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Thomson A J AJ Royal Infirmary of Edinburgh, Edinburgh, - - 2014
Debate continues over the most appropriate blood-brain equilibration rate constant (ke0 ) for use with the Marsh pharmacokinetic model for propofol. We aimed to define the optimal ke0 value. Sixty-four patients were sedated with incremental increases in effect-site target concentration of propofol while using six different ke0 values within the ...
Dryden Ian L IL School of Mathematical Sciences, University of Nottingham, Nottingham, - - 2014
This is a discussion of the paper: 'Overview of object oriented data analysis' by J. Steve Marron and Andrés M. Alonso.
Thomas A M - - 2014
Objective: To compare results from high probability matched sets versus imputed matched sets across differing levels of linkage information. Methods: A series of linkages with varying amounts of available information were performed on two simulated datasets derived from multiyear motor vehicle crash (MVC) and hospital databases, where true matches were ...
Liu Chunling C Department of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong, - - 2014
Clinical trials utilizing predictive biomarkers have become a research focus in personalized medicine. We investigate the effects of biomarker misclassification on the design and analysis of stratified biomarker clinical trials. For a variety of inference problems including marker-treatment interaction in particular, we show that marker misclassification may have profound adverse ...
Neophytou Andreas M AM Department of Environmental Health, Harvard School of Public Health, , Boston, Massachusetts, - - 2014
Occupational cohort studies are often challenged by the Healthy Worker Survivor Effect, which may bias standard methods of analysis. G-estimation of structural failure time models is an approach for reducing this type of bias. Accelerated failure time models have recently been applied in an occupational cohort but cumulative failure time ...
van Duijvenbode Neomi N Behavioural Science Institute, Radboud University Nijmegen , Nijmegen , The Netherlands - - 2014
Abstract Objective: To investigate the reliability and validity of a Wechsler Abbreviated Scale of Intelligence-based Wechsler Adult Intelligence Scale - third edition (WAIS-III) short form (SF) in a sample of individuals with mild to borderline intellectual disability (MBID) (N = 117; MIQ = 71.34; SDIQ = 8.00, range: 52-85). Methods: A full WAIS-III was administered as ...
Andrade Eugenio E Departament of Biology Universidad Nacional de Colombia. Electronic address: - - 2014
I claim that Peirce's notion of information and sign iteration as an intermediation between potentialities that are actualized and actualities that are potentiated provides a suitable framework for interpretation of ZurekĖs Information Gathering and Using Systems (IGUS). Moreover, this model can be extended to address the problem of quantum measurement ...
El-Khorazaty Jill Ann JA Momentum Research, Inc., Durham, NC, - - 2014
In this paper, we describe a method of comparing agreement between two diagnostic contingency tables after adjustment to more clinically relevant marginal distributions using the iterative proportional fitting algorithm. When the categories of a contingency table represent mild, moderate, and severe outcomes, the majority of patients often are in the ...
Banda Jorge A JA Stanford Prevention Research Center, Stanford University, Stanford, - - 2014
To document park use and park and neighborhood environment characteristics in rural communities, and to examine the relationship between park characteristics and park use. The System for Observing Play and Recreation in Communities measured use in 42 target areas across 6 community parks in May 2010 and October 2010. Direct ...
Biehler Martin M Westfälische Wilhelms-Universität Münster, Münster, Germany, - - 2014
Large sample theory states the asymptotic normality of the maximum likelihood estimator of the person parameter in the two parameter logistic (2PL) model. In short tests, however, the assumption of normality can be grossly wrong. As a consequence, intended coverage rates may be exceeded and confidence intervals are revealed to ...
Braverman Julia - - 2014
This study is the first to compare the accuracy of self-reported with actual monetary outcomes of online fixed odds sports betting, live action sports betting, and online casino gambling at the individual level of analysis. Subscribers to bwin.party digital entertainment's online gambling service volunteered to respond to the Brief Bio-Social ...
Rohlfing Curt L CL Department of Pathology & Anatomical Sciences, University of Missouri, Columbia School of Medicine, 1 Hospital Drive, Columbia, MO 65212; Department of Child Health, University of Missouri, Columbia School of Medicine, 1 Hospital Drive, Columbia, MO 65212. Electronic address: - - 2014
Direct comparison of analytical performance criteria that utilize different statistical approaches can be problematic. We describe a mathematical approach to compare performance criteria for hemoglobin A1c (HbA1c) analysis used by the NGSP standardization program and the College of American Pathologists (CAP) to enhance consistency between the schemes. The imprecision (CV) ...
Garibaldi Eduardo E UNICAMP - Department of Mathematics, 13083-859 Campinas - SP, Brazil. Electronic address: - - 2014
This paper considers a two-dimensional logistic model to study populations with two genders. The growth behavior of a population is guided by two coupled ordinary differential equations given by a non-differentiable vector field whose parameters are the secondary sex ratio (the ratio of males to females at time of birth), ...
Pedicini Piernicola P Unit of Nuclear Medicine, Department of Radiation and Metabolic Therapies, I.R.C.C.S.-Regional-Cancer-Hospital-C.R.O.B, 1-Padre-Pio-Street, Rionero-in-Vulture, Italy, - - 2014
The aim of this study was to estimate a radiobiological set of parameters from the available clinical data on glioblastoma (GB). A number of clinical trial outcomes from patients affected by GB and treated with surgery and adjuvant radiochemotherapy were analyzed to estimate a set of radiobiological parameters for a ...
Fitzmaurice Garrett M GM Harvard Medical School, Boston, MA 02115, - - 2014
Relative risks (RRs) are often considered the preferred measures of association in prospective studies, especially when the binary outcome of interest is common. In particular, many researchers regard RRs to be more intuitively interpretable than odds ratios. Although RR regression is a special case of generalized linear models, specifically with ...
Seifert Edward Joseph - - 2014
OriginPro 9.1. OriginLab Corporation, One Roundhouse Plaza, Suite 303, Northampton, MA 01060, United States. 1800-969-7720. www.OriginLab.com. See Web site for pricing information.
Gruber Joshua S - - 2014
Complier average causal effects (CACE) estimate the impact of an intervention among treatment compliers in randomized trials. Methods used to estimate CACE have been outlined for parallel-arm trials (e.g., using an instrumental variables (IV) estimator) but not for other randomized study designs. Here, we propose a method for estimating CACE ...
Hunter Jessica J Department of Human Genetics, Emory University School of Medicine, Atlanta, - - 2014
Prevalence estimates for fragile X syndrome vary considerably. This systematic review and meta-analysis was conducted to provide an accurate prevalence estimate for this disorder using primary publications in PubMed, Embase, and the Cochrane library. Data were pooled using Bayesian fixed-effects and random-effects models. Primary analyses assessed the frequency of the ...
Banerjee Buddhananda B a Applied Statistics Unit , Indian Statistical Institute 203 B. T. Road, Kolkata - 700 108 , - - 2014
Abstract Use of surrogate outcome to improve the inference in biomedical problems is an area of growing interest. Here consider a set up where both the true and surrogate endpoints are binary and we observe all the surrogate endpoints along with a few true endpoints. In a two treatment set ...
Li Hui-Qiong HQ a Department of Statistics , Yunnan University , Kunming 650091 , P. R. - - 2014
Summary Matched-pair design is often used in clinical trials to increase the efficiency of establishing equivalence between two treatments with binary outcomes. In this article, we consider such a design based on rate ratio in the presence of incomplete data. The rate ratio is one of the most frequently used ...
Raj Rahul - - 2014
The aim of this study was to evaluate the usefulness of the APACHE II (Acute Physiology and Chronic Health Evaluation II), SAPS II (Simplified Acute Physiology Score II) and SOFA (Sequential Organ Failure Assessment) scores compared to simpler models based on age and Glasgow Coma Scale (GCS) in predicting long-term ...
Cox Christopher C Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, - - 2014
This paper provides a comparison of the three-parameter exponentiated Weibull (EW) and generalized gamma (GG) distributions. The connection between these two different families is that the hazard functions of both have the four standard shapes (increasing, decreasing, bathtub, and arc shaped), and in fact, the shape of the hazard is ...
Baker Marissa G MG a Department of Environmental and Occupational Health Sciences , University of Washington , Seattle , - - 2014
Despite evidence of adverse health effects resulting from exposure to manganese (Mn), biomarkers of exposure are poorly understood. To enhance understanding, mean blood Mn (MnB) and mean air Mn (MnA) were extracted from 63 exposure groups in 24 published papers, and the relationship was modeled using segmented regression. On a ...
Pieter W W Keimyung University, Daegu, South, - - 2014
Only one study reported the impact attenuation of taekwondo headgear. Although Olympic boxing has discontinued the use of head protectors, similarities in designs are suggested to provide a framework for improving taekwondo helmets as a previous report determined poor testing results. To assess attenuation of taekwondo and boxing headgear. Between-groups. ...
Mc Auliffe S S Clinical Therapies Department, University Of Limerick, Limerick, - - 2014
Pathological tendons are known to increase their AP diameter. Ultrasound is an important complementary technique to MRI for assessment of musculoskeletal disorders. Although systematic reviews have confirmed its reliability for the measurement of muscle thickness, no such reviews exist to examine the reliability of US measures of tendon dimensions. To ...
O'Sullivan D D Chung-Ang University, Anseong, South, - - 2014
To date, only one study reported the impact attenuation of protective taekwondo headgear. Although Olympic boxing has discontinued the use of headgear, similarities in designs are thought to provide a framework for improvements of taekwondo headgear. To determine differences in impact attenuation of taekwondo and boxing headgear. Between groups. Impact ...
Haider Adil H AH From the Center for Surgical Trials and Outcomes Research (A.H.H., Z.G.H., E.R.H., E.B.S., D.T.E.), Department of Surgery, The Johns Hopkins School of Medicine; and Department of Health Policy and Management (A.H.H., E.J.M.), Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland; and Department of Surgery (S.N.Z., E.E.C.), Howard University College of Medicine, Washington, District of - - 2014
The National Trauma Data Bank (NTDB) is an invaluable resource to study trauma outcomes. Recent evidence suggests the existence of great variability in covariate handling and inclusion in multivariable analyses using NTDB, leading to differences in the quality of published studies and potentially in benchmarking trauma centers. Our objectives were ...
Kong Chung Yin CY Institute for Technology Assessment Massachusetts General - - 2014
Background: The incidence of esophageal adenocarcinoma (EAC) has increased five-fold in the United States since 1975. The aim of our study was to estimate future U.S. EAC incidence and mortality and to shed light on the potential drivers in the disease process that are conduits for the dramatic increase in ...
Schneider Gerhard G From the Department of Anesthesiology I, Witten/Herdecke University, Helios Clinic Wuppertal, Wuppertal, Germany (G. Schneider); Department of Anesthesiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany (G. Schneider, D.J., A.O., M.K., and E.F.K.); Department of Anesthesiology and Intensive Care Medicine, Medical University of Graz, Graz, Austria (G. Schwarz); Department of Anesthesiology, Knappschaftskrankenhaus Bochum Langendreer, Klinikum der Ruhr Universität Bochum, Bochum, Germany, and Department of Anesthesiology, University Hospital Hamburg-Eppendorf, Hamburg, Germany (P.B.); Department of Anesthesiology F06-149, University Medical Center Utrecht, GA Utrecht, The Netherlands (C.J.K.); Department of Anesthesiology, German Heart Center Berlin, Berlin, Germany (H.K.); Department of Anesthesiology and Operative Intensive Care, University Hospital Charité, Humboldt-University Berlin, Berlin, Germany (I.R.); Institute of Information Logistics, Department of Computer Science and Applied Cognitive Science, University of Duisburg-Essen, Germany (Hans-Dieter Kochs, Ph.D.) (G. Stockmanns); and Institute of Pattern Recognition, Faculty of Electrical Engineering and Computer Science, University of Applied Sciences Hochschule Niederrhein, Krefeld, Germany (G. - - 2014
For decades, monitoring depth of anesthesia was mainly based on unspecific effects of anesthetics, for example, blood pressure, heart rate, or drug concentrations. Today, electroencephalogram-based monitors promise a more specific assessment of the brain function. To date, most approaches were focused on a "head-to-head" comparison of either electroencephalogram- or standard ...
Sohn Jae-Cheon JC 1 Department of Entomology, University of Maryland, 4112 Plant Sciences Building, College Park, MD 20742, - - 2014
Wockia, one of the six genera within the lepidopteran family Urodidae, currently includes nine species distributed in Holarctic, Oriental, and Neotropical regions. A new species of the genus, W. magna sp. nov., is described from Japan and South Korea. This is the first record of Urodidae from Japan. A cladistic ...
Espinoza Natalisisy N Departamento de Microbiología y Ecología, Facultad de Medicina y Odontología, Universitat de València, Valencia, - - 2014
Chagas disease has historically been hyperendemic in the Bolivian Department of Cochabamba. In the early 2000s, an extensive vector control program was implemented; 1.34 million dwelling inspections were conducted to ascertain infestation (2000-2001/2003-2011), with blanket insecticide spraying in 2003-2005 and subsequent survey-spraying cycles targeting residual infestation foci. Here, we assess ...
Sakai Rie R Department of Social and Behavioral Sciences, Harvard School of Public - - 2014
Objectives: To explore determinants of change in pediatrician supply in Japan, and examine impacts of a 2004 reform of postgraduate medical education on pediatricians' practice location choice.Methods: Data were compiled from secondary data sources. The dependent variable was the change in the number of pediatricians at the municipality ("secondary tier ...
Roudier B B ESIEE Cités Descartes, BP 99, 93162, Noisy Le Grand Cedex, France, - - 2014
In vitro in vivo correlation (IVIVC) is a biopharmaceutical tool recommended for use in formulation development. When validated, IVIVC can be used to set dissolution limits and, based on the dissolution limits, as a surrogate for an in vivo study. The purpose of this paper is to study the various ...
Cao Sissi S Schulich School of Medicine and Dentistry, University of Western Ontario, , London, Ontario, - - 2014
We present three considerations in analysing the association between weight and mortality, as well as other relations that might be non-linear in nature. First, authors must graphically plot their independent and dependent variables in a continuous manner. Second, authors should assess the shape of that relation, and note its shape. ...
Hughes Ra R School of Social and Community Medicine, University of Bristol, Bristol, - - 2014
Appropriate imputation inference requires both an unbiased imputation estimator and an unbiased variance estimator. The commonly used variance estimator, proposed by Rubin, can be biased when the imputation and analysis models are misspecified and/or incompatible. Robins and Wang proposed an alternative approach, which allows for such misspecification and incompatibility, but ...
Catterick David D aDepartment of Economics, City University London, London bHealth Outcomes Department, Sanofi, Guildford, Surrey cKing's College, London and Guy's and St Thomas' NHS Foundation Trust, London, - - 2014
Venous thromboembolism (VTE) is a common and important cause of death in hospital patients. We therefore investigated possible associations between the introduction of the compulsory national VTE risk assessment tool in England in 2010 and patient outcomes. A retrospective database study, using data from the Health and Social Care Information ...
Harland Karisa K KK University of Iowa, College of Public Health, Department of Occupational and Environmental Health, Injury Prevention Research Center, Iowa City, IA, USA; University of Iowa, Department of Emergency Medicine, Iowa City, IA, USA. Electronic address: - - 2014
Although approximately one-third of agricultural equipment-related crashes occur near town, these crashes are thought to be a rural problem. This analysis examines differences between agricultural equipment-related crashes by their urban-rural distribution and distance from a town. Agricultural equipment crashes were collected from nine Midwest Departments of Transportation (2005-2008). Crash zip ...
Wilson Jennifer G JG Department of Emergency Medicine, University of California San Francisco, San Francisco, - - 2014
Ultrasound (US) guidance during central venous catheterization (CVC) reduces complications and improves success rates compared to landmark-guided techniques. A novel "oblique view" (US transducer held at approximately 45° with respect to the target vessel) has been suggested to be superior to the standard short-axis approach usually used during US-guided CVC. ...
Johnson Darren W DW Marine Biology Research Division, Scripps Institution of Oceanography, UC San Diego, La Jolla, CA, 92023, - - 2014
An individual's phenotype will usually influence its probability of survival. However, when evaluating the dynamics of populations, the role of selective mortality is not always clear. Not all mortality is selective, patterns of selective mortality may vary, and it is often unknown how selective mortality compares or interacts with other ...
Higgins H M HM Faculty of Health and Medical Sciences, School of Veterinary Medicine, Guildford, University of Surrey, GU2 7TE, United Kingdom. Electronic address: - - 2014
The clinical beliefs (expectations and demands) of veterinarians regarding herd-level strategies to control mastitis, lameness, and Johne's disease were quantified in a numerical format; 94 veterinarians working in England (UK) were randomly selected and, during interviews, a statistical technique called probabilistic elicitation was used to capture their clinical expectations as ...
Jones Anne A Department of Physiotherapy, James Cook University , Townsville, Queensland , Australia - - 2014
ABSTRACT Objectives: The aim of this study was to assess the concurrent validity and reliability of the Simple Goniometer (SG) iPhone® app compared to the Universal Goniometer (UG). Design: Within subject comparison design comparing the UG with the SG app. Setting: James Cook University, Townsville, Queensland, Australia. Participants: Thirty-six volunteer ...
Lamb Edmund J EJ aClinical Biochemistry bKent Kidney Care Centre, East Kent Hospitals University NHS Foundation Trust, Canterbury, Kent, - - 2014
Glomerular filtration rate (GFR) is the best overall measure of kidney function. Reference GFR measurements (e.g. inulin clearance) are laborious. Estimation of GFR using equations based on endogenous filtration markers is simpler, cheaper and easy to apply in practice but suffers from limited accuracy and reproducibility. This review summarizes the ...
Pinto Paula P Nélio Mendonça Hospital, Funchal, Portugal; School of Medicine, University of Porto, - - 2014
Maternal heart rate (MHR) recordings are morphologically similar and sometimes coincident with fetal heart rate (FHR) recordings and may be useful for maternal-fetal monitoring if appropriately interpreted. However, similarly to FHR, visual interpretation of MHR features may be poorly reproducible. A computer algorithm for on-line MHR analysis was developed based ...
Machado G G Laboratório de Epidemiologia Veterinária (EPILAB), Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, - - 2014
Bovine viral diarrhoea virus (BVDV) causes one of the most important diseases of cattle in terms of economic costs and welfare. The aims were to estimate herd prevalence and to investigate the factors associated with antibodies in bulk tank milk (BTM) in dairy herds through a matched case-control study. To ...
Morfopoulos Catherine C Department of Life Sciences, Imperial College, Silwood Park, Ascot, SL5 7PY, - - 2014
We present a unifying model for isoprene emission by photosynthesizing leaves based on the hypothesis that isoprene biosynthesis depends on a balance between the supply of photosynthetic reducing power and the demands of carbon fixation. We compared the predictions from our model, as well as from two other widely used ...
Fletcher-Watson Sue S Moray House School of Education, University of Edinburgh, St John's Land, Holyrood Road, Edinburgh, UK, EH8 - - 2014
The 'Theory of Mind' (ToM) model suggests that people with autism spectrum disorder (ASD) have a profound difficulty understanding the minds of other people - their emotions, feelings, beliefs, and thoughts. As an explanation for some of the characteristic social and communication behaviours of people with ASD, this model has ...
Kilama Maxwell - - 2014
The Plasmodium falciparum entomological inoculation rate (PfEIR) is a measure of exposure to infectious mosquitoes. It is usually interpreted as the number of P. falciparum infective bites received by an individual during a season or annually (aPfEIR). In an area of perennial transmission, the accuracy, precision and seasonal distribution (i.e., ...
Chong Uven - - 2014
The environmental impact of diesel-fueled buses can potentially be reduced by the adoption of alternative propulsion technologies such as lean-burn compressed natural gas (LB-CNG) or hybrid electric buses (HEB), and emissions control strategies such as a continuously regenerating trap (CRT), exhaust gas recirculation (EGR), or selective catalytic reduction with trap ...
Cuevas Antonio A Departamento de Matemáticas, Universidad Autónoma de Madrid, Madrid, - - 2014
This note is a discussion on the paper "Overview of object oriented data analysis," by J. Steve Marron and Andrés M. Alonso.
Suzuki Edward M EM Washington State Crime Laboratory, Washington State Patrol, 2203 Airport Way South, Building A, Suite 250, Seattle, WA, - - 2014
Bismuth oxychloride (BiOCl) was the first viable synthetic pearl pigment developed 50 years ago. It was only used for a limited time period in automotive paint (model years 1998-2000), serving to produce luster for a single Chrysler black metallic color. Identification of this pigment in an unknown automotive paint can thus ...
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