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Results 451 - 500 of 1870
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Jalali Ali - - 2011
OBJECTIVE: In this paper a new nonlinear system identification approach is developed for dynamical quantification of cardiovascular regulation. This approach is specifically focused on the identification of the heart rate (HR) baroreflex mechanism. The principal objective of this paper is to improve the model accuracy in the estimation of HR ...
Cellai Davide - - 2011
Glass-forming liquids have been extensively studied in recent decades, but there is still no theory that fully describes these systems, and the diversity of treatments is in itself a barrier to understanding. Here we introduce a new simple model that (possessing both liquid-crystal and glass transition) unifies different approaches, producing ...
Arkin Adam P - - 2011
A decade ago, seminal perspectives and papers set a strong vision for the field of systems biology, and a number of these themes have flourished. Here, we describe key technologies and insights that have elucidated the evolution, architecture, and function of cellular networks, ultimately leading to the first predictive genome-scale ...
Peterfreund Robert A - - 2011
Background: Efforts to assure high-quality, safe, clinical care depend upon capturing information about near-miss and adverse outcome events. Inconsistent or unreliable information capture, especially for infrequent events, compromises attempts to analyze events in quantitative terms, understand their implications, and assess corrective efforts. To enhance reporting, we developed a secure, electronic, ...
Ritter James A - - 2011
A new model has been developed for predicting mixed-gas adsorption equilibria from multicomponent gas mixtures based on the dual-process Langmuir (DPL) formulation. It predicts ideal, nonideal, and azeotropic adsorbed solution behavior from a knowledge of only single-component adsorption isotherms and the assertion that each binary pair in the gas mixture ...
Lin Hsueh-Chun - - 2011
The groundwater level represents a critical factor to evaluate hillside landslides. A monitoring system upon the real-time prediction platform with online analytical functions is important to forecast the groundwater level due to instantaneously monitored data when the heavy precipitation raises the groundwater level under the hillslope and causes instability. This ...
Culmer P R - - 2011
We developed a system for quantitatively measuring arm movement. Our approach provides a method to simultaneously capture upper limb kinetic and kinematic data during assisted passive arm movements. Data are analysed with respect to Cartesian and upper limb coordinate systems to obtain upper limb joint angles and torques. We undertook ...
Bogdan Crenguţa M - - 2011
The goal of using virtual and augmented reality technologies in therapeutic interventions simulation, in the fixed prosthodontics (VirDenT) project, is to increase the quality of the educational process in dental faculties, by assisting students in learning how to prepare teeth for all-ceramic restorations. Its main component is an e-learning virtual ...
Kellie-Smith Owen - - 2011
Global CO(2) emissions are understood to be the largest contributor to anthropogenic climate change, and have, to date, been highly correlated with economic output. However, there is likely to be a negative feedback between climate change and human wealth: economic growth is typically associated with an increase in CO(2) emissions ...
Uchiyama Takanori - - 2011
A mechanomyogram (MMG) from single motor units of the anconeus muscle in voluntary isometric contraction was recorded from seven subjects using a spike-triggered averaging technique. The MMG system, in which the input was an ideal impulse and the output was the MMG detected with an acceleration sensor, was identified as ...
Levitin Gregory - - 2011
The article considers the optimal resource distribution in a parallel system between increasing protection and providing redundancy in a situation when the attacker's and defender's resources are stockpiling and the resource increment rate is constant. It is assumed that the system must perform within an exogenously given time horizon and ...
Marder Eve E Department of Biology and Volen Center, Brandeis University, Waltham, MA 02454, USA. - - 2011
I summarize recent computational and experimental work that addresses the inherent variability in the synaptic and intrinsic conductances in normal healthy brains and shows that multiple solutions (sets of parameters) can produce similar circuit performance. I then discuss a number of issues raised by this observation, such as which parameter ...
Serino C A - - 2011
We introduce a new model for an earthquake fault system that is composed of noninteracting simple lattice models with different levels of damage denoted by q. The undamaged lattice models (q=0) have Gutenberg-Richter scaling with a cumulative exponent β=1/2, whereas the damaged models do not have well defined scaling. However, ...
Lee Yun Y The Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech and Emory University, Atlanta, GA 30332-0535, United - - 2011
Operating principles address general questions regarding the response dynamics of biological systems as we observe or hypothesize them, in comparison to a priori equally valid alternatives. In analogy to design principles, the question arises: Why are some operating strategies encountered more frequently than others and in what sense might they ...
Erguler Kamil K Centre for Bioinformatics, Imperial College London, UK. - - 2011
The size and complexity of cellular systems make building predictive models an extremely difficult task. In principle dynamical time-course data can be used to elucidate the structure of the underlying molecular mechanisms, but a central and recurring problem is that many and very different models can be fitted to experimental ...
Siristatidis Charalampos - - 2011
Predicting the outcome of in-vitro fertilization (IVF) treatment is an extremely semantic issue in reproductive medicine. Discrepancies in results among reproductive centres still exist making the construction of new systems capable to foresee the desired outcome a necessity. As such, artificial neural networks (ANNs) represent a combination of a learning, ...
Stachowicz Anna - - 2011
Charge sensitivity analysis (CSA) was extended to AMBER force-field resolution. The effective electronegativity and hardness data were found using evolutionary algorithms. Four model hardness matrices based on the classical electrostatic, Mataga-Nishimoto, Ohno, and Louwen-Vogt interpolation formulae were considered. Mulliken population analysis and electrostatically derived charges (CHELPG) were taken into account. ...
Zio Enrico - - 2011
In this work, specific indicators are used to characterize the criticality of components in a network system with respect to their contribution to failure cascade processes. A realistic-size network is considered as reference case study. Three different models of cascading failures are analyzed, differing both on the failure load distribution ...
Kennedy R R - - 2011
We have developed and deployed within our operating rooms a system which provides real-time estimates of effect-site levels of inhalational anaesthetic agents along with forward predictions of end-tidal and effect-site concentrations. The initial aim of this project was to provide users of inhalational agents with tools similar to those available ...
Zhang Xuekui - - 2011
Summary ChIP-seq combines chromatin immunoprecipitation with massively parallel short-read sequencing. While it can profile genome-wide in vivo transcription factor-DNA association with higher sensitivity, specificity, and spatial resolution than ChIP-chip, it poses new challenges for statistical analysis that derive from the complexity of the biological systems characterized and from variability and ...
Lee Aline Magdalena - - 2011
Abstract Demographic stochasticity has a substantial influence on the growth of small populations and consequently on their extinction risk. Mating system is one of several population characteristics that may affect this. We use a stochastic pair-formation model to investigate the combined effects of mating system, sex ratio, and population size ...
Sanders Joan E JE University of Washington, Seattle, WA 98195, USA. - - 2011
It is estimated that only 24% of practitioners use CAD/CAM regularly. Socket manufacturing error may be a source of the limited use of central fabrication. The purpose of this study was to investigate the differences in shape between computer-manufactured, centrally fabricated carved models and electronic file shapes, to determine if ...
Dai Chaohua - - 2011
Time-delay chaotic systems have some very interesting properties, and their parameter estimation has received increasing interest in the recent years. It is well known that parameter estimation of a chaotic system is a nonlinear, multivariable, and multimodal optimization problem for which global optimization techniques are required in order to avoid ...
Medina Yliana Rojas - - 2011
A national hospital-based nonfatal road traffic injury surveillance system was established at sentinel units across Peru in 2007 under the leadership of the Ministry of Health. Surveillance data are drawn from three different sources (hospital records, police reports, and vehicle insurance reports) and include nonfatal road traffic injuries initially attended ...
Bogner Viktoria - - 2011
Oligonucleotide microarray technology has been developed to a very powerful and favorable biotechnique. However, it is an explicit challenge to judge the potential biological meaning of such extensive amounts of data. There are various-commercially available or free-software applications for pathway analyses on microarray data on the market. The aim of ...
Wierts Roel - - 2011
RATIONALE: A new system is presented and evaluated for real-time monitoring of blood leakage during hyperthermic isolated limb perfusion (HILP) surgery, the Veenstra HILP system. This system incorporates two software models to determine blood leakage: a single-nuclide algorithm and a newly developed dual-nuclide algorithm. The latter algorithm has the advantage ...
Branković Saša - - 2011
The stereotyped nature of the skin conductance response (SCR) waveform has recently inspired several dynamic modeling approaches to the process of SCR. The suggested models differ: (i) in the order of the linear differential equation representing the process, and (ii) the neurobiological interpretation of the system parameters. While several research ...
Jang Richard - - 2011
Abstract In NMR resonance assignment, an indispensable step in NMR protein studies, manually processed peaks from both N-labeled and C-labeled spectra are typically used as inputs. However, the use of homologous structures can allow one to use only N-labeled NMR data and avoid the added expense of using C-labeled data. ...
Wang Pei P Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, - - 2011
Genomic instability, the propensity of aberrations in chromosomes, plays a critical role in the development of many diseases. High throughput genotyping experiments have been performed to study genomic instability in diseases. The output of such experiments can be summarized as high-dimensional binary vectors, where each binary variable records aberration status ...
Lee Myung Kyung - - 2011
Sharing of cancer-related information among healthcare professionals is crucial to ensuring the quality of long-term care for cancer survivors. Appropriate distribution of the essential facts can be achieved using data models. The purpose of this study was to develop and validate suitable data models for use in the nursing assessment ...
Gordon J D - - 2011
To evaluate the robustness of TG119-based quality assurance metrics for an IMRT system. Four planners constructed treatment plans for the five IMRT test cases described in TG119. All plans were delivered to a 30 cm x 30 cm x 15 cm solid water phantom in one treatment session in order ...
- - 2011
[This corrects the article on p. 478 in vol. 54, PMID: 21189893.][This corrects the article on p. 52 in vol. 54, PMID: 20532074.].
Dinakarababu D V - - 2011
Spectroscopic chemical classification based on adaptive, feature-specific measurements has been implemented and demonstrated to provide significant performance gain over traditional systems. The measurement scheme and the decision model are discussed. A prototype system with a digital micro-mirror device as the adaptive element has been constructed and validates the theoretical findings ...
De Wilde Philippe - - 2011
A multiagent system is a distributed system where the agents or nodes perform complex functions that cannot be written down in analytic form. Multiagent systems are highly connected, and the information they contain is mostly stored in the connections. When agents update their state, they take into account the state ...
Oka Kunihiro - - 2011
BACKGROUND: We developed an original computer program that three-dimensionally simulates anatomical deformity correction of an extremity based on computed tomography (CT) data and an operative method that uses a custom-designed surgical device to realize the simulation. The purpose of this study was to investigate the feasibility and accuracy of this ...
Chand Dhan - - 2011
Inhibition of reproductive function by the activation of the stress-response has been observed since times of antiquity, however delineating a molecular mechanism by which this occurs in vertebrates continues to present a major challenge. Because recent genome sequencing programs have identified the presence of numerous paralogous peptides and receptors, our ...
Klingbeil Guido - - 2011
MOTIVATION: The importance of stochasticity in biological systems is becoming increasingly recognised and the computational cost of biologically realistic stochastic simulations urgently requires development of efficient software. We present a new software tool STOCHSIMGPU which exploits graphics processing units (GPUs) for parallel stochastic simulations of biological/chemical reaction systems and show ...
Husek Petr - - 2011
This paper deals with the linear systems with uncertain parameters described by fuzzy numbers. The problem of determining the stability margin of those systems with linear affine dependence of the coefficients of a characteristic polynomial on system parameters is studied. Fuzzy numbers describing the system parameters are allowed to be ...
Greenberg Steven A - - 2011
Citation is a powerful method for establishing belief. Published statements gain credibility when followed by citations. Citation in its purest form consists of the scholarly connection of authors' ideas and claims to existing literature, yet there are also non-scholarly uses of citation that are best called citation distortions. Unfounded biomedical ...
Shelley Cameron - - 2011
This paper addresses an important multi-disciplinary issue of current interest, that is, the implications of technological design for fairness. A visual, graphical methodology centered on the Taylor-Russell diagram is proposed to address this issue. The Taylor-Russell diagram helps to identify and explore ways in which predictions built into designs can ...
Rosenling Therese - - 2011
Multiple sclerosis (MScl) is defined by central nervous system (CNS) inflammation, demyelination and axonal damage. Some of the disease mechanisms are known but the cause of this complex disorder stays an enigma. Experimental autoimmune encephalomyelitis (EAE) is an animal model mimicking many aspects of MScl. This review aims to provide ...
Artemova Svetlana - - 2011
A number of modeling and simulation algorithms using internal coordinates rely on hierarchical representations of molecular systems. Given the potentially complex topologies of molecular systems, though, automatically generating such hierarchical decompositions may be difficult. In this article, we present a fast general algorithm for the complete construction of a hierarchical ...
Wu C L - - 2011
There has been an increasing interest in the use of upper-room ultraviolet germicidal irradiation (UVGI) system because of its proven disinfection effect for airborne microorganisms. To better design and explore further potential applications of UVGI systems, it is of critical importance to predict the spatial UV intensity in enclosures. In ...
Mollica G - - 2011
The dynamic behavior of three completely amorphous ethylene-propylene random copolymers with slightly different structural properties was investigated by means of a multifrequency global fitting approach, presented in a previous paper. To this end, the trends of NMR (1)H and (13)C spin-lattice relaxation times with temperature, obtained at different frequencies, were ...
Xu Zhenli - - 2011
We have developed a treecode-based O(Nlog N) algorithm for the generalized Born (GB) implicit solvation model. Our treecode-based GB (tGB) is based on the GBr6 [J. Phys. Chem. B 111, 3055 (2007)], an analytical GB method with a pairwise descreening approximation for the R6 volume integral expression. The algorithm is composed ...
Salvado Baldiri - - 2011
Most aspects of molecular biology can be understood in terms of biological design principles. These principles can be loosely defined as qualitative and quantitative features that emerge in evolution and recur more frequently than one would expect by chance alone in biological systems that perform a given type of process ...
Marín Laura - - 2011
Nurses play an important role in the multidisciplinary management of inflammatory bowel disease (IBD), but little is known about this role and the associated resources. To improve knowledge of resource availability for health care activities and the different organizational models in managing IBD in Spain. Cross-sectional study with data obtained ...
Baraniuk Richard G - - 2011
The data deluge is changing the operating environment of many sensing systems from data-poor to data-rich--so data-rich that we are in jeopardy of being overwhelmed. Managing and exploiting the data deluge require a reinvention of sensor system design and signal processing theory. The potential pay-offs are huge, as the resulting ...
Maryasin Boris - - 2011
Selected theoretical methods, basis sets and solvation models have been tested in their ability to predict (31)P NMR chemical shifts of large phosphorous-containing molecular systems in solution. The most efficient strategy was found to involve NMR shift calculations at the GIAO-MPW1K/6-311++G(2d,2p)//MPW1K/6-31G(d) level in combination with a dual solvation model including ...
Teichgräber Ulf K - - 2011
OJECTIVES: To eliminate non-value-adding (NVA) waste for the procurement of endovascular stents in interventional radiology services by applying value stream mapping (VSM). MATERIALS AND METHODS: The Lean manufacturing technique was used to analyze the process of material and information flow currently required to direct endovascular stents from external suppliers to ...
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