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Møller Morten Hylander - - 2010
Mortality and morbidity following perforated peptic ulcer (PPU) is substantial and probably related to the development of sepsis. During the last three decades a large number of preoperative prognostic factors in patients with PPU have been examined. The aim of this systematic review was to summarize available evidence on these ...
Golden David B K - - 2010
PURPOSE OF REVIEW: There have been a limited number of studies examining the outcome after discontinuing venom immunotherapy (VIT), all of which showed continued protection in the great majority of patients. Several different criteria have been proposed to select patients to stop treatment based on immunologic and clinical factors. Specific ...
Sharman M - - 2010
OBJECTIVES: To retrospectively review the first treatment response of dogs with mycotic rhinosinusitis to commonly utilised treatment techniques. METHODS: Medical records of dogs treated for mycotic rhinosinusitis were obtained retrospectively via a manual review of the clinical databases of six veterinary referral centres for the period of January 1998 to ...
Le Meur Yann - - 2010
The aims of this study were to determine (1) the individual tactics employed by elite modern pentathletes within each discipline of the new combined running-shooting event, and (2) the consequences of these strategies on overall performance. For 36 male pentathletes competing in a World Cup event, we measured running velocity, ...
Persson Jan - - 2010
PURPOSE OF REVIEW: Ketamine has been repeatedly reviewed in this journal but novel developments have occurred in the last few years prompting an update. Interesting recent publications will be highlighted against a background of established knowledge. RECENT FINDINGS: In the field of anesthesia, particularly in pediatrics, some contributions have been ...
Kramer Daniel G - - 2010
The purpose of this study was to quantitatively assess the relationship between therapy-induced changes in left ventricular (LV) remodeling and longer-term outcomes in patients with left ventricular dysfunction (LVD). Whether therapy-induced changes in left ventricular ejection fraction (LVEF), end-diastolic volume (EDV), and end-systolic volume (ESV) are predictors of mortality in ...
Naggara Olivier N - - 2010
PURPOSE: To report an updated, systematic review of medical literature from January 2003 to July 2008, on endovascular treatment (EVT) of intracranial unruptured aneurysms (UAs) (a) to assess the morbidity and case fatality rate of EVT of UAs, (b) to understand how bias can affect results, and (c) to estimate ...
- - 2010
Each year, the apportionment ballot is used to determine how many representatives each division and state, provincial, and territorial association will have on the Council of Representatives. The system is described in Article V, Sections 6 and 7, of the American Psychological Association (APA) Bylaws. Briefly, all APA fellows, members, ...
Paciullo Christopher A - - 2010
Septic shock is a major cause of morbidity and mortality in the intensive care unit, and effective therapies are limited. Methylene blue is a selective inhibitor of guanylate cyclase, a second messenger involved in nitric oxide-mediated vasodilation. The use of methylene blue in the treatment of septic shock has been ...
Lund Gregg - - 2010
Manual medicine--specifically osteopathic manipulative treatment (OMT)--is commonly used in treating patients aged 18 years or younger. However, no published reports have described characteristics of this patient population or the conditions for which OMT is used with these patients. To better counsel parents, train physicians and other healthcare providers, and prioritize ...
Domínguez Luis C - - 2011
Patients with nonspecific abdominal pain (NSAP) are frequently seen in emergency departments. Different studies have suggested that early laparoscopy (EL) could be an adequate tool to accelerate diagnosis and therapy. The aim of this study was to assess the effectiveness of EL in terms of diagnosis, persistence of NSAP, mortality, ...
Evans Jonathan - - 2011
To compare the efficacy of long-term primary nocturnal enuresis (PNE) treatment using desmopressin versus enuresis alarm. A 6-month randomized trial was performed with patients from 29 enuresis clinics: 251 patients ≥ 5 years in age with severe PNE (mean 5.5-5.6 wet nights/week) were randomized to desmopressin (0.2-0.4 mg daily) or ...
Alloussi S H - - 2011
To evaluate outcomes of desmopressin treatment in monosymptomatic enuresis (ME) and nonmonosymptomatic enuresis (NME). PubMed was searched for all studies investigating enuresis, up to July 2009, in which desmopressin was administered alone or combined with other treatments. Each study was graded according to its respective level of evidence. Altogether, 99 ...
Hammink Alice - - 2010
OBJECTIVE: Although there is growing evidence on the effectiveness of pre-notification and follow-up on response rates in patient surveys, no studies report the effectiveness of pre-notification in addition to follow-up. The aim of this study was to determine the effect of a pre-notification by mail on the response rate in ...
Steinberg Martin H - - 2010
A randomized, controlled clinical trial established the efficacy and safety of short-term use of hydroxyurea in adult sickle cell anemia. To examine the risks and benefits of long-term hydroxyurea usage, patients in this trial were followed for 17.5 years during which they could start or stop hydroxyurea. The purpose of ...
Fox Matthew P - - 2010
To estimate the proportion of all-cause adult patient attrition from antiretroviral therapy (ART) programs in service delivery settings in sub-Saharan Africa through 36 months on treatment. We identified cohorts within Ovid Medline, ISI Web of Knowledge, Cochrane Database of Systematic Reviews and four conference abstract archives. We summarized retention rates ...
Ng Vincent Y - - 2010
Recent case studies on the surgical treatment of femoroacetabular impingement (FAI) have introduced a large amount of clinical data. However, there has been no clear consensus on its efficacy. The current literature can be clarified to address 4 questions: (1) Does treatment for FAI succeed in improving symptoms? (2) In ...
Stip Emmanuel - - 2010
In clinical psychopharmacology, the optimal method of switching from treatment A to treatment B with regard to efficacy and tolerability is an important area of study. We investigated the effects on efficacy and tolerability of switching patients from conventional antipsychotics to ziprasidone. This was a 6-week open-label, randomized study of ...
Röllig Christoph - - 2010
We present an analysis of prognostic factors derived from a trial in patients with acute myeloid leukemia older than 60 years. The AML96 trial included 909 patients with a median age of 67 years (range, 61-87 years). Treatment included cytarabine-based induction therapy followed by 1 consolidation. The median follow-up time ...
Winterhalter Sibylle - - 2010
BACKGROUND: To evaluate the efficacy of suppressing a recurrence of Toxoplasma retinochoroiditis after treatment with atovaquone. METHODS: Retrospective, nonrandomized, clinical trial. Forty-one immunocompetent patients were treated for Toxoplasma retinochoroiditis with atovaquone between 1999 and 2006. The diagnosis was based on clinical signs alone. Atovaquone was given 750 mg two to ...
Hong Jong Won - - 2010
PURPOSE: The evaluation of microsurgical technique is often done in an attempt to enhance the skills of surgeons. However, it varies depending on the institution or supervisors. According to some of the research done so far, there are many institutes that enable surgeons to train themselves with enough time but ...
Joniau Steven - - 2010
BACKGROUND AND PURPOSE: The introduction of radiofrequency ablation (RFA) into other fields of surgery has fueled the interest to study its application in small renal masses (SRM). Some controversies remain, however, regarding its oncologic efficacy. We review technical factors and tissue characteristics that influence treatment success, discuss the evaluation of ...
McAlister Vivian - - 2010
BACKGROUND: Fluid excess may place patients undergoing surgery at risk for various complications. Hypertonic saline (HS) maintains intravascular volume with less intravenous fluid than isotonic salt (IS) solutions, but may increase serum sodium. OBJECTIVES: To determine the benefits and harms of HS versus IS solutions administered to patients undergoing surgery. ...
Jakobsen Lars - - 2010
The efficacy of primary percutaneous coronary intervention (PPCI) has been documented in several randomized-controlled trials. We sought to examine the clinical outcome after PPCI of real-world patients eligible and ineligible for inclusion in a randomized trial (DANAMI-2) and to compare it to the outcome of the DANAMI-2 population. We did ...
Songun Ilfet - - 2010
BACKGROUND: Historical data and recent studies show that standardised extended (D2) lymphadenectomy leads to better results than standardised limited (D1) lymphadenectomy. Based on these findings, the Dutch D1D2 trial, a nationwide prospectively randomised clinical trial, was undertaken to compare D2 with D1 lymphadenectomy in patients with resectable primary adenocarcinoma of ...
Routh Jonathan C - - 2010
OBJECTIVE: Published success rates of dextranomer/hyaluronic acid (Dx/HA) injection for pediatric vesicoureteral reflux (VUR) vary widely. Our objective of this study was to assess whether underlying patient or study factors could explain the heterogeneity in reported Dx/HA success rates. METHODS: We searched the Cochrane Controlled Trials Register and Medline, Embase, ...
Klocke P - - 2010
INTRODUCTION: Routine use of antibiotics to prevent mastitis in dairy cows is prohibited by organic farming regulations. Internal Teat Sealers have been proposed as an alternative. We compared two drying-off (DO) supporting measures (Internal Teat Sealer and Homeopathy) to an untreated control group to assess their protective effects against clinical ...
Buri L - - 2010
Inappropriateness of upper endoscopy (EGD) indication causes decreased diagnostic yield. Our aim of was to identify predictors of appropriateness rate for EGD among endoscopic centres. A post-hoc analysis of two multicentre cross-sectional studies, including 6270 and 8252 patients consecutively referred to EGD in 44 (group A) and 55 (group B) ...
Modi Avani C - - 2010
Although cross-sectional studies have demonstrated poor adherence to airway clearance therapy (ACT) for patients with cystic fibrosis (CF), no studies have identified longitudinal patterns of adherence. The objective was to characterize and identify predictors of ACT adherence trajectories for individuals with CF. Secondary data analyses were conducted for a randomized ...
Zimran Ari - - 2010
Enzyme replacement therapy is the standard of care for symptomatic Gaucher disease. Velaglucerase alfa is a human beta-glucocerebrosidase produced in a well-characterized human cell line. A 9-month phase 1/2 open-label, single-center trial and ongoing extension study were conducted to evaluate safety and efficacy of velaglucerase alfa. Twelve symptomatic adult type ...
Raebel Marsha A - - 2010
Background/Aims: Determination of hyperkalemia associated adverse outcomes incidence and risk assessment is complicated by lack of consistent hyperkalemia definitions across studies. Further, information about hyperkalemia from clinical trials, while reflecting the potential of renin-angiotensin-aldosterone system (RAAS) inhibitor treatment to increase serum potassium (K) concentration above a defined level, may not ...
Kim Hyung-Ho - - 2010
OBJECTIVE: The aim of this study was to evaluate the safety of this trial with respect to morbidity and mortality. SUMMARY BACKGROUND DATA: Laparoscopic-assisted distal gastrectomy (LADG) is rapidly gaining popularity. However, there is limited evidence regarding its oncologic safety. We therefore conducted a phase III multicenter, prospective, randomized study ...
Salomonsson Marcus - - 2010
This paper surveys the literature on group selection. I describe the early contributions and the group selection controversy. I also describe the main approaches to group selection in the recent literature; fixation, assortative group formation, and reproductive externalities.
Berggård Glenn - - 2010
Pedestrians slipping and falling is a major safety problem around the world, not least in countries with long winters such as Sweden. About 25000-30000 people need medical care every year for treatment of fall injuries in Sweden. Use of appropriate shoes and anti-slip devices are examples of individual measures that ...
Raphaël Mathilde - - 2010
PURPOSE: The European medicines agency (EMEA) has stated that the degree of pre-treatment could modify the patient's tolerance to new treatments in paediatric oncology. It is current practice to divide a phase I trial into two groups to identify the maximum tolerated dose (MTD) in each group separately. The aim ...
Leach Colin Wayne - - 2010
Reports an error in "Dejection at in-group defeat and schadenfreude toward second- and third-party out-groups" by Colin Wayne Leach and Russell Spears (Emotion, 2009[Oct], Vol 9[5], 659-665). In the article "Dejection at In-Group Defeat and Schadenfreude Toward Second- and Third-Party Out-Groups" by Colin Wayne Leach and Russell Spears (Emotion, 2009, ...
Schaad Urs B - - 2010
This study was conducted to assess the efficacy of OM-85 BV (Broncho-Vaxom) in the prevention of pediatric recurrent respiratory tract infections (RTIs). Available evidence suggests that defining recurrent RTIs as >or=3 infections per fall-winter semester is both medically and epidemiologically justified. Therefore, this criterion was chosen as a primary endpoint. ...
Huber Adam M - - 2010
To use juvenile dermatomyositis (DM) survey data and expert opinion to develop a small number of consensus treatment protocols, which reflect current initial treatment of moderately severe juvenile DM. A consensus meeting was held in Toronto, Ontario, Canada on December 1-2, 2007. Nominal group technique was used to achieve consensus ...
Wei Chen - - 2010
OBJECTIVE: This study aimed to systematically review the clinical efficacy of lipid emulsion containing fish oil in surgical patients. METHODS: Medline, SCI, Embase, Cochrane Library, and Chinese Biomedicine Database were searched for studies published before January 1, 2009 that were randomized controlled trials for postoperative patients. Parenteral nutrition with or ...
Svatek Robert S - - 2010
PURPOSE: Adverse event reporting is poorly classified and nonstandardized in the urological literature. We report adverse event data and associated risk factors using standardized reporting methods and Common Terminology Criteria for Adverse Events, version 3.0 to minimize interpretation bias and allow reliable comparisons with other populations. MATERIALS AND METHODS: We ...
Sagi Sashidhar V - - 2010
BACKGROUND AND AIM: Hepatorenal syndrome (HRS) is a serious complication of advanced liver disease and carries a poor prognosis. Recent trials have indicated that terlipressin may be effective in reversing HRS. Our aim was to evaluate the efficacy of terlipressin therapy in reversing type 1 HRS defined as a serum ...
Nienhuijs S W - - 2010
BACKGROUND: Haemorrhoidectomy is a frequently performed surgical procedure and associated with postprocedural pain. The use of the Ligasure may result in a decreased incidence of pain as coagulation with high frequency current and active feedback control over the power output results in minimal thermal spread and limited tissue charring. METHODS: ...
Stein Gregor - - 2010
Osteoarthritis (OA) is the most common degenerative arthropathy. Load-bearing joints such as knee and hip are more often affected than spine or hands. The prevalence of gonarthrosis is generally higher than that of coxarthrosis.Because no cure for OA exists, the main emphasis of therapy is analgesic treatment through either mobility ...
Mahto M - - 2010
To assess the effectiveness of 5% imiquimod cream (IQ) in the treatment of vulvar, penile and anal intraepithelial neoplasias (VIN, PIN and AIN), we searched Medline, Embase, PubMed and Cochrane Library databases. With regard to VIN there were two randomized controlled trials (RCTs), eight uncontrolled/cohort studies, nine case reports and ...
Doody Rachelle S - - 2010
Clinicians need to predict prognosis of Alzheimer's disease (AD), and researchers need models of progression to develop biomarkers and clinical trials designs. We tested a calculated initial progression rate to see whether it predicted performance on cognition, function and behavior over time, and to see whether it predicted survival. We ...
Andrijono Andri - - 2010
Around 15-28% of hydatidiform mole patients suffer from malignant degeneration following evacuation. Since retinoic acid can control cell proliferation and stimulate apoptosis, vitamin A could be used as a therapy for preventing such malignant transformation. The objective of this study was to demonstrate the use of vitamin A as a ...
Bausewein Claudia - - 2010
Breathlessness is common and distressing in advanced disease. This phase II study aimed to determine the use and acceptance of a hand-held fan (HHF) to relieve breathlessness, to test the effectiveness of the HHF and to evaluate the recruitment into the study. RCT embedded within a longitudinal study testing a ...
Clayton R N - - 2010
The causes of premature death in untreated Cushing's syndrome are vascular disease (myocardial infarction/stroke), uncontrolled diabetes mellitus and complications and infections. Long-term mortality outcome studies on pituitary-dependent Cushing's disease (CD) are limited to six studies in the English language literature. This paper reviews these studies on CD, other causes of ...
Naito Toru - - 2010
DATA SOURCES: Data was sought using Medline and the Cochrane Library, and relevant chapters from three major endodontic texts were consulted: Principles and Practice of Endodontics (4th Edn; editors; Torabinejad and Walton; 2008); Pathways of the Pulp (9th edition; editors, Cohen and Hargreaves; 2006), and Endodontics (6th edition; editors, Ingle, ...
Kliber Agnes - - 2010
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is the 4th leading cause of mortality worldwide. Long-acting bronchodilators are considered first line therapies for patients with COPD but their effects on mortality are not well known. We performed a comprehensive systematic review and meta-analysis to evaluate the effects of long-acting bronchodilators on ...
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