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 Results 1 - 50 of 1951 1 2 3 4 5 6 7 8 9 10 > 1 Sun Deqiang - - 2014 Bisulfite sequencing (BS-seq) is the gold standard for studying genome-wide DNA methylation. We developed MOABS to increase the speed, accuracy, statistical power and biological relevance of BS-seq data analysis. MOABS detects differential methylation with 10-fold coverage at single-CpG resolution based on a Beta-Binomial hierarchical model and is capable of processing ... 2 Mroczek Dariusz D 1Chair of Motor Activity, University School of Physical Education, Wroclaw, Poland 2Faculty of Physical Education and Physiotherapy, Opole University of Technology, - - 2014 The present study aims to assess motor activity of volleyball players using an original video recording method developed by the authors. 28 volleyball players taking part in four matches of the Polish Volleyball League were examined. The recorded data were analyzed in view of the mean total distance covered by ... 3 Demetrashvili Nino N 1Department of Epidemiology, University Medical Center Groningen, University of Groningen, RB Groningen, the - - 2014 Confidence intervals for intraclass correlation coefficients in agreement studies with continuous outcomes are model-specific and no generic approach exists. This paper provides two generic approaches for intraclass correlation coefficients of the form $$\sum _{q=1}^{Q}{\sigma }_{q}^{2}/(\sum _{q=1}^{Q}{\sigma }_{q}^{2}+\sum _{p=Q+1}^{P}{\sigma }_{p}^{2})$$. The first approach uses Satterthwaite's approximation and an F-distribution. The second ... 4 Meaney Christopher - - 2014 In biomedical research, response variables are often encountered which have bounded support on the open unit interval - (0,1). Traditionally, researchers have attempted to estimate covariate effects on these types of response data using linear regression. Alternative modelling strategies may include: beta regression, variable-dispersion beta regression, and fractional logit regression ... 5 Choi Yongju - - 2014 The validity of a hydrophobic organic contaminant mass transfer model to predict the effectiveness of in-situ AC treatment under stagnant sediment-AC contact is studied for different contaminants and sediments. The modeling results and data from a previous 24-month column study experiment of uptake in polyethylene samplers are within a factor ... 6 Wang Xiaoyan - - 2014 Among the methods of parallel magnetic resonance imaging (PMRI), Generalized Auto-calibrating Partially Parallel Acquisitions (GRAPPA) technique reconstructs the missing k-space data by a set of weights, which are derived from auto-calibration signal (ACS) lines acquired in parallel to the reduced lines. In this paper, a novel hybrid method is proposed ... 7 Martin Andrew A NHS Greater Manchester Commissioning Support Unit, Salford, Manchester, - - 2014 Background: Generic losartan provides an opportunity to enhance angiotensin receptor blocker (ARB) prescribing efficiency, with all ARBs essentially being similar. Initially, there was limited activity in NHS Bury (UK). This changed in March 2011 with therapeutic switching and other measures encouraging the prescribing of losartan following generics to enhance its ... 8 Legendre Pierre P Département de Sciences Biologiques, Université de Montréal, , C.P. 6128, Succursale Centre-ville, Montréal, Québec, Canada , H3C 3J7, Laboratoire des Sciences de l'Environnement Marin (LEMAR), UMR CNRS 6539, Institut Universitaire Européen de la Mer, Université de Bretagne Occidentale, , rue Dumont d'Urville, Plouzané 29280, - - 2014 This review focuses on the analysis of temporal beta diversity, which is the variation in community composition along time in a study area. Temporal beta diversity is measured by the variance of the multivariate community composition time series and that variance can be partitioned using appropriate statistical methods. Some of ... 9 Otani Koichi - - 2014 It has been suggested that interpersonal sensitivity, a personality trait associated with depression and anxiety disorders, is linked with attachment insecurity. To confirm this link, we studied the correlations of interpersonal sensitivity with working models of the self and other. The subjects were 301 healthy Japanese. Interpersonal sensitivity and working ... 10 Montero-Marin Jesus J Faculty of Health Sciences and Sports, University of Zaragoza, Huesca, Spain ; Department of Psychiatry, University of Zaragoza, Zaragoza, Spain ; REDIAPP "Red de Investigación en Actividades Preventivas y Promoción de la Salud" (Research Network on Preventative Activities and Health Promotion), Zaragoza, - - 2014 Burnout occurs when professionals use ineffective coping strategies to try to protect themselves from work-related stress. The dimensions of 'overload', 'lack of development' and 'neglect', belonging to the 'frenetic', 'under-challenged' and 'worn-out' subtypes, respectively, comprise a brief typological definition of burnout. The aim of the present study was to estimate ... 11 Kanoatov Mirzo - - 2013 We describe a mathematical approach that enables extraction of kinetic rate constants from thousands of studies conducted over the past two decades with affinity capillary electrophoresis (ACE). Previously, ACE has been used almost exclusively for obtaining equilibrium constants of intermolecular interactions. In this article, we prove that there exists an ... 12 Noel Yvonnick - - 2013 An unfolding model for continuous bounded responses is proposed, derived both from a hypothetical interpolation response mechanism and from the hypothesis of two opposite sources of item refusal being collapsed. These two sources of refusal are made explicit in a three-component Dirichlet response model and then collapsed to obtain a (two-component) beta response ... 13 Stanga D D National Institute of R&D for Physics and Nuclear Engineering "HoriaHulubei", IFIN-HH, P.O.Box MG-6, Bucharest-Magurele R-077125, Romania. Electronic address: - - 2013 A simple method has been developed for determining the activity of large-area beta reference sources in anodized aluminum foils. It is based on the modeling of the transmission of beta rays through thin foils in planar geometry using Monte Carlo simulation. The method was checked experimentally and measurement results show ... 14 Iknayan Kelly J - - 2013 Estimates of species richness and diversity are central to community and macroecology and are frequently used in conservation planning. Commonly used diversity metrics account for undetected species primarily by controlling for sampling effort. Yet the probability of detecting an individual can vary among species, observers, survey methods, and sites. We ... 15 Havelka Miroslav M Czech Metrology Institute, Inspectorate for Ionizing Radiation, Radiová 1, 102 00 Prague, Czech Republic. Electronic address: - - 2013 The activity of the radionuclide (64)Cu was determined by the efficiency extrapolation method applied to 4π(PC)-γ coincidence counting. The standardisation was performed by software coincidence counting-a digital method for primary activity measurement that simplifies the setting of optimal coincidence parameters. The γ-ray-energy window, characterised by identical gamma detection efficiency related ... 16 Lee Chang-Hyun - - 2013 The sylvian arachnoid cyst (AC) is a common benign disease; however, it sometimes leads to subdural or intracystic hemorrhage without major trauma. The reason of easy bleeding of the AC is not fully understood. The purpose of this study was to investigate the bleeding mechanism of the sylvian AC in ... 17 Hardy J C - - 2013 Because of angular-momentum conservation, superallowed β decay between 0(+) analog states involves only the vector part of the weak interaction, so its measured ft value can be used to determine the vector coupling constant, GV. If many such transitions are measured, then the constancy of GV can be established and ... 18 Battisti Sabrina - - 2013 In May 2005, beta-hexachlorocyclohexane (β-HCH) was found in a sample of bovine bulk milk from a farm in the Sacco River valley (Latium region, central Italy). The primary source of contamination was suspected to be industrial discharge into the environment with the Sacco River as the main mean of dispersion. ... 19 Zhou Mingyuan - - 2013 The seemingly disjoint problems of count and mixture modeling are united under the negative binomial (NB) process. A gamma process is employed to model the rate measure of a Poisson process, whose normalization provides a random probability measure for mixture modeling and whose marginalization leads to a NB process for ... 20 He Wenqi - - 2013 We comment on the recent Letter, by Liu et al. [Opt. Lett.38, 1651 (2013)] in which a method to improve the security strength of the asymmetric cryptosystem (ACS) by Qin and Peng [Opt. Lett.35, 118 (2010)] was proposed. However, in accordance with Liu's methodology, we could easily find other more efficient ... 21 Yu Xiaoyi - - 2013 Long-term storage of articular cartilage (AC) has excited great interest due to the practical surgical significance of this tissue. The liquidus-tracking (LT) method developed by Pegg et al. [Cryobiology, 52 (2006) 360-368] for vitreous preservation of AC achieved reasonable survival of post-warming chondrocytes in situ, but the design of the ... 22 Sathyamoorthy Sandeep - - 2013 Accurate prediction of pharmaceutical concentrations in wastewater effluents requires that the specific biochemical processes responsible for pharmaceutical biodegradation be elucidated and integrated within any modeling framework. The fate of three selected beta blockers - atenolol, metoprolol, and sotalol - was examined during nitrification using batch experiments to develop and evaluate ... 23 Carvalho Susana - - 2013 The present study analyses the composition, structure and trophic function of epibenthic assemblages in two artificial reefs (ARs) 16 years after deployment and in nearby natural reefs (NRs), aiming at providing insights on the complementarity between both habitats. Current findings suggest that after 16 years the ARs (concrete blocks), located ... 24 Cisler Josh M - - 2013 Many cognitive and clinical neuroscience research studies seek to determine how contextual factors modulate cognitive processes. In fMRI, hypotheses about how context modulates distributed patterns of information processing are often tested by comparing functional connectivity between neural regions A and B as a function of task condition X and Y, ... 25 Salari Nader - - 2013 The classification of Acute Coronary Syndrome (ACS), using artificial intelligence (AI), has recently drawn the attention of the medical researchers. Using this approach, patients with myocardial infarction can be differentiated from those with unstable angina. The present study aims to develop an integrated model, based on the feature selection and ... 26 Silva M M - - 2014 This paper addresses the local identifiability and sensitivity properties of two classes of Wiener models for the neuromuscular blockade and depth of hypnosis, when drug dose profiles like the ones commonly administered in the clinical practice are used as model inputs. The local parameter identifiability was assessed based on the ... 27 Hansson Mari - - 2013 High-throughput screening (HTS) is widely used in the pharmaceutical industry to identify novel chemical starting points for drug discovery projects. The current study focuses on the relationship between molecular hit rate in recent in-house HTS and four common molecular descriptors: lipophilicity (ClogP), size (heavy atom count, HEV), fraction of sp(3)-hybridized ... 28 El Karoui Noureddine N Department of Statistics, University of California, Berkeley, CA 94720, USA. - - 2013 We study regression M-estimates in the setting where p, the number of covariates, and n, the number of observations, are both large, but p ≤ n. We find an exact stochastic representation for the distribution of β = argmin(β∈ℝ(p)) Σ(i=1)(n) ρ(Y(i) - X(i')β) at fixed p and n under various ... 29 Comas J - - 2013 Field trials may be required to assess risks of genetically modified crops (GMCs) for nontarget arthropods. One critical point of these trials is their capacity to detect differences between the density of one taxon in the GMC and that in the comparator. The detection capacity of a trial depends on ... 30 Kuss Oliver - - 2013 There are still challenges when meta-analyzing data from studies on diagnostic accuracy. This is mainly due to the bivariate nature of the response where information on sensitivity and specificity must be summarized while accounting for their correlation within a single trial. In this paper, we propose a new statistical model ... 31 Tan Vincent Y F - - 2013 This paper addresses the estimation of the latent dimensionality in nonnegative matrix factorization (NMF) with the $(\beta)$--divergence. The $(\beta)$-divergence is a family of cost functions that includes the squared euclidean distance, Kullback-Leibler (KL) and Itakura-Saito (IS) divergences as special cases. Learning the model order is important as it is necessary ... 32 Legendre Pierre - - 2013 Beta diversity can be measured in different ways. Among these, the total variance of the community data table Y can be used as an estimate of beta diversity. We show how the total variance of Y can be calculated either directly or through a dissimilarity matrix obtained using any dissimilarity ... 33 Yang Lingling - - 2013 Studies have shown that statistically there are differences in theta, alpha and beta band powers when people look at blue and red colors. In this paper, a game has been developed to test whether these statistical differences are good enough for online Brain Computer Interface (BCI) application. We implemented a ... 34 Horoi M - - 2013 Neutrinoless double beta decay, if observed, could distinguish whether the neutrino is a Dirac or a Majorana particle, and it could be used to determine the absolute scale of the neutrino masses. ^{136}Xe is one of the most promising candidates for observing this rare event. However, until recently there were ... 35 El Kerdawy Ahmed - - 2013 We have used a set of four local properties based on semiempirical molecular orbital calculations (the electron density (ρ), hydrogen bond donor field (HDF), hydrogen bond acceptor field (HAF) and molecular lipophilicity potential (MLP)) for 3D-QSAR studies to overcome the limitations of the current force-field based molecular interaction fields (MIFs). ... 36 Xu Xu Steven - - 2013 Beta regression models have been recommended for continuous bounded outcome scores that are often collected in clinical studies. Implementing beta regression in NONMEM presents difficulties since it does not provide gamma functions required by the beta distribution density function. The objective of the study was to implement mixed-effects beta regression ... 37 Srinivas Nuggehally R - - 2013 Ciclesonide, a novel glucocorticosteroid, through a rapid metabolism to desisobutyryl-ciclesonide (des-ciclesonide), provides an effective treatment option for asthma episodes by the inhaled route of administration. The availability of pharmacokinetic parameters (clearance [CL/F]; volume of distribution [Vd/F]; elimination half-life [T1/2]; and elimination rate constant [Kel]) in mice, rats, rabbits, and dogs ... 38 Tulupyev Alexander - - 2013 Our aim is to model the frequency of certain behavioral acts, especially those that are likely to transmit communicable diseases between persons. We develop a generalized linear model on the basis of the beta prime distribution to model the responses to a survey question of the form, 'When was the ... 39 Domenech de Cellès Matthieu - - 2013 BACKGROUND: Extended-spectrum beta-lactamase--producing Enterobacteriaceae (ESBL-E) are a growing concern in hospitals and the community. How to control the nosocomial ESBL-E transmission is a matter of debate. Contact isolation of patients has been recommended but evidence supporting it in non-outbreak settings has been inconclusive. METHODS: We used stochastic transmission models to ... 40 Boot Maikel - - 2013 BACKGROUND: Genes encoding Extended Spectrum Beta Lactamases are usually located on transferable plasmids. Each plasmid contains its own replication mechanism. Carattoli et al. developed an extended PCR-based replicon typing method to characterize and identify the replicons of the major plasmid incompatibility groups in Enterobacteriaceae. Based on this method, we designed ... 41 Moorthy N S Hari Narayana - - 2013 Abstract In the present computational analysis, pharmacophore-based active conformer selection method was used to derive active conformers for the physicochemical descriptors calculation. The significant regression models were validated using different validation methods, which provided significant Q(2) values. The distance-based approaches were also used to analyze the discriminant property of the ... 42 Rocha J Leonel - - 2013 In this work a new probabilistic and dynamical approach to an extension of the Gompertz law is proposed. A generalized family of probability density functions, designated by Beta • (p,q), which is proportional to the right hand side of the Tsoularis-Wallace model, is studied. In particular, for p=2, the investigation ... 43 Vojniković Bozo - - 2013 The authors discussed about the problem of special form in astigmatism classification. This special type of astigmatism is the form of obliquely crossed astigmatism. In which the meridians, major and minor, are not right angles. In this astigmatism is not possible to prescribing for cylindrical (toric) spectacle lens. Authors describe ... 44 Liu Chuan-Fen - - 2013 OBJECTIVE: To illustrate how the analysis of bimodal U-shaped distributed utilization can be modeled with beta-binomial regression, which is rarely used in health services research. DATA SOURCES/STUDY SETTING: Veterans Affairs (VA) administrative data and Medicare claims in 2001-2004 for 11,123 Medicare-eligible VA primary care users in 2000. STUDY DESIGN: We ... 45 Huillet Thierry E - - 2013 We study a class of coalescents derived from a sampling procedure out of [Formula: see text] i.i.d. Pareto[Formula: see text] random variables, normalized by their sum, including [Formula: see text] -size-biasing on total length effects ([Formula: see text]). Depending on the range of [Formula: see text] we derive the large ... 46 Steinrücken Matthias - - 2013 We apply recently developed inference methods based on general coalescent processes to DNA sequence data obtained from various marine species. Several of these species are believed to exhibit so-called shallow gene genealogies, potentially due to extreme reproductive behaviour, e.g. via Hedgecock's "reproduction sweepstakes". Besides the data analysis, in particular the inference ... 47 Schmidt Philip J - - 2013 Dose-response models are the essential link between exposure assessment and computed risk values in quantitative microbial risk assessment, yet the uncertainty that is inherent to computed risks because the dose-response model parameters are estimated using limited epidemiological data is rarely quantified. Second-order risk characterization approaches incorporating uncertainty in dose-response model ... 48 Bordonali L - - 2013 We present a systematic experimental comparison of the superparamagnetic relaxation time constants obtained by means of dynamic magnetic measurements and (1)H-NMR relaxometry, on ferrite-based nanosystems with different composition, various core sizes and dispersed in different solvents. The application of a heuristic model for the relaxivity allowed a comparison between the ... 49 Jiang Guoqian - - 2013 The beta phase of the 11th revision of International Classification of Diseases (ICD-11) intends to accept public input through a distributed model of authoring. One of the core use cases is to create textual definitions for the ICD categories. The objective of the present study is to design, develop, and ... 50 Chen Rongda - - 2013 Recovery rate is essential to the estimation of the portfolio's loss and economic capital. Neglecting the randomness of the distribution of recovery rate may underestimate the risk. The study introduces two kinds of models of distribution, Beta distribution estimation and kernel density distribution estimation, to simulate the distribution of recovery ... 1 2 3 4 5 6 7 8 9 10 >