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Jing X X Xia Jing, Assistant Professor, NIH Clinical Center, National Institutes of Health, Street, Bethesda,MA, - - 2014
Objectives: Graphical displays can make data more understandable; however, large graphs can challenge human comprehension. We have previously described a filtering method to provide high-level summary views of large data sets. In this paper we demonstrate our method for setting and selecting thresholds to limit graph size while retaining important ...
Hsu Yung-Fong YF Department of Psychology, National Taiwan University, Taipei City, - - 2014
The study of thresholds for discriminability has been of long-standing interest in psychophysics. While threshold theories embrace the concept of discrete-state thresholds, signal detection theory discounts such a concept. In this paper we concern ourselves with the concept of thresholds from the discrete-state modelling viewpoint. In doing so, we find ...
Glick Joshua J Penn State Hershey Medical Center, Penn State College of Medicine, Hershey, - - 2014
Coordination of the tasks of performing chest compressions and defibrillation can lead to communication challenges that may prolong time spent off the chest. The purpose of this study was to determine whether defibrillation provided by the provider performing chest compressions led to a decrease in peri-shock pauses as compared to ...
Kempe René R Department of Biomedical Engineering, City College of the City University of New York, New York, NY 10031, USA. Department of Biomedical Engineering, Hamburg University of Applied Sciences, Hamburg, - - 2014
Objective. Research studies on transcranial electric stimulation, including direct current, often use a computational model to provide guidance on the placing of sponge-electrode pads. However, the expertise and computational resources needed for finite element modeling (FEM) make modeling impractical in a clinical setting. Our objective is to make the exploration ...
Wang Zhen Z Department of Physics, Hong Kong Baptist University, Kowloon Tong, Hong Kong; Center for Nonlinear Studies and Beijing-Hong Kong-Singapore Joint Center for Nonlinear and Complex systems, Institute of Computational and Theoretical Studies, Hong Kong Baptist University, Kowloon Tong, Hong - - 2014
Evolution of cooperation in the prisoner's dilemma and the public goods game is studied, where initially players belong to two independent structured populations. Simultaneously with the strategy evolution, players whose current utility exceeds a threshold are rewarded by an external link to a player belonging to the other population. Yet ...
Jahanmiri-Nezhad Faezeh F *Sensory Motor Performance Program, Rehabilitation Institute of Chicago, Illinois, U.S.A.; †Department of Bioengineering, University of Illinois, Chicago, Illinois, U.S.A.; ‡Department of Neurology, Medical College of Wisconsin, Milwaukee, Wisconsin, U.S.A.; §Department of Physical Medicine and Rehabilitation, Northwestern University, Chicago, Illinois, U.S.A.; and ‖Institute of Biomedical Engineering, University of Science and Technology of China, Hefei, - - 2014
Examination of spontaneous muscle activity is an important part of the routine electromyogram (EMG) in assessing neuromuscular diseases. The EMG is specifically valuable as a diagnostic test in supporting the diagnosis of amyotrophic lateral sclerosis. High-density surface EMG is a relatively new technique that has until now been used in ...
Cavanaugh Kyle C - - 2014
The manner in which patches are delineated in spatially realistic metapopulation models will influence the size, connectivity, and extinction and recolonization dynamics of those patches. Most commonly used patch-definition methods focus on identifying discrete, contiguous patches of habitat from a single temporal observation of species occurrence or from a model ...
Santos-Concejero Jordan J a UCT/MRC Research Unit for Exercise Science and Sports Medicine , University of Cape Town , Cape Town , South - - 2014
Abstract This study investigated the influence of the regression model and initial intensity during an incremental test on the relationship between the lactate threshold estimated by the maximal-deviation method and performance in elite-standard runners. Twenty-three well-trained runners completed a discontinuous incremental running test on a treadmill. Speed started at 9 ...
Chizhov A V AV A.F. Ioffe Physical-Technical Institute of the Russian Academy of Sciences, Politekhnicheskaya str., 26, 194021, Saint-Petersburg, Russia, - - 2014
Characteristics of action potential generation are important to understanding brain functioning and, thus, must be understood and modeled. It is still an open question what model can describe concurrently the phenomena of sharp spike shape, the spike threshold variability, and the divisive effect of shunting on the gain of frequency-current ...
Hirschfeld Gerrit G German Pediatric Pain Center, Children's Hospital, Dr.-Friedrich-Steiner Str. 5, 45711 Datteln, Germany; Children's Pain Therapy and Paediatric Palliative Care, Witten/Herdecke University, 45711 Datteln, Germany. Electronic address: - - 2014
Many diagnostic studies are aimed at defining "optimal" thresholds. Here, we evaluate the performance of empirically defined optimal thresholds (1) in the sample in which they were defined and (2) in the population from which the sample was drawn. We simulated test results for 120,000 samples varying the number of ...
Ashworth Allan A Atkins, Woodcote Grove, Ashley Road, Epsom, Surrey KT18 5BW, - - 2014
A new radioactive substances regulatory regime came into effect across the UK on 1 October 2011, accompanied by Government and regulator's guidance. The legislation sets new activity thresholds for what is within its scope and for what is exempt from the permitting requirements. These thresholds are, for the first time, ...
Rich Carly C Medical Research Centre of Epidemiology for Child Health, University College London, London, United - - 2014
Accelerometers are designed to measure plausible human activity, however extremely high count values (EHCV) have been recorded in large-scale studies. Using population data, we develop methodological principles for establishing an EHCV threshold, propose a threshold to define EHCV in the ActiGraph GT1M, determine occurrences of EHCV in a large-scale study, ...
Woo Choong-Wan CW Department of Psychology and Neuroscience, University of Colorado Boulder, USA; Institute of Cognitive Science, University of Colorado Boulder, - - 2014
Cluster-extent based thresholding is currently the most popular method for multiple comparisons correction of statistical maps in neuroimaging studies, due to its high sensitivity to weak and diffuse signals. However, cluster-extent based thresholding provides low spatial specificity; researchers can only infer that there is signal somewhere within a significant cluster ...
Dotu Ivan I Biology Department, Boston College, Chestnut Hill, Massachusetts, United States of - - 2014
We describe the first algorithm and software, RNAenn, to compute the partition function and minimum free energy secondary structure for RNA with respect to an extended nearest neighbor energy model. Our next-nearest-neighbor triplet energy model appears to lead to somewhat more cooperative folding than does the nearest neighbor energy model, ...
Plazas-Nossa Leonardo L Universidad Distrital Francisco José de Caldas, Facultad de Ingeniería, Bogotá, Colombia E-mail: lplazasn@udistrital.edu.co;plazas-l@javeriana.edu.co; Grupo de Investigación Ciencia e Ingeniería del Agua y el Ambiente, Facultad de Ingeniería, Pontificia Universidad Javeriana, Bogotá, - - 2014
The objective of this work is to introduce a forecasting method for UV-Vis spectrometry time series that combines principal component analysis (PCA) and discrete Fourier transform (DFT), and to compare the results obtained with those obtained by using DFT. Three time series for three different study sites were used: (i) ...
van Vugt Marieke K MK Department of Artificial Intelligence, University of Groningen, Groningen, The - - 2014
Many perceptual decision making models posit that participants accumulate noisy evidence over time to improve the accuracy of their decisions, and that in free response tasks, participants respond when the accumulated evidence reaches a decision threshold. Research on the neural correlates of these models' components focuses primarily on evidence accumulation. ...
Fakhouri A A Department of Electrical Engineering and Electronics, Ariel University, 40700 Ariel, - - 2014
The paper focuses on the quantitative analysis of Israeli Government's targets of 10% renewable energy penetration by 2020 and determining the desired methodology (models) for assessing the effects on the electricity market, addressing the fact that Israel is an electricity island. The main objective is to determine the influence of ...
Xu Jason J JJ Schulich School of Medicine & Dentistry, University of Western Ontario Clinical Skills Building, Room 3700, London, ON, N6A 5C1, - - 2013
Background: The threshold size required to detect lymphadenopathy via palpation has never been formally determined. This study sought to determine the threshold, sensitivity, and error of node palpation and how this changes with experience. Methods: Lymphadenopathy models were created using poly-vinyl alcohol cryogel to mimic tissue tactility. Node diameter ranged ...
Howe Andrew - - 2013
Algorithms to predict shock success based on VF waveform metrics could significantly enhance resuscitation by optimising the timing of defibrillation. To investigate robust methods of predicting defibrillation success in VF cardiac arrest patients, by using a support vector machine (SVM) optimisation approach. Frequency-domain (AMSA, dominant frequency and median frequency) and ...
Roberts James G - - 2013
Technological advances have allowed background-subtracted fast-scan cyclic voltammetry to emerge as a powerful tool for monitoring molecular fluctuations in living brain tissue; however, there has been little progress to date in advancing electrode calibration procedures. Variability in the performance of these handmade electrodes renders calibration necessary for accurate quantification; however, ...
Lampert Adam A Department of Environmental Science and Policy, University of California, Davis, CA, 95616, - - 2014
A variety of ecological systems around the world have been damaged in recent years, either by natural factors such as invasive species, storms and global change or by direct human activities such as overfishing and water pollution. Restoration of these systems to provide ecosystem services entails significant economic benefits. Thus, ...
Le-Nguyen Tuong-Vu - - 2013
A paper sliceform or lattice-style pop-up is a form of papercraft that uses two sets of parallel paper patches slotted together to make a foldable structure. The structure can be folded flat, as well as fully opened (popped-up) to make the two sets of patches orthogonal to each other. Automatic ...
Schramm Harrison C - - 2013
We develop an extension to differential equation models of dynamical systems to allow us to analyze probabilistic threshold dynamics that fundamentally and globally change system behavior. We apply our novel modeling approach to two cases of interest: a model of infectious disease modified for malware where a detection event drastically ...
Ekanadham Chaitanya - - 2013
Automatic identification of action potentials from one or more extracellular electrode recordings is generally achieved by clustering similar segments of the measured voltage trace, a method that fails (or requires substantial human intervention) for spikes whose waveforms overlap. We formulate the problem in terms of a simple probabilistic model, and ...
Hallett Rebecca H - - 2013
Recommended action thresholds for soybean aphid, Aphis glycines, do not adjust for natural enemy impact, although natural enemies contribute important biological control services. Because individual natural enemy species have varied impacts on pest population dynamics, incorporating the impact of a diverse predator guild into an action threshold can be cumbersome. ...
Revell Liam J - - 2013
Evolutionary biology is a study of life's history on Earth. In researching this history, biologists are often interested in attempting to reconstruct phenotypes for the long extinct ancestors of living species. Various methods have been developed to do this on a phylogeny from the data for extant taxa. In the ...
Shiffman C A - - 2013
A major problem confronting application of impedance techniques to studies of disease is the extraction of intrinsic properties of the tissue from the measured impedances, which unavoidably involve geometric factors as well. Amongst the foremost are the sizes and locations of the measuring electrode arrays, and this paper addresses one ...
Pascual-Ruiz Sara - - 2013
Tetranychus urticae is a key pest of citrus in Spain, especially of clementine mandarin trees. The effects of this mite on fruit production were assessed in 24 clementine trees for three consecutive years. Trees were visited weekly and spider mite and phytoseiid mite populations and leaf flush patterns were estimated. ...
Reid Cliff - - 2013
Fresh frozen cadavers are effective training models for airway management. We hypothesised that residual carbon dioxide (CO2) in cadaveric lung would be detectable using standard clinical monitoring systems, facilitating detection of tracheal tube placement and further enhancing the fidelity of clinical simulation using a cadaveric model. The tracheas of two ...
Wilkoff Bruce L - - 2013
While there are several hazards for patients with implanted pacemakers and defibrillators in the MRI environment, evaluation of lead electrode heating is the most complex because of the many influencing variables: patient size, anatomy, body composition, patient position in the bore, scan sequence (RF power level), lead routing, and lead ...
Gross William L - - 2013
Current methods for thresholding functional magnetic resonance imaging (fMRI) maps are based on the well-known hypothesis-test framework, optimal for addressing novel theoretical claims. However, these methods as typically practiced have a strong bias toward protecting the null hypothesis, and thus may not provide an optimal balance between specificity and sensitivity ...
Silk Daniel - - 2013
Abstract The likelihood-free sequential Approximate Bayesian Computation (ABC) algorithms are increasingly popular inference tools for complex biological models. Such algorithms proceed by constructing a succession of probability distributions over the parameter space conditional upon the simulated data lying in an ε-ball around the observed data, for decreasing values of the ...
Zhang J - - 2013
Sequence-based methods to delimit species are central to DNA taxonomy, microbial community surveys, and DNA meta-barcoding studies. Current approaches either rely on simple sequence similarity thresholds (OTU-picking) or on complex and compute-intensive evolutionary models. OTU-picking methods scale well on large data sets, but the results are highly sensitive to the ...
Stevens M Tynan R - - 2013
Many studies have investigated test-retest reliability of active voxel classification for fMRI, which is increasingly important for emerging clinical applications. The implicit impact of voxel-wise thresholding on this type of reliability has previously been under-appreciated. This has had two detrimental effects: 1) reliability studies use different fixed thresholds, making comparison ...
Inchauspe Adrián Angel AA Adrián Angel Inchauspe, Scientific Department, Argentina Acupuncture Society, Medical Sciences Faculty, La Plata University, La Plata, 1884 Buenos Aires, - - 2013
To introduce new applications into the ILCOR-cardiopulmonary resuscitation (CPR) "chain" sequence. Stages of the CPR sequence ("chain"): prior to the application of chest massage: assess the victim's state of consciousness and lung-heart failure; seek help (call 911), or in situations in which it is impossible to start the ILCOR protocol: ...
Singh P - - 2013
A classical model for social-influence-driven opinion change is the threshold model. Here we study cascades of opinion change driven by threshold model dynamics in the case where multiple initiators trigger the cascade, and where all nodes possess the same adoption threshold ϕ. Specifically, using empirical and stylized models of social ...
Scott Jonathan - - 2013
We describe the construction of a model of the electrode-electrolyte interface and surrounding electrolyte in the case of a platinum-electrode array intended for spinal-cord stimulation (SCS) application. We show that a finite, two-dimensional, resistor array provides a satisfactory model of the bulk electrolyte, and we identify the complexity required of ...
Choi Dong Gu - - 2013
Adoption of electric vehicles (EVs) would affect the costs and sources of electricity and the U.S. efficiency requirements for conventional vehicles (CVs). We model EV adoption scenarios in each of six regions of the Eastern Interconnection, containing 70% of the U.S. population. We develop electricity system optimization models at the ...
Röding Magnus - - 2013
One of the fundamental problems in the analysis of single particle tracking data is the detection of individual particle positions from microscopy images. Distinguishing true particles from noise with a minimum of false positives and false negatives is an important step that will have substantial impact on all further analysis ...
Barnes Taylor A - - 2013
Density functional theory (DFT) provides a formally exact framework for performing embedded subsystem electronic structure calculations, including DFT-in-DFT and wavefunction theory-in-DFT descriptions. In the interest of efficiency, it is desirable to truncate the atomic orbital basis set in which the subsystem calculation is performed, thus avoiding high-order scaling with respect ...
Rubenstein Donald S - - 2013
The Riata 1590 lead model contains both electrically active cables (AC) and filler cables (FC) that run in pairs within lumens along the lead body. FC are yet to be described as lead components that may be externalized from either external abrasion or inside-out abrasion seen in the recalled St. ...
Goy C B - - 2013
Abstract The ambulatory monitoring of biosignals involves the use of sensors, electrodes, actuators, processing tools and wireless communication modules. When a garment includes these elements with the purpose of recording vital signs and responding to specific situations it is call a 'Smart Wearable System'. Over the last years several authors ...
Neveln Izaak D - - 2013
Weakly electric knifefish have intrigued both biologists and engineers for decades with their unique electrosensory system and agile swimming mechanics. Study of these fish has resulted in models that illuminate the principles behind their electrosensory system and unique swimming abilities. These models have uncovered the mechanisms by which knifefish generate ...
Hsu Yung-Fong - - 2013
The family of (non-parametric, fixed-step-size) adaptive methods, also known as 'up-down' or 'staircase' methods, has been used extensively in psychophysical studies for threshold estimation. Extensions of adaptive methods to non-binary responses have also been proposed. An example is the three-category weighted up-down (WUD) method (Kaernbach, 2001) and its four-category extension ...
Holme Petter - - 2013
One of network epidemiology's central assumptions is that the contact structure over which infectious diseases propagate can be represented as a static network. However, contacts are highly dynamic, changing at many time scales. In this paper, we investigate conceptually simple methods to construct static graphs for network epidemiology from temporal ...
Kurita K - - 2013
We developed an effective non-contact technique for measuring human respiration using a nonattached electrode. The technique requires measurement of the current generated due to the difference in capacitance between a given electrode and the human body. The electrostatic induction current flowing through the electrode when placed a few centimeters from ...
Gao Liqiang - - 2013
Traditional automatic navigation methods for bio-robots are constrained to configured environments and thus can't be applied to tasks in unknown environments. With no consideration of bio-robot's own innate living ability and treating bio-robots in the same way as mechanical robots, those methods neglect the intelligence behavior of animals. This paper ...
Sue Andrian - - 2013
Most neural prostheses feature metallic electrodes to act as an interface between the device and the physiological tissue. When charge is injected through these electrodes, potentially harmful reactions may result. Others have developed finite element models to evaluate the performance of stimulating electrodes in vivo. Few however, model an electrode-electrolyte ...
Lee Won Hee - - 2013
We have proposed that the current amplitude in electroconvulsive therapy (ECT) be lowered to produce stimulation closer to the neural activation threshold and individualized to account for anatomical variability across patients. A novel approach to individualize the ECT current amplitude could be via motor threshold (MT) determination with transcranial electric ...
Opie N L - - 2013
To significantly increase the resolution achievable by a retinal prosthesis without requiring additional electrodes, a current steering technique could be utilized. In this study, a finite element model was constructed to analyze the local concentrations of charge carrying ions within a saline bath due to concurrent stimulation from two electrodes ...
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