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Vyumvuhore Raoul R Université Paris-Sud, Faculty of Pharmacy, Group of Analytical Chemistry of Paris-Sud (GCAPS), 51100 Chatenay-Malabry, - - 2014
ABSTRACT. Dermatologists need to combine different clinically relevant characteristics for a better understanding of skin health. These characteristics are usually measured by different techniques, and some of them are highly time consuming. Therefore, a predicting model based on Raman spectroscopy and partial least square (PLS) regression was developed as a ...
Kulkarni Devdutt D Institute for Environmental Research, Biology V, RWTH Aachen University, Worringerweg 1, 52074 Aachen, Germany. Electronic address: - - 2014
Higher tiers of ecological risk assessment (ERA) consider population and community-level endpoints. At the population level, the phenomenon of density dependence is one of the most important ecological processes that influence population dynamics. In this study, we investigated how different mechanisms of density dependence would influence population-level ERA of the ...
Klingenberg Christian Peter CP Faculty of Life Sciences, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK - - 2014
Although most studies on integration and modularity have focused on variation among individuals within populations or species, this is not the only level of variation for which integration and modularity exist. Multiple levels of biological variation originate from distinct sources: genetic variation, phenotypic plasticity resulting from environmental heterogeneity, fluctuating asymmetry ...
Drewnowski Adam A Center for Public Health Nutrition, University of Washington, Seattle, Washington. Electronic address: - - 2014
Studies have tried to link obesity rates and physical activity with multiple aspects of the built environment. To determine the relation between residential property values and multiple perceived (self-reported) measures of the obesogenic environment. The Seattle Obesity Study (SOS) used a telephone survey of a representative, geographically distributed sample of ...
Hatakeyama Y Y Yutaka Hatakeyama, Center of Medical Information Science, Kochi University Medical School, Oko-cho Kohasu, Nankoku, Kochi, Kochi 783-8505, Japan, E-mail: - - 2014
Objectives: We developed a robust, long-term clinical prediction model to predict conditions leading to early diabetes using laboratory values other than blood glucose and insulin levels. Our model protects against missing data and noise that occur during long-term analysis. Methods: Results of a 75-g oral glucose tolerance test (OGTT) were ...
Naeem Awan Muhammad M WWF Pakistan, Regional Office, Azad Kashmir, Muzaffarabad, Pakistan. - - 2014
The cheer pheasant Catreus wallichi is a globally threatened species that inhabits the western Himalayas. Though it is well established that the species is threatened and its numbers declining, updated definitive estimates are lacking, so in 2011, we conducted a survey to assess the density, population size, and threats to ...
Rodriguez Alex A SISSA (Scuola Internazionale Superiore di Studi Avanzati), via Bonomea 265, I-34136 Trieste, - - 2014
Cluster analysis is aimed at classifying elements into categories on the basis of their similarity. Its applications range from astronomy to bioinformatics, bibliometrics, and pattern recognition. We propose an approach based on the idea that cluster centers are characterized by a higher density than their neighbors and by a relatively ...
Sarkar Abhra A Department of Statistics, Texas A&M University, College Station, Texas 77843-3143, - - 2014
We consider the problem of robust estimation of the regression relationship between a response and a covariate based on sample in which precise measurements on the covariate are not available but error-prone surrogates for the unobserved covariate are available for each sampled unit. Existing methods often make restrictive and unrealistic ...
Chiu Chun-Huo CH Institute of Statistics, National Tsing Hua University, Hsin-Chu 30043, - - 2014
It is difficult to accurately estimate species richness if there are many almost undetectable species in a hyper-diverse community. Practically, an accurate lower bound for species richness is preferable to an inaccurate point estimator. The traditional nonparametric lower bound developed by Chao (1984, Scandinavian Journal of Statistics 11, 265-270) for ...
Li Mei M Centre for Protolife Research, Centre for Organized Matter Chemistry, School of Chemistry, University of Bristol, Bristol BS8 1TS, - - 2014
This review discusses recent advances in the design and construction of protocell models based on the self-assembly or microphase separation of non-lipid building blocks. We focus on strategies involving partially hydrophobic inorganic nanoparticles (colloidosomes), protein-polymer globular nano-conjugates (proteinosomes), amphiphilic block copolymers (polymersomes), and stoichiometric mixtures of oppositely charged biomolecules and ...
Wong Gerard G Baker IDI Heart and Diabetes Institute, Victoria, Australia. Department of Computing and Information Systems, The University of Melbourne, Victoria, Australia. - - 2014
Recent advances in high-throughput lipid profiling by liquid chromatography electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS) have made it possible to quantify hundreds of individual molecular lipid species (e.g. fatty acyls, glycerolipids, glycerophospholipids, sphingolipids) in a single experimental run for hundreds of samples. This enables the lipidome of large cohorts of ...
Shakouri Mahmoud M Department of Mechanical & Industrial Engineering, Louisiana State University, Baton Rouge, LA 70803, - - 2014
This paper investigates the effect of changing work zone configurations and traffic density on performance variables and subjective workload. Data regarding travel time, average speed, maximum percent braking force and location of lane changes were collected by using a full size driving simulator. The NASA-TLX was used to measure self-reported ...
Hoppel Magdalena M University of Vienna, Research Platform, Characterisation of Drug Delivery Systems on Skin and Investigations of Involved Mechanisms, Althanstraße 14, Vienna 1090, - - 2014
The physical presence of surfactants in the skin is linked to their skin irritation potential. Combined ATR-FTIR spectroscopy and tape stripping experiments in vitro on porcine ear skin were used to investigate the spatial distribution of sodium lauryl ether sulfate (SLES) in the stratum corneum and to assess its effects ...
Gutierrez María Florencia MF Instituto Nacional de Limnología (CONICET-UNL), Ciudad Universitaria, 3000, Santa Fe, Argentina, - - 2014
Predator-prey relationships are determining factors in sustaining community structure but xenobiotics, including pesticides, have the potential to alter them, causing imbalances at the ecosystem level. Although invertebrate predation on zooplankton is of high importance in shallow lakes, there is still little information regarding disturbances on this trophic interaction. This work ...
Barraquand Frédéric F Centre d'Etudes Biologiques de Chizé, CNRS, Beauvoir-sur-Niort, France; Department of Arctic and Marine Biology, University of Tromsø, - - 2014
Population cycles in voles are often thought to be generated by one-year delayed density-dependence on the annual population growth rate. In common voles, however, it has been suggested by Turchin (2003) that some populations exhibit first-order cycles, resulting from strong overcompensation (i.e. carrying capacity overshoots in peak years, with only ...
Miguel Eve E Cirad-ES,AGIRs, (Animal et Gestion Intégrée des Risques/Animal and Integrated Risk Management), Montpellier, France; CNRS-Centre d'Ecologie Fonctionnelle et Evolutive - UMR 5175, Montpellier, France; Cirad-ES, AGIRs-RP-PCP, Harare P.O. Box 1378, Zimbabwe. Electronic address: - - 2014
The sharing of habitat by wild and domestic animals may result in pathogen transmission, notably via ectoparasite vectors such as ticks. Interfaces between protected and communal lands constitute sharp transitions between areas occupied by host communities that are extremely contrasted in terms of composition, diversity and density. Empirical characterizations of ...
Harpole Jared K - - 2014
Exploratory data analysis (EDA) can reveal important features of underlying distributions, and these features often have an impact on inferences and conclusions drawn from data. Graphical analysis is central to EDA, and graphical representations of distributions often benefit from smoothing. A viable method of estimating and graphing the underlying density ...
Bossard Robert L RL Westminster College, Salt Lake City, UT 84105, U.S.A.. - - 2014
Numbers of flea (Siphonaptera) species (flea species richness) on individual mammals should be higher on large mammals, mammals with dense populations, and mammals with large geographic ranges, if mammals are islands for fleas. I tested the first two predictions with regressions of H. J. Egoscue's trapping data on flea species ...
Sau Arunashis A Imperial - - 2014
The European Society of Cardiology's guidelines "present all the relevant evidence on a particular clinical issue" to clinicians, being designed to be "helpful in everyday clinical medical decision-making".Statements are accompanied by one of three Levels of Evidence: A (multiple randomised controlled trials (RCTs) or meta-analyses), B (large non-randomised studies or ...
Moody Jeffrey W JW Mechanical and Aerospace Engineering - - 2014
In the current literature, the life cycle, technoeconomic, and resource assessments of microalgae-based biofuel production systems have relied on growth models extrapolated from laboratory-scale data, leading to a large uncertainty in results. This type of simplistic growth modeling overestimates productivity potential and fails to incorporate biological effects, geographical location, or ...
Kapourchali Fatemeh Ramezani FR Fatemeh Ramezani Kapourchali, Mohammed H Moghadasian, International Nutrition Research Inc., Winnipeg, MB R3T2G4, - - 2014
In this mini-review several commonly used animal models of atherosclerosis have been discussed. Among them, emphasis has been made on mice, rabbits, pigs and non-human primates. Although these animal models have played a significant role in our understanding of induction of atherosclerotic lesions, we still lack a reliable animal model ...
Yao Ling L State Key Laboratory of Resources and Environmental Information System, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, No.11A, Datun Road, Chaoyang, Beijing, 100101, - - 2014
Air quality problems caused by atmospheric particulate have drawn broad public concern in the global scope. In the paper, the spatiotemporal distributions of fine particle (PM2.5) and inhalable particle (PM10) concentrations estimated with the artificial neural network (ANN) over China during 2006 to 2010 have been discussed. Most high PM10 ...
Kohut Sviataslau V SV Department of Chemistry, The University of Western Ontario, London, Ontario N6A 5B7, - - 2014
We describe a method for constructing a hierarchy of model potentials approximating the functional derivative of a given orbital-dependent exchange-correlation functional with respect to electron density. Each model is derived by assuming a particular relationship between the self-consistent solutions of Kohn-Sham (KS) and generalized Kohn-Sham (GKS) equations for the same ...
Exarchos Konstantinos - - 2014
Progression of atherosclerotic process constitutes a serious and quite common condition owed to accumulation of fatty materials in the arterial wall, consequently posing serious cardiovascular complications. In this work, we assemble and analyze a multitude of heterogeneous data in order to model the progression of atherosclerosis (ATS) in coronary vessels. ...
Roy Partha Pratim PP Department of Pharmacy, Guru Ghasidas Vishwavidyalaya, Bilaspur 495009, - - 2014
The objective of the present work was tantamount to explain the antiperoxidative potential and structural requirements of twenty-eight structurally diverse classes of antioxidants on docetaxel-induced lipid peroxidation. Both experimental and computational approaches were taken to the work. The experiments were performed in vitro and goat liver was used as a ...
Pidgeon Anna M AM SILVIS Lab, Department of Forest and Wildlife Ecology, University of Wisconsin-Madison, Madison, WI, 53706, U.S.A.. - - 2014
As people encroach increasingly on natural areas, one question is how this affects avian biodiversity. The answer to this is partly scale-dependent. At broad scales, human populations and biodiversity concentrate in the same areas and are positively associated, but at local scales people and biodiversity are negatively associated with biodiversity. ...
Guo Yachong Y Departament d'Enginyeria Química, Universitat Rovira i Virgili, Av. dels Paisos Catalans 26, 43007 Tarragona, - - 2014
Coarse-grained model for saturated phospholipids: 1,2-didecanoyl-sn-glycero-3-phosphocholine (DCPC), 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC), 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC), 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) and unsaturated phospholipids: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC), 1,2- dioleoyl-sn-glycero-3-phosphocholine (DOPC) is introduced within the single chain mean field theory. A single set of parameters adjusted for DMPC bilayers gives an adequate description of equilibrium and mechanical properties ...
Hedges Larry V LV Institute for Policy Research at Northwestern University, Evanston, IL, - - 2014
Cluster-randomized experiments that assign intact groups such as schools or school districts to treatment conditions are increasingly common in educational research. Such experiments are inherently multilevel designs whose sensitivity (statistical power and precision of estimates) depends on the variance decomposition across levels. This variance decomposition is usually summarized by the ...
Sodt Alexander J AJ National Heart, Lung, and Blood Institute, National Institutes of Health, Rockville, Maryland. Electronic address: - - 2014
Molecular dynamics simulations of an amphipathic helix embedded in a lipid bilayer indicate that it will induce substantial positive curvature (e.g., a tube of diameter 20 nm at 16% surface coverage). The induction is twice that of a continuum model prediction that only considers the shape of the inclusion. The discrepancy ...
Erdem Seda S Economics Division, Stirling Management School, University of Stirling, Stirling, - - 2014
An extensive literature has established that it is common for respondents to ignore attributes of the alternatives within choice experiments. In most of the studies on attribute non-attendance, it is assumed that respondents consciously (or unconsciously) ignore one or more attributes of the alternatives, regardless of their levels. In this ...
Vidal Natalia P - - 2014
The lipids of 16 farmed and wild European sea bass (Dicentrarchus labrax) samples were studied by Fourier transform infrared (FTIR) spectroscopy. The spectroscopic parameters which would be useful when distinguishing between both fish origins were analysed. It was shown, for the first time, that the frequency and the ratio between ...
Charland Scott L - - 2014
To evaluate the relationship between low-density lipoprotein cholesterol (LDL-C) concentration and the annual incidence of combined coronary heart disease (CHD) events—death or nonfatal myocardial infarction (NFMI)—by using sigmoidal maximal effect (sEmax) modeling of published data in various populations at risk for CHD events, and to use the best performing sEmax ...
Zhao Laijun - - 2014
Based on the current status of research on tradable emission rights futures, this paper introduces basic market-related assumptions for China's interprovincial air pollution control problem. The authors construct an interprovincial air pollution control model based on futures prices: the model calculated the spot price of emission rights using a classic ...
Löffler Tina - - 2014
Beyond cognitive decline, Alzheimer's disease (AD) is characterized by numerous neuropathological changes in the brain. Although animal models generally do not fully reflect the broad spectrum of disease-specific alterations, the APPSL mouse model is well known to display early plaque formation and to exhibit spatial learning and memory deficits. However, ...
Van Lehn Reid C - - 2014
Amphiphilic, monolayer-protected gold nanoparticles (AuNPs) have recently been shown to insert into and fuse with lipid bilayers, driven by the hydrophobic effect. The inserted transmembrane state is stabilized by the "snorkeling'' of charged ligand end groups out of the bilayer interior. This snorkeling process is facilitated by the backbone flexibility ...
Thompson Jason J a Monash University Accident Research Centre (MUARC), Monash Injury Research Institute , Room 310, Building 70, Level 3, Clayton Campus, Vic 3800 , - - 2014
ABSTRACT Objective: Increasing levels of active transport provides benefits in relation to chronic disease and emissions reduction, but it may be associated with an increased risk of road trauma. The safety in numbers (SiN) effect is often regarded as a solution to this issue, however, the mechanisms underlying its influence ...
Barnard Donald R DR Center for Medical, Agricultural, and Veterinary Entomology, USDA-ARS, Gainesville, FL 32608, USA. Electronic address: - - 2014
In traditional vector surveillance systems, adult mosquito density and the rate of mosquito-human host contact are estimated from the mosquito numbers captured in mechanical traps. But the design of the traps, their placement in the habitat and operating time, microclimate, and other environmental factors bias mosquito responses such that trapped ...
McCabe Patrick - - 2014
We describe the method of kernel density estimation (KDE) and apply it to molecular structure data. KDE is a quite general non-parametric statistical method suitable even for multi-modal data. The method generates smooth probability density function (PDF) representations and finds application in diverse fields such as signal processing and econometrics. ...
Dumont Grégory - - 2014
Population density models used to describe the evolution of neural populations in a phase space are closely related to the single neuron model that describes the individual trajectories of the neurons of the population and which gives in particular the phase-space where the computations are made. Based on a transformation ...
Kakara Makoto M Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, - - 2014
HMG-CoA reductase inhibitors are available for use in low-density lipoprotein-cholesterol (LDL-C) lowering therapy. The purposes of this study were to develop a population pharmacodynamic (PPD) model to describe the time course for the LDL-C lowering effects of statins and assess the efficacy of combination therapy based on electronic medical records. ...
Nagle John F JF Department of Physics, Carnegie Mellon University, Pittsburgh, PA 15213, USA. Electronic address: - - 2014
Values of the bending modulus KC are reviewed, and possible causes for the considerable differences are discussed. One possible cause is the use of glucose and sucrose in the classical micromechanical manipulation and shape analysis methods. New data, using the more recent low angle X-ray method, are presented that do ...
Cropp Roger R School of Environment, Griffith University, Nathan, - - 2014
Humpback whales are iconic mammals at the top of the Antarctic food chain. Their large reserves of lipid rich tissues such as blubber predispose them to accumulation of lipophilic contaminants throughout their lifetime. Changes in the volumes and distribution of lipids in humpback whales, particularly during migration, could play an ...
Virkkala Raimo R Finnish Environment Institute, Natural Environment Centre, Mechelininkatu 34 a, P.O. Box 140, Helsinki, FI-00251, - - 2014
Climate change has been shown to cause poleward range shifts of species. These shifts are typically demonstrated using presence-absence data, which can mask the potential changes in the abundance of species. Moreover, changes in the mean centre of weighted density of species are seldom examined, and comparisons between these two ...
Van Leeuwen Mpc M Department of Periodontology (ACTA), Amsterdam, the Netherlands; Dentistry Clinic, Bussum, the - - 2014
The purpose of this review was to systematically evaluate the effects of an alcohol vehicle solution (V-Sol) compared with an essential-oils mouthwash (EOMW) and if available with a water-based control (WC) on plaque, gingival inflammation parameters and extrinsic tooth staining. The PubMed-MEDLINE, Cochrane-CENTRAL and EMBASE databases were searched. Where appropriate, ...
Pizzi Laura T LT Thomas Jefferson University, 901 Walnut Street, Suite 911, Philadelphia, PA, 19107, USA, - - 2014
Preterm birth (PTB) is a costly public health problem in the USA. The PREGNANT trial tested the efficacy of vaginal progesterone (VP) 8 % gel in reducing the likelihood of PTB among women with a short cervix. We calculated the costs and cost effectiveness of VP gel versus placebo using decision ...
Modanu Maria M Integrative Behaviour and Neuroscience Group, Dept of Biological Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto ON, Canada M1C1A4; Department of Neurobiology & Behavior, 215 Tower Rd, Cornell University, Ithaca, NY USA 14853. Electronic address: - - 2014
Sibling cannibalism occurs across diverse taxa and can affect population size and structure, as well as the fitness of parents and the cannibal, via density effects and variation in individual propensity to cannibalize. We examined these effects on sibling cannibalism in juveniles of a web-building spider (Latrodectus hasselti, Australian redbacks). ...
Betini Gustavo S GS Department of Integrative Biology, University of Guelph, Guelph, Ontario, N1G 2W1, - - 2014
1.In seasonal populations, vital rates are not only determined by the direct effects of density at the beginning of each season, but also by density at the beginning of past seasons. Such delayed density-dependence can arise via non-lethal effects on individuals that carry-over to influence per capita rates. 2.In this ...
Fazzari Melissa J MJ a Department of Biostatistics , Winthrop University Hospital , Mineola , N.Y. , - - 2014
Abstract Clinical trials in the context of comparative effectiveness research (CER) are often conducted to evaluate health outcomes under real-world conditions and standard health care settings. In such settings, three-level hierarchical study designs are increasingly common. For example, patients may be nested within treating physicians, who in turn are nested ...
Shinozaki Tomohiro T Department of Biostatistics, School of Public Health, The University of Tokyo, Tokyo, 113-0033, - - 2014
For the estimation of controlled direct effects (i.e., direct effects controlling intermediates that are set at a fixed level for all members of the population) without bias, two fundamental assumptions must hold: the absence of unmeasured confounding factors for treatment and outcome and for intermediate variables and outcome. Even if ...
Hu Andrew A Department of Mechanical Engineering, University of Connecticut, Storrs, CT 06269-3139, - - 2014
Lipid-based nanodiscs (bicelles) are able to form in mixtures of long- and short-chain lipids. Initially, they are of uniform size but grow upon dilution. Previously, nanodisc growth kinetics have been studied using time-resolved small angle neutron scattering (SANS), a technique which is not well suited for probing their change in ...
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