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Popescu Vasilica V "Gheorghe Asachi" Technical University, Faculty of Textiles, Leather Engineering and Industrial Management, 29 Blvd. Mangeron, TEX 1 Building, Iasi 700050, Romania. Electronic address: - - 2014
Realization of simultaneous hydrophilizing and wrinkle-proofing effects on a cotton fabric is not impossible. This work proves that these objectives can be reached by using adequate multifunctional compounds: Tetronic 701 (T), chitosan (CS) and monochlorotriazine-β-cyclodextrin (MCT-β-CD). These were applied by means of three pad-dry-cure type treatments. We have studied, at ...
Caluwaerts Ken K Dynamic Tensegrity Robotics Lab, NASA Ames Research Center, Moffett Field, CA, USA Reservoir Lab, Department of Electronics and Information Systems, Ghent University, Ghent, Belgium - - 2014
To better understand the role of tensegrity structures in biological systems and their application to robotics, the Dynamic Tensegrity Robotics Lab at NASA Ames Research Center, Moffett Field, CA, USA, has developed and validated two software environments for the analysis, simulation and design of tensegrity robots. These tools, along with ...
Armbruster W Scott WS School of Biological Sciences, University of Portsmouth, Portsmouth PO12DY, UK Institute of Arctic Biology, University of Alaska, Fairbanks, AK 99775, USA Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway - - 2014
Integration and modularity refer to the patterns and processes of trait interaction and independence. Both terms have complex histories with respect to both conceptualization and quantification, resulting in a plethora of integration indices in use. We review briefly the divergent definitions, uses and measures of integration and modularity and make ...
Bisetti Fabrizio F Clean Combustion Research Center, King Abdullah University of Science and Technology, Thuwal 23955, Kingdom of Saudi Arabia - - 2014
Combustion of fossil fuels is likely to continue for the near future due to the growing trends in energy consumption worldwide. The increase in efficiency and the reduction of pollutant emissions from combustion devices are pivotal to achieving meaningful levels of carbon abatement as part of the ongoing climate change ...
Giles M B MB Mathematical Institute, University of Oxford, Oxford, UK - - 2014
High-performance computing has evolved remarkably over the past 20 years, and that progress is likely to continue. However, in recent years, this progress has been achieved through greatly increased hardware complexity with the rise of multicore and manycore processors, and this is affecting the ability of application developers to achieve ...
Slotnick Jeffrey P JP Flight Sciences, The Boeing Company, Huntington Beach, CA, USA - - 2014
As global air travel expands rapidly to meet demand generated by economic growth, it is essential to continue to improve the efficiency of air transportation to reduce its carbon emissions and address concerns about climate change. Future transports must be 'cleaner' and designed to include technologies that will continue to ...
Fletcher Thomas T School of Earth and Environment, University of Leeds, Leeds, West Yorkshire LS2 9JT, UK - - 2014
From their earliest origins, fishes have developed a suite of adaptations for locomotion in water, which determine performance and ultimately fitness. Even without data from behaviour, soft tissue and extant relatives, it is possible to infer a wealth of palaeobiological and palaeoecological information. As in extant species, aspects of gross ...
Mahadevan Vijay S VS Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, IL 60439, USA - - 2014
An integrated multi-physics simulation capability for the design and analysis of current and future nuclear reactor models is being investigated, to tightly couple neutron transport and thermal-hydraulics physics under the SHARP framework. Over several years, high-fidelity, validated mono-physics solvers with proven scalability on petascale architectures have been developed independently. Based ...
van Elteren Arjen A Leiden Observatory, Leiden University, PO Box 9513, 2300 RA Leiden, The Netherlands - - 2014
Astronomical phenomena are governed by processes on all spatial and temporal scales, ranging from days to the age of the Universe (13.8 Gyr) as well as from kilometre size up to the size of the Universe. This enormous range in scales is contrived, but as long as there is a physical ...
Hoekstra Alfons A Computational Science, Institute for Informatics, Faculty of Science, University of Amsterdam, The Netherlands National Research University ITMO, St Petersburg, Russian Federation - - 2014
We argue that, despite the fact that the field of multiscale modelling and simulation has enjoyed significant success within the past decade, it still holds many open questions that are deemed important but so far have barely been explored. We believe that this is at least in part due to ...
Bennike S S Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark; Copenhagen Centre for Team Sport and Health, Copenhagen, - - 2014
This article explores a new Danish football-based activity for health called Football Fitness (FF). Data are from quantitative and qualitative methods, and the theoretical framework for the analysis of the organizational form of FF is the theory of path dependency (Mahoney) and first- and second-order change (Watzlawick et al.). Theories of ...
Peccora Christian D CD Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, - - 2014
Measuring and providing performance feedback to physicians has gained momentum not only as a way to comply with regulatory requirements, but also as a way to improve patient care. Measurement of structural, process, and outcome metrics in a reliable, evidence-based, specialty-specific manner maximizes the probability of improving physician performance. The ...
Mangel Marc M Center for Stock Assessment Research and Department of Applied Mathematics and Statistics, University of California, Santa Cruz, CA, USA, - - 2014
I describe how stochastic dynamic programming (SDP), a method for stochastic optimization that evolved from the work of Hamilton and Jacobi on variational problems, allows us to connect the physiological state of organisms, the environment in which they live, and how evolution by natural selection acts on trade-offs that all ...
Xu Siyan S a Boston University , Biostatistics , 801 Massachusetts Avenue, Boston MA - - 2014
Non-inferiority (NI) clinical trials are getting a lot of attention of late due to its direct application in biosimilar studies. Because of missing placebo arm, NI is an indirect approach to demonstrate efficacy of a test treatment. One of the key assumptions on the NI test is constancy assumption, that ...
Liu Qing Q a Experimental & Analytical Science, AbacusCloud, LLC , P. O.Box 236, Long Valley , NJ - - 2014
Abstract Clinical trials are mostly designed to provide data that allow direct inference of the underlying hypotheses. This, however, is not the case for non-inferiority trials where placebo controls are absent due to ethical considerations, resulting in the need for indirect inference about the underlying hypotheses of the treatment effect ...
Nagasaki Masayuki M a Biostatistics Group, Center for Product Evaluation, Pharmaceuticals and Medical Devices Agency , - - 2014
Abstract In recent years, development of biosimilar products has attracted considerable attention. Because of the structural complexity of biologics, it is difficult to demonstrate that a biosimilar product is identical to the reference product. Therefore, for the development of biosimilar products, we need to adopt an approach that is different ...
Abrahamyan Lusine L Toronto Health Economics and Technology Assessment Collaborative, University of Toronto, Toronto, Ontario, - - 2014
Hemophilia A is a rare, sex-linked genetic disorder treated with intravenous administration of factor VIII (FVIII) to prevent bleeding; however, approaches vary across and within countries. Value-of-information (VOI) methods identify situations in which the cost-benefit evidence is sufficient to adopt one treatment strategy over another; when the evidence is insufficient, ...
Foster Charles - - 2014
Property-based models of the ownership of body parts are common. They are inadequate. They fail to deal satisfactorily with many important problems, and even when they do work, they rely on ideas that have to be derived from deeper, usually unacknowledged principles. This article proposes that the parent principle is ...
Huang Yangxin Y Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL, USA yhuang@health.usf.edu - - 2014
It is a common practice to analyze longitudinal data frequently arisen in medical studies using various mixed-effects models in the literature. However, the following issues may standout in longitudinal data analysis: (i) In clinical practice, the profile of each subject's response from a longitudinal study may follow a "broken stick" ...
Tappenden Paul P Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, UK, - - 2014
Health economic models have become the primary vehicle for undertaking economic evaluation and are used in various healthcare jurisdictions across the world to inform decisions about the use of new and existing health technologies. Models are required because a single source of evidence, such as a randomised controlled trial, is ...
Duarte Fernanda F Science for Life Laboratory, Department of Cell and Molecular Biology (ICM), Uppsala University, BMC Box 596, S-751 24 Uppsala, - - 2014
Recent years have seen enormous progress in the development of methods for modeling (bio)molecular systems. This has allowed for the simulation of ever larger and more complex systems. However, as such complexity increases, the requirements needed for these models to be accurate and physically meaningful become more and more difficult ...
Jankowski Tomasz T Institute of Psychology, The John Paul II Catholic University of Lublin, Al. Racławickie 14, 20-950 Lublin, Poland. Electronic address: - - 2014
Mindfulness training has proven to be an efficacious therapeutic tool for a variety of clinical and nonclinical health problems and a booster of well-being. In this paper we propose a multi-level metacognitive model of mindfulness. We postulate and discuss following hypothesis: (1) mindfulness is related to the highest level of ...
Richter Franziska F Institute of Pharmacology, Pharmacy and Toxicology, Department of Veterinary Medicine, University of Leipzig, 04103 Leipzig, - - 2014
Animal models are pivotal for studies of pathogenesis and treatment of disorders of the central nervous system which in its complexity cannot yet be modeled in vitro or using computer simulations. The choice of a specific model to test novel therapeutic strategies for a human disease should be based on ...
Deng Xinyang X School of Computer and Information Science, Southwest University, Chongqing, 400715, - - 2014
As an equilibrium refinement of the Nash equilibrium, evolutionarily stable strategy (ESS) is a key concept in evolutionary game theory and has attracted growing interest. An ESS can be either a pure strategy or a mixed strategy. Even though the randomness is allowed in mixed strategy, the selection probability of ...
van der Harst Eugenie E Environmental Systems Analysis Group, Wageningen University, Droevendaalsesteeg 3, P.O. Box 47, NL-6700 AA Wageningen, The Netherlands. Electronic address: - - 2014
This study used multiple data sets and modelling choices in an environmental life cycle assessment (LCA) to compare typical disposable beverage cups made from polystyrene (PS), polylactic acid (PLA; bioplastic) and paper lined with bioplastic (biopaper). Incineration and recycling were considered as waste processing options, and for the PLA and ...
Erev Ido I Industrial Engineering and Management, Technion, Haifa 32000, Israel;Warwick Business School, The University of Warwick, Coventry CV4 7AL, United Kingdom; and alroth@stanford.edu - - 2014
The rationality assumption that underlies mainstream economic theory has proved to be a useful approximation, despite the fact that systematic violations to its predictions can be found. That is, the assumption of rational behavior is useful in understanding the ways in which many successful economic institutions function, although it is ...
Chai C C a Centre for Infrastructure Systems, School of Civil and Environmental Engineering , Nanyang Technological University , 50 Nanyang Avenue, - - 2014
ABSTRACT Objective This study applies a simulation technique to evaluate the hypothesis that red-light cameras (RLCs) exert important effects on accident risks. Conflict occurrences are generated by simulation and compared at intersections with and without RLCs to assess the impact of RLCs on several conflict types under various traffic conditions. ...
Carsetti Arturo A La Nuova Critica, Rome, Italy, - - 2014
At the biological level, what is innate is the result of an evolutionary process and is "programed" by natural selection. Natural selection is the "coder" (once linked to the emergence of meaning). This coupled process is indissolubly correlated with the continuous construction of new formats in accordance with the unfolding ...
Cox Christopher E CE Duke University, Medicine , Box 102043 , Durham, North Carolina, United States , 27710 , 919-681-7232 , 919-681-8359 ; - - 2014
In the setting of a complex critical illness, preference-sensitive decision making-choosing between two or more reasonable treatment options-can be difficult for patients, families, and clinicians alike. A common challenge to making high-quality decisions in this setting is a lack of critical information access and sharing among participants. Decision aids-brochures, web ...
Lomnitz Jason G - - 2014
Considerable progress has been made in identifying and characterizing the component parts of genetic oscillators, which play central roles in all organisms. Nonlinear interaction among components is sufficiently complex that mathematical models are required to elucidate their elusive integrated behavior. Although natural and synthetic oscillators exhibit common architectures, there are ...
Kandori Michihiro M Faculty of Economics, The University of Tokyo, Tokyo 113-0033, Japan; and - - 2014
Humans are capable of cooperating with one another even when it is costly and a deviation provides an immediate gain. An important reason is that cooperation is reciprocated or rewarded and deviations are penalized in later stages. For cooperation to be sustainable, not only must rewards and penalties be strong ...
Sacchi Emanuele E The University of British Columbia, Department of Civil Engineering, 2002, 6250 Applied Science Lane, Vancouver, B.C., Canada V6T 1Z4. Electronic address: - - 2014
Collision modification factors (CMFs) are commonly used to quantify the impact of safety countermeasures. The CMFs obtained from observational before-after (BA) studies are usually estimated by averaging the safety impact (i.e., index of effectiveness) for a group of treatment sites. The heterogeneity among the treatment locations, in terms of their ...
Czaczkes Tomer J TJ Biologie I, Universität Regensburg, 93040 Regensburg, Germany. Electronic address: - - 2014
Ant foraging is an important model system in the study of adaptive complex systems. Many ants use trail pheromones to recruit nestmates to resources. Differential recruitment depending on resource quality coupled with positive feedback allows ant colonies to make rapid and accurate collective decisions about how best to allocate their ...
Smolen Paul P Laboratory of Origin: Department of Neurobiology and Anatomy, W. M. Keck Center for the Neurobiology of Learning and Memory, The University of Texas Medical School at Houston, Houston, Texas 77030, United States of America. Electronic address: - - 2014
Congenital cognitive dysfunctions are frequently due to deficits in molecular pathways that underlie the induction or maintenance of synaptic plasticity. For example, Rubinstein-Taybi syndrome (RTS) is due to a mutation in cbp, encoding the histone acetyltransferase CREB-binding protein (CBP). CBP is a transcriptional co-activator for CREB, and induction of CREB-dependent ...
Marsh Kevin K Evidera, Metro Building, 6th Floor, 1 Butterwick, W6 8DL, London, UK, - - 2014
Assessing the economic value of treatments for chronic lymphocytic leukaemia (CLL) is necessary to support healthcare decision makers; however, it poses a number of challenges. This paper reviews economic models of CLL treatment to learn the lessons from this experience and support ongoing model efforts. A search of databases and ...
Carvalho-Pereira Ticiana Soares de Andrade de TS Biology Institute - Federal University of Bahia (UFBA), Campus de Ondina, 40170-115 Salvador, Bahia, Brazil. Electronic address: - - 2014
Cultivation medium is one of the first aspects to be considered in zooplankton laboratory cultivation. The use of artificial media does not concern to reproduce natural conditions to the cultivations, which may be achieved by using natural organic compounds like humic substances (HS). This study aimed to evaluate the effects ...
Einstein S - - 2014
This point-of-view commentary explores a selected range of issues relevant to alcoholic beverage drinking and nondrinking patterns documented by the AMPHORA European study which, with hind-sight, limits its generalizability, with fore-sight are generally inadequately considered and documented and, with ordinary insight, are not likely to affect the ongoing and future ...
Diaby Vakaramoko V Division of Economic, Social and Administrative Pharmacy, College of Pharmacy and Pharmaceutical Sciences, Florida A&M University (FAMU), Tallahassee, FL, USA, - - 2014
Everolimus in combination with exemestane significantly improved progression-free survival compared to exemestane alone in patients previously treated with non-steroidal aromatase inhibitors in the BOLERO-2 trial. As a result, this combination has been approved by the food and drug administration to treat postmenopausal women with hormone receptor positive and HER2 negative ...
Rhodes William W Abt Associates Inc., Cambridge, MA, USA - - 2014
Cluster randomization (CR) is often used for program evaluation when simple random assignment is inappropriate or infeasible. Pairwise cluster random (PCR) assignment is a more efficient alternative, but evaluators seemed to be deterred from PCR because of bias and identification problems. This article explains the problems, argues that they can ...
Galvagne Loss Ana Teresa - - 2014
Studies on popular names of birds help to understand the relationship between human beings and birds and it also contributes to the field of ornithology. This study aims to register the ethnotaxonomy of birds in the village of Pedra Branca, Santa Teresinha municipality, Bahia State, Brazil, by cataloguing and identifying ...
Manju Md Abu - - 2014
In this paper, the optimal sample sizes at the cluster and person levels for each of two treatment arms are obtained for cluster randomized trials where the cost-effectiveness of treatments on a continuous scale is studied. The optimal sample sizes maximize the efficiency or power for a given budget or ...
Guidi Gabriele - - 2014
In this paper we present a Clinical Decision Support System (CDSS) for the analysis of Heart Failure (HF) patients, providing various outputs such as an HF severity evaluation, HF type prediction, as well as a management interface that compares the different patient's follow-ups. The whole system is composed of a ...
Akay Altug - - 2014
Intelligently extracting knowledge from social media has recently attracted great interest from the Biomedical and Health Informatics community to simultaneously improve healthcare outcomes and reduce costs using consumergenerated opinion. We propose a two-step analysis framework that focuses on positive and negative sentiment, as well as the side effects of treatment, ...
Agarwal Gunjan G Microsystems Technology Laboratories (MTL), Massachusetts Institute of Technology, Cambridge, MA 02139, USA. - - 2014
Precise, size-selective assembly and sorting are demonstrated in a low-cost system using manufacturable, replicated polymer templates to guide the assembly. Surface interactions between microscale objects and an assembly template are combined with fluid forces to drive site-selective organization of objects onto the template. Although controlling the organization of deformable objects ...
Heller Ruth R Department of Statistics and Operations Research, Tel-Aviv University, Tel-Aviv 6997801, Israel - - 2014
Identification of SNPs that are associated with a phenotype in more than one study is of great scientific interest in GWAS research. The empirical Bayes approach for discovering whether results have been replicated across studies was shown to be a reliable method, and close to optimal in terms of power. ...
Suki Béla B Department of Biomedical Engineering, Boston University, Boston, MA, - - 2014
Emphysema is a progressive disease characterized by deterioration of alveolar structure and decline in lung function. While morphometric and molecular biology studies have not fully uncovered the underlying mechanisms, they have produced data to advance computational modeling. In this review, we discuss examples in which modeling has led to novel ...
Zhang Bijun B Department of Life Science Informatics, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry, Rheinische Friedrich-Wilhelms-Universität, Dahlmannstr. 2, 53113, Bonn, - - 2014
Activity landscapes (ALs) of compound data sets are rationalized as graphical representations that integrate similarity and potency relationships between active compounds. ALs enable the visualization of structure-activity relationship (SAR) information and are thus computational tools of interest for medicinal chemistry. For AL generation, similarity and potency relationships are typically evaluated ...
Rafferty Anna N AN Computer Science Division , University of California , Berkeley, CA 94720, - - 2014
Computer games can be motivating and engaging experiences that facilitate learning, leading to their increasing use in education and behavioural experiments. For these applications, it is often important to make inferences about the knowledge and cognitive processes of players based on their behaviour. However, designing games that provide useful behavioural ...
Kertzscher G G 1 Centre for Nuclear Technologies, Technical University of Denmark, Roskilde, - - 2014
The error types during brachytherapy (BT) treatments and their occurrence rates are not well known. The limited knowledge is partly attributed to the lack of independent verification systems of the treatment progression in the clinical workflow routine. Within the field of in vivo dosimetry (IVD), it is established that real-time ...
Liu Zhun-Ga - - 2014
The classification of incomplete patterns is a very challenging task because the object (incomplete pattern) with different possible estimations of missing values may yield distinct classification results. The uncertainty (ambiguity) of classification is mainly caused by the lack of information of the missing data. A new prototype-based credal classification (PCC) ...
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