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Weiss Michael M Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Naresuan, University, Phitsanulok, Thailand; Department of Pharmacology, Martin Luther University Halle-Wittenberg, Halle, Germany. Electronic address: - - 2014
A sum of two inverse Gaussian functions is proposed as a highly flexible empirical model for fitting of in vitro dissolution profiles. The model was applied to quantitatively describe theophylline release from effervescent multi-layer coated floating tablets containing different amounts of the anti-tacking agents talc or glyceryl monostearate. Model parameters ...
Hall Justin M JM Department of Orthopaedic Surgery and Biomedical Engineering, University of Tennessee-Campbell Clinic, Memphis, TN, - - 2014
We compared accuracy and reliability of a traditional method of measurement (most cephalad vertebral spinous process that can be reached by a patient with the extended thumb) to estimates made with the shoulder in abduction to determine if there were differences between the two methods. Six physicians with fellowship training ...
Kruisselbrink Richelle R From the Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada (R.K., R.E., V.C., A.P.); Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada (C.A.); and Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada - - 2014
Gastric sonography can provide information about gastric content and volume that can help determine aspiration risk at the bedside. The primary objective of this study is to assess the intrarater and interrater reliability of a previously validated method of gastric volume assessment based on gastric antral area. The secondary objective ...
Køppe Simo S Department of Psychology, Copenhagen University BabyLab, University of Copenhagen, Øster Farimagsgade 2A', Kbh. K, DK-1353, Copenhagen, Denmark, - - 2014
The evolution of developmental psychology has been characterized by the use of different quantitative and qualitative methods and procedures. But how does the use of methods and procedures change over time? This study explores the change and development of statistical methods used in articles published in Child Development from 1930 ...
Gönen Mehmet M Sage Bionetworks, Seattle, 98109 WA, - - 2014
Coupled training of dimensionality reduction and classification is proposed previously to improve the prediction performance for single-label problems. Following this line of research, in this paper, we first introduce a novel Bayesian method that combines linear dimensionality reduction with linear binary classification for supervised multilabel learning and present a deterministic ...
Kim Jae Seok JS Department of Nephrology, Yonsei University Wonju College of Medicine, 20 Ilsan-ro, Wonju 220-701, Korea. - - 2014
Purpose: Estimation of body fluid volume in hyponatremia is useful for diagnosis and therapeutic decision-making. Physical examination has been generally used to estimate body fluid volume, but it depends on the physician's abilities. Bioimpedance spectroscopy has been suggested to be a reliable method for the estimation of body fluid volume. ...
Gutierrez-Navarro Omar - - 2014
This paper proposes a new blind end-member and abundance extraction (BEAE) method for multispectral fluorescence lifetime imaging microscopy (m-FLIM) data. The chemometrical analysis relies on an iterative estimation of the fluorescence decay end-members and their abundances. The proposed method is based on a linear mixture model with positivity and sum-to-one ...
Etxaniz J J Department of Electronics Technology, University of the Basque Country, 48013 Bilbao, - - 2014
This Note introduces a novel methodology to analyze the time performance of Bluetooth gateways in multi-hop networks, known as scatternets. The methodology is focused on distinguishing between the processing time and the time that each communication between nodes takes along an implemented scatternet. This technique is not only valid for ...
Myhra S S Oxford University Begbroke Science Park, University of Oxford, Oxford, United - - 2014
A method for detection and characterization of single MeV α-particle and recoil tracks in PMMA photoresist by atomic force microscopy (AFM) analysis has been demonstrated. The energy deposition along the track is shown to lead to a latent pattern in the resist due to contrast reversal. It has been shown ...
Unlüer Erden E EE Izmir Katip Çelebi University Atatürk Research and Training Hospital, - - 2014
The objective of this study was to determine whether bedside visual estimates of left ventricular systolic function (LVSF) by emergency physicians (EP) would agree with quantitative measurement of LVSF by the modified Simpson's method (MSM), as recommended by the American Society of Echocardiography. After limited focused training, 2 trained EPs ...
Henrot Simon - - 2014
In this paper, we consider hyperspectral unmixing problems where the observed images are blurred during the acquisition process, e.g., in microscopy and spectroscopy. We derive a joint observation and mixing model and show how it affects end-member identifiability within the geometrical unmixing framework. An analysis of the model reveals that ...
Teka Wondimu W UTSA Neurosciences Institute, The University of Texas at San Antonio, San Antonio, Texas, United States of - - 2014
The voltage trace of neuronal activities can follow multiple timescale dynamics that arise from correlated membrane conductances. Such processes can result in power-law behavior in which the membrane voltage cannot be characterized with a single time constant. The emergent effect of these membrane correlations is a non-Markovian process that can ...
Medo Matúš M Physics Department, Chemin du Musée 3, University of Fribourg, 1700 Fribourg, - - 2014
The abundance of models of complex networks and the current insufficient validation standards make it difficult to judge which models are strongly supported by data and which are not. We focus here on likelihood maximization methods for models of growing networks with many parameters and compare their performance on artificial ...
Danaher Patrick P Department of Biostatistics, University of Washington, - - 2014
We consider the problem of estimating multiple related Gaussian graphical models from a high-dimensional data set with observations belonging to distinct classes. We propose the joint graphical lasso, which borrows strength across the classes in order to estimate multiple graphical models that share certain characteristics, such as the locations or ...
Glass-Kaastra Shiona K SK Public Health Agency of Canada, Centre for Food-borne, Environmental and Zoonotic Infectious Diseases, Guelph, - - 2014
Because antimicrobial use is commonly associated with the development of antimicrobial resistance, monitoring the volume and patterns of use of these agents is very important. To assess the use of macrolide and lincosamide (ML) antimicrobials within Canadian provinces over time, and to compare use rates with those reported by European ...
Baqueiro Cárdenas Erick - - 2014
The queen conch, Strombus gigas, is a gastropod of commercial importance in the Caribbean. Population studies are based on size frequency analysis, using either length or weight parameters for the whole live organism. This contribution used mark-recapture data to estimate the Von Bertalanffy equation parameters and population number variation within ...
Mehta Hiren J - - 2014
An estimated 150,000 pulmonary nodules are identified each year, and the number is likely to increase given the results of the National Lung Screening Trial. Decision tools are needed to help with the management of such pulmonary nodules. We examined whether adding any of three novel functions of nodule volume ...
Ikumi D S DS Water Research Group, Department of Civil Engineering, University of Cape Town, Rondebosch, 7700 Cape, South - - 2014
The investigation provides experimental evidence that the unbiodegradable particulate organics fractions of primary sludge and waste activated sludge calculated from activated sludge models remain essentially unbiodegradable in anaerobic digestion. This was tested by feeding the waste activated sludge (WAS) from three different laboratory activated sludge (AS) systems to three separate ...
Hartnack Sonja S Section of Epidemiology, Vetsuisse Faculty, University of Zurich, Zurich, - - 2014
Method comparison studies are needed for validation of new methods of measurements, for example, non-invasive blood pressure measurements against standard reference methods. After a brief introduction into method comparison studies, this paper is organized in three sections. The first section deals with the widely, though not always appropriately, used classical ...
Chen Zheng Jian ZJ School of Chemical and Biomedical Engineering, Nanyang Technological University , 62 Nanyang Drive, Singapore - - 2014
For 1-alkyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imides and their cationic C2-methylated isomers, that is, [CnMIm]NTf2 and [Cn-1DMIm]NTf2 (n = 3-8), the latter always has much higher viscosities (∼1.66 times at 25 °C) than the former. This finding is unexpected and contrary to the loss of the predominant hydrogen bonding between the cation and anion, ...
Maderbacher Günther G Department of Orthopaedic Surgery, University of Regensburg, Regensburg, Germany, - - 2014
Restoring the joint line (JL) improves clinical and functional outcome in total knee arthroplasty (TKA). Therefore, anatomical landmarks to approximate the JL have been published. So far, the natural deviation of the JL 90° to the mechanical tibial axis has not been considered. Thus, we designed this study to: (1) ...
Kalaszi Adrian - - 2014
3D shape- or volume-based virtual screening is a broadly used approach in drug discovery. In recent years a large number of publications have appeared in which these tools were compared to not only competitive methods but to docking studies as well. Studies often showed that the effectiveness of docking could ...
Schmidt Anne A Department of Pediatrics, University Hospital of Bern, Bern, Switzerland; University Children's Hospital of Basel, Basel, - - 2014
The new ATS/ERS consensus report recommends in vitro validation of multiple-breath inert gas washout (MBW) equipment based on a lung model with simulated physiologic conditions. We aimed to assess accuracy of two MBW setups for infants and young children using this model, and to compare functional residual capacity (FRC) from ...
Sjölander Arvid A Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, - - 2014
The attributable fraction is a widely used measure to quantify the public health impact of an exposure on an outcome. It was originally proposed for binary outcomes, but attributable fraction estimators have also been proposed for time-to-event outcomes. In this note, we consider an estimator which was proposed by Benichou ...
Duignan Timothy Thomas - - 2014
Continuum solvent models of electrolyte solutions are extremely useful. However, before we can use them with confidence, it is important to test them by comparison with a range of experimental properties. Here, we have adapted our recently developed1,2 simple continuum solvent model of ionic solvation free energies to calculate the ...
Lafave Mark R MR Department of Physical Education and Recreation Studies, Mount Royal University, Calgary, AB, - - 2014
Context : Health care professions have replaced traditional multiple-choice tests or essays with structured and practical, performance-based examinations with the hope of eliminating rater bias and measuring clinical competence. Objective : To establish the validity and reliability of the Standardized Orthopedic Assessment Tool (SOAT) as a measure of clinical competence ...
Yang Zhao Z UCB BioSciences, Inc., 8010 Arco Corporate Drive, Raleigh, NC 27617, - - 2014
Kappa statistic is widely used to assess the agreement between two procedures in the independent matched-pair data. For matched-pair data collected in clusters, on the basis of the delta method and sampling techniques, we propose a nonparametric variance estimator for the kappa statistic without within-cluster correlation structure or distributional assumptions. ...
Schmidt P J PJ Department of Statistics and Actuarial Science, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada. Electronic address: - - 2014
Concentrations of particular types of microorganisms are commonly measured in various waters, yet the accuracy and precision of reported microorganism concentration values are often questioned due to the imperfect analytical recovery of quantitative microbiological methods and the considerable variation among fully replicated measurements. The random error in analytical recovery estimates ...
Meshkov Vladimir V VV Department of Chemistry, Lomonosov Moscow State University, Leninskie gory 1/3, 119991 Moscow, - - 2014
We have performed new direct-potential-fit (DPF) analyses of the rotationally resolved [Formula: see text] stimulated emission pumping spectra of Be2 [J. M. Merritt, V. E. Bondybey, and M. C. Heaven, Science 324, 1548 (2009)] using two quite different analytical potential energy functions that incorporate the correct theoretically known long-range behaviour ...
Lu Zhen Z J. Vernon Luck Orthopaedic Research Center, UCLA & Orthopaedic Institute for Children Department of Orthopaedic Surgery, Los Angeles, CA, - - 2014
This study compared the accuracy and sensitivity of several numerical methods employing spherical or plane triangles for calculating the volumetric wear of retrieved metal-on-metal hip joint implants from coordinate measuring machine measurements. Five methods, one using spherical triangles and four using plane triangles to represent the bearing and the best-fit ...
Forget Nancy J NJ School of Physical and Occupational Therapy, McGill University, H3G1Y5 Montreal, Canada. - - 2014
Objective: To report the theoretical foundation of generic patient-reported outcomes for measuring functioning related to upper extremity musculoskeletal disorders and perform content coverage analysis and content comparison using the International Classification of Functioning, Disability and Health (ICF). Methods: A literature search was performed to identify commonly used patient-reported outcomes. A ...
Benjamini Dan D Department of Biomedical Engineering, The Iby and Aladar Fleischman Faculty of Engineering, Tel-Aviv University, Tel-Aviv, 69978, - - 2014
Pore size distribution (PSD) within porous biomaterials is an important microstructural feature for assessing their biocompatibility, longevity, and drug release kinetics. Scanning electron microscopy (SEM) is the most common method to obtain the PSD of soft biomaterials. This method is highly invasive and user dependent, since it requires fracturing of ...
Parsekian A D AD Currently at the Department of Geology and Geophysics, University of Wyoming, 1000 E. University Ave., Laramie, - - 2014
Characterization of hydraulic conductivity (K) in aquifers is critical for evaluation, management, and remediation of groundwater resources. While estimates of K have been traditionally obtained using hydraulic tests over discrete intervals in wells, geophysical measurements are emerging as an alternative way to estimate this parameter. Nuclear magnetic resonance (NMR) logging, ...
Hwang Ji Hye JH 1 Department of Physical Medicine and Rehabilitation, Samsung Medical Center, Center for Clinical Research, Sungkyunkwan University School of Medicine , Seoul, Republic of - - 2014
Abstract Various techniques are available for measuring the status of lymphedema. A modified imaging technique using ultrasonography was developed to measure the structure of soft tissue area in a cost-effective manner. The purpose of this study was to measure the reliability and the accuracy of this new method. Ultrasonography was ...
Wong William W WW USDA/Agricultural Research Service Children's Nutrition Research Center, Baylor College of Medicine, Houston, - - 2014
The doubly labeled water (DLW) method is considered the reference method for the measurement of energy expenditure under free-living conditions. However, the reproducibility of the DLW method in longitudinal studies is not well documented. This study was designed to evaluate the longitudinal reproducibility of the DLW method using 2 protocols ...
Kasarskis Edward J EJ Department of Neurology (EJK), the Graduate Center for Nutrition (EJK), and the Graduate Center for Toxicology (EJK); the Department of Biostatistics, College of Public Health (MSM); the Sanders Brown Center on Aging (MSM and RJK); and the Department of Statistics, College of Arts and Science (RJK), University of Kentucky, Lexington, KY; Neurology Service, Lexington VA Medical Center, Lexington, KY (EJK); the Departments of Chemistry and Medicine (DEM) and Neurology (RT), University of Vermont, Burlington, VT; the Department of Neurology, Columbia University, New York, NY (HM); the Department of Neurology, Pennsylvania State University, Hershey, PA (ZS); and the Department of Neurology, University of Utah, Salt Lake City, UT - - 2014
Patients with amyotrophic lateral sclerosis (ALS) experience progressive limb weakness, muscle atrophy, and dysphagia, making them vulnerable to insufficient energy intake. Methods to estimate energy requirements have not been devised for this patient group. The goal was to develop equations to estimate energy requirements of ALS patients. We enrolled 80 ...
Irrechukwu Onyi N ON National Institute on Aging, National Institutes of Health, Baltimore, MD, - - 2014
Evaluation of mechanical characteristics of cartilage by magnetic resonance imaging would provide a noninvasive measure of tissue quality both for tissue engineering and when monitoring clinical response to therapeutic interventions for cartilage degradation. We use results from multiexponential transverse relaxation analysis to predict equilibrium and dynamic stiffness of control and ...
Sauter M M Division of Gastroenterology and Hepatology, University Hospital Zurich, Zurich, Switzerland; Department of Internal Medicine, Triemli Hospital, Zurich, - - 2014
Measurements of anorectal function using high-resolution anorectal manometry (HR-ARM) and rectal barostat technology provide more reliable results than standard ARM with an elastic balloon; however, HR-ARM results have not been compared to ARM and standard barostat protocols are impractical in routine clinical practice. The aim of this study was to ...
Paim Clésio Soldateli CS Programa de Pós-Graduação em Ciências Farmacêuticas, Universidade Federal do Pampa (UNIPAMPA), Campus Uruguaiana , Uruguaiana - RS , Brasil - - 2014
Abstract Gemifloxacin mesylate (GFM) is a synthetic, broad-spectrum, fluoroquinolone antibacterial agent. It is different from other class members because it achieves adequate plasma concentrations to inhibit both topoisomerase IV and gyrase. The aim of this study was to develop and validate a dissolution test for GFM in coated tablets, using ...
Hwang Jooyeon J a Division of Environmental Health Sciences, School of Public Health , University of Minnesota , MMC 807, 420 Delaware Street SE , Minneapolis , MN , 55455 , - - 2014
ABSTRACT Different dimensions of elongate mineral particles (EMP) have been proposed as being relevant to respiratory health end-points such as mesothelioma and lung cancer. In this article, a methodology for converting personal EMP exposures measured using the NIOSH 7400/7402 methods to exposures based on other size-based definitions has been proposed ...
Schneider Michael D MD Lawrence Livermore National Laboratory, P.O. Box 808 L-210, Livermore, California 94551-0808, USA and University of California, One Shields Avenue, Davis, California 94551, - - 2014
I present an estimator for the angular cross correlation of two tracers of the cosmological large-scale structure that utilizes redshift information to isolate separate physical contributions. The estimator is derived by solving the Limber equation for a reweighting of the foreground tracer that nulls either clustering or lensing contributions to ...
Vannoni Maurizio - - 2014
A method to provide absolute planarity measurements through an interferometric oblique incidence setup and an iterative algorithm is presented. With only three measurements, the calibration of absolute planarity is achieved in a fast and effective manner. Demonstration with synthetic data is provided, and the possible application to very long flat ...
Mulder Emma R ER Image Analysis Center, VU University Medical Center, Amsterdam, The Netherlands; Department of Radiology, VU University Medical Center, Amsterdam, The - - 2014
To measure hippocampal volume change in Alzheimer's disease (AD) or mild cognitive impairment (MCI), expert manual delineation is often used because of its supposed accuracy. It has been suggested that expert outlining yields poorer reproducibility as compared to automated methods, but this has not been investigated. To determine the reproducibilities ...
Cros David D Genetic Improvement and Adaptation of Mediterranean and Tropical Plants Research Unit (AGAP), CIRAD, International campus of Baillarguet, TA A-108/C, 34398, Montpellier Cedex 5, France, - - 2014
Explicit pedigree reconstruction by simulated annealing gave reliable estimates of genealogical coancestry in plant species, especially when selfing rate was lower than 0.6, using a realistic number of markers. Genealogical coancestry information is crucial in plant breeding to estimate genetic parameters and breeding values. The approach of Fernández and Toro ...
Langlois Eric E Centre de Toxicologie du Québec (CTQ), Institut National de Santé Publique du Québec (INSPQ), 945 Ave Wolfe, Québec, Québec G1V 5B3, Canada. Electronic address: - - 2014
Phthalate metabolites are often measured in biomonitoring studies to evaluate a population's exposure to ubiquitous phthalates. During the course of national biomonitoring studies in Canada, we identified an issue with the accuracy of several commercial phthalate metabolite standards that are commonly used in such studies. The validity of the results ...
Munger Crystal C Virginia Commonwealth University, 821 W. Franklin Street Richmond, VA, - - 2014
Refractive indices of seven double-paned vehicle windshields were measured to assess the variation across the pane of glass and to evaluate collection techniques for known glass standards by comparing false negative rates. Measurements were made using a Foster and Freeman GRIM3 instrument, and a minimum of 240 measurements were made ...
Sancho-Bru Joaquin L JL Biomechanics and Ergonomics Group, Department of Mechanical Engineering and Construction, Universitat Jaume I, Castello'n de la Plana, - - 2014
Hand movement measurement is important in clinical, ergonomics and biomechanical fields. Videogrammetric techniques allow the measurement of hand movement without interfering with the natural hand behaviour. However, an accurate measurement of the hand movement requires the use of a high number of markers, which limits its applicability for the clinical ...
Westgate Philip M PM Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, KY 40536, - - 2014
Generalized estimating equations are commonly used to analyze correlated data. Choosing an appropriate working correlation structure for the data is important, as the efficiency of generalized estimating equations depends on how closely this structure approximates the true structure. Therefore, most studies have proposed multiple criteria to select the working correlation ...
Sá Rui Carlos RC 1University of California, San - - 2014
Specific Ventilation Imaging (SVI) uses proton MRI to quantitatively map the distribution of specific ventilation (SV) in the human lung, using inhaled oxygen as a contrast agent. To validate this recent technique, we compared the quantitative measures of heterogeneity of the SV distribution in a 15mm sagittal slice of lung ...
Fonda Borut B a School of Sport, Exercise and Rehabilitation Sciences , University of Birmingham , Birmingham , - - 2014
Abstract The most common bike fitting method to set the seat height is based on the knee angle when the pedal is in its lowest position, i.e. bottom dead centre (BDC). However, there is no consensus on what method should be used to measure the knee angle. Therefore, the first ...
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