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Results 301 - 350 of 2868
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Howe Laura D - - 2013
Childhood growth is of interest in medical research concerned with determinants and consequences of variation from healthy growth and development. Linear spline multilevel modelling is a useful approach for deriving individual summary measures of growth, which overcomes several data issues (co-linearity of repeat measures, the requirement for all individuals to ...
Stroom Joep - - 2013
To develop a combined recipe for clinical target volume (CTV) and planning target volume (PTV) margins. A widely accepted PTV margin recipe is Mgeo = aΣgeo + bσgeo, with Σgeo and σgeo standard deviations (SDs) representing systematic and random geometric uncertainties, respectively. On the basis of histopathology data of breast ...
Rex Douglas K - - 2013
Endoscopic measurement of colorectal polyps by using open forceps is commonly used in clinical trials but is subject to several sources of error. Assess error rates in polyp size determination with open forceps at the step of measurement after the forceps are aligned on the polyp. This was a prospective assessment ...
Szczesniak Rhonda D - - 2013
Detecting the onset of rapid lung function decline is important to reduce mortality rates in cystic fibrosis (CF) and other lung diseases. The most common approach is conventional linear mixed modeling-estimating a population-level slope of lung function decline and using random effects to address serial correlation-but this ignores nonlinear features ...
Smith Alastair D - - 2013
Efficient daily navigation is underpinned by path integration, the mechanism by which we use self-movement information to update our position in space. This process is well understood in adulthood, but there has been relatively little study of path integration in childhood, leading to an underrepresentation in accounts of navigational development. ...
Cladière Mathieu - - 2013
Assessing the fate of endocrine disrupting compounds (EDCs) in the environment is currently a key issue for determining their impacts on aquatic ecosystems. The 4-nonylphenol (4-NP) is a well known EDC and results from the biodegradation of surfactant nonylphenol ethoxylates (NPnEOs). Fate mechanisms of NPnEO are well documented but their ...
Prilepov Iuri - - 2013
Multifluid simulations often create volume fraction data, representing fluid volumes per region or cell of a fluid data set. Accurate and visually realistic extraction of fluid boundaries is a challenging and essential task for efficient analysis of multifluid data. In this work, we present a new material interface reconstruction method ...
Zhao Yue - - 2013
This article proposes a robust technique for needle detection and tracking using three-dimensional ultrasound (3D US). It is difficult for radiologists to detect and follow the position of micro tools, such as biopsy needles, that are inserted in human tissues under 3D US guidance. To overcome this difficulty, we propose ...
Hermida-López M - - 2013
Purpose: For decades, (106)Ru∕(106)Rh ophthalmic applicators have been widely used to treat intraocular malignancies with good clinical outcomes. Determining the dosimetry of such applicators is challenging because of their spherical shape, the low range of emitted betas and the steep gradients involved. Furthermore, there is a lack of dose distribution ...
Chung Yeojin - - 2013
Group-level variance estimates of zero often arise when fitting multilevel or hierarchical linear models, especially when the number of groups is small. For situations where zero variances are implausible a priori, we propose a maximum penalized likelihood approach to avoid such boundary estimates. This approach is equivalent to estimating variance ...
de Water Valerie R - - 2013
To test the accuracy and reliability of Dolphin 3-dimensional (3D) software airway analysis compared with manual segmentation in patients who underwent a Le Fort III osteotomy. Computed tomographic scans of 20 patients with syndromic craniosynostosis at Sophia's Children's Hospital (Rotterdam, The Netherlands) were used for airway volume measurements using Dolphin ...
Ballard Megan S - - 2013
A method to estimate source range in environments that exhibit three-dimensional propagation effects is presented. A hybrid modeling technique using vertical modes and horizontal rays is employed. Results are obtained in a computationally efficient manner and require limited knowledge of the environment. The method is applied to data recorded on ...
Marti Amparo - - 2013
Source localization using the steered response power (SRP) usually requires a costly grid-search procedure. To address this issue, a modified SRP algorithm was recently introduced, providing improved robustness when using coarser spatial grids. In this letter, an iterative method based on the modified SRP is presented. A coarse spatial grid ...
Lei Yunwen - - 2013
In this paper, the problem of learning the functional dependency between input and output variables from scattered data using fractional polynomial models (FPM) is investigated. The estimation error bounds are obtained by calculating the pseudo-dimension of FPM, which is shown to be equal to that of sparse polynomial models (SPM). A linear ...
Stavinoha Amanda - - 2013
Maintaining a dialysis patient's hemoglobin (Hgb) within a very narrow range can be challenging. Relying on Hgb measurements only once or twice a month can cause large fluctuations in their measurements. Utilizing the Hgb measurement from noninvasive modalities has been studied in adult populations. Our study focused on a pediatric ...
Brown Albert - - 2013
We describe a Monte Carlo renormalization group approach to the calculation of critical behavior for percolation models. This approach can be utilized to determine the renormalized bond probabilities and the values of the critical exponents. We illustrate the method for two-dimensional bond percolation, but the method is also applicable to ...
Hadeler Karl Peter - - 2013
The Michaelis-Menten (MM) function is a fractional linear function depending on two positive parameters. These can be estimated by nonlinear or linear least squares methods. The non-linear methods, based directly on the defect of the MM function, can fail and not produce any minimizer. The linear methods always produce a ...
Habibi Ehsanollah E Department of Health, Isfahan University of Medical Sciences, Isfahan, - - 2013
Various studies carried out on different photo anthropometry, but each one had some deficiencies which during the years they have been resolved. The objective of this paper is to test the efficiency of two-dimensional image processing software in photo anthropometry of hand. In this applied research, 204 office workers and ...
Papadimitriou Vassileios C - - 2013
The atmospheric processing of (E)- and (Z)-1,2-dichlorohexafluoro-cyclobutane (1,2-c-C4F6Cl2, R-316c) was examined in this work as the ozone depleting (ODP) and global warming (GWP) potentials of this proposed replacement compound are presently unknown. The predominant atmospheric loss processes and infrared absorption spectra of the R-316c isomers were measured to provide a ...
Muy S - - 2013
We show how to extract an estimate of the entropy production from a sufficiently long time series of stationary fluctuations of chemical reactions. This method, which is based on recent work on fluctuation theorems, is direct, non-invasive, does not require any knowledge about the underlying dynamics and is applicable even ...
Li Min - - 2013
The genotoxicity of 21 quinolones antibiotics was determined using SOS/umu assay. Some quinolones exhibited high genotoxicity, and the chemical substituent on quinolone ring significantly affected genotoxicity. To establish the relationship between genotoxicity and substituent, a 2D-QSAR model based on quantum chemical parameters was developed. Calculation suggested that both steric and ...
Ben Mohammadi Lhoucine - - 2013
In this paper we describe the concept and in vivo results of a minimally invasive, chip-based near infrared (NIR) sensor, combined with microdialysis, for continuous glucose monitoring. The sensor principle is based on difference absorption spectroscopy in selected wavelength bands of the near infrared spectrum (1300nm, 1450nm, and 1550nm) in ...
Jones Sarah M - - 2013
We investigated the precision of the approximate number system (ANS) in three lemur species (Lemur catta, Eulemur mongoz, and Eulemur macaco flavifrons), one Old World monkey species (Macaca mulatta) and humans (Homo sapiens). In Experiment 1, four individuals of each nonhuman primate species were trained to select the numerically larger ...
Carreer William J WJ Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, KY 40536, USA; jim.carreer@uky.edu (W.J.C.); robert.flight@uky.edu - - 2013
New metabolomics applications of ultra-high resolution and accuracy mass spectrometry can provide thousands of detectable isotopologues, with the number of potentially detectable isotopologues increasing exponentially with the number of stable isotopes used in newer isotope tracing methods like stable isotope-resolved metabolomics (SIRM) experiments. This huge increase in usable data requires ...
Hermans Denise J J - - 2013
Accurate and objective measurement of volume changes in infantile hemangiomas (IHs) is essential in routine clinical practice and clinical studies, particularly in the changing therapeutic landscape after the discovery of propranolol. Several bedside techniques for volume measurement have been described in the literature, but an objective method of measurement of ...
Zandkarimi Majid M Department of Pharmaceutical Sciences, School of Pharmacy, Zabol University of Medical Sciences, Zabol, - - 2014
An important goal for drug development within the pharmaceutical industry is the application of simple methods to determine human pharmacokinetic parameters. Effective computing tools are able to increase scientists' ability to make precise selections of chemical compounds in accordance with desired pharmacokinetic and safety profiles. This work presents a method ...
Sheu Tommy - - 2013
To test the appropriateness of the linear-quadratic (LQ) model to describe survival of jejunal crypt clonogens after split doses with variable (small 1-6Gy, large 8-13Gy) first dose, as a model of its appropriateness for both small and large fraction sizes. C3Hf/KamLaw mice were exposed to whole body irradiation using 300kVp ...
Chen Xiuguo - - 2013
Library search is one of the most commonly used methods for solving the inverse problem in optical scatterometry. The final measurement accuracy of the conventional library search method highly depends on the grid interval selected for each parameter in the signature library, and the time cost of the parameter extraction ...
Hu Haofeng - - 2013
We address the estimation of the Stokes vectors taking into account the physical realizability constraint. We propose a fast method for computing the constrained maximum-likelihood (CML) estimator for any measurement matrix, and we compare its performance with the classical empirical physicality-constrained estimator. We show that when the measurement matrix is ...
Tie Guipeng - - 2013
Considering the wavefront error of KH<sub>2</sub>PO<sub>4</sub> (KDP) crystal is difficult to control through face fly cutting process because of surface shape deformation during vacuum suction, an error compensation technique based on a spiral turning method is put forward. An in situ measurement device is applied to measure the deformed surface ...
Rucker Daniel - - 2013
In open abdominal image-guided liver surgery, sparse measurements of the organ surface can be taken intraoperatively via a laser-range scanning device or a tracked stylus with relatively little impact on surgical workflow. We propose a novel nonrigid registration method which uses sparse surface data to reconstruct a mapping between the ...
Zuber Claudia - - 2013
Abstract Researchers largely agree that there is a positive relationship between achievement motivation and athletic performance, which is why the achievement motive is viewed as a potential criterion for talent. However, the underlying mechanism behind this relationship remains unclear. In talent and performance models, main effect, mediator and moderator models ...
Meldrum Dara - - 2013
Estimating the measurement error (reliability) of three dimensional gait analysis (3DGA) is crucial to interpretation of gait data. The purpose of this study was to investigate the intra-rater reliability of 3DGA and apply a novel method of visualising reliability of gait cycle waveforms. A test re-test design was employed. A ...
Preiss Ulrich P - - 2013
We show for the first time that a phenomenological, augmented volume-based thermodynamics (aVBT) model is capable to predict the critical micelle concentrations of ionic surfactants, including ionic liquids, with added salts. The model also adjusts for the type of salt added by including its molecular volume, which might form a ...
Morris Carrie A - - 2013
Despite the important role of the antimalarial artesunate, and its active metabolite dihydroartesmisinin (DHA), in malaria treatment efforts, there are limited data on the pharmacokinetics of these agents in pediatric patients. This study evaluated the effects of body size and gender on the pharmacokinetics of artesunate/DHA using data from pediatric ...
Parvizi Daryousch - - 2013
Accurate estimation of burn size is of critical importance, as it is incorporated in every resuscitation formula. The aim of this study was to investigate total burn surface area (TBSA) accuracy among burn specialists, evaluate the potential impact of incorrect evaluation on variations of resultant fluid resuscitation volumes and to ...
Ingram David G - - 2013
Patients with Willis-Ekbom disease (restless legs syndrome [RLS]) frequently report seasonal worsening of their symptoms; however, seasonal patterns in this disorder have not been systematically evaluated. The purpose of our investigation was to utilize Internet search query data to test the hypothesis that restless legs symptoms vary by season, with ...
Holz Elisa Mira - - 2013
Connect-Four, a new sensorimotor rhythm (SMR) based brain-computer interface (BCI) gaming application, was evaluated by four severely motor restricted end-users; two were in the locked-in state and had unreliable eye-movement. Following the user-centred approach, usability of the BCI prototype was evaluated in terms of effectiveness (accuracy), efficiency (information transfer rate ...
Eckert Andrew J - - 2013
Estimates from molecular data for the fraction of new nonsynonymous mutations that are adaptive vary strongly across plant species. Much of this variation is due to differences in life history strategies as they influence the effective population size (Ne ). Ample variation for these estimates, however, remains even when comparisons ...
Magis David - - 2013
In item response theory, the classical estimators of ability are highly sensitive to response disturbances and can return strongly biased estimates of the true underlying ability level. Robust methods were introduced to lessen the impact of such aberrant responses on the estimation process. The computation of asymptotic (i.e., large-sample) standard ...
Sidick Erkin - - 2013
An adaptive periodic-correlation (APC) algorithm was developed for use in extended-scene Shack-Hartmann wavefront sensors. It provides high accuracy even when the subimages in a frame captured by a Shack-Hartmann camera are not only shifted but also distorted relative to each other. Recently we found that the shift estimate error of ...
Otte Willem M - - 2013
Focal epilepsy has recently been associated with remote white matter damage, including reduced white matter volume. Longitudinal assessment of these white matter changes, in relation to functional mechanisms and consequences, may be ideally done by in vivo neuroimaging in well-controlled experimental animal models. We assessed whether advanced machine learning algorithm ...
Pininski Melissa - - 2013
The accurate estimation of stature can meaningfully contribute to the positive identification of skeletal remains of unknown individuals. Regression equations are most commonly used to estimate stature and have been derived from numerous bones. Little is however known about stature estimation from the sacrum and therefore the aim of the ...
Keeler Bonnie L - - 2013
The Renewable Fuel Standard (RFS2) in the U.S. Energy Independence and Security Act of 2007 (EISA) sets annual volume targets for domestic renewable transportation fuel consumption through 2022, but allows for flexibility in the types of biomass used for biofuels and where and how they are grown. Spatially explicit feedstock ...
Geraci Marco - - 2013
A typical summary statistic for temporal trends is the average percent change (APC). The APC is estimated by using a generalized linear model, usually under the assumption of linearity on the logarithmic scale. A serious limitation of least-squares type estimators is their sensitivity to outliers. The goal of this study ...
Conde David - - 2013
Abstract Classification rules that incorporate additional information usually present in discrimination problems are receiving certain attention during the last years as they perform better than the usual rules. Fernández, M. A., C. Rueda and B. Salvador (2006): "Incorporating additional information to normal linear discriminant rules," J. Am. Stat. Assoc., 101, ...
Patouillard Edith - - 2013
There is increased interest in using commercial providers for improving access to quality malaria treatment. Understanding their current role is an essential first step, notably in terms of the volume of diagnostics and anti-malarials they sell. Sales volume data can be used to measure the importance of different provider and ...
Pearson Isobel - - 2013
Abstract Objective: The objective of the study was to conduct a systematic review of utility weight estimates relevant to economic models for wet age-related macular degeneration (wAMD). Methods: A systematic literature search of PubMed, Embase, the Cochrane Library, and EconLit was performed (January 1995-December 2010) and then updated (October 2010-May ...
Nawarathna Lakshika S - - 2013
We propose a methodology for evaluation of agreement between two methods of measuring a continuous variable whose variability changes with magnitude. This problem routinely arises in method comparison studies that are common in health-related disciplines. Assuming replicated measurements, we first model the data using a heteroscedastic mixed-effects model, wherein a ...
Burigana Luigi - - 2013
Given a set of points on the plane and an assignment of values to them, an optimal linear partition is a division of the set into two subsets which are separated by a straight line and maximally contrast with each other in the values assigned to their points. We present ...
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