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Alaa Nour Eddine - - 2014
Cardiac arrhythmias are becoming one of the major health care problem in the world, causing numerous serious disease conditions including stroke and sudden cardiac death. Furthermore, cardiac arrhythmias are intimately related to the signaling ability of cardiac cells, and are caused by signaling defects. Consequently, modeling the electrical activity of ...
Zhao Qi - - 2014
Bivalirudin is a direct thrombin inhibitor used in the cardiac intensive care unit when heparin is contraindicated due to heparin-induced thrombocytopenia. Since it is not a commonly used drug, clinical experience with its dosing is sparse. In earlier work ([1]) we developed a dynamic system model that accurately predicts the ...
Barbini Paolo - - 2014
Length-of-stay prediction for cardiac surgery patients is a key point for medical management issues, such as optimization of resources in intensive care units and operating room scheduling. Scoring systems are a very attractive family of predictive models, but their retraining and updating are generally critical. The present approach to designing ...
Castro Daniel - - 2014
Continuous follow-up of heart condition through long-term electrocardiogram monitoring is an invaluable tool for diagnosing some cardiac arrhythmias. In such context, providing tools for fast locating alterations of normal conduction patterns is mandatory and still remains an open issue. This work presents a real-time method for adaptive clustering QRS complexes ...
Moreira Gomes Johnny - - 2014
This paper compares different numerical methods for the solution of myocyte models of cardiac electrophysiology. In particular, it presents how the technique called Uniformization Method substantially increases the stability of simple first order methods such as Euler Explicit Method and Rush Larsen Method, for the solution of modern electrophysiology models ...
Sinha Ashish C AC Department of Anaesthesia, Drexel University College of Medicine, Philadelphia, PA, - - 2014
Aims and Objectives: Cardiac output (CO) measurement is essential for many therapeutic decisions in anesthesia and critical care. Most available non-invasive CO measuring methods have an invasive component. We investigate "pulse wave transit time" (estimated continuous cardiac output [esCCO]) a method of CO measurement that has no invasive component to ...
Wang Zhu Z Department of Research, Connecticut Children's Medical Center, Department of Pediatrics, University of Connecticut School of Medicine, Hartford, CT, - - 2014
This paper proposes a new statistical approach for predicting postoperative morbidity such as intensive care unit length of stay and number of complications after cardiac surgery in children. In a recent multi-center study sponsored by the National Institutes of Health, 311 children undergoing cardiac surgery were enrolled. Morbidity data are ...
Khosrow-Khavar Farzad - - 2014
Seismocardiogram (SCG) is the low frequency vibrations signal recorded from the chest using accelerometers. Peaks on dorsoventral and sternal SCG correspond to specific cardiac events. Prior research work has shown the potential of extracting such peaks for various types of monitoring and diagnosis applications. However, annotation of these peaks is ...
Park Juyoung J Department of Computer Science & Engineering, Hanyang University, Ansan 426-791, Republic of - - 2014
The computer-aided interpretation of electrocardiogram (ECG) signals provides a non-invasive and inexpensive technique for analyzing heart activity under various cardiac conditions. Further, the proliferation of smartphones and wireless networks makes it possible to perform continuous Holter monitoring. However, although considerable attention has been paid to automated detection and classification of ...
Raible Florian F Max F. Perutz Laboratories and Research Platform 'Marine Rhythms of Life', University of Vienna, Dr. Bohr-Gasse 9/4, 1030 Vienna, Austria. Electronic address: - - 2014
A quick guide into the new model annelid Platynereis.
Holmes Millicent M School of Psychology, Deakin University, 221 Burwood Highway, Burwood, VIC, 3125, - - 2014
The present study tests several competing, explanatory models-dual pathways, escape from awareness, and objectification theory-for the established link between body dissatisfaction and binge eating. 408 women aged between 18 and 40 years completed a survey designed to assess contributions of proposed mediators (dietary restraint and negative affect from the dual pathway ...
Campodonico Miguel A MA Centre for Biochemical Engineering and Biotechnology, University of Chile, Beauchef 850, Santiago, Chile; Dept. of Bioengineering, University of California San Diego, 9500 Gilman Drive, Mail Code 0412, La Jolla, CA, 92093, - - 2014
The production of 75% of the current drug molecules and 35% of all chemicals could be achieved through bioprocessing (Arundel and Sawaya, 2009). To accelerate the transition from a petroleum-based chemical industry to a sustainable bio-based industry, systems metabolic engineering has emerged to computationally design metabolic pathways for chemical production. ...
Tollefsen T T European Commission, DG Joint Research Centre, Institute for Transuranium Elements, Via E Fermi 2749, Ispra I-21027, Italy - - 2014
In 2006, the Joint Research Centre of the European Commission launched a project to map radon at the European level, as part of a planned European Atlas of Natural Radiation. It started with a map of indoor radon concentrations. As of May 2014, this map includes data from 24 countries, ...
Dakanalis Antonios A Department of Brain and Behavioral Sciences, University of Pavia, P.za Botta 11, 27100, Pavia, Italy. Electronic address: - - 2014
Stice's (1994, 2001) dual pathway model proposed a mediational sequence that links body dissatisfaction to lack of control over eating through dieting and negative affect. van Strien and colleagues (2005) extended the negative affect pathway of the original dual pathway model by adding two additional intervening variables: interoceptive deficits and ...
Li Pu P Northern Region Persistent Organic Pollution Control (NRPOP) Laboratory, Faculty of Engineering and Applied Science, Memorial University of Newfoundland, St. John's, NL, - - 2014
In this paper, a Monte Carlo simulation based two-stage adaptive resonance theory mapping (MC-TSAM) model was developed to classify a given site into distinguished zones representing different levels of offshore Oil Spill Vulnerability Index (OSVI). It consisted of an adaptive resonance theory (ART) module, an ART Mapping module, and a ...
Liu Renzhi R State Key Laboratory of Water Environment Simulation, School of Environment, Beijing Normal University, No. 19, Xinjiekouwai Street, Haidian District, Beijing 100875, China. Electronic address: - - 2014
Land-use suitability analyses are of considerable use in the planning of mega-cities. An Urban Development Land-use Suitability Mapping (UDLSM) approach has been constructed, based on opportunity and constraint criteria. Two Multi-criteria Evaluation (MCE) methods, the Ideal Point Method (IPM) and Ordered Weighted Averaging (OWA), were used to generate the opportunity ...
Goldman Alyssa W AW Concept Systems, Inc., 136 East State Street, Ithaca, NY 14850, USA. Electronic address: - - 2014
Group concept mapping is a mixed-methods approach that helps a group visually represent its ideas on a topic of interest through a series of related maps. The maps and additional graphics are useful for planning, evaluation and theory development. Group concept maps are typically described, interpreted and utilized through points, ...
Peng Xi X Paul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology of Chinese Academy of Sciences, Shenzhen, Guangdong, China; Beijing Center for Mathematics and Information Interdisciplinary Sciences, Beijing, China; Shenzhen Key Laboratory for MRI, Shenzhen, Guangdong, - - 2014
T2 mapping is a powerful noninvasive technique providing quantitative biological information of the inherent tissue properties. However, its clinical usage is limited due to the relative long scanning time. This paper proposed a novel model-based method to address this problem. Typically, we directly estimated the relaxation values from undersampled k-space ...
Du Junli J College of Sciences, Northwest A&F University, Yangling, 712100, P. R. China. - - 2014
The dynamic impact approach (DIA) represents an alternative to overrepresentation analysis (ORA) for functional analysis of time-course experiments or those involving multiple treatments. The DIA can be used to estimate the biological impact of the differentially expressed genes (DEGs) associated with particular biological functions, for example, as represented by the ...
Zhao Jinying J Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, - - 2014
Although pathway analysis methods have been developed and successfully applied to association studies of common variants, the statistical methods for pathway-based association analysis of rare variants have not been well developed. Many investigators observed highly inflated false-positive rates and low power in pathway-based tests of association of rare variants. The ...
Zheng Yu Y 1 Department of Mathematics, National University of Singapore , Singapore - - 2014
Abstract In the tree reconciliation approach for species tree inference, a tree that has the minimum reconciliation score for given gene trees is taken as an estimate of the species tree. The scoring models used in existing tree reconciliation methods include the duplication, mutation, and deep coalescence costs. Since existing ...
Cox B B Radiology, Institute for Medical Science and Technology, University of Dundee, Dundee, - - 2014
The benefits of learning on simulator have long been established across different areas of practice including medical industry. In particular recent technological advances have produced either flow models or simulators on which practitioners can learn new techniques evaluate new devices or improve their skills outside of direct patient care. None ...
Duquette Philippe M PM McGill University; Department of Anatomy and Cell Biology; Montreal, QC - - 2014
In the last decade, several mouse models for RhoA, Rac1, and Cdc42 have emerged and have contributed a great deal to understanding the precise functions of Rho GTPases at early stages of development. This review summarizes our current knowledge of various mouse models of tissue-specific ablation of Cdc42, Rac1, and ...
Schwartz-Chassidim Hadas H Department of Industrial Engineering and Management, Ben-Gurion University, of the Negev, P.O. Box 653, Beer-Sheva 84105, Israel. Electronic address: - - 2014
Maps should be designed so that users can comprehend and use the information. Display decisions, such as choosing the scale at which an area is shown, depend on properties of the displayed information such as the perceived density (PD) of the information. Taking a psychophysical approach we suggest that the ...
Cao Mengfei M Department of Computer Science, Tufts University, Medford, MA 02155, USA and Department of Computer Science, University of Minnesota, Minneapolis, MN 55455, - - 2014
It has long been hypothesized that incorporating models of network noise as well as edge directions and known pathway information into the representation of protein-protein interaction (PPI) networks might improve their utility for functional inference. However, a simple way to do this has not been obvious. We find that diffusion ...
Ki Seo Jin SJ Department of Civil and Environmental Engineering and Water Resources Research Center, University of Hawaii at Manoa, Honolulu, HI 96822, - - 2014
Determining optimal locations for best management practices (BMPs), including their field considerations and limitations, plays an important role for effective stormwater management. However, these issues have been often overlooked in modeling studies that focused on downstream water quality benefits. This study illustrates the methodology of locating infiltration trenches at suitable ...
Alcaine Alejandro - - 2014
Electroanatomical mapping (EAM) systems are commonly used in clinical practice for guiding catheter ablation treatments of common arrhythmias. In focal tachycardias, the ablation target is defined by locating the earliest activation area determined by the joint analysis of electrogram (EGM) signals at different sites. However, this is currently a manual ...
Zhao Feng - - 2014
Parallel excitation requires fast and accurate B1 map estimation. Bloch-Siegert (BS) B1 mapping is very fast and accurate over a large dynamic range. When applied to multi-coil systems, however, this phase-based method may produce low SNR estimates in low magnitude regions due to localized excitation patterns of parallel excitation systems. ...
Crott Ralph R 1IRSS, Université Catholique de Louvain, Clos Chapelle aux Champs 30 bte 30.15, 1200, Brussels, - - 2014
Aim: Over the last years several mapping or cross-walking algorithms for deriving utilities from QLQ-C30 scores have been published. However their external predictive accuracy has not yet been systematically compared. Methods: We tested the external validity of previously published mapping algorithms to transform the European Organization for Research and Treatment ...
Niemeyer David J DJ Carolinas Medical Center, Charlotte, NC, - - 2014
Introduction. Local ablative therapies, including microwave ablation (MWA), are common treatment modalities for in situ tumor destruction. Currently, 2.45-GHz ablation systems are gaining prominence because of the shorter application times required. The aims of this study were to determine optimal power and time to ablation volume (AbV) ratios for a ...
Hadjicharalambous Myrianthi M Department of Biomedical Engineering, King's College London, St Thomas' Hospital, London SE1 7EH, - - 2014
The Lagrange Multiplier (LM) and penalty methods are commonly used to enforce incompressibility and compressibility in models of cardiac mechanics. In this paper we show how both formulations may be equivalently thought of as a weakly penalized system derived from the statically condensed Perturbed Lagrangian formulation, which may be directly ...
Isachenko Artem A MSU, White Sea Biological Station, Russian Federation. Electronic address: - - 2014
During 2009-2012 stocks of the bivalve Arctica islandica (Linnaeus, 1767) (Ocean quahog) in Kandalaksha Bay (the White Sea) has been assessed using a side-scan sonar, grab sampling and underwater photo imaging. Structurally uniform localities were highlighted on the basis of side-scan signal. Each type of a signal reflects combination of ...
Spinczyk Dominik D Faculty of Biomedical Engineering, Silesian University of Technology, Zabrze, - - 2014
Nowadays the best treatment of the primary and secondary hepatic tumor is surgical resection, but only 5-15% of all patient with hepatocellular carcinoma and 20-25% of all patients with liver metastases are indicated for resection. In these cases some kind of ablation and other technique could be used. To present ...
Bueno Justin J Department of Chemistry, University at Albany, SUNY, 1400 Washington Avenue, Albany, NY, 12222, - - 2014
A novel approach utilizing automated Raman microspectroscopic mapping for gunshot residue (GSR) detection was investigated. A well-established technique for GSR recovery (tape lifting) was utilized for GSR particle collection. Uncontaminated samples of the substrate (tape), organic GSR (OGSR), and inorganic GSR (IGSR) particles were characterized to generate three respective Raman ...
Parker Christopher J CJ a Loughborough Design School , Loughborough University , Loughborough , - - 2014
This paper investigates the influence of presenting volunteered and professionally created geographic information to 101 wheelchair users through an interactive website that included information collected by wheelchair-using volunteers. The aim of this experiment was to understand the influence that (1) knowing a map-based website contains volunteered information and (2) actually ...
Karau Eva C EC USDA Forest Service, Rocky Mountain Research Station, Missoula Fire Sciences Laboratory, 5775 Hwy 10 W, Missoula, MT, 59808, USA, - - 2014
Both satellite imagery and spatial fire effects models are valuable tools for generating burn severity maps that are useful to fire scientists and resource managers. The purpose of this study was to test a new mapping approach that integrates imagery and modeling to create more accurate burn severity maps. We ...
Zhao Bo - - 2014
MR parameter mapping (e.g., T1 mapping, T2 mapping, T 2 mapping) is a valuable tool for tissue characterization. However, its practical utility has been limited due to long data acquisition times. This paper addresses this problem with a new model-based parameter mapping method. The proposed method utilizes a formulation that ...
Ben-Hamo Rotem R The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan 5290002, - - 2014
At the core of transcriptome analyses of cancer is a challenge to detect molecular differences affiliated with disease phenotypes. This approach has led to remarkable progress in identifying molecular signatures and in stratifying patients into clinical groups. Yet, despite this progress, many of the identified signatures are not robust enough ...
Kladwang Wipapat W Department of Biochemistry, Stanford University , Stanford, California 94305, United - - 2014
Chemical mapping experiments offer powerful information about RNA structure but currently involve ad hoc assumptions in data processing. We show that simple dilutions, referencing standards (GAGUA hairpins), and HiTRACE/MAPseeker analysis allow rigorous overmodification correction, background subtraction, and normalization for electrophoretic data and a ligation bias correction needed for accurate deep ...
Martini Paolo - - 2014
Time-course gene expression experiments are useful tools for exploring biological processes. In this type of experiments, gene expression changes are monitored along time. Unfortunately, replication of time series is still costly and usually long time course do not have replicates. Many approaches have been proposed to deal with this data ...
Liu Liping L Department of Ultrasound, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. - - 2014
The aim of the present study was to evaluate the safety and efficiency of an intravenously delivered nano-hydroxyapatite (Nano-HA) solution into a rabbit model (Oryctolagus cuniculus) to determine the potential enhancement of high-intensity focused ultrasound (HIFU) for the ablation of hepatocellular carcinoma (HCC) in liver tissue. The present study clearly ...
Reading Anna S AS a Maddie's Shelter Medicine Program, Department of Population Medicine and Diagnostic Sciences , College of Veterinary Medicine, Cornell - - 2014
A retrospective study using a geographic information system (GIS) was conducted to capture, map, and analyze intake data of caregiver (owner)-surrendered kittens (aged 0-6 months) to the Society for the Prevention of Cruelty to Animals (SPCA) of Tompkins County, NY, from 2009 to 2011. Addresses of caregiver-surrendered kittens during the ...
Blauer Joshua J E JJ CARMA Center, University of Utah, Salt Lake City, Utah; Department of Bioengineering, University of Utah, Salt Lake City, - - 2014
Voltage mapping is an important tool for characterizing proarrhythmic electrophysiological substrate, yet it is subject to geometric factors that influence bipolar amplitudes and thus compromise performance. The aim of this study was to characterize the impact of catheter orientation on the ability of bipolar amplitudes to accurately discriminate between healthy ...
Huang Chuan C Center for Advanced Medical Imaging Sciences, Division of Nuclear Medicine and Molecular Imaging, Department of Imaging, Massachusetts General Hospital, Boston, MA, USA; Department of Radiology, Harvard Medical School, Boston, MA, USA. Electronic address: - - 2014
Indirect echoes (such as stimulated echoes) are a source of signal contamination in multi-echo spin-echo T2 quantification and can lead to T2 overestimation if a conventional exponential T2 decay model is assumed. Recently, nonlinear least square fitting of a slice-resolved extended phase graph (SEPG) signal model has been shown to ...
Zhao Bin - - 2014
Exposure to airborne semivolatile organic compounds (SVOCs) in indoor and outdoor environments of humans may lead to adverse health risks. Thus, we established a model to evaluate exposure to airborne SVOCs. In this model, SVOCs phase-specific concentrations were estimated by a kinetic partition model accounting for particle dynamics. The exposure ...
Kireeva Natalia V NV Laboratory of New Physical-Chemical Problems, Frumkin Institute of Physical, Chemistry & Electrochemistry, Russian Academy of Sciences, Leninsky pr-t 31, 119071 Moscow (Russia); Department of Molecular Physics, Moscow Institute of Physics & Technology, Institutsky per. 9, 141700, Dolgoprudny (Russia). - - 2014
Over the years, a number of dimensionality reduction techniques have been proposed and used in chemoinformatics to perform nonlinear mappings. In this study, four representatives of nonlinear dimensionality reduction methods related to two different families were analyzed: distance-based approaches (Isomap and Diffusion Maps) and topology-based approaches (Generative Topographic Mapping (GTM) ...
Huang Anhui A Department of Electrical and Computer Engineering, University of Miami, Coral Gables, Florida, United States of - - 2014
Pathway-based genome-wide association studies (GWAS) can exploit collective effects of causal variants in a pathway to increase power of detection. However, current methods for pathway-based GWAS do not consider epistatic effects of genetic variants, although interactions between genetic variants may play an important role in influencing complex traits. In this ...
Kerpedjiev Peter - - 2014
Modern DNA sequencing methods produce vast amounts of data that often requires mapping to a reference genome. Most existing programs use the number of mismatches between the read and the genome as a measure of quality. This approach is without a statistical foundation and can for some data types result ...
Ugarte Maria Dolores MD 1Department of Statistics and O. R., Public University of Navarre, - - 2014
Spatio-temporal disease mapping comprises a wide range of models used to describe the distribution of a disease in space and its evolution in time. These models have been commonly formulated within a hierarchical Bayesian framework with two main approaches: an empirical Bayes (EB) and a fully Bayes (FB) approach. The ...
Wang Changqing C School of Automation Engineering, University of Electronic Science and Technology of China, Chengdu, China; School of Biomedical Engineering, Southern Medical University, Guangzhou, - - 2014
Fitting the measured decay signal to the first moment in the presence of noncentral chi noise (M(1) NCM) can correctly address the effect of noise on the effective transverse relaxation rate (R2*) relaxometry of iron loaded liver. However, this method requires intensive computation, which restricts its application to R2* mapping. ...
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