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Falkenstein Kristin - - 2014
Defects in human Lyst are associated with the lysosomal disorder Chediak Higashi Syndrome. The absence of Lyst results in the formation of enlarged lysosome related compartments but the mechanism for how these compartments arise is not well established. Two opposing models have been proposed to explain Lyst function. The fission ...
Rho Seungsoo S Ophthalmology, CHA Bundang Medical Center, CHA University, 59 Yatap-ro, Bundang-gu, Seongnam, Seongnam, 463-712, Korea (South), Republic of - - 2014
Purpose:To evaluate the clinical efficacy for early detection of retinal nerve fiber layer (RNFL) defect in Korean population using shifting of normative RNFL thickness database according to vessel position. Methods:RNFL thickness data of one hundred fifty-one healthy eyes (normative group) and 120 validation subjects (validation group; additional healthy control plus ...
Brierley N N Department of Mechanical Engineering , Imperial College London , London SW7 2AZ, - - 2014
In industrial non-destructive evaluation (NDE), it is increasingly common for data acquisition to be automated, driving a recent substantial increase in the availability of data. The collected data need to be analysed, typically necessitating the painstaking manual labour of a skilled operator. Moreover, in automated NDE a region of an ...
Tang Chunlei C School of Pharmaceutical Science, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, - - 2014
The zebrafish-based assay is a widely used animal model system for cardiovascular research. In this study, we investigated the cardiac defects caused by terfenadine and tested the pharmacological response of digoxin to zebrafish with cardiac defects. The study suggested that zebrafish could be a suitable model for phenotype-based screening and ...
Tan Shing Chiang - - 2014
Wafer defect detection using an intelligent system is an approach of quality improvement in semiconductor manufacturing that aims to enhance its process stability, increase production capacity, and improve yields. Occasionally, only few records that indicate defective units are available and they are classified as a minority group in a large ...
Costello John P JP Division of Cardiovascular Surgery, Children's National Health System, Washington, DC, USA The Sheikh Zayed Institute for Pediatric Surgical Innovation, Children's National Health System, Washington, DC, - - 2014
The current educational approach for teaching congenital heart disease (CHD) anatomy to students involves instructional tools and techniques that have significant limitations. This study sought to assess the feasibility of utilizing present-day three-dimensional (3D) printing technology to create high-fidelity synthetic heart models with ventricular septal defect (VSD) lesions and applying ...
House Thomas T Warwick Mathematics Institute, University of Warwick, Coventry,  CV4 7AL, UK, - - 2014
Moment closure on general discrete structures often requires one of the following: (i) an absence of short-closed loops (zero clustering); (ii) existence of a spatial scale; (iii) ad hoc assumptions. Algebraic methods are presented to avoid the use of such assumptions for populations based on clumps and are applied to ...
Neto Rui R Instituto de Engenharia Mecânica e Gestão Industrial (INEGI), Porto, Portugal Faculdade de Engenharia da Universidade do Porto (FEUP), Porto, - - 2014
Facial defects (from neoplasms, trauma, etc.) can be functionally and emotionally devastating. A non-invasive treatment for these defects is the application of external prostheses. Conventionally, these prostheses are fabricated by an anaplastologist through a manual procedure, which is an expensive and time-consuming approach. Current advances in computational and engineering tools ...
Lo Annie A The University of Edinburgh Medical School, Edinburgh, Scotland, - - 2014
To provide an estimate for the burden of neural tube defects (NTD) in low- and middle-income countries (LMIC) and explore potential public health policies that may be implemented. Although effective interventions are available to prevent NTD, there is still considerable childhood morbidity and mortality present in LMIC. A search of ...
Schmit Alexandre A IPR, UMR CNRS 6251, Campus Beaulieu, Université Rennes 1, 35042 Rennes, France. laurent.courbin@univ-rennes1.fr - - 2014
The combination of two drop makers such as flow focusing geometries or ┬ junctions is commonly used in microfluidics to fabricate monodisperse double emulsions and novel fluid-based materials. Here we investigate the physics of the encapsulation of small droplets inside large drops that is at the core of such processes. ...
Craig Ana Paula AP PPGCA, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, 31270-901 Belo Horizonte, MG, Brazil; Department of Agricultural and Biological Engineering, Purdue University, 225 S. University Street, West Lafayette, IN 47907, - - 2014
The quality of the coffee beverage is negatively affected by the presence of defective coffee beans and its evaluation still relies on highly subjective sensory panels. To tackle the problem of subjectivity, sophisticated analytical techniques have been developed and have been shown capable of discriminating defective from non-defective coffees after ...
Valverde Israel I 1 Paediatric Cardiology Unit, Hospital Virgen del Rocio, Seville, - - 2014
Purpose: To explore the use of three-dimensional patient-specific cardiovascular models using rapid prototyping techniques (fused deposition modelling) to improve surgical planning in patients with complex congenital heart disease. Description: Rapid prototyping techniques are used to print accurate three-dimensional replicas of patients' cardiovascular anatomy based on magnetic resonance images using computer-aided ...
Stein Cheryl R CR Department of Preventive Medicine Mount Sinai School of Medicine One Gustave L. Levy Place, Box 1057 New York, NY 10029-6574. Electronic address: - - 2014
Perfluorooctanoate (PFOA) is detectable in umbilical cord blood and amniotic fluid. Some toxicological findings suggest that perfluoroalkyl substances may be teratogenic. Using data from the C8 Health Project, a 2005-2006 survey in a Mid-Ohio Valley community exposed to PFOA through contaminated drinking water, we examined the association between estimated prenatal ...
Akram Nik Ahmad NA The University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan, Malaysia. Electronic address: - - 2014
This work proposes a long range ultrasonic transducers technique in conjunction with an active incremental Support Vector Machine (SVM) classification approach that is used for real-time pipeline defects prediction and condition monitoring. Oil and gas pipeline defects are detected using various techniques. One of the most prevalent techniques is the ...
Anderson Stacy L SL Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N - - 2014
The objective of this study was to compare the bursting strength (BS) and mode of failure (MF) of ventral midline (VM) celiotomies closed with USP 7 polydioxanone (7PD) in 1 or 2 simple continuous sections. A bursting strength model, consisting of inserting and inflating a 200-L polyurethane bladder through a ...
Szolnoki Attila A Institute of Technical Physics and Materials Science, Research Centre for Natural Sciences, Hungarian Academy of Sciences, P.O. Box 49, H-1525 Budapest, - - 2014
Reciprocity is firmly established as an important mechanism that promotes cooperation. An efficient information exchange is likewise important, especially on structured populations, where interactions between players are limited. Motivated by these two facts, we explore the role of facilitators in social dilemmas on networks. Facilitators are here mirrors to their ...
Singla Deepika D Assiatant Professor, Department of Physiotherapy, Adhunik Institute of Education and Research (Chaudhary Charan Singh University) , Uttar Pradesh, India - - 2014
Occurrence of postural defects has become very common now-a-days not only in general population but also in sports persons. There are various methods which can be used to assess these postural defects. These methods have evolved over a period of many years. This paper is first of its kind to ...
Douglas Thomas T Oxford Uehiro Centre for Practical Ethics, Faculty of Philosophy, University of Oxford, Littlegate House, St Ebbes St, Oxford OX1 1PT, - - 2014
Kelly Sorensen defends a model of the relationship between effort and moral worth in which the effort exerted in performing a morally desirable action contributes positively to the action's moral worth, but the effort required to perform the action detracts from its moral worth. I argue that Sorensen's model, though ...
Swiątkowska Beata B From the Department of Occupational and Environmental Epidemiology, Nofer Institute of Occupational Medicine, Łódź, - - 2014
To assess further progression of spirometry parameters among former asbestos-cement plant workers. The following parameters were assessed: forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and the ratio (FEV1/FVC) using a linear regression model with mixed effects. The analysis included 3005 individuals. Spirometrically defined restrictive ventilatory defects ...
Liao Chen - - 2014
Microfluidic lab-on-a-chips have been widely utilized in biochemical analysis and human health studies due to high detection accuracy, high timing efficiency, and low cost. The increasing design complexity of lab-on-a-chips necessitates the computer-aided design (CAD) methodology in contrast to the classical manual design methodology. A key part in lab-on-a-chip CAD ...
Bouzat S S Consejo Nacional de Investigaciones Científicas y Técnicas. FiEstIn, Centro Atómico Bariloche (CNEA), (8400) Bariloche, Río Negro, - - 2014
We analyze the pedestrian evacuation of a rectangular room with a single door considering a lattice gas scheme with the addition of behavioral aspects of the pedestrians. The movement of the individuals is based on random and rational choices and is affected by conflicts between two or more agents that ...
Thompson Alexander E AE Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, - - 2014
We have created an improved xenon interatomic potential for use with existing UO2 potentials. This potential was fit to density functional theory calculations with the Hubbard U correction (DFT + U) using a genetic algorithm approach called iterative potential refinement (IPR). We examine the defect energetics of the IPR-fitted xenon ...
Bol Thijs T Amsterdam Centre for Inequality Studies, University of Amsterdam, The Netherlands. Electronic address: - - 2014
Recent sociological studies argue that wage differentials between occupations are partly attributable to occupational closure. Occupations set up barriers which restrict the supply of occupational labor, thereby generating an economic rent. In this article we study occupational closure in the skilled trades of Germany, where the Trade and Crafts code ...
Jeon Yong-Ju - - 2014
Presently, automatic inspection algorithms are widely used to ensure high-quality products and achieve high productivity in the steelmaking industry. In this paper, we propose a vision-based method for detecting corner cracks on the surface of steel billets. Because of the presence of scales composed of oxidized substances, the billet surfaces ...
Mhatre Siddhita D SD Drexel University, Philadelphia, PA, - - 2014
AbstractAlzheimer's Disease (AD) is an age related neurodegenerative disease characterized by memory loss and decreased synaptic function. Advances in transgenic animal models of AD have facilitated our understanding of this disorder, and have aided in the development, speed, and efficiency of testing potential therapeutics. Recently, we have described the characterization ...
Wertelecki Wladimir W Departments of Medical Genetics, College of Medicine, University of South Alabama, Mobile, AL, 36688, US; OMNI-Net for Children International Charitable Fund, Rivne, Rivne province, 33028, - - 2014
This population-based descriptive epidemiology study demonstrates that rates of conjoined twins, teratomas, neural tube defects, microcephaly, and microphthalmia in the Rivne province of Ukraine are among the highest in Europe. The province is 200 km distant from the Chornobyl site and its northern half, a region known as Polissia, is ...
Ng Selina S Y SS Department of Systems Engineering and Engineering Management (SEEM), City University of Hong Kong, Tat Chee Avenue, Kowloon, Hong Kong, China. - - 2014
In bearing diagnostics using a data-driven modeling approach, a concern is the need for data from all possible scenarios to build a practical model for all operating conditions. This paper is a study on bearing diagnostics with the concurrent occurrence of multiple defect types. The authors are not aware of ...
Cui Laizhong L 0000-0003-1991-290X College of Computer Science and Software Engineering, Shenzhen University, Shenzhen 518060, - - 2014
Due to the defects of all kinds of modularity, this paper defines a weighted modularity based on the density and cohesion as the new evaluation measurement. Since the proportion of the overlapping nodes in network is very low, the number of the nodes' repeat visits can be reduced by signing ...
Jackson Charlotte C Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom; Statistics, Modelling and Economics Department, Public Health England, London, United - - 2014
School closure is a potential intervention during an influenza pandemic and has been investigated in many modelling studies. To systematically review the effects of school closure on influenza outbreaks as predicted by simulation studies. We searched Medline and Embase for relevant modelling studies published by the end of October 2012, ...
Che Z H ZH Department of Industrial Engineering and Management, National Taipei University of Technology, Taipei 10608, - - 2014
In consideration of capacity constraints, fuzzy defect ratio, and fuzzy transport loss ratio, this paper attempted to establish an optimized decision model for production planning and distribution of a multiphase, multiproduct reverse supply chain, which addresses defects returned to original manufacturers, and in addition, develops hybrid algorithms such as Particle ...
Duke Wes - - 2014
Background: Fetal death certificates (FDCs) are the main source of stillbirth surveillance data in the United States, yet previous studies suggest FDCs have incomplete ascertainment. In 2005, the Centers for Disease Control and Prevention (CDC) funded 2 pilot programs to determine the feasibility of expanding existing birth defects surveillance systems ...
Chiu Priscilla Pui Lam PP Division of Pediatric General and Thoracic Surgery, Department of Surgery, The Hospital for Sick Children, University of Toronto , Toronto, ON , - - 2014
In recent decades, new research into the developmental defects and pathophysiological basis of congenital diaphragmatic hernia (CDH) has revealed opportunities for the development of innovative therapies. Importantly, the use of animal models to represent this anomaly in the laboratory has resulted in the discovery of many important genetic, epigenetic, and ...
He Hui H School of Computer Science and Technology, Harbin Institute of Technology, Harbin 150001, - - 2014
Software security defects have a serious impact on the software quality and reliability. It is a major hidden danger for the operation of a system that a software system has some security flaws. When the scale of the software increases, its vulnerability has becoming much more difficult to find out. ...
Crider Krista S KS National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA - - 2014
To determine an optimal population red blood cell (RBC) folate concentration for the prevention of neural tube birth defects. Bayesian model. Data from two population based studies in China. 247 831 participants in a prospective community intervention project in China (1993-95) to prevent neural tube defects with 400 μg/day folic acid ...
Han Wenhua W College of Automation Engineering, Shanghai University of Electric Power, Shanghai 200090, China. - - 2014
In this paper, efficient managing particle swarm optimization (EMPSO) for high dimension problem is proposed to estimate defect profile from magnetic flux leakage (MFL) signal. In the proposed EMPSO, in order to strengthen exchange of information among particles, particle pair model was built. For more efficient searching when facing different ...
- - 2014
[This corrects the article DOI: 10.1371/journal.pone.0098131.].
Pinto Nelangi M NM Departments of Pediatrics, University of - - 2013
The economic implications of strategies to improve prenatal CHD screening in low-risk mothers have not been explored. We performed a cost-effectiveness analysis of different screening methods. We constructed a decision analytic model of CHD prenatal screening strategies (four chamber screen (4C), 4C + outflow, nuchal translucency (NT), or fetal echocardiogram) ...
Brown Benjamin J BJ Quantum Optics and Laser Science, Blackett Laboratory, Imperial College London, Prince Consort Road, London SW7 2AZ, United - - 2013
Defects in topologically ordered models have interesting properties that are reminiscent of the anyonic excitations of the models themselves. For example, dislocations in the toric code model are known as twists and possess properties that are analogous to Ising anyons. We strengthen this analogy by using the topological entanglement entropy ...
Nanda Sunil Kumar SK Associate Professor, Department of Biochemistry, Pondicherry Institute of Medical Sciences , Ganapathichettikulam Kalapet, Pondicherry - 605014, India - - 2013
Laboratory errors are result of a poorly designed quality system in the laboratory. Six Sigma is an error reduction methodology that has been successfully applied at Motorola and General Electric. Sigma (σ) is the mathematical symbol for standard deviation (SD). Sigma methodology can be applied wherever an outcome of a ...
Marinica M-C - - 2013
We have developed empirical interatomic potentials for studying radiation defects and dislocations in tungsten. The potentials use the embedded atom method formalism and are fitted to a mixed database, containing various experimentally measured properties of tungsten and ab initio formation energies of defects, as well as ab initio interatomic forces computed ...
Sim Ki-Bum - - 2013
Experimental animal models are essential for investigation of the pathoembryogenesis, pathophysiology, and management strategy of spinal open neural tube defect (ONTD) and its associated anomalies including Chiari type II malformation. Genetic, chemical/nutrient, and surgical models have been widely used for a variety of purposes. The aim of this article is ...
Pellicanó Diego - - 2013
The systematic use of nondestructive testing assumes a remarkable importance where on-line manufacturing quality control is associated with the maintenance of complex equipment. For this reason, nondestructive testing and evaluation (NDT/NDE), together with accuracy and precision of measurements of the specimen, results as a strategic activity in many fields of ...
Sum John - - 2013
Recently, an analog neural network model, namely Wang's kWTA, was proposed. In this model, the output nodes are defined as the Heaviside function. Subsequently, its finite time convergence property and the exact convergence time are analyzed. However, the discovered characteristics of this model are based on the assumption that there ...
Komeda Masashi - - 2013
Finite element analysis method (FEM) provides suitable methodology to analyze a target with complex shape such as VSP patch. In this study, by employing the FEM, Ito and colleagues showed the importance of using a large patch to eliminate the dead space between the patch and LV endocardium. Intuitionally many ...
Kesharaju Manasa - - 2013
Ceramic tiles, used in body armour systems, are currently inspected visually offline using an X-ray technique that is both time consuming and very expensive. The aim of this research is to develop a methodology to detect, locate and classify various manufacturing defects in Reaction Sintered Silicon Carbide (RSSC) ceramic tiles, ...
Zhang Baozhong - - 2013
Classical theory predicts that branching defects are unavoidable in large dendritic molecules when steric congestion is important. Here we report first experimental evidence of this effect via labelling measurements of an extended homologous series of generations g=1…6 of dendronized polymers. This system exhibits a single type of defect interrogated specifically ...
Vajgel André - - 2013
OBJECTIVES: To systematically review the literature data regarding the critical size defect (CSD) in adult rat calvaria and to determine which defect dimensions could be considered as being critical size. MATERIAL AND METHODS: A literature search was conducted at Ovid Medline and Embase up to July 2012. Studies presenting with ...
Mohapatra Devi Prasad - - 2013
Acquired ear lobe defects are common and varied. Reconstruction of ear lobe is difficult and the purpose of reconstruction is purely cosmetic. A variety of methods have been described for reconstruction of defects of the ear lobule although selecting an appropriate method of reconstruction has been difficult due to lack ...
Peiro Jose L - - 2013
BACKGROUND: This study aimed to assess the feasibility of single-access fetal endoscopy (SAFE) for the management of myelomeningocele (MMC) using intrauterine carbon dioxide as a distension medium in a sheep model. METHODS: This prospective experimental case-control study investigated 12 lamb fetuses that had a myelomeningocele-like defect surgically created on the ...
Englert Jan M - - 2013
We report on the introduction of a systematic method for the quantitative and reliable characterization of covalently functionalized graphene based on Scanning-Raman-Microscopy (SRM). This allows for recording and analyzing several thousands of Raman spectra per sample and straightforward display of various Raman properties and their correlations with each other in ...
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