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De Oliveira Victor V Department of Management Science and Statistics, The University of Texas at San Antonio, San Antonio, TX 78249, - - 2015
Methodology is proposed for the construction of prediction intervals for integrals of Gaussian random fields over bounded regions (called block averages in the geostatistical literature) based on observations at a finite set of sampling locations. Two bootstrap calibration algorithms are proposed, termed indirect and direct, aimed at improving upon plug-in ...
Samsonov Sergey A - - 2014
Glycosaminoglycans (GAGs) represent a class of anionic periodic linear polysaccharides, which mediate cell communication processes by interactions with their protein targets in the extracellular matrix. Due to their high flexibility, charged nature, periodicity, and polymeric nature GAGs are challenging systems for computational approaches. To deal with the length challenge, coarse-grained ...
Mathern Gary W GW Departments of Neurosurgery and Psychiatry & BioBehavioral Medicine, David Geffen School of Medicine, The Mattel Children's Hospital, University of California, Los Angeles, California, - - 2014
From May to September 2014, Epilepsia conducted an online survey seeking opinions on whether consciousness should be used in describing focal and generalized seizures, and what terms should be applied to describe focal seizures with loss of awareness and amnesia. This study reports the findings of that survey. Two questions ...
Shubov Marianna A MA Department of Mathematics and Statistics , University of New Hampshire , 33 Academic Way, Durham, NH 03824, - - 2014
The paper deals with unstable aeroelastic modes for aircraft wing model in subsonic, incompressible, inviscid air flow. In recent author's papers asymptotic, spectral and stability analysis of the model has been carried out. The model is governed by a system of two coupled integrodifferential equations and a two-parameter family of ...
Peters Richard L RL Forest Ecology & Forest Management group, Wageningen University, P.O. Box 47, 6700AA, Wageningen, The Netherlands; Landscape Dynamics, Swiss Federal Research Institute for Forest, Snow and Landscape Research (WSL), Zürcherstrasse 111, CH-8903, Birmensdorf, - - 2014
Tree-ring analysis is often used to assess long-term trends in tree growth. A variety of growth-trend detection methods (GDMs) exist to disentangle age/size trends in growth from long-term growth changes. However, these detrending methods strongly differ in approach, with possible implications for their output. Here we critically evaluate the consistency, ...
Finkelstein Alexei V - - 2014
This paper presents a simple but general analytical estimate of the characteristic time of crossing a long, high and arbitrary bumpy free energy barrier in the course of a sequential (one-dimensional) chemical, biochemical or physical reaction. This estimate is based on a generalized steady-state approach developed in this paper.
Lloyd Rhodri S RS 1Youth Physical Development Unit, School of Sport, Cardiff Metropolitan University, UK 2The College of New Jersey, Department of Health and Exercise Science, Ewing, New Jersey, USA 3Department of Kinesiology, Temple University, Philadelphia, Pennsylvania, USA 4School of Sport and Exercise, University of Gloucestershire, UK 5Children's Health and Exercise Research Centre, Exeter University, UK 6Division of Sports Medicine, Department of Family Medicine, Sports Health and Performance Institute, Ohio State University, Ohio, USA 7Rocky Mountain University of Health Professions, Provo, Utah, USA 8Department of Orthopaedics, Division of Sports Medicine, Boston Children's Hospital, Boston, Massachusetts, USA 9Harvard Medical School, Boston, Massachusetts, USA 10The Micheli Center for Sports Injury Prevention, Boston, MA 11Department of Trauma and Orthopaedics, University of Wales, Cardiff, UK 12Department of Kinesiology, University of Rhode Island, USA 13Sport Performance Research Institute New Zealand, AUT University, NZ 14School of Exercise, Health and Biomedical Sciences, Edith Cowan University, Western Australia, AUS 15Division of Sports Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA 16Department of Pediatrics and Orthopaedic Surgery, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA 17Sports Health and Performance Institute, Ohio State University, Ohio, - - 2014
The first installment of this two-part commentary reviewed existing models of long-term athletic development. However, irrespective of the model that is adopted by practitioners, existing structures within competitive youth sports in addition to the prevalence of physical inactivity in a growing number of modern day youth, may serve as potential ...
Klompmaker Jochem O JO Institute for Risk Assessment Sciences (IRAS), Division of Environmental Epidemiology, Utrecht University, Utrecht, The - - 2014
Recently, short-term monitoring campaigns have been carried out to investigate the spatial variation of air pollutants within cities. Typically, such campaigns are based on short-term measurements at relatively large numbers of locations. It is largely unknown how well these studies capture the spatial variation of long term average concentrations. The ...
Kovach Ryan P RP U.S. Geological Survey, Northern Rocky Mountain Science Center, Glacier Field Station, West Glacier, MT, 59936; Biology and Marine Biology Program, University of Alaska Southeast, Juneau, AK, - - 2014
Pacific salmon migration timing can drive population productivity, ecosystem dynamics, and human harvest. Nevertheless, little is known about long-term variation in salmon migration timing for multiple species across broad regions. We used long-term data for five Pacific salmon species throughout rapidly warming Southeast Alaska to describe long-term changes in salmon ...
Abrams Marc D MD Department of Ecosystem Science and Management, Penn State University, 307 Forest Resources Building, University Park, PA, 16802, - - 2014
The Pederson et al. (2014) letter deals ostensibly with their opinion that we (Nowacki & Abrams 2014) failed to consider the lessening of drought after the 1930s as a major driver of post-European forest dynamics in the eastern U.S. We are befuddled by this because our paper includes long-term precipitation data ...
Spiwok Vojtěch V Department of Biochemistry and Microbiology, Institute of Chemical Technology, Prague, Technická 3, Prague 6, 166 28, Czech Republic. Electronic address: - - 2014
Biomolecular simulations are routinely used in biochemistry and molecular biology research; however, they often fail to match expectations of their impact on pharmaceutical and biotech industry. This is caused by the fact that a vast amount of computer time is required to simulate short episodes from the life of biomolecules. ...
Korhonen Marko M Department of Economics, University of Oulu, P.O. Box 4600, 90014, Oulu, Finland, - - 2014
We investigate the determinants of suicide in Finland using annual data for consumption and suicides from 1860 to 2010. Instead of using some ad hoc measures of cyclical movements of the economy, we build our analysis on a more solid economic theory. A key feature is the habit persistence in ...
Ardeshiri Anam A Department of Transportation and Urban Infrastructure Studies, Morgan State University, 1700 E. Cold Spring Lane, Baltimore, MD 21251, USA. Electronic address: - - 2014
Violating speed limits is a major cause of motor vehicle crashes. Various techniques have been adopted to ensure that posted speed limits are obeyed by drivers. This study investigates the effect of dynamic speed display signs (DSDSs) on drivers' compliance with posted speed limit. An extensive speed data collection upstream ...
Pienkowski Martin - - 2014
Hyperacusis can be extremely debilitating, and at present, there is no cure. In this detailed review of the field, we consolidate present knowledge in the hope of facilitating future research. We review and reference the literature on hyperacusis and related areas. This is the 2nd of a 2-part review. Hyperacusis ...
Barth Hilary H Department of Psychology, Wesleyan University, - - 2014
A large collection of estimation phenomena (e.g. biases arising when adults or children estimate remembered locations of objects in bounded spaces; Huttenlocher, Newcombe & Sandberg, 1994) are commonly explained in terms of complex Bayesian models. We provide evidence that some of these phenomena may be modeled instead by a simpler ...
Bieler Noah S NS Laboratory of Physical Chemistry, ETH Zürich, CH-8093 Zürich, - - 2014
In a recent article [Bieler et al., J. Chem. Theory Comput. 10, 3006-3022 (2014)], we introduced a combination of the λ-dynamics (λD) approach for calculating alchemical free-energy differences and of the local-elevation umbrella-sampling (LEUS) memory-based biasing method to enhance the sampling along the alchemical coordinate. The combined scheme, referred to ...
Ruhí Albert A Global Institute of Sustainability, Arizona State University, Tempe, AZ, 85287, - - 2014
Changing climate extremes and invasion by non-native species are two of the most prominent threats to native faunas. Predicting the relationships between global change and native faunas requires a quantitative toolkit that effectively links the timing and magnitude of extreme events to variation in species abundances. Here, we examine how ...
Schubert K Oliver KO Discipline of Psychiatry, School of Medicine, University of Adelaide, - - 2014
Psychotic illnesses such as schizophrenia and other non-affective psychoses are heterogeneous in disease course and functional outcomes. We review evidence from investigations in clinical psychiatry, neuroimaging, neurocognition, and blood biomarker research suggesting that distinct bio-psycho-social patterns exist at the onset and during the early phase of a First Episode Psychosis ...
Susko Edward E Department of Mathematics and Statistics, Dalhousie University, Halifax, Nova Scotia - - 2014
Previous work on the star-tree paradox has shown that Bayesian methods suffer from a long branch attraction bias. That work is extended to settings involving more taxa and partially resolved trees. The long branch attraction bias is confirmed to arise more broadly and an additional source of bias is found. ...
Liu Liang L Department of Statistics, University of Georgia, Athens, GA Institute of Bioinformatics, University of Georgia, Athens, GA - - 2014
It is well known that species with elevated substitution rates can give rise to disproportionately long branches in the species tree. This combination of long and short branches can contribute to long-branch artifacts (LBA). Despite efforts to remedy LBA via increased taxon sampling and methodological improvements in gene tree estimation, ...
Dao A A International Center for Excellence in Research (ICER), University of Sciences, Techniques and Technologies, BP 1805, Bamako, - - 2014
During the long Sahelian dry season, mosquito vectors of malaria are expected to perish when no larval sites are available; yet, days after the first rains, mosquitoes reappear in large numbers. How these vectors persist over the 3-6-month long dry season has not been resolved, despite extensive research for over ...
Driscoll David F DF Stable Solutions LLC, Easton, MA, and Faculty of Medicine, University of Massachusetts (UMASS) Medical School, Worcester, MA, - - 2015
In the 20th century, the potential clinical application of lipid emulsions (LEs) for intravenous application was extensively studied, and this goal was eventually accomplished. The first safe LE for clinical use that was based on soybean oil was introduced in 1961. In the 1980s, LEs based on mixtures of soybean ...
Troncoso Americo Boza AB Chemical Engineering and Applied Chemistry, University of Toronto, 200 College Street, Room 131, Toronto, Ontario M5S3E5, Canada. - - 2014
This work introduces the first of a two part thermodynamic framework to estimate the solubilization of nonpolar oils in micelles conformed by nonionic surfactants with linear alkyl tails, considering their configuration and the molecular properties of the constituents. This first part introduces a formal approach to account for the lipophilic ...
Haregeweyn Nigussie N Arid Land Research Center, Tottori University, 1390 Hamasaka, Tottori, 680-0001, Japan, - - 2015
Unprecedented land use and land cover (LULC) changes in the Gilgel Tekeze catchment of the upper Nile River basin in Ethiopia may have far-reaching consequences for the long-term sustainability of the natural resources base. This study analyzed the dynamics and hydrologic effects of LULC changes between 1976 and 2003 as ...
Piepho Hans-Peter HP Biostatistics Unit, Institute of Crop Science, University of Hohenheim, Fruwirthstrasse 23, Stuttgart, 70599, - - 2014
Meta-analysis of a set of clinical trials is usually conducted using a linear predictor with additive effects representing treatments and trials. Additivity is a strong assumption. In this paper, we consider models for two or more treatments that involve multiplicative terms for interaction between treatment and trial. Multiplicative models provide ...
Zachar Peter P aDepartment of Psychology, Auburn University Montgomery, Montgomery, Alabama bDepartment of Psychiatry, New York State Psychiatric Institute, Columbia University, New York, New York, - - 2014
To propose options for gradually transitioning to a thoroughgoing dimensional model of personality disorder. The American Psychiatric Association was less willing to implement a dimensional approach to the diagnosis of personality disorder than the leadership of the DSM-5 anticipated. The next opportunity to implement such an approach will be in ...
Becker Johannes J Van Oord Dredging and Marine Contractors B.V., P.O. Box 8574, 3009 AN Rotterdam, The - - 2014
Far field modelling of dredging induced suspended sediment plumes is important while assessing the environmental aspects of dredging. Realistic estimation of source terms, that define the suspended sediment input for far field dredge plume modelling, is key to any assessment. This paper describes a generic method for source term estimation ...
Nakai Kiyohiko K Clinical Research Planning Department, Chugai Pharmaceutical Co., Ltd, 2-1-1, Nihonbashi Muromachi, Chuo-ku, Tokyo, 103-8324, Japan, - - 2014
Ibandronate, a nitrogen-containing bisphosphonate, is a bone resorption inhibitor widely used to prevent and treat osteoporosis. To optimize the design for a long-term clinical study of ibandronate, modeling and simulation (M&S) was performed based on the result of population pharmacodynamic analysis using the data of a short-term clinical study. A ...
Amblard Pierre-Olivier PO GIPSAlab/CNRS UMR 5216, Grenoble, France, - - 2014
Studying the flow of information between different areas of the brain can be performed using the so-called partial directed coherence (PDC). This measure is usually evaluated by first identifying a multivariate autoregressive model and then using Fourier transforms of the impulse responses identified and applying appropriate normalizations. Here, we present ...
Roseman Charles C CC Department of Anthropology, University of Illinois, Urbana, IL 61802, USA. Electronic address: - - 2014
Genetic resemblances among groups are non-randomly distributed in humans. This population structure may influence the correlations between traits and environmental drivers of natural selection thus complicating the interpretation of the fossil record when modern human variation is used as a referential model. In this paper, we examine the effects of ...
Jayasundara Duleepa D Optimisation and Pattern Recognition Research Group, Melbourne School of Engineering, The University of Melbourne, Parkville, VIC 3010, Australia. - - 2014
The combined effect of a high replication rate and the low fidelity of the viral polymerase in most RNA viruses and some DNA viruses results in the formation of a viral quasispecies. Uncovering information about quasispecies populations significantly benefits the study of disease progression, antiviral drug design, vaccine design and ...
Coles Steve L SL Bishop Museum, 1525 Bernice Street Honolulu, HI 96817, USA; Hawai'i Institute of Marine Biology, Kāne'ohe, HI 96744, USA. Electronic address: - - 2014
The coastline of Muscat, Oman, contains some of the most extensive and diverse coral reefs in the northeastern Arabian Peninsula. In the past two decades this region has been impacted by expanding coastal development, the largest cyclone ever recorded in the Arabian Sea, and a large-scale harmful algal bloom which ...
Awad Louis N LN University of Delaware, Newark, DE, - - 2014
Background. Elucidation of the relative importance of commonly targeted biomechanical variables to poststroke long-distance walking function would facilitate optimal intervention design. Objectives. To determine the relative contribution of variables from 3 biomechanical constructs to poststroke long-distance walking function and identify the biomechanical changes underlying posttraining improvements in long-distance walking function. ...
Gomis Melissa Ines MI Department of Applied Environmental Science (ITM), Stockholm University, SE-10691 Stockholm, - - 2014
Long-chain perfluoroalkyl carboxylic acids (PFCAs) and perfluoroalkane sulfonic acids (PFSAs) are persistent, bioaccumulative, and toxic contaminants that are globally present in the environment, wildlife and humans. Phase-out actions and use restrictions to reduce the environmental release of long-chain PFCAs, PFSAs and their precursors have been taken since 2000. In particular, ...
Smith Rob R Department of Computer Science, University of Montana, Missoula, MT 59812 - - 2014
Countless proteomics data processing algorithms have been proposed, yet few have been critically evaluated due to lack of labeled data (data with known identities and quantities). Although labeling techniques exist, they are limited in terms of confidence and accuracy. In silico simulators have recently been used to create complex data ...
Aguiar M M Centro de Matemática e Aplicações Fundamentais da Universidade de - - 2014
SUMMARY Models describing dengue epidemics are parametrized on disease incidence data and therefore high-quality data are essential. For Thailand, two different sources of long-term dengue data are available, the hard copy data from 1980 to 2005, where hospital admission cases were notified, and the electronic files, from 2003 to the ...
Fritah Sabrina S NorLux Neuro-Oncology Laboratory, Department of Oncology, Centre de Recherche Public de la Santé (CRP-Santé), Luxembourg L-1526, - - 2014
The vast majority of the human transcriptome does not code for proteins. Advances in transcriptome arrays and deep sequencing are giving rise to a fast accumulation of large data sets, particularly of long noncoding RNAs (lncRNAs). Although it is clear that individual lncRNAs may play important and diverse biological roles, ...
Yang Tianyu - - 2014
Long term tracking is a challenging task for many applications. In this paper, we propose a novel tracking approach that can adapt various appearance changes such as illumination, motion, and occlusions, and owns the ability of robust reacquisition after drifting. We utilize a condensation-based method with an online support vector ...
Igne Benoît - - 2014
Changes in raw materials and process wear and tear can have significant effects on the prediction error of near-infrared calibration models. When the variability that is present during routine manufacturing is not included in the calibration, test, and validation sets, the long-term performance and robustness of the model will be ...
Shepard Donald S DS Schneider Institutes for Health Policy, Heller School, Brandeis University, Waltham, Massachusetts, United States of - - 2014
Dengue presents a formidable and growing global economic and disease burden, with around half the world's population estimated to be at risk of infection. There is wide variation and substantial uncertainty in current estimates of dengue disease burden and, consequently, on economic burden estimates. Dengue disease varies across time, geography ...
Ashida Yuto Y Department of Physics, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, - - 2014
A general achievable upper bound of extractable work under feedback control is given, where nonequilibrium equalities are generalized so as to be applicable to error-free measurements. The upper bound involves a term which arises from the part of the process whose information becomes unavailable and is related to the weight ...
Fan Zhewen Z a PNC Bank , Pittsburgh , - - 2014
Abstract One of the most challenging aspects of the pharmaceutical development is the demonstration and estimation of chemical stability. It is imperative that pharmaceutical products be stable for two or more years. Long term stability studies are required to support such shelf life claim at registration. However, during drug development ...
Jaxybulatov K K Trofimuk Institute of Petroleum Geology and Geophysics, Siberian Branch of Russian Academy of Sciences, Prospekt Koptyuga, 3, Novosibirsk, 630090 Russia. Novosibirsk State University, 2, Pirogova Street, Novosibirsk 630090, Russia. Institut de Physique du Globe de Paris, Sorbonne Paris Cité, CNRS (UMR 7154), 1 rue Jussieu, 75238 Paris, Cedex 5, - - 2014
An understanding of the formation of large magmatic reservoirs is a key issue for the evaluation of possible strong volcanic eruptions in the future. We estimated the size and level of maturity of one of the largest volcanic reservoirs, based on radial seismic anisotropy. We used ambient-noise seismic tomography below ...
Li Peng P School of Control Science and Engineering, Shandong University, 17923 Jingshi Road, Jinan, 250061, People's Republic of - - 2014
Complexity of heartbeat interval series is typically measured by entropy. Recent studies have found that sample entropy (SampEn) or fuzzy entropy (FuzzyEn) quantifies essentially the randomness, which may not be uniformly identical to complexity. Additionally, these entropy measures are heavily dependent on the predetermined parameters and confined to data length. ...
Tucker Edmonds Brownsyne B Department of Obstetrics and Gynecology, Indiana University School of - - 2014
Abstract Objective: To describe and compare estimates of neonatal morbidity and mortality communicated by neonatologists and obstetricians in simulated periviable counseling encounters. Methods: A simulation-based study of 16 obstetricians (OBs) and 15 neonatologists counseling standardized patients portraying pregnant women with ruptured membranes at 23 weeks gestation. Two investigators tabulated all ...
Engen Steinar S Department of Mathematical Sciences, Center for Biodiversity Dynamics, Norwegian University of Science and Technology, Trondheim N-7491, - - 2014
Abstract There is now considerable empirical evidence that evolutionary changes in many phenotypic characters, such as body mass, age at maturation, and timing of breeding, often occur in populations subject to intense harvesting over longer periods. Here, we analyze the evolutionary component of the selection due to nonselective harvesting, which ...
Ferguson Adam R AR Brain and Spinal Injury Center, Department of Neurological Surgery, University of California at San Francisco, San Francisco, California, - - 2014
The launch of the US BRAIN and European Human Brain Projects coincides with growing international efforts toward transparency and increased access to publicly funded research in the neurosciences. The need for data-sharing standards and neuroinformatics infrastructure is more pressing than ever. However, 'big science' efforts are not the only drivers ...
Worrall Philip P University of Westminster, 101 New Cavendish Street, N7100, London, W1W 6UW, UK, - - 2014
Long-term care (LTC) represents a significant and substantial proportion of healthcare spends across the globe. Its main aim is to assist individuals suffering with more or more chronic illnesses, disabilities or cognitive impairments, to carry out activities associated with daily living. Shifts in several economic, demographic and social factors have ...
Levin Lars-Åke LA Department of Medical and Health Sciences, Linköping University, Linköping, Sweden - - 2014
The purpose of this study was to estimate the cost-effectiveness of two screening methods for detection of silent AF, intermittent electrocardiogram (ECG) recordings using a handheld recording device, at regular time intervals for 30 days, and short-term 24 h continuous Holter ECG, in comparison with a no-screening alternative in 75-year-old ...
Mortezapouraghdam Zeinab - - 2014
In our preliminary work we were able to demonstrate habituation by analyzing attention correlates in singletrial sequences of auditory eventrelated responses (ERPs). Despite dierent quantitative studies of instantaneous phase of ERPs in longterm habituation, there has been no former studies in generative process underlying the distribution of instantaneous phase information ...
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