Search Results
Results 1 - 50 of 2897
1 2 3 4 5 6 7 8 9 10 >
Tanus Tonny T Tonny Tanus, MD, is Director, Kern Allergy Medical Clinic Inc, Bakersfield, California, and Assistant Clinical Professor, David Geffen School of Medicine, University of California, Los Angeles. Nicole E. Scangarella-Oman, MS, is an Investigator; Marybeth Dalessandro, BS, is Manager, Clinical Development; Gang Li, PhD, is Manager, Statistics; John J. Breton, MCM, is Manager, Clinical Development; and John F. Tomayko, MD, is Senior Director, all in the Department of Infectious Diseases Medicines Discovery and Development, GlaxoSmithKline, Collegeville, Pennsylvania. The authors disclose they will discuss off-label uses of retapamulin 1% (Altabax, Altargo). Dr Tanus has disclosed that he is/was a recipient of grant/research funding from Stiefel/GlaxoSmithKline, Amgen, and Genentech; he is a recipient of grant/research funding from Teva Pharmaceuticals; and he was a member of the speakers' bureau for Astra Zeneca. The coauthors have disclosed they are employees of GlaxoSmithKline. Ms Scangarella-Oman, Ms Dalessandro, Mr Breton, and Dr Tomayko have disclosed they are stock shareholders of GlaxoSmithKline. The authors disclose that the study was supported by funding from - - 2014
To evaluate the clinical and bacteriological efficacy of topical retapamulin ointment 1% versus oral linezolid in the treatment of patients with secondarily infected traumatic lesions (SITLs; excluding abscesses) or impetigo due to methicillin-resistant Staphylococcus aureus (MRSA). A randomized, double-blind, double-dummy, multicenter, comparative study (NCT00852540). Patients recruited from 36 study centers ...
Faulde Michael K MK Department of Medical Entomology / Zoology, Central Institute of the Bundeswehr Medical Service, PO box 7340, 56065, Koblenz, Germany, - - 2014
The protective effectiveness of factory-based permethrin-impregnated polymer-coated battle dress uniforms (PTBDUs) against tick bites was evaluated at four military training areas in southwestern and central Germany where tick bite incidence is known to be high. Data were analyzed by comparing tick bite incidence using non-permethrin-treated BDUs (NTBDUs) during 2009 versus ...
Wengenmayer Christina - - 2014
BackgroundPathogens that are transmitted by ticks to dogs, such as Anaplasma phagocytophilum, Babesia spp., Borrelia burgdorferi sensu latu, and Ehrlichia canis, are an increasing problem in the world. One method to prevent pathogen transmission to dogs is to kill the ticks before transmission occurs. Fluralaner (BravectoTM) is a novel isoxazoline ...
Zechner G G Elanco Animal Health, Kölblgasse 8-10, Vienna, - - 2014
A blinded, controlled, randomised field study was undertaken on two commercial dairy farms in Germany to compare the efficacy of the anticoccidials, diclazuril and toltrazuril in the prevention of bovine coccidiosis. A total of 86 calves aged between five and six weeks were randomly allocated to two treatment and one ...
Erdem Elif E Department of Ophthalmology, Faculty of Medicine, University of Çukurova, Adana, - - 2014
Here, we describe a case of keratitis caused by Aspergillus terreus in an 80-year-old immunocompetent woman 1 month after uneventful cataract surgery. The patient presented with decreased visual acuity (20/50) and severe pain in her right eye. Examination revealed a 3.5 × 4.5 mm white-colored deep stromal infiltration located on the temporal corneal tunnel ...
Kovachev Stefan Miladinov SM Department of Gynecology, Military Medical Academy, G. Sofijsky Str. 3, 1600, Sofia, Bulgaria, - - 2014
The high rate of vaginal Candida albicans recurrence is attributed to azole resistance rates as high as 15 %. The aim of this study was to determine the clinical and microbiological efficacy of standard azole therapy for treatment of vaginal C. albicans infection alone and in combination with local probiotic as ...
Del Piano Mario M *Gastroenterology Unit, Maggiore della Carità Hospital †Biolab Research Ltd., Novara, - - 2014
The inhibition of physiological gastric acid secretion induced by proton pump inhibitors (PPIs), the most widely used drugs in the world, may cause a significant bacterial overgrowth in the gastrointestinal tract as a side effect. This study was undertaken firstly to correlate PPI intake with concentration of specific bacterial groups ...
Fazzio L E LE Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, 60 y 118, 1900 La Plata, Argentina. Electronic address: - - 2014
The aim of this study was to evaluate, in a commercial feedlot, the effect of different anthelmintic drugs on the productivity of naturally infected calves from a cow-calf operation, where resistance to ivermectin (IVM) has been previously detected. The study began with the random selection of 80 calves whose weight ...
Philippe P P Elanco Animal Health, 24 Boulevard Vital Bouhot, 92521 Neuilly sur seine, France. Electronic address: - - 2014
A blinded, randomized, controlled, multi-centric field study was conducted on French dairy farms (n=9) to evaluate the long term efficacy of metaphylactic, single oral treatments with either 1mg/kg body weight (BW) of diclazuril (Vecoxan(®)), or 15mg/kg BW of toltrazuril (Baycox(®)) against natural infections with Eimeria zuernii and/or Eimeria bovis, compared ...
Bumpass J Brock JB Global Medical Affairs Department, Cubist Pharmaceuticals, Lexington, Massachusetts Massachusetts College of Pharmacy and Health Sciences, - - 2014
We conducted a survey to compare antimicrobial stewardship outcomes considered to be most important with those used in practice as metrics. Respondent opinion of important outcomes compared with those collected as metrics were antimicrobial use (15% vs 73%), antimicrobial cost (10% vs 73%), appropriateness of antimicrobial use (56% vs 51%), ...
Sun Zhenhui Z Center for Joint Disease, Chonnam National University Hwasun Hospital, Gwangju, South - - 2014
Controversies exist regarding the ideal approach in a revision total knee arthroplasty for infection, providing adequate exposure with minimum complications. The purpose of this study was to compare the results of second stage revision total knee arthroplasty (TKA) between tibial tubercle osteotomy (TTO) and quadriceps snip (QS) approaches for infected ...
Wilder Kerry A KA Neonatal Intensive Care Unit, Children's Medical Center Dallas, - - 2014
Peripheral intravenous (PIV) infiltrations causing tissue damage is a global issue surrounded by situations that make vascular access decisions difficult. The purpose of this quality improvement project was to develop an algorithm and assess its effectiveness in reducing PIV infiltrations in neonates. The targeted subjects were all infants in our ...
Lewin Richard R From the Department of Plastic and Hand Surgery, Institute of Clinical Sciences, University of Göteborg, Sahlgrenska Academy, Sahlgrenska University Hospital, Göteborg, - - 2014
Postoperative infection after breast reduction surgery is a common complication, with the most commonly involved pathogen being Staphylococcus aureus. Previous studies of antibiotic prophylaxis in breast reduction surgery have been inconclusive. The aim of the present study was to clarify the role of prophylactic antibiotics in breast reduction surgery. In ...
Morton John M JM Jemora Pty Ltd., PO Box 2277, Geelong, Victoria 3220, Australia. Electronic address: - - 2014
A controlled trial was conducted in 5 pasture-grazed commercial dairy herds in Australia in 2012 to determine whether premilking teat disinfection and drying of teats reduces clinical mastitis incidence during early lactation by at least 50%. A 50% reduction was estimated to be the minimum required to justify additional costs ...
Chahed Jamila J Department of Pediatric Surgery, EPS Fattouma Bouguiba, Faculty of Medicine, Monastir, CP 5000, - - 2014
Wound infection is the most frequent complication in burn patients. There is a lack of guidelines on the use of systemic antibiotics in children to prevent this complication. A prospective study is carried out on 80 patients to evaluate the role of antibiotic prophylaxis in the control of infections. The ...
Leta Tesfaye H TH The Norwegian Arthroplasty Register, Department of Orthopedic - - 2014
Background and purpose - In Norway, the proportion of revision knee arthroplasties increased from 6.9% in 1994 to 8.5% in 2011. However, there is limited information on the epidemiology and causes of subsequent failure of revision knee arthroplasty. We therefore studied survival rate and determined the modes of failure of ...
Halos Lénaïg - - 2014
Ticks are hematophageous arthropods that transmit a wide spectrum of pathogens to human and animals. The ability of an acaricidal product to kill ticks quickly provides an important added benefit, especially as protecting dogs from tick bites remains the best preventive measure against tick-borne diseases. The speed of kill of ...
Ravi Bheeshma B Division of Orthopaedic Surgery, Department of Surgery, University of Toronto, Toronto, - - 2014
Objective Therapeutic intra-articular injections are used in the management of hip osteoarthritis (OA). Some studies suggest their use increases risk for infection, and thus revision, after THA, while others do not. We sought to clarify the relationship between prior intra-articular injection and the risk of complication in a subsequent total ...
McCall John W JW TRS Labs Inc., 215 Paradise Blvd., Athens, GA 30607, United States. Electronic address: - - 2014
A controlled laboratory study was conducted to establish the safety and efficacy of 10% imidacloprid+2.5% moxidectin topical solution (Advantage Multi(®) for Dogs, Bayer HealthCare, Shawnee, KS) for the treatment of circulating Dirofilaria immitis microfilariae in dogs. Twenty beagles were experimentally infected with D. immitis via surgical implantation of 10 pairs ...
Arteagoitia Iciar I Stomatology I Department, Research group UPV/EHU IT821-13, University of the Basque Country, Leioa, Bizkaia, - - 2014
The purpose of this study was to determine the effect of amoxicillin/clavulanic acid to prevent infection following completely bone-impacted lower third molar removal. A random, double-blind placebo-controlled clinical trial including 118 adults randomly allocated to placebo (60 patients) or antibiotic treatment (58 patients): 2 g amoxicillin/125 mg clavulanic acid 2 hours before the ...
Toltzis Philip P Rainbow Babies and Children's Hospital, Cleveland, Ohio; - - 2014
Surgical site infections (SSIs) are preventable events associated with significant morbidity and cost. Few interventions have been tested to reduce SSIs in children. A quality improvement collaboration was established in Ohio composed of all referral children's hospitals. Collaborative leaders developed an SSI reduction bundle for selected cardiac, orthopedic, and neurologic ...
Carretón E E Faculty of Veterinary Medicine, University of Las Palmas de Gran Canaria, Las Palmas, Spain. Electronic address: - - 2014
Adulticide treatment of dogs with canine heartworm disease causes the death of the adult Dirofilaria immitis lodged in the vascular system of the host. During the death of the worms, pulmonary thromboembolisms (PTE), pulmonary inflammation, congestive heart failure, or renal disease are possible consequences. The aim of this study was ...
Sehgal Inderpaul Singh IS Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, - - 2014
The aim of this study was to evaluate the efficacy of Mycobacterium w (Mw), an immunomodulator in severe sepsis. Patients 18 years or older with severe sepsis were randomized within 48 hours of first organ dysfunction to receive either intradermal Mw or saline. The primary end point was 28-day mortality, ...
Liu Hao H School of Environmental and Civil Engineering, Jiangnan University, Wuxi 214122, - - 2014
Reductive removal of nitrate in bioelectrochemical system (BES) at abiotic cathode, biocathode and biohydrogen facilitated biocathode were investigated. It was found that nitrate removal efficiency reached 95% and 59% at the biohydrogen facilitated biocathode and biocathode respectively, while which was only 13% at the abiotic cathode. Meanwhile, activity of nitrate ...
Wilford Sophie S Department of Clinical Science and Services, Equine Referral Hospital (Wilford, Dunkel), and Final Year Veterinary Student (Woodward), The Royal Veterinary College, North Mymms, Herts AL9 7TA, United - - 2014
A retrospective questionnaire-based survey was used to determine the perceived efficacy of Newmarket bloodroot ointment in treating equine sarcoids. In 49 horses with 74 sarcoids, 64 sarcoids responded either completely (n = 49) or partially (n = 15) while 10 did not respond or worsened. Sarcoids < 2 cm responded ...
Kirsch Andrew J AJ Department of Pediatric Urology, Children's Healthcare of Atlanta and Emory University School of Medicine, Atlanta, GA. Electronic address: - - 2014
To determine the current preferred injection technique(s) for endoscopic management of pediatric vesicoureteral reflux (VUR). Since the approval of dextranomer hyaluronic acid copolymer (Dx/HA) in 2001, injection methods have evolved and now include the hydrodistention implantation technique (HIT) and double HIT as well as subureteral transurethral injection (STING) method. In ...
Sainsbury David C G DC Division of Plastic and Reconstructive Surgery, The Hospital for Sick Children, and University of Toronto, Toronto, Ontario, - - 2014
Limb salvage operations in patients with bony oncologic defects carry technical challenges and may require long recoveries. This study aimed to evaluate functional outcomes, donor site morbidity, and complications in lower limb defects reconstructed with vascularized fibula flaps in children. We performed a retrospective review and telephone survey of consecutive ...
Graves Christopher M CM Department of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, - - 2014
We evaluated 459 patients undergoing THA or TKA who completed preoperative and postoperative WOMAC and/or SF36 surveys. Medical comorbidities and reported allergies were also recorded. Evaluation of surveys was compared for patients with or without 4 or more reported allergies using statistical methods. Patients with 4 or more reported allergies ...
Kim Hyun Gun HG Institute for Digestive Research, Soonchunhyang University, College of Medicine, Seoul, - - 2014
This study investigated the conditions and predictive factors for adequate bowel preparation using the 4-L polyethylene (PEG) preparation in clinical practice. We conducted a prospective-survey-based observational study. The survey consisted of 14 questions that assessed the preparation method (group 1: split method for morning colonoscopy; group 2: full-volume method for ...
Giugliani Roberto R Medical Genetics Service, HCPA, Department of Genetics, UFRGS, and INAGEMP, Porto Alegre, - - 2014
Mucopolysaccharidosis VI (MPS VI) is a clinically heterogeneous and progressive disorder with multiorgan manifestations caused by deficient N-acetylylgalactosamine-4-sulfatase activity. A cross-sectional Survey Study in individuals (n = 121) affected with MPS VI was conducted between 2001 and 2002 to establish demographics, urinary glycosaminoglycan (GAG) levels, and clinical progression of disease. We conducted ...
Savani Gina M GM Department of Endodontology, School of Dentistry, Oregon Health and Science University, Portland, - - 2014
In the United States almost 70% of root canal treatment (RCT) is performed by general dentists (GPs), yet little is known about their treatment protocols. A paper survey was mailed to 2000 United States GPs with questions about the types of endodontic cases treated, routine treatment protocols, use of newer ...
Murakawa Yuji Y Fourth Department of Internal Medicine, Teikyo - - 2014
Background: A nationwide survey of catheter ablation for atrial fibrillation (AF) was conducted in Japan to determine the mid-term performance of the therapy from analysis of the 1-year outcome of registered patients. Methods and Results: A total of 2,137 patients who underwent AF ablation in September 2011 and March 2012 were initially ...
Shokohi Tahereh T Department of Parasitology and Mycology, Mazandaran University of Medical Sciences, Sari, IR Iran ; Invasive Fungi Research center, Mazandaran University of Medical Sciences, Sari, IR - - 2014
Fungal prosthetic valve endocarditis (PVE) is rare but serious complication of valve replacement surgery. Candida species, particularly Candida albicans is the most common isolated pathogen in fungal PVE (1-6%of cases). We describe a 35-year-old woman who underwent mechanical mitral valve replacement about 3 years ago. She was admitted with neurological ...
Palazzo Clémence - - 2014
Between 7% and 15% of patients are dissatisfied after total hip arthroplasty (THA). To assess predictors and postoperative determinants of satisfaction and expectation fulfilment one year after (THA). Before THA surgery, 132 patients from three tertiary care centres and their surgeons were interviewed to assess their expectations using the Hospital ...
Turan Tanya N TN Medical University of South Carolina, Charleston, S.C., - - 2014
Background and Purpose: Medical and endovascular treatment options for stroke prevention in patients with symptomatic intracranial stenosis have evolved over the past several decades, but the impact of 2 major multicenter randomized stroke prevention trials on physician practices has not been studied. We sought to determine changes in US physician ...
Fraumann Sarah A SA Division of Pediatric Urology, Monroe Carell Jr. Children's Hospital at Vanderbilt, 4012 Doctors' Office Tower, 2200 Children's Way, Nashville, TN 37232-9820, - - 2014
Few studies of hypospadias repair in childhood have used validated questionnaires to investigate outcomes of cosmesis, urinary function, and sexual function in adulthood. We sought to investigate long-term outcomes in adult patients who had undergone severe hypospadias repair as children using an existing web-based application available to multiple institutions in ...
Bojcic Jamie L JL Project Manager for St Joseph Heritage Health System in Irvine, and former Clinical Project Manager for the Surgical Outcomes and Analysis Department at Kaiser Permanente in San Diego, CA. - - 2014
This study compared response rates of paper and electronic versions of the Knee injury Osteoarthritis and Outcome Score questionnaire and examined the characteristics of patients who responded to each survey method. A total of 1486 patients registered by the Kaiser Permanente Anterior Cruciate Ligament Reconstruction Registry between 2005 and 2010 ...
Beugnet Frédéric F Merial, 29 avenue Tony Garnier, 69007 Lyon, - - 2014
A study based on naturally infested cats was designed to evaluate the effectiveness of a single treatment with a topical formulation containing fipronil, (S)-methoprene, eprinomectin and praziquantel, for the prevention of Otodectes cynotis infestation in cats. Six treated cats and six untreated cats were housed with three chronically Otodectes cynotis-infested ...
Wu Cong C Sichuan University, West China Hospital, Department of Neurosurgery, Chengdu Sichuan, - - 2014
To compare the effects of post neurosurgical antimicrobial prophylaxis before and after the adoption of a new protocol in our department, which changed from prolonged prophylaxis to limited usage. Two cross-sectional studies were performed to compare the 24-hour antimicrobial use for all the inpatients at the neurosurgical ward 1 day ...
Epstein Nancy E NE Chief of Neurosurgical Spine and Education, Winthrop University Hospital, Mineola, NY, - - 2014
Although fibrin sealants (FSs) and fibrin glues (FGs) are predominantly utilized to strengthen repairs of cerebrospinal fluid (CSF) fistulas (deliberate/traumatic) during spinal surgery, they are also increasingly utilized to achieve hemostasis. Here, we investigated whether adding Tisseel (Baxter International Inc., Westlake Village, CA, USA), utilized to address increased bleeding during ...
Lu Bin B Department of Ophthalmology, Children's Hospital, Zhejiang University School of Medicine, Hangzhou 310006, Zhejiang Province, - - 2014
To evaluate the effect of reducing the use of antibiotics in the treatment of infant bacterial dacryocystitis after probing of the lacrimal duct. A total of 542 cases of children under one year old and accepting nasolacrimal duct probing treatment were divided into two groups, which were treated with topical ...
Hannon Edward E Department of Paediatric Surgery, St George's Hospital, Tooting, London, UK. Electronic address: - - 2014
To define current UK reduction practice and the reductions rates achieved. Electronic surveys were sent to radiologists at 26 UK centres. This assessed methods of reduction, equipment, personnel, and protocol usage. Standardized audit proforma were also sent to evaluate all reductions performed in 2011. Twenty-two of 26 centres (85%) replied. ...
Leshem Eyal - - 2013
Current guidelines recommend continuation of atovaquone-proguanil (AP) malaria prophylaxis for 7 days after leaving Plasmodium falciparum endemic areas. Evidence from clinical studies suggests that discontinuation of AP 1 day after exposure ends may be safe and effective. Our objective was to assess the effectiveness of short-course AP prophylaxis among travelers ...
Pang Yong-Kek YK Department of Medicine, Faculty of Medicine, University of Malaya Medical Centre, University of Malaya Kuala Lumpur, - - 2013
A patient with Mycobacterium abscessus lung disease was mistaken to have pulmonary tuberculosis with airway colonization by the non-tuberculous mycobacterium. Appropriate antibiotics were only given when the patient's signs and symptoms worsened while on anti-tuberculosis therapy. Despite treatment with a combination of antibiotics showing in vitro susceptibility, the pathogen persisted ...
Abdel Messih Marena - - 2013
Telephone and postal methods of administration of the Oxford Knee Score (OKS) and the Oxford Hip Score (OHS) were compared on 85 and 61 patients undergoing total knee arthroplasty (TKA) and total hip arthroplasty (THA), respectively. The test for equivalence was significant for both the knee (P<0.001) and hip participants ...
Nasr Ahmed - - 2013
There is considerable controversy regarding optimal mode and timing of delivery for fetuses with gastroschisis. Our objectives were to describe the variation in institutional approach regarding these factors, and to evaluate the effect of timing of delivery on outcomes in fetuses with gastroschesis. Members of the maternal-fetal medicine community across ...
Adler Eldad - - 2013
To evaluate the current standard of care of ophthalmologists who are likely to encounter ocular surface squamous neoplasia (OSSN) in their practices and to compare this with data gathered in 2003. Invitations to a web-based survey were sent to members of the Ocular Microbiology and Immunology Group. In addition, the ...
Johnson Sidney M SM Department of Pediatric Surgery, Kapiolani Medical Center, University of Hawaii, John A. Burns School of Medicine, Honolulu, HI, USA. Electronic address: - - 2014
Cardiac or major vascular perforation is a rare but serious risk of ECMO. We sought to determine if perforation rates are related to cannula design. We utilized three methods to evaluate perforation on ECMO. 1. The ELSO registry was queried to establish the historical rate of hemorrhagic pericardial tamponade. 2. ...
Lehman Ronald A RA - - 2013
There are no guidelines for when surgeons should allow patients to return to sports and athletic activities after spinal fusion for adolescent idiopathic scoliosis (AIS). Current recommendations are based on anecdotal reports and a survey performed more than a decade ago in the era of first/second-generation posterior implants. To identify ...
Kim Gi Beom - - 2013
To assess the recent epidemiologic features of Kawasaki disease (KD) in South Korea from the nationwide survey conducted between 2009 and 2011. We collected data regarding the incidence, symptoms, treatment, and coronary complications associated with acute KD by sending questionnaires to the 100 hospitals that have pediatric residency programs from ...
1 2 3 4 5 6 7 8 9 10 >