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Sievers Fabian - - 2014
Guide-trees are used as part of an essential heuristic to enable the calculation of multiple sequencealignments. They have been the focus of much method development but there has been little effortat determining systematically, which guide-trees, if any, give the best alignments. Some guide-treeconstruction schemes are based on pair-wise distances amongst ...
Ishikawa Kazuya K Department of Physics, Faculty of Science, University of Tokyo, Bunkyo-ku, Tokyo 113-0033, - - 2014
We consider a singlino dark matter (DM) scenario in a singlet extension model of the minimal supersymmetric standard model, which is the so-called the nearly minimal supersymmetric standard model. We find that with high-scale supersymmetry breaking the singlino can obtain a sizable radiative correction to the mass, which opens a ...
Bai Z Z Physics Department, Columbia University, New York, New York 10027, - - 2014
We report on the first complete calculation of the K_{L}-K_{S} mass difference, ΔM_{K}, using lattice QCD. The calculation is performed on a 2+1 flavor, domain wall fermion ensemble with a 330 MeV pion mass and a 575 MeV kaon mass. We use a quenched charm quark with a 949 MeV mass to implement ...
Shiozawa Yui Y Department of Physics and Astronomy, Texas Christian University, Fort Worth, Texas 76129, - - 2014
Numerical methods which utilize partitions of equal-size, including the box-counting method, remain the most popular choice for computing the generalized dimension of multifractal sets. However, it is known that mass-oriented methods generate relatively good results for computing generalized dimensions for important cases where the box-counting method is known to fail. ...
Glaister M M School of Human Sciences, St Mary's University, Waldegrave Road, Strawberry Hill, Twickenham, TW1 4SX, UK, - - 2014
The aims of this study were to evaluate the recovery kinetics of peak power output (PPO) following a maximal sprint, and to evaluate the influence of aerobic fitness on that recovery process. On separate occasions, 16 well-trained men (age: 21 ± 3 years; height: 1.84 ± 0.05 m; and body mass: 78.8 ± 7.8 kg) performed a 30 s maximal ...
Carlson Jordan A JA University of California, San Diego, San Diego, - - 2014
To assess validity of the Personal Activity Location Measurement System (PALMS) for deriving time spent walking/running, bicycling, and in vehicle, using SenseCam as the comparison. 40 adult cyclists wore a Qstarz BT-Q1000XT GPS data logger and SenseCam (camera worn around neck capturing multiple images every minute) for a mean of ...
Kuiper Rebecca M RM Department of Methodology and Statistics, Utrecht University, The - - 2014
In this paper, the performance of six types of techniques for comparisons of means is examined. These six emerge from the distinction between the method employed (hypothesis testing, model selection using information criteria, or Bayesian model selection) and the set of hypotheses that is investigated (a classical, exploration-based set of ...
Thomson A J AJ Royal Infirmary of Edinburgh, Edinburgh, - - 2014
We studied the use of a new ke0 value (0.6 min(-1) ) for the Marsh pharmacokinetic model for propofol. Speed of induction and side-effects produced were compared with three other target-controlled infusion systems. Eighty patients of ASA physical status 1-2 were studied in four groups in a prospective, randomised study. Median ...
Arnau Jaime J Universidad de - - 2014
Background: This study examined the independent effect of skewness and kurtosis on the robustness of the linear mixed model (LMM), with the Kenward-Roger (KR) procedure, when group distributions are different, sample sizes are small, and sphericity cannot be assumed. Methods: A Monte Carlo simulation study considering a split-plot design involving ...
Draganov Peter V PV Peter V Draganov, Roxana M Coman, Mihir S Wagh, Division of Gastroenterology, Hepatology and Nutrition, University of Florida, Gainesville, FL 32608, United - - 2014
To evaluate the role of observation of experts performing endoscopic submucosal dissection (ESD) in the acquisition of ESD skills. This prospective study is documenting the learning curve of one Western endoscopist. The study consisted of three periods. In the first period (pre-observation), the trainee performed ESDs in animal models in ...
Kelly M E ME The Adelaide and Meath Hospital -Tallaght, Trinity College Dublin, Dublin, Ireland, - - 2014
The traditional model for emergency surgical care consists of an on-call team providing service to the emergency department, while simultaneously balancing the demands of elective work. Various newer models, such as the "surgeon of the week" aim to reduce the conflict between elective and emergency duties. Despite the recent focus ...
Glen J B JB Research Department, Glen Pharma, Cheshire, - - 2014
We compared the predictive performance of the existing Diprifusor and Schnider models, used for target-controlled infusion of propofol, with a new modification of the Diprifusor model (White) incorporating age and sex covariates. The bias and inaccuracy (precision) of each model were determined using computer simulation to replicate the infusion profiles ...
Young Sharon S CooperRiis Healing Farm, Mill Spring, NC, 28756, - - 2014
This study summarizes the results of a 10 year longitudinal study of individual recovery progress within a residential program based upon therapeutic community principles and a Seven Domains Enhanced Recovery Model that emerged from a grounded theory analysis of real life recovery experiences (Young and Ensing, Psychiatr Rehab J 22:219-231, 1999). ...
Orme Mark - - 2014
It is difficult to compare accelerometer-derived estimates of moderate-to-vigorous physical activity (MVPA) between studies due to differences in data processing procedures. We aimed to evaluate the effects of accelerometer processing options on total and bout-accumulated time spent in MVPA in adults. 267 participants from the ProActive Trial provided 1236 days ...
Hamra Ghassan B GB International Agency for Research on Cancer, , Lyon, - - 2014
Asbestos is a known carcinogen. However, little is known about the differential effects of size-specific asbestos fibres. Previous research has examined the relationship with lung cancer of each fibre group in the absence of others. Attempts to model all fibre groups within a single regression model have failed due to ...
Korner-Nievergelt Fränzi F Swiss Ornithological Institute CH-6204, Sempach, - - 2014
For the study of migratory connectivity, birds have been individually marked by metal rings for more than 100 years. The resulting ring recovery data have been compiled in numerous bird migration atlases. However, estimation of what proportion of a particular population is migrating to which region is confounded by spatial ...
Kuparinen Anna A Department of Environmental Sciences, P.O. Box 65, 00014 University of Helsinki, Finland; Ecological Genetics Research Unit, Department of Biosciences, P.O. Box 65, 00014 University of Helsinki, Finland. - - 2014
Recovery of depleted populations is fundamentally important for conservation biology and sustainable resource harvesting. At low abundance, population growth rate, a primary determinant of population recovery, is generally assumed to be relatively fast because competition is low (i.e., negative density dependence). But population growth can be limited in small populations ...
Hatch Quinton Q Department of Surgery, Madigan Army Medical Center, 9040-A Fitzsimmons Drive, Tacoma, WA 98431, - - 2014
Injury-related coagulopathy is a complex process. We analyzed coagulation in a swine model of shock using rotational thromboelastometry (ROTEM). Forty-eight swine underwent laparotomy, 35% hemorrhage, supraceliac aortic cross-clamp, then reperfusion and resuscitation. ROTEM measurements and standard labs were taken at baseline and 6 hours into resuscitation. Clot formation time (98 vs ...
Gomez J J The University of Manchester, School of Dentistry, Colgate-Palmolive Dental Health Unit, Williams House, Manchester Science Park, Lloyd St North, Manchester, M15 6SE, - - 2014
The aim of this study was to compare the ability of quantitative light-induced fluorescence (QLF) and surface microhardness (SMH) to measure the remineralization of enamel subsurface lesions, using a pH-cycling model including treatment with 0-ppm, 550-ppm or 1,100-ppm sodium fluoride (NaF) dentifrices. Methods: Subsurface lesions were created in human enamel ...
Basheer Hasan Diya'uddeen D Department of Chemical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia ; National Research Institute for Chemical Technology, PMB 1052, Zaria, - - 2014
The mineralisation kinetics of petroleum refinery effluent (PRE) by Fenton oxidation were evaluated. Within the ambit of the experimental data generated, first-order kinetic model (FKM), generalised lumped kinetic model (GLKM), and generalized kinetic model (GKM) were tested. The obtained apparent kinetic rate constants for the initial oxidation step (k 2'), ...
Anastasopoulou Panagiota P House of Competence - hiper.campus, Karlsruhe Institute of Technology, Karlsruhe, - - 2014
The measurement of activity energy expenditure (AEE) via accelerometry is the most commonly used objective method for assessing human daily physical activity and has gained increasing importance in the medical, sports and psychological science research in recent years. The purpose of this study was to determine which of the following ...
Kreuer S S Department of Anaesthesiology, Intensive Care and Pain Therapy, Saarland University Medical Center and Saarland University Faculty of Medicine, 66482 Homburg/Saar; - - 2014
Online measurement of drug concentrations in patient's breath is a promising approach for individualized dosage. A direct transfer from breath- to blood-concentrations is not possible. Measured exhaled concentrations are following the blood-concentration with a delay in non-steady-state situations. Therefore, it is necessary to integrate the breath-concentration into a pharmacological model. ...
Costa Márcia Gisele Santos da MG Centre of Technology Assessment in Health, National Institute of Cardiology, Rio de Janeiro, - - 2014
The study performs a cost-effectiveness analysis of procedures for atrial septal defects occlusion, comparing conventional surgery to septal percutaneous implant. A model of analytical decision was structured with symmetric branches to estimate cost-effectiveness ratio between the procedures. The decision tree model was based on evidences gathered through meta-analysis of literature, ...
Focks Andreas A Aquatic Ecology and Water Quality Management Group, Wageningen University, Wageningen University and Research centre, P Wageningen, The Netherlands; Alterra, Wageningen University and Research centre, Wageningen, The - - 2013
The aim of the conducted work was to assess whether populations effects and recovery times increase when a population of a vulnerable aquatic invertebrate is exposed to concentrations of one or multiple pesticides. The two sets of pesticide combinations are typical for orchard and tuber crops in The Netherlands. Exposure ...
Patel Nishant D ND University of California San Diego Health System, Urology, San Diego, California, United States ; - - 2013
Introduction: Endoscopic treatment of renal calculi relies on surgeon assessment of residual stone fragment size for either basket removal or for the passage of fragments post-operatively. We therefore sought to determine the accuracy of endoscopic assessment of renal calculi size. Materials and Methods: Between January to May 2013, five board ...
Farber Michaela K - - 2013
A 1:1:1 ratio of PRBCs, FFP, and platelets (PLT) has been advocated for trauma hemorrhage, but the effectiveness of this ratio for postpartum hemorrhage (PPH) is unknown. We created an in vitro hemodilutional model to investigate this strategy. Blood from 20 parturients at term was diluted 50% with 0.9% NS. ...
Sherwin M T Catherine - - 2013
Multiple blood samples are generally required for measurement of pharmacokinetic (PK) parameters. D-optimal design is a popular and frequently used approach for determination of sampling time points in order to minimize the number of samples, while optimizing the estimation of PK parameters. Optimal design utilizing ADAPT (v5, BSR, University of ...
Tanha Tina - - 2013
Very few validation studies have been performed between different generations of the commonly used Actigraph accelerometers. We compared daily physical activity data generated from the old generation Actigraph model 7164 with the new generation Actigraph GT1M accelerometer in 15 young females for eight consecutive days. We also investigated if different ...
Wu Chung-Ze CZ Division of Endocrinology and Metabolism Department of Internal Medicine Shuang Ho Hospital Taipei Taiwan ; Graduate Institute of Clinical Medicine College of Medicine Taipei Medical University Taipei - - 2014
How to measure insulin resistance (IR) accurately and conveniently is a critical issue for both clinical practice and research. In the present study, we tried to modify the β-cell function, insulin sensitivity, and glucose tolerance test (BIGTT) in patients with normal glucose tolerance (NGT) and abnormal glucose tolerance (AGT) by ...
Christensen Jay R - - 2013
Within the Southeastern (SE) Coastal Plain of the U.S., numerous freshwaters and estuaries experience eutrophication with significant nutrient contributions by agricultural non-point sources (NPS). Riparian buffers are often used to reduce agricultural NPS yet the effect of buffers in the watershed is difficult to quantify. Using corrected Akaike information criterion ...
Rekić Dinko - - 2013
This work explores the advantages of a model based drug development (MBDD) approach for the design and analysis of antiretroviral phase II trials. Two different study settings were investigated: (1) a 5-arm placebo-controlled parallel group dose-finding/proof of concept (POC) study and (2) a comparison of investigational drug and competitor. Studies ...
Shanks Vicki - - 2013
OBJECTIVE Mental health systems internationally have adopted a goal of supporting recovery. Measurement of the experience of recovery is, therefore, a priority. The aim of this review was to identify and analyze recovery measures in relation to their fit with recovery and their psychometric adequacy. METHODS A systematic search of ...
Hudson Kerry D - - 2013
Drawings by individuals with Williams syndrome (WS) typically lack cohesion. The popular hypothesis is that this is a result of excessive focus on local-level detail at the expense of global configuration. In this study, we explored a novel hypothesis that inadequate attention might underpin drawing in WS. WS and typically ...
Wadhwa Supneet Singh - - 2013
To determine the time dependent accuracy of casts made from three different irreversible hydrocolloids. The effect of delayed pouring on the accuracy of three different irreversible hydrocolloid impression materials - Regular set CA 37(Cavex, The Netherlands), regular set chromatic (Jeltrate, Dentsply), and fast set (Hydrogum soft, Zhermack Clinical) was investigated. ...
Rajiv Sukanya - - 2013
BACKGROUND: Achieving and maintaining haemostasis is of paramount importance in neurosurgery. Chitosan has been shown in both animal and human models to be significantly effective in haemostasis as well as in reducing adhesion formation. OBJECTIVES: To evaluate the haemostatic potential and to study histopathological changes caused by novel chitosan dextran ...
Mailey Emily L - - 2013
The criteria one uses to reduce accelerometer data can profoundly influence the interpretation of research outcomes. The purpose of this study was to examine the influence of three different interruption periods (i.e., 20, 30, and 60 minutes) on the amount of data retained for analyses and estimates of sedentary time ...
Jin Ren-Cun - - 2013
In this study, the recovery performance of two anaerobic ammonium oxidation (ANAMMOX) reactors (R1, R2) that were previously subjected to phenol and sulfide for nearly 200days with respective levels of 12.5-50 and 8-40mgL(-1) and then operated in the absence of these suppressors was investigated. High nitrogen removal rates of greater ...
De Marchi M - - 2013
Recently, a general deterioration of milk coagulation properties (MCP) has been observed in Italy; thus, the prediction of noncoagulating (NC) milk, defined as milk not forming a curd within 30 min from rennet addition, is of immediate interest in the Italian cheese industry. The present study investigated the ability of ...
Caillaud Damien D Section of Integrative Biology, The University of Texas at Austin, 1 University Station, Austin, TX 78712, USA. - - 2013
Contact patterns in group-structured populations determine the course of infectious disease outbreaks. Network-based models have revealed important connections between group-level contact patterns and the dynamics of epidemics, but these models typically ignore heterogeneities in within-group composition. Here, we analyse a flexible mathematical model of disease transmission in a hierarchically structured ...
Powell Mark R - - 2013
A recent paper by Ferrier and Buzby provides a framework for selecting the sample size when testing a lot of beef trim for Escherichia coli O157:H7 that equates the averted costs of recalls and health damages from contaminated meats sold to consumers with the increased costs of testing while allowing ...
Murbach Manuel - - 2013
PURPOSE: This article investigates the safety of radiofrequency induced local thermal hotspots within a 1.5T body coil by assessing the transient local peak temperatures as a function of exposure level and local thermoregulation in four anatomical human models in different Z-positions. METHODS: To quantize the effective thermal stress of the ...
Cao Ran R Key Laboratory of Drug Targeting and Drug Delivery System, Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu 610041, PR - - 2013
Tetramethylpyrazine (TMP) is used to treat cerebrovascular and cardiovascular diseases. However, it displays a short half-life that restricts clinical applications. 2-Hydroxymethyl-3,5,6-trimethylpyrazine (HTMP) is the principal active metabolite of TMP, with similar activity of TMP. Therefore, it makes sense to improve the biopharmaceutical characteristics via HTMP bypassing TMP. To prolong the ...
Russell Mark - - 2013
ABSTRACT: The aim of this study was to investigate the effect of match-play on the performance of technical actions in professional soccer players. Using computerized notational analysis, technical performance was quantified for the outfield players of one team during the 2010/2011 English Championship season. This retrospective study evaluated temporal patterns ...
Bozkurt Hayriye - - 2013
Studies are needed to bridge existing data gaps and determine appropriate parameters for thermal inactivation methods for human noroviruses. Cultivable surrogates, such as feline calicivirus (FCV-F9) and murine norovirus (MNV-1), have been used in the absence of human norovirus infectivity assays. This study aimed to characterize the thermal inactivation kinetics ...
Marom Nimrod - - 2013
The faunal assemblage from the 9(th)-8(th) millennium BP site at Sha'ar Hagolan, Israel, is used to study human interaction with wild suids and cattle in a time period just before the appearance of domesticated animals of these species in the Jordan Valley. Our results, based on demographic and osteometric data, ...
Deli Roberto - - 2013
The objective of this study is to define an acquisition protocol that is clear, precise, repeatable, simple, fast and that is useful for analysis of the anthropometric characteristics of the soft tissue of the face. The analysis was carried out according to a new clinical-instrumental protocol that comprises four distinct ...
Mealer Meredith M Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, United States of - - 2013
Barriers to executing large-scale randomized controlled trials include costs, complexity, and regulatory requirements. We hypothesized that source document verification (SDV) via remote electronic monitoring is feasible. Five hospitals from two NIH sponsored networks provided remote electronic access to study monitors. We evaluated pre-visit remote SDV compared to traditional on-site SDV ...
Rathfon Dana - - 2012
Quantitative assessment of post-disaster housing recovery is critical to enhancing understanding of the process and improving the decisions that shape it. Nevertheless, few comprehensive empirical evaluations of post-disaster housing recovery have been conducted, and no standard measurement methods exist. This paper presents a quantitative assessment of housing recovery in Punta ...
Pinto-Leite C M - - 2012
Empirical studies using visual search methods to investigate spider communities were conducted with different sampling protocols, including a variety of plot sizes, sampling efforts, and diurnal periods for sampling. We sampled 11 plots ranging in size from 5 by 10 m to 5 by 60 m. In each plot, we ...
Fradua Luis - - 2012
Abstract The aims of this study were to examine the 1) individual playing area, 2) length and width of the rectangle encompassing the individual playing area and 3) distance between the goalkeepers and their nearest team-mates during professional soccer matches and compare these to previously reported pitch sizes for small-sided ...
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