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Joksić Agnes Šömen AŠ a National Institute of Public Health , Koper , Republic of - - 2014
In spite of the ease with which samples may be collected and the stability of the samples after collection, the use of hair mineral analysis for monitoring environmental exposures and evaluating heavy metal poisonings has remained controversial since its initial applications for these purposes in the early 1950s. Among the ...
Popescu Vasilica V "Gheorghe Asachi" Technical University, Faculty of Textiles, Leather Engineering and Industrial Management, 29 Blvd. Mangeron, TEX 1 Building, Iasi 700050, Romania. Electronic address: - - 2014
Realization of simultaneous hydrophilizing and wrinkle-proofing effects on a cotton fabric is not impossible. This work proves that these objectives can be reached by using adequate multifunctional compounds: Tetronic 701 (T), chitosan (CS) and monochlorotriazine-β-cyclodextrin (MCT-β-CD). These were applied by means of three pad-dry-cure type treatments. We have studied, at ...
Puckett James G JG Department of Mechanical Engineering and Materials Science, Yale University, New Haven, CT 06520, - - 2014
Social animals commonly form aggregates that exhibit emergent collective behaviour, with group dynamics that are distinct from the behaviour of individuals. Simple models can qualitatively reproduce such behaviour, but only with large numbers of individuals. But how rapidly do the collective properties of animal aggregations in nature emerge with group ...
Zhang Jing J State Key Laboratory of Pollution Control and Resource Reuse, Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, PR China; College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing, Zhejiang 314001, PR - - 2014
The threshold model based on monotonic concentration-response curves (CRCs) is unsuitable to assess the risk of chemicals with non-monotonic CRCs. The non-monotonic CRCs of mixtures may relate to the characteristics of some individual component. To reveal the cause of the mixtures resulting in the non-monotonic CRCs, we used the microplate ...
Kendon Adam A Institute for Research in Cognitive Science, University of Pennsylvania, Philadelphia, PA 19104-6228, USA Division of Psychology and Language Sciences, University College London, London, WC1H 0AP, UK - - 2014
Sign language descriptions that use an analytic model borrowed from spoken language structural linguistics have proved to be not fully appropriate. Pictorial and action-like modes of expression are integral to how signed utterances are constructed and to how they work. However, observation shows that speakers likewise use kinesic and vocal ...
Hartmann William K WK Planetary Science Institute, 1700 East Fort Lowell Road, Suite 106, Tucson, AZ 85719-2395, USA - - 2014
At the request of editors, this paper offers a historical review of early work on the giant impact hypothesis, as well as comments on new data. The author hereby claims (whether believable or not) that his interest is to move towards a correct model of lunar origin, not to defend ...
Melosh H J HJ Earth, Atmospheric and Planetary Sciences, Purdue University, West Lafayette, IN 47907, USA Physics and Astronomy, Purdue University, West Lafayette, IN 47907, USA Aeronautical and Astronautical Engineering Departments, Purdue University, West Lafayette, IN 47907, USA - - 2014
Recent comparisons of the isotopic compositions of the Earth and the Moon show that, unlike nearly every other body known in the Solar System, our satellite's isotopic ratios are nearly identical to the Earth's for nearly every isotopic system. The Moon's chemical make-up, however, differs from the Earth's in its ...
Caluwaerts Ken K Dynamic Tensegrity Robotics Lab, NASA Ames Research Center, Moffett Field, CA, USA Reservoir Lab, Department of Electronics and Information Systems, Ghent University, Ghent, Belgium - - 2014
To better understand the role of tensegrity structures in biological systems and their application to robotics, the Dynamic Tensegrity Robotics Lab at NASA Ames Research Center, Moffett Field, CA, USA, has developed and validated two software environments for the analysis, simulation and design of tensegrity robots. These tools, along with ...
Yang Guang G Department of Statistics and Biostatistics, Rutgers University, Piscataway, NJ 08854, - - 2014
Network meta-analysis synthesizes several studies of multiple treatment comparisons to simultaneously provide inference for all treatments in the network. It can often strengthen inference on pairwise comparisons by borrowing evidence from other comparisons in the network. Current network meta-analysis approaches are derived from either conventional pairwise meta-analysis or hierarchical Bayesian ...
Barnes Sean L SL Robert H. Smith School of Business, University of Maryland, College Park, - - 2014
Objective. Hand hygiene and environmental cleaning are essential infection prevention strategies, but the relative impact of each is unknown. This information is important in assessing resource allocation. Methods. We developed an agent-based model of patient-to-patient transmission-via the hands of transiently colonized healthcare workers and incompletely terminally cleaned rooms-in a 20-patient intensive care ...
Venrooij Joost - - 2014
Biodynamic feedthrough (BDFT) is a complex phenomenon, that has been studied for several decades. However, there is little consensus on how to approach the BDFT problem in terms of definitions, nomenclature, and mathematical descriptions. In this paper, the framework for BDFT analysis, as presented in Part I of this dual ...
Syed Omaer O Division of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, 256 Grays Inn Road, London WC1X - - 2014
Small intestine submucosa (SIS) has emerged as one of a number of naturally-derived extracellular matrix (ECM) biomaterials currently in clinical use. In addition to clinical applications ECM materials form the basis for a variety of approaches within tissue engineering research. In our preliminary work it was found that SIS can ...
Ohm Lotta - - 2014
Abstract Imatinib has revolutionized the treatment of chronic myeloid leukaemia (CML). We evaluated clinical outcome and cost-effectiveness, using Swedish registry data based on CML-patients diagnosed 1973-2008. Outcome from three time periods (I: 1973-1979; II: 1991-1997; III: 2002-2008) associated with symptomatic treatment, interferon-alpha/stem cell transplantation and implementation of imatinib, respectively, were ...
Evers Silvia M A A SM a Caphri School of Public Health and Primary Care, Department of Health Services Research , Maastricht University , The - - 2014
Abstract Objective: The objectives of this article are first to give an overview of the risks of bias in trial-based economic evaluations and, second, to identify how key sources for bias can be revealed and overcome (i.e. what bias-reducing strategies might be employed) in future trial-based economic evaluations in the ...
Verkerke Hans P HP Division of Infectious Diseases and International Health, University of Virginia, Charlottesville, 22901, - - 2014
Robust detection of enteric protozoa is a critical step toward determining the etiology of diarrhea. Widespread use of conventional microscopy, culturing and antigen detection in both industrial and developing countries is limited by relatively low sensitivity and specificity. Refinements of these conventional approaches that reduce turnaround time and instrumentation have ...
Armbruster W Scott WS School of Biological Sciences, University of Portsmouth, Portsmouth PO12DY, UK Institute of Arctic Biology, University of Alaska, Fairbanks, AK 99775, USA Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway - - 2014
Integration and modularity refer to the patterns and processes of trait interaction and independence. Both terms have complex histories with respect to both conceptualization and quantification, resulting in a plethora of integration indices in use. We review briefly the divergent definitions, uses and measures of integration and modularity and make ...
Cavagnaro Joy J 1 Access BIO , Boyce, - - 2014
This white paper summarizes the current consensus of the Reproductive Subcommittee of the Oligonucleotide Safety Working Group on strategies to assess potential reproductive and/or developmental toxicities of therapeutic oligonucleotides (ONs). The unique product characteristics of ONs require considerations when planning developmental and reproductive toxicology studies, including (a) chemical characteristics, (b) ...
Zhu Zhikai - - 2014
Glycoproteins are biologically significant large molecules that participate in numerous cellular activities. In order to obtain site-specific protein glycosylation information, intact glycopeptides, with the glycan attached to the peptide sequence, are characterized by tandem mass spectrometry (MS/MS) methods such as collision-induced dissociation (CID) and electron transfer dissociation (ETD). While several ...
Linke Thomas T MedImmune, Department of Purification Process Sciences, One MedImmune Way, Gaithersburg, MD, - - 2014
We describe the development and scale-up of a novel two chain immunotoxin refolding process. This work provides a case study comparing a clinical manufacturing process and the commercial process developed to replace it. While the clinical process produced high quality material, it suffered from low yield and high yield variability. ...
Zhao Shanshan S Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, - - 2014
Mediation analysis is important for understanding the mechanisms whereby one variable causes changes in another. Measurement error could obscure the ability of the potential mediator to explain such changes. This article focuses on developing correction methods for measurement error in the mediator with failure time outcomes. We consider a broad ...
Levi Carmit Shani CS Laboratory of Chemistry of Foods and Bioactives, Department of Biotechnology and Food Engineering, Technion - Israel Institute of Technology, Haifa 32000, Israel. - - 2014
The world's population is inevitably ageing thanks to modern progress; however, the development of food and oral formulations tailored to the needs of the elderly is still in its infancy. In vitro digestion models offer high throughput, robust and practically ethics free evaluation of the digestive fate of ingested products. ...
Archibald Mandy M MM Doctoral candidate, Faculty of Nursing, Edmonton Clinic Health Academy, University of Alberta, Edmonton, Alberta, - - 2014
Arts-based approaches to knowledge translation are emerging as powerful interprofessional strategies with potential to facilitate evidence uptake, communication, knowledge, attitude, and behavior change across healthcare provider and consumer groups. These strategies are in the early stages of development. To date, no classification system for arts-based knowledge translation exists, which limits ...
Lok U-Wai UW National Taiwan - - 2014
The powerful parallel computation ability of a graphics processing unit (GPU) makes it feasible to perform dynamic receive beamforming However, a real time GPU-based beamformer requires high data rate to transfer radio-frequency (RF) data from hardware to software memory, as well as from central processing unit (CPU) to GPU memory. ...
Gürcan Onder O Computer Engineering Department, Ege University, Universite Cad., 35100, Bornova, Izmir, Turkey, - - 2014
Correct knowledge of the effective connectivity at the synaptic level in humans is a key prerequisite for increasing our understanding of the operation of the human central nervous system. Unfortunately, none of the current ambitious collaborative neuroscience projects pay enough attention to this topic and are thus unable to completely ...
LaKind Judy S JS LaKind Associates, LLC 106 Oakdale Avenue, Catonsville, MD 21228, USA; Department of Epidemiology and Public Health, University of Maryland School of Medicine, USA; Department of Pediatrics, Penn State University College of Medicine, Milton S. Hershey Medical Center, USA. Electronic address: - - 2014
The quality of exposure assessment is a major determinant of the overall quality of any environmental epidemiology study. The use of biomonitoring as a tool for assessing exposure to ubiquitous chemicals with short physiologic half-lives began relatively recently. These chemicals present several challenges, including their presence in analytical laboratories and ...
Bouchet Phil J PJ The UWA Oceans Institute, School of Animal Biology, The University of Western Australia, Crawley, Western Australia, 6009, - - 2014
Despite being identified as a driver of mobile predator aggregations (hotspots) in both marine and terrestrial environments, topographic complexity has long remained a challenging concept for scientists to visualise and a difficult parameter to estimate. It is only with the advent of high-speed computers and the recent popularisation of geographical ...
Forsman Jukka T - - 2014
BackgroundSocial information use is usually considered to lead to ecological convergence among involved con- or heterospecific individuals. However, recent results demonstrate that observers can also actively avoid behaving as those individuals being observed, leading to ecological divergence. This phenomenon has been little explored so far, yet it can have significant ...
Billari Francesco C FC Department of Sociology and Nuffield College, University of Oxford, Oxford, UK, - - 2014
This article suggests a procedure to derive stochastic population forecasts adopting an expert-based approach. As in previous work by Billari et al. (2012), experts are required to provide evaluations, in the form of conditional and unconditional scenarios, on summary indicators of the demographic components determining the population evolution: that is, ...
Zhang Ying - - 2014
Infectious disease surveillance is a process the product of which reflects both actual disease trends and public awareness of the disease. Decisions made by patients, health care providers, and public health professionals about seeking and providing health care and about reporting cases to health authorities are all influenced by information ...
Schweiger Dominik - - 2014
Semantic Web has established itself as a framework for using and sharing data across applications and database boundaries. Here, we present a web-based platform for querying biological Semantic Web databases in a graphical way. SPARQLGraph offers an intuitive drag & drop query builder, which converts the visual graph into a ...
Babst Flurin F Laboratory of Tree-Ring Research, University of Arizona, 1215 E Lowell St, Tucson, AZ, 85721, USA, - - 2014
Tree-ring records can provide valuable information to advance our understanding of contemporary terrestrial carbon cycling and to reconstruct key metrics in the decades preceding monitoring data. The growing use of tree rings in carbon-cycle research is being facilitated by increasing recognition of reciprocal benefits among research communities. Yet, basic questions ...
Kong Y Y a State Key Laboratory of Chemical Resource Engineering, Department of Pharmaceutical Engineering , Beijing University of Chemical Technology , Beijing , - - 2014
In this study, four computational quantitative structure-activity relationship (QSAR) models were built to predict the bioactivity of 3' processing (3'P) inhibitors of HIV-1 integrase. Some 453 inhibitors whose bioactivity values were detected by the radiolabelling method were collected. The molecular structures were represented with MOE descriptors. In total, 21 descriptors ...
Bullot Nicolas J NJ Department of Cognitive Science, ARC Centre of Excellence in Cognition and its Disorders, Macquarie - - 2014
To introduce the issue of the tracking and identification of human agents, I examine the ability of an agent ("a tracker") to track a human person ("a target") and distinguish this target from other individuals: The ability to perform person identification. First, I discuss influential mechanistic models of the perceptual ...
Tatem Andrew J AJ Department of Geography and Environment, University of Southampton, UK Fogarty International Center, National Institutes of Health, Bethesda, USA Flowminder Foundation, Stockholm, Sweden - - 2014
Measuring progress towards international health goals requires a reliable baseline from which to measure change and recent methodological advancements have advanced our abilities to measure, model and map the prevalence of health issues using sophisticated tools. The provision of burden estimates generally requires linking these estimates with spatial demographic data, ...
Huang Ying Y Fred Hutchinson Cancer Research Center, Public Health Sciences, 1100 Fairview Avenue N., Seattle, Washington 98109-1024, U.S.A.; Department of Biostatistics, University of Washington, Seattle, Washington 98195, - - 2014
Treatment-selection markers predict an individual's response to different therapies, thus allowing for the selection of a therapy with the best predicted outcome. A good marker-based treatment-selection rule can significantly impact public health through the reduction of the disease burden in a cost-effective manner. Our goal in this article is to ...
Cereto-Massagué Adrià A Group of Cheminformatics & Nutrition. Biochemistry and Biotechnology Department, Universitat Rovira i Virgili (URV), Campus de Sescelades, N4 Building, 43007 Tarragona, Catalonia, - - 2014
Molecular fingerprints have been used for a long time now in drug discovery and virtual screening. Their ease of use (requiring little to no configuration) and the speed at which substructure and similarity searches can be performed with them -paired with a virtual screening performance similar to other more complex ...
Brunckhorst Oliver O MRC Centre for Transplantation, King's College London, King's Health Partners, London, United Kingdom; Department of Urology, Guy's and St. Thomas' NHS Foundation Trust, King's Health Partners, London, United - - 2014
Simulation is a common adjunct to operative training and various modalities exist for ureteroscopy. This systematic review aims the following: (1) to identify available ureteroscopy simulators, (2) to explore evidence for their effectiveness using characteristic criterion, and (3) to provide recommendations for simulation-based ureteroscopy training. The preferred reporting items for ...
Gao Wei-Feng - - 2014
Inspired by the fact that in modern society, team cooperation and the division of labor play important roles in accomplishing a task, this paper proposes a dual-population differential evolution (DPDE) with coevolution for constrained optimization problems (COPs). The COP is treated as a bi-objective optimization problem where the first objective ...
Gao Qing - - 2014
This paper investigates the problems of universal fuzzy model and universal fuzzy controller for discrete-time nonaffine nonlinear systems (NNSs). It is shown that a kind of generalized T-S fuzzy model is the universal fuzzy model for discrete-time NNSs satisfying a sufficient condition. The results on universal fuzzy controllers are presented ...
Bisetti Fabrizio F Clean Combustion Research Center, King Abdullah University of Science and Technology, Thuwal 23955, Kingdom of Saudi Arabia - - 2014
Combustion of fossil fuels is likely to continue for the near future due to the growing trends in energy consumption worldwide. The increase in efficiency and the reduction of pollutant emissions from combustion devices are pivotal to achieving meaningful levels of carbon abatement as part of the ongoing climate change ...
Giles M B MB Mathematical Institute, University of Oxford, Oxford, UK - - 2014
High-performance computing has evolved remarkably over the past 20 years, and that progress is likely to continue. However, in recent years, this progress has been achieved through greatly increased hardware complexity with the rise of multicore and manycore processors, and this is affecting the ability of application developers to achieve ...
Paton James Y JY Department of Paediatric Respiratory Medicine, Royal Hospital for Sick Children, Glasgow, - - 2014
The use of data to challenge and improve healthcare has a long and distinguished history but has often failed to bring about expected improvements. It has never become fully embedded in clinical practice, probably because data alone are insufficient to drive change. There is now a greater appreciation that changing ...
May Thomas T Medical College of Wisconsin, Milwaukee, WI, USA, - - 2014
This paper argues that it will be important for new genomic technologies to recognize the limits of traditional approaches to informed consent, so that other-regarding implications of genomic information can be properly contextualized and individual rights respected. Respect for individual autonomy will increasingly require dynamic consideration of the interrelated dimensions ...
Slotnick Jeffrey P JP Flight Sciences, The Boeing Company, Huntington Beach, CA, USA - - 2014
As global air travel expands rapidly to meet demand generated by economic growth, it is essential to continue to improve the efficiency of air transportation to reduce its carbon emissions and address concerns about climate change. Future transports must be 'cleaner' and designed to include technologies that will continue to ...
Peck Mika Robert MR School of Life Sciences, JMS Building, University of Sussex, Falmer, Brighton, BN1 9QJ, United Kingdom. - - 2014
In species-rich tropical forests, effective biodiversity management demands measures of progress, yet budgetary limitations typically constrain capacity of decision makers to assess response of biological communities to habitat change. One approach is to identify ecological-disturbance indicator species (EDIS) whose monitoring is also monetarily cost-effective. These species can be identified by ...
Wong Shen Yuong - - 2014
This paper presents a fuzzy extreme learning machine (F-ELM) that embeds fuzzy membership functions and rules into the hidden layer of extreme learning machine (ELM). Similar to the concept of ELM that employed the random initialization technique, three parameters of F-ELM are randomly assigned. They are the standard deviation of ...
Luo Chuan - - 2014
Two-mode stochastic local search (SLS) and focused random walk (FRW) are the two most influential paradigms of SLS algorithms for the propositional satisfiability (SAT) problem. Recently, an interesting idea called configuration checking (CC) was proposed to handle the cycling problem in SLS. The CC idea has been successfully used to ...
Bolhuis Henk H Department of Marine Microbiology, Royal Netherlands Institute for Sea Research, NIOZ, Korringaweg 7, NL 4401 NT, - - 2014
Phototrophic microbial mats are ideal model systems for ecological and evolutionary analysis of highly diverse microbial communities. Microbial mats are small-scale, nearly closed, self-sustaining benthic ecosystems that comprise the major element cycles, trophic levels and food webs. The steep and fluctuating physicochemical micro-gradients, that are the result of the ever ...
Patrick Christopher J CJ Department of Psychology, Florida State University, Tallahassee, FL - - 2014
The Triarchic model (Patrick, Fowles, & Krueger, 2009) was formulated to reconcile contrasting conceptions of psychopathy reflected in historic writings and contemporary assessment instruments, and to address persisting unresolved issues in the field. The model conceives of psychopathy as encompassing three distinct but interrelated phenotypic dispositions-disinhibition, boldness, and meanness-with biological ...
Jian Weiyan W Department of Health Policy and Management, School of Public Health, Health Science Center, Peking University, Beijing, - - 2014
Diagnosis-related group (DRG) system is a classification system widely used in health managements, the foundation of which lies in the medical information system. A large effort had been made to improve the quality of discharge data before the introduction of DRGs in Beijing. We extract discharge data from 108 local ...
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