Search Results
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LORENZO PRENDINI
Two new flat rock scorpions, both endemic to South Africa, are described in the bicolor group of Hadogenes Kraepelin, 1894: H. polytrichobothrius n.sp.; H. soutpansbergensis n.sp. Both occupy discrete distributional ranges, allopatric with the other three species in the bicolor group: H. bicolor Purcell, 1899; H. longimanus Prendini, 2001; H. ...
Daniele Claudia - - 2006
Crataegus spp. (hawthorn) monopreparations are predominantly used for treating congestive heart failure. The effectiveness of hawthorn preparations (flowers with leaves; berries) is documented in a number of clinical studies, reviews and meta-analyses. The aim of this article is to assess the safety data of all available human studies on hawthorn ...
Matsuyama Yutaka - - 2006
BACKGROUND: In clinical trials, when comparing treatments in a subgroup of patients defined by an event that occurred after randomization is required, the standard estimator that adjusts for the post-treatment variable does not have a causal interpretation. PURPOSE: To address this problem, we formulate clinically relevant causal estimands using the ...
Liénard J-L - - 2006
PURPOSE: To provide empirical evidence on the impact of on-site initiation visits on the following outcomes: patient recruitment, quantity and quality of data submitted to the trial coordinating office, and patients' follow-up time. PATIENTS AND METHODS: This methodological study was performed as part of a randomized trial comparing two combination ...
Busanich Brian M - - 2006
What is the clinical evidence base for McKenzie therapy in management of back pain? Studies were identified using a computer-based literature search of 7 databases: MEDLINE, EMBASE, DARE, CINAHL, PEDro, the Cochrane Register of Clinical Trials (CENTRAL), and the Cochrane Database of Systematic Reviews. Search terms included McKenzie therapy, McKenzie ...
Macklis Roger M - - 2006
Iodine-131 (I-131) tositumomab (Bexxar; GlaxoSmithKline, Research Triangle Park, NC) is one of two recently approved radiolabeled antibodies directed against the CD20 surface antigen found on normal B cells and in more than 95% of B cell non-Hodgkin's lymphoma. The compound itself is formulated as an IgG2a immunoglobulin radiolabeled with the ...
Shikata Satoru - - 2006
To compare single- with two- layer intestinal anastomosis after intestinal resection: a meta-analysis of randomized controlled trials. Randomized controlled trials comparing single- with two-layer intestinal anastomosis were identified using a systematic search of Medline, Embase and the Cochrane Library Databases covering articles published from 1966 to 2004. Outcome of primary ...
Delaney Anthony - - 2006
Tracheostomy is one of the more commonly performed procedures in critically ill patients yet the optimal method of performing tracheostomies in this population remains to be established. The aim of this study was to systematically review and quantitatively synthesize all randomized clinical trials (RCTs), comparing elective percutaneous dilatational tracheostomy (PDT) ...
Hopkins C - - 2006
Acid reflux is a common problem, and is thought to occur in 4% to 10% of patients presenting to ENT clinics. A recent study of reflux and voice disorders suggests that up to 55% of patients with hoarseness (dysphonia) have laryngopharyngeal reflux. Anti-reflux therapy is often used empirically in treating ...
Bellamy N - - 2006
Osteoarthritis (OA) is a common joint disorder. In the knee, injections of corticosteroids into the joint (intraarticular (IA)) may relieve inflammation, and reduce pain and disability. To evaluate the efficacy and safety of IA corticosteroids in treatment of OA of the knee. We searched the Cochrane Central Register of Controlled ...
Gibbs S - - 2006
Viral warts are common and usually harmless but very troublesome. A very wide range of local treatments are used. To assess the effects of different local treatments for cutaneous, non-genital warts in healthy people. We searched the Cochrane Skin Group Specialised Register (March 2005), the Cochrane Central Register of Controlled ...
Paramothayan S - - 2006
Immunosuppressive and cytotoxic agents have been used as both an alternative to oral corticosteroids, and as a means of maintaining a low dose of steroids in the treatment of pulmonary sarcoidosis. To determine the efficacy of immunosuppressive and cytotoxic agents in the treatment of pulmonary sarcoidosis. CENTRAL, MEDLINE, EMBASE and ...
Cruz-Flores S - - 2006
Intracranial artery stenosis causes up to 10% of all ischaemic strokes. The rate of recurrent vascular ischaemic events is very high. Angioplasty with or without stent placement is a feasible procedure to dilate the vessel affected. However, its safety and efficacy have not been systematically studied. To determine the efficacy ...
Hutten B A - - 2006
Currently, the most frequently used secondary treatment for patients with venous thromboembolism is vitamin K antagonists targeted at an INR of 2.5 (range 2.0 to 3.0). However, based on the continuing risk of bleeding and uncertainty regarding the risk of recurrent venous thromboembolism, there is discussion on the proper duration ...
Marsland A M - - 2006
Chronic palmoplantar pustulosis (PPP) is a chronic inflammatory skin condition characterised by crops of sterile pustules (yellow pus spots) on the palms and soles which erupt repeatedly over months or years. The affected areas tend to become red and scaly; cracks may form and these are often painful. Many different ...
Dickersin K - - 2006
Nonarteritic ischemic optic neuropathy is characterized by sudden and painless loss of vision in the eye, accompanied by pallid swelling of the optic disc. No medical therapy has been proven effective in treating this condition. The objective of this review is to assess the safety and efficacy of surgery compared ...
Leontiadis G I - - 2006
Randomised controlled trials (RCTs) evaluating the clinical effect of proton pump inhibitors (PPIs) in peptic ulcer (PU) bleeding yield conflicting results. To evaluate the efficacy of PPIs in acute bleeding from PU using evidence from RCTs. We searched CENTRAL, The Cochrane Library (Issue 4, 2004), MEDLINE (1966 to November 2004), ...
Tisi P V - - 2006
Femoral pseudoaneurysms may complicate up to 8% of vascular interventional procedures. Small pseudoaneurysms can spontaneously clot, while others need definitive treatment. Surgery is considered the gold-standard treatment, although is not without risk in patients with severe cardiovascular disease. Less invasive treatment options, such as Duplex ultrasound-guided compression and percutaneous thrombin ...
Marjoribanks J - - 2006
Heavy menstrual bleeding (HMB) significantly impairs the quality of life of many otherwise healthy women. Perception of HMB is subjective and management usually depends upon what symptoms are acceptable to the individual. Medical treatment options include oral medication and a hormone-releasing intrauterine system (LNG-IUS). Surgical options include conservative surgery (uterine ...
Webster J - - 2006
Surgical site infections (SSIs) are wound infections that occur after invasive (surgical) procedures. Preoperative bathing or showering with an antiseptic skin wash product is a well-accepted procedure for reducing skin bacteria (microflora). It is less clear whether reducing skin microflora leads to a lower incidence of surgical site infection. To ...
Cook L A - - 2006
Currently, the two most common surgical techniques for approaching the vas during vasectomy are the incisional method and the no-scalpel technique. Whereas the conventional incisional technique involves the use of a scalpel to make one or two incisions, the no-scalpel technique uses a sharp-pointed, forceps-like instrument to puncture the skin. ...
Abou-Setta A M - - 2006
Various options exist for treating endometriosis, including ovarian suppression therapy, surgical treatment or a combination of these strategies. Surgical treatment of endometriosis sets out to remove visible areas of endometriosis and restore anatomy by division of adhesions. The aim of medical therapy is to inhibit growth of endometriotic implants by ...
Khan R J K - - 2006
Dislocation following hip replacement is associated with significant morbidity and functional cost. The cause is usually multifactorial. A variety of treatment options are available which can broadly be classified into operative and non-operative. To determine the best methods of treatment of recurrent dislocation following total hip replacement. The following databases ...
Moore M - - 2006
Croup (laryngotracheobronchitis) is a common cause of upper airway obstruction in children with a peak incidence of 60 per 1000 child years in those aged between one and two years. It is characterised by hoarseness, a barking cough, and inspiratory stridor. These symptoms are thought to occur as a result ...
Vimalachandra D - - 2006
Chronic kidney disease (CKD) is an uncommon but important condition. Growth retardation, one of the complications of CKD, is of concern to families. Recombinant human growth hormone (rhGH) treatment has been used to help short children with CKD attain a height more in keeping with their age group. However, there ...
Saab S - - 2006
Refractory ascites (ie, ascites that cannot be mobilized despite sodium restriction and diuretic treatment) occurs in 10 per cent of patients with cirrhosis. It is associated with substantial morbidity and mortality with a one-year survival rate of less than 50 per cent. Few therapeutic options currently exist for the management ...
Gurusamy K S - - 2006
Gallstones are present in about 10% to 15% of the adult western population. Between 1% and 4% become symptomatic in a year. Cholecystectomy for symptomatic gallstones is mainly performed after the acute cholecystitis episode settles because of the fear of higher morbidity and conversion from laparoscopic cholecystectomy to open cholecystectomy ...
Legg L A LA Glasgow Royal Infirmary, Academic Section of Geriatric Medicine, Glasgow, UK. - - 2006
Occupational therapy aims to help people reach their maximum level of function and independence in all aspects of daily life. To determine whether occupational therapy focused specifically on personal activities of daily living improves recovery for patients following stroke. We searched the Cochrane Stroke Group Trials Register (last searched January ...
Hatt S S International Centre for Eye Health, c/o Cochrane Eyes and Vision Group, London School of Hygiene & Tropical Medicine, Keppel Street, London, UK WC1E 7HT. - - 2006
Stimulus deprivation amblyopia (SDA) develops due to an obstruction to the clear passage of light, preventing clear formation of an image on the retina for example, cataract, ptosis (droopy eyelid). It is particularly severe and can be resistant to treatment and the visual prognosis is often poor. Stimulus deprivation amblyopia ...
Boodhwani Munir - - 2006
OBJECTIVE: Despite numerous studies comparing surgical versus percutaneous revascularization, the optimal treatment of patients with isolated left anterior descending (LAD) artery disease remains debated. We conducted a meta-analysis to study the early and mid-term outcomes following percutaneous and surgical treatment of isolated LAD disease. METHODS: Medline, EMBASE, and the Cochrane ...
Niël-Weise B S - - 2005
OBJECTIVE: To determine whether certain hair removal policies are better than others to prevent surgical-site infections in patients undergoing clean surgery. METHODS: Publications were retrieved by a systematic search of Medline, the Cochrane Library, and EMBASE up to February 2005. Additionally, the reference lists of all identified trials were examined. ...
Hern?ndez Adr?an V - - 2005
OBJECTIVE: Few randomized clinical trials (RCTs) in the field of traumatic brain injury (TBI) have shown a significant treatment benefit. We critically reviewed the use of two types of secondary analyses, covariate adjustment and subgroup analysis, which are common in TBI trials. METHODS: We performed a systematic review of therapeutic ...
Feusi Binja - - 2005
OBJECTIVE: The optimal surgical treatment for patients with posterior epistaxis and failed conservative therapy is unknown. Therefore we planned a systematic review studying all available publications assessing the effect on bleeding recurrence and postoperative complications of ligation of the internal maxillary artery or the sphenopalatine artery. METHODS: We searched the ...
Augustson Bradley M - - 2005
PURPOSE: Early mortality in multiple myeloma (MM) is usually attributed to combined effects of active disease and comorbid factors. We have studied early deaths in a series of large multicenter trials to assess direct causes of death, their predictability, and whether current management strategies have reduced their frequency. PATIENTS AND ...
Bussière Miguel - - 2005
BACKGROUND: Numerous therapeutic interventions have been developed in the neurosciences. Clinicians need summary measures about efficacy of therapies that derive from the best available evidence, and that can be readily extrapolated to clinical practice. The number needed to treat (NNT) is intuitive and clinically applicable. We provide clinicians with a ...
Bell R F - - 2005
BACKGROUND: Post-operative pain management is usually limited by adverse effects such as nausea and vomiting. Adjuvant treatment with an inexpensive opioid-sparing drug such as ketamine may be of value in giving better analgesia with fewer adverse effects. The objective of this systematic review was to evaluate the effectiveness and tolerability ...
Rosati Gerardo - - 2005
Patients > 65 years of age are the fastest growing segment of the cancer population. It is estimated that within 20 years, > 75% of cases and 85% of deaths from colorectal cancer (CRC) will be in this setting. Concerns about cancer treatment in the elderly relate to comorbidities, which ...
Ataman Ozlem Uruk - - 2006
BACKGROUND AND PURPOSE: The European Society for Therapeutic Radiology and Oncology was funded by the EU for a project on Recording providing Education, and Ameliorating the Consequences of Treatment (REACT). An important aim of follow-up (FU) after treatment for cancer is to detect various events associated with disease recurrence or ...
Stone Jon - - 2005
Paralysis, seizures, and sensory symptoms that are unexplained by organic disease are commonly referred to as "conversion" symptoms. Some patients who receive this diagnosis subsequently turn out to have a disease that explains their initial presentation. We aimed to determine how frequently this misdiagnosis occurs, and whether it has become ...
Meier Amalia S - - 2005
Randomization in clinical trials minimizes differences between treatment arms, allowing observed treatment differences to be attributable to an intervention. For prospective clinical trials, we examine the effects on inference when other specified treatment arm differences are also present. These differences are imposed using three measures: time between the unobserved failure ...
Karlsson Magnus K - - 2005
During the last decade, two new treatment modalities for osteoporotic vertebral fractures have gained more interest: percutaneous vertebroplasty and kyphoplasty. The techniques and the short-term clinical results and complications have been presented but there is no scientific evidence-based information regarding the efficacy of the procedures, such as randomized controlled trials ...
Todd Richard W - - 2005
OBJECTIVE: To determine which nonsurgical treatments have been assessed for the treatment of vulvar intraepithelial neoplasia (VIN) and what the outcomes of such treatment might be. MATERIALS AND METHODS: The English literature over the last 25 years was searched on Medline. RESULTS: A wide variety of nonsurgical treatments was identified ...
Shah Nirav R - - 2005
To date, no management approach has proven to be efficacious for the treatment of idiopathic pulmonary fibrosis (IPF). Consequently, therapeutic options remain controversial and confusing for many clinicians. We sought to formally review available evidence on treatment options for IPF and to have a diverse panel of physicians rate the ...
Marang-van de Mheen P J PJ Department of Medical Decision Making, Leiden University Medical Centre, The Netherlands. - - 2005
To assess the effectiveness of routine reporting to identify surgical adverse outcomes in comparison with retrospective medical record review. Independent assessment of two methods applied to one sample. Surgeons and surgical residents routinely reported all adverse outcomes for patients in their care during admission. A trained research assistant, blinded to ...
Hanif Mohammed - - 2005
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether the use of gene therapy could relieve angina symptoms in patients who are not amenable to conventional revascularisation strategies. Altogether 60 papers were identified using the search below. Seven papers presented ...
Shefet Daphna - - 2005
BACKGROUND: Current guidelines of empirical antibiotic treatment for inpatients with community-acquired pneumonia recommend antibiotics whose spectrum covers intracellular (atypical) pathogens. No sufficient evidence exists to support the necessity of such coverage, whereas limiting it may reduce toxic effects, resistance, and expense. Our goal was to assess the efficacy of empirical ...
Gnanalingham Kanna K - - 2005
OBJECT: The aim of this study was to evaluate the quality of clinical studies appearing in neurosurgical journals during three decades. METHODS: Clinical studies published in 1982, 1992, and 2002 in Neurosurgery, Journal of Neurosurgery (JNS), and British Journal of Neurosurgery (BJN) were evaluated. The feature study types were categorized ...
van der Meijden Adrian P M - - 2005
On behalf of the European Association of Urology (EAU), guidelines for the diagnosis, therapy and follow-up of patients with urothelial carcinoma in situ (CIS) have been established. The recommendations in these guidelines are based on a recent comprehensive overview and meta-analysis in which two panel members have been involved (RS ...
Taylor Stephanie J C - - 2005
To determine the effectiveness of innovations in management of chronic disease involving nurses for patients with chronic obstructive pulmonary disease (COPD). Systematic review of randomised controlled trials. 24 electronic databases searched for English or Dutch language studies published between January 1980 and January 2005. Included studies described inpatient, outpatient, and ...
Patel Atul T - - 2005
This evidence-based review was performed to evaluate the utility of nerve conduction studies (NCSs) and needle electromyography (EMG) in the diagnosis of tibial neuropathy at the ankle (tarsal tunnel syndrome, TTS). A total of 317 articles on TTS were identified that were published in English from 1965 through April 2002, ...
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