OBJECTIVE: To assess the incidence of the AIDS dementia complex and the presence of HIV I p24 antigen in cerebrospinal fluid in relation to zidovudine treatment. DESIGN: Retrospective study of a consecutive series of patients with AIDS from 1982 to 1988. SETTING: An academic centre for AIDS. PATIENTS: 196 Patients ...

A common complication of acquired immunodeficiency syndrome (AIDS) is being increasingly recognized. Known as AIDS dementia complex, the disorder is characterized by global impairment of intellectual and cognitive functions, personality and behavioral disturbances, and motor dysfunction manifested by impaired speech, gait, and coordination. AIDS dementia complex progresses rapidly and inexorably ...

A 40-year-old male, with established AIDS developed cachexia and dementia. At autopsy opportunistic infections were found. An additional neuropathological finding was Wernicke's encephalopathy. Although malnutrition is common in AIDS patients, it seems that Wernicke's encephalopathy is rare in AIDS. Nevertheless, it is suggested that a therapeutic trial with parenteral thiamine ...

Most scholarly attention to survey results focuses on the answers to the questions asked. When attention is directed to the questions, it usually concerns methodological issues of bias, format, and wording. Scholarly attention has completely ignored the issue of why surveys include questions on some issues and not on others. ...

This article focuses on three aspects of the AIDS crisis as it affects the workplace. First, how does the law describe the rights and duties of employers and employees, including coworkers of a person with AIDS, AIDS-Related Complex, or who is antibody positive; second, given the law, what really is ...

The AIDS dementia complex (ADC) is a frequent complication of advanced HIV infection. In order to better define the neuropsychological character and progression of the ADC, four groups of subjects were studied with a battery of neuropsychological tests: an HIV-seronegative comparison group (n = 20), asymptomatic HIV-seropositive patients (n = ...

It has been recognized that AIDS can present initially as dementia without other neurological or clinical manifestations. In addition, HIV-contaminated blood transfusions in the elderly seem to be underreported. Because of these findings, dementia in the elderly may be misdiagnosed as Alzheimer's disease or other causes of senile dementia. This ...

The AIDS Dementia Complex (ADC) frequently occurs in individuals with Acquired Immunodeficiency Syndrome (AIDS). We report on a clinical series of 33 patients with either AIDS or AIDS-Related Complex (ARC), who were referred for neuropsychological evaluation. This clinical series supports the developing understanding that AIDS spectrum patients often demonstrate impairment ...

Changes in eating and weight are not uncommon in dementia although they have yet to be systematically studied. These changes are of clinical importance since they can seriously affect patients' physical health and they are often a major problem for carers. These changes are also of theoretical interest since certain ...

Retrospective studies of hospitalized patients with the acquired immune deficiency syndrome (AIDS) have indicated that dementia occur in the majority of cases. In order to study the occurrence of dementia among AIDS patients, we conducted a controlled study of 16 unselected cases with a battery of neuropsychological tests known to ...

The histological and ultrastructural findings of subacute spongiform encephalopathy (SSE) are described in the cerebral cortex and basal ganglia of a homosexual patient who died with acquired immune deficiency syndrome (AIDS). It is suggested that SSE, beside the diffuse AIDS leukoencephalopathy, might be another morphological substrate of the AIDS dementia ...

Twenty-nine patients at risk of developing acquired immunodeficiency syndrome (AIDS) presented with cognitive, motor, and behavioral dysfunctions characteristic of the AIDS dementia complex, either preceding or in the absence of major systemic opportunistic infections or neoplasms. Six of these patients were medically well, while the remainder suffered only milder manifestations ...

A number of current issues exist that must be taken into account in the development of a strategy for dealing with the problem of the acquired immunodeficiency syndrome (AIDS) in the United States and throughout the world. Given the complexity of the problem and the fact that the epidemic is ...

The Sun article, "Employers finding that AIDS in the workplace is a managerial nightmare" (April 3), did not accurately portray the status of AIDS in the workplace. The AIDS virus, HTLV III, is transmitted by body fluids, primarily semen and blood, and there is no known risk of transmitting the ...

The authors report a case of encephalitis occurring in a setting consistent with acquired immune deficiency syndrome (AIDS). They point out that AIDS and its complications can mimic psychiatric syndromes, including depression and dementia, or delirium related to illnesses such as alcoholism. Acting out behavior, seen in the present case, ...

An Inventory presenting characteristics useful in the clinical identification of dementia of the Alzheimer type (DAT) is presented. The Inventory includes aphasia, amnesia, abnormal cognition and visuospatial skills, inappropriate lack of concern, and normal motor functions. In a retrospective study of 50 consecutive dementia patients, the DAT Inventory correctly identified ...

The DSM-III diagnostic criteria for dementia can be criticised because they treat dementia as a categorical rather than dimensional disorder, and thus ignore the problem of placing appropriate cutoffs. They are also too broad and may result in diagnostic unreliability because of varying interpretations of the criteria by different diagnosticians. ...

The analysis of the abnormality of the membrane in paroxysmal nocturnal haemoglobinuria is an exercise in complexity complexified--of Ossa atop Pelion. To understand it, we will need to understand fully the complexities of the complement system and the complexities of the structure of the membrane and the complexity of their ...

In this paper I argue for several related theses: first, that the distinction between killing and letting die, as it is drawn by ordinary persons in ordinary contexts, is more complex than is generally understood; second, that the key feature of this complexity lies in the presence of a hidden ...

Is sexual harassment a serious issue for managers, and does it occur as much in business as the popular press would have us believe? How difficult will it be to implement the newly issued EEOC guidelines? Out of a joint survey with Redbook magazine, HBR takes a look at these ...

This fact sheet is one in a series provided by CANDID (Counselling ANd Diagnosis In Dementia), a UK support group based at the National Hospital for Neurology and Neurosurgery. Written by two speech and language therapists, this fact sheet covers the swallowing mechanism, swallowing problems (dysphagia), diet and equipment. Aimed ...

A SCIE research briefing is "a summary of information on a particular topic to update practice at the health and social care interface." This briefing on aiding communication with people with dementia examines relevant issues including the ethical considerations, views of users and user groups, and examples of innovative practice.

It was not until the 1980s that significant research was carried out on brain disorders. Lack of understanding of dementia has perhaps been the reason for the over-emphasis on physical care, and a failure to see these patients as people with feelings, beliefs and values. Three therapeutic techniques to help ...