Search Results
Results 1 - 50 of 1896
1 2 3 4 5 6 7 8 9 10 >
Cropp Roger R School of Environment, Griffith University, Nathan, - - 2014
Humpback whales are iconic mammals at the top of the Antarctic food chain. Their large reserves of lipid rich tissues such as blubber predispose them to accumulation of lipophilic contaminants throughout their lifetime. Changes in the volumes and distribution of lipids in humpback whales, particularly during migration, could play an ...
Virkkala Raimo R Finnish Environment Institute, Natural Environment Centre, Mechelininkatu 34 a, P.O. Box 140, Helsinki, FI-00251, - - 2014
Climate change has been shown to cause poleward range shifts of species. These shifts are typically demonstrated using presence-absence data, which can mask the potential changes in the abundance of species. Moreover, changes in the mean centre of weighted density of species are seldom examined, and comparisons between these two ...
Van Leeuwen Mpc M Department of Periodontology (ACTA), Amsterdam, the Netherlands; Dentistry Clinic, Bussum, the - - 2014
The purpose of this review was to systematically evaluate the effects of an alcohol vehicle solution (V-Sol) compared with an essential-oils mouthwash (EOMW) and if available with a water-based control (WC) on plaque, gingival inflammation parameters and extrinsic tooth staining. The PubMed-MEDLINE, Cochrane-CENTRAL and EMBASE databases were searched. Where appropriate, ...
Pizzi Laura T LT Thomas Jefferson University, 901 Walnut Street, Suite 911, Philadelphia, PA, 19107, USA, - - 2014
Preterm birth (PTB) is a costly public health problem in the USA. The PREGNANT trial tested the efficacy of vaginal progesterone (VP) 8 % gel in reducing the likelihood of PTB among women with a short cervix. We calculated the costs and cost effectiveness of VP gel versus placebo using decision ...
Modanu Maria M Integrative Behaviour and Neuroscience Group, Dept of Biological Sciences, University of Toronto Scarborough, 1265 Military Trail, Toronto ON, Canada M1C1A4; Department of Neurobiology & Behavior, 215 Tower Rd, Cornell University, Ithaca, NY USA 14853. Electronic address: - - 2014
Sibling cannibalism occurs across diverse taxa and can affect population size and structure, as well as the fitness of parents and the cannibal, via density effects and variation in individual propensity to cannibalize. We examined these effects on sibling cannibalism in juveniles of a web-building spider (Latrodectus hasselti, Australian redbacks). ...
Betini Gustavo S GS Department of Integrative Biology, University of Guelph, Guelph, Ontario, N1G 2W1, - - 2014
1.In seasonal populations, vital rates are not only determined by the direct effects of density at the beginning of each season, but also by density at the beginning of past seasons. Such delayed density-dependence can arise via non-lethal effects on individuals that carry-over to influence per capita rates. 2.In this ...
Fazzari Melissa J MJ a Department of Biostatistics , Winthrop University Hospital , Mineola , N.Y. , - - 2014
Abstract Clinical trials in the context of comparative effectiveness research (CER) are often conducted to evaluate health outcomes under real-world conditions and standard health care settings. In such settings, three-level hierarchical study designs are increasingly common. For example, patients may be nested within treating physicians, who in turn are nested ...
Shinozaki Tomohiro T Department of Biostatistics, School of Public Health, The University of Tokyo, Tokyo, 113-0033, - - 2014
For the estimation of controlled direct effects (i.e., direct effects controlling intermediates that are set at a fixed level for all members of the population) without bias, two fundamental assumptions must hold: the absence of unmeasured confounding factors for treatment and outcome and for intermediate variables and outcome. Even if ...
Hu Andrew A Department of Mechanical Engineering, University of Connecticut, Storrs, CT 06269-3139, - - 2014
Lipid-based nanodiscs (bicelles) are able to form in mixtures of long- and short-chain lipids. Initially, they are of uniform size but grow upon dilution. Previously, nanodisc growth kinetics have been studied using time-resolved small angle neutron scattering (SANS), a technique which is not well suited for probing their change in ...
Leingärtner Annette A Department of Animal Ecology and Tropical Biology, Biocentre, University of Würzburg, Am Hubland, 97074, Würzburg, Germany, - - 2014
Species richness patterns along altitudinal gradients are well-documented ecological phenomena, yet very little data are available on how environmental filtering processes influence the composition and traits of butterfly assemblages at high altitudes. We have studied the diversity patterns of butterfly species at 34 sites along an altitudinal gradient ranging from ...
Moja Lorenzo L Clinical Epidemiology Unit, IRCCS Orthopedic Institute Galeazzi, Milan, Italy; Department of Biomedical Science for Health, University of Milan, Milan, - - 2014
Animal experiments should be appropriately designed, correctly analysed, and transparently reported to increase their scientific validity and maximise the knowledge gained from each experiment. This systematic review of animal experiments investigating statins evaluates their quality of reporting and methodological aspects as well as their implications for the conduction of meta-analyses. ...
Faure Gérôme G CEA, DAM, DIF, F-91297 Arpajon, - - 2014
This work proposes a coarse grained description of molecular systems based on mesoparticles representing several molecules, where interactions between mesoparticles are modelled by an interparticle potential of molecular type. Since strong non-equilibrium situations over a wide range of pressure and density are targeted, the internal compressibility of the mesoparticles has ...
Martínez-Valdivieso Damián D IFAPA-Centro La Mojonera, Plant Breeding and Biotechnology, Almería, - - 2014
Efforts through conventional breeding to improve the mineral content in horticultural crops have not always been successful mainly due to the fact that standard analytical methods are both costly and time-consuming. We investigated the feasibility of applying near infrared reflectance spectroscopy (NIRS) to the estimation of essential mineral composition in ...
Miller Aaron W AW Biomedical Informatics Research Center, Marshfield Clinic Research Foundation, 1000 North Oak Avenue, Marshfield, WI, 54449, USA. Electronic address: - - 2014
We aim to quantify HMG-CoA reductase inhibitor (statin) prescriber-intended exposure-time using a generalizable algorithm that interrogates data stored in the electronic health record (EHR). This study was conducted using the Marshfield Clinic (MC) Personalized Medicine Research Project (PMRP) a central Wisconsin-based population and biobank with, on average, 30 years of ...
McHugh R Kathryn RK Division of Alcohol and Drug Abuse, McLean Hospital, Belmont, Massachusetts, Department of Psychiatry, Harvard Medical School, Boston, - - 2014
ABSTRACT. Objective: Self-report measures of alcohol misuse and alcohol use disorders are valuable assessment tools for both research and clinical practice settings. However, readability is often overlooked when establishing the validity of these measures, which may result in measures written at a reading-grade level that is higher than the ability ...
Bolko Katarina - - 2014
One of the greatest challenges in the pharmaceutical science is the improvement of oral bioavailability of poorly soluble drugs. Lately, one of the most attractive approaches has been formulation of lipid based drug delivery systems. However, the emerging popularity of these systems in the last decade has brought to light ...
Girod Aline A Institut de Police Scientifique, University of Lausanne, Bâtochime, CH-1015 Lausanne, Switzerland. Electronic address: - - 2014
Lipids available in fingermark residue represent important targets for enhancement and dating techniques. While it is well known that lipid composition varies among fingermarks of the same donor (intra-variability) and between fingermarks of different donors (inter-variability), the extent of this variability remains uncharacterized. Thus, this work aimed at studying qualitatively ...
Jin Seok-Joon SJ Department of Anesthesiology, Ulsan University College of Medicine Asan Medical Center, Pungnap-2-dong, 88 Olympic-ro 43-gil, Sonpa-gu, Seoul, 138-736, - - 2014
The pharmacokinetics of simvastatin is complex with multiple peaks in the absorption phase, which cannot be adequately described by a conventional first order absorption model. The biotransformation of simvastatin into simvastatin acid, an active metabolite, is reversible. This study evaluated the pharmacokinetics of simvastatin and simvastatin acid, focusing on the ...
Gong Gordon G F. Marie Hall Institute for Rural and Community Health, Texas Tech University Health Sciences Center, Lubbock, TX, USA. Electronic address: - - 2014
Exposure to arsenic causes many diseases. Most Americans in rural areas use groundwater for drinking, which may contain arsenic above the currently allowable level, 10µg/L. It is cost-effective to estimate groundwater arsenic levels based on data from wells with known arsenic concentrations. We compared the accuracy of several commonly used ...
Inthout Joanna - - 2014
The DerSimonian and Laird approach (DL) is widely used for random effects meta-analysis, but this often results in inappropriate type I error rates. The method described by Hartung, Knapp, Sidik and Jonkman (HKSJ) is known to perform better when trials of similar size are combined. However evidence in realistic situations, ...
Ferrer-Admetlla Anna A Department of Integrative Biology, University of California at Berkeley, Berkeley, California, United States of America; School of Life Sciences and Institute of Bioengineering, EPFL, Lausanne, Switzerland (current affiliation); Department of Biology and Biochemistry, University of Fribourg, Fribourg, Switzerland (current affiliation); Swiss Institute of Bioinformatics (SIB), Switzerland (current affiliation); Departments of Biology and Bioinformatics, University of Copenhagen, Copenhagen, - - 2014
We present a new haplotype-based statistic (nSL) for detecting both soft and hard sweeps in population genomic data from a single population. We compare our new method to classic single-population haplotype and sfs-based methods and show that it is more robust, particularly to recombination rate variation. However, all statistics show ...
Cornell John E - - 2014
A primary goal of meta-analysis is to improve the estimation of treatment effects by pooling results of similar studies. This article explains how the most widely used method for pooling heterogeneous studies-the DerSimonian-Laird (DL) estimator-can produce biased estimates with falsely high precision. A classic example is presented to show that ...
Doktorovova Slavomira S Department of Biology and Environment, School of Life and Environmental Sciences, (ECVA, UTAD), University of Trás-os-Montes and Alto Douro;Quinta de Prados;P-5001-801 Vila Real, Portugal; Institute of Biotechnology and Bioengineering, Centre of Genomics and Biotechnology, University of Trás-os-Montes and Alto Douro (IBB/CGB-UTAD), 5001-801 Vila-Real, - - 2014
Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) were developed as alternative to other colloidal carriers. They were designed to overcome lipid nanoemulsions and liposomes in stability and ability to control the release of an encapsulated substance, and at the same time to be better tolerated than polymeric nanoparticles. ...
Mosconi E E Department of Computer Science, University of Verona, Verona, - - 2014
Proton magnetic resonance spectroscopy (MRS) is a sensitive method for investigating the biochemical compounds in a tissue. The interpretation of the data relies on the quantification algorithms applied to MR spectra. Each of these algorithms has certain underlying assumptions and may allow one to incorporate prior knowledge, which could influence ...
Pati Debdeep D Department of Statistical Science, Duke University - - 2014
We consider the problem of robust Bayesian inference on the mean regression function allowing the residual density to change flexibly with predictors. The proposed class of models is based on a Gaussian process prior for the mean regression function and mixtures of Gaussians for the collection of residual densities indexed ...
Kabatas B B Eurasia Institute of Earth Sciences, Istanbul Technical University, Istanbul, - - 2014
Sahara-originated dust is the most significant natural source of particulate matter; however, this contribution is still unclear in the Eastern Mediterranean especially in Western Turkey, where significant industrial sources and metropolitan areas are located. The Real-time Air Quality Modeling System (RAQMS) is utilized to explore the possible effects of Saharan ...
McGhee Peter P Entomology, Michigan State University, 106 CIPS, 578 Wilson Rd, East Lansing, Michigan, United - - 2014
Isomate® CM MIST aerosol emitters (Pacific BioControl Corp, Vancouver, WA) containing 36 grams of codlemone, (E, E)-8,10-dodecadien-1-ol, were deployed at various densities in a commercial apple orchard to generate dosage-response profiles in order to elucidate the behavioral mechanism of disruption. Moth captures decreased asymptotically as Isomate® CM MIST densities increased. ...
Thorner Jaqueline J University of New England (UNE), School of Rural and Environmental Sciences, Armidale, New South Wales, Australia ; National Marine Science Centre, Southern Cross University (SCU), Coffs Harbour, New South Wales, - - 2014
Intertidal rocky reefs are complex and rich ecosystems that are vulnerable to even the smallest fluctuations in sea level. We modelled habitat loss associated with sea level rise for intertidal rocky reefs using GIS, high-resolution digital imagery, and LIDAR technology at fine-scale resolution (0.1 m per pixel). We used projected ...
Bhattacharya Bonhi S BS Department of Mathematics and Statistics, University of Reading, Whiteknights, Reading, UK, RG6 - - 2014
Cholesterol is one of the key constituents for maintaining the cellular membrane and thus the integrity of the cell itself. In contrast high levels of cholesterol in the blood is known to be a major risk factor in the development of cardiovascular disease. We formulate a deterministic nonlinear ordinary differential ...
Walker Ryan G RG University of Cincinnati, United - - 2014
Apolipoprotein (apo)AIV plays important roles in dietary lipid and glucose metabolism and knowledge of its structure is required to fully understand the molecular basis of these functions. However, typical of the entire class of exchangeable apolipoproteins, its dynamic nature and affinity for lipid has posed challenges to traditional high-resolution structural ...
Hill Jason M JM Pennsylvania Cooperative Fish and Wildlife Research Unit, Pennsylvania State University, University Park, PA, 16802, U.S.A.. - - 2014
Organisms can be affected by processes in the surrounding landscape outside the boundary of habitat areas and by local vegetation characteristics. There is substantial interest in understanding how these processes affect populations of grassland birds, which have experienced substantial population declines. Much of our knowledge regarding patterns of occupancy and ...
Sousa Joana J Departamento de Antropologia, Faculdade de Ciências Sociais e Humanas (FCSH), Universidade Nova de Lisboa, Av. Berna, 26-C, 1069-061, Lisbon, - - 2014
The present study aimed to gather baseline information about chimpanzee nesting and density in Lagoas de Cufada Natural Park (LCNP), in Guinea-Bissau. Old and narrow trails were followed to estimate chimpanzee density through marked-nest counts and to test the effect of canopy closure (woodland savannah, forest with a sparse canopy, ...
McCarthy Michael T MT Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, - - 2014
Hypersensitivity to DNaseI digestion is a hallmark of open chromatin and DNaseI-seq allows the genome-wide identification of regions of open chromatin. Interpreting these data is challenging, largely because of inherent variation in signal-to-noise ratio (SNR) between datasets. We have developed PeaKDEck, a peak calling program that distinguishes signal from noise ...
Mallet Delphine D IFREMER, Unité de Recherche Lagons, Ecosystèmes et Aquaculture Durable en Nouvelle Calédonie (LEAD-NC), Nouméa, New Caledonia ; EA 4243 LIVE, Université de la Nouvelle-Calédonie, Nouméa, New - - 2014
Estimating diversity and abundance of fish species is fundamental for understanding community structure and dynamics of coral reefs. When designing a sampling protocol, one crucial step is the choice of the most suitable sampling technique which is a compromise between the questions addressed, the available means and the precision required. ...
Kang Eun Yong EY Department of Computer Science, University of California, Los Angeles, Los Angeles, California, United States of - - 2014
Identifying environmentally-specific genetic effects is a key challenge in understanding the structure of complex traits. Model organisms play a crucial role in the identification of such gene-by-environment interactions, as a result of the unique ability to observe genetically similar individuals across multiple distinct environments. Many model organism studies examine the ...
Molnár Péter K PK Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of - - 2014
Allee effects are an important component in the population dynamics of numerous species. Accounting for these Allee effects in population viability analyses generally requires estimates of low-density population growth rates, but such data are unavailable for most species and particularly difficult to obtain for large mammals. Here, we present a ...
Ahmad Shamsad S 0000-0001-7939-7319 Civil and Environmental Engineering Department, King Fahd University of Petroleum and Minerals, P.O. Box 1403, Dhahran 31261, Saudi - - 2014
The accuracy in the measurement of the rate of corrosion of steel in concrete depends on many factors. The high resistivity of concrete makes the polarization data erroneous due to the Ohmic drop. The other source of error is the use of an arbitrarily assumed value of the Stern-Geary constant ...
Sung Yun Ju YJ Division of Biostatistics, Washington University School of Medicine in St. Louis St. Louis, MO, - - 2014
Gene-environment interaction (GEI) analysis can potentially enhance gene discovery for common complex traits. However, genome-wide interaction analysis is computationally intensive. Moreover, analysis of longitudinal data in families is much more challenging due to the two sources of correlations arising from longitudinal measurements and family relationships. GWIS of longitudinal family data ...
Barra Adriano A Dipartimento di Fisica, Sapienza Università di - - 2014
How does immigrant integration in a country change with immigration density? Guided by a statistical mechanics perspective we propose a novel approach to this problem. The analysis focuses on classical integration quantifiers such as the percentage of jobs (temporary and permanent) given to immigrants, mixed marriages, and newborns with parents ...
Hulovatyy Yuriy Y Department of Computer Science and Engineering, ECK Institute for Global Health, and Interdisciplinary Center for Network Science and Applications, University of Notre Dame, Notre Dame, Indiana, United States of - - 2014
Protein interaction networks (PINs) are often used to "learn" new biological function from their topology. Since current PINs are noisy, their computational de-noising via link prediction (LP) could improve the learning accuracy. LP uses the existing PIN topology to predict missing and spurious links. Many of existing LP methods rely ...
Herrando-Pérez Salvador S The Environment Institute and School of Earth and Environmental Sciences, University of Adelaide, South Australia, Australia; Department of Biogeography and Global Change, National Museum of Natural Sciences, Spanish Research Council (CSIC), Madrid, - - 2014
The use of long-term population data to separate the demographic role of climate from density-modified demographic processes has become a major topic of ecological investigation over the last two decades. Although the ecological and evolutionary mechanisms that determine the strength of density feedbacks are now well understood, the degree to ...
Weissbrod Lior L Zinman Institute of Archaeology, University of Haifa, Haifa, - - 2014
Modern rapidly expanding cities generate intricate patterns of species diversity owing to immense complexity in urban spatial structure and current growth trajectories. We propose to identify and uncouple the drivers that give rise to these patterns by looking at the effect of urbanism on species diversity over a previously unexplored ...
Huntsman Brock M BM Division of Forestry and Natural Resources, West Virginia University, Morgantown, West Virginia, United States of - - 2014
Spatial population models predict strong density-dependence and relatively stable population dynamics near the core of a species' distribution with increasing variance and importance of density-independent processes operating towards the population periphery. Using a 10-year data set and an information-theoretic approach, we tested a series of candidate models considering density-dependent and ...
Vock David M DM University of - - 2014
Generalized linear and nonlinear mixed models (GMMMs and NLMMs) are commonly used to represent non-Gaussian or nonlinear longitudinal or clustered data. A common assumption is that the random effects are Gaussian. However, this assumption may be unrealistic in some applications, and misspecification of the random effects density may lead to ...
Gergs André A Department of Environmental, Social and Spatial Change, Roskilde University, Roskilde, - - 2014
Population size is often regulated by negative feedback between population density and individual fitness. At high population densities, animals run into double trouble: they might concurrently suffer from overexploitation of resources and also from negative interference among individuals regardless of resource availability, referred to as crowding. Animals are able to ...
Luo Taibo T 0000-0002-2817-8746 Business School, Sichuan University, Chengdu 610065, - - 2014
This paper investigates semi-online scheduling problems on two parallel machines under a grade of service (GoS) provision subject to minimize the makespan. We consider three different semi-online versions with knowing the total processing time of the jobs with higher GoS level, knowing the total processing time of the jobs with ...
Wasserberg Gideon G Biology Department, University of North Carolina at Greensboro, Greensboro, North Carolina, United States of - - 2014
Oviposition site selection by gravid females is an important determinant of the distribution, abundance, and dynamics of dipteran hematophagous insects. The presence of conspecific immature stages in a potential oviposition site could, on the one hand, indicate the suitability of that site but on the other hand could indicate the ...
- - 2014
[This corrects the article DOI: 10.1371/journal.pone.0079736.].
Halasa Tariq T Section of Epidemiology, The National Veterinary Institutes, Technical University of Denmark, Copenhagen, - - 2014
Two widely used simulation models of foot-and-mouth disease (FMD) were used in order to compare the models' predictions in term of disease spread, consequence, and the ranking of the applied control strategies, and to discuss the effect of the way disease spread is modeled on the predicted outcomes of each ...
Schwarzmann Günter G LIMES, Membrane Biology & Lipid Biochemistry Unit, c/o Kekulé-Institut für Organische Chemie und Biochemie, Universität Bonn, Gerhard-Domagk-Str. 1, D-53121 Bonn, - - 2013
The unraveling of sphingolipid metabolism and function in the last 40years relied on the extensive study of inherited human disease and specifically-tailored mouse models. However, only few of the achievements made so far would have been possible without chemical biology tools, such as fluorescent and/or radio-labeled and other artificial substrates, ...
1 2 3 4 5 6 7 8 9 10 >