Search Results
Results 1 - 50 of 1668
1 2 3 4 5 6 7 8 9 10 >
Jensen Mark P MP a University of Washington , Seattle , - - 2015
Abstract Evidence supports the efficacy of hypnotic treatments, but there remain many unresolved questions regarding how hypnosis produces its beneficial effects. Most theoretical models focus more or less on biological, psychological, and social factors. This scoping review summarizes the empirical findings regarding the associations between specific factors in each of ...
Banou Eirini E Department of Informatics, Ionian University, 7 Tsirigoti Square, Corfu, Greece, - - 2015
The present work aims to study extensively the literature on the phenomenon of "kinesia paradoxa" presented in Parkinson's disease patients, who generally cannot move but under certain circumstances exhibit a sudden, brief period of mobility (walking or even running). The objective of this study was to identify the mechanisms causing ...
Chow Sy-Miin SM The Pennsylvania State University, 413 Biobehavioral Health Building, University Park, PA, 16802 , USA, - - 2014
The past decade has evidenced the increased prevalence of irregularly spaced longitudinal data in social sciences. Clearly lacking, however, are modeling tools that allow researchers to fit dynamic models to irregularly spaced data, particularly data that show nonlinearity and heterogeneity in dynamical structures. We consider the issue of fitting multivariate ...
Vaz Frédéric M FM Laboratory Genetic Metabolic Disease (F0-224), Departments of Clinical Chemistry and Pediatrics, University of Amsterdam, Academic Medical Center (AMC), Amsterdam, 1105 AZ, The Netherlands, - - 2014
The technical advances in mass spectrometry, particularly the development of (ultra)-high-resolution/mass accuracy measurement capabilities in combination with refinement of soft ionization techniques, have increased the application and success of lipidomics to answer biological questions in relation to lipid metabolism. Together with other omics technologies, lipidomics has become an important tool ...
Baker Jannah - - 2014
Spatial analysis is increasingly important for identifying modifiable geographic risk factors for disease. However, spatial health data from surveys are often incomplete, ranging from missing data for only a few variables, to missing data for many variables. For spatial analyses of health outcomes, selection of an appropriate imputation method is ...
Bighamian Ramin - - 2014
In this study, we present a system identification approach to the mathematical modeling of hemodynamic responses to vasopressor-inotrope agents. We developed a hybrid model called the latency-dose-response-cardiovascular (LDC) model that incorporated (i) a low-order lumped latency model to reproduce the delay associated with the transport of vasopressor-inotrope agent and the ...
van Diepen Sean - - 2014
IntroductionIn medical and surgical intensive care units, clinical risk prediction models for readmission have been developed; however studies reporting the risks for cardiovascular intensive care unit (CVICU) readmission have been methodologically limited by small numbers of outcomes, unreported measures of calibration or discrimination, or a lack of information spanning the ...
Chen Xiang X Key Laboratory of Biomedical Information Engineering of Ministry of Education, Institute of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of - - 2014
Transient changes in cardiovascular regulatory activities are valuable for clinical monitoring and pathophysiological research. However, there is a lack of effective methods to evaluate short-term cardiovascular regulation. This study explores a photoplethysmography (PPG)-based multi-parameter analytical approach using the period, amplitude and baseline of PPG signals to quantitatively assess cardiovascular regulation ...
Zhang Zhiwei Z U.S. Food and Drug Administration, Silver Spring, USA - - 2014
A common problem in randomized clinical trials is nonignorable missingness, namely that the clinical outcome(s) of interest can be missing in a way that is not fully explained by the observed quantities. This happens when the continued participation of patients depends on the current outcome after adjusting for the observed ...
White Easton R - - 2014
Long-lived marine megavertebrates (e.g. sharks, turtles, mammals, and seabirds) are inherently vulnerable to anthropogenic mortality. Although some mathematical models have been applied successfully to manage these animals, more detailed treatments are often needed to assess potential drivers of population dynamics. In particular, factors such as age-structure, density-dependent feedbacks on reproduction, ...
Martin Adam - - 2014
BackgroundExisting reviews identify numerous studies of the relationship between urban built environment characteristics and obesity. These reviews do not generally distinguish between cross-sectional observational studies using single equation analytical techniques and other studies that may support more robust causal inferences. More advanced analytical techniques, including the use of instrumental variables ...
Turris Sheila A SA 1Department of Emergency Medicine,University of British Columbia,Vancouver,British - - 2014
Current knowledge about mass-gathering health (MGH) fails to adequately inform the understanding of mass gatherings (MGs) because of a relative lack of theory development and adequate conceptual analysis. This report describes the development of a series of event lenses that serve as a beginning "MG event model," complimenting the "MG ...
Suinesiaputra Avan - - 2014
The burden of heart disease is rapidly worsening due to increasing prevalence of obesity and diabetes. Data sharing and open database resources for heart health informatics are important for advancing our understanding of cardiovascular function, disease progression and therapeutics. Data sharing enables valuable information, often obtained at considerable expense and ...
Boyd Matt M Centre for Medical and Health Sciences Education, The University of Auckland, Auckland, New - - 2014
Root cause analysis (RCA) is widely used to investigate adverse events in health care and is mandated by many organizations and governments. RCA employs a combination of techniques to establish the factors contributing to a harmful outcome. Once the factors are identified, then interventions are usually designed in order to ...
Couceiro R R Center for Informatics and Systems of the University of Coimbra, Polo II, 3030-290 Coimbra, - - 2014
The presence of motion artifacts in photoplethysmographic (PPG) signals is one of the major obstacles in the extraction of reliable cardiovascular parameters in continuous monitoring applications. In the current paper we present an algorithm for motion artifact detection based on the analysis of the variations in the time and the ...
Assink Mark M University of Amsterdam, The Netherlands - - 2014
For prevention purposes, it is important that police officers can estimate the risk for delinquency among juveniles who were involved in a criminal offense, but not in the role of a suspect. In the present study, the Youth Actuarial Risk Assessment Tool for First-Time Offending (Y-ARAT-FO) was developed based solely ...
Rantanen Johanna J Department of Teacher Education, University of Jyvaskyla, - - 2014
The present study investigated the factor structure of the 10-item version of the Dutch Work Addiction Scale (DUWAS). The DUWAS-10 is intended to measure workaholism with two correlated factors: working excessively (WE) and working compulsively (WC). The factor structure of the DUWAS-10 was examined among multi-occupational samples from the Netherlands ...
Demissei Biniyam G BG Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The - - 2014
Competing non-cardiovascular related deaths were not accounted for in the Systematic COronary Risk Evaluation (SCORE) model. In this study we assessed the impact of non-cardiovascular related deaths on the prognostic performance and yield of the SCORE model. 5,752 participants from the Prevention of Renal and Vascular End stage Disease cohort ...
Kahoul Riad R Novadiscovery SAS, 60 Avenue Rockefeller, 69008 Lyon, France UMR 5558, Laboratoire de Biométrie et Biologie Evolutive, CNRS, UCB Lyon 1 - Bât. Grégor Mendel, 43 bd du 11 novembre 1918, 69622 Villeurbanne cedex, France - - 2014
Healthcare authorities make difficult decisions about how to spend limited budgets for interventions that guarantee the best cost-efficacy ratio. We propose a novel approach for treatment decision-making, OMES-in French: Objectif thérapeutique Modèle Effet Seuil (in English: Therapeutic Objective-Threshold-Effect Model; TOTEM). This approach takes into consideration results from clinical trials, adjusted ...
Keskin Gündoğdu Tuğba T Department of Bioengineering, Ege University , Bornova-Izmir , - - 2014
Abstract Experimental design is a form of process analysis in which certain factors are selected to obtain the desired responses of interest. It may also be used for the determination of the effects of various independent factors on a dependent factor. The bioengineering discipline includes many different areas of scientific ...
Lloyd Jennifer T JT Research and Rapid-Cycle Evaluation Group, Center for Medicare & Medicaid Innovation, Centers for Medicare & Medicaid Services, Baltimore, MD, USA - - 2014
Population-level data on obesity are difficult to obtain. Claims-based data sets are useful for studying public health at a population level but lack physical measurements. The objective of this study was to determine the validity of a claims-based measure of obesity compared to obesity diagnosed with clinical data as well ...
Huberts W W Department of Biomedical Engineering, Eindhoven University of Technology, The Netherlands; Faculty of Health, Medicine and Life Sciences, Biomedical Engineering, Maastricht University, The - - 2014
Patient-specific modeling requires model personalization, which can be achieved in an efficient manner by parameter fixing and parameter prioritization. An efficient variance-based method is the generalized polynomial chaos expansion (gPCE), but it has not been applied in the context of model personalization, nor has it ever been compared to standard ...
Bolli Roberto R University of Louisville - - 2014
On the surface, it seems obvious - and, indeed, it is commonly assumed - that the best predictors of the scientific impact of a project are the novelty, methodology, feasibility, and importance of the proposed studies (as assessed by peer review groups). Accordingly, funding decisions by the NIH, AHA, and ...
Gallagher Cathal T CT Department of Pharmacy, University of Hertfordshire, Hatfield, Herts, - - 2014
The principal aims of this research were: to assess whether aggravating and mitigating circumstances considered by the General Pharmaceutical Council (GPhC) when imposing sanctions are considered when determining impairment of fitness to practise and to determine whether those circumstances described by the GPhC in their Indicative Sanctions Guidance (ISG) as ...
Ford Caroline S CS School of Agriculture, Food and Wine, University of Adelaide, Waite Campus, PMB 1, Glen Osmond, SA, 5064, - - 2014
Paternal biocontainment methods (PBMs) act by preventing pollen-mediated transgene flow. They are compromised by transgene escape via the crop-maternal line. We therefore assess the efficacy of PBMs for transgenic rapeseed (Brassica napus) biocontainment across the United Kingdom by estimating crop-maternal hybridization with its two progenitor species. We used remote sensing, ...
Waller Rebecca R University of Michigan, Ann Arbor, MI, - - 2014
The presence of callous-unemotional (CU) traits delineates a subgroup of youth with severe antisocial behavior. However, debate surrounds the best method to assess CU traits. This study examined the factor structure of the parent-reported Inventory of Callous-Unemotional Traits (ICU) among high-risk 9-year-olds (N = 540) and its predictive validity over ...
Deng Nina N Quantitative Health Sciences Department, University of Massachusetts Medical School, Worcester, MA, 01655, USA, - - 2014
Vitality is an important domain reflecting both the physical and emotional components of health-related quality of life. Because of its complexity, it has been defined and measured both broadly and narrowly. We explored the dimensionality of a very comprehensive item bank hypothesized to measure vitality and its related concepts. Secondary ...
Loehlin John C JC University of Texas at Austin, Austin, TX, - - 2014
Rotations of 1 to 12 factors were compared by Goldberg's "bass-ackward" method, with or without initially holding constant one or more principal components. Two sets of data were employed: ratings by 320 undergraduates using 435 personality-descriptive adjectives, and 512 Oregon community members' responses to 184 scales from 8 personality inventories. ...
Isidro Julio J Cornell University, Ithaca, NY, USA, - - 2014
Population structure must be evaluated before optimization of the training set population. Maximizing the phenotypic variance captured by the training set is important for optimal performance. The optimization of the training set (TRS) in genomic selection has received much interest in both animal and plant breeding, because it is critical ...
Carolan Kevin K Unité mixte de recherche (UMR) Maladies Infectieuses et Vecteurs: Écologie, Génétique, Evolution, et Contrôle (MIVEGEC) IRD-CNRS-Universities of Montpellier I and II, Centre IRD de Montpellier, Montpellier, France; UMR Territoires, Environnement, Télédétection et Information Spatiale (TETIS) CIRAD, Montpellier, France; Unité d'Epidémiologie de Maladies Emergentes, Institut Pasteur, Paris, - - 2014
An understanding of the factors driving the distribution of pathogens is useful in preventing disease. Often we achieve this understanding at a local microhabitat scale; however the larger scale processes are often neglected. This can result in misleading inferences about the distribution of the pathogen, inhibiting our ability to manage ...
Chung Dongjun D Department of Biostatistics, Yale School of Public Health, New Haven, Connecticut, United States of America; Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina, United States of - - 2014
Results from Genome-Wide Association Studies (GWAS) have shown that complex diseases are often affected by many genetic variants with small or moderate effects. Identifications of these risk variants remain a very challenging problem. There is a need to develop more powerful statistical methods to leverage available information to improve upon ...
Pavlovic Jelena M JM Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA; Montefiore Headache Center, Bronx, NY, - - 2014
In this second of a 2-part series, we review the available literature on trigger factors and premonitory features in migraine. In the absence of biological markers of preceding attacks of migraine, trigger factors and premonitory symptoms are valuable though methodologically challenging phenomena to study. We focus on selected studies of ...
Alem Mauro M Banco de Inversiones y Comercio Exterior - - 2014
The theory of the optimal allocation of risk and the Townsend Thai panel data on financial transactions are used to assess the impact of the major formal and informal financial institutions of an emerging market economy. We link financial institution assessment to the actual impact on clients, rather than ratios ...
García-Díaz Pablo P School of Earth & Environmental Sciences and the Environment Institute, The University of Adelaide, North Terrace, SA, 5005, - - 2014
Biological invasions are a key component of human-induced global change. The continuing increase in global wildlife trade has raised concerns about the parallel increase in the number of new invasive species. However, the factors that link the wildlife trade to the biological invasion process are still poorly understood. Moreover, there ...
Baker David M - - 2014
Examining whether disease cases are clustered in space is an important part of epidemiological research. Another important part of spatial epidemiology is testing whether patients suffering from a disease are more, or less, exposed to environmental factors of interest than adequately defined controls. Both approaches involve determining the number of ...
Allen Timothy Eric Harry - - 2014
Consumer and environmental safety decisions are based on exposure and hazard data, interpreted using risk assessment approaches. The adverse outcome pathway (AOP) conceptual framework has been presented as a logical sequence of events or processes within biological systems which can be used to understand adverse effects and refine current risk ...
Campagna Jesse J Texas Department of State Health Services, PO Box 149347, Austin, TX, 78756, - - 2014
This analysis presents a method for estimating the population of men who have sex with men (MSM) at the county and metropolitan area level in Texas. Surveillance data consistently demonstrate that MSM experience a high burden of HIV and other sexually transmitted infections (STIs). Numerous studies have shown that MSM ...
Park Gyung-Min GM From the Department of Cardiology, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Daejeon, Korea (G.-M.P., S.H.H.); Departments of Biostatistics (S.H., J.B.L., M.S.L.), Preventive Medicine (M.-W.J.), Cardiology, (J.-M.A., S.-W.L., Y.-H.K., S.-W.P., S,-J.P.), Endocrinology and Metabolism (B.-J.K., J.-M.K.), and Health Screening and Promotion Center (H.-K.K., J.C.), Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea; Department of Nursing, College of Medicine, Dankook University, Cheonan, Korea (S.H.K.); Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea (H.C.K.); and Research and Development Center, Health Insurance Review and Assessment Service, Seoul, Korea - - 2014
A model for predicting cardiovascular disease in Asian populations is limited. In total, 57 393 consecutive asymptomatic Korean individuals aged 30 to 80 years without a prior history of cardiovascular disease who underwent a general health examination were enrolled. Subjects were randomly classified into the train (n=45 914) and validation ...
Gabriel Erin E EE Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, - - 2014
Principal surrogate endpoints are useful as targets for phase I and II trials. In many recent trials, multiple post-randomization biomarkers are measured. However, few statistical methods exist for comparison of or combination of biomarkers as principal surrogates, and none of these methods to our knowledge utilize time-to-event clinical endpoint information. ...
Chang Xiaohui X College of Business, Oregon State University, Corvallis, Oregon, - - 2014
We propose a novel statistical framework by supplementing case-control data with summary statistics on the population at risk for a subset of risk factors. Our approach is to first form two unbiased estimating equations, one based on the case-control data and the other on both the case data and the ...
Gwak Kwan-Woong KW Department of Mechanical Engineering, Sejong University, Seoul, - - 2014
Physiological feasibility is the most important requirement for cardiovascular circulatory simulators (CCSs). However, previous simulators have been validated by a comparison with specific human data sets, which are valid only for very limited conditions, and so it is difficult to validate the fidelity of a CCS for various body conditions. ...
Bradshaw Corey J A CJ The Environment Institute and School of Earth and Environmental Sciences, The University of Adelaide, Adelaide, SA 5005, Australia - - 2014
The inexorable demographic momentum of the global human population is rapidly eroding Earth's life-support system. There are consequently more frequent calls to address environmental problems by advocating further reductions in human fertility. To examine how quickly this could lead to a smaller human population, we used scenario-based matrix modeling to ...
Furukawa Kyoji K Radiation Effects Research Foundation, Hiroshima, Japan - - 2014
While data are unavoidably missing or incomplete in most observational studies, consequences of mishandling such incompleteness in analysis are often overlooked. When time-varying information is collected irregularly and infrequently over a long period, even precisely obtained data may implicitly involve substantial incompleteness. Motivated by an analysis to quantitatively evaluate the ...
Carriker Neil E NE Tennessee Valley Authority, 6401 Harbor Master Drive, Hixson, TN, 37343. - - 2014
The Tennessee Valley Authority conducted a Baseline Ecological Risk Assessment (BERA) for the Kingston Fossil Plant ash release site to evaluate potential effects of residual coal ash on biota in Watts Bar Reservoir, Tennessee. The BERA was in response to a release of 4.1 million m(3) of coal ash on ...
Wu Yufeng Y Department of Computer Science and Engineering, University of Connecticut, Storrs, CT 06269, U.S.A. - - 2014
Population trees represent past population divergence histories. The inference of population trees can be useful for the study of population evolution. With the size of data increases in large-scale population genetic projects, such as the 1000 Genomes Project, there are new computational challenges for ancestral population inference, including population tree ...
Holland R C RC The Institute of Fundamental Sciences, Massey University,Palmerston North,New - - 2014
SUMMARY The search for an association between disease incidence and possible risk factors using surveillance data needs to account for possible spatial and temporal correlations in underlying risk. This can be especially difficult if there are missing values for some important covariates. We present a case study to show how ...
Dickson E D ED United States Nuclear Regulatory Commission, Rockville, - - 2014
This paper presents validated building shielding factors designed for contemporary US housing-stock under an idealized, yet realistic, exposure scenario within a semi-infinite cloud of radioactive material. The building shielding factors are intended for use in emergency planning and level three probabilistic risk assessments for a variety of postulated radiological events ...
Calabrese Edward J EJ a  Department of Public Health, Environmental Health Sciences, University of Massachusetts, Amherst, Massachusetts 01003; - - 2014
This article explores the origin of the linear no-threshold (LNT) dose-response model and how it came to be used in cancer risk assessment worldwide. Following this historical appraisal is an evaluation of the LNT model, within the framework of the BEIR VII report of the National Academy of Sciences, on ...
Dalgleish Tracy L TL Greenbelt Family Health Team, Ottawa Couple and Family - - 2014
In emotionally focused couple therapy (EFT), the blamer-softening event helps individuals express and respond to partners' unmet attachment needs. This study examined the impact of this event in relation to attachment at intake and changes in marital satisfaction from pre- to posttherapy. Thirty-two couples were provided an average of 21 ...
Oneto Luca - - 2014
The purpose of this paper is to obtain a fully empirical stability-based bound on the generalization ability of a learning procedure, thus, circumventing some limitations of the structural risk minimization framework. We show that assuming a desirable property of a learning algorithm is sufficient to make data-dependency explicit for stability, ...
1 2 3 4 5 6 7 8 9 10 >