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Jungersted Jakob Mutanu - - 2010
Alitretinoin is a new drug for systemic treatment of chronic hand eczema. Previous functional tests of skin topically treated with retinoids have indicated impaired skin barrier function, but no data are available on barrier parameters after systemic alitretinoin treatment. To investigate the effect of systemic alitretinoin on skin barrier function ...
Hunter Nahla - - 2011
To evaluate the efficacy of two topically applied immunomodulative agents through the detection of lymphocyte subsets using monoclonal antibodies against CD4, CD8 and MHC II. Fifty patients from the Departments of Medical Biochemistry, Dermatology and Pathology at Cairo University with different degrees of alopecia areata (AA) were included in this ...
Kulick Michael I - - 2010
Cellulite is a condition usually limited to women. The most common location for this surface irregularity is the thigh. Evaluation of treatment efficacy is difficult because of the reliance on patient satisfaction surveys and flash photography, which can "flatten" surface texture. Reproducibility of photographs is also difficult, as subtle changes ...
Willey Andrea - - 2010
The healing process of a novel radiofrequency bipolar system was recently shown to produce a profound increase in collagen and elastin content. To determine the relationship between subjective clinical improvement scores and changes in objective measures of mechanical skin properties. Elastometry measurements were made at baseline and 3 months after ...
Li Dong-Ni - - 2010
BACKGROUND AND OBJECTIVE: The treatment of infantile hemangioma must address both the effectiveness of the treatment and have as few adverse events as possible for the patient as a result of the therapy. The intense pulsed light (IPL) source can be useful in this regard in treating infantile hemangioma. IPL ...
Musarra A - - 2010
BACKGROUND: The clinical efficacy of Monophosphoryl lipid A-adjuvanted immunotherapy (MPLA-SCIT) is ascertained, but there are no data on its possible long-lasting effect. We assessed in a real-life setting the persistence of the clinical effect five years after discontinuation. METHODS: Patients with parietaria-induced respiratory allergy and fulfilling the criteria for immunotherapy ...
Polnikorn Niwat - - 2010
OBJECTIVE: To evaluate the effectiveness of a Q-switched Nd:YAG laser (MedLite C6; HOYA ConBio, Fremont, CA, USA) and 7% alpha arbutin solution (Skin Advance Laboratory, Japan) in the treatment of melasma. METHODS: This was a prospective study of 35 refractory melasma cases treated with 10 weekly laser sessions, two monthly ...
Ge Liangpeng - - 2010
It is widely recognised that take of grafts is strongly influenced by tissue viability. Although porcine skin is currently the most widely used xenograft, the viability change of pigskin in vitro has not been extensively studied. The purpose of this study was to assess the change of the viability of ...
Dedola Carla - - 2010
Skin biopsies from five Border terriers with histologically confirmed idiopathic, generalized sebaceous gland hyperplasia (Group A) were compared morphometrically to those from four unaffected Border terriers (Group B) and the unaffected dogs to biopsies from four other terrier breeds (Group C). Dogs in Group A had significantly higher numbers of ...
Gäddnäs Fiia P - - 2010
BACKGROUND: Skin is an essential barrier in maintaining a stable internal environment. Adequate regenerative capacity is crucial to overcome the homeostatic challenges caused by a septic insult. In sepsis, coagulation and inflammation are activated to restore homeostasis, but it is not known whether sepsis also alters tissue regeneration processes such ...
Militão de Sousa F - - 2010
Synopsis To evaluate the efficiency and safety of a new galenic meta-emulsion for the treatment of human head lice (Pediculus capitis) in a single application. A controlled clinical study was conducted comparing lice infestation and nit hatching observed before and after a treatment in a single application. Eighty-two of the ...
Kütting Birgitta - - 2010
BACKGROUND: Measurements of transepidermal water loss (TEWL) as an indicator of skin barrier function and colorimetry for quantifying erythema have been recommended for monitoring persons at risk of occupational hand dermatitis. OBJECTIVE: This study examines the practicability and usefulness of biophysical measurements at the workplace. PATIENTS/MATERIAL/METHODS: A sample of 1020 ...
Gupta Monique - - 2010
To characterize the clinical changes in clinically distinctive scalp nevi over time in children to help guide management and avoid misdiagnosis as melanoma. Cohort study. Washington University School of Medicine pediatric dermatology clinics. Patients Of 93 patients younger than 18 years with photographically documented, clinically distinctive scalp nevi, 28 (30%) ...
Fatemi Afschin - - 2010
Currently available technologies for performing aesthetic body sculpting are either noninvasive but require multiple treatments to achieve relatively superficial effects or very effective but also invasive and sometimes associated with serious complications. A new, noninvasive alternative is to ablate adipose tissue using high-intensity focused ultrasound (HIFU). When focused within subcutaneous ...
Yoo Kwang Ho - - 2010
BACKGROUND: Photodynamic therapy (PDT) with aminolevulinic acid or methyl 5-aminolevulinic acid (MAL) has been tried for the treatment of alopecia areata (AA). Unfortunately, the efficacy of PDT in treating AA is still being debated, and most clinical trials have produced disappointing results, which may have been because of the lack ...
Kotlus Brett S - - 2010
BACKGROUND: Laxity and rhytidosis of eyelid skin as a result of photoaging is a frequent cosmetic concern. Fine lines and deep wrinkles may not be optimally addressed with traditional ablative carbon dioxide (CO(2)) resurfacing. Modern devices allow for surface fractional ablation and deep fractional ablation with narrow treatment columns that ...
Yotsawimonwat S - - 2010
Synopsis Echinacea purpurea contains many beneficial constituents for protection of skin from oxidative stress and for improving hydration of skin. This study aimed to investigate the stability and dermatological efficacy of E. purpurea cream and gel. Echinacea purpurea extract was incorporated into suitable cream and gel bases. Stability of the ...
D'Anneo R W - - 2010
Sublingual immunotherapy with monomeric allergoid (allergoid SLIT), given according to the standard scheme, has proved effective and safe in many clinical trials. However, its build-up phase requires a long time ranging from 16 days to 14 weeks. This study therefore investigated whether, with a four-day up-dosing, the same benefit could ...
Murthy P S - - 2010
A 51-year-old circumcised male presented with hard, thick, keratotic, nail-like covering of the skin of his glans penis of 2 year duration. Histology showed acanthosis, papillomatosis, and elongated rete ridges into the dermis suggestive of pseudoepitheliomatous, keratotic, and micaceous balanitis with features of cellular atypia. Partial penile amputation was done. ...
Das Sudip - - 2010
There have been various controversial reports regarding the efficacy of topical agents in topical therapy of alopecia areata. The study aims to find out the effective ones among the readily available ones for a dermatologist. Eighty patients were chosen from the skin OPD of Bankura Sammilani Medical College, Bankura, West ...
Zoccali Giovanni - - 2010
Hypermelanosis includes a diverse group of genetic and acquired skin anomalies that appear as darker, hyperpigmented areas. Melasma, in particular, is a hypermelanotic condition that affects sun-exposed skin in females. Whether this condition is acquired or genetic is still controversial. However, it clearly correlates with exposure to UV light, a ...
Aust M C - - 2010
Photoageing is generally treated by ablative procedures that injure the epidermis and basement membrane, and lead to fibrosis of the dermis. Percutaneous collagen induction (PCI) therapy is an alternative treatment for photoaged skin that does not result in clinical signs of dermal fibrosis. In this study, the immediate effects of ...
Ascher Benjamin - - 2010
BACKGROUND: The UltraShape Contour I System (CE 0344; UltraShape Ltd., Yoqneam, Israel) is a noninvasive fat reduction and body contouring system currently approved for use outside the United States that utilizes focused ultrasound to selectively disrupt adipocytes. OBJECTIVE: To evaluate the clinical safety and efficacy of the Contour I system ...
Guiotti Aimée Maria - - 2010
The failure of facial prostheses is caused by limitations in the properties of existing materials, especially flexibility and durability. Therefore, this study evaluated the Shore A hardness of silicone used for fabrication of facial prostheses, Silastic MDX4-4210, according to the influence of storage period, daily disinfection, and 2 types of ...
Lacouture Mario E - - 2010
PURPOSE: Panitumumab, a fully human monoclonal antibody targeting the epidermal growth factor receptor (EGFR), is approved in the United States and Europe for the treatment of refractory metastatic colorectal cancer (mCRC). Skin toxicities are the most common adverse events with EGFR inhibitors. This is the first study designed to examine ...
Alam Murad - - 2010
BACKGROUND: Nonablative skin tightening technologies offer the prospect of reduction of wrinkles and skin sagging with minimal downtime, discomfort, and risk of adverse events. The excellent safety profile is mitigated by the limited efficacy of such procedures. OBJECTIVE: We sought to assess the efficacy of ultrasound skin tightening for brow-lift ...
Gold Michael H - - 2010
Low-energy intense pulsed light for hair removal at home was evaluated in this clinical trial. Twenty-two female patients were enrolled into an institutional review board-approved clinical trial. Patients received six biweekly treatments with the device, and clinical results with hair counts and pictures were performed at four weeks and three ...
Atkin Deborah H - - 2010
A 3-month, open-label, single-center study was conducted to determine whether a uniquely formulated and physiologically balanced topical treatment serum containing multiple growth factors, cytokines, peptides, antioxidants and depigmenting agents could improve the visible signs of facial photodamage. Thirty-seven females, aged 32-55 years, with mild to severe, fine and coarse peri-ocular ...
Nymann P - - 2010
OBJECTIVE: This study aims to compare the efficacy and adverse effects of long-pulsed dye laser (LPDL) and intense pulsed light (IPL) in the treatment of facial telangiectasias. METHODS: We used intra-individual, randomized, controlled trial with split-face treatments and single-blind outcome evaluations in this study. Forty patients with symmetrically located facial ...
Li Yuan-Hong - - 2010
BACKGROUND AND OBJECTIVES: Intense pulsed light (IPL) is regarded as the gold standard of nonablative photo-rejuvenation. Yet there is still a need to observe its efficacy and safety on dark skin using a split-face module. STUDY DESIGN/MATERIALS AND METHODS: Twenty-four Chinese women with photoaging were enrolled in this study. Patients ...
Chang S-S - - 2010
AIM: To investigate the efficacy of steam pasteurization for reducing Salmonella serotype Enteritidis on raw almond surfaces. METHODS AND RESULTS: Nonpareil almonds were inoculated to 10(7-8) CFU g(-1) with a Salm. Enteritidis cocktail (Salm. Enteritidis 43353, ME-13, ME-14) or Salm. Enteritidis phage type 30, dried overnight and subjected to steam ...
Zucchi Alessandro - - 2010
PURPOSE: We present a new, 2-stage functional and cosmetic reconstruction of concealed penis in adults with short-term subjective outcomes. MATERIALS AND METHODS: Patients with excess penile skin removal, shaft tissue scarring and penile retraction with poor functional and cosmetic results underwent 2-stage repair. At stage 1 after a coronal incision ...
Goldman Mitchel P - - 2010
PURPOSE: To determine the efficacy of a skin care system developed with a partially neutralized glycolic compound and natural antioxidants when compared to Cetaphil moisturizing regimen for the treatment of photoaging of the face, eye and mouth. METHODS: A total of 36 patients between 35 and 65 years of age ...
Reuther Tilmann - - 2010
The purpose of this study was to evaluate in vivo the effects of micropuncture injections of stabilized hyaluronic acid-based gel of non-animal origin (NASHATM, Restylane Vital) on skin elasticity, a major aspect of skin ageing. Patients (n = 19) underwent a series of three treatment sessions, spaced 4 weeks apart, ...
Pabon Diego F - - 2010
Skin flora immobilization technology is similar in efficacy to Iodine-Povidone in healthy volunteers. We did a prospective study in a university clinic with 60 healthy volunteers. Right inguinal skin area on healthy volunteers was used to compare the antimicrobial properties of cyanoacrylate sealant (FloraSeal, Adhesion Biomedical, Wyomissing, PA) versus standard ...
Sakçak Ibrahim - - 2010
Many conservative methods have been applied in the treatment of pilonidal sinus disease (PSD). The most commonly used conservative treatment is 80% phenol solution. Our observations demonstrated that 80% phenol solution caused much destruction in the sacrococcygeal region. In this study low concentrations of phenol were used with the aim ...
Alomari Qasem - - 2010
AIM: The study aimed to evaluate the effect of four in-office dental bleaching methods on shade change, color stability, patient satisfaction and postoperative sensitivity. METHODS AND MATERIALS: Forty patients were randomly divided into four groups (n=10) according to the method of in-office bleaching used: Group A-35% hydrogen peroxide (HP); Group ...
Răducanu Anca Maria - - 2010
This clinical report describes the oral rehabilitation of a 7-year-old male diagnosed with hypohidrotic ectodermal dysplasia and anodontia. Ectodermal dysplasia (ED) comprises a large, heterogeneous group of inherited disorders, which are defined by primary defects in the development of two or more tissues derived from the embryonic ectoderm (skin, hair ...
Papadopoulos E - - 2010
An in vitro assay was used to assess the efficacy of the proprietary pyrethroid insecticide cypermethrin applied to horses (Deosect spray, 5.0%, w/v Fort Dodge Animal Health) against the biting midge Culicoides nubeculosus (Meigen) (Diptera: Ceratopogonidae) and the mosquitoes Aedes aegypti Linneaus and Culex quinquefasciatus Say (Diptera: Culicidae). Hair was ...
Haslik W - - 2010
The treatment of deep dermal burns has a broad spectrum and has been subject to discussion over the past years. The treatment of hand burns is challenging due to the high requirements to aesthetic and functional outcome. 27 patients, 7 women and 20 men with deep dermal hand burns with ...
Coronel-Pérez I M - - 2010
OBJECTIVES: The aim of this study was to test the efficacy of latanoprost in eyelash alopecia areata (AA). DESIGN: This study is a 2-year prospective, non-blinded, non-randomized, bilateral eyelash alopecia controlled study. SETTING: The setting of this study was Trichology Unit, Virgen Macarena University Hospital, Seville, Spain. PATIENTS: We conducted ...
Kautz Gerd - - 2010
The blanching of resistant port wine stains (PWS) with a pulsed dye laser (PDL) requires a large number of treatments, resulting in substantial discomfort to patients, many of them children. Pneumatic skin flattening (PSF - Serenity Pro) is a new technology that generates a vacuum over the skin and reduces ...
Choi Y S - - 2010
BACKGROUND: Various laser and light therapy have been increasingly used for the treatment of acne vulgaris. PATIENTS AND METHODS: Twenty patients with facial acne were treated using intense pulsed light (IPL) on one side of the face and pulsed dye laser (PDL) on the other to compare the efficacy and ...
Issa Maria Cl?udia Almeida - - 2010
BACKGROUND: Photodynamic therapy (PDT) is an option for skin rejuvenation. Although many studies report clinical improvement with PDT in photodamaged skin, histologic and morphometric evidence is not documented in most cases. OBJECTIVE: To evaluate clinical and histopathologic changes induced by methyl aminolevulinate (MAL)-PDT and to morphometrically quantify collagen and elastic ...
Weyandt Gerhard H - - 2009
BACKGROUND: Split-skin grafting is a routine reconstructive technique associated with large variation in practice. Grafts from the thigh, buttock, or abdomen take a long time to heal and may leave unpleasant, hypopigmented scars. Retrospective reports favor the scalp as a donor site in burn patients. OBJECTIVE: Evaluation of duration of ...
Gupta Michael - - 2009
The objective of this study was to significantly reduce the donor site morbidity associated with use of the radial forearm free flap (RFFF). A pilot study to test the feasibility of topical tissue expanders to close the RFFF donor site. The setting was a tertiary care teaching hospital. This pilot ...
Shamban Ava T - - 2009
Patients with photodamaged skin need guidance in selecting treatment plans that optimize outcomes, minimize downtime, and reduce adverse effects. The gold standard among cosmeceuticals is the topical retinoids, such as tretinoin. A topical formulation of folic acid and creatine appears to be a viable treatment option for the treatment of ...
Bhawan Jag - - 2009
Melasma is a common disorder affecting a significant percentage of the population, particularly those with skin of color. Therapy with hydroquinone, a depigmenting agent, as a single agent or in combination with other agents has been used with variable success. A triple-combination (TC) cream combining hydroquinone 4% with tretinoin 0.05% ...
Freedman Bruce M - - 2009
BACKGROUND: There has been great interest in improving the efficacy of nonablative technologies by combining them during facial skin rejuvenation. The purpose of this study was to determine whether the addition of topical polyphenolic antioxidants to an intense pulsed light (IPL) treatment regimen augmented the effects of facial IPL treatments. ...
Brightman Lori - - 2009
BACKGROUND AND OBJECTIVES: Skin laxity of the body is a growing cosmetic concern. Laxity can result from chronological or photoaging and changes in body dimensions during pregnancy or weight loss. The end result is loose, sagging skin, and localized fat deposits. Liposuction and abdominoplasty or brachioplasty are established approaches to ...
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