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Amatruda Claudia M CM *These authors contributed equally to this - - 2014
The implantation of stents has been used to treat coronary artery stenosis for several decades. Although stenting is successful in restoring the vessel lumen and is a minimally invasive approach, the long-term outcomes are often compromised by in-stent restenosis (ISR). Animal models have provided insights into the pathophysiology of ISR ...
Parmar Jiten J From the Leeds General Infirmary, University of - - 2014
Access to the skull base is not new. The different modules of the facial skeleton can be removed to give access to the skull base based on target zones, which were first described by Grime et al in 1991. However, the vertical plane is not considered, and this article adds ...
Vera Candioti Luciana L Laboratorio de Desarrollo Analítico y Quimiometría (LADAQ), Cátedra de Química Analítica I, Facultad de Bioquímica y Ciencias Biológicas, Universidad Nacional del Litoral, C.C. 242, S3000ZAA Santa Fe, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Avda. Rivadavia 1917, CP C1033AAJ, Buenos Aires, - - 2014
A review about the application of response surface methodology (RSM) when several responses have to be simultaneously optimized in the field of analytical methods development is presented. Several critical issues like response transformation, multiple response optimization and modeling with least squares and artificial neural networks are discussed. Most recent analytical ...
Huang Chuan C Department of Mathematics, University of Arizona, Tucson, Arizona, USA; Department of Imaging, Center for Advanced Medical Imaging Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, - - 2014
T2 mapping provides a quantitative approach for focal liver lesion characterization. For small lesions, a biexponential model should be used to account for partial volume effects (PVE). However, conventional biexponential fitting suffers from large uncertainty of the fitted parameters when noise is present. The purpose of this work is to ...
Sonter L J LJ The University of Queensland, Centre for Water in the Minerals Industry, Sustainable Minerals Institute, Brisbane, QLD 4072, Australia. - - 2014
Offsets are a novel conservation tool, yet using them to achieve no net loss of biodiversity is challenging. This is especially true when using conservation offsets (i.e., protected areas) because achieving no net loss requires avoiding equivalent loss. Our objective was to determine if offsetting the impacts of mining achieves ...
Reutlinger Michael M Eidgenössische Technische Hochschule (ETH), Departement Chemie und Angewandte Biowissenschaften, Vladimir-Prelog-Weg 4, 8093 Zürich - - 2014
We present the development and application of a computational molecular de novo design method for obtaining bioactive compounds with desired on- and off-target binding. The approach translates the nature-inspired concept of ant colony optimization to combinatorial building block selection. By relying on publicly available structure-activity data, we developed a predictive ...
Sharma Mayur M Department of Neurosurgery, Louisiana State University Health Science Center, Shreveport, Louisiana, United - - 2014
Background The aim of our study was to compare the area of exposure at the ventral brainstem and petroclival region offered by the Kawase, retrosigmoid transtentorial (RTT), and the retrosigmoid intradural suprameatal (RISA) approaches in cadaveric models. Methods We performed 15 approaches (five each of the Kawase, RISA, and RTT approaches) on ...
Saint-Pierre Louise L 1.Centre de Collaboration Nationale sur les Politiques Publiques et la Santé, Institut National de Santé Publique du Québec, Québec, - - 2014
L'évaluation d'impact sur la santé (EIS) est un courant de pratique qui connaît une popularité croissante partout dans le monde depuis la fin des années 1990. D'abord utilisée dans le cadre des évaluations d'impact environnemental (EIE), elle s'est enrichie des connaissances et des principes portés par le courant des déterminants ...
Zhao Yongxiang - - 2014
We reply to the comment written by Aslam and Güney on our previous paper, Zhao et al. [Opt. Express 19(12), 11605-11614 (2011)]. We maintain that the proposed implementation of the DE algorithm for NIMs optimization in our work is correct, and the mentioned ambiguities in the comment due to the ...
Patel Maulik M Department of Genomics, Xcelris Genomics Research Centre, Ahmadabad, - - 2014
Grapefruit (Citrus pardisi) is a popular citrus fruit that is a cross between a sweet orange and pummelo. This research article focuses on an in silico approach for comparative analysis of C. paradisi green flavedo (GF) and ethylene treated flavedo (ETF) transcriptome data. Our pathway analysis provides comprehensive information of ...
Borchers Svenja - - 2014
During a grasping movement, the maximum grip aperture (MGA) is almost linearly scaled to the dimension of the target along which it is grasped. There is still a surprising uncertainty concerning the influence of the other target dimensions on the MGA. We asked healthy participants to grasp cuboids always along ...
Yu Xiaobing X China Institute of Manufacturing Development, Nanjing University of Information Science & Technology, Nanjing 210044, China ; Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters, Nanjing University of Information Science & Technology, Nanjing 210044, - - 2014
Particle swarm optimization (PSO) and differential evolution (DE) are both efficient and powerful population-based stochastic search techniques for solving optimization problems, which have been widely applied in many scientific and engineering fields. Unfortunately, both of them can easily fly into local optima and lack the ability of jumping out of ...
Chang Zheng Z School of Mathematics, Shandong University, Jinan, Shandong, - - 2014
Transcriptome assembly using RNA-seq data - particularly in non-model organisms has been dramatically improved, but only recently have the pre-assembly procedures, such as sequencing depth and error correction, been studied. Increasing read length is viewed as a crucial condition to further improve transcriptome assembly, but it is unknown whether the ...
Nagy Zoltán T ZT Royal Belgian Institute of Natural Sciences, Joint Experimental Molecular Unit, Rue Vautier 29, 1000 Brussels, Belgium.; Email: - - 2014
The Schouteden's sun snake is the sole representative of its genus, and was originally described by the Belgian herpetologist Gaston-François de Witte as a colubrid, Pelophis schoutedeni (de Witte 1922). Twenty years later, the new generic name Helophis was established by de Witte & Laurent (1942) because the generic name ...
Taeger Andreas A Senckenberg Deutsches Entomologisches Institut (SDEI), Eberswalder Straße 90, 15374 Müncheberg, Germany.; Email: - - 2014
The type specimens of sawflies (Hymenoptera: Symphyta) housed in the Museo Nacional de Ciencias Naturales, Madrid, were examined. Lectotypes are designated and illustrated for the following 32 nominal taxa (preserved in the MNCN collection if not stated otherwise): Tenthredo acutiscutis Konow, 1908; Tenthredo aericeps Konow, 1907; Allantus albipectus Konow, 1907; ...
Gates Michael W MW Systematic Entomology Laboratory, USDA, ARS, PSI, c/o National Museum of Natural History, Washington, D. C. 20013-7012, USA.; Email: - - 2014
Ten Eurytomidae (Hymenoptera) parasitic wasp species described by Jean Brèthes and deposited in the Museo Argentino de Ciencias Naturales in Buenos Aires are treated and their nomenclature stabilized. The condition of the type material is described. Lectotypes are designated for Decatoma cecidosiphaga Brèthes, Prodecatoma parodii Brèthes, Eudecatoma opposita Brèthes, and ...
Košťál Michael M Kotlanova 1A, CZ-628 00 Brno, Czech Republic.; Email: - - 2014
The subgenus Persexarthrus Voss, 1944 of the weevil genus Anthonomus Germar, 1817 is revised. Anthonomus (Persexarthrus) behnei sp. n. is described. A neotype of Bradybatus ornatoides Reitter, 1898 and lectotypes for Anthonomus baudueri var. abeillei Desbrochers des Loges, 1892, A. cyprius Marshall, 1925 and Neobradybatus variabilis Hoffmann, 1963 are designated. ...
Rozo Andrea Morales AM Instituto de Biología, Grupo de Ecología y Evolución de Vertebrados, Universidad de Antioquia, calle 67 No 53-108, Medellín, - - 2014
The department of Antioquia, Colombia, lies in the northwestern corner of South America and provides a biogeographical link among divergent faunas, including Caribbean, Andean, Pacific and Amazonian. Information about the distribution of biodiversity in this area is of relevance for academic, practical and social purposes. This data paper describes the ...
Zhu Jiancheng J Department of Automatic Control, College of Mechatronics and Automation, National University of Defense Technology, Deya Street 109, Changsha 410073, Hunan, China. - - 2014
The Unaided Single Frequency/Single Epoch Global Navigation Satellite System (SF/SE GNSS) model is the most challenging scenario for ambiguity resolution in the GNSS attitude determination application. To improve the performance of SF/SE-GNSS ambiguity resolution without excessive cost, the Micro-Electro-Mechanical System Inertial Measurement Unit (MEMS-IMU) is a proper choice for the ...
Joly Simon S Institut de Recherche en Biologie Végétale, Montreal Botanical Garden, 4101 Sherbrooke East, Montreal, H1X 2B2, - - 2013
Adaptive radiations such as the Darwin finches in the Galapagos or the cichlid fishes from the Eastern African Great Lakes have been a constant source of inspiration for biologists and a stimulus for evolutionary thinking. A central concept behind adaptive radiation is that of evolution by niche shifts, or ecological ...
Bogdanowicz Zbigniew R - - 2013
In this paper, we present a novel optimization algorithm for assigning weapons to targets based on desired kill probabilities. For the given weapons, targets, and desired kill probabilities, our optimization algorithm assigns weapons to targets that satisfy the desired kill probabilities and minimize the overkill. The minimization of overkill assures ...
Zhang You - - 2013
Purpose: To develop a technique to estimate onboard 4D-CBCT using prior information and limited-angle projections for potential 4D target verification of lung radiotherapy.Methods: Each phase of onboard 4D-CBCT is considered as a deformation from one selected phase (prior volume) of the planning 4D-CT. The deformation field maps (DFMs) are solved ...
Brusco Michael J - - 2013
The minimum-diameter partitioning problem (MDPP) seeks to produce compact clusters, as measured by an overall goodness-of-fit measure known as the partition diameter, which represents the maximum dissimilarity between any two objects placed in the same cluster. Complete-linkage hierarchical clustering is perhaps the best-known heuristic method for the MDPP and has ...
Gao Weifeng - - 2013
Multimodal optimization is one of the most challenging tasks for optimization. It requires an algorithm to effectively locate multiple global and local optima, not just single optimum as in a single objective global optimization problem. To address this objective, this paper first investigates a cluster-based differential evolution (DE) for multimodal ...
Hoffmann Errol R - - 2013
Previous research [Hoffmann, E. R. 2011. "Capture of Shrinking Targets." Ergonomics 54 (6): 519-530] reported experiments for capture of shrinking targets where the target decreased in size at a uniform rate. This work extended this research for targets having a shrink-size versus time pattern that of an aircraft receding from ...
Hrotic Steven - - 2013
Van de Vliert associates a greater difference between upper- and lower-class freedoms under less favorable environmental conditions. This pattern is similar to models of the emergence of state-level hierarchies. I argue that Van de Vliert has provided a supportive strand to the history of ancient Near East religion.
Buszman Piotr P - - 2013
This study sought to evaluate vascular drug uptake, distribution and response of second-generation paclitaxel coated balloon (PCB) (Cotavance, MEDRAD Interventional, Indianola, Pennsylvania) and compare it with first-generation technology, containing identical excipient and drug concentration. Original PCB technologies displayed a heterogeneous deposition of crystalline paclitaxel-iopromide inside the balloon folds, whereas second-generation ...
Li Guo-Bo - - 2013
Herein, a combined molecular docking-based and pharmacophore-based target prediction strategy is presented, in which a probabilistic fusion method is suggested for target ranking. Establishment and validation of the combined strategy are described. A target database, termed TargetDB, was firstly constructed, which contains 1105 drug targets. Based on TargetDB, the molecular ...
Pounds Stan - - 2013
Tumors exhibit numerous genomic lesions such as copy number variations, structural variations and sequence variations. It is difficult to determine whether a specific constellation of lesions observed across a cohort of multiple tumors provides statistically significant evidence that the lesions target a set of genes that may be located across ...
Massaro Peter Alexander - - 2013
Purpose: Despite the frequency at which urologists endoscopically estimate lesion size, their accuracy has not been established. Our objectives were to determine the accuracy of cystoscopic and ureteroscopic estimates of lesion size using in vitro models of the urinary tract and to assess potential impacting factors. Materials and Methods: Eleven ...
Turner Brandon M - - 2013
Bayesian estimation has played a pivotal role in the understanding of individual differences. However, for many models in psychology, Bayesian estimation of model parameters can be difficult. One reason for this difficulty is that conventional sampling algorithms, such as Markov chain Monte Carlo (MCMC), can be inefficient and impractical when ...
Hanauer David - - 2013
PURPOSE: We describe an experiment to build a de-identification system for clinical records using the open source MITRE Identification Scrubber Toolkit (MIST). We quantify the human annotation effort needed to produce a system that de-identifies at high accuracy. METHODS: Using two types of clinical records (history and physical notes, and ...
Beccari Andrea R - - 2013
Tools for molecular de novo design are actively sought incorporating sets of chemical rules for fast and efficient identification of structurally new chemotypes endowed with a desired set of biological properties. In this paper, we present LiGen, a suite of programs which can be used sequentially or as stand-alone tools ...
Awunor O A - - 2013
This paper details a practical method for the direct reconstruction of high dose rate (192)Ir source dwell positions in ring applicators using gafchromic film in the treatment planning of brachytherapy cervix patients. It also details the uncertainties associated with such a process. Eight Nucletron interstitial ring applicators-Ø26 mm (×4), Ø30 mm (×3) ...
Abbas Qaisar - - 2013
BACKGROUND/PURPOSE: Computer-aided design (CAD) methods are highly valuable for the analysis of skin lesions using digital dermoscopy due to low rate of diagnostic accuracy of expert dermatologist. In computerized diagnostic methods, automatic border detection is the first and crucial step. METHOD: In this study, a novel unified approach is proposed ...
Zhou Dingyu D Y - - 2013
A model for the combustion of butanol is studied using a recently developed theoretical method for the systematic improvement of the kinetic mechanism. The butanol mechanism includes 1446 reactions, and we demonstrate that it is straightforward and computationally feasible to implement a full global sensitivity analysis incorporating all the reactions. ...
Cai Yiqiao - - 2013
Differential evolution (DE) is a simple and powerful population-based evolutionary algorithm, successfully used in various scientific and engineering fields. Although DE has been studied by many researchers, the neighborhood and direction information is not fully and simultaneously exploited in the designing of DE. In order to alleviate this drawback and ...
Glaister J - - 2013
Melanoma is the most deadly form of skin cancer and it is costly for dermatologists to screen every patient for melanoma. There is a need for a system to assess the risk of melanoma based on dermatological photographs of a skin lesion. However, the presence of illumination variation in the ...
Clarke Kaitlin - - 2013
The fast development of next-generation sequencing technology presents a major computational challenge for data processing and analysis. A fast algorithm, de Bruijn graph has been successfully used for genome DNA de novo assembly; nevertheless, its performance for transcriptome assembly is unclear. In this study, we used both simulated and real ...
Lu Bingxin - - 2013
Transcriptome reconstruction is an important application of RNA-Seq, providing critical information for further analysis of transcriptome. Although RNA-Seq offers the potential to identify the whole picture of transcriptome, it still presents special challenges. To handle these difficulties and reconstruct transcriptome as completely as possible, current computational approaches mainly employ two ...
Khorshid Mohsen - - 2013
We introduce a biophysical model of miRNA-target interaction and infer its parameters from Argonaute 2 cross-linking and immunoprecipitation data. We show that a substantial fraction of human miRNA target sites are noncanonical and that predicted target-site affinity correlates well with the extent of target destabilization. Our model provides a rigorous ...
Pereira Alfredo A - - 2013
De Sousa's comprehensive two-part review of a diversity of contemporary approaches to the study of consciousness is highly welcome. He makes us aware of a proliferation of theoretical and empirical approaches targeting a common theme, but diverging in many ways. He skilfully accomplishes a classification of kinds of approach, identification ...
Chiara Matteo - - 2013
De novo transcriptome characterization from Next Generation Sequencing data has become an important approach in the study of non-model plants. Despite notable advances in the assembly of short reads, the clustering of transcripts into unigene-like (locus-specific) clusters remains a somewhat neglected subject. Indeed, closely related paralogous transcripts are often merged ...
Assaad Wissam - - 2012
During minimally invasive surgical procedures (e.g., needle insertion during interventional radiological procedures), needle-tissue interactions and physiological processes cause tissue deformation. Target displacement is caused by soft-tissue deformation, which results in misplacement of the surgical tool (needle). This study presents a technique to predict target displacement in three-dimensions (3D) by combining ...
Iwama Takanori - - 2012
We study group chase and escape with some fast chasers. In our model chasers look for the nearest target and move to one of the nearest sites in order to catch the target. On the other hand, targets try to escape from the nearest chaser. When a chaser catches a ...
Ferriero Giorgio - - 2012
The aim of this study was to assess the reliability of a smartphone-based application developed for photographic-based goniometry, DrGoniometer (DrG), by comparing its measurement of the knee joint angle with that made by a universal goniometer (UG). Joint goniometry is a common mode of clinical assessment used in many disciplines, ...
Lalpuria Minal - - 2012
AIMS: To investigate the effect of different well sizes and pre-diffusion times at 4°C, on the sensitivity, accuracy and precision of nisin quantification by agar diffusion bioassay. METHODS AND RESULTS: Nisin solution (0.625-125 μg ml(-1) ) was filled in wells (3.5 mm or 7 mm diameter) made on agar plates ...
Wang Hongyuan - - 2012
A modeling and validation method of photometric characteristics of the space target was presented in order to track and identify different satellites effectively. The background radiation characteristics models of the target were built based on blackbody radiation theory. The geometry characteristics of the target were illustrated by the surface equations ...
Li Qian - - 2012
Most existing target acquisition (TA) models neglect the influence of background clutter, which results in inaccurate prediction of TA performance in a complicated environment. In this paper, all the background clutter is first quantitatively characterized by the distribution of edge clutter metric, and its effects on the target detection probability ...
Rudmann Daniel G - - 2012
Adverse toxicologic effects are categorized as chemical-based, on-target, or off-target effects. Chemical-based toxicity is defined as toxicity that is related to the physicochemical characteristics of a compound and its effects on cellular organelles, membranes, and/or metabolic pathways. On-target refers to exaggerated and adverse pharmacologic effects at the target of interest ...
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