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Roth Anthony D AD a Research Department of Clinical, Educational and Health Psychology , University College London , London , - - 2014
Abstract Practitioners transporting psychological therapies from a research context to clinical settings need to know what competences they should demonstrate to maintain congruence with the evidence base. This study explores the validity of a suite of competence frameworks for cognitive behavior therapy (CBT), humanistic, and psychodynamic therapies developed to aid ...
Williams Paul P University of Newcastle, Callaghan, New South Wales, - - 2014
Simultaneously presented signals may be processed in serial or in parallel. One potentially valuable indicator of a system's characteristics may be the appearance of multimodality in the response time (RT) distributions. It is known that standard serial models can predict multimodal RT distributions, but it is unknown whether multimodality is ...
Wenke Rachel R Gold Coast Hospital and Health Service , Gold Coast , - - 2014
The current study explored the clinical feasibility and costs of embedding three different intensive service delivery models for aphasia treatment (computer, group therapy, and therapy with a speech pathology therapy assistant) within three sub-acute facilities. The study employed a two cohort comparison design, with the first cohort (n = 22) ...
Zandbelt Bram B Center for Integrative and Cognitive Neuroscience, Vanderbilt Vision Research Center, Department of Psychology, Vanderbilt University, Nashville, TN - - 2014
Decision-making is explained by psychologists through stochastic accumulator models and by neurophysiologists through the activity of neurons believed to instantiate these models. We investigated an overlooked scaling problem: How does a response time (RT) that can be explained by a single model accumulator arise from numerous, redundant accumulator neurons, each ...
Viennet C C PhD, Research Engineer, Engineering and Cutaneous Biology Laboratory, UMR 1098, University of Franche-Comte, - - 2014
Objective: To describe an in vitro fibrin clot model that could reliably assess the fibrinolytic activity of enzymatic debriding agents for wound care application. Method: A model of a fibrin clot was reconstructed in vitro by mixture of human fibrinogen and (alpha)-thrombin supplemented with factor XIII. These clots were then ...
Thelwell Craig C Biotherapeutics, Haemostasis Section, National Institute for Biological Standards and Control, South Mimms, United - - 2014
Thrombolytic drugs are used for the treatment of thrombotic disorders such as acute myocardial infarction, acute ischemic stroke, and pulmonary embolism. Biological standards are used for potency assignment to the range of fibrinolytic proteins used in thrombolytic therapy. The World Health Organization (WHO) International Standards are primary reference materials, calibrated ...
Salerno Jonathan D JD Graduate Group in Ecology, University of California, Davis, One Shields Avenue, Davis, CA 95616, U.S.A.. - - 2014
A recent discussion debates the extent of human in-migration around protected areas (PAs) in the tropics. One proposed argument is that rural migrants move to bordering areas to access conservation outreach benefits. A counter proposal maintains that PAs have largely negative effects on local populations and that outreach initiatives even ...
Busk Peter K - - 2014
MicroRNAs are small but biologically important RNA molecules. Although different methods can be used for quantification of microRNAs, quantitative PCR is regarded as the reference that is used to validate other methods. Several commercial qPCR assays are available but they often come at a high price and the sequences of ...
McDowell Jillian Marie JM Prohealth Physiotherapy, 124 Kelvin St, Invercargill 9810, New Zealand. Electronic address: - - 2014
Quality technique documentation is integral to the practice of manual therapy, ensuring uniform application and reproducibility of treatment. Manual therapy techniques are described by annotations utilizing a range of acronyms, abbreviations and universal terminology based on biomechanical and anatomical concepts. The various combinations of therapist and patient generated forces utilized ...
Olofsson Jonas K JK Gösta Ekman Laboratory, Department of Psychology, Stockholm University Stockholm, Sweden ; Swedish Collegium of Advanced Study Uppsala, - - 2014
The timing of olfactory behavioral decisions may provide an important source of information about how the human olfactory-perceptual system is organized. This review integrates results from olfactory response-time (RT) measurements from a perspective of mental chronometry. Based on these findings, a new cascade model of human olfaction is presented. Results ...
Sanders Taren T University of Western Sydney, School of Science and Health, Penrith, - - 2014
Accurate, objective measurement is important for understanding adolescents' physical activity (PA) behaviour. When using accelerometry to objectively measure PA, a decision must be made regarding how frequently data is recorded (i.e., epoch length). The purpose of this study was to examine i) PA bout length, and ii) the effect of ...
McCallum Jamie W JW School of Biological Sciences, University of Bristol, Bristol, United Kingdom; Conservation Programmes, Zoological Society of London, Regents Park, London, United - - 2014
Several thousand terrestrial protected areas (PAs) lie on international boundaries. Because international boundaries can be focal points for trade, illegal activity and development, such PAs can be vulnerable to a range of anthropogenic threats. There is an increasing trend towards the erection of international boundary infrastructure (including fences, barriers and ...
Wegmann Martin M Department of Remote Sensing, Remote Sensing and Biodiversity Research Group, University of Wuerzburg, , Wuerzburg, - - 2014
The African protected area (PA) network has the potential to act as a set of functionally interconnected patches that conserve meta-populations of mammal species, but individual PAs are vulnerable to habitat change which may disrupt connectivity and increase extinction risk. Individual PAs have different roles in maintaining connectivity, depending on ...
Brodin N Patrik - - 2013
To present a novel tool that allows quantitative estimation and visualization of the risk of various relevant normal tissue endpoints to aid in treatment plan comparison and clinical decision making in radiation therapy (RT) planning for Hodgkin lymphoma (HL). A decision-support tool for risk-based, individualized treatment plan comparison is presented. ...
Plotnikoff Ronald C - - 2013
Theory-based interventions to promote physical activity (PA) are more effective than atheoretical approaches; however, the comparative utility of theoretical models is rarely tested in longitudinal designs with multiple time points. Further, there is limited research that has simultaneously tested social-cognitive models with self-report and objective PA measures. The primary aim ...
Guo Qian Q Department of Mathematics, Shanghai Normal University, 100 Guilin Road, Shanghai 200234, - - 2013
We propose an algorithm based on cross-entropy to determine parameters of a piecewise linear model, which describes intermittent androgen suppression therapy for prostate cancer. By comparing with clinical data, the parameter estimation for the switched system shows good fitting accuracy and efficiency. We further optimize switching time points for the ...
Boterhoven De Haan Katrina L - - 2013
Abstract Objective: Debates continue over shared factors in therapy processes between different theoretical orientations. By seeking the opinions of practicing clinicians, this study aimed to elucidate the similarities and differences between cognitive-behavioural (CBT), psychodynamic (PDT), and schema therapy (ST) approaches. Method: Forty-eight practitioners aligning with one of the three approaches ...
Wilhelm Stanis Sonja A - - 2013
Examine macro-level associations of youth physical activity (PA) and weight status with availability of outdoor recreation resources (i.e., parkland, forestland, natural preserves, nonmotorized trails, and motorized trails) across counties in Minnesota. Hierarchical regression models examined if availability of recreation resources significantly improved prediction of PA and weight status of 9th ...
Armitage James Michael - - 2013
The main objective of this study was to evaluate the performance and demonstrate the utility of a fugacity-based model of passive air samplers (PAS) designed to simulate the uptake of neutral organic chemicals under variable temperatures, external wind speeds and ambient air concentrations. The model (PAS-SIM) simulates the transport of ...
Mailhot Vega Raymond B - - 2013
Proton therapy has been a hotly contested issue in both scientific publications and lay media. Proponents cite the modality's ability to spare healthy tissue, but critics claim the benefit gained from its use does not validate its cost compared with photon therapy. The objective of this study was to evaluate ...
Hong Li Yan - - 2013
Pyrrolizidine alkaloids (PAs) are a group of heterocyclic phytotoxins present in a wide range of plants. The consumption of PA-containing medicinal herbs or PA-contaminated foodstuffs has long been reported to cause human hepatotoxicity. However, the degrees of hepatotoxicity of different PAs are unknown, which makes it difficult to determine a ...
Pérez-Prieto L A - - 2013
Daily pasture allowance (PA) is defined as the product of pregrazing pasture mass and offered area, and is the major grazing management factor determining pasture utilization per unit area and daily performance of grazing dairy cows. The objective of the present study was to perform a meta-analysis reviewing the effect ...
Beer Andrew - - 2013
Trait Negative Affect (NA) and Positive Affect (PA) are strongly associated with Neuroticism and Extraversion, respectively. Nevertheless, measures of the former tend to show substantially weaker self-other agreement-and stronger assumed similarity correlations-than scales assessing the latter. The current study separated the effects of item content versus format on agreement and ...
Guerbois Chloe - - 2013
Increase in human settlements at the edge of protected areas (PAs) is perceived as a major threat to conservation of biodiversity. Although it is crucial to integrate the interests of surrounding communities into PA management, key drivers of changes in local populations and the effects of conservation on local livelihoods ...
Xiao Yanyu - - 2013
The 2009 influenza A (H1N1) pandemic was mild by historical standards, but was more severe in isolated Canadian Indigenous communities. Oseltamivir was used aggressively for outbreak control in an isolated northern Ontario First Nations community. We used mathematical modeling to quantify the impact of antiviral therapy on the course of ...
Taylor Jeremy M G - - 2013
For patients who were previously treated for prostate cancer, salvage hormone therapy is frequently given when the longitudinal marker prostate-specific antigen begins to rise during follow-up. Because the treatment is given by indication, estimating the effect of the hormone therapy is challenging. In a previous paper we described two methods ...
Lee Jim - - 2013
Aims: To present a generalized model to evaluate health and economic outcomes of targeted drug therapies and associated companion diagnostic tests with two applications. Method: An analytical model and derivatives applied to a nonlinear equation representing the costs and benefits of targeted therapy and associated companion diagnostics is developed. Economic ...
Paddock Susan M SM RAND Corporation, 1776 Main Street, Box 2138, Santa Monica, CA 90401-2138 - - 2013
There are several challenges to testing the effectiveness of group therapy-based interventions in alcohol and other drug use (AOD) treatment settings. Enrollment into AOD therapy groups typically occurs on an open (rolling) basis. Changes in therapy group membership induce a complex correlation structure among client outcomes, with relatively small numbers ...
Rhodes Ryan E - - 2013
The physical activity (PA) intention-behaviour gap is a topic of considerable contemporary research, given that most of our models used to understand physical activity suggest that intention is the proximal antecedent of behavioural enactment. The purpose of this study was to quantify the intention-PA gap at public health guidelines with ...
Miller Jeff - - 2013
We used a general stage-based model of reaction time (RT) to investigate the psychometric properties of mean RTs and experimental effect sizes (i.e., differences in mean RTs). Using the model, formulas were derived for the reliabilities of mean RTs and RT difference scores, and these formulas provide guidance about the ...
Mairani A - - 2013
In the field of radiotherapy, Monte Carlo (MC) particle transport calculations are recognized for their superior accuracy in predicting dose and fluence distributions in patient geometries compared to analytical algorithms which are generally used for treatment planning due to their shorter execution times. In this work, a newly developed MC-based ...
Wei Tony T Johns Hopkins Sleep Disorders Center, Division of Pulmonary & Critical Care Medicine, Johns Hopkins School of Medicine, Baltimore, 5501 Hopkins Bayview Circle, MD 21224, - - 2013
The critical closing pressure (PCRIT), a quantitative assessment of upper airway collapsibility, is derived from pressure flow relationship during sleep. The analytic generation of the pressure flow relationships are non-standardized due to various regression models (linear, spline, median), breath characteristics (flow limited, non-flow limited) or known covariates (sleep stage, body ...
Lesnock Jamie L - - 2013
OBJECTIVE: Radiation can be delivered via four-field box (BOX-RT) or intensity modulated radiation therapy (IMRT). We sought to evaluate the cost-effectiveness (C/E) of IMRT relative to BOX-RT for the treatment of locally advanced cervical cancer. METHODS: A three-year Markov model with eight-week cycles was developed to compare IMRT to BOX-RT. ...
Sutton Jonathan T - - 2013
We investigated ultrasound-enhanced thrombolysis in two whole-blood clot models using a Food and Drug Administration-approved contrast agent (Definity, Lantheus Medical Imaging; Billerica, MA USA) and thrombolytic drug (recombinant tissue-type plasminogen activator [rt-PA]) (Genentech; South San Francisco, CA USA). Porcine venous blood was collected from donor hogs and coagulated in vials ...
Kang Bumjoon - - 2013
PURPOSE: This study developed and tested an algorithm to classify accelerometer data as walking or non-walking using either GPS or travel diary data within a large sample of adults under free-living conditions. METHODS: Participants wore an accelerometer and a GPS unit, and concurrently completed a travel diary for 7 consecutive ...
Page Stephen J - - 2013
Modified constraint induced movement therapy (mCIT) increases paretic upper extremity use and movement in all phases of stroke. Although fundamental to its appropriate implementation, specific details on day to day implementation on this promising family of therapies have not heretofore been published. Consequently, some integral behavioral facets of mCIT may ...
McGowan S E - - 2013
The goal of radiotherapy is to achieve uniform target coverage while sparing normal tissue. In proton therapy, the same sources of geometric uncertainty are present as in conventional radiotherapy. However, an important and fundamental difference in proton therapy is that protons have a finite range, highly dependent on the electron ...
Holbrook Elizabeth A - - 2013
As a first step toward the development of adapted physical activity (PA) programs for adults with visual impairment (VI), the purpose of this study was to determine the time frame needed to reliably estimate weekly PA in adults with VI. Thirty-three adults with VI completed 7 days of pedometer-based PA ...
Anisimov Sergei I - - 2013
Past decades significantly advanced our understanding of Rayleigh-Taylor (RT) mixing. We briefly review recent theoretical results and numerical modelling approaches and compare them with state-of-the-art experiments focusing the reader's attention on qualitative properties of RT mixing.
Fong Simon - - 2013
Earlier on, a conceptual design on the real-time clinical decision support system (rt-CDSS) with data stream mining was proposed and published. The new system is introduced that can analyze medical data streams and can make real-time prediction. This system is based on a stream mining algorithm called VFDT. The VFDT ...
Guthrie Elspeth - - 2013
Abstract This article describes the development of Psychodynamic-Interpersonal Therapy or the Conversational Model of therapy, as it is also known. It includes a brief description of the approach to therapy, a review of the evidence base, and a brief description of qualitative and psychotherapy process research that has been conducted ...
Bhushan Manav M Institute of Biomedical Engineering (Department of Engineering Science), University of Oxford, - - 2013
A comprehensive framework for predicting response to therapy on the basis of heterogeneity in dceMRI parameter maps is presented. A motion-correction method for dceMRI sequences is extended to incorporate uncertainties in the pharmacokinetic parameter maps using a variational Bayes framework. Simple measures of heterogeneity (with and without uncertainty) in parameter ...
Ferguson Neil S NS Department of Civil and Environmental Engineering, University of Strathclyde, Glasgow, Scotland, UK. - - 2013
Obesity and other chronic conditions linked with low levels of physical activity (PA) are associated with deprivation. One reason for this could be that it is more difficult for low-income groups to access recreational PA facilities such as swimming pools and sports centres than high-income groups. In this paper, we ...
Bannish Brittany E - - 2012
Fibrinolysis, the proteolytic degradation of the fibrin fibres that stabilize blood clots, is initiated when tissue-type plasminogen activator (tPA) activates plasminogen to plasmin, the main fibrinolytic enzyme. Many experiments have shown that coarse clots made of thick fibres lyse more quickly than fine clots made of thin fibres, despite the ...
Seabra Ana C - - 2012
BACKGROUND: The Youth Physical Activity Promotion (YPAP) model provides an integrated approach to understanding the predisposing, enabling, and reinforcing factors influencing physical activity (PA) behavior. The purpose of this study was to evaluate an adapted version of the YPAP model for explaining PA among Portuguese schoolchildren. METHODS: A random cross-sectional ...
Umstattd Meyer M Renee - - 2012
BACKGROUND. Accelerometers have become one of the most common methods of measuring physical activity (PA). Thus, validity of accelerometer data reduction approaches remains an important research area. Yet, few studies directly compare data reduction approaches and other PA measures in free-living samples. OBJECTIVE. To compare PA estimates provided by three ...
Bentzen Søren M - - 2012
The International Commission on Radiation Units and Measurements (ICRU) Report Committee on "Bioeffect Modeling and Biologically Equivalent Dose Concepts in Radiation Therapy" is currently developing a comprehensive and consistent framework for radiobiological effect modeling based on the equieffective dose, EQDX(α/β), a concept encompassing BED and EQD2 as special cases.
Tuan Nguyen Dac Minh - - 2012
BACKGROUND. Physical activity (PA) and related energy expenditure (EE) is often assessed by means of a single technique. Because of inherent limitations, single techniques may not allow for an accurate assessment both PA and related EE. The aim of this study was to develop a model to accurately assess common ...
Scruggs Philip W - - 2012
BACKGROUND: The validity of common pedometer steps/min guidelines for 1st through 12th grade physical education physical activity (PA) recommendations (i.e., 33% and 50% PA) was investigated. METHODS: Data sets from previous research, where physical education PA was quantified via pedometry, were combined. Participants (1st-12th grade, N=1,152) with concurrent steps/min and ...
Lev-Tov Hadar - - 2012
Background: In its simplest definition, percutaneous absorption (PA) is the amount of substance that passes through the stratum corneum compared with the amount applied. The study of the PA of substances is relevant to the fields of dermatopharmacology and occupational medicine. The quantity and rate in which a given chemical ...
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