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Yan Xiao-Yong XY School of Systems Science, Beijing Normal University, Beijing 100875, People's Republic of China Department of Transportation Engineering, Shijiazhuang Tiedao University, Shijiazhuang 050043, People's Republic of - - 2014
Despite the long history of modelling human mobility, we continue to lack a highly accurate approach with low data requirements for predicting mobility patterns in cities. Here, we present a population-weighted opportunities model without any adjustable parameters to capture the underlying driving force accounting for human mobility patterns at the ...
Stanton Jessica C JC Department of Ecology and Evolution, Stony Brook University, Stony Brook, NY, 11794, - - 2014
Climate change is likely to become an increasingly major obstacle to slowing the rate of species extinctions. Several new assessment approaches have been proposed for identifying climate-vulnerable species, based on the assumption that established systems such as the IUCN Red List need revising or replacing because they were not developed ...
Debanne T T Laboratory CIAMS, University Paris-Sud Orsay, Orsay, - - 2014
This study was based on the naturalistic decision-making paradigm and regulatory focus theory. Its aim was to model coaches' decision-making processes for handball teams' defensive systems based on relevant cues of the reward structure, and to determine the weight of each of these cues. We collected raw data by video-recording ...
Dellicour Simon S Evolutionary Biology and Ecology, Université Libre de Bruxelles, av. FD Roosevelt 50, 1050 Brussels, Belgium Present address: Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom - - 2014
Computer simulations of genetic data are increasingly used to investigate the impact of complex historical scenarios on patterns of genetic variation. Yet, in most empirical studies, relatively large portions of species ranges are often treated as panmictic populations, ignoring the underlying spatial context. In some cases, however, a more accurate ...
Bottesi Gioia G a Department of General Psychology , University of Padua , Padua , - - 2014
Questionnaires generate numerical scores, but endorsing different sets of items could produce the same score despite reflecting qualitatively different configurations of clinical features. Formal psychological assessment (FPA) attempts to overcome this by identifying the clinical features entailed by observed response patterns. This study illustrates an application of FPA to the ...
Kalantari Zahra Z Department of Land and Water Resources, Royal Institute of Technology/KTH, SE-10044 Stockholm, Sweden; Department of Physical Geography and Quaternary Geology, Stockholm University, SE-106 91 Stockholm, Sweden. Electronic address: - - 2014
Identifying a 'best' performing hydrologic model in a practical sense is difficult due to the potential influences of modeller subjectivity on, for example, calibration procedure and parameter selection. This is especially true for model applications at the event scale where the prevailing catchment conditions can have a strong impact on ...
Kim Seon-Ha - - 2014
BackgroundThere is no research on mapping algorithms between EQ-5D and SF-36 in Korea. The aim of this study was to derive a predictive model for converting the SF-36 health profile to the EQ-5D index using data from several studies.MethodsIndividual data (n¿=¿2211) were collected from three different studies and separated into ...
Quiroz Zaida C ZC Department of Statistics, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, - - 2014
The Northern Humboldt Current System (NHCS) is the world's most productive ecosystem in terms of fish. In particular, the Peruvian anchovy (Engraulis ringens) is the major prey of the main top predators, like seabirds, fish, humans, and other mammals. In this context, it is important to understand the dynamics of ...
Buzbas Erkan O EO Department of Biology, Stanford University, Stanford, CA 94305-5020, USA; Department of Statistical Science, University of Idaho, Moscow, ID 84844-1104, USA. Electronic address: - - 2014
Approximate Bayesian computation (ABC) methods perform inference on model-specific parameters of mechanistically motivated parametric models when evaluating likelihoods is difficult. Central to the success of ABC methods, which have been used frequently in biology, is computationally inexpensive simulation of data sets from the parametric model of interest. However, when simulating ...
Frone Michael R - - 2014
This study develops and tests a new conceptual model of perceived physical availability of alcohol at work that provides unique insight into 3 dimensions of workplace physical availability of alcohol and their direct and indirect relations to workplace alcohol use and impairment. Data were obtained from a national probability sample ...
Hasegawa Takanori T 1 Bioinformatics Center, Institute for Chemical Research, Kyoto University , Gokasho, Uji, Kyoto, Japan - - 2014
Abstract Gene regulatory networks (GRNs) play a central role in sustaining complex biological systems in cells. Although we can construct GRNs by integrating biological interactions that have been recorded in literature, they can include suspicious data and a lack of information. Therefore, there has been an urgent need for an ...
Litterman Nadia K - - 2014
In a decade with over half a billion dollars of investment, more than 300 chemical probes have been identified to have biological activity through NIH funded screening efforts. We have collected the evaluations of an experienced medicinal chemist on the likely chemistry quality of these probes based on a number ...
Nielsen Morten Birkeland MB National Institute of Occupational Health, PB 8149 Dep, 0033 Oslo, Norway. - - 2014
The aim of this two-wave prospective study was to determine how and when job demands are related to alcohol use among employees. By integrating the Job Demands-Control model with the Tension-Reduction theory, we tested a conditional process (moderated mediation) model in which job demands were suggested to have an indirect ...
Kearns Robin A RA The University of Auckland, New - - 2014
Island blue spaces are associated with restorative potential, but few studies examine this proposition when an island׳s use has changed over time. We examine Rotoroa Island (near Auckland, New Zealand) where, for almost a century, the Salvation Army ran an alcohol treatment facility. The island׳s relative isolation was central to ...
Siniscalco Consolata C Department of Life Sciences and Systems Biology, University of Torino, Viale Mattioli, 25, 10125, Torino, Italy, - - 2014
Aerobiological data can be used as indirect but reliable measures of flowering phenology to analyze the response of plant species to ongoing climate changes. The aims of this study are to evaluate the performance of several phenological models for predicting the pollen start of season (PSS) in seven spring-flowering trees ...
Cai Li L CRESST, University of California, Los Angeles, CA, 90095-1521, USA, - - 2014
Lord and Wingersky's (Appl Psychol Meas 8:453-461, 1984) recursive algorithm for creating summed score based likelihoods and posteriors has a proven track record in unidimensional item response theory (IRT) applications. Extending the recursive algorithm to handle multidimensionality is relatively simple, especially with fixed quadrature because the recursions can be defined ...
Schofield Lynne Steuerle LS Department of Mathematics and Statistics, Swarthmore College, 500 College Avenue, Swarthmore, PA, 19081, USA, - - 2014
Plausible values (PVs) are a standard multiple imputation tool for analysis of large education survey data, which measures latent proficiency variables. When latent proficiency is the dependent variable, we reconsider the standard institutionally generated PV methodology and find it applies with greater generality than shown previously. When latent proficiency is ...
Peters Howard H Environment Department, University of York, YO10 5DD, Heslington, York, - - 2014
The International Union for Conservation of Nature Red List of Endangered Species employs a robust, standardised approach to assess extinction threat focussed on taxa approaching an end-point in population decline. Used alone, we argue this enforces a reactive approach to conservation. Species not assessed as threatened but which occur predominantly ...
Jiang Lingling - - 2014
Pharmacophore modeling incorporates geometric and chemical features of known inhibitors and/or targeted binding sites to rationally identify and design new drug leads. In this study, we have encoded a three-dimensional pharmacophore matching similarity (FMS) scoring function into the structure-based design program DOCK. Validation and characterization of the method are presented ...
Burns Randal R Institute for Data-Intensive Science and Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA; Department of Computer Science, The Johns Hopkins University, Baltimore, MD 21218, USA. Electronic address: - - 2014
The analysis of data requires computation: originally by hand and more recently by computers. Different models of computing are designed and optimized for different kinds of data. In data-intensive science, the scale and complexity of data exceeds the comfort zone of local data stores on scientific workstations. Thus, cloud computing ...
Warnell I I Department of Anaesthesia, Royal Victoria Infirmary, Newcastle upon Tyne NHS Foundation Trust, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK - - 2014
Summary Predicting risk of perioperative mortality after oesophagectomy for cancer may assist patients to make treatment choices and allow balanced comparison of providers. The aim of this systematic review of multivariate prediction models is to report their performance in new patients, and compare study methods against current recommendations. We used ...
Roposch Andreas A Institute of Child Health, University College London, London, United Kingdom; Department of Orthopaedic Surgery, Great Ormond Street Hospital for Children, London, United Kingdom. Electronic address: - - 2014
To establish clinical diagnostic criteria for developmental dysplasia of the hip (DDH) that model the practices of expert clinicians. Of 23 clinical criteria for the diagnosis of DDH, ranked in order of diagnostic importance by international consensus, the 7 most highly ranked were placed in all possible combinations to create ...
Proskurnikov Anton - - 2014
This paper addresses consensus problems in nonlinearly coupled networks of dynamic agents described by a common and arbitrary linear model. Interagent interaction rules are uncertain but satisfy the standard sector condition with known sector bounds; both the agent's model and interaction topology are time-invariant. A novel frequency-domain criterion for consensus ...
Wang Kenneth T - - 2014
The Cross-Cultural Loss Scale (CCLS), a measure of loss associated with crossing national boundaries, was developed across 2 samples of international students. With Sample 1 (N = 262), exploratory factor analyses were used to select the 14 CCLS items and to determine 3 factors: Belonging-Competency (α = .87), National Privileges ...
Tseng Yi-Ju - - 2014
A description of patient conditions should consist of the changes in and combination of clinical measures. Traditional data-processing method and classification algorithms might cause clinical information to disappear and reduce prediction performance. To improve the accuracy of clinical-outcome prediction by using multiple measurements, a new multiple-time-series data-processing algorithm with period ...
Sun Huiyong H Institute of Functional Nano and Soft Materials (FUNSOM), Jiangsu Key Laboratory for Carbon-Based Functional Materials and Devices and Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu 215123, P. R. China. tingjunhou@zju.edu.cn - - 2014
With the rapid development of computational techniques and hardware, more rigorous and precise theoretical models have been used to predict the binding affinities of a large number of small molecules to biomolecules. By employing continuum solvation models, the MM/GBSA and MM/PBSA methodologies achieve a good balance between low computational cost ...
Rørbech Jakob Thaysen - - 2014
Resources have received significant attention in recent years resulting in development of a wide range of resource depletion indicators within Life Cycle Assessment (LCA). Understanding the differences in assessment principles used to derive these indicators and the effects on the impact assessment results is critical for indicator selection and interpretation ...
Dziak John J JJ The Methodology Center, Pennsylvania State University, University Park, PA, 16802, - - 2014
Ordinal responses are very common in longitudinal data collected from substance abuse research or other behavioral research. This study develops a new statistical model with free SAS macros that can be applied to characterize time-varying effects on ordinal responses. Our simulation study shows that the ordinal-scale time-varying effects model has ...
Chung Eun-Sung ES Seoul National University of Science and Technology, Seoul, Republic of - - 2014
This study proposed a robust prioritization framework to identify the priorities of treated wastewater (TWW) use locations with consideration of various uncertainties inherent in the climate change scenarios and the decision-making process. First, a fuzzy concept was applied because future forecast precipitation and their hydrological impact analysis results displayed significant ...
Watt Torquil - - 2014
Background and aimThyroid diseases are prevalent and chronic. With treatment, quality of life is restored in most, but not all patients. Construct validity of the thyroid-related quality of life questionnaire, ThyPRO, has been established by multi-trait scaling, but not evaluated with more elaborate methods. The purpose of the present study ...
Fan Ruzong R Biostatistics and Bioinformatics Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of - - 2014
By using functional data analysis techniques, we developed generalized functional linear models for testing association between a dichotomous trait and multiple genetic variants in a genetic region while adjusting for covariates. Both fixed and mixed effect models are developed and compared. Extensive simulations show that Rao's efficient score tests of ...
Whelan Simon S Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, SE Faculty of Life Sciences, University of Manchester, Manchester, UK - - 2014
Molecular phylogenetics is a powerful tool for inferring both the process and pattern of evolution from genomic sequence data. Statistical approaches, such as maximum likelihood and Bayesian inference, are now established as the preferred methods of inference. The choice of models that a researcher uses for inference is of critical ...
Awad Zaid Z Department of Surgery and Cancer , Imperial College, London; Department of Otolaryngology , St. Mary's Hospital, Imperial College Healthcare NHS Trust, London, United - - 2014
To demonstrate construct validity of the ovine model as a tool for training in endoscopic sinus surgery (ESS). Prospective, cross-sectional evaluation study. Over 18 consecutive months, trainees and experts were evaluated in their ability to perform a range of tasks (based on previous face validation and descriptive studies conducted by ...
Gonzàlez J J 1IRTA,Finca Camps i Armet,17121 - - 2014
A market conformity tool, based on technological meat quality parameters, was developed within the Q-PorkChains project, to be included in a global sustainability evaluation of pig farming systems. The specific objective of the market conformity tool was to define a scoring system based on the suitability of meat to elaborate ...
Xu Meng M Carnegie Institution for Science, Department of Plant Biology, 260 Panama Street, Stanford CA 94305, - - 2014
Plant biology is becoming a data-driven science. High-throughput technologies generate data quickly from molecular to ecosystem levels. Statistical and computational approaches enable describing and interpreting data quantitatively. We highlight the purpose, common problems, and general principles in data analysis. We use RNA sequencing (RNAseq) analysis to illustrate the rationale behind ...
Gawlik Stephanie S Department of Obstetrics and Gynaecology, University of Heidelberg, Im Neuenheimer Feld 440, 69120 Heidelberg, Germany. Electronic address: - - 2014
validated questionnaire assessment of fathers׳ experiences during childbirth is lacking in routine clinical practice. Salmon׳s Item List is a short, validated method used for the assessment of birth experience in mothers in both English- and German-speaking communities. With little to no validated data available for fathers, this pilot study aimed ...
Onukwugha Eberechukwu E Department of Pharmaceutical Health Services Research, University of Maryland School of Pharmacy, 220 Arch Street, 12th Floor, Baltimore, MD, 21201, USA, - - 2014
Marginal analysis evaluates changes in an objective function associated with a unit change in a relevant variable. The primary statistic of marginal analysis is the marginal effect (ME). The ME facilitates the examination of outcomes for defined patient profiles while measuring the change in original units (e.g., costs, probabilities). The ...
Chen Shyi-Ming - - 2014
In this paper, we propose a new weighted fuzzy interpolative reasoning method for sparse fuzzy rule-based systems based on the slopes of fuzzy sets. We also propose a particle swarm optimization (PSO)-based weights-learning algorithm to automatically learn the optimal weights of the antecedent variables of fuzzy rules for weighted fuzzy ...
Anderman Eric M EM The Ohio State University, Columbus, Ohio, - - 2014
There is much interest in assessing growth in student learning. Assessments of growth have important implications and affect many policy decisions at many levels. In the present article, we review some of the different approaches to measuring growth and examine the implications of their usage. Samples used in research on ...
Ramsingh Davinder D Department of Anesthesiology, University of California at Irvine Medical Center, Orange, CA 92868, USA. Electronic address: - - 2014
To expose residents to two methods of education for point-of-care ultrasound, a traditional didactic lecture and a model/simulation-based lecture, which focus on concepts of cardiopulmonary function, volume status, and evaluation of severe thoracic/abdominal injuries; and to assess which method is more effective. Single-center, prospective, blinded trial. University hospital. Anesthesiology residents ...
Lensink Marc F MF CNRS USR3078, University Lille North of France, Parc de la Haute Borne, 50 avenue de Halley, F-59658, Villeneuve d'Ascq, - - 2014
CAPRI (Critical Assessment of PRedicted Interactions) has proven to be a catalyst for the development of docking algorithms. An essential step in docking is the scoring of predicted binding modes in order to identify stable complexes. In 2005, CAPRI introduced the scoring experiment, where upon completion of a prediction round, ...
Price Mathew M Neurobehavioral Research, Inc., Ala Moana Pacific Center, 1585 Kapiolani Blvd. Suite 1030, Honolulu, HI - - 2014
Although the human cerebellum has been increasingly identified as an important hub that shows potential for helping in the diagnosis of a large spectrum of disorders, such as alcoholism, autism, and fetal alcohol spectrum disorder, the high costs associated with manual segmentation, and low availability of reliable automated cerebellar segmentation ...
Michel Mirco M Department of Biochemistry and Biophysics, Stockholm University, 10691 Stockholm, Sweden, Science for Life Laboratory, Stockholm University, Box 1031, 17121 Solna, Sweden, Department of Systems Biology, Harvard Medical School, Boston, MA, USA, Department of Information and Computer Science, Aalto University, PO Box 15400, FI-00076 Aalto, Finland and Computational Biology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA Department of Biochemistry and Biophysics, Stockholm University, 10691 Stockholm, Sweden, Science for Life Laboratory, Stockholm University, Box 1031, 17121 Solna, Sweden, Department of Systems Biology, Harvard Medical School, Boston, MA, USA, Department of Information and Computer Science, Aalto University, PO Box 15400, FI-00076 Aalto, Finland and Computational Biology, Memorial Sloan-Kettering Cancer Center, New York, NY, - - 2014
Recently it has been shown that the quality of protein contact prediction from evolutionary information can be improved significantly if direct and indirect information is separated. Given sufficiently large protein families, the contact predictions contain sufficient information to predict the structure of many protein families. However, since the first studies ...
Gobbi Andrea A Fondazione Bruno Kessler, I-38100 Povo (Trento), Italy, European Molecular Biology Laboratory, European Bioinformatics Institute, Cambridge CB10 1SD, UK, Wellcome Trust Sanger Institute, Cambridge CB10 1SD, UK and Universitat Pompeu Fabra, Barcelona 08003, - - 2014
Studying combinatorial patterns in cancer genomic datasets has recently emerged as a tool for identifying novel cancer driver networks. Approaches have been devised to quantify, for example, the tendency of a set of genes to be mutated in a 'mutually exclusive' manner. The significance of the proposed metrics is usually ...
Oates Chris J CJ Department of Statistics, University of Warwick, Coventry, CV4 7AL, MRC Biostatistics Unit, Cambridge, CB2 0SR, UK, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94710, Department of Biomedical Engineering, Knight Cancer Institute, Oregon Health and Science University, Portland, OR 97239-3098, USA and School of Clinical Medicine, University of Cambridge, Cambridge, CB2 0SP, - - 2014
Networks are widely used as structural summaries of biochemical systems. Statistical estimation of networks is usually based on linear or discrete models. However, the dynamics of biochemical systems are generally non-linear, suggesting that suitable non-linear formulations may offer gains with respect to causal network inference and aid in associated prediction ...
Lindgren O O Department of Behavioural Sciences and Philosophy, Unit of Philosophy, University of Turku, - - 2014
There are several different approaches in the treatment of alcohol dependence. These approaches can be generalized into two different treatment paradigms. Explanatory models are theories that answer to the question about the nature of alcohol dependence and what kind of condition it should be thought as. My aim is to ...
Khan Kamran A KA Warwick Clinical Trials Unit, Division of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK. Electronic address: - - 2014
The Roland Morris Questionnaire (RMQ) is a widely used health status measure for low back pain (LBP). It is not preference-based, and there are currently no established algorithms for mapping between the RMQ and preference-based health-related quality-of-life measures. Using data from randomized controlled trials of treatment for LBP, we sought ...
Stefan Melanie I MI Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, United States of - - 2014
Multi-state modeling of biomolecules refers to a series of techniques used to represent and compute the behavior of biological molecules or complexes that can adopt a large number of possible functional states. Biological signaling systems often rely on complexes of biological macromolecules that can undergo several functionally significant modifications that ...
Sulthana Ayesha A Department of Water and Health - JSS University, S.S. Nagar, Mysore-570 015, Karnataka, India E-mail: - - 2014
Fuzzy principal component regression (FPCR) is proposed to model the non-linear process of sewage treatment plant (STP) data matrix. The dimension reduction of voluminous data was done by principal component analysis (PCA). The PCA score values were partitioned by fuzzy-c-means (FCM) clustering, and a Takagi-Sugeno-Kang (TSK) fuzzy model was built ...
Guo Rui R School of Economics and Management, China University of Geosciences, Wuhan, China / Center for Digital Business and Intelligent Management, DBIM, China University of Geosciences, Wuhan, - - 2014
From corporate internal governance structure and external institutional environment, this study uses a legitimacy perspective of intuitional theory to analyze the main influence factors on corporate environmental protection inputs and propose some hypotheses. With the establishment of empirical models, it analyzes the data of 2004-2009 listed biological and other companies ...
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