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Gailani David D Division of Hematology/Oncology, Vanderbilt University, 777 Preston Research Building, 2220 Pierce Ave., Nashville, TN, 37232, USA, - - 2015
Evaluating anticoagulants in animal thrombosis models is a standard component of preclinical drug testing. Mice are frequently used for these initial evaluations because a variety of thrombosis models have been developed and are well characterized in this species, and the animals are relatively inexpensive to maintain. Because mice have a ...
Bortnowska Grażyna G Department of Food Technology, West Pomeranian University of Technology in Szczecin, Poland. Electronic address: - - 2014
The effects of pregelatinized potato starch concentration (PSC) ranged from 0 to 5wt% on the physical stability, color, rheological, textural, and sensory properties of model salad dressings prepared with 2wt% dried egg yolk (DEY) or sodium caseinate (SC) were explored. All dressings showed shear-thinning behavior with yield stress. Raising PSC ...
Gana Kamel K University of Bordeaux, France - - 2014
The aim of this study was to evaluate the predictive effects of infertility-related stress on psychological distress and marital satisfaction. Structural equation modeling was used to estimate a nonrecursive model hypothesizing the impact of infertility-related stress on both emotional distress and marital dissatisfaction, which were supposed to have a reciprocal ...
Hayashi Yoshihiro Y Department of Pharmaceutics, Hoshi - - 2014
A multivariate statistical technique was applied to clarify the causal correlation between variables in the manufacturing process and the residual stress distribution of tablets. Theophylline tablets were prepared according to a Box-Behnken design using the wet granulation method. Water amounts (X1), kneading time (X2), lubricant-mixing time (X3), and compression force ...
Song Mingzhi - - 2014
Lateral mass screw fixation (LSF) techniques have been widely used for reconstructing and stabilizing the cervical spine; however, complications may result depending on the choice of surgeon. There are only a few reports related to LSF applications, even though fracture fixation has become a severe complication. This study establishes the ...
Zimmermann Juliane J Center for Theoretical Biological Physics, Rice University, Houston, Texas. Electronic address: - - 2014
Cells migrate collectively during development, wound healing, and cancer metastasis. Recently, a method has been developed to recover intercellular stress in monolayers from measured traction forces upon the substrate. To calculate stress maps in two dimensions, the cell sheet was assumed to behave like an elastic material, and it remains ...
Kim Kwang Yoo KY *Department of Dentistry, Graduate School - - 2014
Summary OBJECTIVES: The aim of this study was to analyse the displacement and stress distribution in the maxillofacial complex during maxillary protraction with buccal and palatal plates using three-dimensional finite element analysis. Three anchorage appliance models-palatal plate (Type A), miniplate at the infrazygomatic crest (Type B), and conventional tooth-borne appliance ...
Ha Jh J Department of Conservative Dentistry, School of Dentistry, Kyungpook National University, Daegu, - - 2014
To examine the effect of several standard geometric characteristics of rotary instruments on the 'screw-in' forces and stresses generated on root dentine using 3D finite element analysis (FEA). Four cross-sectional designs (triangular, slender-rectangular, rectangular and square) were evaluated. The area of the triangular cross section and of the slender-rectangular model ...
Del Giudice M M Department of Psychology,University of New Mexico Logan Hall,University of New - - 2014
Stress experienced early in life exerts a powerful, lasting influence on development. Converging empirical findings show that stressful experiences become deeply embedded in the child's neurobiology, with an astonishing range of long-term effects on cognition, emotion, and behavior. In contrast with the prevailing view that such effects are the maladaptive ...
Zijlstra F R H FR Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The - - 2014
The concept of 'recovery' (from work) has quickly gained in importance in the occupational health literature. However, we think that the conceptualization of 'recovery' needs some more attention. Although many authors acknowledge that 'recovery' refers to a 'process', the concept is often treated as a static construct. In this paper, ...
Bostwick Joshua B JB Department of Engineering Science and Applied Mathematics, Northwestern University, Evanston, IL 60208, USA. - - 2014
A partially-wetting liquid can deform the underlying elastic substrate upon which it rests. This situation requires the development of theoretical models to describe the wetting forces imparted by the drop onto the solid substrate, particularly those at the contact-line. We construct a general solution using a displacement potential function for ...
Tuna Meral M Istanbul Technical University, Faculty of Mechanical Engineering, Istanbul, Turkey. Electronic address: - - 2014
Due to its significance in tooth movement, the stress/deformation field of periodontium and the alveolar bone remodeling process, periodontal ligament (PDL) cannot be excluded from the studies investigating dental biomechanics regarding its excessive deformability. Therefore, many analytical and numerical researches are carried out to simulate its response and to create ...
Clarke Samuel - - 2014
High-fidelity patient simulation has been praised for its ability to recreate lifelike training conditions. The degree to which high fidelity simulation elicits acute emotional and physiologic stress among participants - and the influence of acute stress on clinical performance in the simulation setting - remain areas of active exploration. We ...
Parker K J KJ Department of Electrical and Computer Engineering, University of Rochester, Hopeman Building 203, PO Box 270126, Rochester, NY, 14627-0126, - - 2014
A number of advances, including imaging of tissue displacements, have increased our ability to make measurements of tissue elastic properties of animal and human tissues. Accordingly, the question is increasingly asked, 'should our data be fit to a viscoelastic model, and if so which one?' In this paper we focus ...
Afkhami Michelle E ME Department of Evolution and Ecology, University of California, Davis One Shields Avenue, 2320 Storer Hall, Davis, CA, 95616, - - 2014
Understanding the processes determining species range limits is central to predicting species distributions under climate change. Projected future ranges are extrapolated from distribution models based on climate layers, and few models incorporate the effects of biotic interactions on species' distributions. Here, we show that a positive species interaction ameliorates abiotic ...
Kim Ho-Joong HJ Spine Center and Department of Orthopaedic Surgery, Seoul National University College of Medicine and Seoul National University Bundang Hospital, 166 Gumiro, Bundang-gu, Seongnam, 463-707, Republic of - - 2014
The presence of degeneration alters the stress within that particular degenerated disc. Therefore, the state of degeneration of the disc at the level adjacent to a single level fusion would influence the rate of subsequent further degeneration of that same adjacent disc. Therefore, the purpose of this study was to ...
Alekseychyk Larysa L Process & Product Development, Amgen, Inc., Seattle, WA, - - 2014
Selection of a suitable formulation that provides adequate product stability is an important aspect of the development of biopharmaceutical products. Stability of proteins includes not only resistance to chemical modifications but also conformational and colloidal stabilities. While chemical degradation of antibodies is relatively easy to detect and control, propensity for ...
Zhang J P JP College of Energy and Mechanical Engineering, Shanghai University of Electric Power, Shanghai, 200090, - - 2014
In order to accurately acquire the life time information for the organic light emitting diode (OLED), an experiment based on the normal stress life test was carried out to gain the data for the luminance degradation tests. The luminance degradation model of OLED was established based on the Weibull function ...
Chen Wen-Ming WM a Biomechanics Research Group, Department of Mechanical Engineering , University of Melbourne , Victoria 3010 , - - 2014
Many heel pathologies including plantar heel pain may result from micro tears/trauma in the subcutaneous tissues, in which internal tissue deformation/stresses within the heel pad play an important role. Previously, many finite element models have been proposed to evaluate stresses inside the heel pad, but the majority of these models ...
Yoganandan Narayan - - 2014
The study objective was to determine thorax and abdomen deflection-time corridors using the equal-stress equal-velocity approach from oblique side impact sled tests with post-mortem human surrogates fitted with chestbands. An anthropometry-specific modular and scalable load-wall design was used. Individual surrogate responses were normalized to standard mid-size male anthropometry. Corridors from ...
Baskett Marissa L ML Department of Environmental Science and Policy, University of California, Davis, California - - 2014
Abstract Community-level resilience depends on the interaction between multiple populations that vary in individual responses to disturbance. For example, in tropical reefs, some corals can survive higher stress (resistance) while others exhibit faster recovery (engineering resilience) following disturbances such as thermal stress. While each type will negatively affect the other ...
Robinson Jonathan L JL Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, - - 2014
Many pathogens depend on nitric oxide (NO) detoxification and repair to establish an infection, and inhibitors of these systems are under investigation as next-generation antibiotics. Because of the broad reactivity of NO and its derivatives with biomolecules, a deep understanding of how pathogens sense and respond to NO, as an ...
Anami Lilian Costa LC Department of Dental Materials and Prosthodontics, Institute of Science and Technology, UNESP - Univ Estadual Paulista, São José dos Campos, - - 2014
To evaluate the influence of the geometry and design of prosthetic crown preparations on stress distribution in compression tests, using finite element analysis (FEA). Six combinations of 3D drawings of all-ceramic crowns (yttria-stabilized zirconia framework and porcelain veneer) were evaluated: F, flat preparation and simplified crown; FC, flat preparation and ...
Jacobs Nathan T NT Department of Mechanical Engineering and Applied Mechanics, University of Pennsylvania, 229 Towne Building, 220 South 33rd Street, Philadelphia, PA 19104, United - - 2014
Finite element (FE) models are advantageous in the study of intervertebral disc mechanics as the stress-strain distributions can be determined throughout the tissue and the applied loading and material properties can be controlled and modified. However, the complicated nature of the disc presents a challenge in developing an accurate and ...
André Marie-Françoise MF Clermont Université, Université Blaise Pascal, GEOLAB, BP 10448, F-63000 Clermont-Ferrand, France; CNRS, UMR 6042, GEOLAB, F-63057 Clermont-Ferrand, France; Institut Universitaire de France, Paris, France. Electronic address: - - 2014
The present study provides the first quantitative assessment of the deteriorative impact of forest clearance on susceptible sandstone masonries. At Ta Keo, a 1000yr-old temple cleared of the Angkor forest in the early 20th century, GIS-based analysis of historic imagery indicates an average ten-fold increase in stone loss rates (0.2 ...
Joshi Gaurav V GV Department of Biomedical Materials Science, School of Dentistry, University of Mississippi Medical Center, Jackson, MS, United - - 2014
The objective of this study was to test the following hypotheses: (1) both cyclic degradation and stress-corrosion mechanisms result in subcritical crack growth (SCG) in a fluorapatite glass-ceramic (IPS e.max ZirPress, Ivoclar-Vivadent) and (2) there is an interactive effect of stress corrosion and cyclic fatigue to accelerate subcritical crack growth. ...
Mimura Koki K Tokyo University of Agriculture and Technology, Tokyo, - - 2014
Behaviour is one of the most powerful objective signals that connotes psychological functions regulated by neuronal network systems. This study searched for simple behaviours using smartphone sensors with three axes for measuring acceleration, angular speed and direction. We used quantitative analytic methodology of pattern recognition for work contexts, individual workers ...
Walters Robert H RH Pfizer, Pharmaceutical R&D - BioTherapeutics Pharmaceutical Sciences, Andover, Massachusetts, - - 2014
Drying is a commonly used technique for improving the product stability of biotherapeutics. Typically, drying is accomplished through freeze-drying, as evidenced by the availability of several lyophilized products on the market. There are, however, a number of drawbacks to lyophilization, including the lengthy process time required for drying, low energy ...
Sheng Shao-Yang SY College of Engineering, National Energy R & D Center for Non-food Biomass, China Agricultural University, PO Box 50, 17 Qinghua Donglu, Beijing 100083, - - 2014
The creep recovery, stress relaxation, temperature-dependence and their frequency-dependence of maize kernel were determined within a moisture content range of 11.9% to 25.9% (w/w) by using a dynamic mechanical analyzer. The 4-element Burgers model was found to adequately represent the creep behavior of the maize seeds (R(2)>0.97). The 5-element Maxwell ...
Fich Lars Brorson LB Department of Architecture, Design and Media Technology, Aalborg University, Østeraagade 6, DK-9000 Aalborg C, Denmark. Electronic address: - - 2014
Is has long been established, that views to natural scenes can a have a dampening effect on physiological stress rersponses. However, as people in Europe, Canada and North America today spent 50 - 85% of their time indoors, attention might also be paid to how the artificial man-made indoor environment ...
Ritchlin Christopher T CT From the Allergy, Immunology, and Rheumatology Division, Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York, USA.C.T. Ritchlin, MD, MPH, Professor of Medicine. - - 2014
The enthesis, attachment site of ligaments, tendons, and joint capsules to bone, has emerged as a complex structure or entheseal organ that dissipates stress to maintain homeostasis. Entheses are also anatomically and functionally integrated with adjacent bursa, fibrocartilage, and synovium in a synovial entheseal complex that may trigger inflammation in ...
Li Dan D The First Teaching Hospital, Jilin University, Changchun, Jilin 130021, P.R. - - 2014
Constructing models based on computed tomography images for finite element analysis (FEA) is challenging under pathological conditions. In the present study, an innovative method was introduced that uses Siemens syngo(®) 3D software for processing models and Mimics software for further modeling. Compared with the slice-by-slice traditional manual margin discrimination, the ...
He Qiang - - 2014
Since proposed two decades ago, the stress-gradient hypothesis (SGH), suggesting that species interactions shift from competition to facilitation with stress, has been widely examined. Despite broad support across species and ecosystems, ecologists debate whether the SGH applies to extreme environments, arguing that species interactions switch to competition or collapse under ...
Iguchi Akira A Okinawa National College of Technology,905 Henoko,Nago-City,Okinawa - - 2014
Summary Global warming (GW) and ocean acidification (OA) have been recognized as severe threats for reef-building corals that support coral reef ecosystems, but these effects on the early life history stage of corals are relatively unknown compared with the effects on calcification of adult corals. In this study, we evaluated ...
Xu Hongming H Department of Otolaryngology-Head and Neck Surgery, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, People's Republic of - - 2014
To evaluate vocal parameters after modified frontolateral partial laryngectomy (MFLPL) and frontolateral partial laryngectomy (FLPL) in both excised canine and finite element models. FLPL and MFLPL were compared, using a prospective paired case control laboratory study with excised canine larynx and computational modeling. Basic science study conducted in university laboratory. ...
Meardon Stacey A SA East Carolina University, Department of Physical Therapy, 2410E Health Sciences Building, Greenville, NC 27834, USA. Electronic address: - - 2014
Narrow step width has been linked to variables associated with tibial stress fracture. The purpose of this study was to evaluate the effect of step width on bone stresses using a standardized model of the tibia. 15 runners ran at their preferred 5k running velocity in three running conditions, preferred ...
Mumby Peter J PJ Marine Spatial Ecology Lab & ARC Centre of Excellence for Coral Reef Studies, School of Biological Sciences, University of Queensland, St Lucia, Qld 4072, Australia. Electronic address: - - 2014
Coral reefs are highly sensitive to the stress associated with greenhouse gas emissions, in particular ocean warming and acidification. While experiments show negative responses of most reef organisms to ocean warming, some autotrophs benefit from ocean acidification. Yet, we are uncertain of the response of coral reefs as systems. We ...
Sweeney J J IRC in Polymer Science and Technology, School of Engineering and Informatics, University of Bradford, Bradford BD7 1DP, UK. Electronic address: - - 2014
A multi-element constitutive model for a lactide-based shape memory polymer has been developed that represents loading to large tensile deformations, stress relaxation and stress recovery at 60, 65 and 70°C. The model consists of parallel Maxwell arms each comprising neo-Hookean and Eyring elements. Guiu-Pratt analysis of the stress relaxation curves ...
Abdul-Hameed H H Université Lille 1 Sciences et Technologies, Laboratoire de Mécanique de Lille (LML), UMR CNRS 8107, F-59650 Villeneuve d'Ascq, France. Electronic address: - - 2014
Polyethylene-based polymers as biomedical materials can contribute to a wide range of biomechanical applications. Therefore, it is important to identify, analyse, and predict with precision their mechanical behaviour. Polyethylene materials are semi-crystalline systems consisting of both amorphous and crystalline phases interacting in a rather complex manner. When the amorphous phase ...
Stadler Marc M Helmholtz Centre for Infection Research, Department Microbial Drugs, Inhoffenstrasse 7, 38124 Braunschweig, - - 2014
Although Xylaria hypoxylon is one of the most familiar fungi of temperate regions, the basionym of the name, Clavaria hypoxylon of Linnaeus, has remained untypified. Here we assess the original five elements included in the 1753 protologue; no candidate specimen was located but two illustrations Linnaeus cited were considered, one ...
Lopata Richard G P RG Cardiovascular Biomechanics, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands. Electronic address: - - 2014
Vascular elastography techniques are promising tools for mechanical characterization of diseased arteries. These techniques are usually validated with simulations or phantoms or by comparing results with histology or other imaging modalities. In the study described here, vascular elastography was applied to porcine aortas in vitro during inflation testing (n = 10) and results ...
Osman Zubaidah Jamil ZJ Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, - - 2014
The 21-item Depression, Anxiety and Stress Scale (DASS-21) is frequently used in non-clinical research to measure mental health factors among adults. However, previous studies have concluded that the 21 items are not stable for utilization among the adolescent population. Thus, the aims of this study are to examine the structure ...
Gong Zhiqiang - - 2014
This study compared the biomechanics of 3 fixation techniques: bilateral pedicle screw (BPS) fixation, unilateral pedicle screw (UPS) fixation, and UPS supplemented with translaminar facet screw (UPS+TLFS) fixation. The study was conducted in an L3-L5 finite element model. Three different finite element models were created by adopting different fixation techniques ...
Semenov M A MA Computational and Systems Biology Department, Rothamsted Research, Harpenden, Herts AL5 2JQ, - - 2014
Increasing cereal yield is needed to meet the projected increased demand for world food supply of about 70% by 2050. Sirius, a process-based model for wheat, was used to estimate yield potential for wheat ideotypes optimized for future climatic projections for ten wheat growing areas of Europe. It was predicted ...
Nishida Norihiro N Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755-8505, - - 2014
Cervical ossification of the posterior longitudinal ligament (OPLL) results in myelopathy. Conservative treatment is usually ineffective, thus, surgical treatment is required. One of the reasons for the poor surgical outcome following laminoplasty for cervical OPLL is kyphosis. In the present study, a 3-dimensional finite element method (3D-FEM) was used to ...
Prado Felippe Bevilacqua FB Department of Morphology, Anatomy Area, State University of Campinas, Av. Limeira, 901, P.O. Box 52 Piracicaba, SP, 13414-903, - - 2014
Empirical concepts describe the direction of the masticatory stress dissipation in the skull. The scientific evidence of the trajectories and the magnitude of stress dissipation can help in the diagnosis of the masticatory alterations and the planning of oral rehabilitation in the different areas of Dentistry. The Finite Element Analysis ...
Zhao Chuncheng C Second Department of Orthopedic, Baoji Centre Hospital, Baoji, 721008, Shannxi, China, - - 2014
The purpose of our study is to develop and validate three-dimensional finite element models of transforaminal lumbar interbody fusion, and explore the most appropriate method of fixation and fusion by comparing biomechanical characteristics of different fixation method. We developed four fusion models: bilateral pedicle screws fixation with a single cage ...
Campillo-Funollet Marc M Department of Restorative Dentistry, SUNY at Buffalo, Buffalo, NY, USA. Electronic address: - - 2014
The aim of this study is to explain the influence of peripheral interface stress singularities on the testing of tensile bond strength. The relationships between these theoretically predicted singularities and the effect of specimen size on the measured bond strength are evaluated. Finite element method (FEM) and boundary element method ...
Roberts Cynthia J CJ From the Department of Ophthalmology and Visual Science (Roberts), Department of Biomedical Engineering, The Ohio State University, Columbus, the Cole Eye Institute and Department of Biomedical Engineering (Dupps), Lerner Research Institute, Cleveland Clinic, and the Department of Biomedical Engineering (Dupps), Case Western Reserve University, Cleveland, Ohio, USA. Electronic address: - - 2014
Many algorithms exist for the topographic/tomographic detection of corneas at risk for post-refractive surgery ectasia. It is proposed that the reason for the difficulty in finding a universal screening tool based on corneal morphologic features is that curvature, elevation, and pachymetric changes are all secondary signs of keratoconus and post-refractive ...
Fu Y B YB Department of Mechanical Engineering, EA-04-06, Control and Mechatronics Lab 1, National University of Singapore, Singapore, Singapore. Electronic address: - - 2014
We hypothesize that both compression and elongation stress-strain data should be considered for modeling and simulation of soft tissue indentation. Uniaxial stress-strain data were obtained from in vitro loading experiments of porcine liver tissue. An axisymmetric finite element model was used to simulate liver tissue indentation with tissue material represented ...
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