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Zhang Danjie D Department of Statistics, University of Connecticut, Storrs, NC, 06269, - - 2014
Joint models for longitudinal and survival data now have a long history of being used in clinical trials or other studies in which the goal is to assess a treatment effect while accounting for longitudinal assessments such as patient-reported outcomes or tumor response. Compared to using survival data alone, the ...
Stewart Fiona - - 2014
Systematic reviews often investigate the effectiveness of interventions for one sex. However, identifying interventions with data presented according to the sex of study participants can be challenging due to suboptimal indexing in bibliographic databases and poor reporting in titles and abstracts. The purposes of this study were to develop a ...
Minbashian Amirali - - 2014
Previous research on within-person variability in performance has largely examined short-term fluctuations and long-term changes in performance separately. The present study proposes a model-based on the cognitive-affective personality system meta-theory (Mischel & Shoda, 1995)-that integrates short-term and long-term performance variability within the 1 framework. Key propositions of the model include ...
Wang Dashun D IBM Thomas J. Watson Research Center, Yorktown Heights, NY 10598, - - 2014
Wang, Mei, and Hicks claim that they observed large mean prediction errors when using our model. We find that their claims are a simple consequence of overfitting, which can be avoided by standard regularization methods. Here, we show that our model provides an effective means to identify papers that may ...
Wang Jian J Center for R&D Monitoring (ECOOM) and Department of Managerial Economics, Strategy and Innovation, University of Leuven, Waaistraat 6, Bus 3536, 3000 Leuven, Belgium. Institute for Research Information and Quality Assurance (iFQ), Schuetzenstrasse 6a, 10117 Berlin, Germany. - - 2014
Wang et al. (Reports, 4 October 2013, p. 127) claimed high prediction power for their model of citation dynamics. We replicate their analysis but find discouraging results: 14.75% papers are estimated with unreasonably large μ (>5) and λ (>10) and correspondingly enormous prediction errors. The prediction power is even worse ...
Clark Geoffrey R GR Archaeology and Natural History, College of Asia and the Pacific, Australian National University, Canberra, ACT 0200, Australia; - - 2014
Tonga was unique in the prehistoric Pacific for developing a maritime state that integrated the archipelago under a centralized authority and for undertaking long-distance economic and political exchanges in the second millennium A.D. To establish the extent of Tonga's maritime polity, we geochemically analyzed stone tools excavated from the central ...
Kurnianto Sofyan S Institute for the Study of Earth, Oceans and Space and Department of Earth Sciences, University of New Hampshire, Morse Hall 8, College Road, NH 03824, Durham, USA; Center for International Forestry Research, Jalan CIFOR, 16115, Situ Gede, Bogor, Indonesia; Department of Fisheries and Wildlife, Oregon State University, 97331, Corvallis, OR, - - 2014
Tropical peatlands cover an estimated 440,000 km(2) (~10% of global peatland area) and are significant in the global carbon cycle by storing about 40 - 90 Gt C in peat. Over the past several decades, tropical peatlands have experienced high rates of deforestation and conversion, which is often associated with ...
Salim Agus A La Trobe University, Melbourne, Victoria 3086, - - 2014
The significant investment in measuring biomarkers has prompted investigators to improve cost-efficiency by sub-sampling in non-standard study designs. For example, investigators studying prognosis may assume that any differences in biomarkers are likely to be most apparent in an extreme sample of the earliest deaths and the longest-surviving controls. Simple logistic ...
Jiao Shengwu S 1 College of Nature Conservation, Beijing Forestry University, Beijing 100-083, - - 2014
Avian nest-site selection is an important research and management subject. The hooded crane (Grus monacha) is a vulnerable (VU) species according to the IUCN Red List. Here, we present the first long-term Chinese legacy nest data for this species (1993-2010) with publicly available metadata. Further, we provide the first study ...
Jayawardana Kaushala K School of Mathematics & Statistics, The University of Sydney, Sydney, NSW, - - 2014
In patients with metastatic melanoma, the identification and validation of accurate prognostic biomarkers will assist rational treatment planning. Studies based on '-omics' technologies have focussed on a single high-throughput data type such as gene or microRNA transcripts. Occasionally, these features have been evaluated in conjunction with limited clinico-pathologic data. With ...
Cai Weiran - - 2014
We propose a new memristive model for the neuronal synapse based on the spike-timing-dependent plasticity (STDP) protocol, considering both long-term and short-term plasticity in the synapse. Higher-order behavior is modeled by a memristor with adaptive thresholds, which realizes the well-established suppression principle of Froemke. We assume a mechanism of variable ...
Conway Sadie S The University of Texas School of Public Health, Houston, Texas, - - 2014
To operationalize a definition of long working hours that overcomes limitations of existing heterogeneous definitions and to examine the temporal trends of long working hours across worker characteristics in the US. We examined 25 years (1985-2010) of repeated working hour measures from a representative sample of workers in the US ...
Kromhout Hans H Utrecht University, Utrecht, The - - 2014
Recent analyses of long-term trends in respirable dust and quartz concentrations from the long term monitoring program of the European Industrial Minerals Association (IMA-Europe) Dust Monitoring Program (covering the years 2000-2013) showed striking downward temporal trends in exposure which came to a halt at around the year 2009. Careful analyses ...
Laurance William F - - 2014
Lianas (climbing woody vines) are important structural parasites of tropical trees and may be increasing in abundance in response to global-change drivers. We assessed long-term (-14-year) changes in liana abundance and forest dynamics within 36 1-ha permanent plots spanning -600 km2 of undisturbed rainforest in central Amazonia. Within each plot, ...
Ruiz Daniel - - 2014
Multi-model ensembles could overcome challenges resulting from uncertainties in models' initial conditions, parameterization and structural imperfections. They could also quantify in a probabilistic way uncertainties in future climatic conditions and their impacts. A four-malaria-model ensemble was implemented to assess the impact of long-term changes in climatic conditions on Plasmodium falciparum ...
Imholt Christian C Julius Kühn-Institute, Federal Research Centre for Cultivated Plants, Institute for Plant Protection in Horticulture and Forestry, Vertebrate Research, Toppheideweg 88, 48161, Muenster, - - 2014
Central European outbreak populations of the bank vole (Myodes glareolus Schreber) are known to cause damage in forestry and to transmit the most common type of Hantavirus (Puumala virus, PUUV) to humans. A sound estimation of potential effects of future climate scenarios on population dynamics is prerequisite for long-term management ...
Kim Mi-Ok MO Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, U.S.A.; Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, - - 2014
Delay in the outcome variable is challenging for outcome-adaptive randomization, as it creates a lag between the number of subjects accrued and the information known at the time of the analysis. Motivated by a real-life pediatric ulcerative colitis trial, we consider a case where a short-term predictor is available for ...
Milenkaya O O Department of Biological Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061; 2Australian Wildlife Conservancy, Mornington Wildlife Sanctuary, Derby, Australia; and Research Institute for Environment and Livelihoods, Charles Darwin University, Casuarina, - - 2014
Abstract It is common in evolutionary ecology to interpret body-condition indices as indicators of individual quality, but this hypothesized relationship has been questioned and remains poorly validated. Here, we test one of the fundamental predictions of this condition-quality hypothesis, that relative-condition indices are repeatable within individuals, that is, that the ...
Yan Huadong H Department of Infectious Diseases, Ningbo No. 2 Hospital, Ningbo 315010, - - 2014
A considerable proportion of chronic hepatitis B (CHB) or hepatitis B virus (HBV)-related cirrhotic patients develop acute-on-chronic liver failure (ACLF) with high short-term mortality. It remains difficult to accurately predict short-term prognosis in ACLF patients. The aim of the study is to develop a new prognostic model by assessing new ...
Rooijakkers Michael J MJ Faculty of Electrical Engineering, University of Technology Eindhoven, 5612 AZ Eindhoven, The - - 2014
Monitoring the progression of maternal uterine activity provides important prognostic information during pregnancy and parturition. Currently used methods for intrauterine pressure (IUP) measurement are unsuitable for long-term observation of uterine activity. The abdominally measured electrohysterogram (EHG) provides a non-invasive alternative to the existing methods for long-term ambulatory uterine contraction monitoring. ...
Longin C Friedrich H CF State Plant Breeding Institute, University of Hohenheim, 70599, Stuttgart, Germany, - - 2014
The predicted future yield potential of hybrids was competitive with lines in the near future, but on a long term the competitiveness of hybrids depends on a number of factors. The change from line to hybrid breeding in autogamous crops is a recent controversial discussion among scientists and breeders. Our ...
Yuan Mengdie - - 2014
Abstract The proportional odds model is commonly used in the analysis of failure time data. The assumption of constant odds ratios over time in the proportional odds model, however, can be violated in some applications. Motivated by a genetic study with breast cancer patients, we propose a novel semiparametric odds ...
Cuthill Innes C IC School of Biological Sciences, University of Bristol, Woodland Road, Bristol BS8 1UG, UK. Electronic address: - - 2014
Mimicry has long provided some of the most persuasive examples of the power of natural selection. However, some mimics are quite poor. A new study shows that mechanisms by which animals learn might explain how imperfect mimics survive.
Porter Theodore M TM Department of History, University of California, Los Angeles, United States. Electronic address: - - 2014
For more than a century, geneticists have consistently identified the origins of their science with Gregor Mendel's experiments on peas. Mendelism, they have said, demonstrated at long last that biological inheritance was not, as had so often been supposed, "blending," but particulate. Many historians of biology continue to interpret the ...
Melo D R DR *Lovelace Respiratory Research Institute, Albuquerque, NM; †State University of Rio de Janeiro, Brazil; ‡Oak Ridge National Laboratory, TN; §Los Alamos National Laboratory, Los Alamos, - - 2014
Prussian blue (PB) is an efficient drug for enhancing cesium elimination from the body. Literature data on the efficacy of PB treatment in dosages that vary from 1-10 g d was reviewed. Cesium biokinetics was simulated using a detailed systemic biokinetic model. The same model was used to simulate the ...
Losiak Anna A 1 Institute of Geological Sciences , Polish Academy of Sciences, Wroclaw, Poland - - 2014
Abstract MARS2013 was an integrated Mars analog field simulation in eastern Morocco performed by the Austrian Space Forum between February 1 and 28, 2013. The purpose of this paper is to discuss the system of data processing and utilization adopted by the Remote Science Support (RSS) team during this mission. ...
Webster Timothy H TH Department of Anthropology, Miami University, 120 Upham Hall, 100 Bishop Circle, Oxford, OH 45056-1879, USA; Division of Biological Anthropology, Department of Archaeology and Anthropology, University of Cambridge, Fitzwilliam Street, Cambridge CB2 IQH, UK; Department of Anthropology, Yale University, 10 Sachem Street, New Haven, CT 06511-3707, USA. Electronic address: - - 2014
Chimpanzee (Pan troglodytes) insectivory across Africa is ubiquitous. Insects provide a significant nutritional payoff and may be important for chimpanzees in dry, open habitats with narrow diets. We tested this hypothesis at Semliki, Uganda, a long-term dry study site. We evaluated prospects for insectivory by measuring insect abundance along de ...
Liu Jin J Division of Epidemiology and Biostatistics, UIC School of Public Health, Chicago, Illinois, - - 2014
In cancer research, profiling studies have been extensively conducted, searching for genes/SNPs associated with prognosis. Cancer is diverse. Examining the similarity and difference in the genetic basis of multiple subtypes of the same cancer can lead to a better understanding of their connections and distinctions. Classic meta-analysis methods analyze each ...
Vanwonterghem Inka I 1] Advanced Water Management Centre (AWMC), University of Queensland, St Lucia, Queensland, Australia [2] Australian Centre for Ecogenomics (ACE), School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland, - - 2014
A replicate long-term experiment was conducted using anaerobic digestion (AD) as a model process to determine the relative role of niche and neutral theory on microbial community assembly, and to link community dynamics to system performance. AD is performed by a complex network of microorganisms and process stability relies entirely ...
Hansen M F MF Track Analysis Systems Ltd, Napier House, Meadow Grove, Bristol BS11 9PJ, - - 2014
Radon measurements over a short-term period of a few days have proven a popular choice with the general public, despite the issue that the radon concentration can vary significantly over time and longer periods of integration are recommended. Performing short-term radon measurements using a Poly Allyl Diglycol Carbonate (PADC) detector ...
Kunz Cornelia Ursula CU a Warwick Medical School , The University of Warwick , Coventry , - - 2014
In an adaptive seamless phase II/III clinical trial interim analysis data are used for treatment selection, enabling resources to be focussed on comparison of more effective treatment(s) with a control. In this paper we compare two methods recently proposed to enable use of short-term endpoint data for decision-making at the ...
Fox R R Cancer Research UK Clinical Trials Unit, School of Cancer Sciences, University of Birmingham, Birmingham B15 2TT, - - 2014
Background:The Japanese 'BALAD' model offers the first objective, biomarker-based, tool for assessment of prognosis in hepatocellular carcinoma, but relies on dichotomisation of the constituent data, has not been externally validated, and cannot be applied to the individual patients.Methods:In this Japanese/UK collaboration, we replicated the original BALAD model on a UK ...
Bliss-Moreau Eliza E Brain, Mind, and Behavior Unit, California National Primate Research Center, University of California, Davis, Davis, CA 95616. eblissmoreau@ucdavis.edu - - 2014
Building upon Huang & Bargh's (H&B's) theory, we propose a complementary view that goal formation and selection are both supported by affect. We suggest that goals may form when affect "tags" discrete behaviors and their outcomes. Further, we propose that goal-associated affect may help guide selection between competing goals, for ...
Chicheportiche Rémy R Chaire de finance quantitative, École Centrale Paris, 92 295 Châtenay-Malabry, - - 2014
We review ideas on temporal dependencies and recurrences in discrete time series from several areas of natural and social sciences. We revisit existing studies and redefine the relevant observables in the language of copulas (joint laws of the ranks). We propose that copulas provide an appropriate mathematical framework to study ...
Løvik Amund N - - 2014
Aluminum recycling currently occurs in a cascading fashion, where some alloys, used in a limited number of applications, absorb most of the end-of-life scrap. An expected increase in scrap supply in coming decades necessitates restructuring of the aluminum cycle to open up new recycling paths for alloys and avoid a ...
Donohue Michael C MC Department of Family and Preventive Medicine, Division of Biostatistics and Bioinformatics, University of California San Diego, La Jolla, CA, USA. Electronic address: - - 2014
Diseases that progress slowly are often studied by observing cohorts at different stages of disease for short periods of time. The Alzheimer's Disease Neuroimaging Initiative (ADNI) follows elders with various degrees of cognitive impairment, from normal to impaired. The study includes a rich panel of novel cognitive tests, biomarkers, and ...
Lee Duncan D 1School of Mathematics and Statistics, University of Glasgow, Glasgow, - - 2014
Estimating the long-term health impact of air pollution using an ecological spatio-temporal study design is a challenging task, due to the presence of residual spatio-temporal autocorrelation in the health counts after adjusting for the covariate effects. This autocorrelation is commonly modelled by a set of random effects represented by a ...
Lim Lily S H LS Division of Rheumatology, Department of Pediatrics, The Hospital for Sick Children, Hospital for Sick Children Research Institute, University of Toronto, Toronto, Canada; Departments of Pediatrics, Medicine, Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, - - 2014
Objective: Prognosis studies examine outcomes and/or seek to identify predictors or factors associated with outcomes. Many prognostic factors have been identified in Systemic Lupus Erythematosus (SLE) but few have been consistently found across studies. We hypothesized that this is due to lack of rigor of study designs. This study aimed ...
Kleinhappel T K TK School of Life Sciences, University of Lincoln, Lincoln, LN2 2LG, - - 2014
This paper describes and evaluates a flexible, non-invasive tagging system for the automated identification and long-term monitoring of individual three-spined sticklebacks Gasterosteus aculeatus. The system is based on barcoded tags, which can be reliably and robustly detected and decoded to provide information on an individual's identity and location. Because large ...
Salmi L Rachid LR University of Bordeaux, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Bordeaux, France; INSERM, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Bordeaux, France; CHU de Bordeaux, Pole de sante publique, Service d'information medicale, Bordeaux, France. Electronic address: - - 2014
Prognostic studies of mild traumatic brain injury (MTBI) can serve many purposes. First, they are used to describe paths and outcomes of patients with MTBI. Second, they provide information on which characteristics are associated with the occurrence of outcomes. Third, they provide insight into the causation of poor or favorable ...
Battiston Federico F School of Mathematical Sciences, Queen Mary University of London, London E1 4NS, United - - 2014
Many real-world complex systems consist of a set of elementary units connected by relationships of different kinds. All such systems are better described in terms of multiplex networks, where the links at each layer represent a different type of interaction between the same set of nodes rather than in terms ...
Lavine Michael - - 2014
Murtaugh and I agree on an important point: abandon accept/reject declarations. That alone will go a long way to improving statistical practice. (2) Don't confuse P values or deltaAIC with binary declarations. An argument against one is not necessarily an argument against the other. (3) Be careful interpreting a P ...
Brown Jeremy M JM Department of Biological Sciences, Louisiana State University, Baton Rouge, LA, - - 2014
Evolutionary inference is now an overwhelmingly model-based endeavor, allowing biological hypotheses to be tested in formal statistical frameworks. Stochastic models are employed to describe a broad range of evolutionary processes (e.g., coalescence within populations, long-term trends in diversification rates, and the evolution of both genomes and phenotypic traits). The shift ...
Kiranyaz Serkan S Turker Ince, Morteza Zabihi and Dilek Ince. Electronic address: - - 2014
This paper presents a novel systematic approach for patient-specific classification of long-term Electroencephalography (EEG). The goal is to extract the seizure sections with a high accuracy to ease the Neurologist's burden of inspecting such long-term EEG data. We aim to achieve this using the minimum feedback from the Neurologist. To ...
Wong Yin Cheong YC School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Room 801C, Lo Kwee-Seong Integrated Biomedical Sciences Building, Shatin, New Territories, Hong - - 2014
To investigate the pharmacokinetic differences between the common nasal delivery models. In three different rat models [long-term anesthetized (with nasal surgery), short-term anesthetized (without nasal surgery) and conscious models], tacrine and loxapine were administered via nasal, intravenous and oral routes, and the plasma pharmacokinetics were compared among different models. Systemic ...
D'Agostino Maria Antonietta MA Department of Rheumatology, AP-HP Ambroise Paré Hospital, Université Versailles Saint Quentin en Yvelines, Boulogne-Billancourt, France. - - 2014
Musculoskeletal ultrasound is an evolving technique widely used in rheumatology thanks to the numerous advances and the improved work on standardisation. This article deals with the new developments in terms of technology and validation.
Staffieri Claudia C Otolaryngology Section, Department of Neurosciences, Treviso Branch, University of Padova, Padua, - - 2014
Deep neck infections (DNI) spread along fascial planes and involve neck spaces. Very few studies have investigated potentially prognostic factors using multivariate statistical models. Our aim was to analyze 282 consecutive cases of DNI using multivariate (logistic) statistical models to identify independent significant factors influencing prognosis in terms of complications ...
Winskill Peter - - 2014
Control of the world's most important vector-borne viral disease, dengue, is a high priority. A lack of vaccines or effective vector control methods means that novel solutions to disease control are essential. The release of male insects carrying a dominant lethal (RIDL) is one such approach that could be employed ...
Ghali Bassma - - 2014
Background: While there is growing interest in clinical and industrial applications of handwriting grip kinetics, the stability of these forces over time is not well-understood at present. In this study, we investigated the short- and long-term intra- and inter-participant variability of grip kinetics associated with adult signature writing. Method of ...
Granet Gérard - - 2014
The B-spline modal method (BMM) as applied to lamellar gratings analysis is revisited, and a new implementation is presented. The main difference with our previous work is that we now take into account discontinuities by putting a spline with a degenerate knot on them. Our new approach is compared with ...
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