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Edeline Julien J Medical Oncology Department, Centre Eugène Marquis, Av de la bataille Flandres Dunkerque, 35043, Rennes, France, - - 2014
Sorafenib is the standard of care for advanced hepatocellular carcinoma (HCC). The peak incidence of HCC is around 70 years. We aimed to evaluate safety and efficacy of sorafenib in the elderly population. We retrospectively reviewed data from patients treated with sorafenib for HCC at our institution. We compared safety and ...
O'Connor Ayrn D AD Department of Medical Toxicology, Banner Good Samaritan Medical Center; Department of Internal Medicine, and Center for Toxicology and Pharmacology Education and Research, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA, - - 2014
Synthetic cathinones have emerged as popular drugs of abuse and produce sympathomimetic toxicity. It is unknown if rhabdomyolysis occurs more frequently following the use of synthetic cathinones compared to other stimulants. This retrospective study sought to determine the prevalence of rhabdomyolysis in patients with sympathomimetic toxicity and compare rates among ...
Liourdi Despoina D University of Patras, Urology, Patras, Greece ; - - 2014
The urothelium represents "the tightest and most impermeable barrier in the body". We investigated the distribution of paclitaxel in the ureteral wall after the inflation of a paclitaxel-eluting balloon (PEB) in an attempt to elucidate the possibility of clinical application of PEBs in the ureter. Nine domestic pigs were used. ...
Morgan Juliette J President's Malaria Initiative, Malaria Branch, Centers for Disease Control and Prevention, Atlanta, Georgia; Instituto Nacional da Saúde, Ministério da Saúde, Maputo, Mozambique; Programa Nacional de Controlo da Malária, Ministério da Saúde, Maputo, Mozambique; President's Malaria Initiative, Malaria Branch, Centers for Disease Control and Prevention, Atlanta, Georgia; President's Malaria Initiative, Entomology Branch, Centers for Disease Control and Prevention, Atlanta, - - 2014
We conducted a prospective evaluation to measure the physical durability of two brands of long-lasting insecticidal nets (LLINs) distributed during a campaign in 2008 in Nampula Province, Mozambique. Households with LLINs tagged during the campaign (6,000) were geo-located (34%) and a random sample was selected for each of 3 years ...
Thimmesch M - - 2014
Toxic epidermal necrosis is a severe mucocutaneous disease with a high mortality rate. A third of the patients surviving the acute phase will develop pulmonary complications. The most frequent complication is bronchiolitis obliterans. Despite well-conducted treatment, in most cases, lung injury often leads to chronic respiratory failure. We describe here ...
Williams Gavin G Physiotherapy Department, University of Melbourne, Australia (Dr Williams) and Physiotherapy Department-Rehabilitation, Epworth Hospital, Melbourne, Australia (Drs Williams and Olver and Ms - - 2014
To examine the association between lower limb spasticity and mobility limitations following traumatic brain injury (TBI) and determine the influence of spasticity distribution on mobility outcomes following TBI. A large metropolitan rehabilitation hospital. Ninety-three ambulant people with TBI who were attending physiotherapy for mobility limitations. Cross-sectional cohort study. The High-Level ...
Keyes Mira M British Columbia Provincial Prostate Brachytherapy Program, British Columbia Cancer Agency, Vancouver, British Columbia, Canada. Electronic address: - - 2014
To determine late urinary toxicity (>12 months) in a large cohort of uniformly treated low-dose-rate prostate brachytherapy patients. From 1998 to 2009, 2709 patients with National Comprehensive Cancer Network-defined low-risk and low-tier intermediate-risk prostate cancer were treated with Iodine 125 ((125)I) low-dose-rate prostate brachytherapy; 2011 patients with a minimum of 25 months ...
Anikwe Joseph Chuks - - 2014
Indoxacarb gel bait was evaluated for its efficacy in the laboratory and field against American cockroaches, Periplaneta americana (L.), and German cockroaches, Blattella germanica (L.). Advion 0.6% indoxacarb gel bait was toxic to both P. americana and B. germanica. There were no significant differences in the LT50 (h) values for ...
Jariwala Pankti P Department of Skin & VD, Government Medical College & New Civil Hospital, Surat, Gujarat 395001, - - 2014
We describe two fatal cases of low dose methotrexate (MTX) toxicity in patients with psoriasis, emphasizing the factors that exacerbate MTX toxicity. The first patient was a 50-year-old male of psoriasis on intermittent treatment with MTX. After a treatment-free period of six months, he had self-medication of MTX along with ...
Costarelli Silvia S Infectious Diseases, San Gerardo Hospital, Monza, - - 2014
In clinical trials, toxicity leading to discontinuation of tenofovir (TDF) is a rare occurrence (3% by two years)[1, 2]; however, in clinical practice it seems to be higher. Previous studies suggested that TDF toxicity is higher when it is co-administered with ritonavir-boosted protease inhibitors (PI/r)[3, 4]. The aim of this ...
Mantz Constantine C 21st Century Oncology , Fort Myers, FL , - - 2014
Purpose/Objective(s): Herein, we report the results of an IRB-approved phase II trial of Varian Trilogy/TrueBeam-based stereotactic ablative body radiotherapy (SABR) monotherapy for low-risk prostate cancer using the Calypso(®) System to provide real-time electromagnetic tracking of the prostate's position during treatment delivery. Materials/Methods: A total of 102 low-risk patients completed protocol ...
Lee Seul Ji SJ College of Pharmacy, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 151-742, - - 2014
Topical steroids are used for the treatment of primary atopic dermatitis (AD); however, their associated risk of serious complications is great due to the presence of vulnerable lesions in young children with AD. Topical calcineurin inhibitors (TCIs) are steroid-free, anti-inflammatory agents used for topical AD therapy. However, their use is ...
Kalra Ankur - - 2012
Eosinophilia in clinical practice can occur due to various pathologic processes. Causes of eosinophilia include idiopathic eosinophilia, reactive eosinophilia, idiopathic hypereosinophilic syndrome (HES), chronic eosinophilic leukemia, and other hematopoietic neoplasms (myeloid, lymphatic, or mast cell). We present a case of a 22-year-old man with HES with remarkable clinical manifestations and ...
Reser D - - 2012
BACKGROUND: Numerous cardiopulmonary bypass circuits with various coatings designed to reduce the inflammatory response and to provide better hemocompatibility are available. The aim of this study was to compare the effect of phosphorylcholine-coated, albumin-heparin-coated and synthetic polymer-coated perfusion tubing systems on patient outcome. METHODS: We performed a retrospective database review ...
Al-Tamimi Yahia Z - - 2012
Introduction. There are many indications for cranioplasty with an increasing incidence partly attributable to an increase in decompressive craniectomy following trauma and stroke. The aim of this study was to compare the survival of acrylic and titanium cranioplasties used in our department. Materials and methods. Retrospective cohort study of 126 ...
Lear Aaron M - - 2012
These evaluative methods can help you optimize a patient's treatment and return to activity.
Rajaee Sean S - - 2012
The purpose of this study was to present national trends in primary total hip arthroplasty (THA) and bearing surface usage for patients 30 years and younger. Using the Healthcare-Cost-and-Utilization-Project Nationwide Inpatient Sample for the years 2006 to 2009, 8919 primary THA discharges (4454 coded by bearing surface) were identified in ...
Talarico Giovanni Paolo - - 2012
BACKGROUND: Polymer-coating represents a key component of drug-eluting stent (DES) technology and its possible impact on vessel-wall healing is a matter of debate. The clinical impact of different polymer-coating may be assessed by comparing the outcome of patients treated by DES having the same stent platform and drug, and differing ...
Kim Sang Chul - - 2012
BACKGROUND: An adjunct to assist cardiopulmonary resuscitation (CPR) might improve the quality of CPR performance. STUDY OBJECTIVES: This study was conducted to evaluate whether a simple audio-visual prompt device improves CPR performance by emergency medical technicians (EMTs). METHODS: From June 2008 to October 2008, 55 EMTs (39 men, mean age 34.9±4.8 ...
Dilber Erhan E Department of Prosthodontics, Faculty of Dentistry, Selcuk University, Konya, Turkey. - - 2012
The aim of this study was to evaluate the effects of different surface treatments on the surface roughness of lithium disilicate-based core (IPS Empress 2, shade 210, Ivoclar Vivadent, Schaan, Liechtenstein) and feldspathic ceramics (Vita VM9, VITA Zahnfabrik H. Rauter GmbH & Co. KG, Bad Säckingen, Germany). Er:YAG laser irradiation ...
Magnuson J Scott - - 2012
BACKGROUND: We evaluated factors associated with long-term dependence on percutaneous endoscopic gastrostomy (PEG) tubes. METHODS: One hundred fifty-four patients receiving treatment at the University of Alabama at Birmingham between 2002 and 2004 who underwent PEG tube placement were identified through retrospective review of medical records. Using binary logistic regression, we ...
Cho Soo Ick - - 2012
BACKGROUND: Fractional technology overcomes the problems of ablative lasers, such as inaccurate depth control and damage to the epidermis. Minimally invasive fractional radiofrequency microneedle devices allow for more-selective heating of the dermis. OBJECTIVE: To evaluate the clinical efficacy of fractional radiofrequency microneedle (ERM) treatment in acne scars and large facial ...
Ritz Thomas - - 2012
BACKGROUND: Individuals with asthma have been shown to respond to unpleasant stimuli with bronchoconstriction, but little is known about the time course of responding during sustained emotional stimulation and whether it varies with patients' experience. OBJECTIVE: To examine the time course of oscillatory resistance (R(os)) during emotionally evocative films in ...
Byrne Robert A - - 2012
Evaluation of: Stefanini GG, Kalesan B, Serruys PW et al. Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 4 year follow-up of a randomised non-inferiority trial. Lancet 378(9807), 1940-1948 (2011). Biodegradable polymer-coated drug-eluting stents (DESs) represent an attractive ...
Stefanini Giulio G - - 2012
AimsThe efficacy of durable polymer drug-eluting stents (DES) is delivered at the expense of delayed healing of the stented vessel. Biodegradable polymer DES aim to avoid this shortcoming and may potentially improve long-term clinical outcomes, with benefit expected to accrue over time. We sought to compare long-term outcomes in patients ...
Zhang Lan - - 2012
Background: More widespread use of drug-eluting stents (DES) to treat coronary heart disease (CHD) has recently generated more attention to thrombosis, which was relative to the polymer. Polymer-free and biodegradable polymer-based stents are more frequently studied, but their efficacy on preventing detrimental clinical events is unclear. Methods and Results: To ...
Broadhurst M K - - 2012
This study assessed the mortality of 157 snapper Pagrus auratus (9-29 cm, total length, L(T) ) after being conventionally angled and then released into cages (along with 48 controls) for 4 days off south-eastern Australia. Fatalities were restricted to 12 angled fish (7·6%) and mostly attributed to the ingestion of ...
Cho Byung Chae - - 2012
The synchondrosis between the sixth and seventh costal cartilage is usually used for the base frame in autogenous ear reconstruction. If the synchondrosis is loose, a variety of modifications can be devised. This report introduces new methods for these problems. In cases of incomplete synchondrosis, only the surface of the ...
Shimoda Masayuki M Baylor University Medical Center at Dallas, Dallas, TX - - 2012
A delivery of collagenase at the islet-exocrine interface is crucial for successful human islet isolation. In this study, we investigated how the ductal preservation method at the procurement site affected collagenase distribution. At first, we analyzed human islet isolation data among groups using Serva collagenase with or without ductal injection ...
Taylor Eric - - 2012
Introduction: The metallic ureteral stent was first developed for patients with ureteral obstruction related to malignant disease, but it can be used in all patients requiring chronic indwelling ureteral stents, including those with benign disease. The traditional method of polymer stent management often requires multiple exchanges per year depending upon ...
Souza Jeff - - 2012
Interim leaders can set the stage for long-term success.
Weiss Hans-Rudolf - - 2012
The use of soft braces to treat scoliosis has been described by Fischer as early as 1876. With the help of elastic straps, as the authors suggested, a corrective movement for individual curve patterns should be maintained in order to inhibit curve progression. Today this concept has been revived besides ...
Matsumura Goki - - 2012
We have developed a new biodegradable scaffold that does not require any cell seeding to create an in-situ tissue-engineering vasculature (iTEV). Animal experiments were conducted to test its characteristics and long-term efficacy. An 8-mm tubular biodegradable scaffold, consisting of polyglycolide knitted fibers and an L-lactide and ε-caprolactone copolymer sponge with ...
Trairatvorakul Chutima - - 2011
International Journal of Paediatric Dentistry 2011 Background.  Considering formocresol's toxicity, Ca(OH)(2) partial pulpotomy (PP) was studied as a treatment alternative. Aim.  To compare success rates of Ca(OH)(2) PP versus formocresol pulpotomy (FP) treatment of pulpally exposed lower primary molars. Design.  A total of 84 lower primary molars, which met study ...
Aldosary Barrak M - - 2011
Introduction. Selenium is an essential trace element, but can be toxic in excess. In May 2008, US FDA reported 201 individuals with adverse reactions to liquid nutritional supplements containing excess selenium and chromium resulting in the largest epidemic of selenosis in the history of the United States. Objective. To describe ...
Alvaro-Villegas J C - - 2011
Background: chronic radiation proctopathy (CRP) is associated with recurrent rectal bleeding and transfusional requirements. Argon plasma coagulation (APC) and hyperbaric oxygen therapy (HOT) have been shown to be effective in the control of CRP. No prospective comparisons have been reported between these treatments.Aim: the aim was to evaluate the effectiveness, ...
Flores G L - - 2011
Objective: The purpose of this study was to examine the efficacy and toxicity of treating small arteriovenous malformations (AVMs) (≤3 cm in diameter) with a median marginal applied dose of 14 Gy. Methods: Two hundred and thirteen patients diagnosed with AVMs were treated between January 1991 and December 2005. Seventy-three ...
Lucas William C - - 2011
In bioretention systems used for stormwater treatment, runoff interception improves with increased infiltration rates. However, nitrogen retention improves with increased retention time or decreasing infiltration rates. These contrasting responses were analyzed in 240-L experimental mesocosms using a variety of media treatments. The mesocosms were vegetated, except for one barren control. ...
Heravian Javad - - 2011
Ocular toxicity from hydroxychloroquine (HCQ) is rare, but its potential permanence and severity makes it imperative to employ measures and screening protocols to minimize its occurrence. This study was performed to assess the usefulness of color vision, photo stress recovery time (PSRT), and visual evoked potentials (VEP) in early detection ...
Vanselow B A - - 2011
Seven common marmoset monkeys (Callithrix jacchus) from a laboratory colony of 17 died over a period of eight months. Death of six of these monkeys was attributed to kidney failure from an oxalate-induced nephropathy. The epidemiology of this outbreak suggested an exogenous source and there was strong evidence that the ...
Holmes W J M - - 2011
Infantile Digital Fibromatosis (IDF) is a benign, often asymptomatic nodular proliferation of fibrous tissue occurring almost exclusively on the extremities. Conventional treatment has included radical surgery but this is associated with a high level of recurrence. Whilst some authors suggest a strictly conservative approach, this is unacceptable when lesions become ...
Chowta Nithyananda K - - 2011
Toxic epidermal necrolysis (TEN), also known as Lyell's syndrome, is a widespread life-threatening mucocutaneous disease where there is extensive detachment of the skin and mucous membrane. Many factors involved in the etiology of TEN including adverse drug reactions. Here we are reporting a case of toxic epidermal necrolysis in an ...
Hwang Yih-Shiou - - 2011
To evaluate enteric-coated mycophenolate sodium (EC-MPS) as a corticosteroid-sparing agent in the treatment of autoimmune scleritis. A retrospective, interventional, noncomparative review of EC-MPS use in patients with autoimmune scleritis. Seven eyes of 5 patients (all female; median age: 47 years, range: 20-55 years) with inflammatory scleral disease were treated with ...
Axelsson Sara - - 2011
To evaluate if treatment start and age are related to the outcome in Bell's palsy patients treated with prednisolone. Prospective, randomized, double-blind, placebo-controlled, multicenter trial. Sixteen otorhinolaryngologic centers in Sweden and 1 in Finland. Data were collected from the Scandinavian Bell's palsy study. A total of 829 patients were treated ...
Rejchrt Stanislav - - 2011
Bio-degradable stents are be made of different synthetic polymers (like polylactide or polyglycolide) or their co-polymers (polydioxanone). They can be used for treating benign stenoses of the small and large intestine, particularly in Crohn's disease. Endoscopic introduction of bio-degradable stents into small and large intestinal stenoses is feasible and relatively ...
Onaran Zafer - - 2011
Aim. To describe a case of toxic epidermal necrolysis (TEN) with ocular involvement treated with topical ophthalmic cyclosporine. Case Presentation. A 20-year-old woman developed TEN following administration of carbamazepine that was prescribed for epilepsy. Ophthalmic examination revealed bilateral pseudomembranous conjunctivitis. She was hospitalized in the intensive care unit and treated ...
Puéchal Xavier - - 2011
There is an unmet need for the treatment of adult Still's disease (ASD), the pathogenesis of which may involve interleukin-6 (IL-6). We report the first series of patients with ASD treated with tocilizumab (TCZ), a humanized anti-IL-6 receptor antibody. All ASD patients treated with TCZ in France between July 2006 ...
Rajaratnam R - - 2010
Toxic epidermal necrolysis (TEN) is a rare, severe blistering disease. Outcome data in British patients is limited to case reports or small series. To characterize the aetiology, clinical features, complications and outcome in TEN, and to evaluate the effect of treatments including intravenous immunoglobulin (IVIg). This was a retrospective study ...
Beksac Meral - - 2011
The combination of melphalan-prednisone-thalidomide (MPT) has been investigated in several clinical studies that differed significantly with regard to patient characteristics and treatment schedules. This prospective trial differs from previous melphalan-prednisone (MP) vs. MPT trials by treatment dosing, duration, routine anticoagulation, and permission for a crossover. Newly diagnosed patients with multiple ...
Domingo Christian - - 2011
Several studies have demonstrated the beneficial effects of omalizumab in asthma patients. Here we describe the drug's tolerance and oral corticosteroid sparing capacity in a long-term observational study. Thirty-two patients aged ≥18 years with obstructive airway disease and FEV(1) reversibility ≥12% and 200  mL, with an oral steroid requirement ≥7.5  ...
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