Results 101  150 of 2728  
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Miekley Bettina   2013
This investigation analysed the applicability of principal component analysis (PCA), a latent variable method, for the early detection of mastitis and lameness. Data used were recorded on the Karkendamm dairy research farm between August 2008 and December 2010. For mastitis and lameness detection, data of 338 and 315 cows in ...


Chai BianFang   2013
Latent community discovery that combines links and contents of a textassociated network has drawn more attention with the advance of social media. Most of the previous studies aim at detecting densely connected communities and are not able to identify general structures, e.g., bipartite structure. Several variants based on the stochastic ...


Pardo Edison   2013
The construction of an atlas of the human brain connectome, in particular, the cartography of fiber bundles of superficial white matter (SWM) is a complex and unachieved task. Its description is essential for the understanding of human brain function and the study of several pathologies. In this work we applied ...


DuxSantoy Lydia   2013
The cardiac conduction system is divided in different sections that play an important role in the cardiac depolarization sequence and define the morphology of the electrocardiogram. In this study we have built several configurations for each section based on anatomical descriptions. The effect of the morphology of the bundle branches, ...


A programmable analog subthreshold biomimetic model for bidirectional communication with the brain.
Ghaderi Viviane S   2013
In this paper, we present a hardware implementation of a second order Laguerre Expansion of Volterra Kernel (LEV) model with four basis functions. The model is versatile enough to be applied at different abstraction levels (synapse, neuron, or network of neurons) and is implemented with analog building blocks in a ...


Szilagyi Laszlo   2013
In this paper we propose an efficient reformulation of a Markov clustering algorithm, suitable for fast and accurate grouping of protein sequences, based on pairwise similarity information. The proposed modification consists of optimal reordering of rows and columns in the similarity matrix after every iteration, transforming it into a matrix ...


Demir Ali   2013
We consider the problem of clustering neural fiber pathways, produced from diffusion MRI data via tractography, into different bundles. Existing clustering methods often suffer from the burden of computing pairwise fiber (dis)similarities, which escalates quadratically as the number of fiber pathways increases. To address this challenge, we adopt the scenario ...


Crevecoeur Guillaume   2013
This paper proposes a modification of the subspace correlation cost function and the Recursively Applied and Projected Multiple Signal Classification (RAPMUSIC) method for electroencephalography (EEG) source analysis in epilepsy. This enables to reconstruct neural source locations and orientations that are less degraded due to the uncertain knowledge of the head ...


Weiskopf Nicole G   2013
We demonstrate the importance of explicit definitions of electronic health record (EHR) data completeness and how different conceptualizations of completeness may impact findings from EHRderived datasets. This study has important repercussions for researchers and clinicians engaged in the secondary use of EHR data. We describe four prototypical definitions of EHR ...


Laattoe Tariq   2013
Smallscale hyporheic zone (HZ) models often use a spatial periodic boundary (SPB) pair to simulate an infinite repetition of bedforms. SPB's are common features of commercially available multiphysics modeling packages. MODFLOW's lack of this boundary type has precluded it from being effectively utilized in this area of HZ research. We ...


Bentley Lisa Patrick   2013
Several theories predict wholetree function on the basis of allometric scaling relationships assumed to emerge from traits of branching networks. To test this key assumption, and more generally, to explore patterns of external architecture within and across trees, we measure branch traits (radii/lengths) and calculate scaling exponents from five functionally ...


Li Xinye   2013
Consider the revenuemaximizing problem in which a single seller wants to sell k different items to a single buyer, who has independently distributed values for the items with additive valuation. The $$k=1$$ case was completely resolved by Myerson's classical work in 1981, whereas for larger k the problem has been ...


Hajdu Eduardo   2013
This is the first phylogenetic analysis integrating both morphological and molecular data of the sponge suborder Mycalina (Poecilosclerida), which was erected in 1994. A cladistic analysis of morphology supported the monophyly of Cladorhizidae (including Euchelipluma), Guitarridae (excluding Euchelipluma), Isodictyidae, Latrunculiidae, and Podospongiidae but rejected monophyly for Desmacellidae, Esperiopsidae, Hamacanthidae, and ...


McCormack Lacey A   2013
This study was done in preparation for the launch of the National Children's Study (NCS) main study. The goal of this study was to examine the feasibility (completion rates and completeness of data), acceptability, staff time and costeffectiveness of three methods of data collection for the postnatal 3 and 9month ...


Saxena Ankur   2013
In this paper, we present a transform scheme where a secondary transform is applied after the conventional DCT for intra as well as inter prediction residues. Our approach is applicable to any blockbased video codec that employs transforms along the horizontal and vertical direction separably. The secondary transform is applied ...


Noland Robert B   2013
Pedestrian and motor vehicle casualties are analyzed for the State of New Jersey with the objective of determining how the income of an area may be associated with casualties. We develop a maximumlikelihood negative binomial model to examine how various spatially defined variables, including road, income, and vehicle ownership, may ...


Chen ZhiZhong   2013
MOTIVATION: Haplotypes play a crucial role in genetic analysis and have many applications such as gene disease diagnoses, association studies, ancestry inference, etc. The development of DNA sequencing technologies makes it possible to obtain haplotypes from a set of aligned reads originated from both copies of a chromosome of a ...


Davies T Jonathan TJ Department of Biology, McGill University, Montreal, Quebec,   2013
The treeoflife represents the diversity of living organisms. Species extinction and the concomitant loss of branches from the treeoflife is therefore a major conservation concern. There is increasing evidence indicating that extinction is phylogenetically nonrandom, such that if one species is vulnerable to extinction so too are its close relatives. ...


Pang Herbert H Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC 27710,   2013
Highthroughput expression profiling allows simultaneous measure of tens of thousands of genes at once. These data have motivated the development of reliable biomarkers for disease subtypes identification and diagnosis. Many methods have been developed in the literature for analyzing these data, such as diagonal discriminant analysis, support vector machines, and ...


Forman Christopher J   2013
Decorative domains force amyloid fibers to adopt spiral ribbon morphologies, as opposed to the more common twisted ribbon. We model the effect of decorating domains as a perturbation to the relative orientation of β strands in a bilayered extended βsheet. The model consists of minimal energy assemblies of rigid building ...


AgirrezabalTelleria I   2013
Among the furanbased compounds, furfural (FUR) shows interesting properties as buildingblock or industrial solvent. It is produced from pentosanrich biomass via xylose cyclodehydration. The current FUR production makes use of homogeneous catalysts and excessive amounts of steam. The development of greener furfural production and separation techniques implies the use of ...


Marrink Siewert J   2013
The Martini model, a coarsegrained force field for biomolecular simulations, has found a broad range of applications since its release a decade ago. Based on a building block principle, the model combines speed and versatility while maintaining chemical specificity. Here we review the current state of the model. We describe ...


Mattfeldt T   2013
This paper deals with the estimation of the intensity of a planar point process on the basis of a single point pattern, observed in a rectangular window. If the model assumptions of stationarity and isotropy hold, the method of block bootstrapping can be used to estimate the intensity of the ...


Kamisli Fatih   2013
In recent video coding standards, intra prediction of a block of pixels is performed by copying neighbor pixels of the block along an angular direction inside the block. Each block pixel is predicted from only one or few directionally aligned neighbor pixels of the block. Although this is a computationally ...


Oelz Dietmar   2013
A mathematical model in one dimension for a nonsarcomeric actomyosin bundle featuring antiparallel flows of antiparallel Factin is introduced. The model is able to relate these flows to the effect of crosslinking and bundling proteins, to the forces due to myosinII filaments and to external forces at the extreme tips ...


Stadler T   2013
Phylogenetic trees of only extant species contain information about the underlying speciation and extinction pattern. In this review, I provide an overview over the different methodologies that recover the speciation and extinction dynamics from phylogenetic trees. Broadly, the methods can be divided into two classes: (i) methods using the phylogenetic ...


Scotti Luciana   2013
The mosquito Aedes aegypti (Diptera, Culicidae) is the vector of yellow and dengue fever. In this study, chemometric tools, such as, Principal Component Analysis (PCA), Consensus PCA (CPCA), and Partial Least Squares Regression (PLS), were applied to a set of fifty five active compounds against Ae. aegypti larvae, which includes ...


HernandezAguilar R Adriana   2013
Data on chimpanzee (Pan troglodytes) nesting patterns were collected in Issa, Ugalla, western Tanzania. Ugalla is one of the driest, most open, and seasonal habitats inhabited by chimpanzees. We investigated the physical characteristics of nests and trees used for nesting to understand environmental influences on nest building and identify the ...


Ferreira Alexandre F P   2013
We study the adsorption equilibrium isotherms and differential heats of adsorption of hexane isomers on the zeolitic imidazolate framework ZIF8. The studies are carried out at 373 K using a manometric setup combined with a microcalorimeter. We see that the Langmuir model describes well the isotherms for all four isomers ...


Stenroos Matti   2013
The conductivity profile of the head has a major effect on EEG signals, but unfortunately the conductivity for the most important compartment, skull, is only poorly known. In dipole modelling studies, errors in modelled skull conductivity have been considered to have a detrimental effect on EEG source estimation. However, as ...


de Queiroz Kevin   2013
Adopting the perspective of graph theory, Martin et al. (2010) described two kinds of phylogenetic trees, which they termed nodebased and stem or branchbased, that differ with respect to the biological interpretations of their component nodes and branches. After establishing equivalency between the two different kinds of trees in terms ...


Kitsche Andreas   2013
Profile hidden Markov models (HMMs) were used to predict the configuration of secondary alcohols and αmethyl branches of modular polyketides. Based on the configurations of two chiral centers in these polyketides, 78 ketoreductases were classified into four different types of polyketide producers. The identification of positions that discriminate between these ...


Karalis Vangelis   2013
PURPOSE: Unveil the properties of a twostage design (TSD) for bioequivalence (BE) studies. METHODS: A TSD with an upper sample size limit (UL) is described and analyzed under different conditions using Monte Carlo simulations. TSD was split into three branches: A, B1, and B2. The first stage included branches A ...


Gharib Walid H   2013
Positive selection is widely estimated from protein coding sequences by the non synonymous / synonymous ratio ω. Increasingly elaborate codon models are used in a likelihood framework for this estimation. While there is widespread concern about the robustness of the estimation of the ω ratio, more efforts are needed to ...


Hao DaPeng   2013
In order to more accurately describe the fracture process of extensive biological fibers, a fiberbundle model with stickslip dynamics and a variable Young modulus is constructed. In this model, the Young modulus of a fiber is assumed to increase or decrease by multiplying with a changing ratio after local sliding ...


Oliveira W W   2013
In this paper we compare different compression models for authorship attribution. To this end, three different types of compressors, LempelZiv type (GZip), block sorting type (BZip) and statistical type (PPM), along with two different similarity measures were considered in our experiments. Besides, two different attribution methods are analyzed in this ...


Blinded sample size reestimation in superiority and noninferiority trials: bias versus variance ...
Friede Tim   2013
The internal pilot study design allows for modifying the sample size during an ongoing study based on a blinded estimate of the variance thus maintaining the trial integrity. Various blinded sample size reestimation procedures have been proposed in the literature. We compare the blinded sample size reestimation procedures based on ...


Song Xiaofeng X Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China.   2013
In addition to experimental identification of premiRNAs, the computational prediction method is also becoming a hot research spot. Most existing prediction methods are usually excluding those premiRNAs with multiple loops. But as more and more miRNA have been identified, quite a number of miRNA precursor with multiple loops have been ...


Zaghetto A   2013
This paper proposes a hybrid pattern matching/transformbased compression method for scanned documents. The idea is to use regular video interframe prediction as a pattern matching algorithm that can be applied to document coding. We show that this interpretation may generate residual data that can be efficiently compressed by a transformbased ...


Sommer David E   2013
Blocktype lumpedelement models of the vocal folds are widely used for speech investigations due in part to the rich dynamics exhibited over a range of input parameters, particularly for asymmetric tissue properties. While selfconsistent in derivation and application, blocktype models of the vocal fold masses are inherently susceptible to nonphysical ...


Suleymanov Y   2013
A mathematical model is developed to describe and investigate interstitial branching of axonal networks during nervous system development. The model under consideration describes axonal network growth in which the concentration of axon guidance molecules controls axon's growth and interstitial branching from axon shaft. Numerical simulations show that in the model ...


Roscoe Eileen M   2013
Hand mouthing (HM) is a chronic problem in many individuals with intellectual disabilities. Although the prevalence of mouthing has been estimated, data on the frequency, severity, or functions of the behavior were not included. In Study 1, we examined the prevalence and risk of HM. Results obtained from interviews showed ...


Jackman Andrea M   2013
According to the Disaster Mitigation Act of 2000 and subsequent federal policy, local governments are required to have a Hazard Mitigation Plan (HMP) written and approved by the Federal Emergency Management Agency (FEMA) to be eligible for federal mitigation assistance. This policy took effect on November 1, 2004. Using FEMA's ...


Raudys Sarunas   2013
In this paper, we consider using profit/loss histories of multiple automated trading systems (ATSs) as N input variables in portfolio management. By means of multivariate statistical analysis and simulation studies, we analyze the influences of sample size (L) and input dimensionality on the accuracy of determining the portfolio weights. We ...


Antoneli Fernando   2013
In this paper, we revisit and adapt to viral evolution an approach based on the theory of branching process advanced by Demetrius et al. (Bull. Math. Biol. 46:239262, 1985), in their study of polynucleotide evolution. By taking into account beneficial effects, we obtain a nontrivial multivariate generalization of their singletype ...


Crawford Forrest W FW Department of Biostatistics, Yale University, New Haven, CT, USA.   2013
The branching structure of biological evolution confers statistical dependencies on phenotypic trait values in related organisms. For this reason, comparative macroevolutionary studies usually begin with an inferred phylogeny that describes the evolutionary relationships of the organisms of interest. The probability of the observed trait data can be computed by assuming ...


Hon Nicholas   2013
The effect of target probability on detection times is wellestablished: Even when detection accuracy is high, lower probability targets are detected more slowly than higher probability ones. Although this target probability effect on detection times has been wellstudied, one aspect of it has remained largely unexamined: How the effect develops ...


Aichholzer Oswin   2013
Given a set B of n black points in general position, we say that a set of white points W blocks B if in the Delaunay triangulation of [Formula: see text] there is no edge connecting two black points. We give the following bounds for the size of the smallest ...


Long Tao   2013
This paper studies the problem of singlechannel noise reduction in the time domain and presents a blockbased approach where a vector of the desired speech signal is recovered by filtering a frame of the noisy signal with a rectangular filtering matrix. With this formulation, the noise reduction problem becomes one ...


Morgan John W R JW University Chemical Laboratories, Lensfield Road, Cambridge CB2 1EW, United   2013
A model potential for colloidal building blocks is defined with two different types of attractive surface sites, described as complementary patches and antipatches. A Bernal spiral is identified as the global minimum for clusters with appropriate arrangements of three patchantipatch pairs. We further derive a minimalist design rule with only ...


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