Summary.  My comments on the implication of the vW molecule in down-regulating the immunogenicity of factor VIII.

Comment on: Galan-Moya EM, et al. EMBO Rep 2011; 12:470-6.

A lift-off method for creating multifunctional patterned surfaces has been devised. It entails consecutive pulsed plasmachemical deposition of a reactive bottom layer and a protective top release layer. By way of example, a bottom/top layer combination comprising pulsed plasma deposited poly(glycidyl methacrylate)/poly(pentafluorostyrene) has been shown to display selective adhesive lift-off ...

The endothelial surface glycocalyx layer (SGL) and the basement membrane (BM) are two important components of the blood-brain barrier (BBB). They provide large resistance to solute transport across the BBB in addition to the tight junctions in the cleft between adjacent endothelial cells. Due to their glycosaminoglycan compositions, they carry ...

New functional monomers bearing a methacrylate, a bisphosphonate function and, for most, an internal carboxylate group, were prepared for incorporation into copolymers with adhesive or anticorrosive properties. Methanolysis of some trimethylsilyl bisphosphonate esters not only deprotects the desired bisphosphonate function but also regioselectively cleaves the alkyl ester function without affecting ...

Cyclic AMP produced from membrane receptor complex bound adenylyl cyclases is protective in corneal endothelial cells (CEC). CEC also express soluble adenylyl cyclase (sAC), which is localized throughout the cytoplasm. When activated by HCO(3)(-), cAMP concentration ([cAMP]) increases by ∼50%. Here we ask if cAMP produced from sAC is also ...

Objective: To evaluate the predisposing factors and treatment outcomes of different stages of intrauterine adhesions. Methods: We examined the medical records of women with Asherman syndrome seen during the period of January 2000 to December 2007 at two McGill University teaching hospitals in Montreal. Data retrieved included patient's age, menstrual ...

This article has been produced to review the literature on symptomatic and asymptomatic intrauterine adhesions. Electronic resources including Medline, PubMed, CINAHL, The Cochrane Library (including the Cochrane Database of Systematic Reviews), Current Contents, and EMBASE were searched using the Medical Subject Headings (MeSH), including all subheadings, and the keywords "Asherman ...

There is a growing body of evidence supporting the use of hyaluronan (HA) in patients with adhesive capsulitis of the shoulder, although the mechanisms of the effect have not yet been clarified. This in vitro study examined the effects of HA on glenohumeral synovial/capsular fibroblasts (GSCFs) from patients with adhesive ...

Although labial adhesion is usually a benign disorder in childhood, it may occasionally be misdiagnosed as a severe disorder, causing parental anxiety. The present study was undertaken to analyze the clinical features, treatments employed and their effectiveness in pediatric patients with labial adhesion, with special emphasis on manual separation. We ...

Medical thoracoscopy (MT) is indicated for the investigation of unexplained pleural exudates. Not all MT units create artificial pneumothoraces because of time. Difficult pleural space access and thick fibrous adhesions may prevent MT and pleurodesis, respectively. The potential role of thoracic ultrasound (TUS) pre-MT has not been fully evaluated. We ...

High tension and tissue dislocation caused by wide maxillary clefts could prevent an optimal aesthetic and functional outcome in primary cheilognathoplasty. Many surgical techniques or conservative (orthodontic and orthopaedic) devices have been proposed for the initial management of infants with complete cleft lip and palate to achieve a tension-free repair ...

This report describes a case of a 22-year-old girl who had labial adhesion. Her primary complaints were difficulty voiding and temporary urinary retention during menstruation for 10 years. The patient was evaluated and underwent surgical lysis of labial adhesion under regional anesthesia.

Adhesive capsulitis is characterized by a painful, gradual loss of both active and passive glenohumeral motion resulting from progressive fibrosis and ultimate contracture of the glenohumeral joint capsule. Variable nomenclature, inconsistent reporting of disease staging, and a multitude of different treatments have created a confusing and contradictory body of literature ...

Drainage and diversion of cerebrospinal fluid (CSF) through shunt systems is the most common treatment for hydrocephalus, but complications due to tissue obstruction of the catheter occur in up to 61% of patients. Although shunt systems have undergone limited technological advancements to resist mammalian cell adhesion, there is a need ...

Diagnosis of constrictive pericarditis remains clinically challenging. Untwisting of the left ventricle (LV) is essential for normal LV diastolic function. Echocardiography is able to measure LV twisting mechanics. We designed an animal model of constrictive pericarditis to determine how pericardial-epicardial adhesions impair LV twisting mechanics. In eight open-chest pigs, the ...

A 4-year-old miniature horse experienced intermittent episodes of pyrexia, lethargy, and purulent vaginal discharge following dsytocia. Vaginal endoscopy and transrectal ultrasonography revealed a blind-ending vaginal cavity and distended uterus. Surgical treatment was declined and the mare was euthanized. Post-mortem examination confirmed the diagnosis of pyometra and vaginal adhesions.

Intradural lumbar disc herniation (ILDH) is rare. In this report, authors present 2 cases of ILDHs associated with severe adhesion between the dural sac and posterior longitudinal ligament. In a 40-year-old man, ILDH occurred in association with epidural adhesion due to ossification of the posterior longitudinal ligament (OPLL). In other ...

CONTEXT (BACKGROUND): Lip adhesion is a direct edge approximation without changing lip landmarks or disturbing tissue required for definitive closure. This converts a complete cleft into an incomplete cleft, facilitating and enhancing subsequent definitive lip and nose repair. The study aims to describe our technique of lip adhesion and its ...

OBJECTIVE: Observations during adhesive otitis media (OM) surgery led us to consider that morphometric variations might cause formation of the middle ear cavity with smaller bony boundaries during developmental process. Among the various factors mentioned in the literature, we thought that angle of the petrous bone relative to the midsagittal ...

OBJECTIVE: To assess the trends and outcomes in referrals of 'phimosis for circumcision' to a tertiary care pediatric surgical department. METHODS: This is a prospective study of 100 consecutive children of presumed phimosis referred for circumcision. They were assessed and classified by the senior author as having either preputial adhesions ...

BACKGROUND: Hemothorax has been reported to occur along with spontaneous pneumothorax due to adhesion disruption. Rupture of pleural adhesions spontaneously or after unnoticeable trivial trauma causing massive hemothorax alone is rare. METHODS: We present a series of seven cases of idiopathic massive spontaneous hemothorax due to adhesion disruption, of which ...

BACKGROUND: This study was performed to define the dimensions of the rotator interval (RI) in adhesive capsulitis using magnetic resonance (MR) arthrography preoperatively to clarify and evaluate pathology. METHODS: We performed a retrospective review of a series of 73 shoulders that underwent MR arthrography. The shoulders were grouped according to ...

Adhesive capsulitis is a musculoskeletal condition that has a disabling capability. This review discusses the diagnosis and both operative and nonoperative management of this shoulder condition that causes significant morbidity. Issues related to medications, rehabilitation, and post surgical considerations are discussed.

BACKGROUND AND OBJECTIVE: We aimed to examine the frequency of pleural adhesions and to determine their relationship with pleural tumor burden, pleural fluid (PF) biochemistries, PF cytologic yield, and survival in patients with malignant pleural effusion (MPE). METHODS: We performed retrospective analysis of 540 consecutive patients with MPE who underwent ...

OBJECTIVE: To report a patient with sterility secondary to severe intrauterine adhesions who underwent sonohysterographic (SHG) lysis for recurrent adhesions following hysteroscopic lysis, and achieved tubal patency and natural pregnancy leading to term vaginal delivery. DESIGN: Case report. SETTING: National Hospital Organization Kyoto Medical Center, Kyoto, Japan. PATIENT: A patient ...

BACKGROUND: A nonsurgical intervention, interventional microadhesiolysis, was developed to release adhesions in joints and soft tissues. This paper introduces the procedure and evaluates the efficacy of the intervention for adhesive capsulitis of the shoulder. METHODS: Ten patients (five men and five women) with primary adhesive capsulitis of the shoulder were ...

Adhesive capsulitis is a common problem seen in the general population by orthopedic surgeons. It is a problem that causes patients pain and disability, and symptoms can last up to 2 years and longer. The questions of when and how to treat the frozen shoulder can present challenges. Most treatments ...

BACKGROUND: Labial adhesions are common in young girls and menopausal women. Topical estrogen is the first line of therapy for these adhesions. Based on a systematic literature review, postpartum labial adhesions are uncommon in clinical practice. They are not painful but can prevent patients from resuming normal sexual activity. Topical ...

Abnormal fibroblast proliferation has been implicated in the pathogenesis of adhesive capsulitis. The aim of the study was to examine the effect of fluid aspirated from the glenohumeral joint of patients with adhesive capsulitis on human fibroblast cells. Shoulder aspirate from 15 patients with stage II adhesive capsulitis was obtained ...

PURPOSE: We evaluated the efficacy of 0.05% betamethasone cream for the treatment of pre-pubertal labial adhesions. METHODS: We retrospectively reviewed the records of 19 children with labial adhesions who were treated with betamethasone cream from 6/2001 to 3/2003. Children were treated with 1 to 3 courses of twice-daily 0.05% betamethasone ...

Adhesive capsulitis, or frozen shoulder syndrome, is a condition characterized by gradual loss of active and passive glenohumeral motion. The etiology of adhesive capsulitis is unknown. Treatment methods include supervised benign neglect, physical therapy, intra-articular corticosteroid injections, closed manipulation under anesthesia, arthroscopic capsular release, and open surgical release. Approximately 70% ...

Adhesion of PAH/PSS and PDADMAC/PSS capsules through electrostatic and specific interactions has been investigated using reflective interference contrast microscopy (RICM). Adhesion of capsules via electrostatic interactions was found to be spontaneous and strong. Capsules functionalized with poly(l-lysine)-graft-poly(ethylene glycol) (PLL-g-PEG) did not exhibit significant adhesion (as determined by the adhesion area) ...

To determine the rate of manipulation under anaesthesia (MUA) following distension arthrogram for adhesive capsulitis of the shoulder. Thirty-nine patients (42 shoulders) between 1998 and 2004 were treated with distension arthrogram for adhesive capsulitis diagnosed by the clinical picture of progressive pain and stiffness. Capsular disruption into the subscapular bursa ...

PURPOSE: The purpose of this investigation was to determine the relationship between arthroscopically diagnosed synovitis and adhesions in a population of patients with significant limitation of mandibular opening and temporomandibular joint pain. PATIENTS AND METHODS: Temporomandibular joint arthroscopy was performed on 126 joints in 80 patients (female:male = 5.7:1; mean ...

OBJECTIVE: To determine the accessibility of the coracohumeral ligament (CHL) by ultrasound (US) and to determine CHL thickness in adhesive capsulitis of the shoulder. DESIGN AND PATIENTS: US examinations were carried out in 498 consecutive shoulders of 306 individuals (194 women and 112 men), mean age 47.4 years (range 15-92 ...

Many adverse events have been described in patients treated with highly active antiretroviral therapy (HAART). Recently, among these, adhesive capsulitis of the shoulder has been described in some patients using protease inhibitors. We report our experience with 6 human immunodeficiency virus-positive patients in whom adhesive capsulitis of the shoulder developed ...

OBJECTIVE: To evaluate the diagnostic value of multifrequency tympanometry in otitis media with effusion and adhesive otitis media. METHODS: We selected 50 patients with long standing or recurrent attacks of otitis media with effusion from the outpatient clinic of the Ears, Nose and Throat (ENT) Department, Sohag Medical School, Egypt ...

Labial adhesions after puberty are rare and are usually the result of chronic inflammation, urinary tract infection, hypoestrogenism or surgical procedures leading to vulval trauma. Sexual abuse leading to labial adhesions is extremely rare in girls who have attained menarche. Complete vulval fusion can rarely occur without any evidence of ...

BACKGROUND: Adhesive capsulitis of the ankle is a challenging diagnostic and therapeutic problem. Limited information concerning diagnosis and treatment is available in the musculoskeletal literature. METHODS: This study retrospectively reviewed a series of patients treated with corticosteroid injections or arthroscopic debridement of posttraumatic adhesive capsulitis of the ankle. The Foot ...

The importance of a genitourinary (GU) examination and how to evaluate common GU complaints are discussed. Diagnoses covered include inguinal hernia, hydrocele, varicocele, undescended testis, phimosis, hypospadias, meatal stenosis, penile adhesions, labial adhesions, and vaginal voiding. Developmental considerations and examination tips are addressed.

Thesis (M.A.)--National Taiwan University Graduate Institute of Dentistry

INTRODUCTION: Firm paddle force during defibrillation lowers transthoracic impedance (TTI) and increases transmyocardial current, increasing the chances of successful cardioversion. Current protocols recommend that if defibrillation using the anterior-apical (AA) paddle position fails, the anterior-posterior (AP) position should be used. This generally requires the patient to be placed in the ...

BACKGROUND: Adhesive capsulitis, also termed "frozen shoulder," is controversial by definition and diagnostic criteria that are not sufficiently understood. The clinical course of this condition is considered self-limiting and is divided into three clinical phases. Several treatment methods for adhesive capsulitis have been reported in the literature, none of which ...

Manipulation of the glenohumeral joint with the patient under anesthesia has long been used as a treatment modality for refractory shoulder stiffness. Recently, translational manipulation of the glenohumeral joint under interscalene brachial plexus regional block has been shown to be efficacious in the treatment of adhesive capsulitis and to present ...

Many microbes are surrounded by phagocytosis-inhibiting capsules. We took advantage of the large size of the polysaccharide capsule of the pathogenic yeast Cryptococcus neoformans to examine capsular architecture and the relationship between molecular architecture and the interaction of the capsule with potentially opsonic serum proteins. Our experimental design used complementary ...

The adhesion area and topology of spherical hollow polyelectrolyte shells adhering to flat glass or polyelectrolyte-covered glass surfaces are studied. Strong adhesion is found for anionic poly(sodium 4-styrenesulfonate)-terminated shells on cationic poly(ethylene imine)-covered glass, while no adhesion of those shells on uncoated glass is found. The adhering shells are deformed ...

We report the case of a 70-year-old man with dense pleural adhesions who underwent an excision of a mediastinal bronchogenic cyst by video-assisted thoracoscopic surgery (VATS) through an extrapleural approach. The VATS approach for the diagnostic and therapeutic excision of a mediastinal tumor is easier and safer than an intrapleural ...

OBJECTIVE: To explore the efficacy of capsular distension in the treatment of adhesive capsulitis of the shoulder joint. DESIGN: Prospective study. SETTING: Musculoskeletal clinic. PARTICIPANTS: Twenty-two patients (18 women, 4 men; mean age, 41.3y; range, 29-54y) with adhesive capsulitis of shoulder joint. Nineteen patients had Hannafin stage II and 3 ...

STUDY OBJECTIVE: A review of our experience with the surgical treatment of labial adhesions refractory to medical treatment. DESIGN: Retrospective review. SETTING: University tertiary care hospital same-day surgery center. PARTICIPANTS: Nine prepubertal females, age 3-6 yrs, presenting with thick, symptomatic labial adhesions refractory to medical management. INTERVENTION: All patients underwent ...