Search Results
Results 251 - 300 of 5082
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Lampertico Pietro - - 2012
ObjectiveTreatment with peginterferon α-2a (PegIFN) for 48 weeks is the standard of care for selected HBeAg-negative patients chronically infected with hepatitis B virus (HBV), but with limited treatment efficacy. A study was undertaken to investigate whether treatment extension to 96 weeks improves the outcome in this patient population.Methods128 HBeAg-negative patients ...
Wan Grace - - 2012
PURPOSE: Exposure to ionizing radiation during electrophysiologic procedures in children is believed to increase the risk of future malignancy. Electroanatomical navigation can reduce exposure, but the cohort of children who derive the greatest benefit from this approach is incompletely defined. We sought to determine factors associated with fluoroscopy exposure with ...
Mueller V T - - 2012
Mueller VT, Welch K, Bratu DC, Wang H-L. Early and late studies of EMD use in periodontal intrabony defects. J Periodont Res 2012; doi: 10.1111/j.1600-0765.2012.01510.x. © 2012 John Wiley & Sons A/S Background and Objective:  The clinical efficacy of EMDs for the treatment of periodontal infrabony defects has been reported. ...
Schmiedt Chad W - - 2012
Case Description-A 1.5-year-old mixed-breed dog was examined because of a 1-month history of anorexia, vomiting, diarrhea, and weight loss. Clinical Findings-The dog was very thin on physical examination (body condition score, 3/9). Results of all diagnostic tests were within reference limits except intestinal thickening and lymphadenopathy were identified on abdominal ...
Lim H-C - - 2012
Medium-term survivorship of the Oxford phase 3 unicompartmental knee replacement (UKR) has not yet been established in an Asian population. We prospectively evaluated the outcome of 400 phase 3 Oxford UKRs in 320 Korean patients with a mean age at the time of operation of 69 years (48 to 82). ...
Zhang Yun-Dong - - 2012
Objective: To elucidate the therapeutic effect of subtemporal decompressive craniotomy with large flap resection on serious craniocerebral injury associated with cerebral infarction. Methods: Forty-eight cases of serious head injury accompanied by cerebral infarction were classified into two groups with each having 24 cases: treatment group, in which large bone-flap decompressive ...
Lu F - - 2012
Background:  Chinese Hypertension Intervention Efficacy (CHIEF) study is a large-scale randomised clinical trial across China, which compares the efficacy of two combination regimens in reducing cardiovascular events associated with hypertension. Methods:  We reported the 48-week efficacy and tolerability of the two antihypertensive regimens in participants from Shandong Province, China. Eligible ...
Markham A Catherine - - 2012
In many social species, competition between groups is a major factor proximately affecting group-level movement patterns and space use and ultimately shaping the evolution of group living and complex sociality. Here we evaluated the factors influencing group-level dominance among 5 social groups of wild baboons (Papio cynocephalus), in particular focusing ...
Schoenfeld Andrew J - - 2012
Retrospective review of the data collected prospectively through the Spine Patient Outcomes Research Trial (SPORT). To determine the effect that race or ethnicity had on outcomes after spine surgery in the 3 arms of SPORT. There is a dearth of research regarding the effect of race or ethnicity on outcome ...
Sevick Mary Ann MA Pittsburgh Healthcare System and the School of Medicine, University of Pittsburgh,230 McKee Pl, Pittsburgh, PA 15213, USA. - - 2012
Behavioral research to improve lifestyle in broadly defined populations of patients with type 2 diabetes is limited. We evaluated a behavioral intervention featuring technology-based self-monitoring on biophysiologic outcomes of glycemic control and markers of cardiovascular risk. In this single-site, randomized clinical trial, participants were stratified by good and poor glycemic ...
Lawhorn Keith W - - 2012
To compare the results and outcome of anterior cruciate ligament (ACL) reconstruction using autogenous hamstring tendon versus fresh-frozen allograft anterior tibialis tendon. A prospective randomized study was conducted from September 2002 to October 2006. We randomized 147 patients to undergo ACL reconstruction with either autogenous hamstring or fresh-frozen allograft anterior ...
Nieuwenhuijse Marc J - - 2012
As the number of young patients receiving total hip arthroplasty increases, bone-saving implantations facilitating possible future revision, such as the CUT femoral neck prosthesis, are gaining importance. There have been few medium-term results reported for this prosthesis, however, and its migration pattern has not been analyzed. 39 consecutive CUT femoral ...
van Garsse Leen - - 2012
BACKGROUND: We evaluated the papillary muscle systolic dyssynchrony (DYS-PAP) using two-dimensional speckle tracking echocardiography (2D-STE) in patients with chronic ischemic mitral regurgitation (CIMR) showing different preoperative leaflet pattern and investigated the impact of baseline tethering pattern in the prediction of significant post-repair desynchronized papillary muscle contraction. METHODS: We recruited 152 ...
Sanchez Judith - - 2012
Study objective: To determine the usefulness of the pictorial blood assessment chart (PBAC) for use as a valid screening tool for menorrhagia in adolescents. Study design: To conduct a prospective survey paired with retrospective chart review. Main outcome measures: To determine mean PBAC scores among adolescents presenting with menorrhagia versus ...
Toghraie Fatemehsadat - - 2012
Osteoarthritis (OA) is the most common form of arthritis seen clinically. Current treatments for OA are limited to decreasing associated pain, maintaining or improving joint function, and minimizing disability. However, these treatments have no effect on the regeneration of hyaline cartilage. Since mesenchymal stem cells (MSCs) have been described as ...
Zhang Shi-Jin - - 2012
To discuss the clinical effects of Western medicine therapy assisted by Ginkgo biloba tablet (GBT) on patients with vascular cognitive impairment of none dementia (VCIND). A total of 80 patients with VCIND were divided into two groups randomly: Conventional treatment group (control group) and combined treatment group. Conventional treatment group ...
Jia Yu-Tao - - 2012
Objective: To detail our early experience and technique of a modified two-stage reimplantation protocol using antibiotic-loaded articulating cement spacers (ALACSs) for treatment of late periprosthetic infection after total knee arthroplasty (TKA). Methods: From January 2006 to February 2009, a series of 21 patients (21 knees) with late infected TKAs were ...
Lee Jung Il - - 2012
A retrospective analysis was performed based on the medical records and imaging studies of 16 wrists (14 patients) with isolated partial intercarpal ligament tears (scapholunate ligament: 6 wrists, lunotriquetral ligament, 10 wrists) treated with arthroscopic debridement and thermal shrinkage. Three wrists had Geissler grade 1 tears and 13 wrists had ...
Turgut Ali - - 2012
In this study, we aimed to evaluate changes in frontal plane (anatomical axis) and sagittal plane (tibial slope, patellar height) parameters following closed-wedge high tibial osteotomy (HTO) and possible correlations between them. Between June 2003 and May 2007, 15 knees of the 13 female patients (mean age 52.6 years; range ...
Wong Fergus F - - 2012
Exogenous collagen cross-linking has been investigated as method of reinforcing scleral biomechanics, with the goal of counteracting scleral weakening that occurs at the onset of myopia. This study uses whole globe inflation testing to investigate the biomechanical effect of treating posterior sclera with the collagen cross-linking agents methylglyoxal and genipin. ...
Meuffels Duncan E - - 2012
The Dutch Orthopaedic Association has a long tradition of development of practical clinical guidelines. Here we present the recommendations from the multidisciplinary clinical guideline working group for anterior cruciate ligament injury. The following 8 clinical questions were formulated by a steering group of the Dutch Orthopaedic Association. What is the ...
Forbes Thomas L - - 2012
Failure of endovascular repair (EVAR) of an abdominal aortic aneurysm can result in significant risk of morbidity and mortality. We review our experience with late conversions to open repair. We conducted a retrospective database review to identify all EVAR procedures performed between 1997 and 2010 and the number converted to ...
Riad Waleed - - 2012
To compare metal posterior, flexible posterior, and flexible medium sub-Tenon cannulas for akinesia and anesthesia. King Khaled Specialist Eye Hospital, Riyadh, Saudi Arabia. Prospective blind randomized comparison. Patients having cataract surgery under sub-Tenon block received a mixture of bupivacaine and lidocaine with hyaluronidase. The patients were divided into 3 groups ...
Hampton Daniel M - - 2012
Anterior cruciate ligament reconstruction with patellar tendon allograft tissue is a common orthopedic procedure. It is unknown what effect, if any, the donor age has on clinical outcomes. Biomechanical studies have shown the strength of cadaveric patellar tendon to be independent of age, but no clinical studies have evaluated patient ...
Schwab Frank - - 2012
: The Schwab-SRS Classification of Adult Spinal Deformity (ASD) is a validated system that provides a common language for the complex pathology of ASD. Classification reliability has been reported; however, correlation with treatment has not been assessed. Purpose: assess association between disability, classification type/modifier and ASD treatment. : Prospective analysis ...
Laeeq Kulsoom - - 2012
OBJECTIVES/HYPOTHESIS: To this date the effect of the time taken to complete an evaluation on the psychometric properties of the instrument has not been reported. The goal of our study was to assess the effect of time taken to complete an evaluation on its validity. STUDY DESIGN: Cross-sectional validation study. ...
Dragun Anthony E - - 2012
In 2001 ASCO published practice guidelines for post mastectomy radiotherapy (PMRT). We analyzed factors that influence the receipt of radiotherapy therapy and trends over time. We analyzed 8889 women who underwent mastectomy as primary surgical treatment for stage II or III breast cancer between 1995 and 2008 using data from ...
Kim Man Deuk - - 2012
The purpose of this study was to evaluate the safety of pretreatment with gonadotropin-releasing hormone (GnRH) agonists before uterine artery embolization (UAE) of large fibroids. The cases of 40 patients with large fibroids (≥ 10 cm) were retrospectively analyzed. Among the 40 patients, 28 (control group) underwent UAE without pretreatment ...
Misterska Ewa - - 2012
There are many factors influencing postoperative health-related quality of life of adolescent idiopathic scoliosis patients, including the degree of the deformity, culture, differences in geography, rural versus urban living environments, and social factors. The objective of this study was to analyze the significance of geographic factors and their differences influencing ...
Zhang Qiang - - 2012
To prospectively compare therapeutic effect of femoral tunnel preparation through the tibial tunnel and the anteromedial (AM) portal in single-bundle anterior cruciate ligament (ACL) reconstruction. Between June 2008 and October 2010, 76 patients underwent single-bundle ACL reconstruction by autogenous grafting of semitendinosus and gracilis tendon. All cases were randomly divided ...
Hernandez Fernando - - 2012
Intensive management is almost the only way to ensure dairy farm profitability. The dry period length (DPL) is a key factor in the productivity and health of dairy cows, but whether the same is true of dairy sheep is unclear. This study investigated the effects of DPL on the performance ...
Mohanty Aaron - - 2012
: Of various management options for isolated fourth ventricle (IFV), fourth ventricular shunts (FVPS) and aqueductal stents (AST) have been the most favored. Though effective, 4th ventricular shunts are often difficult to place and are reported to have higher complication rates than conventional ventricular shunts. : Twenty-two patients (3 months ...
Adeyemi Moshood F - - 2012
This study was undertaken to compare the healing outcome of a short period (2 weeks) of intermaxillary fixation (IMF) with conventional (4-6 weeks) IMF in the management of fractures of the mandibular tooth-bearing area. This was a randomized controlled study conducted at the Lagos University Teaching Hospital, Lagos, Nigeria, between ...
Shen F-C - - 2012
Objective:  To use a meta-analysis approach to evaluate the efficacy and safety of purine analogues, azathioprine (AZA) and 6-mercaptopurine (6-MP), in the prevention of postoperative recurrence of Crohn's disease (CD), as compared with mesalamine or 5-aminosalicylic acid (5-ASA). Methods:  The Pubmed, Cochrane Library, and Embase literature databases were searched for ...
Mayer-Wagner Susanne - - 2012
Radiosynoviorthesis (RSO) has been established as a treatment modality for rheumatoid arthritis. Other forms of joint diseases like recurrent joint effusions after knee arthroplasties are under investigation. The aim of this study was to examine whether RSO therapy is effective in the application of an endoprosthesis and whether there are ...
Thomsen Morten G - - 2012
Between 2004 and 2009, the incidence of primary total knee arthroplasty (TKA) in Denmark has almost doubled. It has been speculated that this increase may be a result of patients being operated on weaker indications. The purpose of this study was to compare preoperative degrees of osteoarthritis and health-related quality ...
Rai Anshul - - 2012
The intention of this study was to compare the efficacy of eyelet wiring and direct interdental (Gilmer) wiring for achieving intermaxillary fixation (IMF). This study was a prospective randomized clinical trial. The study sample was derived from the population of patients who underwent IMF at the Department of Oral and ...
Oen Irma M M H IM Burn Centre, Maasstad Hospital, Rotterdam, The - - 2012
The face is a very frequent site of burn injuries. This multicenter, randomized, controlled trial thus investigates the effectiveness of cerium nitrate-silver sulfadiazine in the treatment of facial burns compared with silver sulfadiazine. Adult patients with acute facial burns admitted to Dutch burn centers were randomized to treatment with either ...
Kim Dong Chan - - 2012
Reoperation of cardiac surgery via median sternotomy can be associated with significant complications. Thoracotomy is expected to reduce the risk of reoperation and to enhance the surgical outcomes. We retrospectively analyzed two operative approaches (thoracotomy vs. sternotomy) in cardiac reoperation. From September 2007 to December 2010, 35 patients who required ...
Sabria Joan - - 2012
Objective: To update the reference ranges for the ductus venosus pulsatility index (DVPI) at 11+0 to 13+6 gestational weeks. Methods: DVPI was calculated in 14,444 singleton fetuses at 11+0 to 13+6 weeks in two Fetal Medicine Centers, during a 4-year period. Using previously described medians, DVPI evolution was assessed both ...
de Simone Vito - - 2012
The popliteus tendon is known to play a key role in the stability of the posterolateral corner of the knee. While prior work suggests that isolated sectioning of the popliteus tendon has little consequence for the static stability of the knee following TKA, no studies have evaluated the effect of ...
Garrigues Grant E - - 2012
Rupture of the pectoralis major is an uncommon injury that can lead to pain, loss of strength, and cosmetic deformity. The purpose of this study was to analyze the outcome of pectoralis major repairs by a single surgeon.Twenty-four patients who underwent pectoralis major repair by the senior author (M.D.L.) between ...
Daniel Roy Thomas - - 2012
: Disconnective surgery provides excellent seizure outcome for the group of patients with sub-hemispheric or hemispheric epilepsy when the indication criteria are strictly applied. However, data on cognitive outcome following surgery has not been properly documented for these patients in previous studies. : Sixteen patients underwent surgery between 2005 and ...
Yang Ding-Quan - - 2012
To observe the efficacy and safety of total glucosides of paeony capsule (TGPC) in patients with mild and moderate alopecia areata. A total of 86 outpatients were randomly allocated into two groups of TGPC (treatment, 44 cases) and compound glycyrrhizin tablet (control, 42 cases). The treatment group was given oral ...
Moghadam Morteza Jabbari - - 2012
Clonidine, an alpha-2 adrenergic agonist, increases the quality of perioperative sedation and analgesia with a few side effects. This study was designed to assess the effect of clonidine premedication on the anesthesics used for elective below knee surgeries in opium abusers and non-abusers. In a randomized clinical trial, 160 patients ...
Citerio Giuseppe G Neuroanesthesia and Neurointensive Care Unit, Anestesia e Rianimazione, San Gerardo Hospital, via Pergolesi 33, Monza 20900, Milano, Italy. - - 2012
A clear preference for intravenous or inhalational anaesthesia has not been established for craniotomy in patients without signs of cerebral hypertension. The NeuroMorfeo trial was designed to test equivalence of inhalational and intravenous anaesthesia maintenance techniques in the postoperative recovery of patients undergoing elective supratentorial surgery. This trial is a ...
Gumina Stefano - - 2012
Arthroscopic rotator cuff repair generally provides satisfactory results including decreased shoulder pain and improved shoulder motion. Unfortunately, imaging studies demonstrate that the retear rate associated with the available arthroscopic techniques may be high. The purpose of this study was to evaluate the clinical and magnetic resonance imaging (MRI) results of ...
Otero Pablo E - - 2012
Objective-To determine the minimal electric threshold of neurostimulation dorsally and ventrally to the interarcuate ligament in the lumbosacral area necessary to cause muscle contraction of the hind limb or tail and determine whether a continuous electrical stimulation applied to an insulated needle during lumbosacral epidural needle placement could be used ...
Apostolakis Stavros - - 2012
The objective of this study was to compare the predictive performance of bleeding risk-estimation tools in a cohort of patients with atrial fibrillation (AF) undergoing anticoagulation. Three bleeding risk-prediction schemes have been derived for and validated in patients with AF: HEMORR(2)HAGES (Hepatic or Renal Disease, Ethanol Abuse, Malignancy, Older Age, ...
Diao Mei - - 2012
Routine drain placement after choledochal cyst (CDC) excision and Roux-en-Y hepatojejunostomy (RYHJ) is commonly practiced to predict and prevent bile/pancreatic leaks and hemorrhage. Recently, laparoscopic excision of CDC has decreased postoperative morbidity. The necessity of drainage has been questioned. We undertook a prospective randomized trial to assess the need for ...
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