Search Results
Results 401 - 450 of 2850
< 4 5 6 7 8 9 10 11 12 13 14 >
Yan Xin - - 2013
Shape comparing technologies based on Gaussian functions have been widely used in virtual screening of drug discovery. For efficiency, most of them adopt the First Order Gaussian Approximation (FOGA), in which the shape density of a molecule is represented as a simple sum of all individual atomic shape densities. In ...
Sica G - - 2013
Exposure-response relationships are important tools for policy makers to assess the impact of an environmental stressor on the populace. Their validity lies partly in their statistical strength which is greatly influenced by the size of the sample from which the relationship is derived. As such, the derivation of meaningful exposure-response ...
Altiparmak Mehmet Riza - - 2013
Abstract We aimed to investigate the performance of various creatinine based glomerular filtration rate estimation equations that were widely used in clinical practice in Turkey and calculate a correction coefficient to obtain a better estimate using the isotope dilution mass spectrometry (IDMS)-traceable Modification of the Diet in Renal Disease (MDRD) ...
Jovanović Marija - - 2013
The objective of the study was to develop population pharmacokinetic model of topiramate (TPM) using nonlinear mixed effects modelling approach. Data were collected from 78 adult epilepsy patients on mono- or co-therapy of TPM and other antiepileptic drugs, such as carbamazepine (CBZ), valproic acid, lamotrigine, levetiracetam, phenobarbital and pregabalin. Steady-state ...
Cella Laura - - 2013
To establish a multivariate normal tissue complication probability (NTCP) model for radiation-induced asymptomatic heart valvular defects (RVD). Fifty-six patients treated with sequential chemoradiation therapy for Hodgkin lymphoma (HL) were retrospectively reviewed for RVD events. Clinical information along with whole heart, cardiac chambers, and lung dose distribution parameters was collected, and ...
Hennebelle F - - 2013
The straightness error of a coordinate measuring machine (CMM) is determined by measuring a rule standard. Thanks to a reversal technique, the straightness uncertainty of the CMM is theoretically dissociated from the straightness uncertainty of the rule. However, stochastic variations of the whole measurement system involve uncertainties of the CMM ...
Beck T R - - 2013
This paper analyses the data having been gathered from interlaboratory comparisons of passive radon instruments over 10 y with respect to the measurement accuracy. The measurement accuracy is discussed in terms of the systematic and the random measurement error. The analysis shows that the systematic measurement error of the most ...
Zhang Qian - - 2013
Conformational entropy calculation, usually computed by normal mode analysis (NMA) or quasi harmonic analysis (QHA), is extremely time-consuming. Here, instead of NMA or QHA, a solvent accessible surface area (SASA) based model was employed to compute the conformational entropy, and a new fast GPU-based method called MURCIA (Molecular Unburied Rapid ...
Kramer M - - 2013
The aim of this study was to estimate genetic parameters and accuracies of breeding values for a set of functional, behavior, and conformation traits in Brown Swiss cattle. These traits were milking speed, udder depth, position of labia, rank order in herd, general temperament, aggressiveness, milking temperament, and days to ...
Vandekerckhove Frank - - 2013
Aims: We define criteria to predict the number of mature oocytes using automated three-dimensional (3D) ultrasound follicle measurements. Methods: Fifty in vitro fertilization/intracytoplasmic sperm injection patients underwent automated 3D echographic monitoring by a single researcher following the stimulation procedure. Classic criteria for triggering oocyte maturation as defined in the literature ...
Salamh Paul A - - 2013
Abstract Purpose: To investigate the reliability, minimal detectable change (MDC90) and concurrent validity of a gravity-based bubble inclinometer (inclinometer) and iPhone® application for measuring standing lumbar lordosis. Methods: Two investigators used both an inclinometer and an iPhone® with an inclinometer application to measure lumbar lordosis of 30 asymptomatic participants. Results: ...
Heusch Philipp - - 2013
Biexponential analysis has been used increasingly to obtain contributions of both diffusion and microperfusion to the signal decay in diffusion-weighted imaging DWI of different parts of the body. To compare biexponential diffusion parameters of transplanted kidneys obtained with three different calculation methods. DWI was acquired in 15 renal allograft recipients ...
Lee Wook - - 2013
Early detection of Alzheimer's disease (AD) is important since treatments are more efficacious when used at the beginning of the disease. Despite significant advances in diagnostic methods for AD, there is no single diagnostic method for AD with high accuracy. We developed a support vector machine (SVM) model that classifies ...
Leistritz L - - 2013
For the past decade, the detection and quantification of interactions within and between physiological networks has become a priority-in-common between the fields of biomedicine and computer science. Prominent examples are the interaction analysis of brain networks and of the cardiovascular-respiratory system. The aim of the study is to show how ...
Zhang Xinghua - - 2013
This paper proposes a semi-empirical method to reconstruct daily ultraviolet (UV) radiation from global solar (G) radiation measurements using a radiative transfer model. The attenuation ratio and cloud modification factors are calculated based on measured and simulated data under cloudless-sky conditions. A reconstruction method of UV radiation is established using ...
Talma H - - 2013
Bioelectrical impedance analysis (BIA) is a practical method to estimate percentage body fat (%BF). In this systematic review, we aimed to assess validity, responsiveness, reliability and measurement error of BIA methods in estimating %BF in children and adolescents.We searched for relevant studies in Pubmed, Embase and Cochrane through November 2012. ...
Vu Truong Nguyen Luan - - 2013
A new design method of fractional-order proportional-integral controllers is proposed based on fractional calculus and Bode's ideal transfer function for a first-order-plus-dead-time process model. It can be extended to be applied to various dynamic models. Tuning rules were analytically derived to cope with both set-point tracking and disturbance rejection problems. ...
Martínez-García Roberto - - 2013
There is an agreement to use simple formulae (expected bladder capacity and other age based linear formulae) as bladder capacity benchmark. But real normal child's bladder capacity is unknown. To offer a systematic review of children's normal bladder capacity, to measure children's normal maximum voided volumes (MVVs), to construct models ...
Qu Xiaohui - - 2013
The rapid access to intrinsic physicochemical properties of molecules is highly desired for large scale chemical data mining explorations such as mass spectrum prediction in metabolomics, toxicity risk assessment and drug discovery. Large volumes of data are being produced by quantum chemistry calculations, which provide increasing accurate estimations of several ...
Bernau Christoph - - 2013
High-dimensional binary classification tasks, for example, the classification of microarray samples into normal and cancer tissues, usually involve a tuning parameter. By reporting the performance of the best tuning parameter value only, over-optimistic prediction errors are obtained. For correcting this tuning bias, we develop a new method which is based ...
Leung Denis Heng-Yan - - 2013
The method of generalized estimating equations (GEE) is a popular tool for analysing longitudinal (panel) data. Often, the covariates collected are time-dependent in nature, for example, age, relapse status, monthly income. When using GEE to analyse longitudinal data with time-dependent covariates, crucial assumptions about the covariates are necessary for valid ...
Boethling Robert - - 2013
Organosilicon compounds are important in chemistry and commerce, and nearly 10% of new chemical substances for which Premanufacture Notifications (PMNs) are processed by the US EPA contain Si. Despite this, remarkably few measured values are submitted for key physical properties, and the accuracy of estimation programs like the Estimation Programs ...
Rao Xiayu - - 2013
Abstract Quantitative real-time polymerase chain reaction (qPCR) is a sensitive gene quantification method that has been extensively used in biological and biomedical fields. The currently used methods for PCR data analysis, including the threshold cycle method and linear and nonlinear model-fitting methods, all require subtracting background fluorescence. However, the removal ...
Prisco Michael R - - 2013
Container closure integrity is a critical factor for maintaining product sterility and stability. Therefore, closure systems (found in vials, syringes, and cartridges) are designed to provide a seal between rubber stoppers and glass containers. To ensure that the contained product has maintained its sterility and stability at the time of ...
Aguila-Camacho Norelys - - 2013
This paper presents the application of a direct Fractional Order Model Reference Adaptive Controller (FOMRAC) to an Automatic Voltage Regulator (AVR). A direct FOMRAC is a direct Model Reference Adaptive Control (MRAC), whose controller parameters are adjusted using fractional order differential equations. Four realizations of the FOMRAC were designed in ...
Cohen Ariel - - 2013
Pedestrians account for 10-30% of all road accident fatalities in western countries, and therefore efforts to improve pedestrian safety are of major importance. Research can support these efforts in various ways, particularly by studying road crossing patterns, and by exploring pedestrian compliance rates to safety laws and guidelines. This paper ...
Botelho Anabela - - 2013
This study empirically evaluates whether the increasingly large numbers of private outpatient healthcare facilities (HCFs) within the European Union (EU) countries comply with the existing European waste legislation, and whether compliance with such legislation affects the fraction of healthcare waste (HCW) classified as hazardous. To that end, this study uses ...
Lemley Kevin V - - 2013
The podocyte depletion hypothesis has emerged as an important unifying concept in glomerular pathology. The estimation of podocyte number is therefore often a critical component of studies of progressive renal diseases. Despite this, there is little uniformity in the biomedical literature with regard to the methods used to estimate this ...
Zhang Yinwang - - 2013
It remains rare to report three-dimensional (3-D) finite element solid model of femurs in partial by volume rendering method, though several methods of femoral 3-D finite element modeling are already available. We aim to analyze the advantages of the modeling method by establishing the 3-D finite element solid model of ...
Warner D - - 2013
Fractional passage rates form a fundamental element within modern feed evaluation systems for ruminants but knowledge on feed type and feed component specific passage rates are largely lacking. This study describes the use of carbon stable isotopes ((13)C) to assess component-specific passage kinetics of 6 intrinsically (13)C-labeled corn silages varying ...
Zoffoli Hugo José Oliveira - - 2013
In environmental monitoring, variables with analytically non-detected values are commonly encountered. For the statistical evaluation of these data, most of the methods that produce a less biased performance require specific computer programs. In this paper, a statistical method based on the median semi-variance (SemiV) is proposed to estimate the position ...
Goñi Joaquín - - 2013
High-resolution isotropic three-dimensional reconstructions of human brain gray and white matter structures can be characterized to quantify aspects of their shape, volume and topological complexity. In particular, methods based on fractal analysis have been applied in neuroimaging studies to quantify the structural complexity of the brain in both healthy and ...
Thorup V M - - 2013
Existing methods for estimating individual dairy cow energy balance typically either need information on feed intake, that is, the traditional input-output method, or frequent measurements of BW and body condition score (BCS), that is, the body reserve changes method (EBbody). The EBbody method holds the advantage of not requiring measurements ...
Walczak-Jedrzejowska Renata - - 2013
The aim of the study was to determine the degree of compliance of Polish laboratories with World Health Organization (WHO) recommendations, with regard to semen analysis methodology. A survey requesting information about methods of semen analysis was distributed to employees of 55 laboratories. Respondents who had participated in external seminological ...
Bendel David - - 2013
In the presented study climate change impacts on combined sewer overflows (CSOs) in Baden-Wuerttemberg, Southern Germany, were assessed based on continuous long-term rainfall-runoff simulations. As input data, synthetic rainfall time series were used. The applied precipitation generator NiedSim-Klima accounts for climate change effects on precipitation patterns. Time series for the ...
Nordenskjöld Richard - - 2013
In brain volumetric studies, intracranial volume (ICV) is often used as an estimate of pre-morbid brain size as well as to compensate for inter-subject variations in head size. However, if the estimated ICV is biased by for example gender or atrophy, it could introduce errors in study results. To evaluate ...
Ke Tingting - - 2013
The estimation of the groundwater recharge in a karstic system becomes an important challenge due to the great hydrodynamic variability in both time and space. This paper proposes a two reservoir conceptual model to simulate inflow into both the conduit system and the fissure network system based on the analysis ...
Schlebusch Thomas - - 2013
Ubiquitous knowledge of bladder volume is of great interest to patients whose perception of bladder volume is impaired. A promising approach to provide frequent bladder volume estimates to the patient are automatic and noninvasive measurements by electrical impedance tomography (EIT). Previous studies have shown a linear correlation of abdominal electrical ...
Alipoor Mohammad - - 2013
Diffusion weighted magnetic resonance imaging (dMRI) is used to measure, in vivo, the self-diffusion of water molecules in biological tissues. High order tensors (HOTs) are used to model the apparent diffusion coefficient (ADC) profile at each voxel from the dMRI data. In this paper we propose: (i) A new method ...
Caune Vairis - - 2013
This paper aims at exploring the feasibility of a brain source localization method from intracerebral stereo-electroencephalography (SEEG) measurements. The SEEG setup consists in multi-contact electrodes inserted in the brain volume, each containing about 10 collinear measuring contacts. In clinical context, these signals are usually observed using a bipolar montage (potential ...
Kim Tae-Ho - - 2013
In this paper, a cepstral analysis based approach to measuring the depth of anesthesia (DoA) is presented. Cepstral analysis is a signal processing technique widely used especially for speech recognition in order to extract speech information regardless of vocal cord characteristics. The resulting index for the DoA is called index ...
Corona-Strauss F I - - 2013
Auditory Brainstem Responses (ABRs) are commonly used in clinical practice to determine hearing impairments and hearing thresholds. Although many research groups work on automatic recognition of ABRs - in order to decrease the acquisition times - measures to determine the quality of ABR measurements objectively are still missing. In fact, ...
Lien Yu-An S - - 2013
Relative fundamental frequency (RFF), defined as the normalized fundamental frequencies of vowels surrounding voiceless consonants, has been shown to have a characteristic pattern in healthy voices that differs from those with disordered voices (e.g. vocal hyperfunction, Parkinson's disease). However no large-scale clinical study has been performed, mainly because the current ...
Zhu Fansan - - 2013
Knowledge of dynamics of shift of fluid volume between intra- and extravascular compartments during hemodialysis (HD) is important for managing HD treatment to help patients approach dry weight without hypotension. The Relative blood volume (RBV) monitor indicates change in plasma volume based on the difference between ultrafiltration rate (UFR) and ...
Shi Li-Chen - - 2013
Feature dimensionality reduction methods with robustness have a great significance for making better use of EEG data, since EEG features are usually high-dimensional and contain a lot of noise. In this paper, a robust principal component analysis (PCA) algorithm is introduced to reduce the dimension of EEG features for vigilance ...
Mirzaalian Hengameh - - 2013
We propose a top-down fully automatic 3D vertebra segmentation algorithm using global shape-related as well as local appearance-related prior information. The former is brought into the system by a global statistical shape model built from annotated training data, i.e., annotated CT volumes. The latter is handled by a machine learning-based ...
Despotovic Ivana - - 2013
Developing a realistic volume conductor head model is an important step towards a non-invasive investigation of neuro-electrical activity in the brain. For adults, different volume conductor head models have been designed and successfully used for electroencephalography (EEG) source analysis. However, creating appropriate neonatal volume conductor head model for EEG source ...
Hegde Chethan - - 2013
To ascertain the use of nasion as a guide in locating the position of orbitale as an anterior reference point in the face-bow transfer records in individuals having different facial types. This study evaluated the distance from the nasion to the orbitale using cephalometric measurements to ascertain the use of ...
Chegal Won - - 2013
We developed a multichannel three-polarizer spectroscopic ellipsometer based on a data acquisition algorithm for achieving optimized precision. This algorithm measures unnormalized Fourier coefficients accurately and precisely. Offset angles for optical elements were obtained as wavelength-independent values using regression calibration. Derived subsets of data reduction functions were used to calculate sample ...
Huang Mian - - 2013
Motivated by an analysis of US house price index data, we propose nonparametric finite mixture of regression models. We study the identifiability issue of the proposed models, and develop an estimation procedure by employing kernel regression. We further systematically study the sampling properties of the proposed estimators, and establish their ...
< 4 5 6 7 8 9 10 11 12 13 14 >