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Zeković Ivana I Vinča Institute of Nuclear Sciences, University of Belgrade, P.O. Box 522, 11001 Belgrade, - - 2014
Novel optical spectroscopy and imaging methods may be valuable in the early detection of cancer. This paper reports differences in the luminescence responses of pigmented skin lesions (melanomas and nevi) and apparently normal non-pigmented human skin, based on analyses of synchronous luminescence spectroscopy measurements. Measurements were performed in the excitation ...
Graesbøll K K Department of Applied Mathematics and Computer Science, Technical University of Denmark, Lyngby, Denmark; National Veterinary Institute, Technical University of Denmark, Frederiksberg C, - - 2014
In 2007, bluetongue virus (BTV) was introduced to both Denmark (DK) and the United Kingdom (UK). For this reason, simulation models were built to predict scenarios for future incursions. The DK and UK models have a common description of within-herd dynamics, but differ greatly in their descriptions of between-herd spread, ...
Dahirel Maxime M CNRS - Université de Rennes 1, UMR 6553 Ecosystèmes, biodiversité, évolution (ECOBIO), 35042, Rennes, - - 2014
Intra- and inter-specific differences in movement behaviour play an important role in the ecology and evolution of animals, particularly in fragmented landscapes. As a consequence of rarer and generally more fragmented habitat, and because dispersal tends to disrupt benefits brought by local adaptation, theory predicts that mobility and dispersal should ...
Baczko I I University of Szeged, Pharmacology and Pharmacotherapy, Szeged, - - 2014
Despite the existence of some in vivo animal proarrhythmia models, the reliable prediction of the proarrhythmic risk associated with novel compounds under development remains unsatisfactory. Therefore, new models with better predictive value for proarrhythmic risk assessment are needed. In this study, we carried out the primary characterization of a new ...
Mayo Michael M Environmental Laboratory, US Army Engineer Research and Development Center, Vicksburg, MS, - - 2014
Life cycle assessment (LCA) is an evaluation method used by decision-makers to help assess the relative environmental impacts of various industrial processes. Despite that many LCA methods remain sensitive to uncertain input data, which can reduce the utility of their results, uncertainty arising from constituent LCA models remains poorly understood. ...
Lin Ray F RF a Department of Industrial Engineering and Management , Yuan Ze University , Chung-li , - - 2014
The corrective reaction time (tcr) is an essential motor property when modelling hand control movements. Many studies designed experiments to estimate tcr, but reported only group means with inconsistent definitions. This study proposes an alternative methodology using Drury's (1994) intermittent illumination model. A total of 24 participants performed circular tracking ...
Lac Andrew A Department of Psychology, Claremont Graduate University , Claremont, California , - - 2014
The article provides an introduction to interpreting meta-analysis in the context of synthesizing results of studies that examine the role of culture on drug use behaviors. Topics reviewed include using effect size to indicate the strength of a relationship in a primary study, combining effects in weighted models to yield ...
Harsch Melanie A MA Department of Biology, University of Washington, Seattle, Washington - - 2014
Abstract Life cycles can limit the abilities of species to track changing climatic conditions. We combined age or stage structure and a moving-habitat model to explore the effects of life history on the persistence of populations in the presence of climate change. We studied four dissimilar plant species in moving ...
Carcreff Ewen - - 2014
Ultrasonic inverse problems such as spike train deconvolution, synthetic aperture focusing, or tomography attempt to reconstruct spatial properties of an object (discontinuities, delaminations, flaws, etc.) from noisy and incomplete measurements. They require an accurate description of the data acquisition process. Dealing with frequency-dependent attenuation and dispersion is therefore crucial because ...
Loffredo Nicolas N Center for Research in Isotopes and Environmental Dynamics, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8572, Japan. Electronic address: - - 2014
The Fukushima accident dispersed significant amounts of radioactive cesium (Cs) in the landscape. Our research investigated, from June 2011 to November 2013, the mobility of leachable Cs in forests canopies. In particular, (137)Cs and (134)Cs activity concentrations were measured in rainfall, throughfall, and stemflow in broad-leaf and cedar forests in ...
Gu Li L Key Laboratory of Integrated Regulation and Resource Development on Shallow Lake of Ministry of Education, College of Environment, Hohai University, Nanjing 210098, China E-mail: zulinhua@hhu.edu.cn; National Engineering Research Center of Water Resources Efficient Utilization and Engineering Safety, Hohai University, Nanjing 210098, - - 2014
The dispersion characteristics of braided rivers are presently unclear. The comprehensive flow structure in a physical braided river model was measured and was used to estimate its dispersion coefficient tensor. The largest values of the longitudinal and transverse dispersion coefficients occurred in the separation zone in two anabranches. The separation ...
Carena Andrea - - 2014
The GN-model has been proposed as an approximate but sufficiently accurate tool for predicting uncompensated optical coherent transmission system performance, in realistic scenarios. For this specific use, the GN-model has enjoyed substantial validation, both simulative and experimental. Recently, however, it has been pointed out that its predictions, when used to ...
Nguyen Kiet A KA Air Force Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433, - - 2014
We present a generalized Kohn-Sham (KS) density functional theory (DFT) based effective fragment potential (EFP2-DFT) method for the treatment of solvent effects. Similar to the original Hartree-Fock (HF) based potential with fitted parameters for water (EFP1) and the generalized HF based potential (EFP2-HF), EFP2-DFT includes electrostatic, exchange-repulsion, polarization, and dispersion ...
Salama Guy G University of - - 2014
Sexual dimorphism is a well-established phenomenon, but its degree varies tremendously among species. Since the early days of Einthoven's development of the three-lead galvanometer ECG, we have known there are marked differences in QT intervals of men and women. It required over a century to appreciate the profound implications of ...
Eagles Debbie - - 2014
Previous studies investigating long-distance, wind-borne dispersal of Culicoides have utilised outbreaks of clinical disease (passive surveillance) to assess the relationship between incursion and dispersal event. In this study, species of exotic Culicoides and isolates of novel bluetongue viruses, collected as part of an active arbovirus surveillance program, were used for ...
Ferber Georg G Statistik Georg Ferber GmbH, Cagliostrostrasse 14, 4125 Riehen, - - 2014
Since ICH E14 was adopted by the US FDA and the EU CPMC in 2005, thorough QT studies have routinely been analysed by looking at the time-matched difference between (baseline corrected) QTcF or QTcI under the supra-therapeutic dose and placebo. A study is considered negative, if the two-sided 90% confidence ...
Cipelletti Luca L Laboratoire Charles Coulomb (L2C, UMR 5221 CNRS-Université Montpellier 2) , Place Eugène Bataillon, F-34095 Montpellier Cedex 5, - - 2014
Taylor dispersion analysis is an increasingly popular characterization method that measures the diffusion coefficient, and hence the hydrodynamic radius, of (bio)polymers, nanoparticles, or even small molecules. In this work, we describe an extension to current data analysis schemes that allows size polydispersity to be quantified for an arbitrary sample, thereby ...
Somerfield P J PJ Plymouth Marine Laboratory, Prospect Place, Plymouth PL1 3DH, UK. Electronic address: - - 2014
Sublittoral macrobenthic communities in the Skomer Marine Nature Reserve (SMNR), Pembrokeshire, Wales, were sampled at 10 stations in 1993, 1996, 1998, 2003, 2007 and 2009 using a Day grab and a 0.5 mm mesh. The time series is analysed using Similarities Profiles (SIMPROF) tests and associated methods. Q-mode analysis using clustering ...
Ranjard Louis L *Bioinformatics Institute, The University of Auckland, New - - 2014
Competition between organisms influences the processes governing the colonization of new habitats. As a consequence, species or populations arriving first at a suitable location may prevent secondary colonization. While adaptation to environmental variables (e.g., temperature, altitude, etc.) is essential, the presence or absence of certain species at a particular location ...
Rahman Ziyaur Z Division of Product Quality and Research, Center for Drug Evaluation and Research, Food and Drug Administration, - - 2014
The objective of the present research was to study the feasibility of using near-infrared (NIR) and Fourier transform infrared (FTIR)-based chemometric models in quantifying crystalline and amorphous tacrolimus from its sustained-release amorphous solid dispersion (ASD). ASD contained ethyl cellulose, hydroxypropyl methyl cellulose, and lactose monohydrate as carriers, and amorphous form ...
Sparve Erik E AstraZeneca R&D - - 2014
QTc interval prolongation in humans is usually predictable based on results from preclinical findings. This study confirms the signal from the preclinical cardiac repolarization models (hERG, Guinea pig MAP and dog telemetry) on the clinical effects on the QTc interval. A Thorough QT/QTc (TQT) study is generally required for bioavailable ...
Wardhana A H AH Parasitology Department, Indonesian Research Centre for Veterinary Science (Balai Besar Penelitian Veteriner), Bogor, Indonesia; Life Sciences Department, Natural History Museum, London SW7 5BD, - - 2014
The Old World screwworm (OWS) fly, Chrysomya bezziana, is an obligate parasite of livestock, and the myiasis caused by its larval infestations is economically important in Indonesia. The current spatial distribution of such a pest depends on two main factors: the current environmental conditions in which it can survive; and, ...
Chao Yi-Shan YS The Experimental Forest, National Taiwan University, Nantou, Taiwan Department of Biomedical Science and Environmental Biology, Kaohsiung Medical University, Kaohsiung, - - 2014
Pteris (Pteridaceae), comprising over 250 species, had been thought to be a monophyletic genus until the three monotypic genera Neurocallis, Ochropteris and Platyzoma were included. However, the relationships between the type species of the genus Pteris, P. longifolia, and other species are still unknown. Furthermore, several infrageneric morphological classifications have ...
Ben-Dayan Ido I Deutsches Elektronen-Synchrotron DESY, Theory Group, D-22603 Hamburg, - - 2014
Local measurements of the Hubble expansion rate are affected by structures like galaxy clusters or voids. Here we present a fully relativistic treatment of this effect, studying how clustering modifies the mean distance- (modulus-)redshift relation and its dispersion in a standard cold dark matter universe with a cosmological constant. The ...
Münkemüller Tamara T Laboratoire d'Ecologie Alpine, UMR CNRS 5553, University Joseph Fourier, Grenoble 1, BP 53, 38041 Grenoble Cedex 9, - - 2014
Phylogenetic diversity patterns are increasingly being used to better understand the role of ecological and evolutionary processes in community assembly. Here, we quantify how these patterns are influenced by scale choices in terms of spatial and environmental extent and organismic scales. European Alps. We applied 42 sampling strategies differing in ...
Dunn Ryan J K RJ RPS APASA Pty. Ltd., P.O. Box 1679, Surfers Paradise, Gold Coast City, Queensland, 4217, Australia, - - 2014
Numerical models are useful for predicting the transport and fate of contaminants in dynamic marine environments, and are increasingly a practical solution to environmental impact assessments. In this study, a three-dimensional hydrodynamic model and field data were used to validate a far-field dispersion model that, in turn, was used to ...
Norros Veera - - 2014
In species that disperse by airborne propagules an inverse relationship is often assumed between propagule size and dispersal distance. However, for microscopic spores the evidence for the relationship remains ambiguous. Lagrangian stochastic dispersion models that have been successful in predicting seed dispersal appear to predict similar dispersal for all spore ...
Rolph G D GD NOAA Air Resources Laboratory (ARL), NCWCP R/ARL, 5830 University Research Court, College Park, MD 20740, USA. Electronic address: - - 2014
The Hybrid Single Particle Lagrangian Integrated Trajectory (HYSPLIT) model, developed by the National Oceanic and Atmospheric Administration's Air Resources Laboratory, has been configured to simulate the dispersion and deposition of nuclear materials from a surface-based nuclear detonation using publicly available information on nuclear explosions. Much of the information was obtained ...
Mallinis Giorgos G Department of Forestry & Management of the Environment and Natural Resources, Democritus University of Thrace, Pantazidou 193, GR-68200 Orestiada, Greece. Electronic address: - - 2014
The aims of this study were to map and analyze land use/land cover transitions and landscape changes in the Parnitha and Penteli mountains, which surround the Athens metropolitan area of Attica, Greece over a period of 62years. In order to quantify the changes between land categories through time, we computed ...
Rodó Xavier X Institució Catalana de Recerca i Estudis Avançats, 08010 Barcelona, Catalonia, Spain;Unitat de Dinàmica i Impacte Climàtic (UDIC), Institut Català de Ciències del Clima, 08005 Barcelona, Catalonia, Spain; - - 2014
Evidence indicates that the densely cultivated region of northeastern China acts as a source for the wind-borne agent of Kawasaki disease (KD). KD is an acute, coronary artery vasculitis of young children, and still a medical mystery after more than 40 y. We used residence times from simulations with the ...
Meza Torres Esteban I EI Instituto de Botánica del Nordeste, CONICET-UNNE, Corrientes, Argentina, - - 2014
The objective of this exploratory work is to test the hypothesis that South American populations of Ophioglossum reticulatum L. derive from Africa. Spores cross the Atlantic transported by wind and arrive in South America in recurrent migration. Three-dimensional (backward and forward) trajectories of spores between Africa and South America were ...
Peters S O SO Department of Animal Science, Berry College, Mount Berry, GA, - - 2014
Assumptions of normality of residuals for carcass evaluation may make inferences vulnerable to the presence of outliers, but heavy-tail densities are viable alternatives to normal distributions and provide robustness against unusual or outlying observations when used to model the densities of residual effects. We compare estimates of genetic parameters by ...
Chen Ling-Yun LY Key Laboratory of Aquatic Botany and Watershed Ecology, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan 430074, Hubei, PR - - 2014
Haloragaceae are a cosmopolitan plant family with its centre of diversity in Australia. Here, we investigate the historical biogeography of the family and the role of vicariance or dispersal in shaping its current distribution. DNA sequences from ITS, matK and the trnK 5' and trnK 3' introns were obtained for ...
Postema Pieter G PG Heart Center, Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands. - - 2014
The evaluation of every electrocardiogram should also include an effort to interpret the QT interval to assess the risk of malignant arrhythmias and sudden death associated with an aberrant QT interval. The QT interval is measured from the beginning of the QRS complex to the end of the T-wave, and ...
Badrick Tony T Faculty of Health Science and Medicine, Bond University, - - 2014
Measurement uncertainty (MU) estimates can be used by clinicians in result interpretation for diagnosis and monitoring and by laboratories in assessing assay fitness for use and analytical troubleshooting. However, MU is not routinely used to assess the appropriateness of the analyte reporting interval. We describe the relationship between MU and ...
Rigatos Gerasimos G GG Unit of Industrial Automation, Industrial Systems Institute, Stadiou str, 26504, Rion Patras, Greece, - - 2014
The paper proposes a systematic method for fixed-point bifurcation analysis in circadian cells and similar biological models using interval polynomials theory. The stages for performing fixed-point bifurcation analysis in such biological systems comprise (i) the computation of fixed points as functions of the bifurcation parameter and (ii) the evaluation of ...
Malik Marek M St. Paul's Cardiac Electrophysiology, University of London, and Imperial College, London, - - 2014
The Holter bin method evaluates QT interval changes in the presence of heart rate changes without correcting the QT interval. However, the method does not allow time-matched comparisons, thus contradicting available guidance and good practice. We report a modification of the methods that allows time-matched comparisons without any heart rate ...
Wu Yage Y Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, - - 2014
We conducted a door-to-door survey in a residential census tract of Philadelphia to estimate the prevalence and spatial patterns of recent bed bug infestations. We interviewed 596 residents, of whom 66 (11.1%) reported recent bed bug infestations. We confirmed current infestations in a subset of 15 (68.2%) of 22 inspected ...
Yang-Yin Lin - - 2014
This paper describes a self-evolving interval type-2 fuzzy neural network (FNN) for various applications. As type-1 fuzzy systems cannot effectively handle uncertainties in information within the knowledge base, we propose a simple interval type-2 FNN, which uses interval type-2 fuzzy sets in the premise and the Takagi-Sugeno-Kang (TSK) type in ...
- - 2014
[This corrects the article DOI: 10.1371/journal.pbio.1001821.].
Villarreal Juan Carlos JC Systematic Botany and Mycology, University of Munich (LMU), Germany. Electronic address: - - 2014
Absolute times from calibrated DNA phylogenies can be used to infer lineage diversification, the origin of new ecological niches, or the role of long distance dispersal in shaping current distribution patterns. Molecular-clock dating of non-vascular plants, however, has lagged behind flowering plant and animal dating. Here, we review dating studies ...
Lagache Lélia L INRA, UMR 1202 Biogeco, F- 33610, Cestas, France; Univ. Bordeaux, UMR1202 Biogeco, F-33400, Talence, - - 2014
Reproductive strategies of closely related species distributed along successional gradients should differ as a consequence of the trade-off between competition and colonization abilities. We compared male reproductive strategies of Quercus robur and Q. petraea, two partly interfertile European oak species with different successional status. In the studied even-aged stand, trees of the ...
Morin Sébastien S PROTEO, Université Laval, Québec G1V 0A6, Canada, International AIDS Society HQ, CH-1202 Geneva, Switzerland, Department of Biology, University of Copenhagen, DK-2200 Denmark, Institut de Biologie Structurale, Grenoble F-38027, France, Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK, Institute of Organic Chemistry & CMBI, University of Innsbruck, A-6020, Austria and NMR-based Structural Biology, Max Planck Institute for Biophysical Chemistry, D-37077 Göttingen, - - 2014
Nuclear magnetic resonance (NMR) is a powerful tool for observing the motion of biomolecules at the atomic level. One technique, the analysis of relaxation dispersion phenomenon, is highly suited for studying the kinetics and thermodynamics of biological processes. Built on top of the relax computational environment for NMR dynamics is ...
Liu Xuan X Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, 1 Beichen West Road, Chaoyang District, Beijing, 100101, - - 2014
Understanding the factors that determine rates of range expansion is not only crucial for developing risk assessment schemes and management strategies for invasive species, but also provides important insight into the ability of species to disperse in response to climate change. However, there is little knowledge on why some invasions ...
Duthie A Bradley AB Department of Ecology, Evolution, and Organismal Biology, Iowa State University, Ames, Iowa - - 2014
Abstract Ecological communities in which organisms complete their life cycles on discrete ephemeral patches are common and often support an unusually large number of species. Explaining this diversity is challenging for communities of ecologically similar species undergoing preemptive competition, where classic coexistence mechanisms may not readily apply. We use nonpollinating ...
Manktelow Bradley N BN Department of Health Sciences, University of Leicester, Leicester, - - 2014
There is an increasing use of statistical methods, such as funnel plots, to identify poorly performing healthcare providers. Funnel plots comprise the construction of control limits around a benchmark and providers with outcomes falling outside the limits are investigated as potential outliers. The benchmark is usually estimated from observed data ...
Shaw Allison K AK Division of Evolution, Ecology and Genetics, Research School of Biology, The Australian National University, Canberra, ACT 0200, Australia; Department of Ecology, Evolution, and Behavior, University of Minnesota, St. Paul, MN, - - 2014
Although dispersal requires context-dependent decision-making in three distinct stages (emigration, transit, immigration), these decisions are commonly ignored in simple models of dispersal. For sexually reproducing organisms, mate availability is an important factor in dispersal decisions. Difficulty finding mates can lead to an Allee effect where population growth decreases at low ...
Leadbetter Susan J SJ Met Office, Exeter, United Kingdom. Electronic address: - - 2014
This paper describes an investigation into the impact of different meteorological data sets and different wet scavenging coefficients on the model predictions of radionuclide deposits following the accident at the Fukushima Dai-ichi nuclear power plant in March 2011. Three separate operational meteorological data sets, the UK Met Office global meteorology, ...
Saito Kazuo K JMA Meteorological Research Institute, 1-1, Nagamine, Tsukuba, Ibaraki 305-0052, Japan. Electronic address: - - 2014
The World Meteorological Organization (WMO) convened a small technical task team of experts to produce a set of meteorological analyses to drive atmospheric transport, dispersion and deposition models (ATDMs) for the United Nations Scientific Committee on the Effects of Atomic Radiation's assessment of the Fukushima Daiichi Nuclear Power Plant (DNPP) ...
Zhang Junqi - - 2014
An update scheme of the state probability vector of actions is critical for learning automata (LA). The most popular is the pursuit scheme that pursues the estimated optimal action and penalizes others. This paper proposes a reverse philosophy that leads to last-position elimination-based learning automata (LELA). The action graded last ...
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