Search Results
Results 1 - 50 of 1719
1 2 3 4 5 6 7 8 9 10 >
Jensen Mark P MP a University of Washington , Seattle , - - 2015
Abstract Evidence supports the efficacy of hypnotic treatments, but there remain many unresolved questions regarding how hypnosis produces its beneficial effects. Most theoretical models focus more or less on biological, psychological, and social factors. This scoping review summarizes the empirical findings regarding the associations between specific factors in each of ...
Banou Eirini E Department of Informatics, Ionian University, 7 Tsirigoti Square, Corfu, Greece, - - 2015
The present work aims to study extensively the literature on the phenomenon of "kinesia paradoxa" presented in Parkinson's disease patients, who generally cannot move but under certain circumstances exhibit a sudden, brief period of mobility (walking or even running). The objective of this study was to identify the mechanisms causing ...
Parsa Soroush S Centro Internacional de Agricultura Tropical (CIAT), Apartado Aéreo 6713, Cali, Colombia, - - 2014
The cassava green mites Mononychellus tanajoa and M. mcgregori are highly invasive species that rank among the most serious pests of cassava globally. To guide the development of appropriate risk mitigation measures preventing their introduction and spread, this article estimates their potential geographic distribution using the maximum entropy approach to ...
Louis Valérie R - - 2014
The global spread and the increased frequency and magnitude of epidemic dengue in the last 50 years underscore the urgent need for effective tools for surveillance, prevention, and control. This review aims at providing a systematic overview of what predictors are critical and which spatial and spatio-temporal modeling approaches are ...
Zadakbar Omid O Process Engineering, Faculty of Engineering and Applied Science, Memorial University of Newfoundland, St. John's, Newfoundland, Canada, A1B - - 2014
A comprehensive methodology for economic consequence analysis with appropriate models for risk analysis of process systems is proposed. This methodology uses loss functions to relate process deviations in a given scenario to economic losses. It consists of four steps: definition of a scenario, identification of losses, quantification of losses, and ...
Fleming Thomas R TR Department of Biostatistics, University of Washington, Seattle, WA, USA - - 2014
There is compelling evidence supporting the importance of maintaining confidentiality of interim data in clinical trials designed to reliably address the benefit-to-risk profile of interventions. While this is widely recognized, creative approaches are needed to achieve this in challenging settings where interim data are released for regulatory review and action, ...
Sohn Ji Seun JS Georgia College & State University, Milledgeville, USA - - 2014
There is no published work on different factor structures of the Psychopathy Checklist-Revised (PCL-R) for Korean offenders. The current study compared the two-, three-, and four-factor structures of the Korean version of the PCL-R. A total of 451 adult male serious offenders were included. The results suggested that both three- ...
Garcia-Reyero Natalia - - 2014
Social pressure to minimize the use of animal testing and the ever-increasing concern on animal welfare, together with the need for more human relevant and more predictive toxicity tests, are some of the drivers for new approaches to chemical screening. These approaches must also be able to accelerate the screening ...
Mwanga Gasper G GG Department of Mathematics and Physics, Lappeenranta University of Technology, P.O.Box 20, FI-53851 Lappeenranta, Finland. Electronic address: - - 2014
The main scope of this paper is to study the optimal control practices of malaria, by discussing the implementation of a catalogue of optimal control strategies in presence of parameter uncertainties, which is typical of infectious diseases data. In this study we focus on a deterministic mathematical model for the ...
Marostica Eleonora E University of Pavia, Via Ferrata 1, 27100, Pavia, Italy. Electronic address: - - 2014
This paper addresses the problem of modelling longitudinal data describing patients' responses in clinical trials. In particular, a systematic approach relying on a system theoretic paradigm is proposed to deal with contexts where limited physiopathological knowledge is available on disease, drug response, and patients' characteristics. The model relies on the ...
Keyhani Salomeh - - 2014
The Centers for Medicare & Medicaid Services (CMS) and Veterans Health Administration (VA) will report 30-day stroke readmission rates as a measure of hospital quality. A national debate on whether social risk factors should be included in models developed for hospital profiling is ongoing. To compare a CMS-based model of ...
Chappell Thomas M TM North Carolina State University, Department of Entomology, Raleigh, - - 2014
The codling moth, Cydia pomonella (L.) (Lepidoptera: Tortricidae), is major world-wide pest of apples, pears and walnuts. A temperature-driven phenological model of codling moth developed in Michigan has been utilized in North Carolina (NC) and other states for decades. Systematic inaccuracy of this model in predicting moth emergence in NC ...
Sayeed Taufique T Technical Research Centre for Dependency Care and Autonomous Living, Rambla de l'Exposicio, Vilanova i la Geltru, - - 2014
Parkinson's disease (PD) is a neurodegenerative disease that predominantly alters patients' motor performance. Reduced step length and inability of step are important symptoms associated with PD. Assessing patients' motor state monitoring step length helps to detect periods in which patients suffer lack of medication effect. Evaluate the adaption of existing ...
Fu Haoda H a Eli Lilly and Company , Indianapolis , IN , - - 2014
Abstract Diabetes affects an estimated 25.8 million people in the United States and is one of the leading causes of death. A major safety concern in treating diabetes is the occurrence of hypoglycemic events. Despite this concern, the current methods of analyzing hypoglycemic events, including the Wilcoxon rank sum test ...
Beamer Paloma I PI a Environmental Health Sciences, Mel and Enid Zuckerman College of Public Health , University of Arizona , 1295 N. Martin Ave., Tucson , Arizona 85724 , - - 2014
ABSTRACT Although the number of illnesses resulting from indirect viral pathogen transmission could be substantial, it is difficult to estimate the relative risks because of the wide variation and uncertainty in human behavior, variable viral concentrations on fomites, and other exposure factors. The purpose of this study was to evaluate ...
Braun Jean-Pierre JP Sciences cliniques, Université de Toulouse, UPS, INP, ENVT, UMS 0006, Toulouse, - - 2014
This article presents the general causes of preanalytic variability with a few examples showing specialists and practitioners that special and improved care should be given to this too often neglected phase. The preanalytic phase of clinical pathology includes all the steps from specimen collection to analysis. It is the phase ...
von Thiele Schwarz Ulrica U From the Medical Management Centre (Drs von Thiele Schwarz, Hasson, and Tafvelin), Department of Learning, Informatics, Management and Ethics, Karolinska Institutet; Department of Psychology (Drs von Thiele Schwarz and Sjöberg), Stockholm University; Centre for Epidemiology and Community Medicine (Dr Hasson), Stockholm County Council; and Department of Psychology (Dr Tafvelin), Umeå University, - - 2014
To test the factor structure and variance components of the productivity subscales of the Health and Work Questionnaire (HWQ). A total of 272 individuals from one company answered the HWQ scale, including three dimensions (efficiency, quality, and quantity) that the respondent rated from three perspectives: their own, their supervisor's, and ...
Slavin M A MA Department of Infectious Diseases and Infection Control, Peter MacCallum Cancer Centre, East Melbourne, Victoria; Victorian Infectious Diseases Service, The Doherty Institute for Infection and Immunity, Parkville, Victoria; School of Medicine, The University of Melbourne, Melbourne, - - 2014
This article introduces the second revision of the Australian and New Zealand consensus guidelines for the use of antifungal agents in the haematology/oncology setting. The current update occurs within the context of a growing population at risk of invasive fungal disease, improved understanding of risk factors, availability of new diagnostic tests, a ...
Mbuthia Jackson Mwenda JM Animal Breeding and Genomics Group, Department of Animal Sciences, Egerton University, P.O. Box 536-20115, Egerton, - - 2014
This study estimated economic values for production traits (dressing percentage (DP), %; live weight for growers (LWg), kg; live weight for sows (LWs), kg) and functional traits (feed intake for growers (FEEDg), feed intake for sow (FEEDs), preweaning survival rate (PrSR), %; postweaning survival (PoSR), %; sow survival rate (SoSR), ...
Nikolic Katarina K Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Institute of Pharmaceutical Chemistry, University of Belgrade, Vojvode Stepe 450, 11000, Belgrade, Serbia, - - 2014
Recently developed multi-targeted ligands are novel drug candidates able to interact with monoamine oxidase A and B; acetylcholinesterase and butyrylcholinesterase; or with histamine N-methyltransferase and histamine H3-receptor (H3R). These proteins are drug targets in the treatment of depression, Alzheimer's disease, obsessive disorders, and Parkinson's disease. A probabilistic method, the Parzen-Rosenblatt ...
Pizzol Lisa L Department of Environmental Sciences, Informatics and Statistics, Ca' Foscari University of Venice, - - 2014
Water management is one of the EU environmental priorities and it is one of the most serious challenges that today's major cities are facing. The main European regulation for the protection of water resources is represented by the Water Framework Directive (WFD) and the Groundwater Directive (2006/118/EC) which require the ...
Madden A M AM School of Life and Medical Sciences, University of Hertfordshire, Hatfield, - - 2014
Evaluation of body composition is an important part of assessing nutritional status and provides prognostically useful data and an opportunity to monitor the effects of nutrition-related disease progression and nutritional intervention. The aim of this narrative review is to critically evaluate body composition methodology in adults, focusing on anthropometric variables. ...
Hanna T P TP Division of Cancer Care and Epidemiology, Cancer Research Institute at Queen's University, Kingston, Ontario K7L3N6, Canada; Collaboration for Cancer Outcomes Research and Evaluation (CCORE), Ingham Institute, UNSW Australia, Liverpool, NSW, Australia. Electronic address: - - 2014
The measurement of population benefits is important for priority setting, economic evaluation and quality improvement. It also informs advocacy. In this article, the use of demand models to estimate the achievable benefit of cancer therapy is reviewed. Achievable benefit refers to the treatment benefit achievable under optimal conditions. The population ...
Forbes David D Australian Centre for Posttraumatic Mental Health and Department of Psychiatry, Level 3, 161 Barry St, Carlton 3053, Australia. Electronic address: - - 2014
Confirmatory factor analytic studies of the latent structure of DSM-5 PTSD symptoms using self-report data (Elhai et al., 2012; Miller et al., 2013) have found that the four-factor model implied by the DSM-5 diagnostic criteria provided adequate fit to their data. However, the fit of this model is yet to ...
Chow Sy-Miin SM The Pennsylvania State University, 413 Biobehavioral Health Building, University Park, PA, 16802 , USA, - - 2014
The past decade has evidenced the increased prevalence of irregularly spaced longitudinal data in social sciences. Clearly lacking, however, are modeling tools that allow researchers to fit dynamic models to irregularly spaced data, particularly data that show nonlinearity and heterogeneity in dynamical structures. We consider the issue of fitting multivariate ...
Vaz Frédéric M FM Laboratory Genetic Metabolic Disease (F0-224), Departments of Clinical Chemistry and Pediatrics, University of Amsterdam, Academic Medical Center (AMC), Amsterdam, 1105 AZ, The Netherlands, - - 2014
The technical advances in mass spectrometry, particularly the development of (ultra)-high-resolution/mass accuracy measurement capabilities in combination with refinement of soft ionization techniques, have increased the application and success of lipidomics to answer biological questions in relation to lipid metabolism. Together with other omics technologies, lipidomics has become an important tool ...
Baker Jannah - - 2014
Spatial analysis is increasingly important for identifying modifiable geographic risk factors for disease. However, spatial health data from surveys are often incomplete, ranging from missing data for only a few variables, to missing data for many variables. For spatial analyses of health outcomes, selection of an appropriate imputation method is ...
Bighamian Ramin - - 2014
In this study, we present a system identification approach to the mathematical modeling of hemodynamic responses to vasopressor-inotrope agents. We developed a hybrid model called the latency-dose-response-cardiovascular (LDC) model that incorporated (i) a low-order lumped latency model to reproduce the delay associated with the transport of vasopressor-inotrope agent and the ...
van Diepen Sean - - 2014
IntroductionIn medical and surgical intensive care units, clinical risk prediction models for readmission have been developed; however studies reporting the risks for cardiovascular intensive care unit (CVICU) readmission have been methodologically limited by small numbers of outcomes, unreported measures of calibration or discrimination, or a lack of information spanning the ...
Chen Xiang X Key Laboratory of Biomedical Information Engineering of Ministry of Education, Institute of Biomedical Engineering, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of - - 2014
Transient changes in cardiovascular regulatory activities are valuable for clinical monitoring and pathophysiological research. However, there is a lack of effective methods to evaluate short-term cardiovascular regulation. This study explores a photoplethysmography (PPG)-based multi-parameter analytical approach using the period, amplitude and baseline of PPG signals to quantitatively assess cardiovascular regulation ...
Zhang Zhiwei Z U.S. Food and Drug Administration, Silver Spring, USA - - 2014
A common problem in randomized clinical trials is nonignorable missingness, namely that the clinical outcome(s) of interest can be missing in a way that is not fully explained by the observed quantities. This happens when the continued participation of patients depends on the current outcome after adjusting for the observed ...
White Easton R - - 2014
Long-lived marine megavertebrates (e.g. sharks, turtles, mammals, and seabirds) are inherently vulnerable to anthropogenic mortality. Although some mathematical models have been applied successfully to manage these animals, more detailed treatments are often needed to assess potential drivers of population dynamics. In particular, factors such as age-structure, density-dependent feedbacks on reproduction, ...
Martin Adam - - 2014
BackgroundExisting reviews identify numerous studies of the relationship between urban built environment characteristics and obesity. These reviews do not generally distinguish between cross-sectional observational studies using single equation analytical techniques and other studies that may support more robust causal inferences. More advanced analytical techniques, including the use of instrumental variables ...
Turris Sheila A SA 1Department of Emergency Medicine,University of British Columbia,Vancouver,British - - 2014
Current knowledge about mass-gathering health (MGH) fails to adequately inform the understanding of mass gatherings (MGs) because of a relative lack of theory development and adequate conceptual analysis. This report describes the development of a series of event lenses that serve as a beginning "MG event model," complimenting the "MG ...
Kwon Oh Hoon OH Department of Civil and Environmental Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 305-701, South Korea. Electronic address: - - 2014
Transportation continues to be an integral part of modern life, and the importance of road traffic safety cannot be overstated. Consequently, recent road traffic safety studies have focused on analysis of risk factors that impact fatality and injury level (severity) of traffic accidents. While some of the risk factors, such ...
Suinesiaputra Avan - - 2014
The burden of heart disease is rapidly worsening due to increasing prevalence of obesity and diabetes. Data sharing and open database resources for heart health informatics are important for advancing our understanding of cardiovascular function, disease progression and therapeutics. Data sharing enables valuable information, often obtained at considerable expense and ...
Boyd Matt M Centre for Medical and Health Sciences Education, The University of Auckland, Auckland, New - - 2014
Root cause analysis (RCA) is widely used to investigate adverse events in health care and is mandated by many organizations and governments. RCA employs a combination of techniques to establish the factors contributing to a harmful outcome. Once the factors are identified, then interventions are usually designed in order to ...
Webb Brandon J BJ Division of Infectious Diseases, University of Utah, Salt Lake City, UT, USA; Division of Clinical Epidemiology and Infectious Diseases, Intermountain Medical Center, Salt Lake City, UT, USA. Electronic address: - - 2014
Clinical management of community-acquired pneumonia (CAP) is increasingly complicated by antibiotic resistance. CAP due to pathogens resistant to guideline-recommended drugs (CAP-DRP) has increased. 2005 ATS/IDSA guidelines introduced a new category, healthcare-associated pneumonia (HCAP), and recommend extended-spectrum antibiotic treatment for patients meeting HCAP criteria. However, the predictive value of the HCAP ...
Preti Antonio A Center of Liaison Psychiatry and Psychosomatics, University Hospital, University of Cagliari, Italy; Section on Clinical Psychology, Department of Education, Psychology, Philosophy, University of Cagliari, Italy; Genneruxi Medical Center, Cagliari, Italy. Electronic address: - - 2014
Sparse evidence of a co-aggregation of the risk of schizophrenia and bipolar disorder provides support for a shared but nonspecific genetic etiology of bipolar disorder and schizophrenia. Temperaments are conceptualized as trait sub-syndromic conditions of major pathologies. This study set out to test the hypothesis of a continuum between schizotypy ...
Couceiro R R Center for Informatics and Systems of the University of Coimbra, Polo II, 3030-290 Coimbra, - - 2014
The presence of motion artifacts in photoplethysmographic (PPG) signals is one of the major obstacles in the extraction of reliable cardiovascular parameters in continuous monitoring applications. In the current paper we present an algorithm for motion artifact detection based on the analysis of the variations in the time and the ...
Assink Mark M University of Amsterdam, The Netherlands - - 2014
For prevention purposes, it is important that police officers can estimate the risk for delinquency among juveniles who were involved in a criminal offense, but not in the role of a suspect. In the present study, the Youth Actuarial Risk Assessment Tool for First-Time Offending (Y-ARAT-FO) was developed based solely ...
Rantanen Johanna J Department of Teacher Education, University of Jyvaskyla, - - 2014
The present study investigated the factor structure of the 10-item version of the Dutch Work Addiction Scale (DUWAS). The DUWAS-10 is intended to measure workaholism with two correlated factors: working excessively (WE) and working compulsively (WC). The factor structure of the DUWAS-10 was examined among multi-occupational samples from the Netherlands ...
Demissei Biniyam G BG Department of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, The - - 2014
Competing non-cardiovascular related deaths were not accounted for in the Systematic COronary Risk Evaluation (SCORE) model. In this study we assessed the impact of non-cardiovascular related deaths on the prognostic performance and yield of the SCORE model. 5,752 participants from the Prevention of Renal and Vascular End stage Disease cohort ...
Kahoul Riad R Novadiscovery SAS, 60 Avenue Rockefeller, 69008 Lyon, France UMR 5558, Laboratoire de Biométrie et Biologie Evolutive, CNRS, UCB Lyon 1 - Bât. Grégor Mendel, 43 bd du 11 novembre 1918, 69622 Villeurbanne cedex, France - - 2014
Healthcare authorities make difficult decisions about how to spend limited budgets for interventions that guarantee the best cost-efficacy ratio. We propose a novel approach for treatment decision-making, OMES-in French: Objectif thérapeutique Modèle Effet Seuil (in English: Therapeutic Objective-Threshold-Effect Model; TOTEM). This approach takes into consideration results from clinical trials, adjusted ...
Keskin Gündoğdu Tuğba T Department of Bioengineering, Ege University , Bornova-Izmir , - - 2014
Abstract Experimental design is a form of process analysis in which certain factors are selected to obtain the desired responses of interest. It may also be used for the determination of the effects of various independent factors on a dependent factor. The bioengineering discipline includes many different areas of scientific ...
Lloyd Jennifer T JT Research and Rapid-Cycle Evaluation Group, Center for Medicare & Medicaid Innovation, Centers for Medicare & Medicaid Services, Baltimore, MD, USA - - 2014
Population-level data on obesity are difficult to obtain. Claims-based data sets are useful for studying public health at a population level but lack physical measurements. The objective of this study was to determine the validity of a claims-based measure of obesity compared to obesity diagnosed with clinical data as well ...
Huberts W W Department of Biomedical Engineering, Eindhoven University of Technology, The Netherlands; Faculty of Health, Medicine and Life Sciences, Biomedical Engineering, Maastricht University, The - - 2014
Patient-specific modeling requires model personalization, which can be achieved in an efficient manner by parameter fixing and parameter prioritization. An efficient variance-based method is the generalized polynomial chaos expansion (gPCE), but it has not been applied in the context of model personalization, nor has it ever been compared to standard ...
Bolli Roberto R University of Louisville - - 2014
On the surface, it seems obvious - and, indeed, it is commonly assumed - that the best predictors of the scientific impact of a project are the novelty, methodology, feasibility, and importance of the proposed studies (as assessed by peer review groups). Accordingly, funding decisions by the NIH, AHA, and ...
Gallagher Cathal T CT Department of Pharmacy, University of Hertfordshire, Hatfield, Herts, - - 2014
The principal aims of this research were: to assess whether aggravating and mitigating circumstances considered by the General Pharmaceutical Council (GPhC) when imposing sanctions are considered when determining impairment of fitness to practise and to determine whether those circumstances described by the GPhC in their Indicative Sanctions Guidance (ISG) as ...
Ford Caroline S CS School of Agriculture, Food and Wine, University of Adelaide, Waite Campus, PMB 1, Glen Osmond, SA, 5064, - - 2014
Paternal biocontainment methods (PBMs) act by preventing pollen-mediated transgene flow. They are compromised by transgene escape via the crop-maternal line. We therefore assess the efficacy of PBMs for transgenic rapeseed (Brassica napus) biocontainment across the United Kingdom by estimating crop-maternal hybridization with its two progenitor species. We used remote sensing, ...
1 2 3 4 5 6 7 8 9 10 >