Search Results
Results 1 - 50 of 1678
1 2 3 4 5 6 7 8 9 10 >
Melo D R DR *Lovelace Respiratory Research Institute, Albuquerque, NM; †State University of Rio de Janeiro, Brazil; ‡Oak Ridge National Laboratory, TN; §Los Alamos National Laboratory, Los Alamos, - - 2014
Prussian blue (PB) is an efficient drug for enhancing cesium elimination from the body. Literature data on the efficacy of PB treatment in dosages that vary from 1-10 g d was reviewed. Cesium biokinetics was simulated using a detailed systemic biokinetic model. The same model was used to simulate the ...
Vanwonterghem Inka I 1] Advanced Water Management Centre (AWMC), University of Queensland, St Lucia, Queensland, Australia [2] Australian Centre for Ecogenomics (ACE), School of Chemistry and Molecular Biosciences, University of Queensland, St Lucia, Queensland, - - 2014
A replicate long-term experiment was conducted using anaerobic digestion (AD) as a model process to determine the relative role of niche and neutral theory on microbial community assembly, and to link community dynamics to system performance. AD is performed by a complex network of microorganisms and process stability relies entirely ...
Kunz Cornelia Ursula CU a Warwick Medical School , The University of Warwick , Coventry , - - 2014
In an adaptive seamless phase II/III clinical trial interim analysis data are used for treatment selection, enabling resources to be focussed on comparison of more effective treatment(s) with a control. In this paper we compare two methods recently proposed to enable use of short-term endpoint data for decision-making at the ...
Fox R R Cancer Research UK Clinical Trials Unit, School of Cancer Sciences, University of Birmingham, Birmingham B15 2TT, - - 2014
Background:The Japanese 'BALAD' model offers the first objective, biomarker-based, tool for assessment of prognosis in hepatocellular carcinoma, but relies on dichotomisation of the constituent data, has not been externally validated, and cannot be applied to the individual patients.Methods:In this Japanese/UK collaboration, we replicated the original BALAD model on a UK ...
Løvik Amund N - - 2014
Aluminum recycling currently occurs in a cascading fashion, where some alloys, used in a limited number of applications, absorb most of the end-of-life scrap. An expected increase in scrap supply in coming decades necessitates restructuring of the aluminum cycle to open up new recycling paths for alloys and avoid a ...
Donohue Michael C MC Department of Family and Preventive Medicine, Division of Biostatistics and Bioinformatics, University of California San Diego, La Jolla, CA, USA. Electronic address: - - 2014
Diseases that progress slowly are often studied by observing cohorts at different stages of disease for short periods of time. The Alzheimer's Disease Neuroimaging Initiative (ADNI) follows elders with various degrees of cognitive impairment, from normal to impaired. The study includes a rich panel of novel cognitive tests, biomarkers, and ...
Lee Duncan D 1School of Mathematics and Statistics, University of Glasgow, Glasgow, - - 2014
Estimating the long-term health impact of air pollution using an ecological spatio-temporal study design is a challenging task, due to the presence of residual spatio-temporal autocorrelation in the health counts after adjusting for the covariate effects. This autocorrelation is commonly modelled by a set of random effects represented by a ...
Lim Lily S H LS Division of Rheumatology, Department of Pediatrics, The Hospital for Sick Children, Hospital for Sick Children Research Institute, University of Toronto, Toronto, Canada; Departments of Pediatrics, Medicine, Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, - - 2014
Objective: Prognosis studies examine outcomes and/or seek to identify predictors or factors associated with outcomes. Many prognostic factors have been identified in Systemic Lupus Erythematosus (SLE) but few have been consistently found across studies. We hypothesized that this is due to lack of rigor of study designs. This study aimed ...
Kleinhappel T K TK School of Life Sciences, University of Lincoln, Lincoln, LN2 2LG, - - 2014
This paper describes and evaluates a flexible, non-invasive tagging system for the automated identification and long-term monitoring of individual three-spined sticklebacks Gasterosteus aculeatus. The system is based on barcoded tags, which can be reliably and robustly detected and decoded to provide information on an individual's identity and location. Because large ...
Salmi L Rachid LR University of Bordeaux, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Bordeaux, France; INSERM, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique, Bordeaux, France; CHU de Bordeaux, Pole de sante publique, Service d'information medicale, Bordeaux, France. Electronic address: - - 2014
Prognostic studies of mild traumatic brain injury (MTBI) can serve many purposes. First, they are used to describe paths and outcomes of patients with MTBI. Second, they provide information on which characteristics are associated with the occurrence of outcomes. Third, they provide insight into the causation of poor or favorable ...
Battiston Federico F School of Mathematical Sciences, Queen Mary University of London, London E1 4NS, United - - 2014
Many real-world complex systems consist of a set of elementary units connected by relationships of different kinds. All such systems are better described in terms of multiplex networks, where the links at each layer represent a different type of interaction between the same set of nodes rather than in terms ...
Brown Jeremy M JM Department of Biological Sciences, Louisiana State University, Baton Rouge, LA, - - 2014
Evolutionary inference is now an overwhelmingly model-based endeavor, allowing biological hypotheses to be tested in formal statistical frameworks. Stochastic models are employed to describe a broad range of evolutionary processes (e.g., coalescence within populations, long-term trends in diversification rates, and the evolution of both genomes and phenotypic traits). The shift ...
Kiranyaz Serkan S Turker Ince, Morteza Zabihi and Dilek Ince. Electronic address: - - 2014
This paper presents a novel systematic approach for patient-specific classification of long-term Electroencephalography (EEG). The goal is to extract the seizure sections with a high accuracy to ease the Neurologist's burden of inspecting such long-term EEG data. We aim to achieve this using the minimum feedback from the Neurologist. To ...
Wong Yin Cheong YC School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Room 801C, Lo Kwee-Seong Integrated Biomedical Sciences Building, Shatin, New Territories, Hong - - 2014
To investigate the pharmacokinetic differences between the common nasal delivery models. In three different rat models [long-term anesthetized (with nasal surgery), short-term anesthetized (without nasal surgery) and conscious models], tacrine and loxapine were administered via nasal, intravenous and oral routes, and the plasma pharmacokinetics were compared among different models. Systemic ...
D'Agostino Maria Antonietta MA Department of Rheumatology, AP-HP Ambroise Paré Hospital, Université Versailles Saint Quentin en Yvelines, Boulogne-Billancourt, France. - - 2014
Musculoskeletal ultrasound is an evolving technique widely used in rheumatology thanks to the numerous advances and the improved work on standardisation. This article deals with the new developments in terms of technology and validation.
Staffieri Claudia C Otolaryngology Section, Department of Neurosciences, Treviso Branch, University of Padova, Padua, - - 2014
Deep neck infections (DNI) spread along fascial planes and involve neck spaces. Very few studies have investigated potentially prognostic factors using multivariate statistical models. Our aim was to analyze 282 consecutive cases of DNI using multivariate (logistic) statistical models to identify independent significant factors influencing prognosis in terms of complications ...
Winskill Peter - - 2014
Control of the world's most important vector-borne viral disease, dengue, is a high priority. A lack of vaccines or effective vector control methods means that novel solutions to disease control are essential. The release of male insects carrying a dominant lethal (RIDL) is one such approach that could be employed ...
Ghali Bassma - - 2014
Background: While there is growing interest in clinical and industrial applications of handwriting grip kinetics, the stability of these forces over time is not well-understood at present. In this study, we investigated the short- and long-term intra- and inter-participant variability of grip kinetics associated with adult signature writing. Method of ...
Granet Gérard - - 2014
The B-spline modal method (BMM) as applied to lamellar gratings analysis is revisited, and a new implementation is presented. The main difference with our previous work is that we now take into account discontinuities by putting a spline with a degenerate knot on them. Our new approach is compared with ...
Robidart Julie C JC 1] Department of Ocean Sciences, University of California Santa Cruz, Santa Cruz, CA, USA [2] Monterey Bay Aquarium Research Institute, Moss Landing, CA, USA [3] Center for Microbial Oceanography: Research and Education, University of Hawaii, Honolulu, HI, - - 2014
Nitrogen-fixing microorganisms (diazotrophs) are keystone species that reduce atmospheric dinitrogen (N2) gas to fixed nitrogen (N), thereby accounting for much of N-based new production annually in the oligotrophic North Pacific. However, current approaches to study N2 fixation provide relatively limited spatiotemporal sampling resolution; hence, little is known about the ecological ...
Dons Evi E VITO - Flemish Institute for Technological Research, Mol, Belgium; IMOB - Transportation Research Institute, Hasselt University, - - 2014
In the HEAPS (Health Effects of Air Pollution in Antwerp Schools) study the importance of traffic-related air pollution on the school and home location on children's health was assessed. 130 children (aged 6 to 12) from two schools participated in a biomonitoring study measuring oxidative stress, inflammation and cardiovascular markers. ...
Fernandez de Canete J J Dpt. de Ing. de Sistemas y Automatica, E.T.S.I. Industriales, Campus de Teatinos, 29071 Malaga, Spain. Electronic address: - - 2014
A mathematical model that provides an overall description of both the short- and long-term mechanisms of arterial pressure regulation is presented. Short-term control is exerted through the baroreceptor reflex while renal elimination plays a role in long-term control. Both mechanisms operate in an integrated way over the compartmental model of ...
Sirkka Marianne M Department of Occupational Therapy, Sunderby Hospital , Luleå, Norrbotten County Council , - - 2014
Abstract Objective: The aim of this qualitative descriptive study was to describe occupational therapists' experiences of participating in long-term improvement work based on the Occupational Therapy Intervention Process Model. Method. Data were collected by focus groups interviewed on two occasions (2006 and 2011). Nineteen occupational therapists participated on each occasion. ...
Joniau Steven S Department of Urology, University Hospitals, Leuven, Belgium. Electronic address: - - 2014
High-risk prostate cancer (PCa) is an extremely heterogeneous disease. A clear definition of prognostic subgroups is mandatory. To develop a pretreatment prognostic model for PCa-specific survival (PCSS) in high-risk PCa based on combinations of unfavorable risk factors. We conducted a retrospective multicenter cohort study including 1360 consecutive patients with high-risk ...
Mougin Fleur F ISPED, Université de Bordeaux 2, Bordeaux, - - 2014
This work focuses on multiply-related Unified Medical Language System (UMLS) concepts, that is, concepts associated through multiple relations. The relations involved in such situations are audited to determine whether they are provided by source vocabularies or result from the integration of these vocabularies within the UMLS. We study the compatibility ...
Burgdorf Walter H C WH Department of Dermatology, Ludwig Maximilian University, Munich, - - 2014
Eosinophilic apoptotic (necrotic) keratinocytes in the lower epidermis and at the dermoepidermal junction are a feature of many interface dermatoses but are most reliably found in lichen planus. These structures are universally known as Civatte bodies. Nonetheless, they were first described by Raymond Sabouraud in 1912. Even after Achille Civatte ...
Giavi Simone S Community Ecology, Swiss Federal Research Institute WSL, Bellinzona, Ticino, - - 2014
Migration is adaptive if survival benefits are larger than costs of residency. Many aspects of bat migration ecology such as migratory costs, stopover site use and fidelity are largely unknown. Since many migrating bats are endangered, such information is urgently needed to promote conservation. We selected the migrating Leisler's bat ...
McCoy S J SJ Department of Ecology and Evolution, The University of Chicago, Chicago, IL, 60637, - - 2014
As the ocean environment changes over time, a paucity of long-term data sets and historical comparisons limits the exploration of community dynamics over time in natural systems. Here, we used a long-term experimental data set to present evidence for a reversal of competitive dominance within a group of crustose coralline ...
Maddux Nathaniel R NR Department of Pharmaceutical Chemistry, Macromolecule and Vaccine Stabilization Center, University of Kansas, Lawrence, Kansas; Department of Physics and Astronomy, University of Kansas, Lawrence, - - 2014
Changes in the measurements of a macromolecular biopharmaceutical's physical form are often used to predict changes in the drug's long-term stability. These can in turn be used as important markers of changes to a drug's efficacy and safety. Such stability estimates traditionally require human judgment and are frequently tentative. We ...
Valinia Salar S Swedish University of Agricultural Sciences, Department of Aquatic sciences and Assessment, Lennart Hjelms väg 9, Box SE- 7050, Uppsala, - - 2014
Quantifying the effects of human activity on the natural environment is dependent on credible estimates of reference conditions to define the state of the environment before the onset of adverse human impacts. In Europe, emission controls that aimed at restoring ecological status were based on hind casts from process-based models ...
Bi Hongsheng H Chesapeake Biological Laboratory, University of Maryland Center for Environmental Science, Solomons, Maryland, United States of - - 2014
The abundance of the subarctic copepod, Calanus finmarchicus, and temperate, shelf copepod, Centropages typicus, was estimated from samples collected bi-monthly over the Northeast U.S. continental shelf (NEUS) from 1977-2010. Latitudinal variation in long term trends and seasonal patterns for the two copepod species were examined for four sub-regions: the Gulf ...
Mecocci Alessandro A Department of Information Engineering and Mathematical Sciences, University of Siena, Via Roma 56, Siena 53100, Italy. - - 2014
This paper describes a wireless sensor network (WSN) used to monitor the health state of architectural heritage in real-time. The WSN has been deployed and tested on the "Rognosa" tower in the medieval village of San Gimignano, Tuscany, Italy. This technology, being non-invasive, mimetic, and long lasting, is particularly well ...
Xie Shengkun S 0000-0002-9533-2096 Department of Global Management Studies, Ted Rogers School of Management Studies, Ryerson University, 350 Victoria Street, Toronto, ON, Canada M5B - - 2014
Classification of electroencephalography (EEG) is the most useful diagnostic and monitoring procedure for epilepsy study. A reliable algorithm that can be easily implemented is the key to this procedure. In this paper a novel signal feature extraction method based on dynamic principal component analysis and nonoverlapping moving window is proposed. ...
Fuentes-Reinés Juan M JM Universidad del Magdalena, Grupo de Investigación en Limnología. A.A 731 Santa Marta, Magdalena, - - 2014
Plankton samples from Laguna Navio Quebrado, La Guajira, northern Colombia, yielded male and female specimens of an harpacticoid copepod that was first identified as the widely distributed species Nitokra affinis Gurney, 1927 for which at least four subspecies have been described from different geographic areas. A more detailed examination of ...
Cocking Matthew I - - 2014
We studied vegetation composition and structure in a mixed conifer-oak ecosystem across a range of fire severity 10 years following wildfire. Sample plots centered on focal California black oaks (Quercus kelloggii) were established to evaluate oak and neighboring tree and shrub recovery across a gradient of fire severity in the ...
Krieg Daniel D Frankfurt Institute for Advanced Studies, Goethe University Frankfurt, - - 2014
Long-term synaptic plasticity is fundamental to learning and network function. It has been studied under various induction protocols and depends on firing rates, membrane voltage, and precise timing of action potentials. These protocols show different facets of a common underlying mechanism but they are mostly modeled as distinct phenomena. Here, ...
Jacquemin Stephen J SJ Department of Biological Sciences, Wright State University - Lake Campus, Celina, Ohio, United States of - - 2014
We combine evolutionary biology and community ecology to test whether two species traits, body size and geographic range, explain long term variation in local scale freshwater stream fish assemblages. Body size and geographic range are expected to influence several aspects of fish ecology, via relationships with niche breadth, dispersal, and ...
Nudds Robert L RL Faculty of Life Sciences, University of Manchester, Manchester, United - - 2014
Recently it was proposed that the primary feathers of Archaeopteryx lithographica (HMN1880) were overlaid by long covert feathers, and that a multilayered feathered wing was a feature of early fossils with feathered forelimbs. The proposed long covert feathers of Archaeopteryx were previously interpreted as dorsally displaced remiges or a second ...
Ammunét Tea T Department of Ecology, Swedish University of Agricultural Sciences, Box 7044, SE-75007, Uppsala, Sweden; Section of Ecology, Department of Biology, University of Turku, FI-20014 Turku, Finland. Electronic address: - - 2013
Invasive species can have profound effects on a resident community via indirect interactions among community members. While long periodic cycles in population dynamics can make the experimental observation of the indirect effects difficult, modelling the possible effects on an evolutionary time scale may provide the much needed information on the ...
Verma Vibha V Griffith School of Engineering, Griffith University, Nathan Campus, Brisbane, Queensland 4111, - - 2013
A model based on the concept of reduction in life expectancy (RLE model) as a result of long term exposure to toxicant has been developed which has normal life expectancy (NLT) as a fixed limiting point for a species. The model is based on the equation (LC50 = a ln(LT50) + ...
Kattwinkel Mira M Department of System-Ecotoxicology, Helmholtz Centre for Environmental Research - UFZ, 04318, Leipzig, Germany; Department of System Analysis, Integrated Assessment and Modelling, Eawag: Swiss Federal Institute of Aquatic Science and Technology, 8600, Dübendorf, - - 2013
Recent empirical studies have revealed the importance of species competition for the effects of toxicants on populations. In the present study, we applied a generic individual-based simulation model (IBM) of two competing species to analyze the consequences of interspecific competition for population dynamics under pulsed contamination. The results indicated that ...
García-Mozo H H Department of Botany, Ecology and Plant Physiology, Agrifood Campus of International Excellence (CeiA3), University of Córdoba, Córdoba, Spain. Electronic address: - - 2013
Analysis of long-term airborne pollen counts makes it possible not only to chart pollen-season trends but also to track changing patterns in flowering phenology. Changes in higher plant response over a long interval are considered among the most valuable bioindicators of climate change impact. Phenological-trend models can also provide information ...
Bonachela Juan A JA Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, 08544, USA. Electronic address: - - 2013
Marine viruses shape the structure of the microbial community. They are, thus, a key determinant of the most important biogeochemical cycles in the planet. Therefore, a correct description of the ecological and evolutionary behavior of these viruses is essential to make reliable predictions about their role in marine ecosystems. The ...
Griffin Mark A MA The University of Western Australia, Australia. Electronic address: - - 2013
The paper outlines a systemic approach to understanding and assessing safety capability in the offshore oil and gas industry. We present a conceptual framework and assessment guide for understanding fitness-to-operate (FTO) that builds a more comprehensive picture of safety capability for regulators and operators of offshore facilities. The FTO framework ...
Lettenmeier Michael M Wuppertal Institute for Climate, Environment and Energy, Döppersberg 19, D-42103 Wuppertal, Germany; D-mat Ltd., Purokatu 34, FIN-15200 Lahti, Finland. Electronic address: - - 2013
A decent, or sufficient, lifestyle is largely considered an important objective in terms of a sustainable future. However, there can be strongly varying definitions of what a decent lifestyle means. From a social sustainability point of view, a decent lifestyle can be defined as the minimum level of consumption ensuring ...
Nielsen Jens J Research Software Development Team, Research IT Services, University College London, Torrington Place, London WC1E 6BT, United - - 2013
Ab initio kinetic Monte Carlo (KMC) simulations have been successfully applied for over two decades to elucidate the underlying physico-chemical phenomena on the surfaces of heterogeneous catalysts. These simulations necessitate detailed knowledge of the kinetics of elementary reactions constituting the reaction mechanism, and the energetics of the species participating in ...
Soler Manuel M Departamento de Zoología, Facultad de Ciencias, Universidad de Granada, Avenida Severo Ochoa s/n, E-18071, Granada, Spain; Grupo Coevolución, Unidad Asociada al CSIC, Universidad de Granada, Avenida Severo Ochoa s/n, E-18071, Granada, - - 2013
Coevolutionary theory predicts that the most common long-term outcome of the relationships between brood parasites and their hosts should be coevolutionary cycles based on a dynamic change selecting the currently least-defended host species, given that when well-defended hosts are abandoned, hosts will be selected to decrease their defences as these ...
Dayton Paul P UnityPoint Clinic, Foot and Ankle Division, Fort Dodge, IA; and Adjunct Professor, Des Moines University College of Podiatric Medicine and Surgery, Des Moines, IA. Electronic address: - - 2013
Evolution of the terminology applied to the bunion deformity has progressed in parallel with our changing understanding of the deformity itself. Along this path of progression have been multiple terms, sometimes with multiple meanings. Hallux valgus and metatarsus primus varus are 2 of the most common terms for the deformity. ...
Song James X JX 100 Tice Blvd, Woodcliff Lake, NJ 07677, USA. Electronic address: - - 2013
Illustrated is the use of a patient enrichment adaptive design in a randomized phase II trial which allows the evaluation of treatment benefits by the biomarker expression level and makes interim adjustment according to the pre-specified rules. The design was applied to an actual phase II metastatic hepatocellular carcinoma (HCC) ...
Grigorievskiy Alexander A Department of Information and Computer Science, Aalto University School of Science, FI-00076 Aalto, Finland. Electronic address: - - 2013
In this paper, an Optimally Pruned Extreme Learning Machine (OP-ELM) is applied to the problem of long-term time series prediction. Three known strategies for the long-term time series prediction i.e. Recursive, Direct and DirRec are considered in combination with OP-ELM and compared with a baseline linear least squares model and ...
1 2 3 4 5 6 7 8 9 10 >