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Popescu Vasilica V "Gheorghe Asachi" Technical University, Faculty of Textiles, Leather Engineering and Industrial Management, 29 Blvd. Mangeron, TEX 1 Building, Iasi 700050, Romania. Electronic address: - - 2014
Realization of simultaneous hydrophilizing and wrinkle-proofing effects on a cotton fabric is not impossible. This work proves that these objectives can be reached by using adequate multifunctional compounds: Tetronic 701 (T), chitosan (CS) and monochlorotriazine-β-cyclodextrin (MCT-β-CD). These were applied by means of three pad-dry-cure type treatments. We have studied, at ...
Zhang Jing J State Key Laboratory of Pollution Control and Resource Reuse, Key Laboratory of Yangtze River Water Environment, Ministry of Education, College of Environmental Science and Engineering, Tongji University, Shanghai 200092, PR China; College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing, Zhejiang 314001, PR - - 2014
The threshold model based on monotonic concentration-response curves (CRCs) is unsuitable to assess the risk of chemicals with non-monotonic CRCs. The non-monotonic CRCs of mixtures may relate to the characteristics of some individual component. To reveal the cause of the mixtures resulting in the non-monotonic CRCs, we used the microplate ...
Caluwaerts Ken K Dynamic Tensegrity Robotics Lab, NASA Ames Research Center, Moffett Field, CA, USA Reservoir Lab, Department of Electronics and Information Systems, Ghent University, Ghent, Belgium - - 2014
To better understand the role of tensegrity structures in biological systems and their application to robotics, the Dynamic Tensegrity Robotics Lab at NASA Ames Research Center, Moffett Field, CA, USA, has developed and validated two software environments for the analysis, simulation and design of tensegrity robots. These tools, along with ...
Armbruster W Scott WS School of Biological Sciences, University of Portsmouth, Portsmouth PO12DY, UK Institute of Arctic Biology, University of Alaska, Fairbanks, AK 99775, USA Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway - - 2014
Integration and modularity refer to the patterns and processes of trait interaction and independence. Both terms have complex histories with respect to both conceptualization and quantification, resulting in a plethora of integration indices in use. We review briefly the divergent definitions, uses and measures of integration and modularity and make ...
Bisetti Fabrizio F Clean Combustion Research Center, King Abdullah University of Science and Technology, Thuwal 23955, Kingdom of Saudi Arabia - - 2014
Combustion of fossil fuels is likely to continue for the near future due to the growing trends in energy consumption worldwide. The increase in efficiency and the reduction of pollutant emissions from combustion devices are pivotal to achieving meaningful levels of carbon abatement as part of the ongoing climate change ...
Giles M B MB Mathematical Institute, University of Oxford, Oxford, UK - - 2014
High-performance computing has evolved remarkably over the past 20 years, and that progress is likely to continue. However, in recent years, this progress has been achieved through greatly increased hardware complexity with the rise of multicore and manycore processors, and this is affecting the ability of application developers to achieve ...
Slotnick Jeffrey P JP Flight Sciences, The Boeing Company, Huntington Beach, CA, USA - - 2014
As global air travel expands rapidly to meet demand generated by economic growth, it is essential to continue to improve the efficiency of air transportation to reduce its carbon emissions and address concerns about climate change. Future transports must be 'cleaner' and designed to include technologies that will continue to ...
Fletcher Thomas T School of Earth and Environment, University of Leeds, Leeds, West Yorkshire LS2 9JT, UK - - 2014
From their earliest origins, fishes have developed a suite of adaptations for locomotion in water, which determine performance and ultimately fitness. Even without data from behaviour, soft tissue and extant relatives, it is possible to infer a wealth of palaeobiological and palaeoecological information. As in extant species, aspects of gross ...
Mahadevan Vijay S VS Argonne National Laboratory, 9700 S. Cass Avenue, Argonne, IL 60439, USA - - 2014
An integrated multi-physics simulation capability for the design and analysis of current and future nuclear reactor models is being investigated, to tightly couple neutron transport and thermal-hydraulics physics under the SHARP framework. Over several years, high-fidelity, validated mono-physics solvers with proven scalability on petascale architectures have been developed independently. Based ...
van Elteren Arjen A Leiden Observatory, Leiden University, PO Box 9513, 2300 RA Leiden, The Netherlands - - 2014
Astronomical phenomena are governed by processes on all spatial and temporal scales, ranging from days to the age of the Universe (13.8 Gyr) as well as from kilometre size up to the size of the Universe. This enormous range in scales is contrived, but as long as there is a physical ...
Hoekstra Alfons A Computational Science, Institute for Informatics, Faculty of Science, University of Amsterdam, The Netherlands National Research University ITMO, St Petersburg, Russian Federation - - 2014
We argue that, despite the fact that the field of multiscale modelling and simulation has enjoyed significant success within the past decade, it still holds many open questions that are deemed important but so far have barely been explored. We believe that this is at least in part due to ...
Bennike S S Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark; Copenhagen Centre for Team Sport and Health, Copenhagen, - - 2014
This article explores a new Danish football-based activity for health called Football Fitness (FF). Data are from quantitative and qualitative methods, and the theoretical framework for the analysis of the organizational form of FF is the theory of path dependency (Mahoney) and first- and second-order change (Watzlawick et al.). Theories of ...
Meade Michelle A MA Department of Physical Medicine and Rehabilitation, University of Michigan School of Medicine , Ann Arbor, MI , USA - - 2014
Abstract Purpose: This article provides a conceptual framework for understanding healthcare disparities experienced by individuals with disabilities. While health disparities are the result of factors deeply rooted in culture, life style, socioeconomic status, and accessibility of resources, healthcare disparities are a subset of health disparities that reflect differences in access ...
Schmidt Henning H Advanced Quantitative Sciences, Novartis Pharma AG, Postfach, 4002, Basel, Switzerland, - - 2014
Population pharmacokinetic (popPK) analyses are at the core of Pharmacometrics and need to be performed regularly. Although these analyses are relatively standard, a large variability can be observed in both the time (efficiency) and the way they are performed (quality). Main reasons for this variability include the level of experience ...
Waltham Nathan J NJ Gold Coast City Council, GCMC, PO Box 5042, Gold Coast, QLD, 9729, Australia, - - 2014
The Gold Coast City is the tourist center of Australia and has undergone rapid and massive urban expansion over the past few decades. The Broadwater estuary, in the heart of the City, not only offers an array of ecosystems services for many important aquatic wildlife species, but also supports the ...
Blob Richard W RW *Department of Biological Sciences, Clemson University, 132 Long Hall, Clemson, SC 29634, USA; Department of Biology, University of California Riverside, 900 University Avenue, Riverside, CA 92521, USA - - 2014
Locomotion is fundamental to the survival of many animal species, and terrestrial environments are one of the primary habitats through which a wide range of animals (including humans) must move. Many recent efforts have been made to broaden the approaches and systems used to understand how terrestrial locomotion is executed ...
Compernolle T T Hasselt University, Centre for Environmental Sciences, Agoralaan, Building D, B-3590 Diepenbeek, Belgium. Electronic address: - - 2014
Many studies on technology adoption demonstrate that uncertainty leads to a postponement of investments by integrating a wait option in the economic analysis. The aim of this study however is to demonstrate how the investment in new technologies can be stimulated by integrating an option to abandon. Furthermore, this real ...
Kitsche Andreas A Institut für Biostatistik, Leibniz Universität Hannover, Herrenhäuser Straße 2, Hannover, - - 2014
This study considers the detection of treatment-by-subset interactions in a stratified, randomised clinical trial with a binary-response variable. The focus lies on the detection of qualitative interactions. In addition, the presented method is useful more generally, as it can assess the inconsistency of the treatment effects among strata by using ...
Rosen Michael A MA The Armstrong Institute for Patient Safety and Quality, Baltimore, Maryland, USA Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, - - 2014
There is a strong link between teamwork and patient safety. Emerging evidence supports the efficacy of teamwork improvement interventions. However, the availability of reliable, valid, and practical measurement tools and strategies is commonly cited as a barrier to long-term sustainment and spread of these teamwork interventions. This article describes the ...
Perogamvros Lampros L Department of Psychiatry, Geneva University Hospitals, and Department of Neuroscience, University of Geneva, Geneva, - - 2014
Philosophers, psychiatrists and neuroscientists have all expressed interest in and formulated hypotheses on the nature of hallucinations, but no sufficient integration of these models exists to this date. The objective of this article is to present a neurophilosophical model of psychosis linking the neurobiology with the phenomenology of hallucinations and ...
Janamian Tina T Centre of Research Excellence in Primary Health Care Microsystems, University of Queensland, Brisbane, QLD, Australia. - - 2014
Objective: To review the available literature to identify the major challenges and barriers to implementation and adoption of the patient-centred medical home (PCMH) model, topical in current Australian primary care reforms. Study design: Systematic review of peer-reviewed literature. Data sources: PubMed and Embase databases were searched in December 2012 for ...
Batalha Natalie M NM National Aeronautics and Space Administration Ames Research Center, Moffett Field, 94035 CA - - 2014
The Kepler Mission is exploring the diversity of planets and planetary systems. Its legacy will be a catalog of discoveries sufficient for computing planet occurrence rates as a function of size, orbital period, star type, and insolation flux. The mission has made significant progress toward achieving that goal. Over 3,500 ...
Brummel-Ziedins Kathleen E KE Department of Biochemistry, Colchester Research Facility, University of Vermont, Colchester, Vermont, - - 2014
There exists an imbalance between our understanding of the physiology of the blood coagulation process and the translation of this understanding into useful assays for clinical application. As technology advances, the capabilities for merging the two areas have become more attainable. Global assays have advanced our understanding of the dynamics ...
Lahoz-Beneytez Julio J Bayer Technology Services GmbH, Computational Systems Biology, Leverkusen, 51368, Germany. Electronic address: - - 2014
Biological systems are complex and comprehend multiple scales of organization. Hence, holistic approaches are necessary to capture the behaviour of these entities from the molecular and cellular to the whole organism level. This also applies to the understanding and treatment of different diseases. Traditional systems biology has been successful in ...
Belciug Smaranda S Department of Computer Science, University of Craiova, Craiova 200585, Romania. Electronic address: - - 2014
Automated medical diagnosis models are now ubiquitous, and research for developing new ones is constantly growing. They play an important role in medical decision-making, helping physicians to provide a fast and accurate diagnosis. Due to their adaptive learning and nonlinear mapping properties, the artificial neural networks are widely used to ...
Iansavichus Arthur V AV Kidney Clinical Research Unit, London Health Sciences Centre, London, Ontario, - - 2014
Finding relevant articles in large bibliographic databases such as PubMed, Ovid MEDLINE, and EMBASE to inform care and future research is challenging. Articles relevant to chronic kidney disease (CKD) are particularly difficult to find because they are often published under different terminology and are found across a wide range of ...
Peccora Christian D CD Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, - - 2014
Measuring and providing performance feedback to physicians has gained momentum not only as a way to comply with regulatory requirements, but also as a way to improve patient care. Measurement of structural, process, and outcome metrics in a reliable, evidence-based, specialty-specific manner maximizes the probability of improving physician performance. The ...
Razafimandimbison Sylvain G SG The Bergius Foundation at The Royal Swedish Academy of Sciences and Department of Ecology, Environment and Plant Sciences, Stockholm University, SE-106 91 Stockholm, - - 2014
• Premise of the study: The pantropical, species-rich Psychotrieae and Palicoureeae are sister tribes of mostly drupe-bearing and nonbacterial leaf-nodulating species with problematic generic limits. This problem is more complicated in Psychotrieae due to the paraphyly of the genus Psychotria, the lack of diagnostic characters for some major lineages, and ...
Horvath Monica M MM Duke Health Technology Solutions, Duke University Health System, Durham, NC. Electronic address: - - 2014
Data generated in the care of patients are widely used to support clinical research and quality improvement, which has hastened the development of self-service query tools. User interface design for such tools, execution of query activity, and underlying application architecture have not been widely reported, and existing tools reflect a ...
Ghosh Bapan B Department of Mathematics, Indian Institute of Engineering Science and Technology, Shibpur (Formerly Bengal Engineering and Science University, Shibpur), Howrah-711103, West Bengal, India. Electronic address: - - 2014
We give answers to two important problems arising in current fisheries: (i) how maximum sustainable yield (MSY) policy is influenced by the initial population level, and (ii) how harvesting, oscillation and MSY are related to each other in prey-predator systems. To examine the impact of initial population on exploitation, we ...
Astrup Thomas Fruergaard TF Technical University of Denmark, Department of Environmental Engineering, Miljoevej, Building 113, 2800 Kgs. Lyngby, Denmark. Electronic address: - - 2014
Life cycle assessment (LCA) has been used extensively within the recent decade to evaluate the environmental performance of thermal Waste-to-Energy (WtE) technologies: incineration, co-combustion, pyrolysis and gasification. A critical review was carried out involving 250 individual case-studies published in 136 peer-reviewed journal articles within 1995 and 2013. The studies were ...
Mangel Marc M Center for Stock Assessment Research and Department of Applied Mathematics and Statistics, University of California, Santa Cruz, CA, USA, - - 2014
I describe how stochastic dynamic programming (SDP), a method for stochastic optimization that evolved from the work of Hamilton and Jacobi on variational problems, allows us to connect the physiological state of organisms, the environment in which they live, and how evolution by natural selection acts on trade-offs that all ...
Xu Siyan S a Boston University , Biostatistics , 801 Massachusetts Avenue, Boston MA - - 2014
Non-inferiority (NI) clinical trials are getting a lot of attention of late due to its direct application in biosimilar studies. Because of missing placebo arm, NI is an indirect approach to demonstrate efficacy of a test treatment. One of the key assumptions on the NI test is constancy assumption, that ...
Liu Qing Q a Experimental & Analytical Science, AbacusCloud, LLC , P. O.Box 236, Long Valley , NJ - - 2014
Abstract Clinical trials are mostly designed to provide data that allow direct inference of the underlying hypotheses. This, however, is not the case for non-inferiority trials where placebo controls are absent due to ethical considerations, resulting in the need for indirect inference about the underlying hypotheses of the treatment effect ...
Taha Mutasem O MO Department of Pharmaceutical Sciences, Faculty of Pharmacy, The University of Jordan, Amman, Jordan. Electronic address: - - 2014
Phosphoinositide 3-kinase gamma (PI3Kγ) is member of a family of enzymes involved in cancer pathogenesis. Accordingly, considerable efforts have been carried out to develop new PI3Kγ inhibitors. Towards this end we explored the pharmacophoric space of PI3Kγ using three diverse sets of inhibitors. Subsequently, we employed genetic algorithm-based QSAR analysis ...
Nagasaki Masayuki M a Biostatistics Group, Center for Product Evaluation, Pharmaceuticals and Medical Devices Agency , - - 2014
Abstract In recent years, development of biosimilar products has attracted considerable attention. Because of the structural complexity of biologics, it is difficult to demonstrate that a biosimilar product is identical to the reference product. Therefore, for the development of biosimilar products, we need to adopt an approach that is different ...
Abrahamyan Lusine L Toronto Health Economics and Technology Assessment Collaborative, University of Toronto, Toronto, Ontario, - - 2014
Hemophilia A is a rare, sex-linked genetic disorder treated with intravenous administration of factor VIII (FVIII) to prevent bleeding; however, approaches vary across and within countries. Value-of-information (VOI) methods identify situations in which the cost-benefit evidence is sufficient to adopt one treatment strategy over another; when the evidence is insufficient, ...
Foster Charles - - 2014
Property-based models of the ownership of body parts are common. They are inadequate. They fail to deal satisfactorily with many important problems, and even when they do work, they rely on ideas that have to be derived from deeper, usually unacknowledged principles. This article proposes that the parent principle is ...
Huang Yangxin Y Department of Epidemiology and Biostatistics, College of Public Health, University of South Florida, Tampa, FL, USA yhuang@health.usf.edu - - 2014
It is a common practice to analyze longitudinal data frequently arisen in medical studies using various mixed-effects models in the literature. However, the following issues may standout in longitudinal data analysis: (i) In clinical practice, the profile of each subject's response from a longitudinal study may follow a "broken stick" ...
Zhang Zhang Z CAS Key Laboratory of Genome Sciences and Information, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China. Electronic address: - - 2014
Biocuration involves adding value to biomedical data by the processes of standardization, quality control and information transferring (also known as data annotation). It enhances data interoperability and consistency, and is critical in translating biomedical data into scientific discovery. Although China is becoming a leading scientific data producer, biocuration is still ...
Alvarez Sergio S Florida Department of Agriculture and Consumer Services, 400 South Monroe Street, Tallahassee, FL 32399-0800, USA; University of Florida, P.O. Box 110240, Gainesville, FL 32611-0240, USA. Electronic address: - - 2014
At an estimated 206 million gallons, the Deepwater Horizon (DWH) is the largest marine oil spill in the history of the United States. In this paper we develop a series of random utility models of site choice by saltwater anglers in the Southeast US and estimate monetary compensation for recreational ...
Jackson Alice F AF Program in Neuroscience & Cognitive Science, University of Maryland, College Park, Maryland, USA; Department of Human Development and Quantitative Methodology, University of Maryland, College Park, Maryland, - - 2014
A thorough understanding of the EEG signal and its measurement is necessary to produce high quality data and to draw accurate conclusions from those data. However, publications that discuss relevant topics are written for divergent audiences with specific levels of expertise: explanations are either at an abstract level that leaves ...
Wang Xiang - - 2014
To control the southern corn leaf blight (SCLB), a severe disease of maize around the world, a combination of fungicides is often more potent than using individual fungicides. However, the number of possible combinations increases exponentially with the increase of the number of fungicides combined and their concentrations. It is ...
Tappenden Paul P Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, Sheffield, UK, - - 2014
Health economic models have become the primary vehicle for undertaking economic evaluation and are used in various healthcare jurisdictions across the world to inform decisions about the use of new and existing health technologies. Models are required because a single source of evidence, such as a randomised controlled trial, is ...
Duarte Fernanda F Science for Life Laboratory, Department of Cell and Molecular Biology (ICM), Uppsala University, BMC Box 596, S-751 24 Uppsala, - - 2014
Recent years have seen enormous progress in the development of methods for modeling (bio)molecular systems. This has allowed for the simulation of ever larger and more complex systems. However, as such complexity increases, the requirements needed for these models to be accurate and physically meaningful become more and more difficult ...
Jankowski Tomasz T Institute of Psychology, The John Paul II Catholic University of Lublin, Al. Racławickie 14, 20-950 Lublin, Poland. Electronic address: - - 2014
Mindfulness training has proven to be an efficacious therapeutic tool for a variety of clinical and nonclinical health problems and a booster of well-being. In this paper we propose a multi-level metacognitive model of mindfulness. We postulate and discuss following hypothesis: (1) mindfulness is related to the highest level of ...
Miller Benjamin B University Transportation Research Center, Region 2, 910 Marshak Hall, The City College of New York, New York, NY 10031, USA. Electronic address: - - 2014
Truck-based collection of municipal solid waste imposes significant negative externalities on cities and constrains the efficiency of separate collection of recyclables and organics and of unit-price-based waste-reduction systems. In recent decades, hundreds of municipal-scale pneumatic collection systems have been installed in Europe and Asia. Relatively few prior studies have compared ...
Gavin Daniel G DG Department of Geography, University of Oregon, Eugene, OR, 97403, - - 2014
I. II. Approaches for reconstructing refugia: strengths, limitations and recent advances III. IV. V. VI. References SUMMARY: Climate refugia, locations where taxa survive periods of regionally adverse climate, are thought to be critical for maintaining biodiversity through the glacial-interglacial climate changes of the Quaternary. A critical research need is to ...
Gensure Robert C RC Pediatric Endocrinology, Children's Hospital at Montefiore and Albert Einstein College of Medicine, Bronx, - - 2014
While the effects of PTHrP have been studied for almost 20 years, most of these studies have focused on effects on the termination of the anagen phase, giving an incomplete picture of the overall effect of PTHrP on the hair cycle. PTHrP was determined in several experimental models to promote ...
Richter Franziska F Institute of Pharmacology, Pharmacy and Toxicology, Department of Veterinary Medicine, University of Leipzig, 04103 Leipzig, - - 2014
Animal models are pivotal for studies of pathogenesis and treatment of disorders of the central nervous system which in its complexity cannot yet be modeled in vitro or using computer simulations. The choice of a specific model to test novel therapeutic strategies for a human disease should be based on ...
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