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Herth Felix J F - - 2010
Lung volume reduction aims to improve symptoms by reducing hyperinflation. Endoscopic approaches so far have generally been hampered in their efficacy by collateral ventilation (CV). We sought to determine the safety and feasibility of a new endoscopic lung volume reduction approach independent of the effects of CV. Patients with severe ...
Koutroumpas Athanasios - - 2010
This study aimed to assess the effect of mofetil mycophenolate (MMF), an inhibitor of lymphocyte proliferation, on lung function and skin in patients with systemic sclerosis (SSc)-associated interstitial lung disease (SSc-ILD). In this retrospective study, we reviewed the medical files of 10 patients with SSc-ILD (eight females, 10 patients with ...
Allama Amr Mohammad - - 2010
Prolonged air leak is still one of the most frequent complications after pulmonary resections, particularly upper lobectomy. This study aimed at evaluating the efficacy of pleural tenting in decreasing air leak after upper lobectomy. This was a prospective randomised study of 48 patients who had upper lobectomy. They were divided ...
Sustić Alan - - 2010
STUDY OBJECTIVE: To evaluate the role of a brief ultrasound examination (US) in detecting the correct position of the left double-lumen endotracheal tube (LDLT). DESIGN: Prospective, randomized clinical study. SETTING: Operating room of a university hospital. PATIENTS: 50 elective adult thoracic surgery patients who required a LDLT during anesthesia. INTERVENTION ...
Weiss Batia - - 2010
OBJECTIVE: Probiotics reduce intestinal inflammation in, and Lactobacillus GG (LGG) reduces pulmonary exacerbation rate cystic fibrosis (CF) patients. We intended to determine the effect of a mixed probiotic preparation on pulmonary exacerbations and inflammatory characteristics of the sputum in CF patients. STUDY DESIGN: A prospective pilot study of 10 CF ...
Kundra Pankaj - - 2010
This study was designed to compare the effects of preoperative and postoperative incentive spirometry on lung functions after laparoscopic cholecystectomy in 50 otherwise normal healthy adults. Patients were randomized into a control group (group PO, n=25) and a study group (group PR, n=25). Patients in group PR were instructed to ...
Nwogu Chukwumere E - - 2010
BACKGROUND: Although thoracoscopic pneumonectomy may be performed safely, its effect on survival is unknown. METHODS: Seventy patients underwent elective pneumonectomy for malignancy at a comprehensive cancer center (Roswell Park Cancer Institute, Buffalo, NY) from 2002 to 2008. Using the same incision set as thoracoscopic lobectomy, candidates for a thoracoscopic pneumonectomy ...
Sakai R - - 2011
We retrospectively investigated air-leak syndrome (ALS), including pneumothorax and mediastinal/s.c. emphysema, following allogeneic hematopoietic SCT. Eighteen patients (1.2%) developed ALS among 1515 undergoing SCT between 1994 and 2005 at the nine hospitals participating in the Kanto Study Group on Cell Therapy. The median onset of ALS was at 575 days ...
Salunke Pravin Shashikant - - 2011
Parafalcine subdural empyema and those along the superior and inferior surface of the tentorium are rare entities. We present a series of 10 patients where we have attempted to describe the pathophysiology, clinical features, and management of subdural empyema. The study group included 10 cases of falcotentorial subdural empyemas managed ...
Sanders Don B - - 2010
Patients with cystic fibrosis periodically experience pulmonary exacerbations. Previous studies have noted that some patients' lung function (FEV(1)) does not improve with treatment. To determine the proportion of patients treated for a pulmonary exacerbation that does not recover to spirometric baseline, and to identify factors associated with the failure to ...
Hannink Jorien - - 2010
In contrast to the decline in FEV(1), the behavior of dynamic hyperinflation (DH) over time is unknown in patients with COPD. Metronome-paced hyperventilation (MPH) is a simple applicable surrogate for exercise to detect DH. To evaluate changes in MPH-induced DH during two years follow-up in mild-to-severe COPD patients. Additionally, influence ...
Kang Wonseok - - 2010
Bortezomib, an inhibitor of 26S proteosome, is recently approved treatment option for multiple myeloma. Thalidomide, a drug with immunomodulating and antiangiogenic effects, has also shown promise as an effective treatment in multiple myeloma. Pulmonary complications are believed to be rare, especially interstitial lung disease. Here, we describe a patient with ...
Lee Edward Y - - 2010
OBJECTIVE: The purpose of this study was to use paired inspiratory-expiratory volumetric MDCT to compare the frequency, severity, and pattern of air trapping in pediatric patients with tracheomalacia with the findings in children without tracheomalacia. MATERIALS AND METHODS: The study group consisted of 15 consecutively registered pediatric patients (younger than ...
Neligan Patrick J - - 2010
BACKGROUND: Noninvasive positive pressure ventilation (NIPPV) may improve postoperative lung function and reduce postoperative complications in patients undergoing abdominal surgery. The purpose of our study was to determine whether the timing of postoperative NIPPV affects lung function 1 day postoperatively. METHODS: Forty morbidly obese patients with known obstructive sleep apnea ...
Bianchini Maria Anastasia - - 2010
In this paper, we describe our experience in the treatment of childhood empyema using urokinase. Patients' ages ranged from 2 to 12 years. Urokinase (dosage: 3,100 IU/kg/day) was diluted in normal saline to produce 1000 IU/ml (maximum dosage 100,000 IU in 100 ml of normal saline). After 2 hours, the ...
Sakamoto Yuichiro - - 2010
PURPOSE: Atrial natriuretic peptide (ANP) has a variety of pharmacologic effects, including natriuresis, diuresis, vasodilatation, and suppression of the reninangiotensin system. A recent study showed that ANP infusion improved hypoxemia and pulmonary hypertension in a lung injury model. On the other hand, the pulse contour cardiac output (PiCCO(TM)) system (Pulsion ...
Zaman Mumtaz - - 2010
INTRODUCTION: Air trapping because of chronic obstructive pulmonary disease (COPD) leads to a reduction in inspiratory capacity/total lung capacity (IC/TLC) ratio. We hypothesize that COPD patients with a low IC/TLC ratio suffer more frequent COPD exacerbations. METHODS: Retrospective cohort study of patients with COPD, aged 30 years or older with ...
Anraku Masaki - - 2010
BACKGROUND: Conventional mediastinoscopy (CM) is recently being replaced by video-assisted mediastinoscopy (VAM), with potentially better yield and better safety profile for VAM. METHODS: All 645 mediastinoscopies (505 CM, 140 VAM) performed between May 2004 and May 2008 were reviewed. Numbers of stations biopsied, total number of lymph nodes dissected, pathology ...
Saada Julien - - 2010
In utero tracheal occlusion (TO) has been developed to improve the lung hypoplasia associated with congenital diaphragmatic hernia (CDH). However, although TO stimulates fetal lung growth, it results in a decrease of alveolar type II cells (ATII) and surfactant production. Because keratinocyte growth factor (KGF) is a potent stimulus of ...
Gopaldas Raja R - - 2010
Video-assisted thoracoscopic surgery (VATS) is becoming increasingly popular for lung resection in some centers. However, the issue of whether VATS or open thoracotomy is better remains controversial. We compared outcomes of open and VATS lobectomy in a national database. Using the 2004 and 2006 Nationwide Inpatient Sample database, we identified ...
Suehiro Koichi - - 2011
To evaluate the percent change of cerebral oxygen saturation (SctO(2)) during single-lung ventilation (SLV) and its correlation with preoperative respiratory functions. A prospective, observational study. Clinical hospital. Forty patients scheduled for pulmonary lobectomy requiring one-lung ventilation for at least 1 hour under combined epidural/general anesthesia. None. SctO(2) was measured using ...
West Kerry - - 2010
The Acapella is a positive pressure device designed to assist mucociliary clearance. This study investigated the effectiveness of the Acapella in comparison to PEP mask therapy. Twenty-three participants with cystic fibrosis (CF) with a median age of 12 years (range 7-18 years), who were admitted to hospital for a respiratory ...
Burdett Clare L - - 2010
BACKGROUND: Transbronchial biopsy (TBB) is widely used after lung transplant but may not be diagnostic. Our group has used invasive approaches, open lung biopsy (OLB) or video-assisted thoracoscopy (VAT), to establish a definitive diagnosis in unexplained clinical deterioration. We sought to demonstrate the risks and benefits of this approach. METHODS: ...
Inaba Hiroto - - 2010
The number of long-term survivors of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is increasing; however, few studies have addressed their long-term pulmonary function. The authors examined 660 baseline and follow-up pulmonary function tests in 89 long-term survivors of pediatric hematologic malignancies and allo-HSCT. At least 1 abnormal lung parameter was ...
Caglar Meltem - - 2010
BACKGROUND: Estimation of postoperative forced expiratory volume in 1 s (FEV1) with radionuclide lung scintigraphy is frequently used to define functional operability in patients undergoing lung resection. We conducted a study to outline the reliability of planar quantitative lung perfusion scintigraphy (QLPS) with two different processing methods to estimate the ...
Aldrich Thomas K - - 2010
The terrorist attacks on the World Trade Center on September 11, 2001, exposed thousands of Fire Department of New York City (FDNY) rescue workers to dust, leading to substantial declines in lung function in the first year. We sought to determine the longer-term effects of exposure. Using linear mixed models, ...
Licht Peter B - - 2010
BACKGROUND: Endoscopic thoracic sympathicotomy (ETS) is a well-established treatment for primary hyperhidrosis and facial blushing. Not everyone has the desired local effect either from primary failure of the operation or because symptoms recurred. The incidence varies in the literature and treatment by resympathicotomy (re-ETS) is controversial. There is no information ...
Kim Victor - - 2010
BACKGROUND: Poorly reversible airflow obstruction is a hallmark feature of chronic obstructive pulmonary disease (COPD). However, some COPD patients demonstrate significant bronchodilator reversibility (BDR). The pathologic features associated with the presence or absence of this phenomenon are not known. METHODS: We analyzed 67 patients with advanced upper lobe predominant emphysema ...
Park Joon Suk - - 2010
INTRODUCTION: The aim of this study is to compare the outcomes of sleeve lobectomy (SL) and pneumonectomy (PN) and to determine which one is more acceptable standard procedure for patients with non-small cell lung cancer. METHODS: From 1996 to 2005, 424 patients underwent SL (n = 157) and PN (n ...
Mourissoux Gaëlle - - 2010
PURPOSE: This retrospective study was performed in order to determine if patients with very severe chronic obstructive pulmonary disease (COPD) have larger main bronchi than patients with less severe disease. METHODS: Charts of patients having had a spirometric evaluation of their COPD and a digitized thin-slice computed tomography (CT) scan ...
Koç Togay - - 2010
A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed whether insertion of an intercostal chest drain prolongs the length of stay of patients undergoing lung biopsy. Altogether 210 papers were found using the reported search, of which 10 represented the best evidence ...
Carretta Angelo - - 2010
The presence of emphysema may lead to an underestimation of postoperative respiratory function after lobectomy when evaluated by standard functional assessment. The aim of the study was to assess the correlation between computed tomography (CT) densitometry, pathological grading of emphysema and variation of pulmonary function after lobectomy for lung cancer. ...
Boothe Harry W - - 2010
OBJECTIVE-To determine the effect of treatment approach on outcome and the appropriateness of initial empirical antimicrobial treatment in dogs with pyothorax. DESIGN-Retrospective case series. ANIMALS-46 dogs with pyothorax confirmed by either (n = 15) or both (31) of the following: intracellular bacteria in pleural fluid or tissue (41) and bacteria ...
Morrier Janelle - - 2010
PURPOSE: To evaluate the efficacy of a seed-migration detector and to compare its performance to fluoroscopy and postoperative chest radiographs. METHODS AND MATERIALS: A gamma scintillation survey meter was converted to a seed-migration detector by adding a shield on the probe detection window. The detector response to three (125)I seed ...
Sundararajan L - - 2010
Pulmonary rehabilitation (PR) has been shown to be an effective intervention in the management of patients with chronic obstructive pulmonary disease (COPD), but its role in elderly patients is not clearly defined. We investigated the effectiveness of rehabilitation in elderly patients with COPD. Patients underwent multidisciplinary PR in a hospital ...
Liberman Moishe - - 2010
BACKGROUND: Persistent air leak (PAL; defined as air leak > 5 days) after major pulmonary resection is prevalent and associated with significant morbidity. This study examines an incompletely characterized treatment for the management of PAL, chemical pleurodesis. METHODS: A retrospective case-control study examining all isolated lobectomies and bilobectomies by thoracotomy ...
Kurihara Masatoshi - - 2010
OBJECTIVE: Currently, the treatment of pneumothorax varies among hospitals. Three factors account for the differences. First, pneumothorax expresses the state of disease instead of the disease itself. Some pneumothoraces heal on their own but patients with pneumothorax due to chronic diseases may need further intervention. The decision for the choice ...
Metin M - - 2010
The purpose of this study was to investigate the results of minimally invasive treatment modalities in early stage multiloculated empyema thoracis. The minimally invasive treatment modalities of 114 patients with Class 5 thoracic empyema were retrospectively reviewed. The patients' demographics, symptoms, diagnostic studies, treatment options and complications were evaluated. A ...
Moore Alastair J - - 2010
BACKGROUND: Gas trapping in emphysema results in resting and dynamic hyperinflation. We tested the hypothesis that a direct connection between the lung parenchyma and the atmosphere could increase expiratory flow and thereby potentially improve dyspnea through the relief of gas trapping. METHODS: Ex vivo we studied 7 emphysematous lungs and ...
Sontag Marci K - - 2010
RATIONALE: Airway secretion clearance therapies are a cornerstone of cystic fibrosis care, however longitudinal comparative studies are rare. Our objectives were to compare three therapies [postural drainage and percussion: (postural drainage), flutter device (FD), and high frequency chest wall oscillation: (vest)], by studying (1) change in pulmonary function; (2) time ...
Colaci M - - 2010
OBJECTIVES: Systemic sclerosis (SSc) is characterized by abnormal fibrosis of the skin and internal organs, particularly the lungs. Recent reports have revealed a lack of correlation between bronchoalveolar lavage (BAL) variations and response to cyclophosphamide (CYC) in patients with scleroderma-related alveolitis. Our study aimed to evaluate whether the normalization of ...
Refai Majed - - 2010
The objective of this investigation was to compare postoperative morbidity and early and late mortality in patients after pneumonectomy for non-small-cell lung cancer (NSCLC) with or without induction neo-adjuvant therapy. This is an observational study performed on prospectively collected data at four tertiary referral centres (2000-2007). Of 225 pneumonectomies for ...
Ahmad Tanveer - - 2010
OBJECTIVE: To compare the clinical presentation and results of pulmonary resection in simple and complex aspergilloma of the lung. STUDY DESIGN: Observational study. PLACE AND DURATION OF STUDY: The Department of Thoracic Surgery, Jinnah Postgraduate Medical Centre, Karachi, from January 2003 to December 2008. METHODOLOGY: Fifty-one adult patients with unilateral ...
Oliveira Juliana F - - 2010
Tuberculosis (TB) remains as an important public health problem worldwide. The most common type is pulmonary TB, and the most prevalent form of extra-pulmonary disease among HIV-negative patients is pleural disease. The objective of the present study was to determine the effect of continuous positive airway pressure (CPAP) on fluid ...
Rea Harold - - 2010
AIM: Persistent airway inflammation with mucus retention in patients with chronic airway disorders such as COPD and bronchiectasis may lead to frequent exacerbations, reduced lung function and poor quality of life. This study investigates if long-term humidification therapy with high flow fully humidified air at 37 degrees C through nasal ...
Reeve Julie C - - 2010
This study investigates whether targeted postoperative respiratory physiotherapy decreased the incidence of postoperative pulmonary complications and length of stay for patients undergoing elective pulmonary resection via open thoracotomy. Seventy-six patients participated in a prospective, single-blind, parallel-group, randomised trial with concealed allocation, assessor blinding and intention-to-treat analysis. Treatment group participants received ...
Komasawa Nobuyasu - - 2010
To compare tracheal intubation with the Pentax Airway Scope (AWS) and the Macintosh laryngoscope (McL) during chest compression, 25 anesthesiologists (including 12 specialists having >5 years of experience and 13 trainees having <2 years of experience) performed tracheal intubation using either the McL or the AWS, with or without chest ...
Nakanishi Kozo - - 2010
Fibrin glues are widely used for various pulmonary operations, but commercially produced glues are made of heterogeneous fibrinogen that has infection risks. We used autologous cryoprecipitate and evaluated its clinical value as a fibrin sealant instead of the commercially available glue. One hundred patients who underwent thoracoscopic bullectomy for primary ...
Dey A - - 2010
INTRODUCTION: The management of recurrent pleural effusion or pneumothorax has always been a cause for serious concern among chest physicians. Among the wide variety of agents that are available for pleurodesis, povidone iodine is now perhaps the most sought after agent as it is cheap, easily available, effective and safe. ...
Suehiro Koichi - - 2010
To examine perioperative management and complications in patients undergoing pneumonectomy. Observational cohort study. University-affiliated city hospital. 65 patients who underwent unilateral pneumonectomy for resection of lung cancer between March 1997 and October 2007 were included in this study. Patients who underwent pneumonectomy were then classified into two groups: Group C ...
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