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Loncke C C 1INRA,UMR1213 Herbivores,F-63122 - - 2014
For energy feeding systems for ruminants to evolve towards a nutrient-based system, dietary energy supply has to be determined in terms of amount and nature of nutrients. The objective of this study was to establish response equations of the net hepatic flux and net splanchnic release of acetate, butyrate and ...
Liu Jessica J Genomics Research Center, Academia Sinica, Taipei - - 2014
 HBsAg seroclearance is the ultimate serological endpoint in chronic hepatitis B. This study aimed to develop and validate a prediction score for spontaneous HBsAg seroclearance in HBeAg-negative patients with genotype B or C chronic hepatitis B infection.  The development cohort included 2491 untreated participants from the community-based REVEAL-HBV study, who ...
Arnold Andrea A Center for Quantitative Sciences in Biomedicine, North Carolina State University, Campus Box 8213, 2700 Stinson Drive, 308 Cox Hall, Raleigh, NC 27695-8213, USA and Department of Mathematics, North Carolina State University, Campus Box 8205, 2108 SAS Hall, 2311 Stinson Drive, Raleigh, NC 27695-8205, - - 2014
We address the problem of estimating the unknown parameters of a model of tracer kinetics from sequences of positron emission tomography (PET) scan data using a statistical sequential algorithm for the inference of magnitudes of dynamic parameters. The method, based on Bayesian statistical inference, is a modification of a recently ...
Ardoino Ilaria I Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy - - 2014
The interpretation of regression models results can often benefit from the generation of nomograms, 'user friendly' graphical devices especially useful for assisting the decision-making processes. However, in the case of multinomial regression models, whenever categorical responses with more than two classes are involved, nomograms cannot be drawn in the conventional ...
Schwen Lars Ole LO Fraunhofer MEVIS, Universitätsallee 29, 28359 Bremen, Germany. Electronic address: - - 2014
Physiologically realistic geometric models of the vasculature in the liver are indispensable for modelling hepatic blood flow, the main connection between the liver and the organism. Current in vivo imaging techniques do not provide sufficiently detailed vascular trees for many simulation applications, so it is necessary to use algorithmic refinement ...
San Miguel Ramón R Department of Pharmacy, Complejo Hospitalario de Navarra, Pamplona, - - 2014
A new scenario of therapy for chronic hepatitis C (CHC) is being established with the approval of sofosbuvir (SOF). To estimate the cost-effectiveness of SOF-based regimens approved in the Summary of Product Characteristics (SmPC) versus the standard of care for different genotypes and patient populations (naive or pretreated). A Markov ...
Emamjomeh Abbasali A Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran, - - 2014
An estimated 170 million people, approximately 3% of the world population, are chronically infected with the hepatitis C virus (HCV). More than 350 000 deaths are reported annually, which are caused by HCV. HCV, similar to a variety of viruses, causes disease in humans by altering protein-protein interactions within the host ...
Carvalho Neta Raimunda Nonata Fortes RN Department of Chemistry and Biology, State University of Maranhão, Campus Paulo VI, Tirirical, São Luís, MA, 65000-000, Brazil, - - 2014
We present a refinement of our model describing the association between enzyme activity and histopathological lesions in the catfish, Sciades herzbergii from a polluted port. The fish were sampled from a port known to be contaminated with heavy metals and organic compounds and from a natural reserve in São Marcos ...
Coban Mehmet M Turkish General Staff, Surgeon General Office, Ankara, - - 2014
We read with great interest the recently published article by Gao et al. (1). In this study, it was aimed to establish a model to predict antiviral treatment for HBeAg negative chronic hepatitis B (CHB) patients with serum alanine aminotransferase (ALT)≤2 upper limit of normal (ULN) without liver biopsy. In conclusion, ...
Pourbasheer Eslam - - 2014
In this present study, three-dimensional structure activity relationship (3D-QSAR) and 2D-QSAR analyses were performed on the series of compounds as Hepatitis C Virus NS5B polymerase inhibitors using CoMFA, CoMSIA and SW-MLR approaches. CoMFA model with good predictive ability was generated based on training set of 39 compounds and showed satisfactory ...
Engelhardt Alexander - - 2014
In the field of oral and maxillofacial surgery, newly developed laser scalpels have multiple advantagesover traditional metal scalpels. However, they lack haptic feedback. This is dangerous near e.g. nervetissue, which has to be preserved during surgery. One solution to this problem is to train an algorithmthat analyzes the reflected light ...
Lippert Julia F JF a University of Illinois at Chicago , Chicago , - - 2014
ABSTRACT Exposure monitoring data indicate the potential for substantive exposure to laser generated air contaminants (LGAC), however the diversity of medical lasers and their applications limit generalization from direct workplace monitoring. Emission rates of seven previously reported gas-phase constituents of medical laser generated air contaminants (LGAC) were determined experimentally and ...
Sumpio Bauer E - - 2013
Vascular surgery has seen a revolutionary transformation in its approach to peripheral vascular disease over the last 2 decades, fueled by technological innovation and a willingness by the field to adopt these changes. However, the underlying pathology behind critical limb ischemia and the significant rate of unhealed wounds and secondary ...
Kumar Prashant - - 2013
We propose a calibration-free algorithm for retrieval of elemental concentrations using laser-induced breakdown spectroscopy. This is a simple and improved version of other ratio-based algorithms as it needs only one trial parameter to estimate all other concentrations. The present algorithm has been used to estimate the composition of a brass ...
Petraco Ricardo R International Centre for Circulatory Health, National Heart and Lung Institute, Imperial College London and Imperial College Healthcare NHS Trust, London, United Kingdom. - - 2013
This study sought to evaluate the effects of fractional flow reserve (FFR) measurement variability on FFR-guided treatment strategy. Current appropriateness guidelines recommend the utilization of FFR to guide coronary revascularization based on a fixed cut-off of 0.8. This rigid approach does not take into account the intrinsic biological variability of ...
- - 2013
Your chance to help set the direction on surveillance.
Hazrati Oldooz O The University of Texas at Dallas, Richardson, TX, - - 2012
In this article, a new signal-processing algorithm is proposed and evaluated for the suppression of the combined effects of reverberation and noise. The proposed algorithm decomposes, on a short-term basis (every 20 ms), the reverberant stimuli into a number of channels and retains only a subset of the channels satisfying ...
Kienstra Kirsten A - - 2012
While many murine models have been developed to study adult disease, animal research focused on neonatal and pediatric medicine has been limited by the small size of the mouse pups. Several transplantation, injection, and implantation systems have been used to study the function and role of vascular progenitor populations in ...
Yao Wenjuan - - 2011
Abstract Conclusions: During total ossicular replacement surgery, a better auditory functional recovery is obtained when the stapes footplate is retained. Also, the best hearing restoration is obtained when the total ossicular replacement prosthesis (TORP) is placed onto the center of the stapes footplate during operation. Objectives: The effects of TORPs ...
Murphy William J - - 2011
Objective: In 2009, the U.S. Environmental Protection Agency (EPA) proposed an impulse noise reduction rating (NRR) for hearing protection devices based upon the impulse peak insertion loss (IPIL) methods in the ANSI S12.42-2010 standard. This study tests the ANSI S12.42 methods with a range of hearing protection devices measured in ...
Hong Oisaeng - - 2011
BACKGROUND: Noise-induced hearing loss (NIHL) is a major occupational health problem that can be prevented through the use of hearing protection devices (HPDs). PURPOSE: The purpose of this study is to identify significant factors related to firefighters' use of HPDs. METHODS: A total of 404 firefighters from 35 fire departments ...
de Boer Bart - - 2011
In this paper, the acoustic-perceptual effects of air sacs are investigated. Using an adaptive hearing experiment, it is shown that air sacs reduce the perceptual effect of vowel-like articulations. Air sacs are a feature of the vocal tract of all great apes, except humans. Because the presence or absence of ...
Lyman R Lee - - 2011
It has been argued by some neozoologists (those who study living animals) that the palaeozoological record is biased and incomplete (relative to an existing biological community) and therefore should not be consulted for purposes of conservation biology. An article published in a biology journal in 2011 lists numerous reasons why ...
Brummund Martin K - - 2011
Earplugs are a frequently used short-term solution for hearing conservation in the workplace environment. Due to limited auditory comfort, however, workers often only wear them for short periods of time and become prone to hearing loss. An important source of discomfort is the auditory occlusion effect, which expresses itself through ...
Ramani Meena - - 2011
People hear differently and have different aesthetic criteria. Due to a number of these reasons, individuals may prefer different processing parameters for both speech and music. For example, some individuals may prefer more low frequency emphasis and longer reverberation time while listening to music. Alternatively, certain individuals with hearing loss ...
Indermaur Lukas - - 2011
Conservation scientists have noted that conservation managers rarely use scientific information when making decisions. One of the reasons why managers rarely use scientific information may be that conservation scientists rarely provide their knowledge in a way that can directly be used by conservation practitioners. Here we show how quantitative recommendations ...
Jaffe J Christopher - - 2011
Movable onstage features such as over-stage reflector panels, acoustical shell towers, reverberant chamber doors, seating risers, etc. offer a high degree of variability and control over ensemble balance, loudness, and other parameters. Finding the optimal settings for such features is far from trivial and combines many different considerations: quality of ...
Gordon Elmaree - - 2011
Hearing loss is one of the most common occupational injuries in the Department of Defense. One reason is limited access to adequate hearing protection during combat operations. Even if traditional pre-formed foam earplugs are used during combat, approximately 15% of the military population remains unprotected because the pre-formed earplugs do ...
Honey-Rosés Jordi - - 2011
  With the potential expansion of forest conservation programs spurred by climate-change agreements, there is a need to measure the extent to which such programs achieve their intended results. Conventional methods for evaluating conservation impact tend to be biased because they do not compare like areas or account for spatial ...
Viallet Guilhem - - 2011
Due to low cost and simplicity, earplugs are a widespread solution to prevent the problem of hearing loss in the workplace environment. In practice, earplugs often perceived are being uncomfortable and/or do not always perform as desired. The attenuation, based on a laboratory measurement, is often overestimated compared to in ...
Chen Zhangli Z Department of Biomedical Engineering, Medical School, Tsinghua University, Beijing 100084, - - 2011
A model for calculating auditory excitation patterns and loudness for steady sounds for normal hearing is extended to deal with cochlear hearing loss. The filters used in the model have a double ROEX-shape, the gain of the narrow active filter being controlled by the output of the broad passive filter. ...
Rondinini Carlo - - 2011
A global strategy is necessary to achieve the level of coordination, synergy and therefore optimization of resources to achieve the broad goal of conserving mammals worldwide. Key elements for the development of such a strategy include: an institutional subject that owns the strategy; broad conservation goals, quantitative targets derived from ...
Visconti Piero - - 2011
Current levels of endangerment and historical trends of species and habitats are the main criteria used to direct conservation efforts globally. Estimates of future declines, which might indicate different priorities than past declines, have been limited by the lack of appropriate data and models. Given that much of conservation is ...
Rondinini Carlo - - 2011
The huge conservation interest that mammals attract and the large datasets that have been collected on them have propelled a diversity of global mammal prioritization schemes, but no comprehensive global mammal conservation strategy. We highlight some of the potential discrepancies between the schemes presented in this theme issue, including: conservation ...
Collen Ben - - 2011
Under the impact of human activity, global extinction rates have risen a thousand times higher than shown in the fossil record. The resources available for conservation are insufficient to prevent the loss of much of the world's threatened biodiversity during this crisis. Conservation planners have been forced to prioritize their ...
Redford Kent H - - 2011
Although mammals are often seen as important objects of human interest and affection, many are threatened with extinction. A range of efforts have been proposed and much work has been done to try to conserve mammals, but there is little overall understanding of what has worked and why. As a ...
Lavender Danielle - - 2011
The middle ears of seven species of rodents, including four hamster species, were examined under light microscopy and through micro-CT imaging. Hamsters were found to possess a spectrum of ossicular morphologies ranging from something approaching "freely mobile" (Mesocricetus) to something nearer the "microtype" (Cricetulus), although no hamster has an orbicular ...
Jones-Farrand D Todd - - 2011
Selection of a modeling approach is an important step in the conservation planning process, but little guidance is available. We compared two statistical and three theoretical habitat modeling approaches representing those currently being used for avian conservation planning at landscape and regional scales: hierarchical spatial count (HSC), classification and regression ...
Dickman Amy J - - 2011
One of the greatest challenges in biodiversity conservation today is how to facilitate protection of species that are highly valued at a global scale but have little or even negative value at a local scale. Imperiled species such as large predators can impose significant economic costs at a local level, ...
Barrett Christopher B - - 2011
This paper introduces a special feature on biodiversity conservation and poverty traps. We define and explain the core concepts and then identify four distinct classes of mechanisms that define important interlinkages between biodiversity and poverty. The multiplicity of candidate mechanisms underscores a major challenge in designing policy appropriate across settings. ...
Leidner Allison K - - 2011
  Understanding the way in which habitat fragmentation disrupts animal dispersal is key to identifying effective and efficient conservation strategies. To differentiate the potential effectiveness of 2 frequently used strategies for increasing the connectivity of populations in fragmented landscapes-corridors and stepping stones-we combined 3 complimentary methods: behavioral studies at habitat ...
Neitzel Richard L - - 2011
To address questions surrounding noise-induced hearing loss (NIHL) from variable noise, we have been evaluating noise exposures and changes in hearing in a prospective cohort of construction workers (representing eight trades) and controls. In this paper, we develop and explore several long-term exposure estimates for cohort members. We followed cohort ...
Sewall Brent J - - 2011
  Systematic conservation assessment (an information-gathering and prioritization process used to select the spatial foci of conservation initiatives) is often considered vital to conservation-planning efforts, yet published assessments have rarely resulted in conservation action. Conservation assessments may lead more directly to effective conservation action if they are reoriented to inform ...
Ferrite Silvia - - 2011
OBJECTIVE: To estimate the validity of three single questions used to assess self-reported hearing loss as compared to pure-tone audiometry in an adult population. METHODS: A validity study was performed with a random sub-sample of 188 subjects aged 30 to 65 years, drawn from the fourth wave of a population-based ...
Yousefian Nima - - 2011
A novel dual-microphone speech enhancement technique is proposed in the present paper. The technique utilizes the coherence between the target and noise signals as a criterion for noise reduction and can be generally applied to arrays with closely-spaced microphones, where noise captured by the sensors is highly correlated. The proposed ...
Jiang Dingfeng D Department of Biostatistics, University of Iowa, Iowa City, IA 52242-1009, USA. - - 2011
This study focuses on sample size determination in repeated measures studies with multinomial outcomes from multiple factors. In settings where multiple factors have repeated measures, a single subject could have hundreds of observations. Sample size selection may then refer to the number of subjects, the number of levels within a ...
Johnson Earl E - - 2011
Background: Prescriptive methods have been at the core of modern hearing aid fittings for the past several decades. Every decade or so, there have been revisions to existing methods and/or the emergence of new methods that become widely used. In 2001 Byrne et al provided a comparison of insertion gain ...
Ma Guilin - - 2011
Feedback whistling is a severe problem with hearing aids. A typical acoustical feedback path represents a wave propagation path from the receiver to the microphone and includes many complicated effects among which some are invariant or nearly invariant for all users and in all acoustical environments given a specific type ...
Moilanen Atte - - 2011
Pressure on ecosystems to provide various different and often conflicting services is immense and likely to increase. The impacts and success of conservation prioritization will be enhanced if the needs of competing land uses are recognized at the planning stage. We develop such methods and illustrate them with data about ...
Seong Jeong C - - 2011
Environmental noise is a major source of public complaints. Noise in the community causes physical and socio-economic effects and has been shown to be related to adverse health impacts. Noise, however, has not been actively researched in the United States compared with the European Union countries in recent years. In ...
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