samples with coinjection of a dead time marker to obtain accurate measurements of the retention factor of analytes. Ideally this process would be automated. Herein an approach ...
Raval Jay S JS The Institute for Transfusion Medicine, Pittsburgh, PA, USA. - - 2012
Airborne particulate monitoring is mandated as a component of good manufacturing practice. We present a procedure developed to monitor and interpret airborne particulates in an International Organization for Standardization (ISO) class 7 cleanroom used for the cell processing of Section 351 and Section 361 products. We collected paired viable and ...
Bishop Martin J MJ Department of Biomedical Engineering, Division of Imaging Sciences King’s College London, London, UK. - - 2012
Fine-scale anatomical structures in the heart may play an important role in sustaining cardiac arrhythmias. However, the extent of this role and how it may differ between species are not fully understood. In this study we used computational modelling to assess the impact of anatomy upon arrhythmia maintenance in the ...
Jermakian Jessica S - - 2012
OBJECTIVES: The objective of this paper was to estimate the maximum potential large truck crash reductions in the United States associated with each of four crash avoidance technologies: side view assist, forward collision warning/mitigation, lane departure warning/prevention, and vehicle stability control. Estimates accounted for limitations of current systems. METHODS: Crash ...
Hoy Matthew B - - 2012
This article explores the basic principles of web-scale discovery systems and how they are being implemented in libraries. "Web scale discovery" refers to a class of products that index a vast number of resources in a wide variety formats and allow users to search for content in the physical collection, ...
Quo Chang F - - 2012
Recent advances in high-throughput biotechnologies have led to the rapid growing research interest in reverse engineering of biomolecular systems (REBMS). 'Data-driven' approaches, i.e. data mining, can be used to extract patterns from large volumes of biochemical data at molecular-level resolution while 'design-driven' approaches, i.e. systems modeling, can be used to ...
Chmielewski R - - 2012
The objective of this work was to create a comprehensive online tool to evaluate and review the performance of quality assurance measurements that assess beam output and profile constancy as soon as they are acquired using statistical process control. As part of routine quality assurance: output, flatness and symmetry measurements ...
Angers C - - 2012
The aim of this work was to apply failure modes and effect analysis (FMEA) to assess risk in two radiation planning and treatment processes; our on-call (out-of-clinical hours) process and our tomotherapy process. The motivation was provided by analysis of 2506 adverse incidents reported over a 5 year period, the ...
Hall Connie L - - 2012
Implantation of vascular grafts or stents causes significant injury to the vessel wall. Activated coagulation factors, such as FXa are generated at the injury site. The size of the injury and the flow conditions influence the transport of these activated factors. A simulation model has been developed to evaluate surface ...
Hadley Kevin R - - 2012
Coarse-grained (CG) models have proven to be very effective tools in the study of phenomena or systems that involve large time- and length-scales. By decreasing the degrees of freedom in the system and using softer interactions than seen in atomistic models, larger timesteps can be used and much longer simulation ...
Chen A A Rutgers University, Department of Biomedical Engineering, 599 Taylor Road, Piscataway, NJ 08854, - - 2012
There is a large emphasis within the pharmaceutical industry to provide tools that will allow early research and development groups to better predict dose ranges for and metabolic responses of candidate molecules in a high throughput manner, prior to entering clinical trials. These tools incorporate approaches ranging from PBPK, QSAR, ...
Trueman C N - - 2012
The isotopic composition of many elements varies across both land and ocean surfaces in a predictable fashion. These stable-isotope ratios are transferred into animal tissues, potentially providing a powerful natural geospatial tag. To date, most studies using stable isotopes as geolocators in marine settings have focussed on mammals and seabirds ...
Boyden Suzanne - - 2012
Forest ecosystem processes depend on local interactions that are modified by the spatial pattern of trees and resources. Effects of resource supplies on processes such as regeneration are increasingly well understood, yet we have few tools to compare resource heterogeneity among forests that differ in structural complexity. We used a ...
Finlayson Graham D - - 2012
There are many works in color that assume illumination change can be modeled by multiplying sensor responses by individual scaling factors. The early research in this area is sometimes grouped under the heading "von Kries adaptation": the scaling factors are applied to the cone responses. In more recent studies, both ...
Han Sehyun - - 2012
This study is considered the first attempt to apply a mobile monitoring system to estimating silt loading on paved roads in a megacity such as the Seoul metropolitan area. Using a mobile monitoring system developed in 2005, we estimated silt loadings on representative paved roads in the Seoul metropolitan area, ...
Garner J P - - 2012
Hen performance can be affected by many interacting variables related to cage design, such as floor area, height, tier arrangement, and feeder and drinker type and placement within the cage. Likewise, features of house design such as waste management and lighting can also affect hen productivity. The influence of these ...
Gharibzahedi Seyed Mohammad Taghi - - 2012
An acceptable strategy to incorporate canthaxanthin (CX) as a natural colorant into products is by means of oil-in-water emulsions. The used CX in this study was produced by bacterium Dietzia natronolimnaea HS-1 using a batch bioreactor system. A central composite rotatable design-response surface methodology (CCRD-RSM) consisting of three-factored factorial design ...
Ben Hariz Maher - - 2012
In this paper, we present the synthesis of a robust controller for Linear Time Invariant (LTI) uncertain systems. A linear parametric uncertainties model is used to describe the system dynamic behavior. The main purpose of this controller is to guarantee some step response performances such as the settling time and ...
Whelan Jessica - - 2012
In this study, the application of Raman spectroscopy to the simultaneous quantitative determination of glucose, glutamine, lactate, ammonia, glutamate, total cell density and viable cell density in a CHO fed-batch process was demonstrated in situ in 3 L and 15 L bioreactors. Spectral pre-processing and partial least squares (PLS) regression ...
Yu Zhengdao - - 2012
The severity factor is a common term used in steam explosion (SE) pretreatment that describes the combined effects of the temperature and duration of the pretreatment. However, it ignores the duration of the explosion process. This paper describes a new parameter, the explosion power density (EPD), which is independent of ...
Lin Yen-Hui - - 2012
A non-steady-state mathematical model system for the kinetics of adsorption and biodegradation of reactive black 5 (RB5) by Funalia trogii (F. trogii) ATCC 200800 biofilm on fly ash-chitosan bead in the fluidized bed process was derived. The mechanisms in the model system included adsorption by fly ash-chitosan beads, biodegradation by ...
Hsu C T - - 2012
Crumpled sheets of paper tend to exhibit specific and complex structure, which is described as ridge networks by physicists. Existing literature showed that automation of ridge network detection in crumpled paper is very challenging because of its complex structure and the measuring distortion. In this paper, we propose to model ...
Li Fangfei - - 2012
This paper investigates the controllability and optimal control of a temporal Boolean network, where the time delays are time variant. First, using the theory of semi-tensor product of matrices, the logical systems can be converted into a discrete time variant system. Second, necessary and sufficient conditions for the controllability via ...
Oehler Dorothy Z - - 2012
Abstract This paper presents the hypothesis that the well-known giant polygons and bright mounds of the martian lowlands may be related to a common process-a process of fluid expulsion that results from burial of fine-grained sediments beneath a body of water. Specifically, we hypothesize that giant polygons and mounds in ...
Storch David - - 2012
Despite the broad conceptual and applied relevance of how the number of species or endemics changes with area (the species-area and endemics-area relationships (SAR and EAR)), our understanding of universality and pervasiveness of these patterns across taxa and regions has remained limited. The SAR has traditionally been approximated by a ...
Fekete Szabolcs - - 2012
Monoclonal antibodies (mAbs) are an emerging class of therapeutic agents that have recently gained importance. To attain acceptable kinetic performance with mAbs in reversed phase liquid chromatography, there is a need to work with the last generation of wide-pore sub-2μm fully porous or core-shell particles stationary phases. In addition, temperature ...
Ebrahim Sahraeian Sayed Mohammad - - 2012
MOTIVATION: Recent technological advances in measuring molecular interactions have resulted in an increasing number of large-scale biological networks. Translation of these enormous network data into meaningful biological insights requires efficient computational techniques that can unearth the biological information that is encoded in the networks. One such example is network querying, ...
Lee Ki-Don - - 2012
An optimization analysis of a ski jumper's posture has been performed to improve the lift-to-drag ratio, and to examine aerodynamic stability to ensure flight control and safety. Three-dimensional Reynolds-averaged Navier-Stokes equations were discretized using finite volume approximations for the flow analysis, and the shear stress transport k-ω turbulence model was ...
Peng Fei - - 2012
We study the treatment plan optimization problem for volumetric modulated arc therapy (VMAT). We propose a new column-generation-based algorithm that takes into account bounds on the gantry speed and dose rate, as well as an upper bound on the rate of change of the gantry speed, in addition to MLC ...
Limaye Bhakti B Bioinformatics Group, Centre for Development of Advanced Computing, Pune University Campus, Ganesh Khind, Pune - 411007, Maharashtra, - - 2012
Anvaya is a workflow environment for automated genome analysis that provides an interface for several bioinformatics tools and databases, loosely coupled together in a coordinated system, enabling the execution of a set of analyses tools in series or in parallel. It is a client-server workflow environment that has an advantage ...
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