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Jiang Xinwei - - 2014
Dimensionality reduction (DR) has been considered as one of the most significant tools for data analysis. One type of DR algorithms is based on latent variable models (LVM). LVM-based models can handle the preimage problem easily. In this paper we propose a new LVM-based DR model, named thin plate spline ...
Gao Yang - - 2014
To take full advantage of hyperspectral information, to avoid data redundancy and to address the curse of dimensionality concern, dimensionality reduction (DR) becomes particularly important to analyze hyperspectral data. Exploring the tensor characteristic of hyperspectral data, a DR algorithm based on class-aware tensor neighborhood graph and patch alignment is proposed ...
White K Geoffrey KG University of Otago, New Zealand. Electronic address: - - 2014
The reinforcement context model for performance in delayed matching-to- sample tasks (White and Brown, 2014) predicts the course of forgetting based on the assumption that rewards for extraneous behavior compete with rewards for accurate matching and increase as a linear function of retention-interval duration. In the differential outcomes effect, greater ...
de la Vega de León Antonio - - 2014
Matched molecular pairs (MMPs) consist of pairs of compounds that are transformed into each other by a substructure exchange. If MMPs are formed by compounds sharing the same biological activity, they encode a potency change. If the potency difference between MMP compounds is very small, the substructure exchange (chemical transformation) ...
Castro Victor M VM Partners Research Computing, Partners HealthCare System, One Constitution Center, Boston, MA 02129. Electronic address: - - 2014
The success of many population studies is determined by proper matching of cases to controls. Some of the confounding and bias that afflict Electronic Health Record (EHR)-based observational studies may be reduced by creating effective methods for finding adequate controls. We implemented a method to match case and control populations ...
Mazrouee Sepideh S Computer Science Department, University of California Los Angeles (UCLA), 3551 Boelter Hall, Los Angeles, CA 90095-1596, - - 2014
Understanding exact structure of an individual's haplotype plays a significant role in various fields of human genetics. Despite tremendous research effort in recent years, fast and accurate haplotype reconstruction remains as an active research topic, mainly owing to the computational challenges involved. Existing haplotype assembly algorithms focus primarily on improving ...
Ali Waqar W Department of Statistics, University of Oxford, Oxford OX1 3TG, UK and Molecular and Computational Biology Program, Department of Biological Sciences, University of Southern California, CA 90089-2910, - - 2014
Biological network comparison software largely relies on the concept of alignment where close matches between the nodes of two or more networks are sought. These node matches are based on sequence similarity and/or interaction patterns. However, because of the incomplete and error-prone datasets currently available, such methods have had limited ...
Cauley Stephen F SF Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA; Department of Radiology, Harvard Medical School, Boston, Massachusetts, - - 2014
MR fingerprinting (MRF) is a technique for quantitative tissue mapping using pseudorandom measurements. To estimate tissue properties such as T1 , T2 , proton density, and B0 , the rapidly acquired data are compared against a large dictionary of Bloch simulations. This matching process can be a very computationally demanding ...
Wu Zhenke Z Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland 21205, - - 2014
We address estimation of intervention effects in experimental designs in which (a) interventions are assigned at the cluster level; (b) clusters are selected to form pairs, matched on observed characteristics; and (c) intervention is assigned to one cluster at random within each pair. One goal of policy interest is to ...
DeGiorgio Michael M Department of Biology, Pennsylvania State University, University Park, Pennsylvania, United States of - - 2014
While much effort has focused on detecting positive and negative directional selection in the human genome, relatively little work has been devoted to balancing selection. This lack of attention is likely due to the paucity of sophisticated methods for identifying sites under balancing selection. Here we develop two composite likelihood ...
Blasco Víctor V IVI Sevilla, Sevilla, - - 2014
To correlate the detection of follicle rupture and the number of uterine contractions per minute with the outcome of IUI and to build a predictive model for the outcome of IUI including these parameters. Retrospective cohort study. Fertility clinic. We analyzed data from 610 women who underwent homologous or donor ...
Lesperance Marielle M Carleton Laboratory for Radiotherapy Physics, Department of Physics, Carleton University, Ottawa, Ontario K1S 5B6, - - 2014
To investigate dosimetry for ocular brachytherapy for a range of eye plaque models containing(103)Pd, (125)I, or (131)Cs seeds with model-based dose calculations. Five representative plaque models are developed based on a literature review and are compared to the standardized COMS plaque, including plaques consisting of a stainless steel backing and ...
Gordon Deborah M DM Department of Biology, Stanford University, Stanford, California, United States of - - 2014
Similar patterns of interaction, such as network motifs and feedback loops, are used in many natural collective processes, probably because they have evolved independently under similar pressures. Here I consider how three environmental constraints may shape the evolution of collective behavior: the patchiness of resources, the operating costs of maintaining ...
Kim Hee-Dong HD School of Electrical Engineering, Korea University, Anam-dong 5-ga, Seongbuk-gu, Seoul 136-701, Republic of - - 2014
The improved resistive switching (RS) performance characteristics of nickel nitride (NiN) films-based crossbar array (CBA) memory resistors-such as reduction in the operating voltages, reset current and current/voltage variations; no initial forming process; and set/reset speeds-are demonstrated using nanopyramid-patterned (NPP) platinum-bottom electrodes. Compared with a conventional CBA sample with flat-bottom electrodes, ...
Takahashi Ayuko A Boston University, Biomedical Engineering, Boston, Massachusetts, United States ; - - 2014
Rationale: Extracellular matrix (ECM) remodeling and tissue rupture are factors contributing to the progression of emphysema. Lung tissue elasticity is governed by the tensile stiffness of fibers and the compressive stiffness of proteoglycans. It is not known how proteoglycan remodeling affects tissue stability and destruction in emphysema. Objectives: To characterize ...
Holzapfel Gerhard A GA Graz University of Technology, Institute of Biomechanics, Kronesgasse 5-I, 8010 Graz, Austria. Electronic address: - - 2014
Vulnerable and stable atherosclerotic plaques are heterogeneous living materials with peculiar mechanical behaviors depending on geometry, composition, loading and boundary conditions. Computational approaches have the potential to characterize the three-dimensional stress/strain distributions in patient-specific diseased arteries of different types and sclerotic morphologies and to estimate the risk of plaque rupture ...
Tang An A Department of Radiology, Centre Hospitalier de l'Université de Montréal (CHUM), Montréal, Québec, Canada; Department of Radiology, Radio-Oncology and Nuclear Medicine, Université de Montréal, Montréal, Québec, Canada; Institute of Biomedical Engineering, Université de Montréal, Montréal, Québec, - - 2014
To identify geometric indices of abdominal aortic aneurysms (AAAs) on computed tomography that are associated with higher risk of rupture. This retrospective case-control, institutional review board-approved study involved 63 cases with ruptured or symptomatic AAA and 94 controls with asymptomatic AAA. Three-dimensional models were generated from computed tomography segmentation and ...
Akyildiz Ali C AC Department of Biomedical Engineering, Thoraxcenter, Erasmus Medical Center, Rotterdam, The - - 2014
Progression and rupture of atherosclerotic plaques in coronary and carotid arteries are the key processes underlying myocardial infarctions and strokes. Biomechanical stress analyses to compute mechanical stresses in a plaque can potentially be used to assess plaque vulnerability. The stress analyses strongly rely on accurate representation of the mechanical properties ...
Chai Chen-Ket CK Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands. Electronic address: - - 2014
Accurate material models and associated parameters of atherosclerotic plaques are crucial for reliable biomechanical plaque prediction models. These biomechanical models have the potential to increase our understanding of plaque progression and failure, possibly improving risk assessment of plaque rupture, which is the main cause of ischaemic strokes and myocardial infarction. ...
Houlié N N 1] Berkeley Seismological Laboratory - University of California [2] ETH, SEG, Zurich, CH [3] ETH, GGL, Zurich, - - 2014
We compute a series of finite-source parameter inversions of the fault rupture of the 2004 Parkfield earthquake based on 1 Hz GPS records only. We confirm that some of the co-seismic slip at shallow depth (<5 km) constrained by InSAR data processing results from early post-seismic deformation. We also show 1) that ...
García Rivero Daniel D Department of Prehistory and Archaeology, University of Seville, Seville, - - 2014
Prehistoric material culture proposed to be symbolic in nature has been the object of considerable archaeological work from diverse theoretical perspectives, yet rarely are methodological tools used to test the interpretations. The lack of testing is often justified by invoking the opinion that the slippery nature of past human symbolism ...
Brożek Jolanta J Department of Zoology, Faculty of Biology and Environmental Protection, University of Silesia, Bankowa Street 9, 40-007 Katowice, - - 2014
THE PRESENT STUDY IS A CLADISTIC ANALYSIS OF MORPHOLOGICAL CHARACTERS FOCUSING ON THE FILE OF THE MANDIBLE, THE APICES OF THE MAXILLAE, THE RUPTURING DEVICE ON THE MAXILLAE, THE INTERNAL STRUCTURES OF THE MOUTHPARTS, AND THE EXTERNAL MORPHOLOGY OF THE LABIAL SEGMENTS AS WELL AS THE DISTRIBUTION OF LABIAL SENSILLA ...
Colombelli S S Department of Physics, University of Naples Federico II, Complesso Universitario Monte S. Angelo, via Cinthia, 80126 Naples, - - 2014
The process of earthquake rupture nucleation and propagation has been investigated through laboratory experiments and theoretical modelling, but a limited number of observations exist at the scale of earthquake fault zones. Distinct models have been proposed, and whether the magnitude can be predicted while the rupture is ongoing represents an ...
Wu Baijian B Department of Engineering Mechanics, Southeast University, Nanjing 210096, - - 2014
Background. Calcification is commonly believed to be associated with cardiovascular disease burden. But whether or not the calcifications have a negative effect on plaque vulnerability is still under debate. Methods and Results. Fatigue rupture analysis and the fatigue life were used to evaluate the rupture risk. An idealized baseline model ...
Zhang Jianhua J College of Computer Science, Zhejiang University of Technology, Hangzhou, Zhejiang, - - 2014
Using deformable models to register medical images can result in problems of initialization of deformable models and robustness and accuracy of matching of inter-subject anatomical variability. To tackle these problems, a novel model is proposed in this paper by compounding local invariant features and global deformable geometry. This model has ...
Zhu Dongqing D Department of Health Sciences Research, Mayo Clinic, 200 First St SW, Rochester, MN 55905 and Department of Computer & Information Sciences, University of Delaware, 101 SMITH HALL, Newark, DE 19716, USA Department of Health Sciences Research, Mayo Clinic, 200 First St SW, Rochester, MN 55905 and Department of Computer & Information Sciences, University of Delaware, 101 SMITH HALL, Newark, DE 19716, - - 2014
This article describes our participation of the Gene Ontology Curation task (GO task) in BioCreative IV where we participated in both subtasks: A) identification of GO evidence sentences (GOESs) for relevant genes in full-text articles and B) prediction of GO terms for relevant genes in full-text articles. For subtask A, ...
Cash Sophie K - - 2013
Abstract Objective To explore the process of rupture resolution in cognitive behaviour therapy (CBT) with two good outcome clients with borderline personality disorder (BPD). Method This study employed task-analytic methods to investigate whether the existing CBT rupture resolution model for depression could be validated. Quantitative analyses identified rupture-repair sequences and ...
Ohayon Jacques - - 2013
Coronary atheroma develop in local sites that are widely variable among patients and are considerably variable in their vulnerability for rupture. This article summarizes studies conducted by our collaborative laboratories on predictive biomechanical modeling of coronary plaques. It aims to give insights into the role of biomechanics in the development ...
Lunn David - - 2013
Meta-analysis is often undertaken in two stages, with each study analysed separately in stage 1 and estimates combined across studies in stage 2. The study-specific estimates are assumed to arise from normal distributions with known variances equal to their corresponding estimates. In contrast, a one-stage analysis estimates all parameters simultaneously. ...
Li Zhi-Yong - - 2013
Rupture of atheromatous plaque is the major cause of stroke or heart attack. Considering that the cardiovascular system is a classic fatigue environment, plaque rupture was treated as a chronic fatigue crack growth process in this study. Fracture mechanics theory was introduced to describe the stress status at the crack ...
McCarter Joanna F - - 2013
Amyloid-β (Aβ) plaque deposition plays a central role in the pathogenesis of Alzheimer's disease (AD). Post-mortem analysis of plaque development in mouse models of AD revealed that plaques are initially small, but then increase in size and become more numerous with age. There is evidence that plaques can grow uniformly ...
Heiland Vincent M - - 2013
A biomechanical stress analysis could help to identify carotid plaques that are vulnerable to rupture, and hence reduce the risk of thrombotic strokes. Mechanical stress predictions critically depend on the plaque's constitutive properties, and the present study introduces a concept to derive viscoelastic parameters through an experimental-numerical approach. Carotid plaques ...
Lee Jung-Eun - - 2013
Animal models of Alzheimer disease (AD) are used to study the mechanisms underlying AD pathogenesis, genetic interactions with genes of interest, and environmental risk factors that cause sporadic AD as well as to test the therapeutic effects of AD drug-candidates on neuropathology and cognitive function. To attain a comparative view ...
Saye Robert I - - 2013
Modeling the physics of foams and foamlike materials, such as soapy froths, fire retardants, and lightweight crash-absorbent structures, presents challenges, because of the vastly different time and space scales involved. By separating and coupling these disparate scales, we have designed a multiscale framework to model dry foam dynamics. This leads ...
Chai Chen-Ket - - 2013
The fibrous cap of an atherosclerotic plaque may be prone to rupture if the occurring stresses exceed the strength of the cap. Rupture can cause acute thrombosis and subsequent ischaemic stroke or myocardial infarction. A reliable prediction of the rupture probability is essential for the appropriate treatment of atherosclerosis. Biomechanical ...
Massip Florian F Max Planck Institute for Molecular Genetics, 14195 Berlin, - - 2013
Recently, an enrichment of identical matching sequences has been found in many eukaryotic genomes. Their length distribution exhibits a power law tail raising the question of what evolutionary mechanism or functional constraints would be able to shape this distribution. Here we introduce a simple and evolutionarily neutral model, which involves ...
Cilla Myriam - - 2013
Rupture of atherosclerotic plaque, which is related to maximal stress conditions in the plaque among others, is a major cause of mortality. More careful examination of stress distributions in atherosclerotic plaques reports that it could be due to local stress behaviors at critical sites caused by cap thinning, inflammation, macroscopic ...
Martufi Giampaolo - - 2013
AAA disease is a serious condition and a multidisciplinary approach including biomechanics is needed to better understand and more effectively treat this disease. A rupture risk assessment is central to the management of AAA patients, and biomechanical simulation is a powerful tool to assist clinical decisions. Central to such a ...
Kume Naoto - - 2013
Virtual reality (VR) simulation is expected to be advantageous to surgical training for invasive operations such as incision and dissection that are unrepeatable in the real world. This study focuses on ablation in order to provide a simulation model for soft tissue rupture progression. To simulate soft tissue handling by ...
Craig Jean B JB Office of Biomedical Informatics Services, Medical University of South Carolina, Charleston, South - - 2013
To describe the methods of evaluating currently available triage models for their efficacy in appropriately triaging the surge of patients after an all-hazards disaster. A method was developed for evaluating currently available triage models using extracted data from medical records of the victims from the Graniteville chlorine disaster. On January ...
Forsell Caroline - - 2012
Assessing the risk for abdominal aortic aneurysm (AAA) rupture is critical in the management of aneurysm patients and an individual assessment is possible with the biomechanical rupture risk assessment. Such an assessment could potentially be improved by a constitutive AAA wall model that accounts for irreversible damage-related deformations. Because of ...
Safenkova I V - - 2012
Atomic force microscopy (AFM) can be used to make measurements in vacuum, air, and water. The method is able to gather information about intermolecular interaction forces at the level of single molecules. This review encompasses experimental and theoretical data on the characterization of ligand-receptor interactions by AFM. The advantage of ...
Campbell Ian C IC Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta, Georgia 30322, - - 2013
Spontaneous plaque rupture in mouse models of atherosclerosis is controversial, although numerous studies have discussed so-called "vulnerable plaque" phenotypes in mice. We compared the morphology and biomechanics of two acute and one chronic murine model of atherosclerosis to human coronaries of the thin-cap fibroatheroma (TCFA) phenotype. Our acute models were ...
Viswanathan T - - 2012
This paper investigated the effect of cell rupturing methods on the drying characteristics and the lipid compositions of a green algae consortium grown in an open raceway pond. The ruptured microalgae samples obtained from French press, autoclave and sonication methods were used for conducting thin layer drying experiment at four ...
Watkins C Edward CE - - 2012
What role does the real relationship play in psychoanalytic supervision? While the real relationship's role has long been and continues to be considered with regard to psychoanalysis, it has received virtually no attention in the supervision literature. In this paper, using Horney's construct of the real self as conceptual anchor, ...
Jo Junghyo - - 2012
The islets of Langerhans, ranging in size from clusters of a few cells to several thousand cells, are scattered near large blood vessels. While the beta-cell mass in mammals is proportional to body weight, the size ranges of islets are similar between species with different body sizes, possibly reflecting an ...
Afonso David D Institute for Systems and Robotics, IST, Lisbon, Portugal. - - 2012
Recently, several atherosclerotic plaque characterization methods were proposed based on plaque morphology assessed through 2D ultrasound. It is of extreme importance to establish an objective quantification measure which allows the physicians to determine the risk of plaque rupture, and thus, of brain stroke. Having these, sometimes complex, measures easily and ...
Bakker Arnold B - - 2011
Abstract This study among 267 Greek teachers and their partners tested and expanded the recently proposed Spillover-Crossover model (SCM) of well-being. Accordingly, experiences built up at work spill over to the home domain, and then influence the partner. The authors integrated equity theory in the model by formulating hypotheses about ...
Sazonova Nadezhda - - 2011
: The aim of this study was to develop and validate a method for predicting energy expenditure (EE) using a footwear-based system with integrated accelerometer and pressure sensors. : We developed a footwear-based device with an embedded accelerometer and insole pressure sensors for the prediction of EE. The data from ...
Desmarais Sarah L - - 2011
Surveys typically characterize lay knowledge of eyewitness factors as low and highly variable. However, there are notable differences across methodologies, samples, and individual factors. To examine these differences systematically, we took a meta-analytic approach to reviewing the findings of 23 surveys assessing lay knowledge of eyewitness issues. Our analyses examined ...
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