Search Results
Results 1 - 50 of 1256
1 2 3 4 5 6 7 8 9 10 >
de Sousa Eduardo Branco EB Research Division, National Institute of Traumatology and Orthopaedics, Avenida Brasil, 500 - 5° Andar, Rio de Janeiro, RJ, 20940-070, Brazil, - - 2014
Osteochondral defects may progress to osteoarthritis. Many attempts have been developed to overcome this issue, including osteochondral autografts and allografts. The goal of this study was to develop a new protocol for storage of human osteochondral allografts. Osteochondral plugs were randomly allocated in the following groups: control, immediate freezing up ...
Ang Marcus M Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore, Singapore, - - 2014
Age-related cataract is the opacification of the lens, which occurs as a result of denaturation of lens proteins. Age-related cataract remains the leading cause of blindness globally, except in the most developed countries. A key question is what is the best way of removing the lens, especially in lower income ...
Chang Liu L 1 State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University , Guangzhou, China - - 2014
Abstract Purpose: To compare the effects of topical nonsteroidal anti-inflammatory drugs on pupil dilation maintenance during phacoemulsification cataract surgery and quantify the relationships between pupil size change and nuclear hardness. Methods: This prospective randomized clinical observation study was single centered and double-masked. We studied 239 cases undergoing uneventful phacoemulsification cataract ...
Moussata Driffa D Gastroenterology Department, Lyon Sud Hospital, Pierre Benite, - - 2014
Patients with familial adenomatous polyposis (FAP) and severe (stage IV) duodenal polyposis are candidates for pancreaticoduodenectomy, which has high morbidity. Little information is available about the feasibility of therapeutic endoscopy for these patients. To evaluate the long-term efficiency and risks of endoscopic therapy. Retrospective study. A 2-referral center long-term cohort ...
Chang Dolly S DS Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, - - 2012
This is the protocol for a review and there is no abstract. The objectives are as follows: To compare the efficacy as well as harms of early lens extraction versus standard treatment in patients with acute primary angle closure.
Vardakas Konstantinos Z - - 2012
OBJECTIVES: To study the comparative mortality associated with carbapenems and alternative antibiotics for the treatment of patients with extended-spectrum β-lactamase (ESBL)-positive Enterobacteriaceae bacteraemia. METHODS: We searched systematically PubMed and Scopus databases for studies providing data for mortality among patients treated with carbapenems, β-lactam/β-lactamase inhibitor combinations (BL/BLIs) or non-BL/BLIs (mainly cephalosporins ...
Chan Kevin E - - 2012
Staphylococcus bacteremia is a common and life-threatening medical emergency, but it is treatable with appropriate antibiotic therapy. To identify opportunities that may reduce morbidity and mortality associated with S. aureus, we analyzed data from 293,094 chronic hemodialysis outpatients to characterize practices of antibiotic selection. In the study population, the overall ...
Karosi Tamás - - 2012
OBJECTIVES/HYPOTHESIS: Microbial biofilms have been implicated in the pathogenesis of chronic rhinosinusitis with nasal polyposis (CRSwNP). Although biofilms are characterized by an extremely high resistance against chemical and physical agents, low-frequency ultrasound (LFU) treatment has been suspected to be an efficient and safe method for biofilm disruption. STUDY DESIGN: Basic ...
Ueng Steve W N - - 2012
The objective of this study was to evaluate the antibacterial activities of joint fluids of patients undergoing total-knee arthroplasty (TKA). Thirty patients who were scheduled for primary cemented TKA were enrolled in the study. The patients were grouped on the basis of whether the cement was without antibiotic loading (control ...
Kim Sun Gui - - 2012
OBJECTIVE: The purpose of this study was to evaluate the effect of furanone as a quorum sensing inhibitor with an antibiotic agent on experimentally induced Pseudomonas aeruginosa biofilm formation in an in vitro model. MATERIALS AND METHODS: Bacterial cultures on agar plates and induction of biofilm formations were done in ...
Zhang Zhi-Chao - - 2012
Levofloxacin is a synthetic fluoroquinolone that is usually used to treat chronic bacterial prostatitis. We investigated the safety and efficacy of levofloxacin compared with ciprofloxacin for the treatment of chronic bacterial prostatitis in Chinese patients. This was a multicenter, open-label, randomized controlled non-inferiority trial. Four hundred and seventy-one patients with ...
Schroeder Kristopher M - - 2012
Femoral nerve catheter (FNC) insertion is commonly performed for postoperative analgesia following total knee arthroplasty (TKA). A wide range of rates has been reported relating to the bacterial colonization of catheters complicating FNC insertion. The BIOPATCH® is a chlorhexidine (CHG) impregnated patch designed to inhibit bacterial growth for days. The ...
Koh Seong Joon - - 2012
Background/Aims: The aim of this study was to investigate the incidence and risk factors of irritable bowel syndrome (IBS) in community subjects with culture-proven bacterial gastroenteritis. Methods: This was a prospective, community-based, cohort study, which followed patients with a recent history of culture-proven bacterial gastroenteritis. IBS was diagnosed with the ...
Digiorgio Megan J - - 2012
Objective. To develop a modified surveillance definition of central line-associated bloodstream infection (mCLABSI) specific for our population of patients with hematologic malignancies to better support ongoing improvement efforts at our hospital. Design. Retrospective cohort study. Patients. Hematologic malignancies population in a 1,200-bed tertiary care hospital on a 22-bed bone marrow transplant (BMT) unit ...
Lorenzo-Gómez M F - - 2013
Urinary tract infections (UTIs) are considered the most common bacterial infections, especially in women. The objective of this study was to evaluate the use of the sublingual bacterial vaccine Uromune® in order to prevent recurrent UTIs (RUTIs). This study was conceived as a multicenter observational study. The clinical history of ...
Wiens Matthew O - - 2012
Background: The effectiveness of traditional adherence measurements used in adolescent populations is difficult to assess. Antiretroviral (ARV) adherence research among adolescents living with HIV in resource-constrained countries is particularly challenging and little evidence is available. Objectives: The primary objective of this study was to determine the feasibility of a large-scale, ...
Pathengay Avinash - - 2012
A systematic review of 27 reports of endophthalmitis outbreaks following cataract surgery between 1985 and 2011 found the 2 most common causes associated with the outbreaks were contaminated solutions, 10 reports (37%), and contaminated phacoemulsification machines, 6 reports (22.2%). Other possible sources of contamination included ventilation systems, 3 (11.1%); defective ...
de La Blanchardière A - - 2012
PURPOSE: To determine the association of clinical outcomes with the adherence to Infectious Diseases Consultation (IDC) recommendations. METHODS: From March to August 2009, all patients hospitalized in our hospital, for whom an IDC was requested, were prospectively enrolled. The adherence to recommendations was ascertained after 72 h from the IDC. The ...
Steward Rachel - - 2012
BACKGROUND: Few studies have examined the action of combined oral contraceptives (COCs) on cervical mucus. We hypothesized that midcycle cervical mucus of women taking COCs is of poor quality when compared to their own midcycle mucus prior to initiating COCs. We sought to compare the effect upon quality and sperm ...
Albrich Werner C WC Medical University Department, Kantonsspital Aarau, Aarau, - - 2012
In controlled studies, procalcitonin (PCT) has safely and effectively reduced antibiotic drug use for lower respiratory tract infections (LRTIs). However, controlled trial data may not reflect real life. We performed an observational quality surveillance in 14 centers in Switzerland, France, and the United States. Consecutive adults with LRTI presenting to ...
Lin Mu-Chun - - 2012
BACKGROUND: Bacterial meningitis has long been a severe infectious disease in neonates, as well as a leading cause of adverse outcomes. We designed this study to know the factors for poor prognosis in neonatal bacterial meningitis. METHODS: We enrolled children aged less than 1 month who were admitted to Mackay ...
DeLeon Jesse J Center for Clinical Trials, LLC, Paramount, CA, - - 2012
Besifloxacin ophthalmic suspension 0.6% given thrice daily for 5 days is safe and effective in the treatment of patients with bacterial conjunctivitis. This study evaluated the safety and efficacy of besifloxacin ophthalmic suspension 0.6% administered twice daily for 3 days compared with vehicle in the treatment of bacterial conjunctivitis. This ...
Marcus S - - 2012
To determine if postpartum subclinical infection occurs in sows, a novel device was used to diagnose such bacterial contamination of the vagina. The device was based on the measurement of biogenic amines by ion mobility spectrometry (IMS). The device is portable and results are obtained within 1 min. Vaginal swabs ...
Krespi Yosef P - - 2012
OBJECTIVES: Methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant S aureus (MRSA) contribute to 25% of nosocomial infections, increasing complications, health care cost, and growing antibiotic resistance. Nasal decolonization (ND) can reduce the staphylococcal infection rate. A new method of laser therapy (LT) MRSA ND was tested. STUDY DESIGN: This is a ...
Kiwuwa-Muyingo S S School of Health Sciences, University of Tampere, Finland. - - 2012
To describe associations between different summaries of adherence in the first year on antiretroviral therapy (ART) and the subsequent risk of mortality, to identify patients at high risk because of early adherence behaviour. We previously described an approach where adherence behaviour at successive clinic visits during the first year on ...
Ryou Marvin - - 2012
BACKGROUND: NOTES via the gastrointestinal tract raises the specter of intra-peritoneal infection. Various anti-microbial techniques have been employed in animal and human survival studies, including saline lavage, intravenous and topical antibiotics, and povidone-iodine, although there is a paucity of data regarding their general effectiveness. AIM: To assess the effectiveness of ...
Mangell Peter - - 2012
Probiotics may exert beneficial effects in the gastrointestinal tract. This randomized trial investigated the effect of the probiotic Lactobacillus plantarum 299v on the intestinal load of potentially pathogenic bacteria, bacterial translocation, and cell proliferation in elective colon surgery. Seventy-five patients were randomized to pre- and postoperative oral intake of Lactobacillus ...
Taccetti Giovanni - - 2012
BACKGROUND: Pseudomonas aeruginosa chronic pulmonary infection is an unfavourable event in cystic fibrosis. Bacterial clearance is possible with an early antibiotic treatment upon pathogen isolation. Currently, no best practice exists for early treatment. The efficacy of two different regimens against initial P aeruginosa infection was assessed. METHODS: In a randomised, ...
Reinhardt Ch - - 2012
To cite this article: Int J Dent Hygiene DOI: 10.1111/j.1601-5037.2011.00543.x Reinhardt CH, Noack MJ, Wassmer G, Dumit J, Rolfs A, Klein K. Comparison of three forms of teaching - a prospective randomized pilot trial for the enhancement of adherence. Abstract:  Objective: Adherence of young adults to preventive programmes is low. The ...
Takci Sahin - - 2012
OBJECTIVES:: Storage of human milk by freezing has been recommended for long term storage. This study analyzed the bactericidal activity of human milk on Escherichia coli and Pseudomonas aeruginosa and determined the changes in bactericidal activity following freezing at -20°C and -80°C for one and three months. METHODS:: Forty eight ...
Dümichen M J - - 2012
BACKGROUND: A catheter lock solution containing 1.35% taurolidine and 4% citrate could potentially disrupt bacterial surface adherence and consecutive biofilm production due to the anti-adherence properties of taurolidine and the anticlotting and chelator activities of both compounds. AIM: To compare the impact on microbial catheter colonization and infectious complications of ...
Colombo Ana Paula V AP Department of Medical Microbiology, Institute of Microbiology of Federal University of Rio de Janeiro, Brazil. - - 2012
This study compares the changes to the subgingival microbiota of individuals with "refractory" periodontitis (RP) or treatable periodontitis (good responders [GR]) before and after periodontal therapy by using the Human Oral Microbe Identification Microarray (HOMIM) analysis. Individuals with chronic periodontitis were classified as RP (n = 17) based on mean ...
- - 2012
OBJECTIVE: Both nosocomial acquired meningitis (NAM) as well as community acquired meningitis (CAM) were despite 70 years antibiotics and vaccination use still associated with unacceptably high mortality as well as psychological sequelae. Purpose of this study was to assess if differences in etiology and risk factors among bacterial meningitis acquired ...
- - 2012
OBJECTIVE: Mortality on cardiovascular disease among Roma ethnic is high than in overall population. In this study we investigated outcome and mortality on community acquired bacterial (CAM) meningitis in Roma ethnic minority. METHODS: We analysed and compared 16 cases bacterial meningitis occurring in Roma ethnic minority to all 554 bacterial ...
- - 2012
OBJECTIVE: One of the leading cause of bacterial neuroinfections worldwide is meningococcal meningitis (MM) and represents in many countries significant public health problem. The aim of this study was to overview outcome of meningococcal meningitis in Slovakia. METHODS: Risk factors such as underlying disease, cancer, diabetes alcoholism, surgery, age, previous ...
Mendez-Probst Carlos E - - 2012
Study Type - Therapy (RCT) Level of Evidence 1b What's known on the subject? and What does the study add? Infection, encrustation and ureteral-stent-related symptoms (USRS) including pain, urgency and frequency are all major problems associated with stent use. No current ureteral stent or exogenously applied therapy adequately deals with these ...
Carvalho Vladimir Cordeiro de - - 2012
Despite the growing interest in the study of Gram-negative bacilli (GNB) infections, very little information on osteomyelitis caused by GNB is available in the medical literature. To assess clinical and microbiological features of 101 cases of osteomyelitis caused by GNB alone, between January 2007 and January 2009, in a reference ...
Chanishvili Nina - - 2012
Felix d'Herelle proposed the use of bacteriophages for the therapy of human and animal bacterial infections at the beginning of the 20th century. This approach, however, was not widely accepted in the West. After the emergence of antibiotics in 1940s, phage research was diverted to a more fundamental level. At ...
Unemo M - - 2012
We describe the second case in Europe of verified treatment failure of pharyngeal gonorrhoea, caused by an internationally occurring multidrug-resistant gonococcal clone, with recommended first-line ceftriaxone 250 mg in Slovenia. This is of grave concern since ceftriaxone is last remaining option for empirical treatment. Increased awareness of ceftriaxone failures, more ...
Duggan Derek - - 2012
Objective. This study compared the leakage resistance of a New Sealer Prototype (NSP) with a traditional sealer (AH 26) in Resilon-filled roots subjected to a bacterial challenge. Study Design. 41 roots were instrumented to ISO size 50 apically. Group 1 (n = 20) contained Resilon and AH 26 sealer and ...
Cohen Jessica L - - 2012
Increasing affordability of artemisinin combination therapy (ACT) in the African retail sector could be critical to expanding access to effective malaria treatment, but must be balanced by efforts to protect the efficacy of these drugs. Previous research estimates ACT adherence rates among public sector patients, but adherence among retail sector ...
Yamanaka Wataru - - 2012
Supragingival plaque is permanently in contact with saliva. However, the extent to which the microbiota contributes to the salivary bacterial population remains unclear. We compared the compositional shift in the salivary bacterial population with that in supragingival plaque following periodontal therapy. Samples were collected from 19 patients with periodontitis before ...
Diec Jennie - - 2011
OBJECTIVES:: The aim of this study was to investigate the relationship between solution-induced corneal staining (SICS) and silicone hydrogel contact lens comfort and vision. METHODS:: A retrospective analysis of a series of open-label studies were conducted with 24 groups of approximately 40 participants, each wearing 1 of 6 silicone hydrogel ...
Candeloro Christina L - - 2012
Objective  The purpose of this study was to describe antimicrobial utilization, consumption, indications and microbial resistance in a medical-surgical-trauma intensive care unit (ICU) of a teaching hospital to identify potential targets for antimicrobial stewardship. Methods  This was a 30-day prospective observational study enrolling adults admitted to the ICU for at ...
Ohta Kiyohiko - - 2011
PURPOSE:: To determine the density of corneal stromal cells in wearers of soft contact lenses (SCLs) and rigid gas-permeable (RGP) contact lenses (CLs). METHODS:: The keratocyte density (KD) was measured at different depths of the stroma by confocal microscopy. In study 1, 32 wearers of rigid gas-permeable (RGP) lenses and ...
Wang Yilong - - 2011
BACKGROUND AND PURPOSE: Little is known about intravenous recombinant tissue plasminogen activator (rtPA) use in China. By accessing the Chinese National Stroke Registry (CNSR), the rate of intravenous rtPA use was reviewed. We specifically examined the issues of prehospital and in-emergency department delay and compared them with the published data ...
Abouheif Mohamed Mahmoud - - 2011
PURPOSE: The objective of this study was to determine the safe penetration depth of the FasT-Fix meniscal suture repair system during all-inside repair of the posterior part of the lateral meniscus. METHODS: Thirty-one knees from 17 embalmed and formalin-fixed cadavers (11 women, 6 men) were used. In each case, the ...
Kaushik Sushmita - - 2011
Purpose. To evaluate the role of ultrasound biomicroscopy (UBM) in predicting the long-term outcome of sub-Tenon needling revision of failed trabeculectomy blebs. Methods. Adult patients with a failed trabeculectomy bleb and unsatisfactory intraocular pressure (IOP) control were recruited. The aqueous flow under the partial thickness scleral flap was looked for ...
van den Berg A A - - 2011
Pencil-point spinal needles are popular for combined spinal-epidural analgesia because they cause less dural puncture headache than cutting-edge spinal needles. However many parturients move, grimace, vocalise or experience paraesthesia or dysaesthesia during dural puncture when performing 'needle through needle' combined spinal-epidural analgesia. We compared dural puncture responses induced by pencil-point ...
Hebard Simon - - 2011
Needle tip visualization is fundamental to the safety and efficacy of ultrasound-guided regional anesthesia (UGRA). It can be extremely challenging especially at steep insertion angles. We assessed whether an echogenic needle improved tip visibility during UGRA by anesthesiologists performing their normal in-plane technique. The visibility of the Pajunk Sonoplex (echogenic) ...
1 2 3 4 5 6 7 8 9 10 >