Search Results
Results 201 - 250 of 1638
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Dey A - - 2010
INTRODUCTION: The management of recurrent pleural effusion or pneumothorax has always been a cause for serious concern among chest physicians. Among the wide variety of agents that are available for pleurodesis, povidone iodine is now perhaps the most sought after agent as it is cheap, easily available, effective and safe. ...
Suehiro Koichi - - 2010
To examine perioperative management and complications in patients undergoing pneumonectomy. Observational cohort study. University-affiliated city hospital. 65 patients who underwent unilateral pneumonectomy for resection of lung cancer between March 1997 and October 2007 were included in this study. Patients who underwent pneumonectomy were then classified into two groups: Group C ...
Souza Yglesio Moyses de - - 2010
The antibacterial effect of ozone (O(3)) has been described in the extant literature, but the role of O(3) therapy in the treatment of certain types of infection remains controversial. To evaluate the effect of intraperitoneal (i.p.) O(3) application in a cecal ligation/puncture rat model on interleukins (IL-6, IL-10) and cytokine-induced ...
Harmatz Paul - - 2010
Pulmonary function is impaired in untreated mucopolysaccharidosis type VI (MPS VI). Pulmonary function was studied in patients during long-term enzyme replacement therapy (ERT) with recombinant human arylsulfatase B (rhASB; rhN-acetylgalactosamine 4-sulfatase). Pulmonary function tests prior to and for up to 240 weeks of weekly infusions of rhASB at 1 mg/kg ...
Sanders Don B DB 1Division of Pulmonology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. USA. - - 2010
Lung function (FEV(1)) generally improves during treatment of pulmonary exacerbations in patients with cystic fibrosis (CF). However, it is unclear how often return to previous baseline FEV(1) is achieved. (1) To determine the proportion of pediatric patients with CF treated for a pulmonary exacerbation who fail to recover to baseline ...
Kaneko Kenitiro - - 2010
BACKGROUND: There are still few reports on thoracoscopic lobectomy in neonates. The rate of prenatally diagnosed congenital cystic lung diseases is increasing, and such diseases appear to be a good indication for thoracoscopic lobectomy. METHODS: We performed a prospective trial of thoracoscopic lobectomy for all congenital cystic lung diseases in ...
Ueda K - - 2010
BACKGROUND: Tiotropium, a long-acting bronchodilator, can be used perioperatively in patients with lung cancer and airway obstruction, although its benefits for the perioperative outcome remain unclear. METHODS: We prospectively collected the perioperative data of 44 patients with resectable lung cancer and untreated airway obstruction. Tiotropium was not used before September ...
Weingarten T N - - 2010
BACKGROUND: 'Open lung' ventilation is commonly used in patients with acute lung injury and has been shown to improve intraoperative oxygenation in obese patients undergoing laparoscopic surgery. The feasibility of an 'open lung' ventilatory strategy in elderly patients under general anaesthesia has not previously been assessed. METHODS: 'Open lung' ventilation ...
Pal Kamalesh - - 2010
Pulmonary growth in the survivors of congenital diaphragmatic hernia (CDH) still remains an intriguing issue. In the literature there are conflicting reports on pulmonary vascular growth in CDH. In a cohort of CDH patients treated without extracorporeal membrane oxygenation (ECMO), serial perfusion studies were conducted prospectively to follow the growth ...
Kikkawa Tomohiro - - 2010
There is a report that S100A12 is useful as an early marker of acute lung injury (ALI). The purpose of this study was to determine whether S100A12 or sRAGE is useful as a marker during the development of ALI in postoperative sepsis patients. The subjects were patients who underwent emergency ...
Bouhemad Bélaïd - - 2010
OBJECTIVES: To compare lung reaeration measured by bedside chest radiography, lung computed tomography, and lung ultrasound in patients with ventilator-associated pneumonia treated by antibiotics. DESIGN: Computed tomography, chest radiography, and lung ultrasound were performed before (day 0) and 7 days following initiation of antibiotics. SETTING: A 26-bed multidisciplinary intensive care ...
Guo Yubiao - - 2010
BACKGROUND AND OBJECTIVE: The mechanism by which iodopovidone achieves pleurodesis is unknown. This study investigated whether iodopovidone is as effective as doxycycline in producing pleurodesis and whether systemic corticosteroids diminish its efficacy. METHODS: Four groups of seven New Zealand rabbits were assigned to the following intrapleural treatment groups: 2 mL ...
Nakanishi Ryoichi - - 2010
INTRODUCTION: We evaluated the feasibility and safety of the video-assisted thoracic surgery (VATS) lobectomy for non-small cell lung cancer (NSCLC) in patients with comorbidity. METHODS: Between April 2000 and December 2006, a prospective database of 58 consecutive patients undergoing a VATS lobectomy for NSCLC, who had a Charlson comorbidity index ...
Horn D - - 2010
AIM: The aim of the current study was to analyse the results of video assisted thoracoscopic (VATS) talc pleurodesis for malignant pleural effusion. MATERIAL AND METHODS: From January 2002 to December 2004, 50 VATS procedures were performed under general anaesthesia on 48 patients for malignant pleural effusion. There were 45 ...
Yumoto Eiji - - 2010
CONCLUSIONS: A certain degree of subclinical extrathoracic airway compromise may ensue after thyroplastic surgery, although none of the patients reported the presence of dyspneic symptoms in their normal daily lives. OBJECTIVES: To determine the effects of thyroplastic surgery on respiratory function and compare them with the improvement of vocal function. ...
Tong Betty C - - 2010
BACKGROUND: Video-assisted thoracoscopic surgical decortication (VATSD) is widely used for treatment of early empyema and hemothorax, but conversion to open thoracotomy for decortication (OD) is more frequent in the setting of complex, chronic empyema. This study compared indications for and outcomes associated with VATSD and OD. METHODS: The outcomes of ...
Bertolaccini Luca - - 2010
Prolonged postoperative air leaks (AL) are a major cause of morbidity. Aim of this work was evaluating use of a Lung Sealant System (Pleuraseal, Covidien, Mansfield, MA, U.S.A.) in pleural decortications for empyema thoracis. From January 2008 to December 2008, 46 consecutive patients received pleural decortications for empyema thoracis. Post-procedural ...
Jayaraman S - - 2010
A 26-year-old male presented with complaints of dry cough of six months and progressive breathlessness of three months duration. He was coughing out milky white sputum for two months and had lost 12 kg weight in two months. He had an evening rise in temperature of one month duration. Clinically, ...
Assassi Shervin - - 2010
The objective of the present study was to examine the association of baseline demographic and clinical characteristics with sequentially obtained measurements of forced vital capacity (FVC), expressed as a percentage of the predicted value, and to identify predictors of the decline rate in FVC over time in the Genetics versus ...
Karangelis Dimos - - 2010
The aim of the present study was to evaluate the efficacy of autologous blood pleurodesis in the management of persistent air leak in spontaneous pneumothorax. A number of 15 patients (10 male and 5 female) were included in this prospective study between March 2005 and December 2009. The duration of ...
Porfyridis Ilias - - 2010
Differential diagnosis of patients with lung infiltrates remains a challenge. Triggering receptor expressed on myeloid cells (TREM)-1 is a neutrophil and monocyte receptor up-regulated during infection. The aim of this study was to evaluate the diagnostic accuracy of TREM-1 and of C-reactive protein (CRP) from patients with lung infiltrates to ...
VanDevanter Donald R DR Case Western Reserve University School of Medicine, Cleveland, OH, USA. - - 2010
Cystic Fibrosis (CF) is a life-shortening genetic disease in which ~80% of deaths result from loss of lung function linked to inflammation due to chronic bacterial infection (principally Pseudomonas aeruginosa). Pulmonary exacerbations (intermittent episodes during which symptoms of lung infection increase and lung function decreases) can cause substantial resource utilization, ...
Lee Edward Y - - 2010
Purpose: To evaluate initial chest radiographic findings of swine-origin influenza A (S-OIV) (also known as H1N1) viral infection in children. Materials and Methods: This was an institutional review board-approved, HIPAA-compliant retrospective study of 108 patients who had microbiologically confirmed S-OIV infection and available initial chest radiographs obtained between April 2009 ...
Hoksch B - - 2010
BACKGROUND: The thoracoscopic pleurodesis with talc is an established therapy in case of malignant pleural effusion. With the instillation of talc a -localised inflammation is induced. However, some-times it turns into a severe systemic reaction. In this study of the postoperative course, the -question is examined whether a pleural biopsy ...
Tang Yi-Jun - - 2009
BACKGROUND: If the emphysema lesions are not symmetrical, unilateral lung volume reduction surgery (LVRS) can be carried out on the more severe side. The aim of this research was to evaluate the feasibility and effects of LVRS performed simultaneously with resection of pulmonary and esophageal neoplasms. METHODS: Forty-five patients with ...
Marraro Giuseppe A - - 2010
OBJECTIVE: Open lung and low tidal volume ventilation appear to be a promising ventilation for chest trauma as it can reduce ARDS and improve outcome. Local therapy (e.g. BAL) can be synergic to remove from the lung the debris, mitigate inflammatory cascade and avoid damage spreading to not compromised lung ...
Swigris Jeffrey J - - 2010
The response characteristics of the 6 minute walk test (6MWT) in studies of idiopathic pulmonary fibrosis (IPF) are only poorly understood, and the change in walk distance that constitutes the minimum important difference (MID) over time is unknown. To examine changes over time in distance walked (ie, 6MWD) during the ...
Smith John T - - 2009
BACKGROUND: Expansion thoracoplasty using the Vertical Expandable Prosthetic Titanium Rib increases the measured height and volume of the concave hemi thorax, but the effect on the convex, non-instrumented lung is unknown. The purpose of this study was to measure changes in lung volume and density in the convex lung after ...
Oey Inger F - - 2010
Lung volume reduction surgery (LVRS) is conventionally a one-staged bilateral operation. We hypothesised that a more conservative staged bilateral approach determined by the patient not the surgeon would reduce operative risk and prolong the overall benefit. In a population of 114 consecutive patients who were identified as suitable for bilateral ...
Druda D - - 2009
OBJECTIVE: The aims of this study were to compare the estimated size of primary spontaneous pneumothorax (PSP) calculated on inspiratory and expiratory radiographs using the volumetrically derived Collins method and to determine whether radiograph type influences size classification for treatment according to published guidelines. METHOD: This retrospective cohort study included ...
Lonner Baron S - - 2009
STUDY DESIGN: Prospective radiographic and chart review of pulmonary function in patients who underwent 3 different anterior spinal surgery approaches for adolescent idiopathic scoliosis (AIS). OBJECTIVE: To assess the impact on pulmonary function in patients with AIS after anterior surgical approaches, including open thoracotomy, thoracoscopic with and without thoracoplasty, and ...
Snell Gregory I - - 2009
PURPOSE: This study reports the feasibility and safety of novel second-generation bronchoscopic lung volume reduction (LVR) technology, independent of collateral ventilation. DESCRIPTION: Eleven patients with severe heterogeneous emphysema underwent unilateral bronchoscopic application of vapor thermal energy (mean 4.9 cal/g alveolar tissue; range, 3 to 7.5) with bronchial thermal vapor ablation ...
El-Ferzli George T - - 2009
Respiratory failure is a major contributor to mortality and morbidity in newborn infants. The lung assist device (LAD) is a novel gas exchange device that supplements mechanical ventilation. The objective is to test the effect of the LAD on pulmonary histopathology in juvenile piglets with acute lung injury caused by ...
Ueda Kazuhiro - - 2011
We recently introduced a technique of sutureless, mesh-based pneumostasis for preventing alveolar air leaks after lung resection. To verify the clinical usefulness of this technique, we examined if it can contribute to preserving gas exchange capacity and promoting postoperative rehabilitation. We prospectively collected perioperative data, including arterial oxygen saturation on ...
Weng Hao - - 2010
BACKGROUND: In this study, we evaluated the feasibility and accuracy of Univent tube (Fuji Systems, Tokyo, Japan) placement with the aid of auscultation (AUS) or as guided by a lighted stylet (LS) compared with placement guided by the fiberoptic bronchoscope (FOB) or the blind intubation technique as recommended by the ...
Refaely Y - - 2010
This report summarises phase 2 trial results of biologic lung volume reduction (BioLVR) for treatment of advanced homogeneous emphysema. BioLVR therapy was administered bronchoscopically to 25 patients with homogeneous emphysema in an open-labelled study. Eight patients received low dose (LD) treatment with 10 mL per site at eight subsegments; 17 ...
Sterman D H - - 2010
BACKGROUND: Chronic obstructive pulmonary disease (COPD) affects millions of people and has limited treatment options. Surgical treatments for severe COPD with emphysema are effective for highly selected patients. A minimally invasive method for treating emphysema could decrease morbidity and increase acceptance by patients. OBJECTIVE: To study the safety and effectiveness ...
Kobr Jiri - - 2010
The aim of this study was to improve the efficacy of treatment of complicated pleural effusions. In this prospective study, 76 consecutive children (average age 5.0 +/- 4.14 years) fulfilling the required classification criteria were duly treated with chest tube placement and divided into two groups depending on the presence ...
Komori Koji - - 2009
PURPOSE: We evaluated the long-term pulmonary function after lobectomy for congenital cystic lung disease, in both infants and children, using radionuclide imaging (RI). METHODS: We performed a retrospective review of 93 patients who underwent resection of cystic lung lesions between 1974 and 2001. The results of postoperative lung volume/perfusion scintigraphy ...
Farrokhnia E - - 2009
The inflammatory reactions and tissue response after oesophagectomy are leading causes of postoperative morbidity and mortality. We evaluated the effects of intraoperative infusion of prostaglandin E1 (PGE1) on interleukin-6 (IL-6) levels, (A-a) DO2, pulmonary function and complications. This randomised double-blind clinical trial study was performed on patients undergoing transthoracic oesophagectomy ...
Dolecek Martin - - 2009
BACKGROUND/AIMS: Recent studies demonstrated that extravascular lung water (EVLW) is a reliable and independent marker for outcome. The primary therapeutically goal in critically ill patients is to resuscitate and retain adequate organ perfusion by fluid administration, where is necessary to achieve adequate intravascular filling, but avoid initiation of pulmonary edema. ...
Amar David - - 2010
BACKGROUND: There is controversy surrounding the value of the predicted postoperative diffusing capacity of lung for carbon monoxide (DLCOppo) in comparison to the forced expired volume in 1 s for prediction of pulmonary complications (PCs) after thoracic surgery. METHODS: Using a prospective database, we performed an analysis of 956 patients ...
Gelb Arthur F - - 2010
BACKGROUND: This study investigated sites of nitric oxide (NO) gas exchange and response to inhaled corticosteroids (ICS) in patients with COPD and varying extents of emphysema. METHODS: This was a prospective, randomized, single-blind, crossover study in treated, stable, ex-smoking patients with COPD who were ICS and leukotriene receptor antagonists naive. ...
Reck Martin - - 2010
An international expanded access program was initiated to provide access to treatment with pemetrexed prior registration and reimbursement for malignant mesothelioma (MM). Chemonaïve and pretreated patients with inoperable MM of the pleura or peritoneum were eligible. This report describes the results obtained in German centers. Investigators could choose between three ...
Weksler Benny - - 2009
BACKGROUND: Sympathectomy is an effective treatment for hyperhidrosis. The ultrasonic scalpel and electrocautery have been used for the procedure, but the use of the ultrasonic scalpel has been promoted as superior to that of electrocautery. This study explored whether a reusable electrocautery probe was equally as effective and safe as ...
Perkins Jonathan A - - 2009
OBJECTIVE: To describe a method of airway infantile hemangioma staging using standardized assessment of airway narrowing, and hemangioma location and volume, as determined with endoscopy and CT angiography. STUDY DESIGN: Case series with chart review. SETTING: Tertiary pediatric hospital, 2003-2008. SUBJECTS AND METHODS: Subjects included airway hemangioma patients evaluated at ...
Sharma Sangeeta - - 2009
BACKGROUND: A significant proportion of global tuberculosis (TB) caseload is contributed by children. Management of pediatric TB especially EPTB is challenging. The present study was designed to study demographic, clinical profile and treatment outcome of DOTS strategy for pediatric tubercular pleurisy. AIM: To study the efficacy of DOTS strategy. METHODS: ...
Uyama Naoto - - 2009
Glial cytoplasmic inclusions (GCIs) are a pathologic hallmark of multiple system atrophy (MSA), but their pathogenetic roles need to be clarified. To determine possible roles of GCIs in individual cells, serial optical sections obtained by confocal microscopy were reconstructed to yield 3-dimensional (3D) images of the nuclei to quantify nuclear ...
Cobanoglu Ufuk - - 2009
Aim: The study compares the efficiency, side effects and complications of autologous blood pleurodesis with talcum powder and tetracycline. Materials and Methods: This prospective study evaluated 50 patients with persistent air leak resulting from primary and secssondary spontaneous pneumothorax between February 2004 and March 2009. The patients inclussded 32 (64.0%) ...
Freeman Richard K - - 2009
BACKGROUND: Patients with lifestyle-limiting dyspnea attributable to unilateral diaphragm paralysis have been shown to experience a decrease in their dyspnea and an improvement in their pulmonary spirometry and functional status with diaphragm plication acutely after surgery. This investigation summarizes these patients' outcomes with long-term follow-up. METHODS: Adult patients undergoing plication ...
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