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Pattaravit Ngamjit N Department of Anesthesia, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand. - - 2013
Evaluate the effect of intravenous fentanyl on the incidence and severity of EA. In the clinical trial, 144 patients aged between two and nine years, scheduled for elective surgery were enrolled and randomly assigned to receive either fentanyl 1 microg/kg or normal saline 1 ml/10 kg, 15 minutes before the ...
Ferman Tanis J - - 2013
To determine the rate of progression of mild cognitive impairment (MCI) to dementia with Lewy bodies (DLB). We followed 337 patients with MCI in the Mayo Alzheimer's Disease Research Center (range 2-12 years). Competing risks survival models were used to examine the rates of progression to clinically probable DLB and ...
Arazpour Mokhtar - - 2013
Background:Knee-ankle-foot orthoses are utilized for walking by patients with lower limb weakness. However, they may be rejected by patients due to the lack of knee flexion available when using them for walking activities.Aim:The aim of this study was to perform a pilot study investigating the effect of a new powered ...
Holt P J E PJ Department of Outcomes Research, St George's Vascular Institute, St George's Healthcare NHS Trust, London, - - 2012
Long-term concerns about the durability of endovascular aortic aneurysm repair (EVAR) remain after the publication of controlled trials. Increased expertise in endograft technology, case selection and postoperative reintervention has created a need for reappraisal of the longer-term efficacy of EVAR using contemporary data. Patients undergoing infrarenal EVAR between 2004 and ...
Harsten Andreas - - 2012
CONTEXT: Perioperative oral carbohydrate intake is beneficial to general surgery patients. Total hip arthroplasty is a common surgical procedure, and even a moderate improvement in patient outcome could have a significant effect on the resources needed for these patients. However, few studies have focused on the effects of carbohydrate intake ...
Zhuang Zhi-Guo - - 2012
Portal hyperperfusion in the small-for-size (SFS) liver can threaten survival of rabbits. Therefore, it is important to understand the hemodynamic changes in the SFS liver. Twenty rabbits were divided into two groups: a control group and a modulation group. The control group underwent an extended hepatectomy. The modulation group underwent ...
Khalil Sumaira - - 2012
Cholestatic jaundice and liver enzyme abnormalities have been reported in neonatal septicaemia; the course, pattern, and outcome of such hepatobiliary dysfunction have not been described. One hundred fifty-three neonates with blood culture-positive sepsis were recruited from the neonatal intensive care unit of an urban hospital. Liver function tests were done ...
Kribben Andreas - - 2012
Fractionated plasma separation and adsorption (FPSA) is an extracorporeal procedure that supports liver function by removing endogenous toxins that cause complications from acute-on-chronic liver failure (AOCLF). We performed a randomized trial to investigate survival of patients with AOCLF treated with FPSA. Patients with AOCLF were randomly assigned to groups given ...
Tanaka Hironori - - 2012
Aim:  Sonazoid is a new contrast agent for ultrasonography (US). Contrast-enhanced ultrasonography (CEUS) using Sonazoid enables Kupffer imaging, which improves the sensitivity of hepatocellular carcinoma (HCC) detection. However, there are no studies on the cost-effectiveness of HCC surveillance using Sonazoid. Methods:  We constructed a Markov model simulating the natural history ...
Cholongitas Evangelos - - 2011
Acetaminophen-induced acute liver failure (ALF) is a complex multi organ illness. Assessment of prognosis is essential for accurate identification of patients in whom survival without liver transplantation (LT) is unlikely. The aim of the study was to compare prognostic models (King's, MELD, SOFA and APACHE II) and to identify independent ...
Ausania Fabio - - 2011
BACKGROUND: Right accessory hepatic artery (RAHA) injury at retrieval is a rare complication of deceased liver procurement. Arterial reconstruction is often required under these circumstances which could potentially increase the risk of hepatic artery thrombosis (HAT). The aim of this study is to investigate whether RAHA injury affects the incidence ...
Pietu Florence - - 2011
BACKGROUND: The combination of ursodeoxycholic acid (UDCA) and vitamin E is a therapeutic option for nonalcoholic steatohepatitis (NASH) but randomized controlled studies have produced inconsistent results. The objective of this study was to report the long-term tolerability and efficacy of this combination in our ten-year single center experience. METHODS: The ...
Muhammed Rafeeq - - 2011
BACKGROUND:: Resolution of parenteral nutrition (PN) associated jaundice has been reported in children given a reduced dose of intravenous fat using a fish oil derived lipid emulsion. OBJECTIVES:: To examine to effect on PN associated jaundice of changing from a soya oil derived lipid (Intralipid, Fresenius Kabi) to a mixed ...
Tulchinsky Mark - - 2011
: Tc-99m-mebrofenin clearance rate is used to estimate hepatocellular function. This investigation studied effect of labeling-to-administration (LTA) time of Tc-99m-mebrofenin and its liver clearance rate. : A total of 15 patients, age 46 ± 13 (range, 19-69) years, referred for routine gallbladder ejection fraction testing, were retrospectively studied. All had ...
Chrispijn M - - 2011
Background  Polycystic liver disease (PLD) is a phenotypical expression of autosomal dominant polycystic kidney disease and isolated polycystic liver disease. Somatostatin analogues, such as lanreotide, reduce polycystic liver volume. Aim  To establish long-term outcome and safety of lanreotide. Methods  This was an open-label, observational extension study of a 6-month, randomised, ...
Fransen van de Putte D E - - 2011
Summary.  Hepatitis C infection is a major comorbidity in patients with inherited bleeding disorders. Successful antiviral treatment leads to a reduction in liver fibrosis, as shown by liver biopsies. Liver stiffness measurement (LSM) is a non-invasive method of assessing liver fibrosis. The aim of this cohort study was to evaluate ...
Imura Satoru - - 2011
PURPOSE: The liver-hanging maneuver (LHM) is a useful technique in major hepatectomy. We made modifications to this technique with special reference to the ligamentum venosum for performing a left hepatectomy (LH). The aim of this study was to clarify the usefulness of our new technique. METHODS: Between August 2007 and ...
Tran Nhut Quang - - 2012
  Approaches to increase organ availability for orthotopic liver transplantation (OLT) often result in the procurement of marginal livers that are more susceptible to ischaemia, preservation and reperfusion injury (IPRI).   The effects of post-OLT hyperbaric oxygen (HBO) therapy on IPRI in a syngeneic rat OLT model were examined at ...
Orloff Marshall J - - 2011
OBJECTIVE: Ten years ago, we reported our results with what remains as the largest clinical experience with surgical portal decompression for Budd-Chiari syndrome (BCS) in the West. Since then, our series has expanded to 77 patients, and there has been an explosion of interest in and publications about BCS. The ...
Savier E - - 2011
SCOT 15 is a new solution to preserve abdominal organs for transplantation. Its principal characteristic is the use of polyethylene glycol. Herein We report our experience using SCOT 15 compared with the reference University of Wisconsin (UW) solution for hepatic transplantation. We compared 2 groups: SCOT 15 (n = 33; ...
Beyaz Serbülent Gökhan - - 2011
Although most general anaesthesia procedures are performed without any complications, volatile agents may have adverse effects on various living systems. This study aims to compare the antioxidant effects of isoflurane and N-acetylcysteine (NAC) on liver function. Forty-one patients in the ASA I-II risk groups, who were scheduled to undergo gynaecologic ...
Ghany Marc G - - 2011
Predicting clinical outcomes in patients with chronic hepatitis C is challenging. We used the hepatitis C long-term treatment against cirrhosis (HALT-C) trial database to develop two models, using baseline values of routinely available laboratory tests together with changes in these values during follow-up to predict clinical decompensation and liver-related death/liver ...
Nakamura Hiroki - - 2011
BACKGROUND: The portoenterostomy (PE) procedure for treating biliary atresia (BA) has been so repeatedly modified that it currently hardly resembles Kasai's original PE (KOPE). Now PE involves an extended lateral dissection and a wide anastomosis (extended PE: EPE). We reappraised KOPE and created our-KOPE (OKOPE) by adhering strictly to its ...
Prabu P C - - 2011
New Zealand White rabbits, divided into 4 groups were fed with feed containing aflatoxin B(1) (AFB(1)) @ 0.5ppm (group I), ochratoxin A (OA) @ 1ppm (group II), AFB(1) and OA @ 0.5ppm and 1ppm, respectively (group III) and standard feed (group IV) for 60 days. Mortality and decrease in body ...
Zhang Yue - - 2011
INTRODUCTION:: To study and evaluate the immunosafety of our newly developed multilayer flat-plate bioartificial liver (BAL) in treatment of canines with acute liver failure. METHODS:: Fresh porcine hepatocytes and bone marrow mesenchymal stem cells were cocultured in new BAL. Ten canine models with acute liver failure were set up through ...
Motosugi Utaroh - - 2011
PURPOSE: To evaluate individual differences in liver stiffness measurement using both MR elastography (MRE) and ultrasound transient elastography (UTE) in patients with chronic liver disease. MATERIALS AND METHODS: This study included 80 patients with chronic liver disease who underwent both UTE and MRE. MRE and UTE were performed using a ...
El-Ansary Mervat - - 2011
The study was aimed to evaluate the effect of autologous transplantation of BM-derived undifferentiated and differentiated MSCs in cirrhotic patients following chronic hepatitis C virus infection. Twenty-five patients with Child C liver cirrhosis, MELD score >12 were included. They were divided into 2 groups. Group I, the MSCs group (n = 15), ...
Kamohara Yukio - - 2011
Background/Aims: Indocyanin Green (ICG)-based diagnosis is widely accepted in determination of hepatic resection range, however, we frequently encounter scattered results of preoperative assessment. The aim of this study was to clarify the role of 99mTc Galactosyl sialyl albumin (GSA) scintigram in the decision of the resection range. Methodology: One hundred ...
Okabayashi Takehiro - - 2011
BACKGROUND: Intensive insulin therapy (IIT) reduces morbidity and mortality in patients in surgical care units, yet the benefits of IIT during liver surgery, especially on liver function after hepatic resection, are not known. The aim of the present study was to assess the effects of IIT, with a focus on ...
Torzilli Guido - - 2011
OBJECTIVE:: We retrospectively compared the short-term outcome of a consecutive cohort of patients who underwent hepatectomy with intermittent clamping ranging between 60 and 120 minutes with those having a clamping time exceeding 120 minutes. BACKGROUND:: Intermittent Pringle maneuver is widely used to minimize blood loss during hepatectomy, without an established ...
Zhao Xiaochen - - 2011
OBJECTIVES: To explore the haemostatic effects of microbubble-enhanced ultrasound (MEUS) at a very low acoustic intensity on the bleeding liver of rabbits. METHODS: Liver incisions made on 20 rabbits were treated with a pulsed therapeutic ultrasound transducer. The transducer was operated at 831 KHz with an acoustic intensity of 0.4 W/cm(2). ...
Yurci Alper - - 2011
BACKGROUND AND AIMS: Metabolic bone disease is common in patients with chronic liver disease. Comparative studies on the efficacies of antiosteoporotic agents in hepatic osteodystrophy have not been conducted yet. The aim of this study was to evaluate the safety and efficacy of different therapeutic regimens on hepatic osteodystrophy. METHODS: ...
Zhou Qi - - 2011
Imaging-guided thermal ablation using different energy sources continues to gain favor as a minimally invasive technique for the treatment of primary and metastatic hepatic malignant tumors. This study aimed to evaluate the performance of microwave ablation with 2450-MHz internally cooled-shaft antenna in ex vivo and in vivo porcine livers. All ...
Ren Zuhai - - 2011
Background/Aims: To investigate the role of indocyanine green (ICG) retention test in avoiding postoperative liver failure after hepatectomy for primary hepatolithiasis. Methodology: Between January, 2004 and December, 2010, 144 patients with primary hepatolithiasis undergoing hepatectomy were retrospectively selected for the study. Eighty-two of those (Group CP) were preoperatively evaluated only ...
Guang Cao - - 2011
The aim of the study was to clarify the effect of the interval between transcatheter hepatic arterial embolization (TAE) with Lipiodol plus gelatin sponge particles and radiofrequency (RF) ablation on the extent of ablation. Eight healthy swine were divided into four groups: RF ablation (ablation only), RF ablation immediately after ...
Williams Suzan - - 2011
Neonatal portal vein thrombosis (PVT) is an increasingly recognized event. Patients are generally asymptomatic in the neonatal period. The diagnosis is made with Doppler ultrasound. Umbilical catheterization, exchange transfusion and sepsis are risk factors for neonatal PVT. Thrombophilia is possibly a contributing risk factor. Although there are potential serious acute ...
Ogawa Eiichi - - 2011
Aim:  To evaluate the association between liver stiffness measured by transient elastography (FibroScan) and the efficacy of long-term nucleoside analog (NA) treatment for patients with chronic hepatitis B. Methods:  Study 1: Forty-four chronic HBV patients had liver stiffness measured by FibroScan and underwent liver biopsy. Study 2: Group A: 22 ...
Aller R - - 2011
The present pilot trial was carried out to evaluate the effects of an acute treatment with a mixture containing 500 million of Lactobacillus bulgaricus and Streptococcus thermophilus per day in patients with non alcoholic fatty liver disease (NAFLD). A sample of 30 patients with NAFLD (diagnosed by liver biopsy) was ...
Huang Ke-Feng - - 2011
Abstract Objectives: In Traditional Chinese Medicine (TCM), Qi maintains the physiologic function and indicates physiologic energy. Glucose provides energy to humans, thereby playing a role analogous to "nutritive Qi." This study aims to identify the correlations among blood glucose, Qi Vacuity (QV), and the electrical conductances of acupoints. Methods: Twenty ...
Li Chuan - - 2011
Background/Aims: This study aimed to evaluate the postoperative outcomes of patient with a graft with graft to body weight ratio (GBWR) less than 0.8% after living donor liver transplantation (LDLT) using the right hepatic lobe without middle hepatic vein (MHV). Methodology: The clinical data of patients who underwent LDLTs using ...
Poley Jan-Werner - - 2011
Most benign biliary strictures nowadays are managed endoscopically with plastic stents or with a insertion of a fully covered self-expandable metal stent (fcSEMS). The paradigm for the treatment of benign hilar strictures precludes the use of an fcSEMS because it obstructs the intrahepatic bile ducts, in particular, the contralateral hepatic ...
Leclère F M - - 2011
BACKGROUND: The use of an operating microscope in animal liver surgery has made it possible to obtain new experimental models. The goal of this prospective animal study is to present our experience with dogfish portocaval microanastomoses. METHODS: Nineteen portocaval microanastomoses were performed in dogfish. The end-to-side anastomoses were accomplished using ...
Hong Johnny C - - 2011
OBJECTIVE:: To develop a prognostic scoring system for risk stratification of patients with hepatic graft failure (GF) undergoing retransplants of the liver (ReLT) and improve patient selection. SUMMARY OF BACKGROUND DATA:: Retransplantation of the liver remains controversial because of inferior outcomes compared with the primary orthotopic liver transplantation (OLT) and ...
Viganò Luca - - 2011
BACKGROUND: Pedicle clamping during liver resection (LR) is debated. The purpose of this study is to validate non-clamping policy across a large series of LR and to evaluate the need for salvage clamping (SC) and its outcomes. METHODS: Five hundred twelve consecutive LR without initial pedicle clamping performed between 2004 ...
Gandini Alessandro - - 2011
BACKGROUND: Bleeding is the main cause of postoperative complications of hepatic surgery. To minimize intraoperative bleeding during hepatectomy, resections are generally carried out under hepatic vascular control despite the risk of liver dysfunction in patients with chronic liver disease. This study evaluates the feasibility and safety of high-intensity focused ultrasound ...
Wang Hai-Qing - - 2011
To evaluate the clinical outcomes of patients undergoing hepatectomy with hemihepatic vascular occlusion (HHO) compared with total hepatic inflow occlusion (THO). Randomized controlled trials (RCTs) comparing hemihepatic vascular occlusion and total hepatic inflow occlusion were included by a systematic literature search. Two authors independently assessed the trials for inclusion and ...
Tong Ying - - 2011
Background/Aims: This non-randomized study aimed to compare the perioperative outcomes of complete hemihepatic vascular exclusion (CHVE) vs. Pringle maneuver in partial hepatectomy. Methodology: From February 2006 to September 2008, 129 consecutive patients with resectable tumors confined to a hemi-liver underwent hepatic resection with CHVE (n=55) or Pringle maneuver (n=74). The ...
Zhu Ling-Hua - - 2011
It is difficult and time-consuming for carrying out conventional hand-sewn bilioenteric anastomosis, especially for small bile duct anastomosis and laparoscopic procedure. In order to simplify it, we have developed a novel procedure of sutureless bilioenteric anastomosis with an intraluminal degradable stent. This study aimed to evaluate the feasibility and safety ...
Aoki Taku - - 2011
BACKGROUND: We investigated the long-term profiles of liver regeneration after living-donor hepatectomy. METHODS: Thirty-three donors participated in the study. Preoperative and postoperative liver volume was calculated using computed tomography. Volume assessment was repeated at 1 week, 2 weeks, 1 month, 3 months, 6 months, 12 months, and 4 years postoperatively. RESULTS: Donors were divided into the right ...
Yang Huayu - - 2011
BACKGROUND:: The inhibition of inflammation exerts benefits following massive hepatectomy in animals but not in the clinic. The aim of this study was to investigate the effectiveness and mechanism of ulinastatin on liver function and outcomes following hepatectomy. METHODS:: One hundred seventy-six patients undergoing hepatectomy were randomized into the treatment ...
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