Pathological narcissism is associated with significant interpersonal problems, which are unlikely to be acknowledged by narcissistic patients as clinical issues. Although a substantial clinical and theoretical literature deals with narcissism, a succinct overview of core narcissistic interpersonal problems is lacking, particularly in terms of their presentation in clinical settings. This ...

ABSTRACT: Therapeutic management of nonhealing wounds is often a challenging condition. Postlaparotomy wound dehiscence can become a serious problem in patients affected with chronic pain and abdomen distension. In this case report, negative-pressure wound therapy with the Chariker-Jeter method was used to treat a dehiscence in a patient affected with ...

AIM: Simple first aid following a burn injury has been shown to improve outcome. With this in mind, a prospective study was conducted to evaluate the knowledge of burns first aid amongst parents in South Yorkshire, United Kingdom. This information was used to identify which aspects of burn first aid ...

OBJECTIVES: To investigate the pathogenesis of one of the most troublesome conditions following ear surgery, a middle-ear cavity problem. METHODS: Keratinocyte growth factor (KGF) and its receptor (KGFR), the ratio of proliferating epithelial cells using Ki-67, and the extent of infiltration of B cells and T cells were examined immunohistochemically ...

Background  The use of antiretroviral therapy (ART) in AIDS has been associated with lipodystrophic syndrome, which is characterized by metabolic alterations and abnormal corporal fat distribution. Our goal was to describe and evaluate the use of polymethylmethacrylate (PMMA) to treat lipoatrophy in patients with AIDS from Amazonas, Brazil. Methods  Patients ...

Problem-solving interventions are a feature of overall medium secure treatment programmes. However, despite the relevance of such treatment to personality disorder there are few descriptions of such interventions for women. Beneficial effects for women who completed social problem-solving group treatment were evident on a number of psychometric assessments. A treatment ...

This report concerns an AIDS patient presenting systemic and cutaneous manifestations of histoplasmosis. A histopathological and mycological examination of the skin lesion confirmed the diagnosis. In AIDS patients histoplasmosis arises mainly when the T-CD4+ cell count is less than 50 cells/mm3. In such cases, histoplasmosis can be severe and if ...

ABSTRACT: BACKGROUND: The majority of South Africans with a DSM-IV diagnosis receive no treatment for their mental health problems. There is a move to simplify treatment for common mental disorders (CMDs) in order to ease access. Brief problem solving therapy (PST) might fill the treatment gap for CMD's in deprived ...

PURPOSE OF REVIEW: The review highlights the recent advances in the pathogenesis, diagnosis and treatment of AIDS-related primary CNS lymphoma (AIDS-PCNSL). RECENT FINDINGS: The incidence of AIDS-PCNSL has decreased in the era of highly active antiretroviral therapy (HAART). The prognosis has improved and this most probably in relation both with ...

Incontinence-associated dermatitis (IAD) is one of the clinical manifestations of moisture-associated skin damage. It is a common problem in community dwelling patients with faecal and/or urinary incontinence, and IAD management is an important challenge for community nurses. The aim of this practice focused article is to provide a brief update ...

ABSTRACT: INTRODUCTION: Giant condyloma acuminatum, also called a Buschke-Lowenstein tumor, first described in 1925, is a slow-growing, locally aggressive, destructive tumor of the ano-genital region. Scrotal tumors are rare. Reports on giant condyloma acuminatum lesions in patients with HIV and AIDS are surprisingly even rarer. CASE PRESENTATION: In this report, ...

Cancer survivors are at risk of experiencing adverse physical and psychosocial effects of their cancer and its treatment. Both Hodgkin's lymphoma (HL) and non-Hodgkin's lymphoma (NHL) survivors face problems that can affect their health-related quality of life (HRQoL). The authors systematically reviewed the literature on HRQoL among HL and NHL ...

Traditional Chinese medicine (TCM) has become widely used in the treatment of acquired immune deficiency syndrome (AIDS) in China in recent years. In this article, we summarize the recent major developments in human immunodeficiency virus/AIDS (HIV/AIDS) treatment with TCM. The use of TCM is associated with preventing or alleviating HIV-related ...

Psychological treatments are widely used for the management of mental health and behavioural problems in people with intellectual disabilities. The evidence base, including the cost-effectiveness of such interventions, is limited. This editorial explores the current evidence base and analyses its strengths and limitations. The editorial also highlights current problems in ...

ABSTRACT: BACKGROUND: There are increasing expectations on primary care doctors to shoulder a bigger share of care for patients with common dermatological problems in the community. This study examined the learning outcomes of a short postgraduate course in dermatology for primary care doctors. METHODS: A self-reported questionnaire developed by the ...

The above paper considers the state-feedback control problem of fuzzy discrete-event systems (DESs) (FDESs) and gives a necessary and sufficient condition for the existence of a state-feedback controller. In this correspondence paper, after indicating that the problem under consideration is applicable for general DESs, not limited to FDESs, we show ...

For the 2010 Manufacturing Problem, the participants were required to produce a filter that had normal incidence transmittances of 0.001, 0.01, 0.1, and 0.96, respectively, in four separate 60 nm wide bands in the 400 to 700 nm wavelength region. The problem is not unlike those that need to be routinely solved ...

This paper introduces methods used to communicate with participants in the 'Biobank Japan Project (BBJP)', which is a disease-focused biobanking project. The methods and their implications are discussed in the context of the ethical conduct of the biobanking project. Informed consent, which ensures the autonomous decisions of participants, is believed ...

To observe the therapeutic effects of Jingyuankang capsules for leukopenia in AIDS patients. In this randomized double-blind trial, 58 patients orally took Jingyuankang capsule, analog Leucogen tablet and the HAART (highly active anti-retroviral therapy) drugs, and the other 58 patients took Leucogen tablet, analog Jingyuankang capsule and the HAART drugs ...

This report of a survey study presents findings from a sample of 594 persons out of a total of 35,763 treated individuals who voluntarily demanded Ivermectin treatment during a community-based Ivermectin distribution exercise. The distribution, which took place in 2008, was the seventh in the planned ten or more years ...

The study of epidemics is almost non-existent in sociological literature, even though such outbreaks can have detrimental effects on communities. The occurrence of SARS (Severe Acute Respiratory Syndrome) in 2003 provides a rare opportunity to understand the social functioning of a community during the outbreak of an epidemic. To evaluate ...

A valid 1 item screen ("In the past 12 months, have you ever had an issue with your gambling?") is potentially important in both a primary care setting and in research applications where an extended screen is not practical or affordable. Prior research by Thomas et al. (A one item screening ...

We generated a clinically useful data collection form for the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire. This data collection form is designed to aid in measuring change and goal setting. Rasch analysis was used to generate three data collection forms for constructs on the DASH (gross motor, ...

Cerebral toxoplasmosis is an acquired immunodeficiency syndrome (AIDS)-related infection and is one of the causes of CNS mass lesions in AIDS. Toxoplasmosis is the most common cerebral mass lesion encountered in HIV-infected patients, and its incidence has increased markedly since the beginning of the AIDS epidemic. Cerebral toxoplasmosis is associated ...

We study properties of the index J(3), defined as the accuracy, or the maximum correct classification, for a given three-class classification problem. Specifically, using J(3) one can assess the discrimination between the three distributions and obtain an optimal pair of cut-off points c(1)<c(2) in the sense that the sum of ...

Brent Kious has recently attacked several arguments generally adduced to support anti-doping in sports, which are widely supported by the sports medicine fraternity, international sports federations, and international governments. We show that his attack does not succeed for a variety of reasons. First, it uses an overly inclusive definition of ...

Since 1958 more than 80 journal papers from the mainstream ergonomics literature have used either the words 'complex' or 'complexity' in their titles. Of those, more than 90% have been published in only the past 20 years. This observation communicates something interesting about the way in which contemporary ergonomics problems ...

The number of usability problems discovered in a user trial or identified in a heuristic evaluation can never be claimed to be exhaustive. This raises the question of how many usability problems remained undetected. In ergonomics/human factors research this subject matter is often addressed by asking how many participants are ...

SUMMARY: Enumeration of the dense sub-graphs of a graph is of interest in community discovery and membership problems, including dense sub-graphs that overlap each other. Described herein is ODES (Overlapping DEnse Sub-graphs), pthreads parallelized software to extract all overlapping maximal sub-graphs whose densities are greater than or equal to a ...

The claims made for 43 commercial filter 'aids', that they improve the colour discrimination of red-green colour defectives, are assessed for protanomaly and deuteranomaly by changes in the colour spacing of traffic signals (European Standard EN 1836:2005) and of the Farnsworth D15 test. Spectral transmittances of the 'aids' are measured ...

Abstract When genetic algorithms (GAs) are applied to combinatorial problems, permutation representations are usually adopted. As a result, such GAs are often confronted with feasibility and memory-efficiency problems. With the aircraft sequencing problem (ASP) as a study case, this paper reports on a novel binary-representation-based GA scheme for combinatorial problems. ...

IFSCC Magazine, 12 (4) 381-385 (2009) Synopsis This review explores the difficult relationship between sun and skin. The various significant factors in this substantial problem include in particular the gene pool, the cells' physiological conditions, biochemical reactions (e.g. reactive oxygen species), biophysical modifications of aging (e.g. skin slackness) and social ...

Metatarsal lengthening by distraction osteogenesis is a challenging procedure that is associated with various adverse results. This article presents and classifies adverse results arising from metatarsal lengthening. Our premise of classification is that not all adverse results that occur secondary to distraction osteogenesis of the metatarsal are true complications that ...

Aggregate mortality data do not tell us if AIDS mortality is uniformly reduced or if there is spatial differentiation. A total of 2432 male and 1864 female deaths (2000-2004) from AIDS in Chiang Rai are used to detect mortality clusters. Both male and female clusters are more or less in ...

Neuropsychologists are ethically charged with communicating their qualifications and credentials in ways that promote understanding and avoid deception. However, there exist few if any concrete guidelines about how and when to cite qualifications when rendering professional neuropsychological opinions. This article attempts to clarify the issues relevant to the signatory process, ...

Development of effective and safe medication for the treatment of viral infections remains a major challenge for the pharmaceutical industry in the 21st Century. There are numerous problems with the existing antiviral treatments both in terms of their safety and, in some cases, their cost, and they cannot be used ...

The present review highlights the existing monitoring and legislation status of synthetic cannabinoids in "Spice" products and alert research community about the identification and risk assessment problems of these compounds. Available data were collected by various literature search engines. All valuable information about psychoactive properties, safety profile, clinical data and ...

Some things in our environment are not what they seem, and they provide a challenge to theories of concepts that emphasize similarity. Section 1 of my commentary explores a dilemma this situation creates for Machery. Section 2 describes a more general problem for prototype and exemplar theories. Section 3 locates ...

The 3 fundamental and essential responsibilities of leadership--setting a compelling and appealing direction (vision), selecting the right people (talent), and creating and embracing the right set of guiding core values (culture)--are reviewed in the context of the many contributions and leadership legacy of Dr Stanley J. Dudrick, one of the ...

MOTIVATION: Ancestral gene order reconstruction problems, including the median problem, quartet construction, small phylogeny, guided genome halving and genome aliquoting, are NP hard. Available heuristics dedicated to each of these problems are computationally costly for even small instances. RESULTS: We present a data structure enabling rapid heuristic solution to all ...

In this contribution, the authors consider multi-criteria optimisation problems arising from the field of systems biology when both continuous and integer decision variables are involved. Mathematically, they are formulated as mixed-integer non-linear programming problems. The authors present a novel solution strategy based on a global optimisation approach for dealing with ...

The discrete form of the mode filtering problem is considered. The relevant equations constitute a linear inverse problem. Solutions to problems of this type are subject to a well-known trade-off between resolution and precision. But unlike the typical linear inverse problem, the correctly formulated mode filtering problem is subject to ...

In partitioning, clustering, and grouping problems, a typical goal is to group together similar objects, or pixels in the case of image processing. At the same time, another goal is to have each group distinctly dissimilar from the rest and possibly to have the group size fairly large. These goals ...

There is evidence that telephone consultations in general practice are typically shorter than face-to-face consultations and that fewer problems are presented in them. To compare the communicative practices of doctors and patients in face-to-face and telephone consultations, in order to understand the contrasts between the two consulting modes. Conversation analysis. ...

We show that inverse problems with a truncated quadratic regularization are NP-hard in general to solve or even approximate up to an additive error. This stands in contrast to the case corresponding to a finite-dimensional approximation to the Mumford-Shah functional, where the operator involved is the identity and for which ...

"How does consciousness commence?" When Darwin set about developing his evolution theory on his return from the Beagle circumnavigation in 1836, he quickly realized that one major problem was, precisely, the existence of "mind" in a material world. This paper reviews his early struggles with this problem and pursues it ...

Good detection of estrus is critically important in dairy husbandry. Incorrect detection of estrus is related to loss of profit due to extended calving intervals, milk loss, veterinary costs, etc. Detection of estrus remains a major problem despites enormous progress in the knowledge of reproductive physiology of the cow and ...

The leaders at King's Daughters Medical Center in Ashland, KY, firmly believe that solving ED throughput problems must be the responsibility of the entire hospital. They must be on the right track. A recent initiative has slashed the rate of patients who left without being seen from 5% to 0.5%. ...

Dealing with psychosomatic realities often generates narcissistic neurotic resistances in the observer that form an obstacle to carrying out scientific work. The tendencies towards schematization and the enforced investigation of arbitrarily defined objects of study, such as they appear in some theoretical standpoints, are aspects of these resistances. The self-destruction ...

This collection of reviews on biological standardisation has been prepared by leading standardisation scientists with a wealth of expertise in the practical problems associated with standardising measurements in the field of haemostasis and haematology. The breadth of areas covered is significant, including coagulation, fibrinolysis, genetic reference materials and anaemia. The ...