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Gibbons Melissa M MM Department of Mechanical and Aerospace Engineering, UCLA, 420 Westwood Plaza, Los Angeles, CA, 90095, - - 2015
Viral capsids undergo significant mechanical deformations during their assembly, maturation, and infective life-span. In order to characterize the mechanics of viral capsids, their response to applied external forces is analyzed in several experimental studies using, for instance, Atomic Force Microscope (AFM) indentation experiments. In recent years, a broader approach to ...
Bedell Victoria M VM Department of Biochemistry and Molecular Biology, Mayo Clinic, Guggenheim 1321A, 200 1st Street South, Rochester, MN, 55905, - - 2015
Over the last few years, the technology to create targeted knockout and knockin zebrafish animals has exploded. We have gained the ability to create targeted knockouts through the use of zinc finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs) and clustered regularly interspaced short palindromic repeats/CRISPR associated system (CRISPR/Cas). Furthermore, ...
Griffith Richard R Swansea - - 2014
Although healthcare assistants (HCAs) are not registered practitioners, they are still accountable to a range of people who regulate their conduct.
Chesi Cristiano C IUSS - Institute for Advanced Study of Pavia, Piazza Vittoria 15, I-27100, Pavia, Italy, - - 2014
Minimalism in grammatical theorizing (Chomsky in The minimalist program. MIT Press, Cambridge, 1995) led to simpler linguistic devices and a better focalization of the core properties of the structure building engine: a lexicon and a free (recursive) phrase formation operation, dubbed Merge, are the basic components that serve in building ...
Li Siran S Lewis-Sigler Institute for integrative Genomics, Princeton University, Princeton, NJ 08544, USA. - - 2014
The nematode Caenorhabditis elegans (C. elegans) is an excellent model to study reproductive aging because of its short life span, its cessation of reproduction in mid-adulthood, and the strong conservation of pathways that regulate longevity. During its lifetime, a wild-type C. elegans hermaphrodite usually lays about 200-300 self-fertilized hatchable eggs, ...
Summers Jennifer A JA King's Technology Evaluation Centre, London, UK, - - 2014
The geko™ device is a single-use, battery-powered, neuromuscular electrostimulation device that aims to reduce the risk of venous thromboembolism (VTE). The National Institute for Health and Care Excellence (NICE) selected the geko™ device for evaluation, and invited the manufacturer, Firstkind Ltd, to submit clinical and economic evidence. King's Technology Evaluation ...
Wang Xiaopu X Department of Chemical Engineering, School of Engineering and Applied Science, University of Virginia, Charlottesville, VA, - - 2014
Chemotaxis has been shown to be beneficial for the migration of soil-inhabiting bacteria towards industrial chemical pollutants, which they degrade. Many studies have demonstrated the importance of this microbial property under various circumstances; however, few quantitative analyses have been undertaken to measure the two essential parameters that characterize the chemotaxis ...
Pibouleau Leslie L Univ Paris Diderot;Sorbonne Paris Cité;INSERM UMR 717;Hop Saint-Louis,Service de Biostatistique et information - - 2014
Rationale: Bayesian methods provide an interesting approach to assessing an implantable medical device (IMD) that has evolved through successive versions because they allow for explicit incorporation of prior knowledge into the analysis. However, the literature is sparse on the feasibility and reliability of elicitation in cases where expert beliefs are ...
Song Yeongtak Y 1 School of Electrical Engineering, University of Ulsan , Ulsan, - - 2014
Abstract Background: Although many smartphone application (app) programs provide education and guidance for basic life support, they do not commonly provide feedback on the chest compression depth (CCD) and rate. The validation of its accuracy has not been reported to date. This study was a feasibility assessment of use of ...
Carbonell-Ballestero Max M ICREA-Complex Systems Laboratory, Universitat Pompeu Fabra, 08003 Barcelona, Spain Institut de Biologia Evolutiva, CSIC-UPF, Psg. de la Barceloneta 37, 08003 Barcelona, - - 2014
Within the field of synthetic biology, a rational design of genetic parts should include a causal understanding of their input-output responses-the so-called transfer function-and how to tune them. However, a commonly adopted strategy is to fit data to Hill-shaped curves without considering the underlying molecular mechanisms. Here we provide a ...
Holmes Martin S MS 1 Trinity Centre for Bioengineering, Trinity College Dublin , Ireland - - 2014
Abstract Background: Dry powder inhaler (DPI) users frequently exhale into their inhaler mouthpiece before the inhalation step. This error in technique compromises the integrity of the drug and results in poor bronchodilation. This study investigated the effect of four exhalation factors (exhalation flow rate, distance from mouth to inhaler, exhalation ...
Dargar Saurabh - - 2014
We have developed an instrumented endoscope grip handle equipped with a 6-axis load cell and measured forces and torques during a simulated transgastric NOTES appendectomy procedure performed in an EASIE-R© ex vivo simulator. The data were collected from 10 participating surgeons of varying degrees of expertise which was analyzed to ...
Selby Edward A EA Rutgers, The State University of New - - 2014
Influenced by chaos theory, the Emotional Cascade Model proposes that rumination and negative emotion may promote each other in a self-amplifying cycle that increases over time. Accordingly, exponential-compounding effects may better describe the relationship between rumination and negative emotion when they occur in impulsive persons, and predict impulsive behavior. Participants ...
Weaver Abigail A AA Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, 46556, USA, - - 2014
Paper-based devices serve to address many analytical questions both inside and outside of the laboratory setting. For the first time, yeast is used to construct a whole-cell, paper-based biosensor device. This biologically based paper analytical device (BioPAD) is sensitive to antibiotics in the tetracycline family, and it could potentially address ...
Ferros Isabel I *Department of Stomatology, Facultad de Medicina y Odontología, Universidad de Santiago de - - 2014
Summary INTRODUCTION: It is widely accepted that there is a relationship between the cranial base and the development of the nasomaxillary complex (NMC). The objective of the present study was to investigate the morphological relationship between these two anatomical units in skulls that have intentionally been subjected to one of ...
Fini Natalie A NA Department of Physiotherapy, La Trobe University , Melbourne , Australia - - 2014
Abstract Purpose: To describe how physical activity is monitored following stroke; to summarise methods and devices used across the stroke pathway and document their psychometric properties. Methods: Searches of five databases identified studies that included stroke survivors whose physical activity was quantitatively measured. Two reviewers independently determined inclusion. A descriptive ...
Cate David M - - 2014
Paper is a centuries old substrate for carrying out chemical measurements. The application of paper as a platform for microfluidics, however, was only introduced to the scientific community less than ten years ago and has become a major new field of research. Microfluidic paper-based analytical devices are attractive as sensors ...
Shi Yingzhong - - 2014
Recently, a time-adaptive support vector machine (TA-SVM) is proposed for handling nonstationary datasets. While attractive performance has been reported and the new classifier is distinctive in simultaneously solving several SVM subclassifiers locally and globally by using an elegant SVM formulation in an alternative kernel space, the coupling of subclassifiers brings ...
Eidels Ami A School of Psychology, University of Newcastle, Callaghan, New South Wales, 2308, Australia, - - 2014
This investigation brings together a response-time system identification methodology (e.g., Townsend & Wenger Psychonomic Bulletin & Review 11, 391-418, 2004a) and an accuracy methodology, intended to assess models of integration across stimulus dimensions (features, modalities, etc.) that were proposed by Shaw and colleagues (e.g., Mulligan & Shaw Perception & Psychophysics ...
Davidsohn Noah - - 2014
A long-standing goal of synthetic biology is to rapidly engineer new regulatory circuits from simpler devices. As circuit complexity grows, it becomes increasingly important to guide design with quantitative models, but previous efforts have been hindered by lack of predictive accuracy. To address this, we developed Empirical Quantitative Incremental Prediction ...
Beqiri Arian A Division of Imaging Sciences and Biomedical Engineering, King's College - - 2014
The use of electromagnetic (EM) modeling is critical for specific absorption rate (SAR) characterization in parallel transmission MRI. Radiofrequency arrays that include decoupling networks can be difficult to characterize accurately in simulation. A practical method of simplifying modeling is to exclude the decoupling networks and model each transmit element in ...
Fraiwan Arwa A Bioelectronics & Microsystems Laboratory, Department of Electrical & Computer Engineering, State University of New York-Binghamton, Binghamton, NY 13902, USA. - - 2014
Paper-based devices have recently emerged as simple and low-cost paradigms for fluid manipulation and analytical/clinical testing. However, there are significant challenges in developing paper-based devices at the system level, which contain integrated paper-based power sources. Here, we report a microfabricated paper-based bacteria-powered battery that is capable of generating power from ...
Li Ruo-Zhou - - 2014
Paper-based capacitive touch pads can be fabricated utilizing high concentration silver nanowire inks needle-printed directly onto paper substrates through a 2D programmable platform. Post deposition, silver nanowire tracks can be photonically sintered using a camera flash to reduce sheet resistance similar to thermal sintering approaches. Touch pad sensors on a ...
Sagha Hesam - - 2014
One of the problems of non-invasive Brain- Computer Interface (BCI) applications is the occurrence of anomalous (unexpected) signals that might degrade BCI performance. This situation might slip the operator's attention since raw signals are not usually continuously visualized and monitored during BCI-actuated device operation. Anomalous data can for instance be ...
Yang Shiming S Data Analyst, University of Maryland School of Medicine, Baltimore, Maryland 21201, - - 2014
Massive clinical digital data routinely collected by high throughput biomedical devices provide opportunities and challenges for optimal use. This article discusses how such data are used in learning prediction models at level 1 trauma centres to support decision making in trauma patients.
Skolarus Lesli E LE Stroke Program, Department of Neurology and - - 2014
To explore use of assistive devices and personal assistance and unmet need for assistance among older stroke survivors and identify potentially modifiable factors to optimize self-care and mobility activities in this population. Using the 2011 National Health and Aging Trends Study, we compared demographic characteristics, accommodation-enabling factors and need-related factors ...
Shepherd Micah R MR Applied Research Laboratory, The Pennsylvania State University, University Park, Pennsylvania 16802 mrs30@psu.edu, sah19@psu.edu, - - 2014
A finite element model of a bare top plate with braces and a bridge plate was created using orthotropic material properties. The natural variation of the wood properties including dependence on moisture content was also determined. The simulated modes were then compared to experimentally obtained modes from top plate prototypes. ...
Ma Xin - - 2014
Falls are one of the major causes leading to injury of elderly people. Using wearable devices for fall detection has a high cost and may cause inconvenience to the daily lives of the elderly. In this paper, we present an automated fall detection approach that requires only a low-cost depth ...
Magalhaes Fabricio Anicio de FA a Department of Electrical, Electronic, and Information Engineering "Guglielmo Marconi" , University of Bologna , Bologna , - - 2014
Abstract The use of contemporary technology is widely recognised as a key tool for enhancing competitive performance in swimming. Video analysis is traditionally used by coaches to acquire reliable biomechanical data about swimming performance; however, this approach requires a huge computational effort, thus introducing a delay in providing quantitative information. ...
Freeman Chris - - 2014
Abstract Functional electrical stimulation (FES) has been shown to be an effective approach to upper-limb stroke rehabilitation, where it is used to assist arm and shoulder motion. Model-based FES controllers have recently confirmed significant potential to improve accuracy of functional reaching tasks, but they typically require a reference trajectory to ...
Arbizu Carlos C USDA-Agricultural Research Service, Vegetable Crops Research Unit, Department of Horticulture, University of Wisconsin-Madison, 1575 Linden Dr., Madison, Wisconsin 53706-1590 - - 2014
• Molecular phylogenetics of genome-scale data sets (phylogenomics) often produces phylogenetic trees with unprecedented resolution. A companion phylogenomics analysis of Daucus using 94 conserved nuclear orthologs supported many of the traditional species but showed unexpected results that require morphological analyses to help interpret them in a practical taxonomic context.• We ...
Yeari Menahem M a School of Education , Bar Ilan University , Ramat-Gan , - - 2014
The present research adopted a computational approach to explore the extent to which the semantic content of texts constrains the activation of knowledge-based inferences. Specifically, we examined whether textual semantic constraints (TSC) can explain (1) the activation of predictive inferences, (2) the activation of bridging inferences and (3) the higher ...
Kauer Michaela M a Institute of Ergonomics & Human Factors, Technische Universität Darmstadt , Otto-Berndt-Straße 2, 64287 Darmstadt , - - 2014
Today, new driving paradigms are being introduced that aim to reduce the number of standalone driver assistance systems by combining these into one overarching system. This is done to reduce the demands on drivers but often leads to a higher degree of automation. Feasibility and driver behaviour are often the ...
Cai B B Department of Orthopedics, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai, - - 2014
Our goal was to analyze the anatomical parameters of the lumbar spine spinous process for an interspinous stabilization device designed for the Chinese population and to offer an anatomical basis for its clinical application. The posterior lumbar spines (T12-S1) of 52 adult cadavers were used for measuring the following: distance ...
Eliseyev Andrey A Clinatec/LETI/CEA, Grenoble, - - 2014
Objective. The key criterion for reliability of brain-computer interface (BCI) devices is their stability and robustness in natural environments in the presence of spurious signals and artifacts. Approach. To improve stability and robustness, a generalized additive model (GAM) is proposed for BCI decoder identification. Together with partial least squares (PLS), ...
Iakovou Georgios G School of Computing Sciences, University of East Anglia, Norwich, Norfolk NR4 7TJ, UK. s.laycock@uea.ac.uk - - 2014
Intermolecular binding underlies every metabolic and regulatory processes of the cell, and the therapeutic and pharmacological properties of drugs. Molecular docking systems model and simulate these interactions in silico and allow us to study the binding process. Haptic-based docking provides an immersive virtual docking environment where the user can interact ...
Giustini Marco M Department of Environment and Primary Prevention, Italian National Institute of Health, Rome, Italy, Scientific responsible of the ST.E.P. project, Department of Environment and Primary Prevention, Italian National Institute of Health, Rome, Italy, Informatics Service, Italian National Institute of Health, Rome, Italy and Santa Lucia Foundation, Post Coma Unit, Rome, Italy - - 2014
The international scientific literature reports no data on the prevalence and effectiveness of back protector devices (BPD). In Italy, no data have been collected on BPD because their use is not mandatory. To fill this gap, the National Institute of Health implemented a cross-sectional study in collaboration with the National ...
Buganè Francesca - - 2014
Kinematics measures from inertial sensors have a value in the clinical assessment of pathological gait, to track quantitatively the outcome of interventions and rehabilitation programs. To become a standard tool for clinicians, it is necessary to evaluate their capability to provide reliable and comprehensible information, possibly by comparing this with ...
Palamara Simone S Modellistica e Calcolo Scientifico (MOX), Dipartimento di Matematica, Politecnico di Milano, Milan, - - 2014
To properly describe the electrical activity of the left ventricle it is necessary to model the Purkinje fibers, responsible for the fast and coordinate ventricular activation, and their interaction with the muscular propagation. The aim of this work is to propose a methodology for the generation of a patient-specific Purkinje ...
Wang Pei-Ling PL National Chi Nan University, Nantou County, Taiwan - - 2014
The Taiwan Intimate Partner Violence Danger Assessment (TIPVDA) is an IPV risk assessment instrument developed to assist front-line professionals with assessing victim's likelihood of experiencing lethal danger, and is also used to identify intervention strategies. The validation of TIPVDA with an independent sample of 543 female IPV victims in a ...
Ijspeert Auke J AJ Biorobotics Laboratory, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne, - - 2014
The graceful and agile movements of animals are difficult to analyze and emulate because locomotion is the result of a complex interplay of many components: the central and peripheral nervous systems, the musculoskeletal system, and the environment. The goals of biorobotics are to take inspiration from biological principles to design ...
Schonhorn Jeremy E JE Diagnostics For All, 840 Memorial Drive, Cambridge, MA 02139, USA. jschonhorn@dfa.org - - 2014
Diagnostic assays can provide valuable information about the health status of a patient, which include detection of biomarkers that indicate the presence of an infection, the progression or regression of a disease, and the efficacy of a course of treatment. Critical healthcare decisions must often be made at the point-of-care, ...
Coons Stephen Joel SJ Critical Path Institute, Tucson, AZ, USA, - - 2014
Patient-reported outcomes (PROs) are an important means of evaluating the treatment benefit of new medical products. It is recognized that PRO measures should be used when assessing concepts best known by the patient or best measured from the patient's perspective. As a result, there is growing emphasis on well defined ...
Xu Yafan - - 2014
Cost aggregation is the most important step in a local stereo algorithm. In this work, a novel local stereo-matching algorithm with a cost-aggregation method based on adaptive shape support window (ASSW) is proposed. First, we compute the initial cost volume, which uses both absolute intensity difference and gradient similarity to ...
Cancilla John C - - 2014
A wide variety of olive oil samples from different origins and olive types have been chemically analyzed, as well as evaluated by trained sensory panelists. Six chemical parameters have been obtained for each sample (free fatty acids, peroxide value, two UV absorption parameters (K232 and K268), 1,2-diacylglycerol content, and pyropheophytins), ...
Giese Heiko H Molecular Bioinformatics Group, Institute of Computer Science, Faculty of Computer Science and Mathematics, Cluster of Excellence Frankfurt "Macromolecular Complexes", Goethe-University, Robert-Mayer-Str. 11-15, 60325 Frankfurt am Main, - - 2014
We introduce nova, a software for the analysis of complexome profiling data. nova supports the investigation of the composition of complexes, cluster analysis of the experimental data, visual inspection and comparison of experiments, and many other features. Availability and implementation: nova is licensed under the Artistic License 2.0. It is ...
Bakhsh Hadeel H aDepartment of Physical Medicine and Rehabilitation, Tor Vergata University, Rome bUnit of Occupational Rehabilitation and Ergonomics cUnit of Bioengineering, Salvatore Maugeri Foundation, Scientific Institute of Veruno, Veruno, Italy dSchool of Rehabilitation, Faculty of Medicine, Université de Montréal, Montreal, Quebec, - - 2014
The assessment of patient satisfaction with the orthosis is a key point for clinical practice and research, requiring the availability of questionnaires with robust psychometric properties. The aim of this study was the translation into Arabic and Rasch validation of the Quebec User Evaluation of Satisfaction with assistive Technology (A-QUEST ...
Soguero-Ruiz Cristina - - 2014
The free text in Electronic Health Records (EHRs) conveys a huge amount of clinical information about health state and patient history. Despite a rapidly growing literature on the use of machine learning techniques for extracting this information, little effort has been invested towards feature selection and the features' corresponding medical ...
Kim Sangwook S School of Electronics Engineering, Kyungpook National University, 1370 Sankyuk-Dong, Puk-Gu, Taegu 702-701, Republic of - - 2014
Deep learning methods endeavor to learn features automatically at multiple levels and allow systems to learn complex functions mapping from the input space to the output space for the given data. The ability to learn powerful features automatically is increasingly important as the volume of data and range of applications ...
Hildebrandt Christoph C a BMW Group, Knorrstr. 147 , D-80937 - - 2014
Objective: To develop and verify a driver assistance function, working on the electric power steering of passenger cars, to support the driver on handling critical understeer situations. The main objectives of the so-called understeer-assistance are reinforcing the driver's awareness of the driving conditions and giving support to handle the situation ...
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