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Achdou Yves Y Université Paris Diderot, Sorbonne Paris Cité, Laboratoire Jacques-Louis Lions, Paris, - - 2014
The purpose of this article is to get mathematicians interested in studying a number of partial differential equations (PDEs) that naturally arise in macroeconomics. These PDEs come from models designed to study some of the most important questions in economics. At the same time, they are highly interesting for mathematicians ...
Yan Xiao-Yong XY School of Systems Science, Beijing Normal University, Beijing 100875, People's Republic of China Department of Transportation Engineering, Shijiazhuang Tiedao University, Shijiazhuang 050043, People's Republic of - - 2014
Despite the long history of modelling human mobility, we continue to lack a highly accurate approach with low data requirements for predicting mobility patterns in cities. Here, we present a population-weighted opportunities model without any adjustable parameters to capture the underlying driving force accounting for human mobility patterns at the ...
Bassiou Nikoletta K - - 2014
A novel method is proposed for updating an already trained asymmetric and symmetric probabilistic latent semantic analysis (PLSA) model within the context of a varying document stream. The proposed method is coined online PLSA (oPLSA). The oPLSA employs a fixed-size moving window over a document stream to incorporate new documents ...
Arima Serena S Dipartimento di Metodi e Modelli per l'Economia, il Territorio e la Finanza, Sapienza Università di Roma, Rome, - - 2014
With reference to a questionnaire that aimed to assess the quality of life for dysarthric speakers, we investigate the usefulness of a model-based procedure for reducing the number of items. We propose a mixed cumulative logit model, which is known in the psychometrics literature as the graded response model: responses ...
Kelemen Adám A AA Medicinal Chemistry Research Group, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Magyar Tudósok Körútja 2, Budapest, 1117, - - 2014
A physicochemical property-based desirability scoring scheme for fragment-based drug discovery was developed for class A aminergic GPCR targeted fragment libraries. Physicochemical property distributions of known aminergic GPCR-active fragments from the ChEMBL database were examined and used for a desirability function-based score. Property-distributions such as log D (at pH 7.4), PSA, pKa ...
Li Meili M School of Science, Donghua University, Shanghai, 201620, China, - - 2014
A network epidemic SIWR model for cholera and other diseases that can be transmitted via the environment is developed and analyzed. The person-to-person contacts are modeled by a random contact network, and the contagious environment is modeled by an external node that connects to every individual. The model is adapted ...
Saleh M I MI Faculty of Pharmacy, The University of Jordan, Amman, - - 2014
Introduction: The present analysis describes the longitudinal change in buprenorphine treatment outcome. It also examines several participant characteristics to predict response to buprenorphine. Methods: Participants (n=501, age>15 years) received buprenorphine/naloxone treatment for 4 weeks, and then were randomly assigned to undergo dose tapering over either 7 days or 28 days. ...
Musoro Jammbe Z - - 2014
In prognostic studies, the lasso technique is attractive since it improves the quality of predictions by shrinking regression coefficients, compared to predictions based on a model fitted via unpenalized maximum likelihood. Since some coefficients are set to zero, parsimony is achieved as well. It is unclear whether the performance of ...
Kraemer Helena Chmura HC Department of Psychiatry and Behavioral Sciences, Stanford University (Emerita), Palo Alto, CA - - 2014
Does the McFarlane et al study(1) provide a model for practical trials? Unfortunately, not. The methodological problems are here reviewed and used as a springboard to set out methodological criteria that might define such a model.
Mavridis Dimitris D Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece; Department of Primary Education, University of Ioannina, Ioannina, - - 2014
Copas and Shi suggested a selection model to explore the potential impact of publication bias via sensitivity analysis based on assumptions for the probability of publication of trials conditional on the precision of their results. Chootrakool et al. extended this model to three-arm trials but did not fully account for ...
Barker Richard J RJ Department of Mathematics and Statistics, University of Otago, P.O. Box 56, Dunedin 9016, New - - 2014
Motivated by field sampling of DNA fragments, we describe a general model for capture-recapture modeling of samples drawn one at a time in continuous-time. Our model is based on Poisson sampling where the sampling time may be unobserved. We show that previously described models correspond to partial likelihoods from our ...
McGill Ryan J - - 2014
This study is an examination of the incremental validity of Cattell-Horn-Carroll (CHC) broad clusters from the Woodcock-Johnson III Tests of Cognitive Abilities (WJ III COG) for predicting scores on the Woodcock-Johnson III Tests of Achievement (WJ III ACH). The participants were children and adolescents, ages 6-18 (n = 4,722), drawn ...
McCarthy Ian M IM Department of Economics, Emory University Atlanta, GA, - - 2014
When analyzing many health-related quality-of-life (HRQoL) outcomes, statistical inference is often based on the summary score formed by combining the individual domains of the HRQoL profile into a single measure. Through a series of Monte Carlo simulations, this paper illustrates that reliance solely on the summary score may lead to ...
Illner Katrin K Institute of Computational Biology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany; and Institute for Mathematical Sciences. Technische Universität München , Munich, Germany - - 2014
Abstract In biology, more and more information about the interactions in regulatory systems becomes accessible, and this often leads to prior knowledge for recent data interpretations. In this work we focus on multivariate signaling data, where the structure of the data is induced by a known regulatory network. To extract ...
Andersen Nina Bjerre - - 2014
Reflection, the ability to examine critically one's own learning and functioning, is considered important for 'the good doctor'. The Groningen Reflection Ability Scale (GRAS) is an instrument measuring student reflection, which has not yet been validated beyond the original Dutch study. The aim of this study was to adapt GRAS ...
Torres Orlando O 1 Department of Medicine, Baystate Medical Center/Tufts University School of Medicine , Springfield, - - 2014
Abstract In the chronic care model, a missed appointment decreases continuity, adversely affects practice efficiency, and can harm quality of care. The aim of this study was to identify predictors of a missed appointment and develop a model to predict an individual's likelihood of missing an appointment. The research team ...
Laurent David A Burckett-St DA From the *Department of Anesthesia and Pain Management, and †Temerty/Chang International Centre for Telesimulation and Innovation in Medical Education, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada; and ‡Department of Anesthesiology and Perioperative Medicine, Queen's University, Kingston, Ontario, - - 2014
The purpose of this study was to establish construct and concurrent validity and interrater reliability of an assessment tool for ultrasound-guided regional anesthesia (UGRA) performance on a high-fidelity simulation model. Twenty participants were evaluated using a Checklist and Global Rating Scale designed for assessing any UGRA block. The participants performed ...
Zhang Tao T West China school of public health, Sichuan University, Chengdu 610041, - - 2014
This paper proposes a new method, using Bayesian approach, to analyze time series data of infectious diseases which have both temporal and spatial variational structures. Standard ways to model heteroscedastic time series are the ARCH-type models. However, from an empirical standpoint, there is a need to include spatial effect into ...
Sukno Federico M - - 2014
We present a method for the automatic localization of facial landmarks that integrates nonrigid deformation with the ability to handle missing points. The algorithm generates sets of candidate locations from feature detectors and performs combinatorial search constrained by a flexible shape model. A key assumption of our approach is that ...
Narayanan Vairavan V Division of Neurosurgery, Department of Surgery, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia, - - 2014
Endoscopic base of skull surgery has been growing in acceptance in the recent past due to improvements in visualisation and micro instrumentation as well as the surgical maturing of early endoscopic skull base practitioners. Unfortunately, these demanding procedures have a steep learning curve. A physical simulation that is able to ...
Yoo Bum-Soo - - 2014
During the last few decades, as a part of effort to enhance natural human robot interaction (HRI), considerable research has been carried out to develop human-like gaze control. However, most studies did not consider hardware implementation, real-time processing, and the real environment, factors that should be taken into account to ...
Lerner E Brooke - - 2014
Abstract Introduction. Accuracy and effectiveness analyses of mass casualty triage systems are limited because there are no gold standard definitions for each of the triage categories. Until there is agreement on which patients should be identified by each triage category, it will be impossible to calculate sensitivity and specificity or ...
Li Tao T International Rice Research Institute, Los Baños, - - 2014
Predicting rice (Oryza sativa) productivity under future climates is important for global food security. Ecophysiological crop models in combination with climate model outputs are commonly used in yield prediction, but uncertainties associated with crop models remain largely unquantified. We evaluated 13 rice models against multi-year experimental yield data at four ...
Yu Yi-Kuo YK National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA, Center for Human Genetics Research and Department of Biomedical Informatics, Vanderbilt University, Nashville, TN 37232, USA and currently at Janssen Research & Development, LLC, Spring House, PA 19477, - - 2014
DNA and protein patterns are usefully represented by sequence logos. However, the methods for logo generation in common use lack a proper statistical basis, and are non-optimal for recognizing functionally relevant alignment columns. We redefine the information at a logo position as a per-observation multiple-alignment log-odds score. Such scores are ...
Dimitrova Elena E Department of Mathematical Sciences, Clemson University, Clemson, SC, 29634, - - 2014
Identification of models of gene regulatory networks is sensitive to the amount of data used as input. Considering the substantial costs in conducting experiments, it is of value to have an estimate of the amount of data required to infer the network structure. To minimize wasted resources, it is also ...
Takashima Kazuto K Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu-ku, Kitakyushu, 808-0196, Japan; RIKEN RTC, 2271-130 Anagahora, Shimoshidami, Moriyama-ku, Nagoya, 463-0003, Japan. Electronic address: - - 2014
We have developed a computer-based system to simulate a guidewire in blood vessels for surgical planning, intra-operative assistance, and to facilitate the design of new guidewires. In this study, we compared simulation results with experimental results for validation of the simulation system. First, we inserted a commercial guidewire into a ...
Vafi Kourosh - - 2014
Scientific models are ideally reproducible, with results that converge despite varying methods. In practice, divergence between models often remains due to varied assumptions, incompleteness, or simply because of avoidable flaws. We examine LCA greenhouse gas (GHG) emissions models to test the reproducibility of their estimates for well-to-refinery inlet gate (WTR) ...
Ibrahim George M GM Division of Neurosurgery, St. Michael's Hospital, Labatt Family Centre of Excellence in Brain Injury and Trauma Research, Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, Ontario, Canada Department of Surgery, University of Toronto, Toronto, Ontario, - - 2014
Network analysis is an emerging tool for the study of complex systems. In the current report, the cascade of physiological and neurological changes following aneurysmal subarachnoid haemorrhage (SAH) was modelled as a complex system of interacting parameters. Graph theoretical analysis was then applied to identify parameters at critical topological junctions ...
Bentley Alison R AR The John Bingham Laboratory, NIAB, Huntingdon Road, Cambridge, CB3 0LE, UK, - - 2014
We show the application of association mapping and genomic selection for key breeding targets using a large panel of elite winter wheat varieties and a large volume of agronomic data. The heightening urgency to increase wheat production in line with the needs of a growing population, and in the face ...
Panwar Bharat - - 2014
In past number of methods have been developed for predicting post-translational modifications in proteins. In contrast, limited attempt has been made to understand post-transcriptional modifications. Recently it has been shown that tRNA modifications play direct role in the genome structure and codon usage. This study is an attempt to understand ...
Garcia E E Centre for Herd-oriented Education, Research and Development (HERD), Department of Large Animal Sciences, Grønnegaardsvej 2, DK-1870; Department of Food Science, Spectroscopy and Chemometrics, Rolighedsvej 30, DK-1958, University of Copenhagen, Frederiksberg C, Denmark. Electronic address: - - 2014
Lameness is prevalent in dairy herds. It causes decreased animal welfare and leads to higher production costs. This study explored data from an automatic milking system (AMS) to model on-farm gait scoring from a commercial farm. A total of 88 cows were gait scored once per week, for 2 5-wk ...
Wang Ning - - 2014
Novel constructive and destructive parsimonious extreme learning machines (CP- and DP-ELM) are proposed in this paper. By virtue of the proposed ELMs, parsimonious structure and excellent generalization of multiinput-multioutput single hidden-layer feedforward networks (SLFNs) are obtained. The proposed ELMs are developed by innovative decomposition of the recursive orthogonal least squares ...
Zhang Hai-Tao - - 2014
A fastest consensus problem of topology fixed networks has been formulated as an optimal linear iteration problem and efficiently solved in the literature. Considering a kind of predictive mechanism, we show that the consensus evolution can be further accelerated while physically maintaining the network topology. The underlying mechanism is that ...
Li Ying - - 2014
Tracking a target in infrared (IR) sequences is a challenging task because of low resolution, low signal-to-noise ratios, occlusion, and poor target visibility. For many civil and military applications, the real-time requirement is always a key factor for tracking algorithms to be used. This undoubtedly makes tracking in IR sequences ...
Choi Se Young SY Department of Urology, Chung-Ang University Hospital, Seoul, - - 2014
This study aimed to confirm the utility of the European Organization for Research and Treatment of Cancer (EORTC) and the Spanish Urological Club for Oncological Treatment (CUETO) scoring systems and to determine which model is preferred as a prognostic model in Korean patients with non-muscle-invasive bladder cancer. Between 1985 and ...
Benedict Matthew N MN Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of - - 2014
Genome-scale metabolic models provide a powerful means to harness information from genomes to deepen biological insights. With exponentially increasing sequencing capacity, there is an enormous need for automated reconstruction techniques that can provide more accurate models in a short time frame. Current methods for automated metabolic network reconstruction rely on ...
Tsai Miao-Yu MY Institute of Statistics and Information Science, National Changhua University of Education, Changhua, 500, - - 2014
The problem of variable selection in the generalized linear-mixed models (GLMMs) is pervasive in statistical practice. For the purpose of variable selection, many methodologies for determining the best subset of explanatory variables currently exist according to the model complexity and differences between applications. In this paper, we develop a "higher ...
Huo Yan Y Graduate School of Education, Rutgers, The State University of New Jersey, New Brunswick, NJ, USA, - - 2014
The present paper proposes a hierarchical, multi-unidimensional two-parameter logistic item response theory (2PL-MUIRT) model extended for a large number of groups. The proposed model was motivated by a large-scale integrative data analysis (IDA) study which combined data (N = 24,336) from 24 independent alcohol intervention studies. IDA projects face unique ...
Stanton Jessica C JC Department of Ecology and Evolution, Stony Brook University, Stony Brook, NY, 11794, - - 2014
Climate change is likely to become an increasingly major obstacle to slowing the rate of species extinctions. Several new assessment approaches have been proposed for identifying climate-vulnerable species, based on the assumption that established systems such as the IUCN Red List need revising or replacing because they were not developed ...
Dong Fengxia F Department of Agricultural and Applied Economics, University of Wisconsin-Madison, 427 Lorch Street, Madison, WI 53706, USA. Electronic address: - - 2014
Measuring farm sustainability performance is a crucial component for improving agricultural sustainability. While extensive assessments and indicators exist that reflect the different facets of agricultural sustainability, because of the relatively large number of measures and interactions among them, a composite indicator that integrates and aggregates over all variables is particularly ...
Debanne T T Laboratory CIAMS, University Paris-Sud Orsay, Orsay, - - 2014
This study was based on the naturalistic decision-making paradigm and regulatory focus theory. Its aim was to model coaches' decision-making processes for handball teams' defensive systems based on relevant cues of the reward structure, and to determine the weight of each of these cues. We collected raw data by video-recording ...
Dellicour Simon S Evolutionary Biology and Ecology, Université Libre de Bruxelles, av. FD Roosevelt 50, 1050 Brussels, Belgium Present address: Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom - - 2014
Computer simulations of genetic data are increasingly used to investigate the impact of complex historical scenarios on patterns of genetic variation. Yet, in most empirical studies, relatively large portions of species ranges are often treated as panmictic populations, ignoring the underlying spatial context. In some cases, however, a more accurate ...
Bottesi Gioia G a Department of General Psychology , University of Padua , Padua , - - 2014
Questionnaires generate numerical scores, but endorsing different sets of items could produce the same score despite reflecting qualitatively different configurations of clinical features. Formal psychological assessment (FPA) attempts to overcome this by identifying the clinical features entailed by observed response patterns. This study illustrates an application of FPA to the ...
Kalantari Zahra Z Department of Land and Water Resources, Royal Institute of Technology/KTH, SE-10044 Stockholm, Sweden; Department of Physical Geography and Quaternary Geology, Stockholm University, SE-106 91 Stockholm, Sweden. Electronic address: - - 2014
Identifying a 'best' performing hydrologic model in a practical sense is difficult due to the potential influences of modeller subjectivity on, for example, calibration procedure and parameter selection. This is especially true for model applications at the event scale where the prevailing catchment conditions can have a strong impact on ...
Kim Seon-Ha - - 2014
BackgroundThere is no research on mapping algorithms between EQ-5D and SF-36 in Korea. The aim of this study was to derive a predictive model for converting the SF-36 health profile to the EQ-5D index using data from several studies.MethodsIndividual data (n¿=¿2211) were collected from three different studies and separated into ...
Quiroz Zaida C ZC Department of Statistics, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, - - 2014
The Northern Humboldt Current System (NHCS) is the world's most productive ecosystem in terms of fish. In particular, the Peruvian anchovy (Engraulis ringens) is the major prey of the main top predators, like seabirds, fish, humans, and other mammals. In this context, it is important to understand the dynamics of ...
Buzbas Erkan O EO Department of Biology, Stanford University, Stanford, CA 94305-5020, USA; Department of Statistical Science, University of Idaho, Moscow, ID 84844-1104, USA. Electronic address: - - 2014
Approximate Bayesian computation (ABC) methods perform inference on model-specific parameters of mechanistically motivated parametric models when evaluating likelihoods is difficult. Central to the success of ABC methods, which have been used frequently in biology, is computationally inexpensive simulation of data sets from the parametric model of interest. However, when simulating ...
Frone Michael R - - 2014
This study develops and tests a new conceptual model of perceived physical availability of alcohol at work that provides unique insight into 3 dimensions of workplace physical availability of alcohol and their direct and indirect relations to workplace alcohol use and impairment. Data were obtained from a national probability sample ...
Hasegawa Takanori T 1 Bioinformatics Center, Institute for Chemical Research, Kyoto University , Gokasho, Uji, Kyoto, Japan - - 2014
Abstract Gene regulatory networks (GRNs) play a central role in sustaining complex biological systems in cells. Although we can construct GRNs by integrating biological interactions that have been recorded in literature, they can include suspicious data and a lack of information. Therefore, there has been an urgent need for an ...
Litterman Nadia K - - 2014
In a decade with over half a billion dollars of investment, more than 300 chemical probes have been identified to have biological activity through NIH funded screening efforts. We have collected the evaluations of an experienced medicinal chemist on the likely chemistry quality of these probes based on a number ...
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