Search Results
Results 401 - 450 of 1805
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Nava S - - 2009
A study was carried out to determine the efficacy of topical eprinomectin against nymphal infestation of Otobius megnini in cattle, where a group of 14 individuals were treated with a dose of 0.5mg/per kg of body weight applied on the dorsal midline, and a group of 14 individuals remained as ...
Saruya Kanako - - 2009
Plasmocytosis circumorificialis is a benign chronic inflammatory disease, which causes erythema, erosions, ulcers, nodules and related changes in and around the openings of the human body, and is histopathologically characterized by dense infiltration of the dermis by plasma cells. We recently encountered a 49-year-old man in whom this disease affected ...
Katsarou A - - 2009
BACKGROUND: Tacrolimus inhibits T-lymphocyte activation and dermal Langerhans' cells, without the side-effects of corticosteroids. The safety profile of tacrolimus makes it a promising therapeutic option for dermatitis affecting the delicate periorbital skin. OBJECTIVE: To access the efficacy and tolerability of tacrolimus ointment 0.1% in the treatment of allergic contact eyelid ...
Radakovic Sonja - - 2009
BACKGROUND: Photochemotherapy using psoralen and ultraviolet A light (PUVA) is a highly effective treatment option for patients with severe psoriasis. Maintenance treatment has been advocated to provide for sustained remission. However, only a few studies have been conducted to assess the efficacy of maintenance treatment and these have provided inconsistent ...
Novaković Ljubomir - - 2009
BACKGROUND: Phototherapy is generally effective for psoriasis but individual responsiveness and optimal treatment duration for disease clearance are unpredictable. However, easy, rapid and non-invasive plaque assessment by spectrophotometric intracutaneous analysis (SIAscopy), a novel multispectral skin imaging technique, may now make prediction feasible. OBJECTIVES: The early prediction of psoriatic plaque clearance ...
James P J - - 2009
OBJECTIVE: To test strategies for the application of dicyclanil and mid-season crutching to maximise protection of unmulesed sheep against breech strike. PROCEDURE: Three hundred and eighty unmulesed Merino weaners were randomly allocated to four groups either left untreated or treated by different strategies with 50 g/L dicyclanil. Treatments included breech ...
Zawislak Agnieszka A - - 2009
This study evaluated the clinical and histopathological responses of vulval lichen sclerosus (LS) and squamous hyperplasia (SH) to photodynamic therapy (PDT). A novel bioadhesive patch containing aminolevulinic acid (ALA) at a dose of (38 mg/cm(2)) was used to treat 10 patients before irradiation with light of 630 nm. Clinical, histopathological ...
Tzaneva Stanislava - - 2009
BACKGROUND: Both oral and bath PUVA with 8-methoxypsoralen (8-MOP) have been shown to be effective in the treatment of chronic palmoplantar eczema. However, most studies were retrospective and did not include longer follow-up periods. AIM: To compare the therapeutic efficacy, tolerability and duration of remission after oral vs. bath PUVA ...
Elsaie Mohamed L - - 2009
BACKGROUND: Botanical extracts and preparations have been used in different pathological conditions with success. An important group of phytochemical phenolic compounds are the catechins found in green tea. Acne is a widely occurring inflammatory condition that is estimated to affect 40 to 50 million Americans. Finding an effective, safe, cost-effective ...
Khazai Natasha B - - 2009
BACKGROUND: The optimal treatment for correcting or preventing vitamin D insufficiency in cystic fibrosis (CF) patients has not been established. OBJECTIVE: The aim of the study was to assess the relative efficacy of three modes of vitamin D therapy: cholecalciferol (D3), ergocalciferol (D2), and UV light in raising or maintaining ...
Hald M - - 2009
BACKGROUND: Hand eczema (HE) is a frequent, long-lasting disease with both personal and societal repercussions. Consequently, more information is needed on factors that maintain symptoms. OBJECTIVES: In this study, patients with HE were followed for 6 months from the first visit to a dermatologist to identify factors associated with severe ...
Tiplica G-S - - 2009
Treatment in psoriasis vulgaris continues to unmet needs in terms of efficacy, quality of life and costs. Patients with moderate forms of psoriasis are using topical corticosteroids as first-line therapy and patients with severe forms also use this therapy. Optimization of this treatment is made by the use of combination ...
Kotimäki J - - 2009
BACKGROUND: Photodynamic therapy (PDT; i.e. selective destroying of malignant cells by exposing them to red light after photosensitization) has been increasingly used for non-melanoma skin cancers. Due to excellent cosmetic and functional results, especially in difficult-to-treat areas, it may offer a comprehensive alternative to previous treatment modalities. OBJECTIVE: A series ...
Fernández-Guarino M - - 2009
BACKGROUND: Nail psoriasis is often refractory to traditional treatments, and patients with nail psoriasis usually demand a therapeutic option. Both photodynamic therapy (PDT) and pulse dye laser (PDL) have proved effective for plaque-type psoriasis, but they have not been evaluated in nail psoriasis. On the other hand, delta-aminolaevulinic acic has ...
Puccioni Marco - - 2009
PURPOSE: To evaluate retrospectively the long-term results of methyl aminolevulinate photodynamic therapy for the treatment of eyelid basal cell carcinoma. METHODS: Sixteen consecutive patients with eyelid basal cell carcinoma were treated with methyl aminolevulinate photodynamic therapy between January 2002 and April 2003. Selection criteria were tumors located at least 3 ...
Kishan Kumar Y Hari - - 2009
BACKGROUND: Very few studies have been performed to evaluate the efficacy and safety of narrow-band ultraviolet B (NBUVB) therapy in Indian patients with vitiligo and are of small sample size. Aims: The purpose of this study is to know the efficacy and safety of NBUVB in 150 vitiligo patients of ...
Tosti Antonella - - 2009
OBJECTIVE: To evaluate the therapeutic efficacy of acitretin in patients with isolated nail psoriasis. DESIGN: Open study involving 36 patients with moderate to severe nail psoriasis treated with acitretin. SETTING: University-based outpatient dermatology clinic specializing in nail diseases. PATIENTS: A total of 27 men and 9 women (mean age, 41 ...
Ko H-C - - 2009
Used as individual agents, topical antibiotics and benzoyl peroxide are known to be effective in treatment of acne. Clindamycin phosphate 1% with benzoyl peroxide 5% (CDP/BPO) is a new combination gel, made by rationale, in that combination drug is more effective than either ingredients used alone. Adapalene 0.1% (ADA) is ...
Kalyoncu Umut - - 2009
OBJECTIVE: The objective of the present study was to assess the frequency of self-reported psoriasis in a hip osteoarthritis (OA) cohort, and a secondary objective was to assess the course of hip OA with psoriasis. METHODS: ECHODIAH was a 3-year, randomised double-blind controlled trial evaluating diacerein vs. placebo in hip ...
Nakano A - - 2009
BACKGROUND/PURPOSE: Topical 5-aminolevulinic acid (ALA)-based photodynamic therapy (PDT) is effective for actinic keratosis (AK); few studies have examined Oriental patients. The aim of this study is to assess the efficacy of PDT for the treatment of Japanese AK patients classified by lesion size and histological severity. METHODS: Thirty patients with ...
Ghali Fred - - 2009
Many innovations in acne therapy have evolved since the discovery in 1949 that vitamin A derivatives affected epidermal proliferation. Approval of topical tretinoin solution in 1971 was followed by modifications in the formulation to improve tolerability and provide flexibility in dosing. Identification of retinoid receptors led to research that resulted ...
Dreno B - - 2009
BACKGROUND: Topical retinoids have been successfully used in the treatment of acne vulgaris but may induce irritation when used twice daily. The association of retinaldehyde (RAL) with glycolic acid (GA) have complementary activities, which could be of interest for adult women with acne because of a better tolerance/efficacy ratio. The ...
Lerche Catharina M - - 2009
Pimecrolimus and tacrolimus are topical calcineurin inhibitors developed specifically for the treatment of atopic eczema. Experience with long-term use of topical calcineurin inhibitors is limited and the risk of rare but serious adverse events remains a concern. We have previously demonstrated the absence of carcinogenic effect of tacrolimus alone and ...
Rosina Paolo - - 2009
BACKGROUND/PURPOSE: Videocapillaroscopy (VCP) can be used to explore microcirculatory modifications in skin diseases. Psoriasis presents a specifically altered capillaroscopic pattern with 'bushy' capillaries and a disarranged microangioarchitecture. The aim of the present study is to compare the clinical and capillaroscopic modifications of a psoriatic target lesion during topical therapy. METHODS: ...
Olejek Anita - - 2009
BACKGROUND: Vulvar lichen sclerosus (LS) affects primarily women at postmenopausal age and its background remains unknown. One of the treatment modalities is photodynamic therapy (PDT). The aim was to investigate the efficacy of PDT in women with LS and the analysis of protein expression before and after PDT. MATERIAL AND ...
Campione Elena - - 2009
Patients who respond only partially to etanercept may require additional treatments that act synergistically to improve their therapeutic response while at the same time reducing the dose required and the risk of side-effects. The aim of this study was to evaluate the effecti veness of topical calcipotriol in etanercept partial ...
Ghysel Christophe - - 2009
OBJECTIVES: To evaluate the long-term efficacy of topical application of a potent corticoid cream and skin stretching in the treatment of unretractable foreskin, pinpoint phimosis, balanopreputial adhesions and lichen sclerosus in prepubertal boys. METHODS: 462 prepubertal boys (mean age 4.7 years) with unretractable foreskin applied a topical potent corticoid cream ...
Shaffelburg Michael - - 2009
BACKGROUND: Field-directed therapies for actinic keratosis include photodynamic therapy and imiquimod. OBJECTIVES: The author designed a randomized, vehicle-controlled, split-face study to explore the safety and efficacy of photodynamic therapy followed by imiquimod. METHODS: The entire face of adults with > or =10 facial actinic keratoses were treated with photodynamic therapy ...
Ersoy-Evans Sibel - - 2009
BACKGROUND: Current knowledge about the efficacy of narrowband UVB therapy for the treatment of pityriasis lichenoides is limited. Objective: The aim of this study was to investigate the efficacy of narrowband UVB therapy for the treatment of pityriasis lichenoides chronica (PLC). METHODS: Data were retrospectively collected following a review of ...
Zane Cristina - - 2009
BACKGROUND: Efalizumab, albeit highly efficient in psoriasis treatment, displays a slower rate of clearance when compared to anti-tumor-necrosis-factor-alpha drugs. It has been suggested that a combination of treatments might accelerate efalizumab response. OBJECTIVE: To determine whether the combination of narrow-band ultraviolet B (NB-UVB) phototherapy and efalizumab could improve the therapeutic ...
Stotland Mira - - 2009
Dapsone, a synthetic sulfone that has been available for over 60 years, has been used to treat a myriad of cutaneous disorders. Prior to the general acceptance of isotretinoin, oral dapsone had been reported to be effective in the treatment of nodulocystic acne. However, the potential for systemic toxicity prevented ...
Rigopoulos D - - 2009
BACKGROUND: Treatment of nail psoriasis remains a challenge. OBJECTIVE: To evaluate the efficacy of a two-compound product of calcipotriol plus betamethasone dipropionate ointment on nail psoriasis in an open-label study. METHODS: Twenty-five psoriatic patients with nail involvement and mild cutaneous psoriasis were instructed to apply a calcipotriol-betamethasone valerate ointment formulation ...
Hon Kam-Lun E - - 2009
INTRODUCTION: Recalcitrant childhood atopic dermatitis (AD) causes significant morbidity and may necessitate systemic treatment with immunomodulating agents such as azathioprine. We reviewed the clinical and biochemical effects of this agent in children and adolescents receiving this treatment between November 2005 and December 2007. METHODS: The clinical efficacy of azathioprine, and ...
Ventura F - - 2009
Lentigo maligna (LM) is the in situ phase of lentigo maligna melanoma, which may progress to invasive melanoma if left untreated. It mainly occurs on sun-exposed areas of elderly patients. The lesions can be large and conventional surgery can be difficult, particularly on the face. Recent reports indicate that topical ...
Cicek Demet - - 2009
Background: Seborrhoeic dermatitis is a common, chronic, papulosquamous dermatosis. Treatment of seborrhoeic dermatitis includes topical treatments such as corticosteroids, antifungals, metronidazole and pimecrolimus. Objective: This study aimed to compare and contrast the efficacy and tolerability of pimecrolimus cream 1%, methylprednisolone aceponate 0.1% cream and metronidazole 0.75% gel topical treatments in ...
Amelotti Ivana - - 2009
Triatoma infestans is the main vector of Chagas disease in the Gran Chaco region of South America. The traditional spraying technique used for the application of pyrethroid insecticides has shown low efficiency in the elimination of the vector species populations occupying peridomestic structures of rural houses in the endemic area ...
Fabbrocini G - - 2009
BACKGROUND: Photodynamic therapy (PDT) with aminolevulinic acid (ALA) has been shown to be an effective treatment for acne. However, the effect of ALA PDT on comedo formation has never been objectively evaluated. Cyanoacrylate follicular biopsy (CFB), a noninvasive procedure, has been proposed as the most reliable tool for studying follicular ...
Butler Glenn - - 2009
Psoriasis is an inflammatory and immunological cutaneous disease. The high morbidity in patients with psoriasis results from severe clinical manifestations and/or adverse effects of treatment. The Undersea and Hyperbaric Medical Society and Federal Medicare and Medicaid Services have approved the use of hyperbaric oxygen (HBO(2)) for more than 15 indications, ...
Alsamarai Abdulghani Mohamad - - 2009
BACKGROUND: The burden of scabies is highest in tropical countries, but recent data from Iraq are scanty. OBJECTIVE: To estimate the frequency of scabies in patients of a dermatology clinic in central Iraq. METHODOLOGY: The study was conducted in Tikrit (Iraq), between May 2007 and February 2008. A total of ...
Weber H Oliver - - 2009
While localized variants of granuloma annulare are typically self-limited, disseminated granuloma annulare tends to be chronic and often therapy-resistant. Treatment with fumaric acid esters is effective for severe forms of psoriasis. Disseminated granuloma annulare has also been reported to respond to fumaric acid esters. We treated 8 patients (mean age ...
Ständer Sonja - - 2009
Chronic pruritus is difficult to treat and requires the evaluation of new therapeutic modalities. We initiated an open-labelled, two-arm prospective, proof-of-concept study applying two selective serotonin re-uptake inhibitors on a long-term basis. Paroxetine and fluvoxamine were tested in a total of 72 pruritic patients (27 men, 45 women, age range ...
Kamili Qurat Ul Ain - - 2009
Topical therapy forms the cornerstone in the management of psoriasis. Of significant value as monotherapy in mild to moderate psoriasis, it is used predominantly as adjunctive therapy in moderate and severe forms of the disease. Over the past decade, topical treatment of psoriasis has evolved from the age-old applications of ...
Xu Ai-E - - 2009
BACKGROUND: Vitiligo is an acquired, pigmentary skin disorder which is disfiguring and difficult to treat. Phototherapy and application of topical corticosteroids are most commonly prescribed. However, these therapies are often not effective and use of corticosteroids on the face may lead to cutaneous atrophy, telangiectasia, and ocular complications. OBJECTIVE: We ...
Kartal Durmazlar Selda Pelinxs - - 2009
BACKGROUND: Topical cantharidin has been reported to be effective and safe in the treatment of cutaneous warts but it has not previously been used for the treatment of facial flat warts. OBJECTIVE: To evaluate the efficacy and safety of topical cantharidin in the treatment of recalcitrant facial flat warts. METHODS: ...
Cicek Demet - - 2009
BACKGROUND: Seborrhoeic dermatitis is a common, chronic, papulosquamous dermatosis. Treatment of seborrhoeic dermatitis includes topical treatments such as corticosteroids, antifungals, metronidazole and pimecrolimus. OBJECTIVE: This study aimed to compare and contrast the efficacy and tolerability of pimecrolimus cream 1%, methylprednisolone aceponate 0.1% cream and metronidazole 0.75% gel topical treatments in ...
Cervelli Valerio - - 2009
The aim of our study was to analyze the results obtained with the ReCell system for surgical treatment of stable vitiligo. At Department of Plastic and Reconstructive surgery, University of Tor Vergata in Rome, we treated 15 patients with stable vitiligo during a 2-year period. The stability of vitiligo lesions ...
Kop Else N - - 2009
Efalizumab is therapeutically effective in moderate to severe plaque psoriasis. Rebound after discontinuing therapy affects approximately 14% of patients, while erythroderma occurs in less than 1% of the treated population. In this case report, we describe two non-responding patients with severe plaque psoriasis who developed erythroderma after treatment was ceased. ...
Kang Min Ju - - 2009
Lichen amyloidosis (LA) is a chronic, severely pruritic skin disease characterized by deposition of amyloid in the skin with no visceral involvement. Current treatments of LA are unsatisfactory, with high relapse rates, complications, and treatment failures. A 31-year-old woman with a history of refractory atopic dermatitis (AD) presented with pruritic, ...
Vena G A - - 2009
There is much evidence to show the efficacy of adalimumab, a human monoclonal antibody targeting tumour necrosis factor-alpha, in the treatment of plaque psoriasis. In this open-label experience, 147 high-need patients suffering from plaque psoriasis, with a mean Psoriasis Area and Severity Index (PASI) of 18.8, and concomitant psoriatic arthritis ...
Majid Imran - - 2009
Childhood vitiligo is always a challenge to treat, especially when the disease is progressing rapidly in such a patient. Oral minipulse with betamethasone has been tried in childhood vitiligo and also in some other immune mediated skin disorders with good results. The aim of the present study was to see ...
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