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Attia Mohammed Sabri MS Division of Neurosurgery, St. Michael's Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, - - 2015
Subarachnoid hemorrhage (SAH) remains one of the most morbid subtypes of stroke around the world and has been the focus of hemorrhagic stroke research for longer than five decades. Animal models have been instrumental in shaping the progress and advancement of SAH research, particularly models that allow for transgenic manipulation. ...
Cai Yongli Y Department of Mathematics, Sun Yat-Sen University, Guangzhou 510275, China. - - 2014
In this article, we study the rich dynamics of a diffusive predator-prey system with Allee effects in the prey growth. Our model assumes a prey-dependent Holling type-II functional response and a density dependent death rate for predator. We investigate the dissipation and persistence property, the stability of nonnegative and positive ...
Luna Jose Maria - - 2014
This paper proposes a novel grammar-guided genetic programming algorithm for subgroup discovery. This algorithm, called comprehensible grammar-based algorithm for subgroup discovery (CGBA-SD), combines the requirements of discovering comprehensible rules with the ability to mine expressive and flexible solutions owing to the use of a context-free grammar. Each rule is represented ...
Grewal Navneet N Department of Pedodontics and Preventive Dentistry, Punjab Government Dental College and Hospital, Amritsar, Punjab, - - 2014
Prevention of orofacial injuries is one of the biggest pre-occupations in sports dentistry. The custom-fitted mouthguard is considered the best choice for fit and protection when compared to over-the-counter commercial mouthguards. However, cost and time prohibit their mass production. It is therefore imperative to have an over-the-counter true mouth-formed mouthguard ...
Kalra Mayank M Laboratory for Alternative Energy Conversion (LAEC), School of Mechatronic Systems Engineering, Simon Fraser University, 250-13450 102nd Avenue, Surrey, BC, V3T 0A3, Canada, - - 2014
Therapeutic hypothermia is rapidly becoming an integral part of post-resuscitative care for post-cardiac arrest and neurotrauma patients. Despite the significant impact of thermoregulation on core temperature drop during rapid cooling, current mathematical models for thermoregulation have not been validated for hypothermic conditions. A geometrically accurate 3D model of an upper ...
Teschke Kay - - 2014
Widely varying crash circumstances have been reported for bicycling injuries, likely because of differing bicycling populations and environments. We used data from the Bicyclists' Injuries and the Cycling Environment Study in Vancouver and Toronto, Canada, to describe the crash circumstances of people injured while cycling for utilitarian and leisure purposes. ...
Cosic Nela - - 2014
Although abbreviated surgery with planned reoperation (damage control surgery) is now widely used to manage major trauma patients, the procedure and its component interventions have not been evaluated in randomized controlled trials (RCTs). While some have suggested the need for such trials, they are unlikely to be conducted because of ...
Veliz-Cuba Alan A Department of Mathematics, University of Houston, Houston, TX, 77204-3008, USA, - - 2014
Models of biochemical networks are frequently complex and high-dimensional. Reduction methods that preserve important dynamical properties are therefore essential for their study. Interactions in biochemical networks are frequently modeled using Hill functions ([Formula: see text]). Reduced ODEs and Boolean approximations of such model networks have been studied extensively when the ...
Crisco Joseph J JJ Bioengineering Laboratory, Department of Orthopaedics, Warren Alpert Medical School of Brown University, and Rhode Island Hospital, Providence, - - 2014
Girls' lacrosse is fundamentally a different sport than boys' lacrosse, and girls are not required to wear protective headgear. Recent epidemiological studies have found that stick checks are the leading cause of concussion injury in girls' lacrosse. The purpose of this study was to determine stick check speeds and estimate ...
Toya Yoshihiro Y Department of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, 1-5 Yamadaoka, Suita, Osaka, 565-0871, Japan; Advanced Low Carbon Technology Research and Development Program, Japan Science and Technology Agency (JST, - - 2014
Metabolic pathway modification based on the stoichiometric model has been an effective approach for enhancing microbial bio-production. The network of optimal pathways for "growth-associated" and "non-growth-associated" production can be designed from the flux variability (solution space). The present study introduces a new computational method (solution space design [SSDesign]) that visually ...
Zanith Caroline C CC Departamento de Ciências Naturais, Universidade Federal de São João del-Rei, São João del-Rei, MG, 36301-160, - - 2014
The continuum solvation models SMD and SM8 were developed using 2,346 solvation free energy values for 318 neutral molecules in 91 solvents as reference. However, no solvation data of neutral solutes in methanol was used in the parametrization, while only few solvation free energy values of solutes in dimethyl sulfoxide ...
Romps David M DM Department of Earth and Planetary Science, University of California, Berkeley, and Earth Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. - - 2014
Lightning plays an important role in atmospheric chemistry and in the initiation of wildfires, but the impact of global warming on lightning rates is poorly constrained. Here we propose that the lightning flash rate is proportional to the convective available potential energy (CAPE) times the precipitation rate. Using observations, the ...
Gawthrop Peter J PJ Systems Biology Laboratory , Melbourne School of Engineering, University of Melbourne , Victoria 3010, - - 2014
Thermodynamic aspects of chemical reactions have a long history in the physical chemistry literature. In particular, biochemical cycles require a source of energy to function. However, although fundamental, the role of chemical potential and Gibb's free energy in the analysis of biochemical systems is often overlooked leading to models which ...
Sakharova L V LV Rostov State University of Economics, Department of Fundamental and Applied Mathematics , Rostov-on-Don, - - 2014
The mathematical model describing the stationary natural pH-gradient arising under the action of an electric field in an aqueous solution of ampholytes is constructed and investigated. The model is a part of a more general model of the isoelectrofocusing process. Investigation is based on the approximation of a weak solution ...
Held Alexander A Freiburger Materialforschungszentrum, Albert-Ludwigs-Universität Freiburg, Stefan-Meier-Straße 21, D-79104 Freiburg, - - 2014
We present a continuum solvent model (CSM) with a smooth cavity for the application in grid-based electronic structure methods. The cavity is identified with the inherently smooth distribution function of a binary mixture at infinite dilution. We obtain a cavity model based on atomic van der Waals radii and one ...
Stockdale Gregory G Department of Statistical Sciences, Projects Clinical Platform, R&D, GlaxoSmithKline, King of Prussia, Pennsylvania, - - 2014
Comparing higher order structure (HOS) in therapeutic proteins is a significant challenge. Previously, we showed that changes in solution conditions produced detectable changes in the second-derivative amide I Fourier transform infrared (FTIR) spectra for a variety of model proteins. Those comparisons utilized vector-based approaches, such as spectral overlap and spectral ...
Eid Hani O HO Department of Surgery, College of Medicine and Health Sciences, UAE University, PO Box 17666, Al Ain, - - 2014
Pedestrians are vulnerable road users who are at risk of injuries and death on the roads. We aimed to define factors affecting pedestrian injuries-related deaths worldwide and to give recommendations regarding their prevention priorities. Data on pedestrian injuries-related deaths for years 2007 and 2010 were retrieved from the WHO global ...
Stary Tomas - - 2014
The modern Markov chain models of ionic channels in excitable membranes are numerically stiff. The popular numerical methods for these models require very small time steps to ensure stability. Our objective is to formulate and test two methods addressing this issue, so that the timestep can be chosen based on ...
Wang Wei W Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, 430060, People's Republic of - - 2014
Intracerebral hemorrhagic transformation (HT) is well recognized as a common cause of hemorrhage in patients with ischemic stroke. HT after acute ischemic stroke contributes to early mortality and adversely affects functional recovery. The risk of HT is especially high when patients receive thrombolytic reperfusion therapy with tissue plasminogen activator, the ...
Wirth Roland R Institut für Kernphysik, Technische Universität Darmstadt, Schlossgartenstraße 2, 64289 Darmstadt, - - 2014
We present the first ab initio calculations for p-shell single-Λ hypernuclei. For the solution of the many-baryon problem, we develop two variants of the no-core shell model with explicit Λ and Σ^{+},Σ^{0},Σ^{-} hyperons including Λ-Σ conversion, optionally supplemented by a similarity renormalization group transformation to accelerate model-space convergence. In addition to ...
Awoukeng Goumtcha Aristide A Institut de Recherche sur les Transports, l'Energie, la Société (IRTES - M3M), Université de Technologie de Belfort-Montbéliard UTBM, Belfort, Cedex, 90010, - - 2014
Injury mechanisms due to high speed dynamic loads, such as blasts, are not well understood. These research fields are widely investigated in the literature, both at the experimental and numerical levels, and try to answer questions about the safety and efficiency of protection devices or biomechanical traumas. At a numerical ...
Wang Hao H Department of Traditional Chinese Internal Medicine, China-Japan Friendship Hospital, Beijing 100029, P.R. - - 2014
The aim of this study was to establish a mouse model of vascular dementia (VaD) in order to overcome the shortcomings of rat models of VaD, which include high production costs, difficult surgery, surgical trauma and high mortality. In this study, repeated ischemia-reperfusion of the total bilateral carotid artery in ...
Yazidi Anis - - 2014
Stochastic point location (SPL) deals with the problem of a learning mechanism (LM) determining the optimal point on the line when the only input it receives are stochastic signals about the direction in which it should move. One can differentiate the SPL from the traditional class of optimization problems by ...
Zhong Fujin - - 2014
Conventional discriminant locality preserving projection (DLPP) is a dimensionality reduction technique based on manifold learning, which has demonstrated good performance in pattern recognition. However, because its objective function is based on the distance criterion using L2-norm, conventional DLPP is not robust to outliers which are present in many applications. This ...
Greschner Sebastian S Institut für Theoretische Physik, Leibniz Universität Hannover, Appelstrasse 2, DE-30167 Hannover, - - 2014
Recent experiments show that periodic modulations of cold atoms in optical lattices may be used to engineer and explore interesting models. We show that double modulation combining lattice shaking and modulated interactions allows for the engineering of a much broader class of lattice with correlated hopping, which we study for ...
Zimmerman Karen K a Amend , PO Box 38474 Dar es Salaam , - - 2014
Abstract OBJECTIVE Road traffic injuries (RTIs) are a major public health burden, especially in low and middle-income countries. There is limited data on RTIs in low volume, rural African settings. This study attempted to survey all individuals living in households within 200 meters of two low-volume rural roads in Tanzania ...
Vagal Achala S AS From the Department of Radiology (A.S.V., T.A.T.), Department of Neurology (P.K., J.P.B.), and Department of Internal Medicine (M.H.E.), University of Cincinnati Medical Center, OH; and Department of Public Health Sciences, Medical University of South Carolina, Charleston (S.D.Y.). - - 2014
Our objective was to use decision analytic modeling to compare 2 treatment strategies of intravenous recombinant tissue-type plasminogen activator (r-tPA) alone versus combined intravenous r-tPA/endovascular therapy in a subgroup of patients with large vessel (internal carotid artery terminus, M1, and M2) occlusion based on varying times to angiographic reperfusion and ...
Bonebrake Timothy C TC Department of Earth Sciences, School of Biological Sciences, University of Hong Kong, Pokfulam Road, Hong Kong SAR, Hong Kong - - 2014
Difficulty in characterizing the relationship between climatic variability and climate change vulnerability arises when we consider the multiple scales at which this variation occurs, be it temporal (from minute to annual) or spatial (from centimetres to kilometres). We studied populations of a single widely distributed butterfly species, Chlosyne lacinia, to ...
Wei Junying - - 2014
Evaluating the safety of traditional medicinal herbs and their major active constituents is critical for their widespread usage. Geniposide, a major active constituent with a defined structure from the traditional medicinal herb Gardenia jasminoides ELLIS fruit, exhibits remarkable anti-inflammatory, anti-apoptotic and antifibrotic properties and has been used in a variety ...
Owens Katie H KH School of Pharmacy, University of Otago, Dunedin, New - - 2014
Paracetamol is one of the most common pharmaceutical agents taken in self-poisonings and may increase the prothrombin time (PT) through liver injury, and in overdose without hepatic injury by reducing functional factor VII [1-4]. PT is a measure of hepatic injury used to predict and monitor hepatotoxicity, reported as the ...
Meyer-Baese Anke A Department of Scientific Computing, Florida State University, - - 2014
The interpretation of phosphoproteomics data sets is crucial for generating hypotheses that guide therapeutic solutions, yet not many techniques have been applied to this type of analysis. This paper intends to give an overview about the two main standard techniques that can be applied to the analysis of these large ...
Wang Chen C a School of Transportation Engineering , Tongji University , 4800 Cao'an Road, Shanghai 201804 , China ., Phone: +86-18221148065 Email: - - 2014
ABSTRACT Objectives This study investigated factors correlated with the severity of injuries sustained by bicyclists in bicycle-motor vehicle crashes at unsignalized intersections to develop site-specific countermeasures and interventions to improve bicycle safety. Method Crash data were extracted from accident reports entered into the Kentucky State Police's Kentucky Collision Database in ...
Pretz Christopher R CR Craig Hospital, Englewood CO; Traumatic Brain Injury National Data and Statistical Center, Englewood CO. Electronic address: - - 2014
To verify that iterative proportional fitting (IPF) or raking has the desired effect of aligning estimates and parameters so that researches have confidence in population projections when weighting the Traumatic Brian Injury (TBI) Model Systems National Database. Secondary data analysis using IPF. Inpatient rehabilitation. People age 16 and over with ...
Kong Guilan G Peking University, - - 2014
Peking University has several prestigious teaching hospitals in China. To make secondary use of massive medical data for research purposes, construction of a clinical data warehouse is imperative in Peking University. However, a big concern for clinical data warehouse construction is how to protect patient privacy. In this project, we ...
Spiriti Justin J Department of Computational and Systems Biology, University of Pittsburgh , Pittsburgh, Pennsylvania 15213, United - - 2014
Many commonly used coarse-grained models for proteins are based on simplified interaction sites and consequently may suffer from significant limitations, such as the inability to properly model protein secondary structure without the addition of restraints. Recent work on a benzene fluid (Lettieri S.; Zuckerman D. M.J. Comput. Chem.2012, 33, 268-275) ...
Díaz J I JI Instituto de Matemática Interdisciplinar and Dept. Mat. Aplicada , Universidad Complutense de Madrid , 28040 Madrid, - - 2014
We study a climatologically important interaction of two of the main components of the geophysical system by adding an energy balance model for the averaged atmospheric temperature as dynamic boundary condition to a diagnostic ocean model having an additional spatial dimension. In this work, we give deeper insight than previous ...
Sundararaman Ravishankar R Department of Physics, Cornell University, Ithaca, New York 14853, - - 2014
Continuum solvation models enable efficient first principles calculations of chemical reactions in solution, but require extensive parametrization and fitting for each solvent and class of solute systems. Here, we examine the assumptions of continuum solvation models in detail and replace empirical terms with physical models in order to construct a ...
Inan Omer - - 2014
In the past decade, there has been a resurgence in the field of unobtrusive cardiomechanical assessment, through advancing methods for measuring and interpreting ballistocardiogram (BCG) and seismocardiogram (SCG) signals. Novel instrumentation solutions have enabled BCG and SCG measurement outside of clinical settings: in the home, in the field, and even ...
Miqueles E X EX CNPEM/LNLS, Brazilian Synchrotron Light Laboratory, Campinas, São Paulo, - - 2014
A fast algorithm for ring artefact reduction in high-resolution micro-tomography with synchrotron radiation is presented. The new method is a generalization of the one proposed by Titarenko and collaborators, with a complete sinogram restoration prior to reconstruction with classical algorithms. The generalized algorithm can be performed in linear time and ...
Paniello Randal C RC Department of Otolaryngology-Head and Neck Surgery, Washington University, St. Louis, Missouri, U.S.A; the St. Louis Veterans Affairs Medical Center, St. Louis, Missouri, - - 2014
Most patients with unilateral vocal fold paralysis experience some degree of spontaneous reinnervation, which depends upon the type and severity of recurrent laryngeal nerve (RLN) injury. After partial recovery, the paretic vocal fold may or may not adduct adequately to allow glottic closure, which in turn affects phonatory and swallowing ...
Petraglia Anthony L AL *Department of Neurosurgery, Rochester Regional Health System, Rochester, New York; ‡Department of Neurological Surgery, University of Rochester Medical Center, Rochester, New York; §Department of Neurosurgery, The Center for Neuroscience, West Virginia University School of Medicine, Morgantown, West Virginia; and ¶Department of Neurosurgery, NorthShore University Health System, Evanston, Illinois and Department of Neurosurgery, University of Chicago Pritzker School of Medicine, Chicago, - - 2014
: Mild traumatic brain injury (TBI) has become a rising epidemic, affecting millions of people each year. Even though it is the most common type of brain injury, our understanding of the science underlying mild TBI is just in its infancy. There has been an explosion of basic science research ...
Gunning Amy C AC From the Department of Trauma Surgery, University Medical Center Utrecht, Utrecht, the - - 2014
The extensively used trauma scores to evaluate trauma center performances have been derived decades ago. This leaves its applicability in the current trauma population a subject of discussion.In this study, we evaluate the applicability of the current trauma scores in today's trauma population. This study was performed in the central ...
Ackleh Azmy S AS a Department of Mathematics , University of Louisiana at Lafayette , Lafayette , LA 70504 , - - 2014
We present a second-order high-resolution finite difference scheme to approximate the solution of a mathematical model of the transmission dynamics of Mycobacterium marinum (Mm) in an aquatic environment. This work extends the numerical theory and continues the preliminary studies on the model first developed in Ackleh et al. [Structured models ...
Xu Ye Y MOE Key Laboratory of Regional Energy and Environmental Systems Optimization, Sino-Canada Resources and Environmental Research Academy, North China Electric Power University , Beijing, China - - 2014
In this study, a fuzzy robust optimization (FRO) model was developed for supporting municipal solid waste management under uncertainty. The Development Zone of the City of Dalian, China, was used as a study case for demonstration. Comparing with traditional fuzzy models, the FRO model made improvement by considering the minimization ...
Danelson Kerry - - 2014
The purpose of this study was to compare the response of the Total HUman Model for Safety (THUMS) total body finite element model to experimental Post Mortem Human Subject (PMHS) test results and evaluate possible injuries caused by suit ring elements. Experimental testing evaluated the PMHS response in frontal, rear, ...
Leonhardt G G Unit of Environmental Engineering, Institute of Infrastructure Engineering, University of Innsbruck, Technikerstrasse 13, A 6020 Innsbruck, Austria E-mail: - - 2014
The performance assessment of storage tanks and combined sewer overflow (CSO) structures in sewer systems requires knowledge of the total inflow from the catchment during rainfall events. Many structures are, however, only equipped with sensors to measure water level and/or outflows. Based on the geometry of the tank, expressed as ...
Huang Wuhuang W School of Automation Engineering, University of Electronic Science and Technology of China, Chengdu 611731, - - 2014
Parallelism-based technique of time-interleaved analog-to-digital conversion (TIADC) has become an effective solution for the higher sampling rate acquisition system to acquire non-repetitive waveforms. With the increase of sampling frequency, the indeterminacy of combining sequence of sampled data among multiple components has become a highlighted barrier for the reset operation of ...
Pushpalatha Hulikal Basavarajaiah HB Formulation and Development, Research and Development Center, The Himalaya Drug Company, Makali, Bengaluru, - - 2014
Irradiation and use of preservatives are routine procedures to control bio-burden in solid herbal dosage forms. Use of steam or pasteurization is even though reported in the literature, not many studies are available with respect to its application in reducing the bio-burden in herbal drug formulations. Hence, we undertook a ...
Fu Qirang Q Key Laboratory of Energy Thermal Conversion and Control of Ministry of Education, Southeast University, Nanjing, - - 2014
Thermo-chemical gasification of sawdust refuse-derived fuel was performed on a bench-scale fluidised bed gasifier with enriched air and steam as fluidising and oxidising agents. Dolomite as a natural mineral catalyst was used as bed material to reform tars and hydrocarbons. A series of experiments were carried out under typical operating ...
Mulkern Edward M EM Sheffield Vascular Institute, Northern General Hospital, Sheffield, United Kingdom - - 2014
Experimental models of recovery from limb ischemia are required for evaluating novel means of treating ischemia. We describe a mouse model to assess gait after inducing limb ischemia. Gait analysis was performed using a Plexiglass tube, the floor of which contained load cells. Gait was measured in 20 mice; 10 ...
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