Search Results
Results 1 - 50 of 2022
1 2 3 4 5 6 7 8 9 10 >
Mirzaei Majid M Department of Mechanical Engineering, Tarbiat Modares University, Tehran, Iran P.O. Box: 14115-143. Electronic address: - - 2014
This paper presents a novel method for fast and reliable prediction of the failure strength of human proximal femur, using the quantitative computed tomography (QCT)-based linear finite element analysis (FEA). Ten fresh frozen human femora (age: 34±16) were QCT-scanned and the pertinent 3D voxel-based finite element models were constructed. A ...
Janssens Pim Mw PM Laboratory of Clinical Chemistry and Haematology, Rijnstate Hospital, The - - 2014
Prospective risk analysis (PRA) is an essential element in quality assurance for clinical laboratories. Practical approaches to conducting PRA in laboratories, however, are scarce. On the basis of the classical Failure Mode and Effect Analysis method, an approach to PRA was developed for application to key laboratory processes. First, the ...
Campbell Alan O AO Department of Psychology, Clemson University, Clemson, SC 29634, USA; Applied Building Sciences Inc., Charleston, SC 29405, USA. Electronic address: - - 2014
Accidents involving portable ladders are a common cause of serious occupational and non-occupational injuries throughout the industrialized world. Many of these injuries could be prevented with better instruction on the proper usage of portable ladders. Research is reported that focused on both the human factors and engineering aspects of portable ...
Trajkovski Ana - - 2014
Cervical spine ligaments have an important role in providing spinal cord stability and restricting excessive movements. Therefore, it is of great importance to study mechanical properties and model the response of these ligaments. The aim of this study is to characterize ageing effects on failure properties and model damage of ...
Shah Sachin - - 2014
Ascending thoracic aortic aneurysms (ATAA) have a high propensity for dissection, which occurs when the hemodynamic load exceeds the mechanical strength of the aortic media. Despite our recognition of this essential fact, the complex architecture of the media has made a predictive model of medial failure - even in the ...
Khan S U SU School of Engineering & Applied Sciences, ISRA University, Islamabad 44000, - - 2014
Three issues regarding sensor failure at any position in the antenna array are discussed. We assume that sensor position is known. The issues include raise in sidelobe levels, displacement of nulls from their original positions, and diminishing of null depth. The required null depth is achieved by making the weight ...
Ning Jing J Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, - - 2013
This article targets the estimation of a time-dependent association measure for bivariate failure times, the conditional cause-specific hazards ratio (CCSHR), which is a generalization of the conditional hazards ratio (CHR) to accommodate competing risks data. We model the CCSHR as a parametric regression function of time and event causes and ...
Han Seung-Ryong - - 2013
Utility systems such as power and communication systems regularly experience significant damage and loss of service during hurricanes. A primary damage mode for these systems is failure of wooden utility poles that support conductors and communication lines. In this article, we present an approach for combining structural reliability models for ...
Armon Bruce D - - 2013
The September 23, 2013, deadline for covered entities, business associates, and their subcontractors to comply with new HIPAA rules is fast approaching. Now is the time to ensure HIPAA compliance before the deadline arrives and avoid any penalties that could result from failure to act.
Guidi G - - 2013
In this study, we describe an automatic classifier of patients with Heart Failure designed for a telemonitoring scenario, improving the results obtained in our previous works. Our previous studies showed that the technique that better processes the heart failure typical telemonitoring-parameters is the Classification Tree. We therefore decided to analyze ...
James William H - - 2013
The Trivers-Willard (TW) argument may be interpreted to yield a large class of true predictions, and a small class of false predictions. This would explain the relative numbers of empirical successes and failures of TW. It is argued here that in mammals (including man), one cause of these failures is ...
Titman Andrew C - - 2013
A likelihood based approach to obtaining non-parametric estimates of the failure time distribution is developed for the copula based model of Wang et al. (Lifetime Data Anal 18:434-445, 2012) for current status data under dependent observation. Maximization of the likelihood involves a generalized pool-adjacent violators algorithm. The estimator coincides with ...
Untaroiu Costin D - - 2013
The liver is one of the most frequently injured abdominal organs during motor vehicle crashes. Realistic car crash simulations require incorporating strain-rate dependent mechanical properties of soft tissue in finite element (FE) material models. This study presents a total of 30 tension tests performed on fresh bovine liver parenchyma at ...
Hu Tianle - - 2013
The cross-ratio is an important local measure that characterizes the dependence between bivariate failure times. To estimate the cross-ratio in follow-up studies where delayed entry is present, estimation procedures need to account for left truncation. Ignoring left truncation yields biased estimates of the cross-ratio. We extend the method of Hu ...
Baydemir Canan - - 2013
OBJECTIVE: The specific purpose of this study was to investigate the validity of the Turkish version of the European Heart Failure Self-care Behavior Scale by applying to 494 Turkish Heart Failure Patients. METHODS: The study was conducted as a cross-sectional sample survey, between October 2012 and January 2013. The 494 ...
Scheidegger Andreas - - 2013
Predictions of the expected number of failures of water distribution network pipes are important to develop an optimal management strategy. A number of probabilistic pipe failure models have been proposed in the literature for this purpose. They have to be calibrated on failure records. However, common data management practices mean ...
Schneider Christian M - - 2013
Interconnected networks have been shown to be much more vulnerable to random and targeted failures than isolated ones, raising several interesting questions regarding the identification and mitigation of their risk. The paradigm to address these questions is the percolation model, where the resilience of the system is quantified by the ...
Mayordomo-Colunga Juan - - 2013
PURPOSE: Our objective was to assess whether SpO2/FiO2 (SF) ratio could be a useful NIV outcome predictor in children with acute respiratory failure (ARF) and tried to develop a predictive model of NIV failure. METHODS: Prospective, observational, multicenter study. Episodes of ARF-fulfilling inclusion criteria from 15 January 2010 to 14 ...
Nishiyama Kyle K - - 2013
Finite element (FE) analysis based on quantitative computed tomography (QCT) images is an emerging tool to estimate bone strength in a specific patient or specimen; however, it is limited by the computational power required and the associated time required to generate and solve the models. Thus, our objective was to ...
Lee Anna - - 2013
OBJECTIVE:: To facilitate the planning of perioperative care pathways, a fast-track failure prediction model has been developed in patients undergoing cardiac surgery. This study externally validated such a fast-track failure risk prediction model and determined the potential clinical consequences to ICU bed utilization. DESIGN:: Prospective cohort study. SETTING:: Cardiothoracic Surgery ...
Shang C - - 2013
A numerical method to predict the break force of curved faced tablets is proposed. The constitutive model and the failure criteria necessary to obtain predictions consistent with experimental data are identified. A modified Drucker-Prager cap model together with a maximum principal stress based failure criteria were found sufficient to predict ...
Caballero Morales Santiago Omar - - 2013
The application of Preventive Maintenance (PM) and Statistical Process Control (SPC) are important practices to achieve high product quality, small frequency of failures, and cost reduction in a production process. However there are some points that have not been explored in depth about its joint application. First, most SPC is ...
Huang Xuqing - - 2013
As economic entities become increasingly interconnected, a shock in a financial network can provoke significant cascading failures throughout the system. To study the systemic risk of financial systems, we create a bi-partite banking network model composed of banks and bank assets and propose a cascading failure model to describe the ...
Alwan Faris M - - 2013
The reliability of the electrical distribution system is a contemporary research field due to diverse applications of electricity in everyday life and diverse industries. However a few research papers exist in literature. This paper proposes a methodology for assessing the reliability of 33/11 Kilovolt high-power stations based on average time ...
Bryant Robby J - - 2013
Single points of failure may spell disaster for businesses that have not adequately identified and mitigated these critical risks. A single point of failure audit will identify the single points of failure in all functional areas that may negatively impact organisational processes and process flows. This paper provides a holistic ...
Flanagan Owen - - 2013
Addiction is a person-level phenomenon that involves twin normative failures. A failure of normal rational effective agency or self-control with respect to the substance; and shame at both this failure, and the failure to live up to the standards for a good life that the addict himself acknowledges and aspires ...
Wang Wei-Ming WM College of Civil Engineering of Shandong University of Science and Technology, Qingdao, Shandong 266590, - - 2013
Mining areas in western China are mainly located in soft rock strata with poor bearing capacity. In order to make the deformation failure mechanism and strength behavior of weakly consolidated soft mudstone and coal rock hosted in Ili No. 4 mine of Xinjiang area clear, some uniaxial and triaxial compression ...
Gervais Brian - - 2012
Abstract Pharmaceutical quality systems use various inputs to ensure product quality and prevent failures that might have patient consequences. These inputs are generally data from failures that have already occurred, for example process deviations or customer complaints. Risk analysis techniques are well-established in certain other industries and have become of ...
Zhou Di - - 2012
It was recently recognized that interdependencies among different networks can play a crucial role in triggering cascading failures and, hence, systemwide disasters. A recent model shows how pairs of interdependent networks can exhibit an abrupt percolation transition as failures accumulate. We report on the effects of topology on failure propagation ...
Ong Mei-Sing MS Centre for Health Informatics, University of New South Wales, Sydney, Australia. - - 2013
To explore the applicability of a syndromic surveillance method to the early detection of health information technology (HIT) system failures. A syndromic surveillance system was developed to monitor a laboratory information system at a tertiary hospital. Four indices were monitored: (1) total laboratory records being created; (2) total records with ...
Molnar David - - 2012
Background: This study examined the success of an admission screen in identifying applicants who will fail Part I or Part II of the Podiatric Boards on the first attempt. Methods: A logistic regression model was used to predict failure on the Podiatric Boards. Results: The biology Medical College Admission Test ...
Johnson Timothy P - - 2012
This paper reviews some of the potential sources of failure in surveys concerned with substance use. These failures are both conceptual and methodological in nature. Conceptual failures include nonuse and misuse of survey data, the inability of these data to detect emerging substance use trends and problems, and relevant ethical ...
Arbaugh Melissa - - 2012
OBJECTIVE: To compare the load to failure of incisional gastropexy performed with standard glycomer 631 (G) and with knotless glycomer 631 (GV) in ex vivo model of gastropexy. STUDY DESIGN: Cadaveric study. SAMPLE POPULATION: Cadaveric canine stomach and body wall (n = 24). METHODS: Specimens were divided into 4 groups ...
Taylor David D Mechanical Engineering Department, Trinity Centre for Bioengineering, Trinity College Dublin, Dublin 2, Ireland. - - 2012
This paper addresses the question of strength and mechanical failure in exoskeletons and endoskeletons. We developed a new, more sophisticated model to predict failure in bones and other limb segments, modelled as hollow tubes of radius r and thickness t. Five failure modes were considered: transverse fracture; buckling (of three ...
Hadi Mohammad F - - 2012
Excessive tissue-level forces communicated to the microstructure and extracellular matrix of soft tissues can lead to damage and failure through poorly understood physical processes that are multiscale in nature. In this work, we propose a multiscale mechanical model for the failure of collagenous soft tissues that incorporates spatial heterogeneity in ...
Manepalli Sankar - - 2012
With the breakthrough crystallization of the bacterial leucine transporter protein LeuT, the first available X-ray structure for the neurotransmitter/sodium symporter family, development of 3-D computational models is suddenly essential for structure-function studies on the plasmalemmal monoamine transporters (MATs). LeuT-based MAT models have been used to guide elucidation of substrate and ...
Wang Lei - - 2012
Understanding the transport mechanism of 1,3-propanediol (1,3-PD) is of critical importance to do further research on gene regulation. Due to the lack of intracellular information, on the basis of enzyme-catalytic system, using biological robustness as performance index, we present a system identification model to infer the most possible transport mechanism ...
Hülsmann Bastian B - - 2012
Nuclear pore complexes (NPCs) maintain a permeability barrier between the nucleus and the cytoplasm through FG-repeat-containing nucleoporins (Nups). We previously proposed a "selective phase model" in which the FG repeats interact with one another to form a sieve-like barrier that can be locally disrupted by the binding of nuclear transport receptors ...
Fransson Martin N - - 2012
PURPOSE: To build a semi-physiologically based pharmacokinetic model describing the uptake, metabolism and efflux of paclitaxel and its metabolites and investigate the effect of hypothetical genetic polymorphisms causing reduced uptake, metabolism or efflux in the pathway by model simulation and sensitivity analysis. METHODS: A previously described intracellular pharmacokinetic model was ...
Berry Alan - - 2012
This paper describes details of an oil spill model, OILTRANS, developed by the authors. The model is an off-line particle-transport model coupled to the most up to date operational met-ocean model forecasts. Formulations for the dominant oil fate processes of spreading, advection, diffusion, evaporation, emulsification and dispersion have been encoded, ...
Psachoulias Dimitrios - - 2012
PURPOSE: To develop an in vitro methodology for prediction of concentrations and potential precipitation of highly permeable, lipophilic weak bases in fasted upper small intestine based on ketoconazole and dipyridamole luminal data. Evaluate usefulness of methodology in predicting luminal precipitation of AZD0865 and SB705498 based on plasma data. METHODS: A ...
Zimanyi Eric N - - 2012
Recent experiments on light-harvesting complexes have shown clear indication of coherent transport of excitations in these aggregates. We discuss the theoretical models that have been used to study energy transfer in molecular aggregates, beginning with the early models of Förster and Davydov and ending with the theoretical models of the ...
Oldfield Matthew - - 2012
The advantageous, curved trajectory of beveltipped devices in soft tissue is a function of the interplay between material deformation, contact interactions and material failure. Highly detailed modeling of tool-tissue interactions is therefore vital in optimising performance and design. At high resolution, discontinuous failure of soft tissue phantoms has not been ...
Ball Kathryn - - 2012
A whole-body physiologically based pharmacokinetic (PBPK) model was developed for the prediction of unbound drug concentration-time profiles in the rat brain, in which drug transfer across the blood-brain barrier (BBB) was treated mechanistically by separating the parameters governing the rate (permeability) of BBB transfer from brain binding. An in vitro-in ...
Zhang Xianming - - 2012
Air sampling based on diffusion of target molecules from the atmospheric gas phase to passive sampling media (PSMs) is currently modeled using the two-film approach. Originally developed to describe chemical exchange between air and water, it assumes a uniform chemical distribution in the bulk phases on either side of the ...
Frank K L - - 2012
The gypsy moth, Lymantria dispar, is a non-native species that continues to invade areas in North America. It spreads generally through stratified dispersal where local growth and diffusive spread are coupled with long-distance jumps ahead of the leading edge. Long-distance jumps due to anthropogenic movement of life stages is a ...
Morway Eric D - - 2012
The MT3DMS groundwater solute transport model was modified to simulate solute transport in the unsaturated zone by incorporating the unsaturated-zone flow (UZF1) package developed for MODFLOW. The modified MT3DMS code uses a volume-averaged approach in which Lagrangian-based UZF1 fluid fluxes and storage changes are mapped onto a fixed grid. Referred ...
Motaghinasab S - - 2012
A finite element model is developed to predict the penetration time-history of three different solutes into the human lumbar disc following intravenous injection. Antibiotics are routinely administered intravenously in spinal surgery to prevent disc infection. Successful prophylaxis requires antibiotics to reach adequate inhibitory levels. Here, the transient diffusion of cephazolin ...
Beekhuizen Johan - - 2012
Integration of individual time-location patterns with spatially resolved exposure maps enables a more accurate estimation of personal exposures to environmental pollutants than using estimates at fixed locations. Current global positioning system (GPS) devices can be used to track an individual's location. However, information on GPS-performance in environmental exposure assessment is ...
Hillebrand Olav - - 2012
Little is known with respect to the attenuation capacity of karst aquifers. Even less is known about the risk posed by emerging micropollutants in these systems. In order to identify the attenuation potential of karst aquifers in-situ and to estimate the risk posed by micropollutants, a dualtracer test was conducted ...
1 2 3 4 5 6 7 8 9 10 >